Detailed information for compound 915356

Basic information

Technical information
  • TDR Targets ID: 915356
  • Name: (2S)-3-[[2-[3-(4-carbamimidoylphenyl)-4,5-dih ydro-1,2-oxazol-5-yl]acetyl]amino]-2-[(2-chlo rophenyl)methoxycarbonylamino]propanoic acid
  • MW: 501.92 | Formula: C23H24ClN5O6
  • H donors: 4 H acceptors: 4 LogP: 1.53 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(CC1ON=C(C1)c1ccc(cc1)C(=N)N)NC[C@@H](C(=O)O)NC(=O)OCc1ccccc1Cl
  • InChi: 1S/C23H24ClN5O6/c24-17-4-2-1-3-15(17)12-34-23(33)28-19(22(31)32)11-27-20(30)10-16-9-18(29-35-16)13-5-7-14(8-6-13)21(25)26/h1-8,16,19H,9-12H2,(H3,25,26)(H,27,30)(H,28,33)(H,31,32)/t16?,19-/m0/s1
  • InChiKey: KJTVEBJKRKXIEV-CVMIBEPCSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-3-[[2-[3-(4-carbamimidoylphenyl)-4,5-dihydroisoxazol-5-yl]acetyl]amino]-2-[(2-chlorophenyl)methoxycarbonylamino]propanoic acid
  • (2S)-3-[[2-[3-(4-carbamimidoylphenyl)-4,5-dihydroisoxazol-5-yl]-1-oxoethyl]amino]-2-[[(2-chlorophenyl)methoxy-oxomethyl]amino]propanoic acid
  • (2S)-3-[[2-[3-(4-amidinophenyl)-4,5-dihydroisoxazol-5-yl]acetyl]amino]-2-[(2-chlorobenzyl)oxycarbonylamino]propionic acid
  • (2S)-3-[2-[3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]ethanoylamino]-2-[(2-chlorophenyl)methoxycarbonylamino]propanoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.008 0.0604 0.0644
Schistosoma mansoni ap endonuclease 0.0024 0.0133 0.014
Brugia malayi Tachykinin-like peptides receptor 99D 0.0972 0.8012 1
Loa Loa (eye worm) G-protein coupled receptor 0.0972 0.8012 1
Schistosoma mansoni biogenic amine receptor 0.0972 0.8012 0.8564
Brugia malayi Esterase D 0.0038 0.025 0.0309
Echinococcus multilocularis g-protein coupled receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus granulosus allatostatin A receptor 0.0972 0.8012 0.8012
Brugia malayi exodeoxyribonuclease III family protein 0.0024 0.0133 0.0163
Echinococcus multilocularis geminin 0.0186 0.1482 0.148
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0009 0.0013 0.0673
Schistosoma mansoni adenoreceptor 0.0972 0.8012 0.8564
Echinococcus granulosus neuropeptide receptor A26 0.1211 1 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.006 0.044 0.0597
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0972 0.8012 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0972 0.8012 0.8564
Brugia malayi Smad1 0.0013 0.0046 0.0054
Schistosoma mansoni smad 0.0013 0.0046 0.0047
Echinococcus granulosus lamin dm0 0.0016 0.0073 0.007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0972 0.8012 0.8012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0079 0.0593 0.0591
Loa Loa (eye worm) hypothetical protein 0.0196 0.1567 0.1956
Echinococcus multilocularis Smad4 0.0013 0.0046 0.0044
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0433 1
Plasmodium falciparum thioredoxin reductase 0.0027 0.0157 1
Brugia malayi MH1 domain containing protein 0.0013 0.0046 0.0054
Echinococcus granulosus neuropeptide Y receptor 0.0972 0.8012 0.8012
Trypanosoma cruzi trypanothione reductase, putative 0.0027 0.0157 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0024 0.0133 0.8435
Schistosoma mansoni smad1 5 8 and 0.0013 0.0046 0.0047
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.006 0.044 0.0597
Onchocerca volvulus 0.0972 0.8012 1
Schistosoma mansoni hypothetical protein 0.0037 0.0246 0.0261
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0003
Onchocerca volvulus 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Onchocerca volvulus 0.0972 0.8012 1
Schistosoma mansoni amine GPCR 0.0972 0.8012 0.8564
Brugia malayi Calcitonin receptor-like protein seb-1 0.0117 0.0913 0.1136
Schistosoma mansoni hypothetical protein 0.015 0.1182 0.1261
Echinococcus granulosus alpha 1A adrenergic receptor 0.0972 0.8012 0.8012
Echinococcus multilocularis G-protein coupled receptor, putative 0.0972 0.8012 0.8012
Mycobacterium tuberculosis Probable reductase 0.006 0.044 0.0597
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Brugia malayi Thioredoxin reductase 0.0027 0.0157 0.0193
Echinococcus granulosus intermediate filament protein 0.0016 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Brugia malayi neuropeptide F receptor 0.0972 0.8012 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) hypothetical protein 0.0074 0.0553 0.069
