Detailed information for compound 913696

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 624.769 | Formula: C30H52N6O8
  • H donors: 6 H acceptors: 7 LogP: 1.5 Rotable bonds: 25
    Rule of 5 violations (Lipinski): 3
  • SMILES: COC(=O)/C=C/[C@@H](NC(=O)CC[C@@H](C(=O)N)NC(=O)[C@@H](NC(=O)[C@@H](C(=O)NC(=O)[C@@H](N)C)CC(C)C)CC(C)C)CC(C)C
  • InChi: 1S/C30H52N6O8/c1-16(2)13-20(9-12-25(38)44-8)33-24(37)11-10-22(26(32)39)34-30(43)23(15-18(5)6)35-28(41)21(14-17(3)4)29(42)36-27(40)19(7)31/h9,12,16-23H,10-11,13-15,31H2,1-8H3,(H2,32,39)(H,33,37)(H,34,43)(H,35,41)(H,36,40,42)/b12-9+/t19-,20+,21-,22-,23-/m0/s1
  • InChiKey: UGTZMIVBSNZYQZ-BNZXQDRPSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis acetylcholinesterase 0.1638 0.7525 0.7525
Trypanosoma cruzi Aph-1 protein, putative 0.0847 0.386 1
Echinococcus granulosus carboxylesterase 5A 0.1638 0.7525 0.7525
Echinococcus granulosus presenilin enhancer 2 0.0385 0.1723 0.1721
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0148 0.0148
Loa Loa (eye worm) RNA binding protein 0.0061 0.0223 0.0223
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0137 0.0134
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0035 0.01 0.0249
Onchocerca volvulus 0.0031 0.0083 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0137 0.0328
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0025
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0038 0.0113 0.0388
Loa Loa (eye worm) hypothetical protein 0.0292 0.129 0.129
Echinococcus granulosus shaker cognate 0.0015 0.0007 0.0005
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0023 0.0023
Brugia malayi hypothetical protein 0.0144 0.0605 0.0598
Schistosoma mansoni hypothetical protein 0.0073 0.0275 0.0268
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Echinococcus multilocularis presenilin enhancer 2 0.0385 0.1723 0.1721
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0038 0.0113 0.0509
Echinococcus multilocularis carboxylesterase 5A 0.1638 0.7525 0.7525
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0038 0.0113 0.0388
Loa Loa (eye worm) hypothetical protein 0.0057 0.0205 0.0205
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0015 0.0007 0.0005
Brugia malayi hypothetical protein 0.02 0.0866 0.0859
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0292 0.129 0.1284
Echinococcus granulosus intermediate filament protein 0.0028 0.007 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0223 0.0216
Mycobacterium leprae putative cytochrome p450 0.0038 0.0113 1
Onchocerca volvulus 0.0035 0.01 0.0249
Loa Loa (eye worm) hypothetical protein 0.0292 0.129 0.129
Mycobacterium tuberculosis Carboxylesterase LipT 0.043 0.1932 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0148 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0038 0.0113 0.0509
Trichomonas vaginalis Nicastrin precursor, putative 0.02 0.0866 0.4588
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.01 0.0337
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0083 0.0076
Entamoeba histolytica hypothetical protein 0.0073 0.0275 0.1309
Plasmodium vivax SET domain protein, putative 0.0031 0.0083 0.554
Loa Loa (eye worm) hypothetical protein 0.0035 0.01 0.01
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0038 0.0113 0.0509
Brugia malayi follicle stimulating hormone receptor 0.0269 0.1186 0.118
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.004 0.0132
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0083 0.115
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0137 0.0663
Brugia malayi Carboxylesterase family protein 0.0292 0.129 0.1284
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0038 0.0113 0.0509
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.01 0.0337
Echinococcus granulosus smad 0.0016 0.0015 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.006 0.0215 0.052
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0038 0.0113 0.0509
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0038 0.0113 0.0388
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0049 0.0166 0.0404
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0078 0.0076
Loa Loa (eye worm) hypothetical protein 0.0052 0.0178 0.0178
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.041 0.184 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0137 0.0538
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.01 0.0443
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0223 0.0223
Brugia malayi gamma-secretase subunit pen-2 0.0385 0.1723 0.1718
Brugia malayi Cytochrome P450 family protein 0.0056 0.0199 0.0192
Mycobacterium tuberculosis Conserved protein 0.0035 0.01 0.0443
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0038 0.0113 0.0509
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0008
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0015 0.0007 0.0005
Schistosoma mansoni neuroligin 3 (S09 family) 0.0292 0.129 0.1284
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0121 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0165 0.0702 0.1796
Loa Loa (eye worm) hypothetical protein 0.0035 0.01 0.01
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0042 0.0139
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0042 0.0146
Schistosoma mansoni voltage-gated potassium channel 0.018 0.0771 0.0765
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0614 0.0608
