Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0472 | 0.0521 |
Echinococcus granulosus | caspase 3 | 0.0071 | 0.1975 | 0.2225 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0472 | 0.0697 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0115 | 0.3266 | 0.3688 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.0185 | 0.0197 |
Echinococcus multilocularis | chromobox protein 2 | 0.0011 | 0.0185 | 0.0197 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Echinococcus granulosus | nibrin | 0.001 | 0.014 | 0.0145 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.001 | 0.0162 | 0.0616 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0142 | 0.0147 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.014 | 0.0145 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.001 | 0.0162 | 0.0616 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0931 | 0.4902 |
Echinococcus granulosus | dual specificity | 0.0087 | 0.2458 | 0.2771 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0043 | 0.1144 | 0.4331 |
Trypanosoma cruzi | metacaspase, putative | 0.0043 | 0.1144 | 0.4331 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1886 | 0.2124 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0185 | 0.0263 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.001 | 0.0162 | 0.0285 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.1144 | 0.6039 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0227 | 0.1148 |
Brugia malayi | hypothetical protein | 0.001 | 0.014 | 0.0194 |
Leishmania major | cytochrome p450-like protein | 0.001 | 0.0162 | 0.0616 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0084 | 0.2346 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0162 | 0.0228 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0011 | 0.0185 | 0.0197 |
Echinococcus multilocularis | caspase | 0.0115 | 0.3266 | 0.3688 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0818 | 1 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0115 | 0.3266 | 0.3696 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.001 | 0.0162 | 0.0285 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.009 | 0.0089 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0115 | 0.3266 | 0.3696 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.001 | 0.0162 | 0.0285 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0301 | 0.8838 | 1 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.009 | 0.0089 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0043 | 0.1144 | 0.4331 |
Entamoeba histolytica | protein kinase, putative | 0.0087 | 0.2458 | 0.2458 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.3337 | 0.3768 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.0185 | 0.021 |
Echinococcus multilocularis | snurportin 1 | 0.0301 | 0.8838 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.001 | 0.0162 | 0.0332 |
Schistosoma mansoni | topbp1 | 0.001 | 0.014 | 0.0158 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.2246 | 0.3385 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0931 | 0.1041 |
Schistosoma mansoni | DNA ligase IV | 0.001 | 0.014 | 0.0158 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1886 | 0.2124 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0142 | 0.0147 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.009 | 0.0102 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0043 | 0.1144 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0087 | 0.2458 | 0.2458 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0694 | 0.6029 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0472 | 0.1882 |
Echinococcus granulosus | smad | 0.0008 | 0.009 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.2444 | 0.2756 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0005 | 0.0012 | 0.0103 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.1144 | 0.6039 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.009 | 0.0102 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0535 | 0.1705 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0931 | 0.8137 |
Echinococcus granulosus | chromobox protein 2 | 0.0011 | 0.0185 | 0.0197 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.014 | 0.0684 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0142 | 0.0147 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.009 | 0.0089 |
Toxoplasma gondii | chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 | 0.0011 | 0.0185 | 0.1621 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0162 | 0.0184 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0142 | 0.0197 |
Trichomonas vaginalis | hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Mycobacterium leprae | Conserved hypothetical protein | 0.001 | 0.0162 | 0.0332 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0084 | 0.2346 | 0.2655 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0087 | 0.2458 | 1 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.0185 | 0.021 |
Echinococcus multilocularis | caspase 8 | 0.0043 | 0.1144 | 0.1283 |
Trypanosoma brucei | metacaspase MCA2 | 0.0043 | 0.1144 | 0.4628 |
Trypanosoma cruzi | cytochrome P450, putative | 0.001 | 0.0162 | 0.0097 |
Leishmania major | metacaspase, putative | 0.0043 | 0.1144 | 0.4628 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.009 | 0.0102 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0011 | 0.0185 | 0.0263 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.009 | 0.0119 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.004 | 0.1055 | 0.1182 |
Schistosoma mansoni | importin-beta 2 | 0.0005 | 0.0012 | 0.0013 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0342 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0535 | 0.0535 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.0185 | 0.021 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.001 | 0.0162 | 0.0285 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.3337 | 0.3768 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0931 | 0.1053 |
Trypanosoma brucei | metacaspase | 0.0043 | 0.1144 | 0.4628 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Echinococcus multilocularis | smad | 0.0008 | 0.009 | 0.0089 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.001 | 0.0162 | 0.0285 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0005 | 0.0012 | 0.0103 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0314 | 0.1235 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0694 | 0.1034 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0087 | 0.2458 | 0.2781 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.3337 | 0.5038 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.014 | 0.0684 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0011 | 0.0185 | 0.0263 |