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.0015 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0009 0.0013 0.0673
Mycobacterium ulcerans secreted antigen 85-C FbpC 0.0888 0.7314 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0009 0.0013 0.0673
Schistosoma mansoni hypothetical protein 0.0449 0.3667 0.3918
Mycobacterium leprae SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) 0.0888 0.7314 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0009 0.0013 0.0011
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0009 0.0013 0.5
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0972 0.8012 0.8012
Echinococcus granulosus Smad4 0.0013 0.0046 0.0044
Mycobacterium tuberculosis Possible conserved membrane protein 0.0038 0.025 0.0338
Echinococcus multilocularis fmrfamide receptor 0.0972 0.8012 0.8012
Brugia malayi hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0013 0.0046 0.0044
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0009 0.0013 0.0012
Brugia malayi TAR-binding protein 0.0037 0.0246 0.0303
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0972 0.8012 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0079 0.0593 0.0632
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.006 0.044 0.0597
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0018 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0067 0.0496 0.0674
Brugia malayi G-protein coupled receptor 0.0972 0.8012 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0024 0.0133 1
Schistosoma mansoni hypothetical protein 0.0037 0.0246 0.0261
Echinococcus granulosus cpg binding protein 0.0033 0.0214 0.0212
Echinococcus multilocularis fmrfamide receptor 0.0972 0.8012 0.8012
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0009 0.0013 0.0014
Echinococcus multilocularis sex peptide receptor 0.0972 0.8012 0.8012
Schistosoma mansoni biogenic amine (5HT) receptor 0.0972 0.8012 0.8564
Brugia malayi hypothetical protein 0.0972 0.8012 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0027 0.0157 0.0155
Loa Loa (eye worm) melatonin receptor type 1A 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis musashi 0.0016 0.0073 0.007
Onchocerca volvulus 0.0972 0.8012 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Mycobacterium tuberculosis Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) 0.0888 0.7314 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0009 0.0013 0.0673
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0037 0.0246 0.0306
Brugia malayi RNA recognition motif domain containing protein 0.0037 0.0246 0.0303
Echinococcus granulosus microtubule associated protein 2 0.1133 0.9356 0.9356
Echinococcus multilocularis GPCR, family 2 0.0037 0.0246 0.0244
Schistosoma mansoni cpg binding protein 0.0033 0.0214 0.0226
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis neuropeptide receptor A26 0.1211 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0972 0.8012 0.8012
Brugia malayi Serotonin receptor 0.0972 0.8012 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0972 0.8012 0.8564
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0087
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0972 0.8012 0.8564
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0017 0.0018
Brugia malayi hypothetical protein 0.0972 0.8012 1
Brugia malayi putative neuropeptide receptor 0.0972 0.8012 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0972 0.8012 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus granulosus lamin 0.0016 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni neuropeptide F-like receptor 0.0972 0.8012 0.8564
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.3667 0.3666
Echinococcus granulosus neuropeptide FF receptor 2 0.0972 0.8012 0.8012
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0045 0.0312 0.031
Mycobacterium ulcerans secreted antigen 85-B FbpB 0.0038 0.025 0.0338
Toxoplasma gondii NADPH-glutathione reductase 0.0009 0.0013 0.0242
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0117 0.0913 0.1139
Echinococcus multilocularis neuropeptide FF receptor 2 0.0972 0.8012 0.8012
Loa Loa (eye worm) MH2 domain-containing protein 0.0193 0.1542 0.1924
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0246 0.0244
Schistosoma mansoni hypothetical protein 0.0045 0.0312 0.0332
