Detailed information for compound 919733

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 453.769 | Formula: C17H14ClF6N5O
  • H donors: 1 H acceptors: 3 LogP: 5.42 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: FCCCOc1cc(F)c(c(c1)F)c1c(Cl)nc2n(c1N[C@H](C(F)(F)F)C)ncn2
  • InChi: 1S/C17H14ClF6N5O/c1-8(17(22,23)24)27-15-13(14(18)28-16-25-7-26-29(15)16)12-10(20)5-9(6-11(12)21)30-4-2-3-19/h5-8,27H,2-4H2,1H3/t8-/m0/s1
  • InChiKey: JXMIMJPTFCQEBD-QMMMGPOBSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine proteinase 1, putative 0.0094 0.05 0.3022
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0081 0.048
Trypanosoma cruzi cruzipain precursor, putative 0.0049 0.0233 0.0636
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0331 0.0905
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0161 0.0156
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0151 0.0146
Schistosoma mansoni tar DNA-binding protein 0.0133 0.073 0.2007
Loa Loa (eye worm) TAR-binding protein 0.0133 0.073 0.2007
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0082 0.0429 0.0425
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.006 0.0151
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0009 0.0004
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0214 0.1208 1
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0419
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0045 0.0212 0.1231
Brugia malayi PHD-finger family protein 0.0029 0.0115 0.0316
Brugia malayi fibroinase precursor 0.0045 0.0212 0.0581
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0225 0.1271 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0151 0.0415
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0245 0.1923
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0138 0.1106
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0303 0.2477
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0245 0.1431
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0013 0.0021 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0045 0.0212 0.1231
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0058 0.0145
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0117 0.0317
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0245 0.0667
Plasmodium falciparum serine repeat antigen 5 0.0045 0.0212 0.4226
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.006 0.0055
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.01 0.0747
Schistosoma mansoni hypothetical protein 0.0036 0.0155 0.0426
Plasmodium falciparum serine repeat antigen 9 0.0045 0.0212 0.4226
Plasmodium vivax replication factor C subunit 1, putative 0.0011 0.0009 0.018
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0771 0.0767
Schistosoma mansoni cathepsin s 0.0049 0.0233 0.0641
Echinococcus multilocularis nibrin 0.0011 0.0009 0.0004
Brugia malayi cathepsin Z-like cysteine proteinase 0.0045 0.0212 0.0581
Brugia malayi MAP kinase sur-1 0.0051 0.0245 0.0672
Brugia malayi Cytochrome P450 family protein 0.001 0.0005 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.01 0.122
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0013 0.0021 0.0073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0113 0.0297
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0161 0.0922
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.006 0.0055
Echinococcus multilocularis peregrin 0.0032 0.0136 0.013
Onchocerca volvulus Alhambra homolog 0.0029 0.0115 0.0804
Onchocerca volvulus 0.0235 0.1332 1
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0021 0.0125
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.05 0.2983
Entamoeba histolytica hypothetical protein 0.0036 0.0155 0.0937
Loa Loa (eye worm) hypothetical protein 0.0029 0.0115 0.0316
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Entamoeba histolytica cysteine protease, putative 0.0045 0.0212 0.1278
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0013 0.0021 0.0412
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0045 0.0212 0.423
Echinococcus multilocularis protein dispatched 1 0.0054 0.026 0.0255
Brugia malayi hypothetical protein 0.0011 0.0009 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0094 0.05 0.3022
Loa Loa (eye worm) hypothetical protein 0.0047 0.0221 0.0607
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0009 0.0071
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0045 0.0212 0.0581
Loa Loa (eye worm) inositol-1 0.0037 0.0161 0.0441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Plasmodium falciparum serine repeat antigen 1 0.0045 0.0212 0.4226
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0005 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0119 0.0327
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0009 0.0024
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0133 0.073 0.2007
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0117 0.092
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0652 0.8345
Echinococcus granulosus cathepsin b 0.0627 0.3637 1
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0021 0.0419
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.006 0.1199
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0886
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0058 0.0288 0.0786
Mycobacterium ulcerans hypothetical protein 0.0024 0.0088 0.1069
Giardia lamblia Cysteine protease 0.0045 0.0212 0.1231
Plasmodium vivax glutathione reductase, putative 0.0085 0.0443 0.885
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0061 0.1209
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0161 0.0922
Leishmania major hypothetical protein, conserved 0.0211 0.119 0.9361
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0627 0.3637 1
