Detailed information for compound 916928

Basic information

Technical information
  • TDR Targets ID: 916928
  • Name: (2R,3R,4S)-2-(6-aminopurin-9-yl)-4-(hydroxyme thyl)oxolan-3-ol
  • MW: 251.242 | Formula: C10H13N5O3
  • H donors: 3 H acceptors: 5 LogP: -1.1 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1CO[C@H]([C@@H]1O)n1cnc2c1ncnc2N
  • InChi: 1S/C10H13N5O3/c11-8-6-9(13-3-12-8)15(4-14-6)10-7(17)5(1-16)2-18-10/h3-5,7,10,16-17H,1-2H2,(H2,11,12,13)/t5-,7+,10+/m0/s1
  • InChiKey: KQLDDLUWUFBQHP-WVBSTYLSSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3R,4S)-2-(6-aminopurin-9-yl)-4-(hydroxymethyl)tetrahydrofuran-3-ol
  • (2R,3R,4S)-2-(6-amino-9-purinyl)-4-(hydroxymethyl)-3-tetrahydrofuranol
  • (2R,3R,4S)-2-(6-aminopurin-9-yl)-4-methylol-tetrahydrofuran-3-ol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0021 0.0076 0.0075
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0057 0.0381 0.0381
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.018 0.1438 0.1437
Trypanosoma cruzi cysteine protease, putative 0.0608 0.5101 0.5101
Leishmania major cysteine peptidase A (CPA) 0.1181 1 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0475 0.3964 0.3963
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.02 0.0199
Loa Loa (eye worm) sirtuin 4 0.0198 0.1594 0.1594
Loa Loa (eye worm) hypothetical protein 0.0098 0.0739 0.0739
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0192 0.0191
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0094 0.0068
Brugia malayi polk-prov protein 0.0018 0.0048 0.0046
Brugia malayi Cathepsin L-like cysteine proteinase 0.079 0.666 0.6659
Brugia malayi transcriptional regulator, Sir2 family protein 0.0198 0.1594 0.1593
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0048 0.0046
Echinococcus granulosus cathepsin L cysteine protease 0.0608 0.5101 0.5101
Loa Loa (eye worm) hypothetical protein 0.0218 0.1761 0.1761
Echinococcus granulosus cathepsin l cysteine peptidase 0.1181 1 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0058 0.0394 0.0393
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0057 0.0056
Loa Loa (eye worm) hypothetical protein 0.0057 0.0381 0.0381
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0218 0.1761 0.176
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0384 0.0498
Schistosoma mansoni kinase 0.0242 0.1964 0.1964
Echinococcus multilocularis cathepsin b 0.0218 0.1761 0.176
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0384 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0058 0.0394 0.0393
Onchocerca volvulus 0.0035 0.0192 0.0117
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0303 0.2491 0.249
Echinococcus granulosus Chromo domain 0.0035 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0018 0.0048 0.0048
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0057 0.0381 0.038
Toxoplasma gondii thioredoxin reductase 0.0228 0.1848 0.1847
Treponema pallidum NADH oxidase 0.0079 0.0573 0.3952
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0029
Schistosoma mansoni phosphoglycerate kinase 0.0168 0.1333 0.1333
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0029 0.0028
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0219 0.0218
Schistosoma mansoni cathepsin s 0.039 0.3237 0.3237
Schistosoma mansoni cathepsin F (C01 family) 0.1181 1 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0034 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0909 0.0908
Giardia lamblia NADH oxidase lateral transfer candidate 0.0079 0.0573 0.0873
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0777 0.6545 0.6545
Echinococcus granulosus cpg binding protein 0.003 0.0153 0.0151
Trichomonas vaginalis apoptosis inducing factor, putative 0.0021 0.0076 0.0075
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0218 0.1761 0.176
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0247 0.0246
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0218 0.1761 0.176
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0076 0.0076
Entamoeba histolytica cysteine protease, putative 0.0218 0.1761 0.176
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0082 0.0599 0.0599
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1181 1 1
Echinococcus granulosus citrate lyase subunit beta protein 0.0073 0.0524 0.0523
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0475 0.3964 0.3963
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0192 0.0191
Brugia malayi PXA domain containing protein 0.0057 0.0381 0.038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0021 0.0076 0.0075
Echinococcus multilocularis dna polymerase kappa 0.0057 0.0384 0.0382
Plasmodium vivax unspecified product 0.039 0.3237 0.3236
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0218 0.1761 0.1761
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0218 0.1761 0.176
Toxoplasma gondii NADPH-glutathione reductase 0.0079 0.0573 0.0571
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0316 0.0315
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Trichomonas vaginalis DNA polymerase eta, putative 0.0057 0.0384 0.0382
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0021 0.0076 0.0075
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0598 0.0597
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0076 0.0075
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0218 0.1761 0.176
Echinococcus granulosus chromobox protein 1 0.0211 0.1703 0.1702
Schistosoma mansoni axis inhibition protein axin 0.0057 0.0381 0.0381
Schistosoma mansoni chromatin regulatory protein sir2 0.0777 0.6545 0.6545
Echinococcus multilocularis jumonji domain containing protein 0.008 0.058 0.0579
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0021 0.0076 0.0042
Mycobacterium tuberculosis Probable reductase 0.052 0.4347 0.8958
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0192 0.0191
Plasmodium falciparum cysteine proteinase falcipain 3 0.1181 1 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0079 0.0573 0.0571
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0449 0.0449
Plasmodium vivax hypothetical protein, conserved 0.0198 0.1594 0.1593
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0381 0.038
Schistosoma mansoni disulfide oxidoreductase 0.0021 0.0076 0.0076
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0005 0.0004
Echinococcus multilocularis cysteine protease 0.1181 1 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0192 0.0191
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0073 0.0524 0.0523
Plasmodium falciparum ferrodoxin reductase-like protein 0.0021 0.0076 0.0075
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0218 0.1761 0.176
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0198 0.1594 0.1593
Onchocerca volvulus Cathepsin L homolog 0.1181 1 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0381 0.0381
Trypanosoma brucei phosphoglycerate kinase, putative 0.0062 0.0424 0.0422
Trichomonas vaginalis CAMK family protein kinase 0.0475 0.3964 0.3963
Brugia malayi cathepsin L-like precursor 0.079 0.666 0.6659
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0073 0.0524 0.0939
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0505 0.0505
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0076 0.0075
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0094 0.0093
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0475 0.3964 0.3964
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0777 0.6545 0.6545
Brugia malayi Papain family cysteine protease containing protein 0.0218 0.1761 0.176
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1181 1 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0082 0.0599 0.0597
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0198 0.1594 0.1593
Brugia malayi Heterochromatin protein 1 0.0211 0.1703 0.1702
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0247 0.0246
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0079 0.0573 0.3952
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Entamoeba histolytica hypothetical protein 0.0035 0.0192 0.0191
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0079 0.0573 0.0779
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0076 0.0075