Loa Loa (eye worm) hypothetical protein 0.0035 0.01 0.01
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0121 0.0114
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0015 0.0007 0.0005
Brugia malayi Pre-SET motif family protein 0.0031 0.0083 0.0076
Echinococcus granulosus lamin dm0 0.0028 0.007 0.0068
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.041 0.184 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.01 0.0337
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0292 0.129 0.1288
Mycobacterium tuberculosis Conserved protein 0.0035 0.01 0.0443
Onchocerca volvulus 0.0247 0.1082 0.8295
Echinococcus multilocularis Nicastrin 0.02 0.0866 0.0864
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0121 0.8428
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0038 0.0113 0.0509
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.01 0.0234
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.01 0.0337
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0083 0.0076
Brugia malayi Smad1 0.0016 0.0015 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.01 0.0098
Brugia malayi intermediate filament protein 0.0028 0.007 0.0063
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0052 0.0095
Loa Loa (eye worm) hypothetical protein 0.0039 0.0121 0.0121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0148 0.0141
Echinococcus multilocularis potassium voltage gated channel protein 0.018 0.0771 0.0769
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0275 0.0268
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0116 0.0476 0.121
Brugia malayi hypothetical protein 0.0024 0.0052 0.0045
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0596 0.0593
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0023 0.0016
Mycobacterium leprae Conserved hypothetical protein 0.0038 0.0113 1
Echinococcus granulosus Smad4 0.0016 0.0015 0.0013
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0138 1
Onchocerca volvulus 0.0292 0.129 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.01 0.6937
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0052 0.3456
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0083 0.0076
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0121 0.0454
Schistosoma mansoni microtubule-associated protein tau 0.0722 0.3284 0.3279
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.004 0.0033
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0007
Trypanosoma brucei unspecified product 0.0022 0.0042 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0038 0.0113 0.0509
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0038 0.0113 0.0388
Entamoeba histolytica hypothetical protein 0.0073 0.0275 0.1309
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.01 0.0093
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0137 0.0134
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.004 0.197
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0137 0.0134
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.01 0.0443
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0023
Loa Loa (eye worm) Smad1 0.0016 0.0015 0.0015
Echinococcus multilocularis microtubule associated protein 2 0.0722 0.3284 0.3282
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0614 0.0612
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0038 0.0113 0.0509
Trichomonas vaginalis Nicastrin precursor, putative 0.02 0.0866 0.4588
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0148 0.0141
Echinococcus granulosus acetylcholinesterase 0.1638 0.7525 0.7525
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0042 0.0035
Brugia malayi Cytochrome P450 family protein 0.0118 0.0488 0.0481
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0015 0.0013
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.041 0.184 0.4747
Loa Loa (eye worm) hypothetical protein 0.0292 0.129 0.129
Trichomonas vaginalis esterase, putative 0.0035 0.01 0.0337
Loa Loa (eye worm) beta-lactamase 0.0035 0.01 0.01
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0042 0.004
Onchocerca volvulus 0.0035 0.01 0.0249
Schistosoma mansoni intermediate filament proteins 0.0028 0.007 0.0063
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0016 0.0013
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0016 0.0016
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0042 0.0035
Echinococcus multilocularis lamin 0.0028 0.007 0.0068
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0042 0.007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.004 0.004
Echinococcus multilocularis gamma secretase subunit aph 1 0.2173 1 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0138 0.2075
Loa Loa (eye worm) carboxylesterase 0.0292 0.129 0.129
Brugia malayi MH2 domain containing protein 0.024 0.1049 0.1043
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0137 0.0134
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0013
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.004 0.0076
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0299 0.1326 0.132
Onchocerca volvulus 0.0292 0.129 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0052 0.0052
Echinococcus multilocularis dna polymerase eta 0.0052 0.0178 0.0176
Echinococcus granulosus nicalin 0.0074 0.028 0.0277