Loa Loa (eye worm) hypothetical protein 0.0109 0.0589 0.1619
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0058 0.0152
Giardia lamblia Cathepsin L precursor 0.0045 0.0212 0.1231
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0273
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0045 0.0212 0.1278
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0317
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.001 0.0005 0.0008
Brugia malayi Cathepsin L-like precursor 0.0094 0.05 0.1375
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.01 0.122
Trypanosoma cruzi cysteine peptidase, putative 0.0094 0.05 0.1371
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0013 0.0021 0.0044
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0045 0.0212 0.4226
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0117 0.0317
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0058 0.0415
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.001 0.0005 0.0008
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0081 0.0638
Trypanosoma cruzi major cysteine proteinase, putative 0.0045 0.0212 0.0576
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.006 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0205 0.0564
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0045 0.0212 0.1231
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.058
Loa Loa (eye worm) RecQ helicase 0.0019 0.0058 0.0157
Trypanosoma brucei trypanothione reductase 0.0085 0.0443 0.3483
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0058 0.0157
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0115 0.0316
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0165
Mycobacterium tuberculosis Probable dehydrogenase 0.0193 0.1081 0.8946
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0317
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0024
Giardia lamblia Cysteine protease 0.0045 0.0212 0.1231
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Brugia malayi Thioredoxin reductase 0.0085 0.0443 0.1217
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.0058 0.0295
Echinococcus multilocularis cathepsin b 0.0627 0.3637 0.3634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0117 0.0932
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Trypanosoma brucei hypothetical protein, conserved 0.0211 0.119 0.9364
Loa Loa (eye worm) fibroinase 0.0094 0.05 0.1375
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0205 0.02
Schistosoma mansoni hypothetical protein 0.0082 0.0429 0.118
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Loa Loa (eye worm) pip kinase 1 0.0013 0.0021 0.0057
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0058 0.0053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0205 0.02
Trypanosoma cruzi cysteine proteinase, putative 0.0094 0.05 0.1371
Entamoeba histolytica hypothetical protein 0.0011 0.0009 0.0054
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0221 0.1288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Onchocerca volvulus 0.002 0.006 0.0386
Brugia malayi cathepsin F-like cysteine proteinase 0.0045 0.0212 0.0581
Brugia malayi Cathepsin L-like precursor 0.0094 0.05 0.1375
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0162
Plasmodium falciparum glutathione reductase 0.0085 0.0443 0.885
Echinococcus multilocularis cathepsin b 0.0627 0.3637 0.3634
Brugia malayi Cathepsin L-like precursor 0.0094 0.05 0.1375
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0165
Giardia lamblia Hypothetical protein 0.0045 0.0212 0.1231
Entamoeba histolytica cysteine protease, putative 0.0045 0.0212 0.1278
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0045 0.0212 0.0581
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Brugia malayi Cathepsin L-like precursor 0.0094 0.05 0.1375
Giardia lamblia Cathepsin L precursor 0.0045 0.0212 0.1231
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.0599 0.1646
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0013 0.0021 0.0165
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.119 0.3268
Onchocerca volvulus 0.0045 0.0212 0.1533
Brugia malayi Cathepsin L-like cysteine proteinase 0.0045 0.0212 0.0581
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0045 0.0212 0.1231
Echinococcus granulosus cathepsin L cysteine proteinase 0.0094 0.05 0.1364
Echinococcus multilocularis RUN 0.002 0.006 0.0055
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0627 0.3637 1
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0005 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0094 0.05 0.2984
Loa Loa (eye worm) hypothetical protein 0.005 0.0237 0.0651
Loa Loa (eye worm) hypothetical protein 0.0162 0.0896 0.2464
Plasmodium vivax unspecified product 0.0045 0.0212 0.423
Brugia malayi Inositol-1 0.0037 0.0161 0.0441
Brugia malayi cathepsin L-like cysteine proteinase 0.0045 0.0212 0.0581
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0117 0.0657
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Trypanosoma cruzi major cysteine proteinase, putative 0.0045 0.0212 0.0576
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0045 0.0212 0.423
Brugia malayi Cytochrome P450 family protein 0.001 0.0005 0.0013
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Plasmodium vivax serine-repeat antigen (SERA) 0.0045 0.0212 0.423
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0085 0.0443 0.3639
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0221 0.0595
Loa Loa (eye worm) CYP4Cod1 0.001 0.0005 0.0013
Toxoplasma gondii thioredoxin reductase 0.0085 0.0443 0.3485
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0168 0.0449
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0164