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0192 0.0191
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.0263 0.0261
Brugia malayi hypothetical protein 0.0057 0.0381 0.038
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0012 0.0001 0.0001
Brugia malayi cathepsin B-like cysteine proteinase 0.0218 0.1761 0.176
Trypanosoma cruzi major cysteine proteinase, putative 0.0218 0.1761 0.176
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0523 0.4375 0.4375
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0057 0.0384 0.0645
Trypanosoma brucei polo-like protein kinase 0.0475 0.3964 0.3963
Echinococcus granulosus Regulator of G protein signaling 20 0.0057 0.0381 0.038
Giardia lamblia Hypothetical protein 0.0777 0.6545 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0192
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0475 0.3964 0.3963
Loa Loa (eye worm) heterochromatin protein 1 0.0211 0.1703 0.1703
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0449 0.0449
Schistosoma mansoni jumonji domain containing protein 0.0149 0.1175 0.1175
Entamoeba histolytica cysteine proteinase, putative 0.0608 0.5101 0.5101
Trichomonas vaginalis chromobox protein, putative 0.0127 0.0986 0.0985
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0021 0.0076 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0608 0.5101 0.5101
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0218 0.1761 0.176
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0048 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0384 0.0382
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0523 0.4375 0.6684
Brugia malayi Protein cec-1. 0.0035 0.0192 0.0191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1181 1 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0523 0.4375 0.4375
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Giardia lamblia Phosphoglycerate kinase 0.0168 0.1333 0.2034
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Trypanosoma brucei unspecified product 0.0057 0.0384 0.0382
Loa Loa (eye worm) fibroinase 0.1181 1 1
Entamoeba histolytica hypothetical protein 0.0035 0.0192 0.0191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Toxoplasma gondii selenide, water dikinase 0.0021 0.0076 0.0075
Brugia malayi Common central domain of tyrosinase family protein 0.018 0.1438 0.1437
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0192 0.0191
Entamoeba histolytica cysteine proteinase, putative 0.0608 0.5101 0.5101
Trichomonas vaginalis glutaminase, putative 0.0805 0.6789 0.6788
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0076 0.0075
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0198 0.1594 0.1593
Entamoeba histolytica disulphide oxidoreductase, putative 0.0021 0.0076 0.0075
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0094 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Entamoeba histolytica cysteine protease, putative 0.0218 0.1761 0.176
Brugia malayi transcriptional regulator, Sir2 family protein 0.0777 0.6545 0.6545
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0409 0.0536
Entamoeba histolytica cysteine proteinase, putative 0.079 0.666 0.6659
Toxoplasma gondii cathepsin CPC1 0.0218 0.1761 0.176
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0394 0.0394
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0079 0.0573 0.0571
Plasmodium vivax NAD-dependent deacetylase, putative 0.0303 0.2491 0.249
Mycobacterium tuberculosis Probable dehydrogenase 0.052 0.4347 0.8958
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1181 1 1
Echinococcus multilocularis cathepsin L 0.0218 0.1761 0.176
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0073 0.0524 0.0706
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0055 0.0054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Giardia lamblia Thioredoxin reductase 0.0021 0.0076 0.0114
Giardia lamblia Transcriptional regulator, Sir2 family 0.0303 0.2491 0.3805
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0316 0.0316
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0218 0.1761 0.1761
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0381 0.038
Trypanosoma cruzi hypothetical protein, conserved 0.0637 0.5344 0.5344
Brugia malayi Papain family cysteine protease containing protein 0.0218 0.1761 0.176
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0381 0.038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0055 0.0054
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0004
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0168 0.1333 0.1331
Brugia malayi Cathepsin L-like precursor 0.1181 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0608 0.5101 0.5101
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0168 0.1333 0.1331
Echinococcus granulosus phosphoglycerate kinase 1 0.0168 0.1333 0.1331
Trypanosoma cruzi cysteine peptidase, putative 0.1181 1 1
Echinococcus granulosus microtubule associated protein 2 0.068 0.5719 0.5719
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0218 0.1761 0.176
Loa Loa (eye worm) cysteine protease 0.1181 1 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0188 0.1506 0.1504
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0021 0.0076 0.0042
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0069 0.0068
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0021 0.0076 0.0075
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0021 0.0076 0.0075
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0048 0.0046
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0777 0.6545 0.6545
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0168 0.1333 0.2635
Entamoeba histolytica cysteine protease, putative 0.0218 0.1761 0.176
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0057 0.0381 0.0381
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0057 0.0384 0.0384
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0454 0.0454
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0218 0.1761 0.176
Giardia lamblia Kinase, PLK 0.0475 0.3964 0.6056
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0079 0.0573 0.3952
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0578 0.4844 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0079 0.0573 0.0571
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0192
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0409 0.0536
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0079 0.0573 0.3952
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0099 0.0098
Brugia malayi serine/threonine-protein kinase plk-2 0.0475 0.3964 0.3963
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0218 0.1761 0.176
Plasmodium falciparum serine repeat antigen 6 0.0218 0.1761 0.176
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0055 0.0054
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0409 0.0409
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0411 0.0411
Mycobacterium ulcerans glutamate synthase subunit beta 0.0021 0.0076 0.0042
Plasmodium falciparum serine repeat antigen 1 0.0218 0.1761 0.176
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0218 0.1761 0.176
Leishmania major cathepsin L-like protease 0.1181 1 1
Onchocerca volvulus 0.018 0.1438 0.1372
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0394 0.0394
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0409 0.0408
Leishmania major hypothetical protein, conserved 0.0637 0.5344 0.5344
Trypanosoma cruzi major cysteine proteinase, putative 0.0218 0.1761 0.176
Schistosoma mansoni cathepsin B (C01 family) 0.0218 0.1761 0.1761
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0118 0.0909 0.0839
Giardia lamblia DNA damage repair protein 0.0018 0.0048 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.1761 0.176
Brugia malayi Regulator of G protein signaling domain containing protein 0.0057 0.0381 0.038
Echinococcus multilocularis cathepsin L cysteine protease 0.1181 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0608 0.5101 0.5101
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0021 0.0076 0.0076
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0099 0.0098
Brugia malayi Phosphoglycerate kinase 0.0062 0.0424 0.0422
