Detailed information for compound 915541

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 484.586 | Formula: C30H32N2O4++
  • H donors: 0 H acceptors: 0 LogP: 5.74 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1OCCCCCC[n+]1ccccc1)c[n+]1c(c2)c2cc3OCOc3cc2CC1
  • InChi: 1S/C30H32N2O4/c1-33-27-10-9-22-17-26-24-19-29-28(35-21-36-29)18-23(24)11-15-32(26)20-25(22)30(27)34-16-8-3-2-5-12-31-13-6-4-7-14-31/h4,6-7,9-10,13-14,17-20H,2-3,5,8,11-12,15-16,21H2,1H3/q+2
  • InChiKey: PARVUKRPMAIMOY-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0155 0.0346
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.081 0.4478 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.081 0.4478 1
Schistosoma mansoni amine GPCR 0.081 0.4478 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.081 0.4478 0.4476
Giardia lamblia Pyruvate kinase 0.0018 0.0034 0.0324
Loa Loa (eye worm) FYVE zinc finger family protein 0.0013 0.0004 0.001
Schistosoma mansoni pyruvate kinase 0.0036 0.0132 0.0294
Echinococcus multilocularis serotonin receptor 0.081 0.4478 0.4476
Entamoeba histolytica Ran family GTPase 0.0044 0.0175 0.1655
Brugia malayi Pip kinase protein 1 0.0013 0.0004 0.001
Brugia malayi gonadotropin-releasing hormone receptor 2 0.081 0.4478 1
Echinococcus multilocularis allatostatin A receptor 0.081 0.4478 0.4476
Echinococcus multilocularis neuropeptide FF receptor 2 0.081 0.4478 0.4476
Loa Loa (eye worm) transcription factor SMAD2 0.0129 0.0655 0.1462
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0166 0.1596
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0012 0.0074
Loa Loa (eye worm) hypothetical protein 0.0059 0.0263 0.0588
Entamoeba histolytica hypothetical protein 0.0048 0.02 0.1896
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.081 0.4478 0.4476
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.081 0.4478 0.4476
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1038 1
Echinococcus multilocularis pyruvate kinase 0.0018 0.0034 0.0029
Echinococcus granulosus dro:myosuppressin receptor 0.081 0.4478 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0175 0.6661
Brugia malayi Serotonin/octopamine receptor family protein 7 0.081 0.4478 1
Toxoplasma gondii exonuclease III APE 0.0042 0.0166 0.629
Onchocerca volvulus 0.081 0.4478 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.081 0.4478 0.4476
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0175 0.169
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.081 0.4478 1
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0079 0.0646
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0175 0.0171
Schistosoma mansoni amine GPCR 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0132 0.0294
Schistosoma mansoni ap endonuclease 0.0042 0.0166 0.037
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0299 0.2457
Loa Loa (eye worm) hypothetical protein 0.0164 0.0853 0.1904
Echinococcus multilocularis neuropeptide s receptor 0.081 0.4478 0.4476
Onchocerca volvulus Neuropeptide F receptor homolog 0.081 0.4478 1
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0013 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni alpha-glucosidase 0.0152 0.0781 0.1744
Echinococcus granulosus neuropeptide Y receptor 0.081 0.4478 1
Brugia malayi G protein-coupled receptor F59B2.13 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni kinase 0.01 0.0494 0.1102
Brugia malayi hypothetical protein 0.081 0.4478 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.081 0.4478 1
Echinococcus granulosus neuropeptide receptor A26 0.081 0.4478 1
Schistosoma mansoni importin beta-1 0.0059 0.0263 0.0588
Schistosoma mansoni alpha-1 adrenergic receptor 0.081 0.4478 1
Brugia malayi Muscleblind-like protein 0.0171 0.089 0.1987
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0166 0.0332
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.081 0.4478 1
Onchocerca volvulus 0.081 0.4478 1
Echinococcus multilocularis pyruvate kinase 0.0036 0.0132 0.0127
Echinococcus multilocularis snurportin 1 0.0634 0.3486 0.3484
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0132 0.0268
Onchocerca volvulus 0.0102 0.0503 0.11
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0155 0.1455
Echinococcus multilocularis orexin receptor type 2 0.081 0.4478 0.4476
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0004 0.0036
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0013 0.0004 0.001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0176 0.0919 0.2051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Leishmania major DNA polymerase kappa, putative 0.004 0.0155 0.1271
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0079 0.299
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0155 0.1271
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0013 0.0004 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.081 0.4478 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0132 0.0264
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.081 0.4478 1
Loa Loa (eye worm) G-protein coupled receptor 0.081 0.4478 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.015 0.0334
Schistosoma mansoni histamine h1 receptor 0.081 0.4478 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.081 0.4478 0.4476