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0045 0.0212 0.423
Schistosoma mansoni apoptosis regulator bax 0.0082 0.0429 0.118
Giardia lamblia Cathepsin L precursor 0.0045 0.0212 0.1231
Mycobacterium tuberculosis Probable oxidoreductase 0.0214 0.1208 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0317
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Schistosoma mansoni DNA helicase recq5 0.0019 0.0058 0.0157
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0045 0.0212 0.423
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0161 0.0429
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0073
Onchocerca volvulus 0.0094 0.05 0.3716
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0029 0.0117 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0058 0.0157
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0058 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0045 0.0212 0.1231
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.01 0.122
Echinococcus multilocularis cathepsin L 0.0094 0.05 0.0496
Plasmodium falciparum replication factor C subunit 1, putative 0.0011 0.0009 0.0173
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0058 0.0295
Brugia malayi cytochrome P450 0.001 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0119 0.0327
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0013 0.0021 0.0016
Brugia malayi hypothetical protein 0.002 0.006 0.0164
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0088 0.0236
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0045 0.0212 0.423
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0245 0.0672
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0886
Brugia malayi AMP-binding enzyme family protein 0.0026 0.01 0.0273
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0164
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0161 0.0971
Brugia malayi cathepsin F-like cysteine proteinase 0.0049 0.0233 0.0641
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0045 0.0212 0.1231
Toxoplasma gondii cathepsin CPC2 0.0045 0.0212 0.1666
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0188 0.1477
Giardia lamblia PHD finger protein 15 0.0029 0.0115 0.0645
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0088 0.1069
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0045 0.0212 0.0581
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0127
Giardia lamblia Cathepsin B precursor 0.0045 0.0212 0.1231
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0054 0.0408
Entamoeba histolytica serine/threonine protein kinase, putative 0.0094 0.05 0.3022
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0119 0.0114
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0081 0.0635
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0009 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0045 0.0212 0.1231
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0193 0.1081 0.8946
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Entamoeba histolytica cysteine protease, putative 0.0045 0.0212 0.1278
Brugia malayi RNA binding protein 0.0133 0.073 0.2007
Echinococcus granulosus fructose 16 bisphosphatase 1 0.0157 0.0868 0.2375
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.01 0.0786
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0002 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Entamoeba histolytica hypothetical protein 0.0036 0.0155 0.0937
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0094 0.05 1
Schistosoma mansoni lipoxygenase 0.0055 0.0268 0.0735
Giardia lamblia Cysteine protease 0.0045 0.0212 0.1231
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0011 0.0009 0.005
Schistosoma mansoni hypothetical protein 0.002 0.006 0.0164
Giardia lamblia Cathepsin B precursor 0.0225 0.1271 0.7663
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0119 0.0114
Plasmodium vivax vivapain-1 0.0094 0.05 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0058 0.0453
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0045 0.0212 0.1231
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0045 0.0212 0.1231
Plasmodium falciparum phd finger protein, putative 0.0029 0.0115 0.2298
Schistosoma mansoni fructose-16-bisphosphatase-related 0.0157 0.0868 0.2385
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0781 0.6445
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0088 0.0655
Echinococcus granulosus expressed conserved protein 0.0103 0.055 0.15
Onchocerca volvulus 0.0094 0.05 0.3716
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0212 0.1231
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0049 0.0233 0.0641
Toxoplasma gondii PHD-finger domain-containing protein 0.0009 0 0.0003
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0225 0.1271 0.3491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0117 0.0112
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0115 0.2303
Loa Loa (eye worm) glutathione reductase 0.0085 0.0443 0.1217
Brugia malayi cathepsin B-like cysteine proteinase 0.0627 0.3637 1
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0117 0.0657
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0119 0.0327
Plasmodium falciparum serine repeat antigen 4 0.0045 0.0212 0.4226
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0013 0.0021 0.0073
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0011 0.0009 0.0071
Treponema pallidum fructose-bisphosphate aldolase 0.029 0.1656 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0058 0.0453
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.05 0.1375
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0045 0.0212 0.423
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0045 0.0212 0.1231