Trichomonas vaginalis chromobox protein, putative 0.0211 0.1703 0.1702
Trichomonas vaginalis CAMK family protein kinase 0.0475 0.3964 0.3963
Trypanosoma brucei unspecified product 0.0039 0.0232 0.0231
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0062 0.0424 0.0422
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0303 0.2491 0.5065
Onchocerca volvulus Cathepsin L homolog 0.1181 1 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0218 0.1761 0.176
Trypanosoma cruzi trypanothione reductase, putative 0.0228 0.1848 0.1847
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Echinococcus multilocularis regulator of G protein signaling 3 0.0057 0.0381 0.038
Onchocerca volvulus 0.1181 1 1
Leishmania major hypothetical protein, conserved 0.0021 0.0076 0.0075
Plasmodium vivax glutathione reductase, putative 0.0228 0.1848 0.1847
Entamoeba histolytica cysteine proteinase, putative 0.1181 1 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0192 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Echinococcus granulosus dna polymerase eta 0.0082 0.0599 0.0597
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0505 0.0505
Leishmania major trypanothione reductase 0.0228 0.1848 0.1847
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0048 0.0046
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0409 0.0698
Mycobacterium ulcerans monoxygenase 0.0021 0.0076 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0099 0.0098
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0094 0.0093
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0777 0.6545 0.6545
Entamoeba histolytica cysteine proteinase 2 0.0608 0.5101 0.5101
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.052 0.4347 0.8958
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0613 0.0612
Echinococcus granulosus peregrin 0.0057 0.0388 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0381 0.038
Toxoplasma gondii cathepsin CPC2 0.0218 0.1761 0.176
Echinococcus multilocularis axis inhibition protein axin 0.0057 0.0381 0.038
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0073 0.0524 0.0706
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0218 0.1761 0.176
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0079 0.0573 0.0571
Giardia lamblia Cathepsin L precursor 0.0218 0.1761 0.2689
Plasmodium falciparum glutathione reductase 0.0079 0.0573 0.0571
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Brugia malayi jmjC domain containing protein 0.0019 0.0055 0.0054
Echinococcus granulosus GPCR family 2 0.0016 0.0029 0.0028
Brugia malayi Cathepsin L-like precursor 0.079 0.666 0.6659
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0409 0.0408
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0523 0.4375 0.4375
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0523 0.4375 0.4375
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0076 0.0075
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0454 0.0452
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0192 0.0191
Brugia malayi Cathepsin L-like precursor 0.1181 1 1
Trypanosoma brucei phosphoglycerate kinase 0.0168 0.1333 0.1331
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Loa Loa (eye worm) thioredoxin reductase 0.0228 0.1848 0.1848
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Trichomonas vaginalis hypothetical protein 0.0035 0.0192 0.0191
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0454 0.0452
Echinococcus granulosus phd:f box containing protein 0.0019 0.0055 0.0054
Giardia lamblia PHD finger protein 15 0.0057 0.0388 0.0591
Echinococcus granulosus regulator of G protein signaling 3 0.0057 0.0381 0.038
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0505 0.0505
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0505 0.0504
Echinococcus granulosus chromatin regulatory protein sir2 0.0777 0.6545 0.6545
Schistosoma mansoni hypothetical protein 0.0035 0.02 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Loa Loa (eye worm) hypothetical protein 0.079 0.666 0.666
Leishmania major hypothetical protein, conserved 0.0021 0.0076 0.0075
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0218 0.1761 0.176
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0021 0.0076 0.0042
Echinococcus multilocularis Chromo domain 0.0035 0.0192 0.0191
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Mycobacterium ulcerans glutaminase 0.0805 0.6789 1
Entamoeba histolytica hypothetical protein 0.0057 0.0381 0.038
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0055 0.0054
Trypanosoma brucei hypothetical protein, conserved 0.0637 0.5344 0.5344
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0424 0.0422
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Giardia lamblia Cathepsin L precursor 0.0218 0.1761 0.2689
Loa Loa (eye worm) hypothetical protein 0.0325 0.2678 0.2678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.1761 0.176
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Onchocerca volvulus 0.0028 0.0139 0.0063
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0228 0.1848 0.3716
Plasmodium vivax unspecified product 0.0608 0.5101 0.5101
Plasmodium falciparum serine repeat antigen 4 0.0218 0.1761 0.176
Trichomonas vaginalis CAMK family protein kinase 0.0475 0.3964 0.3963
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.1761 0.176
Trypanosoma cruzi cysteine peptidase, putative 0.1181 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0904 0.0904
Schistosoma mansoni cathepsin F (C01 family) 0.1181 1 1
Brugia malayi A-kinase anchor protein 10, precursor 0.0057 0.0381 0.038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Loa Loa (eye worm) hypothetical protein 0.0034 0.0183 0.0183
Schistosoma mansoni tyrosinase precursor 0.018 0.1438 0.1438
Brugia malayi cathepsin L precursor 0.0218 0.1761 0.176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Echinococcus multilocularis glutamate synthase 0.0021 0.0076 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0048 0.0046
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0356 0.0354
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0055 0.0055
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0079 0.0573 0.0571
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0057 0.0381 0.0381
Trypanosoma cruzi cysteine proteinase, putative 0.0608 0.5101 0.5101
Onchocerca volvulus 0.0035 0.0192 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.191 0.1909
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0449 0.0449
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0079 0.0573 0.0571
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.1761 0.176
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0218 0.0216
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0058 0.0393 0.0392
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0198 0.0198
Schistosoma mansoni cathepsin S (C01 family) 0.0218 0.1761 0.1761
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0079 0.0573 0.0571
Schistosoma mansoni chromobox protein 0.0035 0.0192 0.0192
Schistosoma mansoni phosphoglycerate kinase 0.0168 0.1333 0.1333
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1181 1 1
Schistosoma mansoni chromatin regulatory protein sir2 0.0198 0.1594 0.1594
Toxoplasma gondii histone deacetylase SIR2-like 0.0198 0.1594 0.1593
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0076 0.0075
Brugia malayi F/Y-rich N-terminus family protein 0.0027 0.0131 0.013
Schistosoma mansoni regulator of G protein signaling 0.0057 0.0381 0.0381
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0218 0.1761 0.176
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0029 0.0028
Echinococcus granulosus glutamate synthase 0.0021 0.0076 0.0075
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0057 0.0384 0.0382
Loa Loa (eye worm) glutaminase 2 0.0805 0.6789 0.6789
Brugia malayi PHD-finger family protein 0.002 0.0071 0.007
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0069 0.0068
Giardia lamblia Encystation-specific protease 0.0218 0.1761 0.2689
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0303 0.2491 0.249
Loa Loa (eye worm) hypothetical protein 0.039 0.3237 0.3237