Trypanosoma brucei unspecified product 0.0028 0.0085 0.0699
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Chlamydia trachomatis pyruvate kinase 0.0036 0.0132 0.5
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Leishmania major pyruvate kinase 0.0036 0.0132 0.1081
Echinococcus granulosus dna polymerase eta 0.0066 0.0299 0.0659
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0263 0.2162
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Brugia malayi hypothetical protein 0.081 0.4478 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.015 0.0325
Mycobacterium ulcerans secreted antigen 85-A FbpA 0.0038 0.0145 0.0291
Leishmania major hypothetical protein, conserved 0.0026 0.0079 0.0646
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1038 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.015 0.0145
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0145 0.1186
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.081 0.4478 1
Echinococcus granulosus muscleblind protein 0.0171 0.089 0.1979
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) neuropeptide F receptor 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0155 0.1271
Brugia malayi Melatonin receptor type 1A 0.081 0.4478 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0013 0.0004 0.0036
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0175 0.0392
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0132 0.0268
Schistosoma mansoni DNA polymerase eta 0.0066 0.0299 0.0669
Echinococcus multilocularis geminin 0.0703 0.3878 0.3875
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.015 0.1405
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.02 0.1896
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0013 0.0004 0.001
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0034 0.1279
Schistosoma mansoni neuropeptide f receptor 76f 0.081 0.4478 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.015 0.1405
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0079 0.299
Echinococcus multilocularis dna polymerase kappa 0.004 0.0155 0.0151
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0079 0.299
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0004 0.0036
Brugia malayi putative neuropeptide receptor 0.081 0.4478 1
Echinococcus multilocularis neuropeptide Y receptor 0.081 0.4478 0.4476
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0473 0.0469
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0155 0.1455
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0197 0.1038 0.8522
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.015 0.1228
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0155 0.1455
Brugia malayi hypothetical protein 0.05 0.2739 0.6115
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0155 0.1271
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0145 0.5489
Mycobacterium ulcerans secreted antigen 85-C FbpC 0.0902 0.4994 1
Schistosoma mansoni pyruvate kinase 0.0018 0.0034 0.0075
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0079 0.0719
Schistosoma mansoni hypothetical protein 0.0634 0.3486 0.7785
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Trypanosoma brucei glucosidase, putative 0.0039 0.015 0.1228
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0113 0.0925
Giardia lamblia Pyruvate kinase 0.0036 0.0132 0.1268
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0004 0.0036
Onchocerca volvulus 0.081 0.4478 1
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0164 0.0853 0.0849
Trypanosoma brucei DNA polymerase eta, putative 0.0066 0.0299 0.2457
Brugia malayi serine/threonine-protein kinase plk-2 0.0197 0.1038 0.2319
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Brugia malayi hypothetical protein 0.0017 0.0026 0.0058
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0079 0.0646
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0013 0.0004 0.001
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0013 0.0004 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0012 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1038 1
Brugia malayi Dopamine receptor 0.081 0.4478 1
Mycobacterium ulcerans hypothetical protein 0.0038 0.0145 0.0291
Leishmania major pyruvate kinase 0.0036 0.0132 0.1081
Brugia malayi Serotonin receptor 0.081 0.4478 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0004 0.0036
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0079 0.0646
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0079 0.0646
Echinococcus multilocularis pyruvate kinase 0.0018 0.0034 0.0029
Echinococcus multilocularis neuropeptide receptor 0.081 0.4478 0.4476
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0012 0.0099
Schistosoma mansoni neuropeptide receptor 0.081 0.4478 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.081 0.4478 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0166 0.0161
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0013 0.0004 0.0036
Trypanosoma brucei polo-like protein kinase 0.0197 0.1038 0.8522
Echinococcus granulosus peptide allatostatin:somatostatin 0.081 0.4478 1
Echinococcus granulosus neuropeptides capa receptor 0.081 0.4478 1