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0061 0.4758
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Schistosoma mansoni patched 1 0.0047 0.0221 0.0607
Giardia lamblia Cathepsin B precursor 0.0045 0.0212 0.1231
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0117 0.0309
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0045 0.0212 0.0581
Schistosoma mansoni inositol monophosphatase 0.0037 0.0161 0.0441
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0245 0.0672
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.0436
Toxoplasma gondii fructose-bisphospatase II 0.0157 0.0868 0.6826
Loa Loa (eye worm) FYVE zinc finger family protein 0.0013 0.0021 0.0057
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.01 0.0786
Trypanosoma cruzi cysteine peptidase, putative 0.0094 0.05 0.1371
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0161 0.0922
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0641
Plasmodium falciparum serine repeat antigen 6 0.0045 0.0212 0.4226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Brugia malayi glutathione reductase 0.0085 0.0443 0.1217
Brugia malayi hypothetical protein 0.002 0.006 0.0164
Brugia malayi Cytochrome P450 family protein 0.001 0.0005 0.0013
Entamoeba histolytica cysteine protease, putative 0.0045 0.0212 0.1278
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0.0009 0.0024
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0045 0.0212 0.0581
Giardia lamblia Cathepsin B precursor 0.0225 0.1271 0.7663
Giardia lamblia Cathepsin B precursor 0.0225 0.1271 0.7663
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.05 0.2983
Schistosoma mansoni cathepsin C 0.0045 0.0212 0.0581
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0045 0.0212 0.0581
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0088 0.1069
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0119 0.0939
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Trypanosoma cruzi cysteine protease, putative 0.0094 0.05 0.1371
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0058 0.0295
Entamoeba histolytica hypothetical protein 0.0045 0.0212 0.1278
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0205 0.0552
Onchocerca volvulus 0.0094 0.05 0.3716
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0162 0.0896 0.2464
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0331 0.2575
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0117 0.0317
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.01 0.0747
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0081 0.6695
Plasmodium falciparum cysteine proteinase falcipain 1 0.0094 0.05 1
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0161 0.1265
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0138 0.1106
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0331 0.0898
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.05 0.2983
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0245 0.1431
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0013 0.0021 0.0052
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0082 0.0429 0.1168
Brugia malayi serine/threonine-protein kinase plk-2 0.0094 0.05 0.1375
Toxoplasma gondii cathepsin B 0.0225 0.1271 1
Echinococcus granulosus tar DNA binding protein 0.0133 0.073 0.1996
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0005
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0193 0.1081 0.8946
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0652 0.1792
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0094 0.05 0.2984
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0273
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0245 0.024
Trypanosoma cruzi cysteine peptidase, putative 0.0094 0.05 0.1371
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0193 0.1081 0.8946
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.1656 1
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0013 0.0021 0.0125
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0652 0.8345
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0061 0.1203
Plasmodium falciparum serine repeat antigen 8 0.0045 0.0212 0.4226
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0431 0.0426
Toxoplasma gondii fructose-bisphospatase I 0.0058 0.0288 0.2265
Schistosoma mansoni hypothetical protein 0.0082 0.0429 0.118
Echinococcus granulosus thioredoxin glutathione reductase 0.0085 0.0446 0.1214
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0162 0.0896 0.2464
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0331 0.0909
Giardia lamblia Fructose-bisphosphate aldolase 0.029 0.1656 1
Leishmania major cysteine peptidase A (CPA) 0.0094 0.05 0.3913
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0081 0.0641
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0155 0.015
Giardia lamblia Cathepsin L-like protease 0.0045 0.0212 0.1231
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0054 0.0408
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.058
Plasmodium falciparum serine repeat antigen 3 0.0045 0.0212 0.4226
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0641
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0781 1
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0058 0.0288 0.0786
Onchocerca volvulus Cathepsin L homolog 0.0094 0.05 0.3716
Echinococcus granulosus cathepsin l1 0.0045 0.0212 0.0569
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.058
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0009 0.0068
Schistosoma mansoni hypothetical protein 0.0082 0.0429 0.118
Brugia malayi AMP-binding enzyme family protein 0.0026 0.01 0.0273
Schistosoma mansoni tar DNA-binding protein 0.0133 0.073 0.2007