Echinococcus granulosus potassium voltage gated channel protein 0.0015 0.0007 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0148 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0038 0.0113 0.0509
Brugia malayi Carboxylesterase family protein 0.1638 0.7525 0.7524
Schistosoma mansoni lamin 0.0028 0.007 0.0063
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.01 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0083 0.0076
Trichomonas vaginalis spcc417.12 protein, putative 0.0292 0.129 0.6943
Loa Loa (eye worm) acetyltransferase 0.0146 0.0614 0.0614
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0137 0.0134
Echinococcus granulosus Nicastrin 0.02 0.0866 0.0864
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0052 0.0095
Leishmania major hypothetical protein, conserved 0.0116 0.0476 0.2524
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.01 0.0443
Loa Loa (eye worm) hypothetical protein 0.0043 0.0137 0.0137
Echinococcus multilocularis Nicastrin 0.02 0.0866 0.0864
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.018 0.0771 0.0765
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0038 0.0113 0.0388
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.004 0.5
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.004 0.0126
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0038 0.0113 0.0388
Trichomonas vaginalis set domain proteins, putative 0.0247 0.1082 0.5788
Echinococcus granulosus lamin 0.0028 0.007 0.0068
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0042 0.007
Toxoplasma gondii hypothetical protein 0.0144 0.0605 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0292 0.129 0.6943
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0038 0.0113 0.0388
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0023 0.0021
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0008
Brugia malayi hypothetical protein 0.0292 0.129 0.1284
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0292 0.129 0.1284
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0042 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.02 0.0866 0.0866
Echinococcus multilocularis BC026374 protein (S09 family) 0.0292 0.129 0.1288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0137 0.0538
Leishmania major mitochondrial DNA polymerase beta 0.0348 0.155 0.8411
Onchocerca volvulus 0.0292 0.129 1
Schistosoma mansoni lamin 0.0028 0.007 0.0063
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.007 0.007
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0038 0.0113 0.0267
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0137 1
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0042 0.0083
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0042 0.007
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0038 0.0113 0.0509
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0038 0.0113 0.0388
Echinococcus multilocularis acetylcholinesterase 0.1638 0.7525 0.7525
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0348 0.155 0.4
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0943 0.0943
Brugia malayi Carboxylesterase family protein 0.1638 0.7525 0.7524
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0083 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0223 0.0216
Entamoeba histolytica hypothetical protein 0.0073 0.0275 0.1309
Leishmania major hypothetical protein, conserved 0.0035 0.01 0.0465
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0148 0.0141
Mycobacterium tuberculosis Conserved protein 0.0035 0.01 0.0443
Brugia malayi hypothetical protein 0.0016 0.0012 0.0005
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.01 0.01
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0199 0.0478
Echinococcus multilocularis GPCR, family 2 0.0018 0.0023 0.0021
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.004 0.0063
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0038 0.0113 0.0388
Entamoeba histolytica hypothetical protein 0.0074 0.028 0.1334
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0038 0.0113 0.0388
Schistosoma mansoni DNA polymerase eta 0.0052 0.0178 0.0171
Echinococcus multilocularis presenilin 0.041 0.184 0.1838
Brugia malayi Presenilin family protein 0.041 0.184 0.1834
Brugia malayi Presenilin spe-4 0.0144 0.0605 0.0598
Echinococcus granulosus potassium voltage gated channel subfamily A 0.018 0.0771 0.0769
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0138 0.0546
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0038 0.0113 0.0388
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.01 0.0098
Loa Loa (eye worm) carboxylesterase 0.0292 0.129 0.129
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0038 0.0113 0.0388
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0083 0.0081
Brugia malayi Presenilin-like protein At2g29900 0.0144 0.0605 0.0598
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0038 0.0113 0.0388
Loa Loa (eye worm) hypothetical protein 0.0292 0.129 0.129
Onchocerca volvulus 0.0292 0.129 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0038 0.0113 0.0388
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0292 0.129 0.6649
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.01 0.0093
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.041 0.184 0.1834
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.01 0.0321
Brugia malayi hypothetical protein 0.0144 0.0605 0.0598
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0614 0.0608
