Detailed information for compound 916966

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 252.29 | Formula: C11H12N2O3S
  • H donors: 1 H acceptors: 4 LogP: 0.98 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(c2c1nccc2)S(=O)(=O)N(C)C
  • InChi: 1S/C11H12N2O3S/c1-13(2)17(15,16)10-6-5-9(14)11-8(10)4-3-7-12-11/h3-7,14H,1-2H3
  • InChiKey: HBPLBDZSCQMJEA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0214 0.6215 0.8647
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0099 0.2491 0.3163
Giardia lamblia Kinase, CMGC GSK 0.0099 0.2491 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0561 0.066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0867 0.1092
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.5062 0.6555
Echinococcus granulosus geminin 0.0174 0.4926 0.6375
Loa Loa (eye worm) hypothetical protein 0.004 0.058 0.0414
Giardia lamblia Kinase, PLK 0.0098 0.2457 0.9846
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0273 0.0015
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0214 0.6215 0.8647
Onchocerca volvulus 0.0243 0.7173 1
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0214 0.6215 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0261 0.0205
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0477 0.0505
Loa Loa (eye worm) hypothetical protein 0.0085 0.2049 0.24
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0477 0.0505
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0094 0.006
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0261 0.0205
Echinococcus multilocularis survival motor neuron protein 1 0.0259 0.7673 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0199 0.5749 0.8874
Schistosoma mansoni kinase 0.005 0.0909 0.0802
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0273 0.0235
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.4352 0.432
Echinococcus granulosus fatty acid amide hydrolase 1 0.0109 0.2809 0.3581
Entamoeba histolytica hypothetical protein 0.0037 0.0477 0.0682
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.5062 0.6555
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2457 0.3338
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.2457 0.3202
Leishmania major monoglyceride lipase, putative 0.0214 0.6215 0.6193
Mycobacterium tuberculosis Conserved protein 0.0025 0.0094 0.0058
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0261 0.022
Trypanosoma brucei protein kinase, putative 0.0099 0.2491 0.2448
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0477 0.0267
Mycobacterium tuberculosis Probable reductase 0.0199 0.5749 0.8874
Plasmodium falciparum lysophospholipase, putative 0.0214 0.6215 1
Brugia malayi chromobox protein homolog 3 0.004 0.058 0.0755
Trichomonas vaginalis chromobox protein, putative 0.0072 0.16 0.2127
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.2457 0.2385
Schistosoma mansoni fatty-acid amide hydrolase 0.0109 0.2809 0.3153
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0109 0.2809 0.3581
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0099 0.2491 0.276
Plasmodium vivax glycogen synthase kinase 3, putative 0.0099 0.2491 0.3953
Trypanosoma brucei mitochondrial DNA polymerase beta 0.033 1 1
Trichomonas vaginalis chromobox protein, putative 0.0072 0.16 0.2127
Schistosoma mansoni alpha-glucosidase 0.0153 0.4257 0.4945
Trichomonas vaginalis set domain proteins, putative 0.0243 0.7173 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.02 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.02 0.0148
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0678 0.0553
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.2457 0.2951
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0561 0.066
Toxoplasma gondii thioredoxin reductase 0.0087 0.2115 0.8453
Trypanosoma brucei hypothetical protein, conserved 0.0218 0.6368 0.6347
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2457 0.3338
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0099 0.2491 0.2448
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0214 0.6215 0.9601
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0261 0.0235
Brugia malayi Pre-SET motif family protein 0.0214 0.6215 0.8099
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0261 0.0205
Echinococcus multilocularis geminin 0.0174 0.4926 0.6375
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0099 0.2491 0.3163
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0222 0.6471 1
Plasmodium falciparum lysophospholipase, putative 0.0214 0.6215 1
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0099 0.2491 0.242
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0786 0.0698
Loa Loa (eye worm) hypothetical protein 0.0031 0.0298 0.0034
Echinococcus multilocularis chromobox protein 1 0.0072 0.16 0.1987
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.6215 0.8029
Loa Loa (eye worm) hypothetical protein 0.0259 0.7673 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0261 0.0331
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0261 0.0205
Echinococcus granulosus thioredoxin glutathione reductase 0.0088 0.2132 0.2688
Echinococcus granulosus protein kinase shaggy 0.0099 0.2491 0.3163
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.2457 0.3117
Schistosoma mansoni chromobox protein 0.0072 0.16 0.1657
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2457 0.3338
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0273 0.0235
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.058 0.0409
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0561 0.0819
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0222 0.6471 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.2457 0.2385
Brugia malayi hypothetical protein 0.0037 0.0477 0.0622