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0082 0.0429 0.0425
Giardia lamblia Cathepsin L-like protease 0.0045 0.0212 0.1231
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0589 0.1619
Onchocerca volvulus 0.0162 0.0896 0.6709
Onchocerca volvulus 0.0026 0.01 0.0686
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0331 0.0909
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0094 0.05 0.1375
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0094 0.05 0.1371
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0117 0.0321
Echinococcus multilocularis cysteine protease 0.0094 0.05 0.0496
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0081 0.0603
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0245 0.1893
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0024
Brugia malayi Cathepsin L-like precursor 0.0045 0.0212 0.0581
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0771 0.212
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0245 0.0667
Onchocerca volvulus 0.0015 0.0035 0.0199
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Brugia malayi Cathepsin L-like precursor 0.0094 0.05 0.1375
Brugia malayi RNA recognition motif domain containing protein 0.0133 0.073 0.2007
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0161 0.2008
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0058 0.1145
Schistosoma mansoni rab6-interacting 0.002 0.006 0.0164
Plasmodium vivax thioredoxin reductase, putative 0.0085 0.0443 0.885
Schistosoma mansoni cathepsin S (C01 family) 0.0045 0.0212 0.0581
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0081 0.0985
Trypanosoma cruzi cysteine proteinase, putative 0.0094 0.05 0.1371
Entamoeba histolytica hypothetical protein 0.0036 0.0155 0.0937
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0009 0 0.0003
Toxoplasma gondii preprocathepsin c precursor, putative 0.0045 0.0212 0.1666
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0303 0.0298
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Trypanosoma cruzi cysteine peptidase, putative 0.0094 0.05 0.1371
Loa Loa (eye worm) hypothetical protein 0.0094 0.05 0.1375
Echinococcus granulosus Niemann Pick C1 protein 0.0156 0.0865 0.2369
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0021 0.0052
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0081 0.0641
Giardia lamblia Kinase, PLK 0.0094 0.05 0.2983
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.05 0.1371
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.01 0.0747
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0225 0.1271 0.7663
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0088 0.0228
Loa Loa (eye worm) RNA binding protein 0.0133 0.073 0.2007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0317
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0094 0.05 0.0496
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0054 0.0408
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Loa Loa (eye worm) hypothetical protein 0.0049 0.0233 0.0641
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0009 0.0000020932
Schistosoma mansoni tar DNA-binding protein 0.0133 0.073 0.2007
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Echinococcus multilocularis thioredoxin glutathione reductase 0.0085 0.0446 0.0441
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0.0009 0.0024
Echinococcus multilocularis expressed conserved protein 0.0103 0.055 0.0545
Giardia lamblia Cysteine protease 0.0045 0.0212 0.1231
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0303 0.0832
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0117 0.2343
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0245 0.1431
Brugia malayi Papain family cysteine protease containing protein 0.0094 0.05 0.1375
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Loa Loa (eye worm) ctsf protein 0.0094 0.05 0.1375
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0221 0.1288
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0155 0.0413
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.1163 0.3198
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0045 0.0212 0.0581
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0504 0.0499
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0117 0.0886
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0117 0.1446
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0331 0.2603
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0117 0.0923
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0013 0.0021 0.0057
Entamoeba histolytica cysteine protease, putative 0.0045 0.0212 0.1278
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.012 0.0652 0.5112
Onchocerca volvulus 0.0094 0.05 0.3716
Mycobacterium ulcerans hypothetical protein 0.0024 0.0088 0.1069
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0268 0.0263
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Entamoeba histolytica cysteine proteinase 2 0.0094 0.05 0.3022
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0058 0.0157
Entamoeba histolytica cysteine proteinase, putative 0.0094 0.05 0.3022
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0589 0.1608
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1332 0.803
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0157 0.0868 0.2381
Trypanosoma brucei cysteine peptidase C (CPC) 0.0225 0.1271 1
Giardia lamblia Cathepsin B precursor 0.0045 0.0212 0.1231
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0013 0.0021 0.0125
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0157
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0045 0.0212 0.423
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0168 0.0163
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0245 0.1925