Toxoplasma gondii exonuclease III APE 0.0024 0.0133 0.3026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Echinococcus granulosus neuropeptides capa receptor 0.0972 0.8012 0.8012
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0067 0.0496 0.0674
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0972 0.8012 0.8012
Loa Loa (eye worm) TYRA-2 protein 0.0972 0.8012 1
Onchocerca volvulus 0.0972 0.8012 1
Echinococcus granulosus fmrfamide receptor 0.0972 0.8012 0.8012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0024 0.0133 0.8322
Mycobacterium ulcerans hypothetical protein 0.0038 0.025 0.0338
Brugia malayi Intermediate filament tail domain containing protein 0.0016 0.0073 0.0087
Echinococcus granulosus tachykinin peptides receptor 99D 0.0972 0.8012 0.8012
Echinococcus granulosus rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Onchocerca volvulus Huntingtin homolog 0.0074 0.0553 0.0605
Echinococcus multilocularis neuropeptides capa receptor 0.0972 0.8012 0.8012
Schistosoma mansoni opsin-like receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0003 0.0004
Schistosoma mansoni smad1 5 8 and 0.0013 0.0046 0.0047
Schistosoma mansoni amine GPCR 0.0972 0.8012 0.8564
Loa Loa (eye worm) hypothetical protein 0.0074 0.0553 0.069
Schistosoma mansoni hypothetical protein 0.0186 0.1482 0.1582
Loa Loa (eye worm) hypothetical protein 0.0016 0.0073 0.0091
Schistosoma mansoni biogenic amine (5HT) receptor 0.0972 0.8012 0.8564
Schistosoma mansoni biogenic amine receptor 0.0972 0.8012 0.8564
Mycobacterium tuberculosis Probable oxidoreductase 0.0067 0.0496 0.0674
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Loa Loa (eye worm) thioredoxin reductase 0.0027 0.0157 0.0196
Onchocerca volvulus 0.0972 0.8012 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0013 0.0046 0.0044
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus granulosus serotonin receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0003 0.0004
Mycobacterium ulcerans hypothetical protein 0.0038 0.025 0.0338
Echinococcus granulosus 7tm_1 domain containing protein 0.0972 0.8012 0.8012
Brugia malayi Melatonin receptor type 1A 0.0972 0.8012 1
Brugia malayi hypothetical protein 0.0074 0.0553 0.0686
Onchocerca volvulus Neuropeptide F receptor homolog 0.0972 0.8012 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Brugia malayi MH2 domain containing protein 0.0013 0.0046 0.0054
Brugia malayi hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni amine GPCR 0.0972 0.8012 0.8564
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0024 0.0133 0.8435
Onchocerca volvulus 0.0972 0.8012 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0024 0.0133 0.0131
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0972 0.8012 0.8012
Echinococcus multilocularis X box binding protein 1 0.015 0.1182 0.118
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0009 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Brugia malayi sulfakinin receptor protein 0.0972 0.8012 1
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0196 0.1567 0.1953
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0013 0.0046 0.0044
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0199 0.0248
Schistosoma mansoni smad1 5 8 and 0.0013 0.0046 0.0047
Brugia malayi hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0972 0.8012 0.8012
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0972 0.8012 0.8012
Schistosoma mansoni hypothetical protein 0.0008 0.0003 0.0001
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0972 0.8012 0.8012
Schistosoma mansoni myosin xvIII 0.0972 0.8012 0.8564
Echinococcus granulosus geminin 0.0186 0.1482 0.148
Onchocerca volvulus 0.0972 0.8012 1
Entamoeba histolytica hypothetical protein 0.0045 0.0312 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0027 0.0157 0.0155
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0079 0.0593 0.0591
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0024 0.0133 0.0178
Echinococcus granulosus tar DNA binding protein 0.0037 0.0246 0.0243
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0972 0.8012 1
Onchocerca volvulus 0.0972 0.8012 1
Echinococcus granulosus neuropeptides capa receptor 0.0972 0.8012 0.8012
Onchocerca volvulus 0.0972 0.8012 1
Schistosoma mansoni neuropeptide receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) TAR-binding protein 0.0037 0.0246 0.0306
Trypanosoma cruzi trypanothione reductase, putative 0.0009 0.0013 0.0673