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0099 0.2491 0.2998
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0561 0.0819
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0273 0.0886
Trypanosoma brucei polo-like protein kinase 0.0098 0.2457 0.2413
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0168
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0156 0.4352 0.432
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0273 0.0015
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.2049 0.2579
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0094 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0214 0.6215 0.8647
Plasmodium vivax SET domain protein, putative 0.0031 0.0273 0.035
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0261 0.034
Schistosoma mansoni chromobox protein 0.0072 0.16 0.1657
Loa Loa (eye worm) hypothetical protein 0.0109 0.2809 0.3427
Entamoeba histolytica protein kinase domain containing protein 0.0099 0.2491 0.3953
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0214 0.6215 0.8647
Plasmodium falciparum lysophospholipase, putative 0.0214 0.6215 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0273 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.6368 0.6334
Brugia malayi Pre-SET motif family protein 0.0031 0.0273 0.0356
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2457 0.3338
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0261 0.0331
Mycobacterium ulcerans lysophospholipase 0.0214 0.6215 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0561 0.066
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0561 0.0471
Schistosoma mansoni hypothetical protein 0.0174 0.4926 0.5773
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0786 0.0698
Onchocerca volvulus 0.0042 0.0653 0.0516
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0561 0.0507
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0168
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0205
Brugia malayi MH2 domain containing protein 0.0123 0.3257 0.4245
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0099 0.2491 1
Trypanosoma cruzi monoglyceride lipase, putative 0.0214 0.6215 0.6179
Schistosoma mansoni hypothetical protein 0.0037 0.0477 0.0267
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0205
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0168
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0261 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2457 0.3338
Loa Loa (eye worm) glutathione reductase 0.0087 0.2115 0.2489
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.3257 0.4033
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0214 0.6215 0.8647
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0214 0.6215 0.8647
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0561 0.039
Trypanosoma cruzi trypanothione reductase, putative 0.0087 0.2115 0.2039
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0261 1
Onchocerca volvulus 0.0085 0.2049 0.2547
Echinococcus multilocularis protein kinase shaggy 0.0099 0.2491 0.3163
Brugia malayi amidase 0.0109 0.2809 0.366
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0222 0.6471 1
Mycobacterium ulcerans hypothetical protein 0.0174 0.4926 0.7906
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.6368 0.6334
Echinococcus granulosus survival motor neuron protein 1 0.0259 0.7673 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0261 0.0331
Onchocerca volvulus 0.0053 0.099 0.1006
Leishmania major trypanothione reductase 0.0087 0.2115 0.2069
Brugia malayi glutathione reductase 0.0087 0.2115 0.2756
Echinococcus multilocularis thioredoxin glutathione reductase 0.0088 0.2132 0.2688
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0867 0.1092
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.2457 0.314
Mycobacterium tuberculosis Probable oxidoreductase 0.0222 0.6471 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0561 0.2071
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0261 0.0235
Treponema pallidum NADH oxidase 0.003 0.0261 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0786 0.0732
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0168
Entamoeba histolytica protein kinase domain containing protein 0.0099 0.2491 0.3953
Schistosoma mansoni hypothetical protein 0.0053 0.099 0.0903
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0261 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0261 0.022
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0199 0.5749 0.8874
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0561 0.0732
Mycobacterium tuberculosis Possible lysophospholipase 0.0214 0.6215 0.9601
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0236 0.0187
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0109 0.2809 0.3581
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.033 1 1
Giardia lamblia Kinase, CMGC GSK 0.0099 0.2491 1
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.2491 0.3386
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.2457 0.2718
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0561 0.0471
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0561 0.0616
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0653 0.0485
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.1115 0.1031
Plasmodium vivax PST-A protein 0.0214 0.6215 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0199 0.5749 0.8874
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.2049 0.2579
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0561 0.066
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0261 0.0168
Schistosoma mansoni amidase 0.0109 0.2809 0.3153
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.2457 0.2413