Trypanosoma brucei DNA polymerase eta, putative 0.0052 0.0178 0.0436
Brugia malayi TAR-binding protein 0.0061 0.0223 0.0216
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0038 0.0113 0.0509
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0199 0.0478
Schistosoma mansoni ap endonuclease 0.0022 0.004 0.0033
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0199 0.0491
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0015 0.0013
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0042 0.004
Brugia malayi Pre-SET motif family protein 0.0217 0.0943 0.0937
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0016
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0199 0.0843
Loa Loa (eye worm) hypothetical protein 0.0292 0.129 0.129
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0016 0.0014
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0205 0.0205
Echinococcus multilocularis musashi 0.0028 0.007 0.0068
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0015 0.0007 0.0005
Brugia malayi beta-lactamase family protein 0.0035 0.01 0.0093
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Brugia malayi Presenilin spe-4 0.0144 0.0605 0.0598
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0199 0.0199
Schistosoma mansoni gamma-secretase subunit aph-1 0.2173 1 1
Brugia malayi RNA binding protein 0.0061 0.0223 0.0216
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0138 0.2075
Echinococcus granulosus microtubule associated protein 2 0.0722 0.3284 0.3282
Loa Loa (eye worm) voltage-gated potassium channel 0.0015 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Leishmania major DNA polymerase kappa, putative 0.0022 0.0042 0.0146
Echinococcus multilocularis Smad4 0.0016 0.0015 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0223 0.0216
Echinococcus granulosus BC026374 protein S09 family 0.0292 0.129 0.1288
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0166 0.0391
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.041 0.184 1
Echinococcus granulosus GPCR family 2 0.0018 0.0023 0.0021
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1638 0.7525 0.7524
Loa Loa (eye worm) carboxylesterase 0.1638 0.7525 0.7525
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.01 0.0443
Leishmania major DNA polymerase eta, putative 0.0052 0.0178 0.0891
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.01 0.0443
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0042 0.0015
Onchocerca volvulus 0.0292 0.129 1
Loa Loa (eye worm) acetylcholinesterase 1 0.1638 0.7525 0.7525
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0138 0.0135
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0166 0.0391
Trypanosoma cruzi Nicastrin, putative 0.0074 0.028 0.0687
Brugia malayi Carboxylesterase family protein 0.0292 0.129 0.1284
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0148 0.0146
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0208 0.0902 0.6823
Schistosoma mansoni voltage-gated potassium channel 0.018 0.0771 0.0765
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.0968 0.4972
Loa Loa (eye worm) hypothetical protein 0.0035 0.01 0.01
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.004 0.0037
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0015 0.0013
Echinococcus granulosus dna polymerase kappa 0.0022 0.0042 0.004
Schistosoma mansoni cytochrome P450 0.0038 0.0113 0.0106
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0223 0.0216
Entamoeba histolytica hypothetical protein 0.0073 0.0275 0.1309
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0016
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0038 0.0113 0.0388
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0165 0.0702 0.3761
Echinococcus multilocularis potassium voltage gated channel protein 0.0015 0.0007 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0183 0.0788 0.403
Brugia malayi hypothetical protein 0.0144 0.0605 0.0598
Echinococcus granulosus presenilin 0.041 0.184 0.1838
Schistosoma mansoni smad 0.0016 0.0015 0.0008
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.004 0.2279
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0015 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0023 0.0021
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0042 0.0035
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0107 0.1554
Trypanosoma brucei Aph-1 protein, putative 0.0847 0.386 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.0166 0.0391
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0038 0.0113 0.0254
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0137 0.0315
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0038 0.0113 0.0535
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.01 0.0337
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.01 0.0321
Mycobacterium ulcerans hypothetical protein 0.0183 0.0788 0.3954
Echinococcus granulosus dna polymerase eta 0.0052 0.0178 0.0176
Brugia malayi Presenilin spe-4 0.0144 0.0605 0.0598
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0016 0.0013
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0113 0.0254
Trypanosoma brucei Nicastrin, putative 0.0074 0.028 0.07
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0007 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0038 0.0113 0.0509
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0016 0.0014