Schistosoma mansoni cpg binding protein 0.0032 0.0199 0.021
Echinococcus granulosus sex peptide receptor 0.0972 0.8012 0.8012
Echinococcus multilocularis g protein coupled receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Trichomonas vaginalis ap endonuclease, putative 0.0024 0.0133 0.0794
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0024 0.0133 0.0166
Echinococcus multilocularis cpg binding protein 0.0033 0.0214 0.0212
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0972 0.8012 0.8564
Brugia malayi hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0246 0.026
Schistosoma mansoni lamin 0.0016 0.0073 0.0075
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0003 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0246 0.026
Loa Loa (eye worm) cytochrome P450 0.0008 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Onchocerca volvulus 0.0972 0.8012 1
Brugia malayi Cytochrome P450 family protein 0.0051 0.0359 0.0444
Echinococcus multilocularis g protein coupled receptor 0.0972 0.8012 0.8012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0024 0.0133 0.8435
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0079 0.0593 0.0591
Plasmodium vivax glutathione reductase, putative 0.0027 0.0157 1
Mycobacterium tuberculosis Conserved protein 0.0038 0.025 0.0338
Echinococcus multilocularis neuropeptide receptor 0.0972 0.8012 0.8012
Echinococcus multilocularis expressed protein 0.0009 0.0015 0.0013
Echinococcus multilocularis smad 0.0013 0.0046 0.0044
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0972 0.8012 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0009 0.0013 0.0673
Schistosoma mansoni neuropeptide F-like receptor 0.0972 0.8012 0.8564
Echinococcus granulosus dnaJ subfamily B 0.0449 0.3667 0.3666
Brugia malayi hypothetical protein 0.0972 0.8012 1
Brugia malayi G-protein coupled receptor 0.0972 0.8012 1
Onchocerca volvulus 0.0972 0.8012 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0972 0.8012 1
Echinococcus multilocularis neuropeptide Y receptor 0.0972 0.8012 0.8012
Schistosoma mansoni histamine h1 receptor 0.0972 0.8012 0.8564
Echinococcus granulosus 7TM GPCR rhodopsin 0.0972 0.8012 0.8012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.0246 0.0244
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Entamoeba histolytica endo-1,4-beta-xylanase, putative 0.0038 0.025 0.6547
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Schistosoma mansoni neuropeptide receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) transcription factor SMAD2 0.0193 0.1542 0.1924
Loa Loa (eye worm) esterase D 0.0038 0.025 0.0313
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) Smad1 0.0013 0.0046 0.0058
Schistosoma mansoni ferritin 0.0009 0.0015 0.0014
Schistosoma mansoni cytochrome P450 0.0008 0.0003 0.0001
Echinococcus granulosus expressed protein 0.0009 0.0015 0.0013
Schistosoma mansoni intermediate filament proteins 0.0016 0.0073 0.0075
Echinococcus multilocularis orexin receptor type 2 0.0972 0.8012 0.8012
Mycobacterium leprae SECRETED ANTIGEN 85-B FBPB (85B) (ANTIGEN 85 COMPLEX B) (MYCOLYL TRANSFERASE 85B) (FIBRONECTIN-BINDING PROTEIN B) (EXTRACELLULAR 0.0038 0.025 0.0338
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0079 0.0593 0.0632
Brugia malayi ORL1-like opioid receptor 0.0972 0.8012 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0009 0.0013 0.0014
Brugia malayi CXXC zinc finger family protein 0.0032 0.0199 0.0245
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0027 0.0157 0.0211
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.0015 0.0016
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) neuropeptide F receptor 0.0972 0.8012 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0079 0.0593 0.0737
Echinococcus granulosus biogenic amine 5HT receptor 0.0972 0.8012 0.8012
Brugia malayi GnHR receptor homolog 0.0972 0.8012 1
Echinococcus multilocularis allatostatin A receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis neuropeptides capa receptor 0.0972 0.8012 0.8012
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Schistosoma mansoni hypothetical protein 0.0186 0.1482 0.1582
Mycobacterium leprae Secreted antigen 85A FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0038 0.025 0.0338
