Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0886 | 0.1404 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0037 | 0.6311 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0.2569 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0886 | 0.1404 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.0011 | 0 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.2569 | 0.4071 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0886 | 0.1404 |
Echinococcus granulosus | expressed protein | 0.0037 | 0.6532 | 0.5333 |
Schistosoma mansoni | rotamase | 0.0037 | 0.6532 | 0.5333 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.2569 | 0.5 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0037 | 0.6311 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0037 | 0.6532 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Leishmania major | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0037 | 0.6311 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0886 | 0.1404 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0037 | 0.6311 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.2569 | 0.4071 |
Trichomonas vaginalis | rotamase, putative | 0.0037 | 0.6311 | 0.9442 |
Giardia lamblia | DINP protein human, muc B family | 0.0022 | 0.2569 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.6532 | 1 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0886 | 0.1404 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0037 | 0.6311 | 1 |
Echinococcus multilocularis | expressed protein | 0.0037 | 0.6532 | 0.5333 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0037 | 0.6532 | 0.5333 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.2569 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0037 | 0.6311 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.2569 | 0.5 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0037 | 0.6532 | 0.5333 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.2569 | 0.4071 |
Leishmania major | DNA polymerase eta, putative | 0.0022 | 0.2569 | 0.4071 |
Trypanosoma brucei | unspecified product | 0.0022 | 0.2569 | 0.4071 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.