Brugia malayi | follicle stimulating hormone receptor | 0.0227 | 0.6613 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0142 | 0.0147 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0227 | 0.088 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0314 | 0.0342 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.014 | 0.0145 |
Trypanosoma brucei | cytochrome P450, putative | 0.001 | 0.0162 | 0.0616 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0355 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0142 | 0.0147 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.066 | 0.3457 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.001 | 0.014 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.2444 | 0.2756 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.009 | 0.0089 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0472 | 0.4127 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0818 | 1 |
Brugia malayi | topoisomerase | 0.001 | 0.014 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.2346 | 0.2645 |
Echinococcus multilocularis | nibrin | 0.001 | 0.014 | 0.0145 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.014 | 0.0145 |
Treponema pallidum | DNA ligase (lig) | 0.001 | 0.014 | 0.5 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.014 | 0.0684 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0931 | 0.1041 |
Brugia malayi | Protein cec-1. | 0.0011 | 0.0185 | 0.0263 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0694 | 0.6029 |
Leishmania major | cytochrome p450-like protein | 0.001 | 0.0162 | 0.0616 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0472 | 0.1433 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.014 | 0.0684 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.014 | 0.0524 |
Trypanosoma brucei | metacaspase MCA3 | 0.0043 | 0.1144 | 0.4628 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0342 |
Brugia malayi | Smad1 | 0.0008 | 0.009 | 0.0119 |
Trypanosoma cruzi | cytochrome P450, putative | 0.001 | 0.0162 | 0.0097 |
Echinococcus granulosus | caspase 8 | 0.0043 | 0.1144 | 0.1283 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.009 | 0.0102 |
Onchocerca volvulus | 0.004 | 0.1055 | 0.4148 | |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Echinococcus multilocularis | caspase 3 | 0.0071 | 0.1975 | 0.2225 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.001 | 0.0162 | 0.0171 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.001 | 0.0162 | 0.0285 |
Trypanosoma brucei | metacaspase 5, putative | 0.0043 | 0.1144 | 0.4628 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.1144 | 0.6039 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.001 | 0.0162 | 0.0285 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0993 | 0.5232 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0142 | 0.124 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0015 | 0.0314 | 0.1235 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0321 | 0.2804 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.001 | 0.0162 | 0.0285 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0011 | 0.0185 | 0.0197 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1886 | 0.2134 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0746 | 0.0832 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0015 | 0.0314 | 0.2309 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.8838 | 1 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0472 | 0.0472 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0993 | 0.1486 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.001 | 0.014 | 0.1223 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1055 | 0.1182 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.001 | 0.0162 | 0.0285 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.0185 | 0.021 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.1079 | 0.4257 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0043 | 0.1144 | 0.1294 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0931 | 0.1392 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.001 | 0.0162 | 0.0285 |
Entamoeba histolytica | hypothetical protein | 0.0097 | 0.274 | 0.274 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0142 | 0.016 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.0185 | 0.021 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0011 | 0.0185 | 0.1621 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0115 | 0.3266 | 0.3688 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0472 | 0.4066 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Trypanosoma cruzi | metacaspase, putative | 0.0043 | 0.1144 | 0.4331 |
Plasmodium falciparum | chromodomain-helicase-DNA-binding protein 1 homolog, putative | 0.0011 | 0.0185 | 0.1534 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.014 | 0.0684 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.014 | 0.0684 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0694 | 0.0773 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0694 | 0.607 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.001 | 0.0162 | 0.0285 |
Schistosoma mansoni | smad | 0.0008 | 0.009 | 0.0102 |
Schistosoma mansoni | ran | 0.0021 | 0.0472 | 0.0534 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0931 | 0.3757 |
Brugia malayi | cytochrome P450 | 0.001 | 0.0162 | 0.0228 |
Echinococcus granulosus | Chromo domain | 0.0011 | 0.0185 | 0.0197 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Echinococcus granulosus | Chromobox protein 3 | 0.0011 | 0.0185 | 0.0197 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0553 | 0.2889 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1886 | 1 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.001 | 0.0162 | 0.0285 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0185 | 0.0185 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.0185 | 0.0197 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0142 | 0.0197 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0227 | 0.0227 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0535 | 0.2792 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.001 | 0.0162 | 0.0097 |
