Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Pre-SET motif family protein | 0.0214 | 0.2568 | 0.4116 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0056 | 0.0431 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0431 | 0.0691 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0158 | 0.1814 | 0.3415 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0044 | 0.0268 | 0.0265 |
Schistosoma mansoni | cpg binding protein | 0.0045 | 0.0284 | 0.0282 |
Schistosoma mansoni | rab6-interacting | 0.0044 | 0.0268 | 0.0265 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0044 | 0.0268 | 0.0672 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0081 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0707 | 0.1211 |
Mycobacterium tuberculosis | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic | 0.0315 | 0.3946 | 0.5839 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0133 | 0.1476 | 0.2527 |
Onchocerca volvulus | 0.0163 | 0.1882 | 0.6242 | |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0191 | 0.2268 | 0.2266 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0044 | 0.0272 | 0.0665 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0003 | 0.0005 |
Entamoeba histolytica | hypothetical protein | 0.0184 | 0.2171 | 0.5359 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0081 | 0.0139 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0302 | 0.03 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0231 | 0.2809 | 0.2807 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0044 | 0.0272 | 0.0269 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0323 | 0.405 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0184 | 0.2171 | 0.5359 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0076 | 0.0707 | 0.0705 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0081 | 0.0139 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0036 | 0.0082 |
Echinococcus granulosus | snurportin 1 | 0.0348 | 0.4389 | 0.4387 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0486 | 0.6255 | 1 |
Mycobacterium leprae | PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC | 0.0315 | 0.3946 | 1 |
Echinococcus granulosus | zinc finger protein | 0.0128 | 0.1408 | 0.1405 |
Schistosoma mansoni | hypothetical protein | 0.0348 | 0.4389 | 0.4387 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0044 | 0.0272 | 0.0269 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.1476 | 0.1474 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.5841 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0214 | 0.2568 | 0.4396 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0707 | 0.1741 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0184 | 0.2171 | 1 |
Brugia malayi | Doublecortin family protein | 0.0044 | 0.0268 | 0.0429 |
Leishmania major | basic transcription factor 3a, putative | 0.0184 | 0.2171 | 1 |
Echinococcus multilocularis | RUN | 0.0044 | 0.0268 | 0.0265 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0076 | 0.0707 | 0.1211 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.0431 | 0.1975 |
Schistosoma mansoni | hypothetical protein | 0.0291 | 0.361 | 0.3608 |
Echinococcus multilocularis | peregrin | 0.0045 | 0.0288 | 0.0285 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0141 | 0.1586 | 0.1584 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.0675 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0879 | 0.1505 |
Plasmodium falciparum | importin beta, putative | 0.0033 | 0.0119 | 0.0295 |
Schistosoma mansoni | rab6-interacting | 0.0044 | 0.0268 | 0.0265 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0044 | 0.0272 | 0.0665 |
Onchocerca volvulus | 0.0031 | 0.01 | 0.0065 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0231 | 0.2809 | 0.2807 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0033 | 0.0119 | 0.0537 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.011 | 0.1164 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.1586 | 0.2716 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0164 | 0.0263 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0147 | 0.1666 | 0.1664 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.1 | 0.0997 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.0325 | 0.0322 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.0675 | 0.1156 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0119 | 0.0537 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0016 | 0.0013 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0348 | 0.4389 | 0.7513 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0076 | 0.0707 | 0.0705 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0158 | 0.1814 | 0.1994 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0268 | 0.0265 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.005 | 0.0357 | 0.0354 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0707 | 0.0705 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0348 | 0.4389 | 0.4387 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0044 | 0.0268 | 0.0265 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0386 | 0.4904 | 0.4903 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0302 | 0.03 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.0325 | 0.0556 |
Schistosoma mansoni | bromodomain containing protein | 0.0029 | 0.0074 | 0.0072 |
Onchocerca volvulus | 0.0048 | 0.0325 | 0.0844 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0075 | 0.0688 | 0.3161 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.3418 | 0.5852 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0056 | 0.0431 | 0.1975 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0707 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.3022 | 0.5173 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0707 | 0.1741 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0239 | 0.0237 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0076 | 0.0707 | 0.1134 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0511 | 0.0875 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0141 | 0.1586 | 0.1584 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0414 | 0.0709 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0003 | 0.0004 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0147 | 0.1666 | 0.1664 |
Leishmania major | hypothetical protein, conserved | 0.0099 | 0.1011 | 0.465 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0094 | 0.0151 |
Echinococcus granulosus | geminin | 0.0192 | 0.2271 | 0.2269 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0081 | 0.0079 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0184 | 0.2171 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0141 | 0.1586 | 0.1584 |
Schistosoma mansoni | eyes absent homolog | 0.0089 | 0.0879 | 0.0877 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.0325 | 0.0322 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0414 | 0.0412 |