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0221 0.1288
Onchocerca volvulus 0.0094 0.05 0.3716
Brugia malayi Bromodomain containing protein 0.0032 0.0136 0.0372
Treponema pallidum DNA ligase (lig) 0.0011 0.0009 0.0041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0151 0.0415
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.012 0.0652 0.0647
Brugia malayi Cathepsin L-like precursor 0.0049 0.0233 0.0641
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0013 0.0021 0.0052
Onchocerca volvulus Cathepsin F homolog 0.0094 0.05 0.3716
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0389 0.1068
Brugia malayi Papain family cysteine protease containing protein 0.0045 0.0212 0.0581
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0117 0.092
Brugia malayi Pip kinase protein 2 0.0162 0.0896 0.2464
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0781 0.6445
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0431 0.1174
Onchocerca volvulus 0.0094 0.05 0.3716
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0624 0.1715
Schistosoma mansoni tar DNA-binding protein 0.0133 0.073 0.2007
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0188 0.0503
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0652 0.8345
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0188 0.375
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0303 0.3842
Schistosoma mansoni cathepsin F (C01 family) 0.0094 0.05 0.1375
Plasmodium vivax unspecified product 0.0049 0.0233 0.4662
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0013 0.0021 0.0165
Brugia malayi fructose-1,6-bisphosphatase 0.0157 0.0868 0.2385
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0052
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0771 0.212
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0094 0.05 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0193 0.1081 0.8946
Onchocerca volvulus 0.0045 0.0212 0.1533
Trypanosoma cruzi cysteine peptidase, putative 0.0094 0.05 0.1371
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0117 0.1446
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0115 0.0907
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0117 0.0657
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0013 0.0021 0.0162
Brugia malayi AMP-binding enzyme family protein 0.0026 0.01 0.0273
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0013 0.0021 0.0044
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Toxoplasma gondii cytochrome p450 superfamily protein 0.001 0.0005 0.004
Echinococcus granulosus nibrin 0.0011 0.0009 0.0011
Echinococcus granulosus cysteine protease 0.0094 0.05 0.1364
Schistosoma mansoni rab6-interacting 0.002 0.006 0.0164
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0088 0.048
Treponema pallidum NADH oxidase 0.0029 0.0117 0.0696
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0167 0.0962
Schistosoma mansoni loxhd1 0.002 0.006 0.0164
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0258 0.0708
Giardia lamblia Cathepsin L precursor 0.0045 0.0212 0.1231
Loa Loa (eye worm) cathepsin B 0.0225 0.1271 0.3494
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.0157 0.0868 0.2385
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0009 0.0011
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0002 0.0017
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0589 0.0584
Trypanosoma cruzi cytochrome p450-like protein, putative 0.001 0.0005 0.0008
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0045 0.0212 0.0576
Plasmodium falciparum serine repeat antigen 2 0.0045 0.0212 0.4226
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0205 0.0564
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0245 0.1431
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0005
Echinococcus granulosus bloom syndrome protein 0.0019 0.0058 0.0145
Brugia malayi Pre-SET motif family protein 0.003 0.0119 0.0327
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0088 0.0689
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0045 0.0212 0.0581
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0317
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0117 0.0923
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0013 0.0021 0.0165
Toxoplasma gondii cathepsin CPC1 0.0045 0.0212 0.1666
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0088 0.1069
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.01 0.0602
Brugia malayi hypothetical protein 0.0036 0.0155 0.0426
Schistosoma mansoni cathepsin B (C01 family) 0.0045 0.0212 0.0581
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.05 0.2983
Entamoeba histolytica cysteine proteinase, putative 0.0094 0.05 0.3022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0205 0.0552
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0094 0.05 0.1375
Leishmania major 0.0157 0.0868 0.6814
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0225 0.1271 0.3494
Toxoplasma gondii cathepsin CPL 0.0094 0.05 0.3937
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0081 0.0985
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0151 0.0402
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0627 0.3637 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0094 0.05 0.0496
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0009 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.119 0.3268
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0005 0.0008
Brugia malayi Pip kinase protein 1 0.0013 0.0021 0.0057
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0058 0.0451
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0045 0.0212 0.0581
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0082 0.0429 0.118