Echinococcus granulosus | caspase 2 | 0.0084 | 0.2346 | 0.2645 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0719 | 0.1072 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.338 | 0.3816 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0043 | 0.1144 | 0.1715 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0185 | 0.0185 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0472 | 0.4066 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0535 | 0.2792 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0694 | 0.0786 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0472 | 0.2455 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0011 | 0.0185 | 0.1621 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1886 | 0.2124 |
Loa Loa (eye worm) | CYP4Cod1 | 0.001 | 0.0162 | 0.0171 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0468 | 0.4032 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0314 | 0.075 |
Entamoeba histolytica | Rad52/22 family double-strand break repair protein, putative | 0.0097 | 0.274 | 0.274 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.1144 | 0.6039 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0342 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0457 |
Trypanosoma cruzi | metacaspase, putative | 0.0043 | 0.1144 | 0.4331 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0326 | 0.2779 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0142 | 0.0002 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0472 | 0.1882 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0087 | 0.2458 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0553 | 0.082 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0185 | 0.021 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0931 | 0.3757 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0931 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.009 | 0.0119 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0535 | 0.2139 |
Entamoeba histolytica | protein kinase, putative | 0.0087 | 0.2458 | 0.2458 |
Plasmodium falciparum | metacaspase-like protein | 0.0043 | 0.1144 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.009 | 0.0089 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.001 | 0.0162 | 0.0171 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0011 | 0.0185 | 0.021 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0043 | 0.1144 | 1 |
Plasmodium falciparum | heterochromatin protein 1 | 0.0011 | 0.0185 | 0.1534 |
Echinococcus multilocularis | caspase 2 | 0.0084 | 0.2346 | 0.2645 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.001 | 0.0162 | 0.0285 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0472 | 0.0521 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.1886 | 0.284 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.001 | 0.0162 | 0.0097 |
Onchocerca volvulus | 0.0011 | 0.0185 | 0.0206 | |
Brugia malayi | hypothetical protein | 0.001 | 0.014 | 0.0194 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.014 | 0.0145 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0472 | 0.0337 |
Onchocerca volvulus | 0.0011 | 0.0185 | 0.0206 | |
Echinococcus multilocularis | Chromo domain | 0.0011 | 0.0185 | 0.0197 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.001 | 0.014 | 0.0194 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0342 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.014 | 0.1223 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.001 | 0.014 | 0.1132 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0087 | 0.2458 | 0.2771 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.0185 | 0.0926 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0142 | 0.016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.1144 | 0.6039 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0931 | 0.1053 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0011 | 0.0185 | 0.1534 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.066 | 0.3457 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0535 | 0.2792 |
Brugia malayi | Valyl-tRNA synthetase | 0.0011 | 0.0185 | 0.0263 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.009 | 0.0119 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.014 | 0.0145 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0931 | 0.3412 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0185 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0931 | 0.1041 |
Chlamydia trachomatis | DNA ligase | 0.001 | 0.014 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.001 | 0.014 | 0.014 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0472 | 0.1433 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0457 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.001 | 0.0162 | 0.0171 |
Trichomonas vaginalis | Heterochromatin protein, putative | 0.0011 | 0.0185 | 0.0926 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0185 | 0.0197 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.001 | 0.0162 | 0.0285 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0043 | 0.1144 | 1 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.001 | 0.0142 | 0.1149 |
Brugia malayi | CHD4 protein | 0.0011 | 0.0185 | 0.0263 |
Loa Loa (eye worm) | helicase | 0.0011 | 0.0185 | 0.0197 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0011 | 0.0185 | 0.0263 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0142 | 0.0147 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1079 | 0.5694 |
Plasmodium vivax | heterochromatin protein 1, putative | 0.0011 | 0.0185 | 0.1534 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0227 | 0.0375 |
Onchocerca volvulus | 0.003 | 0.0746 | 0.2748 | |
Schistosoma mansoni | topbp1 | 0.001 | 0.014 | 0.0158 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0931 | 0.4902 |
Echinococcus granulosus | snurportin 1 | 0.0301 | 0.8838 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0227 | 0.6613 | 0.748 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.014 | 0.0684 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1886 | 0.2124 |
Loa Loa (eye worm) | cytochrome P450 | 0.001 | 0.0162 | 0.0171 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.0185 | 0.1534 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0472 | 0.0521 |
Entamoeba histolytica | hypothetical protein | 0.0087 | 0.2458 | 0.2458 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0553 | 0.0614 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.014 | 0.0684 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0142 | 0.124 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.0185 | 0.0197 |
Leishmania major | cytochrome p450-like protein | 0.001 | 0.0162 | 0.0616 |