Schistosoma mansoni | polycystin 1-related | 0.0044 | 0.0268 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.0192 | 0.2271 | 0.2269 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0707 | 0.3249 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0763 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0325 | 0.0556 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.0675 | 0.1083 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.1 | 0.1602 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0036 | 0.0082 |
Trypanosoma brucei | ISWI complex protein | 0.0099 | 0.1011 | 0.465 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.01 | 0.0098 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.011 | 0.1164 | 0.1162 |
Schistosoma mansoni | zinc finger protein | 0.0128 | 0.1408 | 0.1405 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0707 | 0.1134 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0076 | 0.0073 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.01 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0268 | 0.0458 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0056 | 0.0431 | 0.1086 |
Plasmodium vivax | importin-beta 2, putative | 0.0033 | 0.0119 | 0.0295 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0141 | 0.1586 | 0.1584 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0033 | 0.0119 | 0.019 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0707 | 0.1787 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0081 | 0.0195 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0707 | 0.1134 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0879 | 0.1505 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0414 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0272 | 0.0465 |
Echinococcus multilocularis | zinc finger protein | 0.0128 | 0.1408 | 0.1405 |
Echinococcus granulosus | RUN | 0.0044 | 0.0268 | 0.0265 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.0675 | 0.1083 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0081 | 0.02 |
Schistosoma mansoni | lipoxygenase | 0.0191 | 0.2268 | 0.2266 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0044 | 0.0272 | 0.1241 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0081 | 0.02 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0081 | 0.0363 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0044 | 0.0272 | 0.0269 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0302 | 0.0518 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0675 | 0.0673 |
Onchocerca volvulus | 0.0243 | 0.2966 | 1 | |
Loa Loa (eye worm) | beta-lactamase | 0.0076 | 0.0707 | 0.1211 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0386 | 0.4904 | 0.4903 |
Toxoplasma gondii | NAC domain-containing protein | 0.0184 | 0.2171 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0094 | 0.0161 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0414 | 0.0709 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0675 | 0.0673 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.011 | 0.1164 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0707 | 0.1211 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0044 | 0.0272 | 0.0269 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0056 | 0.0431 | 0.1975 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0044 | 0.0272 | 0.0269 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0033 | 0.0119 | 0.0117 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0191 | 0.2268 | 0.2266 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.0325 | 0.0322 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0414 | 0.0412 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0147 | 0.1666 | 0.1664 |
Echinococcus multilocularis | transcription factor btf3 | 0.0184 | 0.2171 | 0.2169 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0323 | 0.405 | 1 |
Brugia malayi | jmjC domain containing protein | 0.005 | 0.0357 | 0.0572 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0325 | 0.0322 |
Brugia malayi | hypothetical protein | 0.0163 | 0.1882 | 0.3017 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0414 | 0.0412 |
Onchocerca volvulus | 0.0044 | 0.0268 | 0.0646 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.0576 | 0.0574 |
Plasmodium vivax | nicotinate-nucleotide adenylyltransferase, putative | 0.0315 | 0.3946 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0675 | 0.0673 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0044 | 0.0272 | 0.0269 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0044 | 0.0272 | 0.0436 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0707 | 0.3249 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0707 | 0.1741 |
Brugia malayi | RNA binding protein | 0.0074 | 0.0675 | 0.1083 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0256 | 0.3142 | 0.538 |
Schistosoma mansoni | transcription factor btf3 | 0.0184 | 0.2171 | 0.2169 |
Onchocerca volvulus | 0.0031 | 0.0094 | 0.0045 | |
Loa Loa (eye worm) | ICD-1 protein | 0.0184 | 0.2171 | 0.3718 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0119 | 0.0537 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 0.2966 | 0.7321 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0081 | 0.0079 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.01 | 0.045 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.0431 | 0.1975 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0184 | 0.2171 | 0.5359 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0302 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0431 | 0.0738 |
Echinococcus granulosus | cpg binding protein | 0.0045 | 0.0284 | 0.0282 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0044 | 0.0272 | 0.1241 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0025 | 0.0016 | 0.0013 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0325 | 0.0322 |
Echinococcus multilocularis | cpg binding protein | 0.0045 | 0.0284 | 0.0282 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.01 | 0.0161 |
Echinococcus granulosus | transcription factor btf3 | 0.0184 | 0.2171 | 0.2169 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0707 | 0.1211 |
Echinococcus granulosus | importin subunit beta 1 | 0.0033 | 0.0119 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0707 | 0.1211 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0675 | 0.0673 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0239 | 0.0237 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0302 | 0.03 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0707 | 0.3249 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0094 | 0.0092 |
Onchocerca volvulus | 0.0076 | 0.0707 | 0.217 | |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0056 | 0.0431 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.037 | 0.0633 |
Brugia malayi | Importin beta-1 subunit | 0.0033 | 0.0119 | 0.0191 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0044 | 0.0272 | 0.0665 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0074 | 0.0127 |
