Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0193 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.