Schistosoma mansoni biogenic amine receptor 0.081 0.4478 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.081 0.4478 1
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0012 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0473 0.1057
Mycobacterium tuberculosis Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0038 0.0145 0.0136
Brugia malayi Tachykinin-like peptides receptor 99D 0.081 0.4478 1
Schistosoma mansoni amine GPCR 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0013 0.0004 0.001
Brugia malayi MH2 domain containing protein 0.0129 0.0655 0.1462
Entamoeba histolytica hypothetical protein 0.0038 0.0146 0.1367
Echinococcus granulosus g protein coupled receptor 0.081 0.4478 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0197 0.1038 0.2298
Mycobacterium ulcerans hypothetical protein 0.0038 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Brugia malayi hypothetical protein 0.0038 0.0146 0.0325
Schistosoma mansoni survival motor neuron protein 0.0102 0.0503 0.1123
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.081 0.4478 1
Schistosoma mansoni ran 0.0044 0.0175 0.0392
Brugia malayi hypothetical protein 0.081 0.4478 1
Schistosoma mansoni neuropeptide receptor 0.081 0.4478 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0146 0.0141
Brugia malayi larval opioid receptor 0.081 0.4478 1
Brugia malayi G-protein coupled receptor 0.081 0.4478 1
Onchocerca volvulus 0.081 0.4478 1
Brugia malayi hypothetical protein 0.081 0.4478 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0473 0.1048
Echinococcus granulosus tm gpcr rhodopsin 0.081 0.4478 1
Schistosoma mansoni biogenic amine receptor 0.081 0.4478 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0473 0.1057
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.05 0.2739 0.6115
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0155 0.0346
Echinococcus multilocularis neuropeptides capa receptor 0.081 0.4478 0.4476
Echinococcus granulosus tm gpcr rhodopsin 0.081 0.4478 1
Brugia malayi neuropeptide F receptor 0.081 0.4478 1
Entamoeba histolytica hypothetical protein 0.0038 0.0146 0.1367
Mycobacterium tuberculosis Conserved protein 0.0038 0.0145 0.0136
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.015 0.1405
Schistosoma mansoni biogenic amine (dopamine) receptor 0.081 0.4478 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0012 0.0074
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.015 0.1405
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1038 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0166 0.0361
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.02 0.1896
Brugia malayi ORL1-like opioid receptor 0.081 0.4478 1
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0013 0.0004 0.0036
Trichomonas vaginalis rotamase, putative 0.0033 0.0113 0.1048
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.081 0.4478 1
Echinococcus granulosus pyruvate kinase 0.0018 0.0034 0.0066
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0132 0.1232
Schistosoma mansoni biogenic amine (5HT) receptor 0.081 0.4478 1
Loa Loa (eye worm) pip kinase 2 0.0164 0.0853 0.1904
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0263 1
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0479 0.4589
Echinococcus granulosus dna polymerase kappa 0.004 0.0155 0.0336
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0012 0.0027
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0113 0.4281
Schistosoma mansoni hypothetical protein 0.0038 0.0146 0.0325
Echinococcus multilocularis g-protein coupled receptor 0.081 0.4478 0.4476
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.015 0.0334
Mycobacterium tuberculosis Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular 0.0038 0.0145 0.0136
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0132 0.1081
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0132 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0473 0.1048
Brugia malayi Importin beta-1 subunit 0.0059 0.0263 0.0588
Entamoeba histolytica hypothetical protein 0.0038 0.0146 0.1367
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0503 0.1123
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.015 0.1228
Echinococcus granulosus g protein coupled receptor 0.081 0.4478 1
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0079 0.0646
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Echinococcus granulosus neuropeptide receptor 0.081 0.4478 1
Mycobacterium tuberculosis Possible conserved membrane protein 0.0038 0.0145 0.0136
Echinococcus granulosus allatostatin A receptor 0.081 0.4478 1
Loa Loa (eye worm) melatonin receptor type 1A 0.081 0.4478 1
Leishmania major DNA polymerase eta, putative 0.0066 0.0299 0.2457
Onchocerca volvulus 0.081 0.4478 1
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0079 0.0074
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0197 0.1038 0.2311
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0004 0.0166
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0034 0.1279
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0085 0.0699
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.1038 0.8522
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0013 0.0004 0.0166