Echinococcus granulosus cytochrome P450 2K1 0.0038 0.0113 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0038 0.0113 0.0509
Brugia malayi beta-lactamase family protein 0.0035 0.01 0.0093
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.2173 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0148 0.0146
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0172 0.0735 0.0733
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0038 0.0113 0.0388
Echinococcus multilocularis lamin dm0 0.0028 0.007 0.0068
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0042 0.004
Trypanosoma cruzi Aph-1 protein, putative 0.0847 0.386 1
Mycobacterium ulcerans beta-lactamase 0.0035 0.01 0.0321
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0038 0.0113 0.0509
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0015 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0035 0.01 0.01
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0137 0.0134
Loa Loa (eye worm) cytochrome P450 0.0038 0.0113 0.0113
Brugia malayi isocitrate dehydrogenase 0.0016 0.0016 0.0009
Toxoplasma gondii hypothetical protein 0.0056 0.0199 0.3115
Schistosoma mansoni Smad4 0.0016 0.0015 0.0008
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0016 0.0009
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0042 0.0014
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.041 0.184 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0052 0.0178 0.0423
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0038 0.0113 0.0509
Loa Loa (eye worm) hypothetical protein 0.018 0.0771 0.0771
Echinococcus multilocularis smad 0.0016 0.0015 0.0013
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.041 0.184 0.4754
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0199 0.0199
Echinococcus granulosus potassium voltage gated channel protein 0.018 0.0771 0.0769
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0016
Echinococcus multilocularis 0.0038 0.0113 0.0111
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0023 0.0021
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0023 0.0021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0205 0.0198
Mycobacterium ulcerans hypothetical protein 0.0035 0.01 0.0321
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0015 0.0007 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0118 0.0488 0.0488
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0107 0.0238
Loa Loa (eye worm) hypothetical protein 0.0028 0.0068 0.0068
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0292 0.129 0.1288
Giardia lamblia DINP protein human, muc B family 0.0022 0.0042 0.0271
Loa Loa (eye worm) hypothetical protein 0.0292 0.129 0.129
Toxoplasma gondii ABC1 family protein 0.0035 0.01 0.144
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0223 0.0223
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0038 0.0113 0.0388
Mycobacterium ulcerans carboxylesterase, LipT 0.043 0.1932 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0083 0.0083
Brugia malayi Carboxylesterase family protein 0.0292 0.129 0.1284
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0137 0.0538
Loa Loa (eye worm) intermediate filament protein 0.0028 0.007 0.007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0083 0.0081
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0038 0.0113 0.0388
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0348 0.155 0.3992
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0165 0.0702 0.1785
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0137 0.0315
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0015 0.0015
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0292 0.129 0.6649
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.01 0.0221
Brugia malayi cytochrome P450 0.0038 0.0113 0.0106
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0042 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0223 0.0216
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0292 0.129 0.129
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0042 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0137 0.0538
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0042 0.0139
Brugia malayi ImpB/MucB/SamB family protein 0.0052 0.0178 0.0171
Echinococcus granulosus neuroligin 0.0292 0.129 0.1288
Loa Loa (eye worm) hypothetical protein 0.1638 0.7525 0.7525
Leishmania major cytochrome p450-like protein 0.0038 0.0113 0.0535
Schistosoma mansoni gliotactin 0.0292 0.129 0.1284
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.0008
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0015 0.0007 0.0005
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0008
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0845 0.385 0.3849
Loa Loa (eye worm) hypothetical protein 0.1638 0.7525 0.7525
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0013
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0042 0.0083
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.01 0.0221
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0137 0.013
Schistosoma mansoni BC026374 protein (S09 family) 0.0292 0.129 0.1284
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0275 0.0273
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0223 0.0216
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0038 0.0113 0.0388