Brugia malayi hypothetical protein 0.0011 0.0009 0.0024
Brugia malayi jmjC domain containing protein 0.0095 0.0504 0.1384
Giardia lamblia Hypothetical protein 0.0013 0.0021 0.0073
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.001 0.0005 0.0037
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0119 0.0327
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0045 0.0212 0.4226
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0045 0.0212 0.0581
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.01 0.122
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.006 0.0151
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0221 0.0607
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0245 0.0667
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0024
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0431 0.1185
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.05 0.2983
Entamoeba histolytica hypothetical protein 0.0023 0.0081 0.0492
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0117 0.092
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.1263
Loa Loa (eye worm) pip kinase 2 0.0162 0.0896 0.2464
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0045 0.0212 0.4226
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0212 0.1231
Echinococcus granulosus cathepsin L 0.0045 0.0212 0.0569
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.05 0.2983
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0162 0.0896 0.0892
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0245 0.066
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0162 0.0896 0.2454
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.05 0.1371
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0115 0.0303
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0058 0.0157
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0165
Schistosoma mansoni cytochrome P450 0.001 0.0005 0.0013
Brugia malayi DKFZp564C0469 protein 0.0011 0.0009 0.0024
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.01 0.0786
Brugia malayi Cathepsin L-like precursor 0.0094 0.05 0.1375
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0054 0.0408
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0088 0.0083
Trypanosoma cruzi FHA domain containing protein, putative 0.0011 0.0009 0.0019
Echinococcus granulosus RUN 0.002 0.006 0.0151
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0094 0.05 0.1375
Brugia malayi Cathepsin L-like precursor 0.0045 0.0212 0.0581
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0115 0.0907
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0045 0.0212 0.0581
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Entamoeba histolytica cysteine proteinase, putative 0.0094 0.05 0.3022
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0045 0.0212 0.423
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0233 0.0636
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0094 0.05 0.3022
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0162
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0188 0.1477
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.006 0.0055
Brugia malayi cathepsin L-like precursor 0.0045 0.0212 0.0581
Schistosoma mansoni kinase 0.0048 0.0228 0.0627
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0058 0.1145
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.01 0.0602
Brugia malayi cathepsin L precursor 0.0045 0.0212 0.0581
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0117 0.2338
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0058 0.0348
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0082 0.0429 0.118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0331 0.1999
Echinococcus multilocularis bloom syndrome protein 0.0019 0.0058 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0117 0.0317
Giardia lamblia Hypothetical protein 0.0045 0.0212 0.1231
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Giardia lamblia Encystation-specific protease 0.0045 0.0212 0.1231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Echinococcus granulosus peregrin 0.0032 0.0136 0.0359
Brugia malayi Doublecortin family protein 0.002 0.006 0.0164
Trypanosoma brucei protein kinase, putative 0.0051 0.0245 0.1923
Plasmodium vivax vivapain-2 0.0094 0.05 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0094 0.05 0.1375
Loa Loa (eye worm) hypothetical protein 0.0082 0.0429 0.118
Entamoeba histolytica cysteine proteinase, putative 0.0045 0.0212 0.1278
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0011 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0083 0.0431 0.1185
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0117 0.713
Trypanosoma cruzi cruzipain precursor, putative 0.0094 0.05 0.1371
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.01 0.122
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0094 0.05 0.1364
Onchocerca volvulus 0.002 0.006 0.0386
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.01 0.122
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0331 0.0326
Schistosoma mansoni hypothetical protein 0.0029 0.0115 0.0316
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0082 0.0429 0.1168
Echinococcus granulosus cathepsin L cysteine protease 0.0094 0.05 0.1364
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0045 0.0212 0.1231
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0504 0.1373
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0188 0.1085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0045 0.0212 0.0581
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0013 0.0021 0.0052
Mycobacterium tuberculosis Probable reductase 0.0193 0.1081 0.8946