Brugia malayi Pip kinase protein 2 0.0164 0.0853 0.1904
Echinococcus multilocularis pyruvate kinase 0.0036 0.0132 0.0127
Echinococcus granulosus pyruvate kinase 0.0018 0.0034 0.0066
Schistosoma mansoni neuropeptide F-like receptor 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0071 0.0158
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0132 0.1232
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0263 0.2162
Loa Loa (eye worm) hypothetical protein 0.0066 0.0299 0.0669
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0166 0.5
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0117 0.0262
Trichomonas vaginalis ran, putative 0.0044 0.0175 0.1655
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0113 0.0925
Onchocerca volvulus 0.081 0.4478 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0155 0.0155
Loa Loa (eye worm) MH2 domain-containing protein 0.0129 0.0655 0.1462
Echinococcus granulosus neuropeptide FF receptor 2 0.081 0.4478 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0155 0.0336
Mycobacterium leprae SECRETED ANTIGEN 85-B FBPB (85B) (ANTIGEN 85 COMPLEX B) (MYCOLYL TRANSFERASE 85B) (FIBRONECTIN-BINDING PROTEIN B) (EXTRACELLULAR 0.0038 0.0145 0.0028
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0013 0.0004 0.0036
Brugia malayi hypothetical protein 0.081 0.4478 1
Echinococcus multilocularis g protein coupled receptor 0.081 0.4478 0.4476
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0146 0.0325
Echinococcus multilocularis alpha 1A adrenergic receptor 0.081 0.4478 0.4476
Echinococcus granulosus rhodopsin orphan GPCR 0.081 0.4478 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.081 0.4478 0.4476
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0027
Schistosoma mansoni hypothetical protein 0.0703 0.3878 0.8658
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0013 0.0004 0.001
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0012 0.0099
Echinococcus granulosus somatostatin receptor 0.081 0.4478 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Loa Loa (eye worm) neuropeptide F receptor 0.081 0.4478 1
Echinococcus multilocularis somatostatin receptor 0.081 0.4478 0.4476
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.081 0.4478 0.4476
Trypanosoma brucei unspecified product 0.0028 0.0085 0.0699
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0422 0.0943
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0132 0.0294
Mycobacterium tuberculosis Probable conserved exported protein 0.0038 0.0145 0.0136
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0175 0.6661
Echinococcus granulosus rhodopsin orphan GPCR 0.081 0.4478 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0175 0.0382
Loa Loa (eye worm) esterase D 0.0038 0.0145 0.0325
Schistosoma mansoni growth hormone secretagogue receptor 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0004 0.0036
Echinococcus granulosus G protein coupled receptor 139 0.081 0.4478 1
Echinococcus granulosus biogenic amine 5HT receptor 0.081 0.4478 1
Leishmania major hypothetical protein, conserved 0.023 0.1219 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0132 0.1081
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Echinococcus granulosus sex peptide receptor 0.081 0.4478 1
Echinococcus multilocularis dna polymerase eta 0.0066 0.0299 0.0295
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.02 0.1645
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0473 0.1057
Entamoeba histolytica endo-1,4-beta-xylanase, putative 0.0038 0.0145 0.1364
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Echinococcus multilocularis S formylglutathione hydrolase 0.0038 0.0145 0.0141
Echinococcus multilocularis dro:myosuppressin receptor 0.081 0.4478 0.4476
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni ap endonuclease 0.0042 0.0166 0.037
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0012 0.0074
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.081 0.4478 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0012 0.0074
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0034 0.1279
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0132 0.0268
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0013 0.0004 0.0166
Echinococcus granulosus neuropeptide receptor 0.081 0.4478 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0146 0.0316
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0113 0.0925
Mycobacterium ulcerans secreted Mpt51/Mpb51 antigen protein FbpD 0.0038 0.0145 0.0291
Trypanosoma brucei hypothetical protein, conserved 0.023 0.1219 1
Onchocerca volvulus 0.081 0.4478 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.015 0.1405
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0634 0.3486 0.7785
Echinococcus granulosus fmrfamide receptor 0.081 0.4478 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.015 0.1405
Trypanosoma cruzi hypothetical protein, conserved 0.023 0.1219 1
Schistosoma mansoni neuropeptide receptor 0.081 0.4478 1
Loa Loa (eye worm) pip kinase 1 0.0013 0.0004 0.001
Onchocerca volvulus 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0155 0.1271
Echinococcus granulosus serotonin receptor 0.081 0.4478 1