Brugia malayi | PHD-finger family protein | 0.0162 | 0.1873 | 0.3002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0184 | 0.2171 | 0.5359 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0268 | 0.0458 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0044 | 0.0272 | 0.0269 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.01 | 0.0098 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.011 | 0.1164 | 0.1162 |
Schistosoma mansoni | importin beta-1 | 0.0033 | 0.0119 | 0.0117 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0302 | 0.0485 |
Trichomonas vaginalis | esterase, putative | 0.0076 | 0.0707 | 0.1741 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.0728 | 0.0725 |
Brugia malayi | Bromodomain containing protein | 0.0485 | 0.6238 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0409 | 0.5216 | 0.5215 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0044 | 0.0268 | 0.0265 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0188 | 0.2227 | 0.2225 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0166 | 0.0164 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0414 | 0.0664 |
Brugia malayi | follicle stimulating hormone receptor | 0.0256 | 0.3142 | 0.5038 |
Schistosoma mansoni | loxhd1 | 0.0044 | 0.0268 | 0.0265 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0675 | 0.0673 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0044 | 0.0268 | 0.0265 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0044 | 0.0272 | 0.1241 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.0675 | 0.1156 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0025 | 0.0016 | 0.0013 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0188 | 0.2227 | 0.2225 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0184 | 0.2171 | 0.55 |
Trypanosoma cruzi | ISWI complex protein | 0.0099 | 0.1011 | 0.465 |
Plasmodium falciparum | nicotinamide/nicotinic acid mononucleotide adenylyltransferase | 0.0315 | 0.3946 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0302 | 0.03 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0268 | 0.0429 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0272 | 0.0665 |
Schistosoma mansoni | cpg binding protein | 0.0045 | 0.0284 | 0.0282 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0081 | 0.0079 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0325 | 0.0521 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0323 | 0.405 | 1 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0184 | 0.2171 | 0.55 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0707 | 0.1741 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0707 | 0.1741 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0302 | 0.03 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0114 | 0.1217 | 0.2084 |
Onchocerca volvulus | 0.0076 | 0.0707 | 0.217 | |
Onchocerca volvulus | 0.0044 | 0.0268 | 0.0646 | |
Mycobacterium ulcerans | bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein | 0.0315 | 0.3946 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0076 | 0.0707 | 0.3249 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0081 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0119 | 0.0204 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.1 | 0.0997 |
Schistosoma mansoni | hypothetical protein | 0.0192 | 0.2271 | 0.2269 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0036 | 0.0082 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.0325 | 0.0844 |
Echinococcus granulosus | peregrin | 0.0045 | 0.0288 | 0.0285 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.01 | 0.0098 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.005 | 0.0357 | 0.061 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0268 | 0.0429 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0184 | 0.2171 | 0.5359 |
Brugia malayi | hypothetical protein | 0.0089 | 0.0879 | 0.141 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.1011 | 0.1009 |
Brugia malayi | RNA, U transporter 1 | 0.0093 | 0.0933 | 0.1495 |
Echinococcus multilocularis | tar DNA binding protein | 0.0074 | 0.0675 | 0.0673 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0044 | 0.0268 | 0.0265 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.005 | 0.0357 | 0.0354 |
Trypanosoma cruzi | ISWI complex protein | 0.0099 | 0.1011 | 0.465 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0044 | 0.0272 | 0.1241 |
Onchocerca volvulus | 0.0076 | 0.0707 | 0.217 | |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0044 | 0.0268 | 0.0265 |
Brugia malayi | beta-NAC-like protein | 0.0184 | 0.2171 | 0.3481 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.005 | 0.0357 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.1882 | 0.3221 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0763 | 1 | 1 |
Brugia malayi | beta-lactamase | 0.0076 | 0.0707 | 0.1134 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.0325 | 0.0322 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0158 | 0.1814 | 0.3415 |
Brugia malayi | Bromodomain containing protein | 0.0247 | 0.3016 | 0.4834 |
Echinococcus granulosus | tar DNA binding protein | 0.0074 | 0.0675 | 0.0673 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0707 | 0.0705 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0044 | 0.0272 | 0.0665 |
Echinococcus multilocularis | geminin | 0.0192 | 0.2271 | 0.2269 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.3228 | 0.5526 |
Leishmania major | importin beta-1 subunit, putative | 0.0026 | 0.0036 | 0.0152 |
Schistosoma mansoni | lipoxygenase | 0.0113 | 0.1206 | 0.1204 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0707 | 0.1211 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0044 | 0.0272 | 0.0269 |
Trichomonas vaginalis | importin beta-1, putative | 0.0026 | 0.0036 | 0.0082 |
Schistosoma mansoni | zinc finger protein | 0.0099 | 0.1011 | 0.1009 |
Loa Loa (eye worm) | doublecortin family protein | 0.0044 | 0.0268 | 0.0458 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0302 | 0.03 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0184 | 0.2171 | 1 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0026 | 0.0036 | 0.0152 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0325 | 0.0521 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0081 | 0.0363 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0414 | 0.0412 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.0325 | 0.0322 |
Brugia malayi | Bromodomain containing protein | 0.0045 | 0.0288 | 0.0461 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0044 | 0.0268 | 0.0672 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.0431 | 0.1975 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0076 | 0.0707 | 0.3249 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 60 uM | Inhibition of BoNT/A light chain metalloprotease activity | ChEMBL. | 17092934 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.