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0316 0.0316
Brugia malayi hypothetical protein 0.0035 0.02 0.0199
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0608 0.5101 0.5101
Echinococcus granulosus expressed protein 0.1102 0.9329 0.9329
Giardia lamblia Cysteine protease 0.0218 0.1761 0.2689
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0608 0.5101 0.5101
Echinococcus granulosus cathepsin b 0.0218 0.1761 0.176
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0598 0.0597
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0222 0.022
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0218 0.1761 0.176
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0021 0.0076 0.0075
Giardia lamblia Hypothetical protein 0.0218 0.1761 0.2689
Brugia malayi Cathepsin L-like precursor 0.1181 1 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0076 0.0075
Echinococcus multilocularis axis inhibition protein axin 0.0057 0.0381 0.038
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0777 0.6545 0.6545
Mycobacterium ulcerans hypothetical protein 0.0073 0.0524 0.0706
Leishmania major DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Brugia malayi Papain family cysteine protease containing protein 0.1181 1 1
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0777 0.6545 0.6545
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.079 0.666 0.6659
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0303 0.2491 0.249
Plasmodium falciparum serine repeat antigen 9 0.0218 0.1761 0.176
Loa Loa (eye worm) ShTK domain-containing protein 0.018 0.1438 0.1438
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0188 0.1506 0.1504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0608 0.5101 0.5101
Giardia lamblia Cathepsin L-like protease 0.0218 0.1761 0.2689
Loa Loa (eye worm) transcriptional regulator 0.0777 0.6545 0.6545
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0076 0.0075
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0454 0.0452
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0218 0.1761 0.1761
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0055 0.0055
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0218 0.1761 0.1761
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.039 0.3237 0.3236
Echinococcus multilocularis regulator of G protein signaling 0.0057 0.0381 0.038
Giardia lamblia Glutamate synthase 0.0021 0.0076 0.0114
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0029 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0076 0.0075
Brugia malayi cathepsin F-like cysteine proteinase 0.039 0.3237 0.3236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0247 0.0246
Brugia malayi transcriptional regulator, Sir2 family protein 0.0198 0.1594 0.1593
Loa Loa (eye worm) hypothetical protein 0.0218 0.1761 0.1761
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0523 0.4375 0.4375
Brugia malayi TAR-binding protein 0.0065 0.0449 0.0448
Brugia malayi Thioredoxin reductase 0.0228 0.1848 0.1847
Echinococcus multilocularis regulator of G protein signaling 3 0.0057 0.0381 0.038
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0057 0.0056
Plasmodium vivax ferrodoxin reductase, putative 0.0021 0.0076 0.0075
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0454 0.0452
Loa Loa (eye worm) hypothetical protein 0.018 0.1438 0.1438
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0048 0.0046
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0198 0.1594 0.1593
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0218 0.1761 0.176
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0192 0.0191
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0384 0.0384
Echinococcus granulosus axis inhibition protein axin 0.0057 0.0381 0.038
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0777 0.6545 0.6545
Trichomonas vaginalis glutathione reductase, putative 0.0079 0.0573 0.0571
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0218 0.1761 0.1761
Brugia malayi regulator of G-protein signaling egl-10 0.0057 0.0381 0.038
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0076
Leishmania major cathepsin L-like protease 0.1181 1 1
Brugia malayi CHD4 protein 0.0036 0.0206 0.0205
Leishmania major cathepsin L-like protease 0.1181 1 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0168 0.1333 0.2635
Loa Loa (eye worm) ShTK domain-containing protein 0.018 0.1438 0.1438
Mycobacterium leprae Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) 0.0105 0.0793 0.1505
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0021 0.0076 0.0075
Loa Loa (eye worm) tyrosinase 1 0.018 0.1438 0.1438
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0192 0.0191
Echinococcus granulosus dna polymerase kappa 0.0057 0.0384 0.0382
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0388 0.0388
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0199
Brugia malayi ShTK domain containing protein 0.018 0.1438 0.1437
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0598 0.0597
Plasmodium vivax serine-repeat antigen (SERA) 0.0218 0.1761 0.176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0218 0.1761 0.2689
Loa Loa (eye worm) hypothetical protein 0.0057 0.0381 0.0381
Echinococcus multilocularis citrate lyase subunit beta protein 0.0073 0.0524 0.0523
Schistosoma mansoni cpg binding protein 0.003 0.0153 0.0153
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0094 0.0037
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0384 0.0382
Echinococcus granulosus jumonji domain containing protein 0.008 0.058 0.0579
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0388 0.0387
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Echinococcus multilocularis chromobox protein 1 0.0211 0.1703 0.1702
Schistosoma mansoni regulator of G protein signaling 0.0057 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0384 0.0498
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0303 0.2491 0.249
Entamoeba histolytica cysteine protease, putative 0.0218 0.1761 0.176
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0055 0.0054
Echinococcus multilocularis phosphoglycerate kinase 1 0.0168 0.1333 0.1331
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0168 0.1333 0.1331
Leishmania major cathepsin L-like protease 0.1181 1 1
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0168 0.1333 0.1331
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0218 0.1761 0.176
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0073 0.0524 0.0523
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Schistosoma mansoni DNA polymerase eta 0.0082 0.0599 0.0599
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0139 0.0139
Brugia malayi Papain family cysteine protease containing protein 0.0608 0.5101 0.5101
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0192 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0388 0.0387
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0424 0.0422
Entamoeba histolytica cysteine proteinase, putative 0.0608 0.5101 0.5101
Plasmodium vivax phosphoglycerate kinase, putative 0.0168 0.1333 0.1331
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0192 0.0191
Plasmodium falciparum thioredoxin reductase 0.0228 0.1848 0.1847
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0381 0.038
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0168 0.1333 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0608 0.5101 0.5101
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0384 0.0382
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0094 0.0068
Loa Loa (eye worm) PHD-finger family protein 0.0057 0.0388 0.0388
Echinococcus granulosus cathepsin b 0.0218 0.1761 0.176
Brugia malayi Cathepsin L-like precursor 0.079 0.666 0.6659
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0316 0.0315
Echinococcus granulosus thioredoxin glutathione reductase 0.0229 0.1852 0.1851
Mycobacterium ulcerans phosphoglycerate kinase 0.0168 0.1333 0.1906
Plasmodium falciparum serine repeat antigen 8 0.0218 0.1761 0.176
Toxoplasma gondii cathepsin CPL 0.1181 1 1
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0062 0.0424 0.0422
Leishmania major DNA polymerase eta, putative 0.0082 0.0599 0.0597