Schistosoma mansoni opsin-like receptor 0.081 0.4478 1
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0155 0.031
Brugia malayi hypothetical protein 0.081 0.4478 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0132 0.0294
Brugia malayi hypothetical protein 0.0026 0.0079 0.0176
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0079 0.0158
Schistosoma mansoni rotamase 0.0033 0.0117 0.0262
Echinococcus granulosus pyruvate kinase 0.0036 0.0132 0.0285
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0155 0.0151
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0175 0.144
Schistosoma mansoni pyruvate kinase 0.0036 0.0132 0.0294
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1038 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0079 0.0646
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.081 0.4478 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.081 0.4478 1
Giardia lamblia DINP protein human, muc B family 0.004 0.0155 0.1491
Echinococcus granulosus snurportin 1 0.0634 0.3486 0.7782
Brugia malayi Serotonin receptor 0.081 0.4478 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0132 0.1081
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0155 0.1271
Schistosoma mansoni hypothetical protein 0.0102 0.0503 0.1123
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0012 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1038 1
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0132 0.1081
Mycobacterium ulcerans hypothetical protein 0.0038 0.0145 0.0291
Echinococcus granulosus neuropeptides capa receptor 0.081 0.4478 1
Schistosoma mansoni opsin-like receptor 0.081 0.4478 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0166 0.136
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.081 0.4478 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.081 0.4478 1
Echinococcus granulosus pyruvate kinase 0.0018 0.0034 0.0066
Echinococcus granulosus neuropeptide s receptor 0.081 0.4478 1
Trypanosoma cruzi hypothetical protein, conserved 0.023 0.1219 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0176 0.0919 0.0915
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0004 0.0166
Plasmodium falciparum pyruvate kinase 0.0036 0.0132 0.5
Onchocerca volvulus 0.081 0.4478 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0166 0.629
Mycobacterium ulcerans secreted antigen 85-B FbpB 0.0038 0.0145 0.0291
Echinococcus multilocularis neuropeptide Y receptor 0.081 0.4478 0.4476
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Echinococcus multilocularis muscleblind protein 0.0171 0.089 0.0886
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.081 0.4478 1
Brugia malayi hypothetical protein 0.081 0.4478 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.081 0.4478 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0176 0.0919 0.0915
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0479 0.4589
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0013 0.0004 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0155 0.1271
Onchocerca volvulus 0.081 0.4478 1
Schistosoma mansoni hypothetical protein 0.0703 0.3878 0.8658
Mycobacterium tuberculosis Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-bind 0.0038 0.0145 0.0136
Echinococcus granulosus geminin 0.0703 0.3878 0.8657
Echinococcus granulosus rhodopsin orphan GPCR 0.081 0.4478 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Schistosoma mansoni hypothetical protein 0.081 0.4478 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Mycobacterium ulcerans hypothetical protein 0.0026 0.0079 0.0158
Entamoeba histolytica hypothetical protein 0.0038 0.0146 0.1367
Loa Loa (eye worm) TYRA-2 protein 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0004 0.0036
Onchocerca volvulus 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0071 0.0158
Brugia malayi RNA, U transporter 1 0.0169 0.0878 0.196
Trichomonas vaginalis importin beta-1, putative 0.0048 0.02 0.1896
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0079 0.0158
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0175 0.6661
Onchocerca volvulus 0.081 0.4478 1
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0166 0.156
Onchocerca volvulus 0.081 0.4478 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0132 0.0294
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0071 0.0642
Echinococcus granulosus neuropeptide Y receptor 0.081 0.4478 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0166 0.136
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0079 0.299
Schistosoma mansoni myosin xvIII 0.081 0.4478 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0004 0.0036
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0012 0.0099
Mycobacterium leprae SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) 0.0902 0.4994 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Brugia malayi Dopamine receptor protein 1 0.081 0.4478 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.081 0.4478 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.081 0.4478 0.4476
Leishmania major GTP-binding protein, putative 0.0044 0.0175 0.144
Echinococcus granulosus biogenic amine 5HT receptor 0.081 0.4478 1
Brugia malayi AKH receptor 0.081 0.4478 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.015 0.1405