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0261 0.0168
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.5062 0.6555
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0678 0.0825
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.033 1 1
Brugia malayi hypothetical protein 0.0259 0.7673 1
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0094 0.006
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0261 0.0168
Echinococcus granulosus chromobox protein 1 0.0072 0.16 0.1987
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.3257 0.4033
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0094 0.0037
Trypanosoma brucei monoglyceride lipase, putative 0.0214 0.6215 0.6193
Mycobacterium ulcerans hypothetical protein 0.0025 0.0094 0.006
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.2457 0.3897
Mycobacterium ulcerans hypothetical protein 0.0025 0.0094 0.006
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0199 0.5749 0.8874
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0678 0.0825
Entamoeba histolytica hypothetical protein 0.0037 0.0477 0.0682
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0261 0.0331
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0561 0.066
Trypanosoma brucei glucosidase, putative 0.004 0.0561 0.0507
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.16 0.1793
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0261 0.0837
Brugia malayi Heterochromatin protein 1 0.0072 0.16 0.2085
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.2049 0.267
Plasmodium falciparum glycogen synthase kinase 3 0.0099 0.2491 0.3953
Plasmodium falciparum thioredoxin reductase 0.003 0.0261 0.0331
Plasmodium falciparum glutathione reductase 0.003 0.0261 0.0331
Schistosoma mansoni hypothetical protein 0.0174 0.4926 0.5773
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0261 0.0205
Onchocerca volvulus 0.0099 0.2491 0.319
Toxoplasma gondii hypothetical protein 0.0053 0.1007 0.3903
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0214 0.6215 1
Loa Loa (eye worm) thioredoxin reductase 0.0087 0.2115 0.2489
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.5062 0.6597
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0561 0.066
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.2049 0.2213
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.2457 0.3117
Entamoeba histolytica hypothetical protein 0.0037 0.0477 0.0682
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0261 0.0331
Plasmodium falciparum esterase, putative 0.0214 0.6215 1
Leishmania major hypothetical protein, conserved 0.0218 0.6368 0.6347
Onchocerca volvulus 0.0103 0.2623 0.3382
Mycobacterium ulcerans hypothetical protein 0.0214 0.6215 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0261 0.0205
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0261 0.0168
Mycobacterium tuberculosis Probable dehydrogenase 0.0199 0.5749 0.8874
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.5062 0.6472
Plasmodium vivax glutathione reductase, putative 0.0087 0.2115 0.3341
Entamoeba histolytica protein kinase, putative 0.0099 0.2491 0.3953
Plasmodium falciparum thioredoxin reductase 0.0087 0.2115 0.3341
Brugia malayi intracellular kinase 0.0099 0.2491 0.3247
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0099 0.2491 0.2998
Echinococcus multilocularis chromobox protein 1 0.0072 0.16 0.1987
Entamoeba histolytica hypothetical protein 0.0037 0.0477 0.0682
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0561 0.066
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.2491 0.3386
Trypanosoma brucei monoglyceride lipase, putative 0.0214 0.6215 0.6193
Schistosoma mansoni alpha-glucosidase 0.0153 0.4257 0.4945
Trypanosoma brucei trypanothione reductase 0.0087 0.2115 0.2069
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0087 0.2115 0.3208
Schistosoma mansoni alpha glucosidase 0.004 0.0561 0.0372
Trichomonas vaginalis conserved hypothetical protein 0.0214 0.6215 0.8647
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0261 0.0331
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.4352 0.4298
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.099 0.1291
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0261 0.0837
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.4926 0.7591
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2457 0.3338
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0273 0.0235
Plasmodium vivax thioredoxin reductase, putative 0.0087 0.2115 0.3341
Trichomonas vaginalis conserved hypothetical protein 0.004 0.058 0.0685
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0199 0.5749 0.8874
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0786 0.0698
Brugia malayi Thioredoxin reductase 0.0087 0.2115 0.2756
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0561 0.066
Schistosoma mansoni survival motor neuron protein 0.0053 0.099 0.0903
Echinococcus granulosus fatty acid amide hydrolase 1 0.0109 0.2809 0.3581
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0561 0.0616
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0261 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0214 0.6215 0.8647
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0561 0.066
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2457 0.3338
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0261 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.004 0.058 0.0685
Echinococcus granulosus chromobox protein 1 0.0072 0.16 0.1987
Plasmodium falciparum glutathione reductase 0.0087 0.2115 0.3341
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0094 0.0058

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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