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0449 0.0449
Plasmodium vivax JmjC domain containing protein 0.0019 0.0055 0.0054
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0409 0.0536
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0218 0.1761 0.176
Brugia malayi Cathepsin L-like precursor 0.1181 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0218 0.1761 0.176
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0381 0.038
Plasmodium falciparum phosphoglycerate kinase 0.0168 0.1333 0.1331
Schistosoma mansoni z-protein (S1r protein) 0.0057 0.0381 0.0381
Schistosoma mansoni glutamate synthase 0.0021 0.0076 0.0076
Loa Loa (eye worm) programmed cell death 8 0.0021 0.0076 0.0076
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0058 0.0394 0.0394
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0079 0.0573 0.0571
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0072 0.0071
Giardia lamblia Hypothetical protein 0.0218 0.1761 0.2689
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0449 0.0449
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0055 0.0054
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0021 0.0076 0.0075
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0062 0.0424 0.0422
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0303 0.2491 0.249
Leishmania major hypothetical protein, conserved 0.0021 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Leishmania major NADH dehydrogenase, putative 0.0021 0.0076 0.0075
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0073 0.0524 0.0523
Schistosoma mansoni glutamate synthase 0.0021 0.0076 0.0076
Leishmania major cathepsin L-like protease 0.1181 1 1
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0055 0.0055
Schistosoma mansoni regulator of G protein signaling 0.0057 0.0381 0.0381
Loa Loa (eye worm) RGS-3 protein 0.0057 0.0381 0.0381
Onchocerca volvulus 0.1181 1 1
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0055 0.0055
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0218 0.1761 0.1761
Brugia malayi regulator of G-protein signaling rgs-7 0.0057 0.0381 0.038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0079 0.0573 0.0779
Giardia lamblia Cysteine protease 0.0218 0.1761 0.2689
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0079 0.0573 0.0571
Plasmodium falciparum glutathione reductase 0.0228 0.1848 0.1847
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0076 0.0075
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0206 0.0206
Schistosoma mansoni cathepsin C 0.0218 0.1761 0.1761
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0909 0.0908
Trypanosoma brucei phosphoglycerate kinase 0.0062 0.0424 0.0422
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0094 0.0142
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0491 0.049
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0094 0.0093
Echinococcus multilocularis cathepsin L 0.0608 0.5101 0.5101
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0218 0.1761 0.176
Giardia lamblia Cathepsin L precursor 0.0218 0.1761 0.2689
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0218 0.1761 0.2689
Plasmodium vivax vivapain-2 0.1181 1 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0384 0.0382
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.1761 0.176
Mycobacterium ulcerans ferredoxin reductase 0.0021 0.0076 0.0042
Echinococcus granulosus regulator of G protein signaling 3 0.0057 0.0381 0.038
Leishmania major phosphoglycerate kinase C, glycosomal 0.0168 0.1333 0.1331
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0057 0.0056
Onchocerca volvulus 0.1181 1 1
Trypanosoma brucei DNA polymerase eta, putative 0.0082 0.0599 0.0597
Schistosoma mansoni chromatin regulatory protein sir2 0.0303 0.2491 0.2491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.1761 0.176
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0247 0.0246
Onchocerca volvulus 0.018 0.1438 0.1372
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0598 0.0598
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.052 0.4347 0.8958
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0777 0.6545 0.6545
Brugia malayi Papain family cysteine protease containing protein 0.0608 0.5101 0.5101
Brugia malayi M-phase phosphoprotein, mpp8 0.0035 0.0192 0.0191
Onchocerca volvulus 0.0218 0.1761 0.1698
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0192 0.0192
Echinococcus granulosus PHD finger protein rhinoceros 0.0057 0.0388 0.0387
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0079 0.0573 0.1042
Brugia malayi Regulator of G protein signaling domain containing protein 0.0057 0.0381 0.038
Brugia malayi RNA binding protein 0.0065 0.0449 0.0448
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.02 0.02
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0199
Loa Loa (eye worm) helicase 0.0035 0.0192 0.0192
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0079 0.0573 0.0779
Loa Loa (eye worm) hypothetical protein 0.0218 0.1761 0.1761
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0183 0.0182
Echinococcus multilocularis peregrin 0.0057 0.0388 0.0387
Schistosoma mansoni axis inhibition protein axin 0.0057 0.0381 0.0381
Leishmania major cathepsin L-like protease 0.1181 1 1
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0192 0.0191
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0048 0.0046
Trypanosoma cruzi polo-like protein kinase, putative 0.0475 0.3964 0.3963
Onchocerca volvulus 0.1181 1 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0021 0.0076 0.0075
Entamoeba histolytica phosphoglycerate kinase, putative 0.0168 0.1333 0.1331
Onchocerca volvulus 0.018 0.1438 0.1372
Giardia lamblia Cathepsin L-like protease 0.0218 0.1761 0.2689
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0079 0.0573 0.0571
Loa Loa (eye worm) hypothetical protein 0.0218 0.1761 0.1761
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0029 0.0028
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0198 0.1594 0.1593
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0192 0.0191
Leishmania major cathepsin L-like protease 0.1181 1 1
Giardia lamblia Cathepsin L precursor 0.0218 0.1761 0.2689
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0218 0.1761 0.176
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Echinococcus granulosus regulator of G protein signaling 7 0.0057 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.079 0.666 0.666
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0388 0.0387
Schistosoma mansoni chromatin regulatory protein sir2 0.0777 0.6545 0.6545
Mycobacterium ulcerans hypothetical protein 0.0021 0.0076 0.0042
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0055 0.0054
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0029 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0598 0.0598
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0206 0.0205
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0076 0.0075
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0004
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0076 0.0042
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Giardia lamblia Cysteine protease 0.0218 0.1761 0.2689
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.1761 0.176
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0057 0.0384 0.0382
Mycobacterium ulcerans Sir2-like regulatory protein 0.0198 0.1594 0.2294
Trypanosoma brucei NADH dehydrogenase 0.0021 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0057 0.0381 0.0381
Schistosoma mansoni tyrosinase precursor 0.018 0.1438 0.1438
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0192
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0076 0.0076
Plasmodium falciparum serine repeat antigen 5 0.0218 0.1761 0.176
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1181 1 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0076 0.0075
Echinococcus multilocularis cathepsin L cysteine protease 0.1181 1 1
Entamoeba histolytica hypothetical protein 0.0035 0.0192 0.0191
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0079 0.0573 0.0571
Brugia malayi CXXC zinc finger family protein 0.0028 0.0139 0.0138