Echinococcus multilocularis neuropeptide receptor A26 0.081 0.4478 0.4476
Schistosoma mansoni amine GPCR 0.081 0.4478 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0197 0.1038 1
Schistosoma mansoni alpha glucosidase 0.0039 0.015 0.0334
Echinococcus granulosus 7tm_1 domain containing protein 0.081 0.4478 1
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0164 0.0853 0.1896
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0166 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.015 0.1228
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0117 0.1091
Loa Loa (eye worm) hypothetical protein 0.0171 0.089 0.1987
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0166 0.037
Echinococcus granulosus expressed protein 0.0033 0.0117 0.0252
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.015 0.1405
Schistosoma mansoni amine GPCR 0.081 0.4478 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Onchocerca volvulus 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.081 0.4478 0.4476
Echinococcus granulosus tm gpcr rhodopsin 0.081 0.4478 1
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.1038 0.2319
Echinococcus granulosus pyruvate kinase 0.0036 0.0132 0.0285
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.081 0.4478 0.4476
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0166 0.156
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0164 0.0853 0.1904
Schistosoma mansoni hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.0422 0.4042
Echinococcus multilocularis g protein coupled receptor 0.081 0.4478 0.4476
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0166 0.156
Echinococcus multilocularis G protein coupled receptor 139 0.081 0.4478 0.4476
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.081 0.4478 1
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0079 0.0166
Echinococcus multilocularis pyruvate kinase 0.0028 0.0089 0.0085
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.1038 0.8522
Onchocerca volvulus 0.081 0.4478 1
Echinococcus granulosus rhodopsin orphan GPCR 0.081 0.4478 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.081 0.4478 1
Brugia malayi Esterase D 0.0038 0.0145 0.0325
Echinococcus granulosus S formylglutathione hydrolase 0.0038 0.0145 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.081 0.4478 1
Brugia malayi G-protein coupled receptor 0.081 0.4478 1
Schistosoma mansoni ran 0.0044 0.0175 0.0392
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0197 0.1038 0.1035
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0013 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0012 0.0074
Echinococcus multilocularis fmrfamide receptor 0.081 0.4478 0.4476
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Brugia malayi GnHR receptor homolog 0.081 0.4478 1
Schistosoma mansoni neuropeptide receptor 0.081 0.4478 1
Plasmodium falciparum importin beta, putative 0.0059 0.0263 1
Brugia malayi hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) G-protein coupled receptor 0.081 0.4478 1
Plasmodium vivax importin-beta 2, putative 0.0059 0.0263 1
Echinococcus granulosus orexin receptor type 2 0.081 0.4478 1
Echinococcus granulosus importin subunit beta 1 0.0059 0.0263 0.0579
Trichomonas vaginalis rotamase, putative 0.0033 0.0117 0.1091
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0155 0.1271
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0263 0.0259
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0175 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0166 0.629
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0013 0.0004 0.0166
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.0422 0.4042
Echinococcus granulosus rhodopsin orphan GPCR 0.081 0.4478 1
Onchocerca volvulus 0.0164 0.0853 0.1883
Onchocerca volvulus 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0079 0.0176
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0113 0.1048
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0013 0.0004 0.0166
Brugia malayi hypothetical protein 0.081 0.4478 1
Schistosoma mansoni adenoreceptor 0.081 0.4478 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0166 0.0177
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0155 0.0346
Echinococcus granulosus lysosomal alpha glucosidase 0.0176 0.0919 0.2044
Loa Loa (eye worm) hypothetical protein 0.0171 0.089 0.1987
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Echinococcus multilocularis g protein coupled receptor 0.081 0.4478 0.4476
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.081 0.4478 0.4476
Trypanosoma brucei unspecified product 0.004 0.0155 0.1271
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Echinococcus multilocularis serotonin receptor 0.081 0.4478 0.4476
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.015 0.1405
Echinococcus multilocularis fmrfamide receptor 0.081 0.4478 0.4476
Giardia lamblia Hypothetical protein 0.0013 0.0004 0.0042
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0132 0.0294
Echinococcus multilocularis sex peptide receptor 0.081 0.4478 0.4476
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0166 0.136
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0004 0.0042