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Schistosoma mansoni hypothetical protein 0.0972 0.8012 0.8564
Loa Loa (eye worm) CYP4Cod1 0.0008 0.0003 0.0004
Treponema pallidum bacterioferrin (TpF1) 0.0009 0.0015 0.013
Echinococcus multilocularis tar DNA binding protein 0.0037 0.0246 0.0243
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0246 0.0307
Treponema pallidum exodeoxyribonuclease (exoA) 0.0024 0.0133 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0972 0.8012 0.8012
Brugia malayi glutathione reductase 0.0027 0.0157 0.0193
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) MH2 domain-containing protein 0.0013 0.0046 0.0058
Schistosoma mansoni amine GPCR 0.0972 0.8012 0.8564
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0009 0.0015 0.013
Echinococcus multilocularis neuropeptide receptor 0.0972 0.8012 0.8012
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.006 0.044 0.0597
Brugia malayi AKH receptor 0.0972 0.8012 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0009 0.0013 0.0242
Brugia malayi MH2 domain containing protein 0.0013 0.0046 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0009 0.0013 0.0673
Mycobacterium ulcerans secreted Mpt51/Mpb51 antigen protein FbpD 0.0038 0.025 0.0338
Mycobacterium tuberculosis Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-bind 0.0038 0.025 0.0338
Loa Loa (eye worm) histone methyltransferase 0.001 0.0018 0.0023
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0972 0.8012 1
Schistosoma mansoni Smad4 0.0013 0.0046 0.0047
Onchocerca volvulus Huntingtin homolog 0.0074 0.0553 0.0605
Schistosoma mansoni ferritin light chain 0.0009 0.0015 0.0014
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0009 0.0013 0.0013
Mycobacterium tuberculosis Probable dehydrogenase 0.006 0.044 0.0597
Loa Loa (eye worm) RNA binding protein 0.0037 0.0246 0.0306
Schistosoma mansoni ap endonuclease 0.0024 0.0133 0.014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.0246 0.0244
Mycobacterium ulcerans secreted antigen 85-A FbpA 0.0038 0.025 0.0338
Trichomonas vaginalis ferritin, putative 0.0009 0.0015 0.001
Schistosoma mansoni biogenic amine receptor 0.0972 0.8012 0.8564
Brugia malayi cytoplasmic intermediate filament protein 0.0009 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0013 0.0046 0.0058
Echinococcus granulosus neuropeptide receptor 0.0972 0.8012 0.8012
Echinococcus granulosus rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Brugia malayi hypothetical protein 0.0972 0.8012 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0972 0.8012 0.8012
Echinococcus granulosus dro:myosuppressin receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Entamoeba histolytica hypothetical protein 0.0045 0.0312 1
Schistosoma mansoni apoferritin-2 0.0009 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0117 0.0913 0.1139
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0246 0.0303
Brugia malayi Dopamine receptor protein 2 0.0972 0.8012 1
Schistosoma mansoni neuropeptide receptor 0.0972 0.8012 0.8564
Schistosoma mansoni ferritin 0.0009 0.0015 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.1133 0.9356 1
Brugia malayi follicle stimulating hormone receptor 0.0972 0.8012 1
Loa Loa (eye worm) G-protein coupled receptor 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Mycobacterium tuberculosis Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular 0.0038 0.025 0.0338
Loa Loa (eye worm) hypothetical protein 0.0037 0.0246 0.0307
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0359 0.0448
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Brugia malayi MH2 domain containing protein 0.0193 0.1542 0.1921
Echinococcus multilocularis G protein coupled receptor 139 0.0972 0.8012 0.8012
Echinococcus multilocularis somatostatin receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0079 0.0593 0.0591
Schistosoma mansoni hypothetical protein 0.0037 0.0246 0.0261
Brugia malayi intermediate filament protein 0.0016 0.0073 0.0087
Echinococcus multilocularis neuropeptide s receptor 0.1211 1 1
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0038 0.025 0.0338
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) glutathione reductase 0.0027 0.0157 0.0196
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0972 0.8012 0.8012
Echinococcus granulosus peptide allatostatin:somatostatin 0.0972 0.8012 0.8012