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0449 0.0448
Loa Loa (eye worm) hypothetical protein 0.0218 0.1761 0.1761
Echinococcus multilocularis expressed protein 0.1102 0.9329 0.9329
Loa Loa (eye worm) hypothetical protein 0.0168 0.1333 0.1333
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0232 0.0231
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0021 0.0076 0.0114
Toxoplasma gondii preprocathepsin c precursor, putative 0.0218 0.1761 0.176
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1181 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0055 0.0055
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0079 0.0573 0.0571
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0021 0.0076 0.0042
Loa Loa (eye worm) cathepsin B 0.0218 0.1761 0.1761
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0222 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0247 0.0246
Leishmania major cathepsin L-like protease 0.1181 1 1
Brugia malayi MH2 domain containing protein 0.0118 0.0904 0.0903
Schistosoma mansoni regulator of G protein signaling 0.0057 0.0381 0.0381
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.018 0.1438 0.1437
Echinococcus multilocularis beta adrenergic receptor kinase 0.0058 0.0394 0.0393
Loa Loa (eye worm) PXA domain-containing protein 0.0057 0.0381 0.0381
Leishmania major DNA polymerase kappa, putative 0.0018 0.0048 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0247 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0394 0.0394
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0232 0.0231
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0057 0.0381 0.038
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0192 0.0192
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0058 0.0393 0.0392
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0303 0.2491 0.249
Trypanosoma brucei unspecified product 0.0039 0.0232 0.0231
Brugia malayi Cathepsin L-like precursor 0.1181 1 1
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0168 0.1333 0.1331
Schistosoma mansoni chromobox protein 0.0035 0.0192 0.0192
Loa Loa (eye worm) transcriptional regulator 0.0198 0.1594 0.1594
Plasmodium vivax unspecified product 0.0218 0.1761 0.176
Leishmania major silent information regulator 2, putative 0.0777 0.6545 0.6545
Echinococcus multilocularis regulator of G protein signaling 7 0.0057 0.0381 0.038
Brugia malayi NAD-dependent deacetylase SIRT1 0.0523 0.4375 0.4375
Brugia malayi cathepsin L-like cysteine proteinase 0.0218 0.1761 0.176
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0303 0.2491 0.249
Onchocerca volvulus 0.079 0.666 0.6634
Echinococcus multilocularis PHD finger protein rhinoceros 0.0057 0.0388 0.0387
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0076 0.0075
Trypanosoma cruzi cysteine peptidase, putative 0.039 0.3237 0.3236
Loa Loa (eye worm) glutathione reductase 0.0228 0.1848 0.1848
Trypanosoma brucei trypanothione reductase 0.0228 0.1848 0.1847
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.1761 0.176
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0218 0.1761 0.176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.079 0.666 0.6659
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0454 0.0452
Mycobacterium ulcerans hypothetical protein 0.0073 0.0524 0.0706
Trichomonas vaginalis CAMK family protein kinase 0.0475 0.3964 0.3963
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0076 0.0075
Brugia malayi glutathione reductase 0.0228 0.1848 0.1847
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0192 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.3964 0.3964
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0076 0.0075
Trypanosoma cruzi cruzipain precursor, putative 0.1181 1 1
Schistosoma mansoni hypothetical protein 0.0035 0.0192 0.0192
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.1181 1 1
Onchocerca volvulus 0.1181 1 1
Entamoeba histolytica hypothetical protein 0.0218 0.1761 0.176
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0021 0.0076 0.0075
Echinococcus granulosus cathepsin L 0.0608 0.5101 0.5101
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Plasmodium vivax vivapain-1 0.0608 0.5101 0.5101
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0192 0.0191
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0198 0.1594 0.1593
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Schistosoma mansoni hypothetical protein 0.0019 0.0057 0.0057
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0076 0.0075
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0192 0.0191
Entamoeba histolytica serine/threonine protein kinase, putative 0.0475 0.3964 0.3963
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0076 0.0075
Schistosoma mansoni chromobox protein 0.0211 0.1703 0.1703
Onchocerca volvulus Cathepsin F homolog 0.1181 1 1
Brugia malayi jmjC domain containing protein 0.0188 0.1506 0.1504
Chlamydia trachomatis phosphoglycerate kinase 0.0168 0.1333 1
Loa Loa (eye worm) glutaminase 0.0805 0.6789 0.6789
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1181 1 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0094 0.0142
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0048 0.0046
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0005 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0094 0.0093
Plasmodium vivax hypothetical protein, conserved 0.002 0.0072 0.0071
Onchocerca volvulus 0.1181 1 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.052 0.4347 0.8958
Brugia malayi glutaminase DH11.1 0.0805 0.6789 0.6788
Brugia malayi chromobox protein homolog 3 0.0118 0.0909 0.0908
Toxoplasma gondii cathepsin B 0.0218 0.1761 0.176
Loa Loa (eye worm) hypothetical protein 0.0093 0.069 0.069
Trypanosoma cruzi cruzipain precursor, putative 0.039 0.3237 0.3236
Echinococcus granulosus chromobox protein 1 0.0211 0.1703 0.1702
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0057 0.0381 0.038
Leishmania major sir2-family protein-like protein 0.0198 0.1594 0.1593
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0021 0.0076 0.0075
Schistosoma mansoni hypothetical protein 0.0057 0.0388 0.0388
Schistosoma mansoni glutaminase 0.0805 0.6789 0.6789
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0117 0.0117
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0218 0.1761 0.176
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0198 0.1594 0.1593
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0012 0.0001 0.0001
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0192 0.0191
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0777 0.6545 0.6545
Loa Loa (eye worm) RNA binding protein 0.0065 0.0449 0.0449
Echinococcus multilocularis cathepsin b 0.0218 0.1761 0.176
Plasmodium vivax thioredoxin reductase, putative 0.0228 0.1848 0.1847
Giardia lamblia DINP protein human, muc B family 0.0057 0.0384 0.0584
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0127 0.0986 0.0917
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0454 0.0452
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0192 0.0191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0409 0.0408
Echinococcus granulosus cathepsin L cysteine proteinase 0.1181 1 1
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0048 0.0046
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0218 0.1761 0.176
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0079 0.0573 0.0573
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.1761 0.176
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.0475 0.3964 0.3963
Giardia lamblia Cysteine protease 0.0218 0.1761 0.2689
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1
Plasmodium falciparum phd finger protein, putative 0.0057 0.0388 0.0387
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0073 0.0524 0.0523
Schistosoma mansoni regulator of G protein signaling 0.0057 0.0381 0.0381
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Trypanosoma brucei cysteine peptidase C (CPC) 0.0218 0.1761 0.176
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0454 0.0454
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0055 0.0054
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0608 0.5101 0.5101