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0166 0.136
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.081 0.4478 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.081 0.4478 0.4476
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.1038 1
Brugia malayi hypothetical protein 0.081 0.4478 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0012 0.0074
Echinococcus multilocularis pyruvate kinase 0.0018 0.0034 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0473 0.1057
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Brugia malayi Glycosyl hydrolases family 31 protein 0.0176 0.0919 0.2051
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0155 0.0346
Echinococcus multilocularis expressed protein 0.0033 0.0117 0.0113
Brugia malayi ImpB/MucB/SamB family protein 0.0066 0.0299 0.0669
Leishmania major DNA polymerase eta, putative 0.0038 0.0145 0.1186
Brugia malayi putative neuropeptide receptor NPR1 0.081 0.4478 1
Echinococcus multilocularis muscleblind protein 1 0.0171 0.089 0.0886
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.081 0.4478 1
Schistosoma mansoni alpha-glucosidase 0.0152 0.0781 0.1744
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.081 0.4478 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.081 0.4478 1
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0038 0.0145 0.0136
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0113 0.0925
Brugia malayi Dopamine receptor protein 2 0.081 0.4478 1
Brugia malayi sulfakinin receptor protein 0.081 0.4478 1
Brugia malayi neuropeptide F receptor 0.081 0.4478 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0175 0.144
Echinococcus multilocularis neuropeptides capa receptor 0.081 0.4478 0.4476
Echinococcus multilocularis neuropeptide receptor 0.081 0.4478 0.4476
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0175 0.144
Echinococcus multilocularis survival motor neuron protein 1 0.05 0.2739 0.2735
Schistosoma mansoni hypothetical protein 0.081 0.4478 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0155 0.1271
Mycobacterium tuberculosis Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) 0.0902 0.4994 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0012 0.0074
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.081 0.4478 1
Echinococcus granulosus g-protein coupled receptor 0.081 0.4478 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0085 0.0699
Schistosoma mansoni biogenic amine receptor 0.081 0.4478 1
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0155 0.031
Mycobacterium ulcerans hypothetical protein 0.0026 0.0079 0.0158
Brugia malayi follicle stimulating hormone receptor 0.081 0.4478 1
Echinococcus granulosus g protein coupled receptor 0.081 0.4478 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.081 0.4478 0.4476
Onchocerca volvulus 0.0102 0.0502 0.1097
Schistosoma mansoni opsin-like receptor 0.081 0.4478 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0132 0.0108
Onchocerca volvulus 0.081 0.4478 1
Schistosoma mansoni hypothetical protein 0.081 0.4478 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0473 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.081 0.4478 1
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.081 0.4478 1
Leishmania major importin beta-1 subunit, putative 0.0048 0.02 0.1645
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0155 0.1271
Mycobacterium leprae Secreted antigen 85A FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0038 0.0145 0.0028
Echinococcus multilocularis G-protein coupled receptor, putative 0.081 0.4478 0.4476
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0473 0.1057
Brugia malayi RE15519p 0.081 0.4478 1
Echinococcus granulosus survival motor neuron protein 1 0.05 0.2739 0.6111
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.015 0.5681
Echinococcus granulosus hypothetical protein 0.081 0.4478 1
Mycobacterium ulcerans hypothetical protein 0.0038 0.0145 0.0291
Loa Loa (eye worm) hypothetical protein 0.081 0.4478 1
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0132 0.0294
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0197 0.1038 0.2319
Schistosoma mansoni rhodopsin-like orphan GPCR 0.081 0.4478 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0117 0.0262
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.081 0.4478 0.4476
Brugia malayi G protein-coupled receptor 0.081 0.4478 1
Giardia lamblia Kinase, PLK 0.0197 0.1038 1
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0166 0.037
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0079 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0085 0.0699
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0132 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.081 0.4478 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.015 0.1405
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0164 0.0853 0.1904
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.081 0.4478 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.015 0.1405
Echinococcus granulosus thyrotropin releasing hormone receptor 0.081 0.4478 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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