Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0102 | 0.164 | 0.2697 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0505 | 1 | 1 |
Echinococcus granulosus | elongation of very long chain fatty acids | 0.0102 | 0.164 | 0.2697 |
Schistosoma mansoni | hypothetical protein | 0.0302 | 0.5782 | 1 |
Brugia malayi | fatty acid elongation protein 3 | 0.0102 | 0.164 | 0.1547 |
Trypanosoma brucei | Fatty acid elongase | 0.0102 | 0.164 | 0.1547 |
Onchocerca volvulus | Elongation of very long chain fatty acids protein homolog | 0.0102 | 0.164 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0257 | 0.0257 |
Toxoplasma gondii | integral membrane protein, GNS1/SUR4 family protein, putative | 0.0505 | 1 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0257 | 1 |
Brugia malayi | Hypothetical 34.1 kDa protein C40H1.4 in chromosome III | 0.0102 | 0.164 | 0.1547 |
Plasmodium vivax | elongation of very long chain fatty acids protein 3, putative | 0.0102 | 0.164 | 0.1547 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0257 | 0.0147 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Onchocerca volvulus | Elongation of very long chain fatty acids protein 5 homolog | 0.0102 | 0.164 | 1 |
Trypanosoma brucei | elongation of very long chain fatty acids protein, putative | 0.0102 | 0.164 | 0.1547 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0257 | 0.0147 |
Brugia malayi | fatty acid elongation protein 3 | 0.0102 | 0.164 | 0.1547 |
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0102 | 0.164 | 0.2697 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.0147 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0207 | 0.3826 | 0.655 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Brugia malayi | fatty acid elongation protein 3 | 0.0102 | 0.164 | 0.1547 |
Brugia malayi | GNS1/SUR4 family protein | 0.0102 | 0.164 | 0.1547 |
Plasmodium falciparum | long chain polyunsaturated fatty acid elongation enzyme, putative | 0.0102 | 0.164 | 0.1547 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Trypanosoma brucei | Fatty acid elongase | 0.0102 | 0.164 | 0.1547 |
Echinococcus granulosus | snurportin 1 | 0.0302 | 0.5782 | 1 |
Leishmania major | fatty acid elongase, putative | 0.0505 | 1 | 1 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0505 | 1 | 1 |
Plasmodium vivax | long chain polyunsaturated fatty acid elongation enzyme, putative | 0.0102 | 0.164 | 0.1547 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0257 | 0.0257 |
Plasmodium falciparum | long chain fatty acid elongation enzyme, putative | 0.0505 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0257 | 1 |
Onchocerca volvulus | Elongation of very long chain fatty acids protein homolog | 0.0102 | 0.164 | 1 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Onchocerca volvulus | 0.0102 | 0.164 | 1 | |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Leishmania major | fatty acid elongase, putative | 0.0505 | 1 | 1 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0207 | 0.3826 | 0.655 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0257 | 0.5 |
Brugia malayi | fatty acid elongation protein 3 | 0.0102 | 0.164 | 0.1547 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0257 | 0.0147 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Echinococcus granulosus | elongation of very long chain fatty acids | 0.0102 | 0.164 | 0.2697 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0257 | 0.0257 |
Loa Loa (eye worm) | GNS1/SUR4 family protein | 0.0505 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.164 | 0.1547 |
Schistosoma mansoni | fatty acid acyl transferase-related | 0.0102 | 0.164 | 0.2697 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0257 | 0.0147 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0257 | 0.0147 |
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0102 | 0.164 | 0.2697 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.0147 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0257 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0257 | 0.0257 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0102 | 0.164 | 0.1547 |
Echinococcus multilocularis | elongation of very long chain fatty acids | 0.0102 | 0.164 | 0.2697 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0257 | 1 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0302 | 0.5782 | 0.5735 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.0147 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0257 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0257 | 0.5 |
Loa Loa (eye worm) | GNS1/SUR4 family protein | 0.0102 | 0.164 | 0.1547 |
Onchocerca volvulus | 0.0102 | 0.164 | 1 | |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0505 | 1 | 1 |
Plasmodium falciparum | fatty acid elongation protein, GNS1/SUR4 family, putative | 0.0505 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.0147 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0257 | 1 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0257 | 0.5 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0505 | 1 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0257 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0257 | 0.0257 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0257 | 0.0147 |
Plasmodium vivax | GNS1/SUR4 domain containing protein | 0.0505 | 1 | 1 |
Toxoplasma gondii | GNS1/SUR4 family protein | 0.0505 | 1 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0226 | 0.4201 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.3826 | 0.3757 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0257 | 0.0257 |
Leishmania major | long chain polyunsaturated fatty acid elongation enzyme-like protein | 0.0102 | 0.164 | 0.164 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0257 | 0.0147 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0257 | 0.5 |
Leishmania major | fatty acid elongase, putative | 0.0505 | 1 | 1 |
Trypanosoma brucei | Long chain fatty acyl elongase | 0.0102 | 0.164 | 0.1547 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0257 | 0.5 |
Echinococcus multilocularis | hormone sensitive lipase | 0.0207 | 0.3826 | 0.655 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.0147 |
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0102 | 0.164 | 0.2697 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0257 | 0.5 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0102 | 0.164 | 0.1547 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0207 | 0.3826 | 0.655 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0505 | 1 | 1 |
Echinococcus multilocularis | elongation of very long chain fatty acids | 0.0102 | 0.164 | 0.2697 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0257 | 0.0257 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0102 | 0.164 | 0.1547 |
Brugia malayi | GNS1/SUR4 family protein | 0.0505 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.0147 |
Loa Loa (eye worm) | ELO-9 protein | 0.0102 | 0.164 | 0.1547 |
Echinococcus granulosus | hormone sensitive lipase | 0.0207 | 0.3826 | 0.655 |
Toxoplasma gondii | fatty acid elongase | 0.0102 | 0.164 | 0.1547 |
Trypanosoma brucei | Fatty acid elongase | 0.0505 | 1 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0257 | 0.0147 |
Echinococcus multilocularis | snurportin 1 | 0.0302 | 0.5782 | 1 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Leishmania major | fatty acid elongase, putative | 0.0102 | 0.164 | 0.164 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.1192 | 0.1093 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0257 | 0.0147 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.