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0079 0.0573 0.0571
Trichomonas vaginalis CAMK family protein kinase 0.0475 0.3964 0.3963
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0021 0.0076 0.0075
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0057 0.0388 0.0388
Onchocerca volvulus 0.0035 0.0198 0.0122
Trypanosoma cruzi cysteine peptidase, putative 0.1181 1 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.052 0.4347 0.8958
Giardia lamblia Sirtuin type 2 0.0198 0.1594 0.2434
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0218 0.1761 0.2689
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0079 0.0573 0.0571
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0199
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0206 0.0206
Echinococcus granulosus chromobox protein 2 0.0035 0.0192 0.0191
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0218 0.1761 0.2689
Loa Loa (eye worm) hypothetical protein 0.0019 0.0055 0.0055
Plasmodium falciparum serine repeat antigen 7 0.0218 0.1761 0.176
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0057 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.039 0.3237 0.3237
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0232 0.0231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0247 0.0246
Loa Loa (eye worm) hypothetical protein 0.039 0.3237 0.3237
Echinococcus granulosus tar DNA binding protein 0.0065 0.0449 0.0448
Trichomonas vaginalis chromobox protein, putative 0.0211 0.1703 0.1702
Schistosoma mansoni cpg binding protein 0.003 0.0153 0.0153
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0303 0.2491 0.249
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0192 0.0191
Brugia malayi cathepsin Z-like cysteine proteinase 0.0218 0.1761 0.176
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0058 0.0394 0.0394
Schistosoma mansoni microtubule-associated protein tau 0.068 0.5719 0.5719
Loa Loa (eye worm) transcriptional regulator 0.0198 0.1594 0.1594
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0055 0.0055
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0021 0.0076 0.0075
Brugia malayi jmjC domain containing protein 0.0019 0.0055 0.0054
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0192 0.0191
Brugia malayi jmjC domain containing protein 0.0071 0.0505 0.0504
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0219 0.0218
Mycobacterium ulcerans dehydrogenase 0.0021 0.0076 0.0042
Echinococcus granulosus cathepsin L 0.0218 0.1761 0.176
Brugia malayi hypothetical protein 0.0035 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0192
Entamoeba histolytica cysteine protease, putative 0.0218 0.1761 0.176
Loa Loa (eye worm) papain family cysteine protease containing protein 0.039 0.3237 0.3237
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0384 0.0384
Trypanosoma brucei phosphoglycerate kinase 0.0168 0.1333 0.1331
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0454 0.0452
Echinococcus multilocularis Regulator of G protein signaling 20 0.0057 0.0381 0.038
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0218 0.1761 0.176
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0029
Treponema pallidum phosphoglycerate kinase 0.0168 0.1333 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0449 0.0449
Mycobacterium tuberculosis Conserved protein 0.0073 0.0524 0.0939
Schistosoma mansoni cathepsin F (C01 family) 0.079 0.666 0.666
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0055 0.0054
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0048 0.0046
Echinococcus multilocularis microtubule associated protein 2 0.068 0.5719 0.5719
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0198 0.1594 0.1593
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0076 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0475 0.3964 0.3918
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0094 0.0142
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0073 0.0524 0.0706
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.02 0.0199
Leishmania major phosphoglycerate kinase B, cytosolic 0.0168 0.1333 0.1331
Giardia lamblia Cathepsin L precursor 0.0218 0.1761 0.2689
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0021 0.0076 0.0075
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0303 0.2491 0.249
Echinococcus multilocularis chromobox protein 2 0.0035 0.0192 0.0191
Onchocerca volvulus Alhambra homolog 0.0057 0.0388 0.0314
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0218 0.1761 0.176
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0076 0.0075
Onchocerca volvulus Cathepsin L homolog 0.0218 0.1761 0.1698
Schistosoma mansoni chromatin regulatory protein sir2 0.0523 0.4375 0.4375
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0475 0.3964 0.3963
Trichomonas vaginalis chromobox protein, putative 0.0127 0.0986 0.0985
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0021 0.0076 0.0075
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0021 0.0076 0.0075
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0192 0.0191
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0076 0.0075
Schistosoma mansoni chromatin regulatory protein sir2 0.0198 0.1594 0.1594
Brugia malayi jmjC domain containing protein 0.0019 0.0055 0.0054
Schistosoma mansoni cpg binding protein 0.0028 0.0139 0.0139
Echinococcus granulosus bloom syndrome protein 0.0024 0.0099 0.0098
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0055 0.0055
Schistosoma mansoni glutamate synthase 0.0021 0.0076 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0637 0.5344 0.5344
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.079 0.666 0.6659
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0032 0.0031
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0029
Brugia malayi ImpB/MucB/SamB family protein 0.0082 0.0599 0.0597
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0076 0.0075
Brugia malayi glutamate synthase 0.0021 0.0076 0.0075
Leishmania major hypothetical protein, conserved 0.0019 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Plasmodium falciparum serine repeat antigen 2 0.0218 0.1761 0.176
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0192
Entamoeba histolytica cysteine proteinase, putative 0.1181 1 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0055 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Loa Loa (eye worm) ctsf protein 0.1181 1 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0192 0.0191
Brugia malayi Cathepsin L-like precursor 0.039 0.3237 0.3236
Entamoeba histolytica cysteine protease, putative 0.1181 1 1
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0076 0.0075
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0099 0.0098
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0578 0.4844 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0029 0.0028
Plasmodium vivax serine-repeat antigen (SERA) 0.0218 0.1761 0.176
Trypanosoma brucei SIR2-like protein 4, putative 0.0198 0.1594 0.1593
Entamoeba histolytica thioredoxin reductase, putative 0.0021 0.0076 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0384 0.0382
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Echinococcus granulosus cysteine protease 0.0608 0.5101 0.5101
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.1761 0.1761
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0168 0.1333 0.1331
Leishmania major DNA damage repair protein, putative 0.0018 0.0048 0.0046
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0218 0.1761 0.176
Schistosoma mansoni chromatin regulatory protein sir2 0.0777 0.6545 0.6545
Plasmodium vivax vivapain-2 0.1181 1 1
Echinococcus multilocularis cysteine protease 0.1181 1 1
Entamoeba histolytica cysteine protease, putative 0.0218 0.1761 0.176
Giardia lamblia Cathepsin B precursor 0.0218 0.1761 0.2689
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0076 0.0075
Echinococcus granulosus axis inhibition protein axin 0.0057 0.0381 0.038
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0076 0.0075
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0057 0.0381 0.038
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0029