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.0008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0275 0.0273
Leishmania major hypothetical protein, conserved 0.0024 0.0052 0.02
Brugia malayi Cytochrome P450 family protein 0.0038 0.0113 0.0106
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0052 0.2989
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0015 0.0015
Brugia malayi hypothetical protein 0.02 0.0866 0.0859
Brugia malayi Cytochrome P450 family protein 0.0056 0.0199 0.0192
Echinococcus granulosus acetylcholinesterase 0.1638 0.7525 0.7525
Toxoplasma gondii hypothetical protein 0.0116 0.0476 0.7814
Toxoplasma gondii exonuclease III APE 0.0022 0.004 0.0409
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0223 0.022
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0137 0.013
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.1049 0.1049
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0038 0.0113 0.0509
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0016
Leishmania major cytochrome p450-like protein 0.0056 0.0199 0.1006
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0052 0.3456
Echinococcus multilocularis nicalin 0.0074 0.028 0.0277
Echinococcus granulosus para nitrobenzyl esterase 0.0292 0.129 0.1288
Echinococcus multilocularis transfer RNA-Gly 0.0015 0.0007 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0042 0.0083
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0015 0.0013
Echinococcus granulosus tar DNA binding protein 0.0061 0.0223 0.022
Schistosoma mansoni hypothetical protein 0.0038 0.0113 0.0106
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0038 0.0113 0.0509
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.01 0.0443
Echinococcus multilocularis para nitrobenzyl esterase 0.0292 0.129 0.1288
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.0008
Echinococcus multilocularis potassium voltage gated channel protein 0.0015 0.0007 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0013
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0205 0.0198
Trypanosoma cruzi Nicastrin, putative 0.0074 0.028 0.0687
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0385 0.1723 0.1723
Leishmania major cytochrome p450-like protein 0.0038 0.0113 0.0535
Loa Loa (eye worm) hypothetical protein 0.0028 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0208 0.0902 0.0902
Echinococcus granulosus potassium voltage gated channel protein 0.0015 0.0007 0.0005
Leishmania major DNA polymerase eta, putative 0.0036 0.0107 0.0502
Echinococcus multilocularis shaker cognate 0.0015 0.0007 0.0005
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.041 0.184 0.4747
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0137 0.013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.004 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0042 0.007
Brugia malayi hypothetical protein 0.0073 0.0275 0.0268
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.01 0.0093
Schistosoma mansoni hypothetical protein 0.02 0.0866 0.0859
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0269 0.1186 0.1186
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0009 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0148 0.0146
Schistosoma mansoni ap endonuclease 0.0022 0.004 0.0033
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0038 0.0113 0.0388
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0016 0.0009
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0113 0.0254
Brugia malayi Carboxylesterase family protein 0.0292 0.129 0.1284
Brugia malayi N-terminal motif family protein 0.0208 0.0902 0.0896
Toxoplasma gondii cytochrome p450 superfamily protein 0.0038 0.0113 0.1655
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0052 0.062
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0348 0.155 0.3992
Echinococcus multilocularis neuroligin 0.0292 0.129 0.1288
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.004 0.5
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.004 0.0037
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0138 0.0546
Echinococcus granulosus gamma secretase subunit aph 1 0.2173 1 1
Schistosoma mansoni hypothetical protein 0.0039 0.0121 0.0114
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.1049 0.1049
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.01 0.0443
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0052 0.0109
Brugia malayi beta-lactamase 0.0035 0.01 0.0093
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.007 0.0063
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0042 0.0042
Loa Loa (eye worm) presenilin spe-4 0.0144 0.0605 0.0605
Entamoeba histolytica presenilin 1 peptidase, putative 0.041 0.184 1
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0042 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0038 0.0113 0.0509
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0013
Schistosoma mansoni acetylcholinesterase 0.0292 0.129 0.1284
Mycobacterium ulcerans lipase LipD 0.0035 0.01 0.0321
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0023 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0038 0.0113 0.0509

Activities

Activity type Activity value Assay description Source Reference
T1/2 (ADMET) = 73.2 min Metabolic stability in human plasma assessed as half life after 360 mins ChEMBL. 19250821

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.