Brugia malayi | Protein kinase domain containing protein | 0.0087 | 0.2458 | 0.3705 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0553 | 0.0614 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.014 | 0.0145 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.001 | 0.0162 | 0.0285 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1886 | 1 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.014 | 0.0158 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.1144 | 1 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.001 | 0.0162 | 0.142 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0087 | 0.2458 | 1 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.004 | 0.1055 | 0.1182 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0185 | 0.0197 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.0185 | 0.0926 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.0185 | 0.1534 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.001 | 0.0162 | 0.0285 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.014 | 0.0684 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0314 | 0.075 |
Echinococcus granulosus | caspase | 0.0115 | 0.3266 | 0.3688 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.009 | 0.0102 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.009 | 0.0119 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0931 | 0.4902 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0694 | 0.0773 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0694 | 0.279 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0043 | 0.1144 | 0.6039 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0227 | 0.088 |
Schistosoma mansoni | cytochrome P450 | 0.001 | 0.0162 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0185 | 0.0197 |
Echinococcus multilocularis | dual specificity | 0.0087 | 0.2458 | 0.2771 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0162 | 0.0228 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0694 | 0.0773 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0162 | 0.0228 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0185 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0993 | 0.3864 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.1886 | 0.2124 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.001 | 0.0162 | 0.0285 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.001 | 0.014 | 0.1132 |
Echinococcus multilocularis | 0.001 | 0.0162 | 0.0171 | |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.014 | 0.014 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0015 | 0.0314 | 0.2668 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0185 | 0.0926 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0185 | 0.0185 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0185 | 0.0926 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0342 |
Plasmodium falciparum | metacaspase 1 | 0.0043 | 0.1144 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.009 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0993 | 0.1111 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.009 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.1055 | 0.1194 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.009 | 0.0089 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0993 | 0.5232 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0553 | 0.0614 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0185 | 0.0197 |
Trypanosoma brucei | ULK family serine/threonine-protein kinase, putative | 0.0006 | 0.0025 | 0.0055 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0015 | 0.0314 | 0.2668 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1079 | 0.5694 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0185 | 0.0197 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.001 | 0.0162 | 0.0285 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.0185 | 0.0197 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0931 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.009 | 0.0089 |
Plasmodium vivax | metacaspase 1, putative | 0.0043 | 0.1144 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.2743 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1144 | 0.1283 |
Giardia lamblia | DNA repair protein RAD52 | 0.034 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0719 | 0.0802 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.0342 |
Trypanosoma brucei | Metacaspase-4 | 0.0043 | 0.1144 | 0.4628 |
Brugia malayi | Cell death protein 3 precursor | 0.0084 | 0.2346 | 0.3537 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0553 | 0.2889 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0694 | 0.279 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1886 | 0.2134 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.0185 | 0.021 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.001 | 0.0162 | 0.0285 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0087 | 0.2458 | 1 |
Trypanosoma cruzi | metacaspase, putative | 0.0043 | 0.1144 | 0.4331 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0931 | 0.3412 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0185 | 0.0197 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.001 | 0.0162 | 0.0285 |
Brugia malayi | DKFZp564C0469 protein | 0.001 | 0.014 | 0.0194 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.001 | 0.0162 | 0.0097 |
Brugia malayi | hypothetical protein | 0.004 | 0.1055 | 0.1581 |
Brugia malayi | SET domain containing protein | 0.0011 | 0.0185 | 0.0263 |
Onchocerca volvulus | 0.0011 | 0.0185 | 0.0206 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.1144 | 0.6039 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.014 | 0.0145 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.001 | 0.0162 | 0.0285 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0314 | 0.2743 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.014 | 0.0145 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0406 | 0.0459 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0314 | 0.1235 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.0185 | 0.0926 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0185 | 0.0197 |
Entamoeba histolytica | HEAT repeat domain containing protein | 0.0005 | 0.0012 | 0.0012 |
Schistosoma mansoni | ran | 0.0021 | 0.0472 | 0.0534 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0931 | 0.0931 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.014 | 0.0684 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.