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0523 0.4375 0.4375
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0608 0.5101 0.5101
Echinococcus multilocularis cpg binding protein 0.003 0.0153 0.0151
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0218 0.1761 0.1761
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0192 0.0191
Plasmodium falciparum cysteine proteinase falcipain 1 0.0608 0.5101 0.5101
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.052 0.4347 0.8958
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0076 0.0075
Trypanosoma cruzi cysteine peptidase, putative 0.1181 1 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0424 0.0422
Plasmodium vivax vivapain-3 0.0608 0.5101 0.5101
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0048 0.0046
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0206 0.0205
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0021 0.0076 0.0075
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0075 0.0073
Onchocerca volvulus 0.1181 1 1
Loa Loa (eye worm) hypothetical protein 0.079 0.666 0.666
Leishmania major DNA polymerase eta, putative 0.0043 0.0263 0.0261
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0218 0.1761 0.1761
Echinococcus multilocularis GPCR, family 2 0.0016 0.0029 0.0028
Brugia malayi fibroinase precursor 0.0218 0.1761 0.176
Loa Loa (eye worm) RecQ helicase 0.0024 0.0099 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.0475 0.3964 0.3963
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0057 0.0381 0.0381
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0048 0.0046
Trypanosoma cruzi trypanothione reductase, putative 0.0079 0.0573 0.0571
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0057 0.0057
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.0911 0.0911
Schistosoma mansoni chromobox protein 0.0211 0.1703 0.1703
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.018 0.1438 0.1437
Brugia malayi Phosphoglycerate kinase 0.0168 0.1333 0.1331
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0454 0.0452
Loa Loa (eye worm) hypothetical protein 0.0523 0.4375 0.4375
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.191 0.1909
Trichomonas vaginalis mercuric reductase, putative 0.0079 0.0573 0.0571
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0247 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.1761 0.176
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0057 0.0381 0.0381
Mycobacterium ulcerans NADH dehydrogenase 0.0021 0.0076 0.0042
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0409 0.0409
Echinococcus granulosus cathepsin l1 0.079 0.666 0.6659
Echinococcus multilocularis chromatin regulatory protein sir2 0.0777 0.6545 0.6545
Onchocerca volvulus 0.018 0.1438 0.1372
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0192 0.0191
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0263 0.0261
Brugia malayi jmjC domain containing protein 0.0019 0.0055 0.0054
Brugia malayi AF-10 protein 0.0019 0.0057 0.0056
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0578 0.4844 1
Onchocerca volvulus 0.0093 0.069 0.0619
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0079 0.0573 0.0571
Brugia malayi cathepsin Z-like cysteine proteinase 0.0218 0.1761 0.176
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0076 0.0075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0384 0.0645
Brugia malayi PHD-finger family protein 0.0057 0.0388 0.0387
Echinococcus multilocularis thioredoxin glutathione reductase 0.0229 0.1852 0.1851
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0076 0.0075
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.018 0.1438 0.1437
Brugia malayi SET domain containing protein 0.0035 0.0198 0.0196
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0449 0.0448
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0057 0.0056
Giardia lamblia Cathepsin L precursor 0.0218 0.1761 0.2689
Echinococcus multilocularis dna polymerase eta 0.0082 0.0599 0.0597
Entamoeba histolytica cysteine protease, putative 0.0608 0.5101 0.5101
Plasmodium falciparum serine repeat antigen 3 0.0218 0.1761 0.176
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0021 0.0076 0.0075
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0094 0.0093
Echinococcus granulosus regulator of G protein signaling 7 0.0057 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.0218 0.1761 0.1761
Loa Loa (eye worm) hypothetical protein 0.0119 0.0916 0.0916
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0021 0.0076 0.0075
Plasmodium falciparum thioredoxin reductase 0.0079 0.0573 0.0571
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1181 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0613 0.0612
Schistosoma mansoni hypothetical protein 0.0034 0.0183 0.0183
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0076 0.0075
Schistosoma mansoni hypothetical protein 0.0021 0.0076 0.0076
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0021 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0218 0.1761 0.1761
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0079 0.0573 0.0571
Entamoeba histolytica hypothetical protein 0.0023 0.0094 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.1761 0.176
Toxoplasma gondii histone deacetylase SIR2 0.0303 0.2491 0.249
Echinococcus granulosus Chromobox protein 3 0.0035 0.0192 0.0191
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0449 0.0449
Echinococcus multilocularis regulator of G protein signaling 7 0.0057 0.0381 0.038
Mycobacterium tuberculosis Probable oxidoreductase 0.0578 0.4844 1
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0055 0.0054
Brugia malayi hypothetical protein 0.0057 0.0381 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.1761 0.176
Brugia malayi PXA domain containing protein 0.0057 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.018 0.1438 0.1438
Entamoeba histolytica cysteine proteinase, putative 0.0608 0.5101 0.5101
Trypanosoma cruzi cysteine peptidase, putative 0.0608 0.5101 0.5101
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0904 0.0904
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0076 0.0075
Echinococcus multilocularis chromobox protein 1 0.0211 0.1703 0.1702
Brugia malayi Bromodomain containing protein 0.0057 0.0388 0.0387
Loa Loa (eye worm) hypothetical protein 0.0118 0.0909 0.0909
Entamoeba histolytica hypothetical protein, conserved 0.0198 0.1594 0.1593
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0192 0.0191
Mycobacterium ulcerans NAD-dependent deacetylase 0.0303 0.2491 0.3625
Trypanosoma cruzi cysteine proteinase, putative 0.0608 0.5101 0.5101
Echinococcus granulosus cathepsin l1 0.1181 1 1
Entamoeba histolytica hypothetical protein 0.0057 0.0381 0.038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1181 1 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0079 0.0573 0.0571
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.1761 0.176
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0055 0.0055
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0076 0.0042
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0021 0.0076 0.0042
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0384 0.0382
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0055 0.0054
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0094 0.0037
Onchocerca volvulus 0.0082 0.0598 0.0526
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0384 0.0382
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1181 1 1

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 6 % Displacement of [3H]N6-[(R)-1-methyl-2-phenylethyl]adenosine from human recombinant A1AR expressed in CHO cells at 10 uM ChEMBL. 24931275
Inhibition (binding) = 19 % Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-50-N-ethylcarboxamidoadenosine from human recombinant A2AR expressed in HEK293 cells at 10 uM ChEMBL. 24931275
Inhibition (binding) = 32 % Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-50-N-methyluronamide from human recombinant A3AR expressed in CHO cells at 10 uM ChEMBL. 24931275

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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