Echinococcus granulosus orexin receptor type 2 0.0972 0.8012 0.8012
Echinococcus multilocularis 0.0008 0.0003 0.0001
Echinococcus granulosus smad 0.0013 0.0046 0.0044
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni ferritin 0.0009 0.0015 0.0014
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0972 0.8012 0.8564
Schistosoma mansoni lamin 0.0016 0.0073 0.0075
Schistosoma mansoni opsin-like receptor 0.0972 0.8012 0.8564
Echinococcus granulosus GPCR family 2 0.0037 0.0246 0.0244
Brugia malayi hypothetical protein 0.0045 0.0312 0.0386
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) intermediate filament protein 0.0016 0.0073 0.0091
Echinococcus granulosus g protein coupled receptor 0.0972 0.8012 0.8012
Schistosoma mansoni ferritin light chain 0.0009 0.0015 0.0014
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0972 0.8012 1
Echinococcus granulosus neuropeptide Y receptor 0.0972 0.8012 0.8012
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0024 0.0133 0.0178
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0045 0.0312 0.031
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0972 0.8012 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis serotonin receptor 0.0972 0.8012 0.8012
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0972 0.8012 0.8564
Plasmodium falciparum glutathione reductase 0.0027 0.0157 1
Echinococcus multilocularis S formylglutathione hydrolase 0.0038 0.025 0.0248
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0009 0.0013 0.0014
Schistosoma mansoni neuropeptide receptor 0.0972 0.8012 0.8564
Echinococcus multilocularis lamin 0.0016 0.0073 0.007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0246 0.0244
Schistosoma mansoni hypothetical protein 0.0972 0.8012 0.8564
Echinococcus granulosus mothers against decapentaplegic 5 0.0013 0.0046 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0972 0.8012 0.8012
Schistosoma mansoni growth hormone secretagogue receptor 0.0972 0.8012 0.8564
Mycobacterium ulcerans hypothetical protein 0.0038 0.025 0.0338
Schistosoma mansoni hypothetical protein 0.0972 0.8012 0.8564
Schistosoma mansoni transcription factor LCR-F1 0.0045 0.0312 0.0332
Echinococcus granulosus tm gpcr rhodopsin 0.0972 0.8012 0.8012
Onchocerca volvulus 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0067 0.0496 0.0674
Mycobacterium tuberculosis Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0038 0.025 0.0338
Trichomonas vaginalis conserved hypothetical protein 0.0191 0.1522 1
Echinococcus granulosus hypothetical protein 0.0972 0.8012 0.8012
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0024 0.0133 0.8322
Echinococcus granulosus g protein coupled receptor 0.0972 0.8012 0.8012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Trichomonas vaginalis ap endonuclease, putative 0.0024 0.0133 0.0794
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0015 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Schistosoma mansoni ferritin 0.0009 0.0015 0.0014
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0015 0.0016
Echinococcus multilocularis lamin dm0 0.0016 0.0073 0.007
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0972 0.8012 0.8564
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0493 0.0524
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0972 0.8012 0.8564
Echinococcus granulosus neuropeptide receptor 0.0972 0.8012 0.8012
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0024 0.0133 0.0131
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0013 0.0046 0.0047
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0972 0.8012 1
Brugia malayi MH1 domain containing protein 0.0013 0.0046 0.0054
Echinococcus multilocularis g protein coupled receptor 0.0972 0.8012 0.8012
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0079 0.0593 0.074
Echinococcus granulosus tm gpcr rhodopsin 0.0972 0.8012 0.8012
Onchocerca volvulus 0.0972 0.8012 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0009 0.0013 0.0673
Schistosoma mansoni alpha-1 adrenergic receptor 0.0972 0.8012 0.8564
Echinococcus granulosus rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Toxoplasma gondii thioredoxin reductase 0.0027 0.0157 0.3588
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0972 0.8012 0.8012
Schistosoma mansoni neuropeptide f receptor 76f 0.0972 0.8012 0.8564
Leishmania major trypanothione reductase 0.0027 0.0157 1
Brugia malayi hypothetical protein 0.0972 0.8012 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0972 0.8012 0.8012
Brugia malayi RNA binding protein 0.0037 0.0246 0.0303
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0246 0.026
Mycobacterium ulcerans hypothetical protein 0.0038 0.025 0.0338
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0016 0.0073 0.0091
Echinococcus multilocularis serotonin receptor 0.0972 0.8012 0.8012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0079 0.0593 0.0632
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0972 0.8012 0.8564
Plasmodium vivax thioredoxin reductase, putative 0.0027 0.0157 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.006 0.044 0.0597
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Schistosoma mansoni apoferritin-2 0.0009 0.0015 0.0014
Brugia malayi larval opioid receptor 0.0972 0.8012 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Onchocerca volvulus 0.0972 0.8012 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Mycobacterium tuberculosis Probable conserved exported protein 0.0038 0.025 0.0338
Onchocerca volvulus 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Echinococcus granulosus g protein coupled receptor 0.0972 0.8012 0.8012
Echinococcus granulosus X box binding protein 1 0.015 0.1182 0.118
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0024 0.0133 1
Trypanosoma brucei trypanothione reductase 0.0027 0.0157 1
Echinococcus granulosus G protein coupled receptor 139 0.0972 0.8012 0.8012
Loa Loa (eye worm) hypothetical protein 0.008 0.0604 0.0754
Onchocerca volvulus 0.0972 0.8012 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0972 0.8012 0.8012
Echinococcus granulosus tm gpcr rhodopsin 0.0972 0.8012 0.8012
Brugia malayi Dopamine receptor protein 1 0.0972 0.8012 1
Echinococcus multilocularis microtubule associated protein 2 0.1133 0.9356 0.9356
Brugia malayi RE15519p 0.0972 0.8012 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0117 0.0913 0.1136
Schistosoma mansoni cpg binding protein 0.0033 0.0214 0.0226
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0009 0.001 0.0012
Echinococcus granulosus g-protein coupled receptor 0.0972 0.8012 0.8012
Echinococcus granulosus somatostatin receptor 0.0972 0.8012 0.8012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0013 0.0673
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Brugia malayi hypothetical protein 0.0972 0.8012 1
Schistosoma mansoni opsin-like receptor 0.0972 0.8012 0.8564
Loa Loa (eye worm) neuropeptide F receptor 0.0972 0.8012 1
Loa Loa (eye worm) hypothetical protein 0.0972 0.8012 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0009 0.0013 0.0673
Brugia malayi neuropeptide F receptor 0.0972 0.8012 1
Echinococcus granulosus S formylglutathione hydrolase 0.0038 0.025 0.0248
Entamoeba histolytica hypothetical protein 0.0045 0.0312 1
Schistosoma mansoni amine GPCR 0.0972 0.8012 0.8564
Brugia malayi Serotonin receptor 0.0972 0.8012 1
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0246 0.026
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0009 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.0037 0.0246 0.0261
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0972 0.8012 1
Brugia malayi Dopamine receptor 0.0972 0.8012 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0972 0.8012 0.8012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0246 0.0303
Schistosoma mansoni hypothetical protein 0.0972 0.8012 0.8564
Echinococcus granulosus ferritin 0.0009 0.0015 0.0013
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0972 0.8012 0.8012
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0972 0.8012 0.8012
Brugia malayi latrophilin 2 splice variant baaae 0.008 0.0604 0.0751
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0972 0.8012 1
Brugia malayi putative neuropeptide receptor NPR1 0.0972 0.8012 1
Schistosoma mansoni tar DNA-binding protein 0.0037 0.0246 0.026
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0024 0.0133 0.8435
Entamoeba histolytica hypothetical protein 0.0045 0.0312 1
Echinococcus multilocularis ferritin 0.0009 0.0015 0.0013
Onchocerca volvulus 0.0032 0.0199 0.0159
Brugia malayi G protein-coupled receptor 0.0972 0.8012 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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