Schistosoma mansoni inositol monophosphatase 0.0037 0.0161 0.0441
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0013 0.0021 0.0162
Echinococcus multilocularis protein patched 0.0047 0.0221 0.0216
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0161 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0165
Trypanosoma cruzi trypanothione reductase, putative 0.0085 0.0443 0.1213
Entamoeba histolytica phosphoinositide kinase, putative 0.0013 0.0021 0.0127
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0061 0.046
Schistosoma mansoni cathepsin F (C01 family) 0.0045 0.0212 0.0581
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0058 0.0295
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0115 0.011
Brugia malayi Papain family cysteine protease containing protein 0.0045 0.0212 0.0581
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0045 0.0212 0.1231
Brugia malayi Cytochrome P450 family protein 0.0047 0.0223 0.0612
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0094 0.05 0.3912
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0081 0.1622
Plasmodium falciparum thioredoxin reductase 0.0029 0.0117 0.2338
Plasmodium vivax serine-repeat antigen (SERA) 0.0045 0.0212 0.423
Schistosoma mansoni lipoxygenase 0.002 0.006 0.0164
Giardia lamblia Cathepsin L precursor 0.0045 0.0212 0.1231
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0297 0.0816
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0094 0.05 0.1375
Schistosoma mansoni DNA ligase IV 0.0011 0.0009 0.0024
Plasmodium falciparum thioredoxin reductase 0.0085 0.0443 0.885
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0431 0.1185
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0013 0.0021 0.0057
Echinococcus multilocularis cathepsin L cysteine protease 0.0094 0.05 0.0496
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0165
Schistosoma mansoni topbp1 0.0011 0.0009 0.0024
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.01 0.0786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Loa Loa (eye worm) cysteine protease 0.0094 0.05 0.1375
Brugia malayi Papain family cysteine protease containing protein 0.0094 0.05 0.1375
Brugia malayi Papain family cysteine protease containing protein 0.0045 0.0212 0.0581
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0245 0.024
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0193 0.1081 0.8946
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0045 0.0212 0.1231
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0013 0.0021 0.0052
Onchocerca volvulus Cathepsin L homolog 0.0045 0.0212 0.1533
Loa Loa (eye worm) cytochrome P450 0.001 0.0005 0.0013
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0303 0.0832
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0205 0.0564
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0117 0.713
Giardia lamblia Cathepsin B precursor 0.0045 0.0212 0.1231
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.0058 0.0288 0.2265
Entamoeba histolytica recQ family DNA helicase 0.001 0.0002 0.0013
Echinococcus multilocularis cysteine protease 0.0094 0.05 0.0496
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0155 0.0426
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0117 0.0886
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0245 0.1431
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0331 0.0905
Plasmodium vivax vivapain-3 0.0094 0.05 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0094 0.05 0.3936
Trypanosoma brucei polo-like protein kinase 0.0094 0.05 0.3935
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.1656 1
Plasmodium vivax hypothetical protein, conserved 0.0009 0 0.0007
Brugia malayi TAR-binding protein 0.0133 0.073 0.2007
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0009 0.0000020932
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0188 0.1085
Trypanosoma brucei fructose-1,6-bisphosphatase 0.0157 0.0868 0.6826
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0081 0.0635
Toxoplasma gondii aldehyde dehydrogenase 0.012 0.0652 0.5131
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0045 0.0212 0.1231
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0115 0.0316
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0081 0.4774
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0071 0.0195
Echinococcus multilocularis tar DNA binding protein 0.0133 0.073 0.0725
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.05 0.2983
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0214 0.1208 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.01 0.122
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Plasmodium vivax SET domain protein, putative 0.003 0.0119 0.2385
Plasmodium vivax unspecified product 0.0094 0.05 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0045 0.0212 0.0581
Brugia malayi jmjC domain containing protein 0.0035 0.0151 0.0415
Leishmania major trypanothione reductase 0.0085 0.0443 0.3458
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0013 0.0021 0.0125
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0273
Mycobacterium tuberculosis Conserved protein 0.0024 0.0088 0.0689
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0045 0.0212 0.423
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0117 0.2343
Echinococcus granulosus cathepsin L 0.0094 0.05 0.1364
Entamoeba histolytica hypothetical protein 0.0036 0.0155 0.0937
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0627 0.3637 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0221 0.0216
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0045 0.0212 0.1278
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0119 0.0327
Echinococcus granulosus jumonji domain containing protein 0.004 0.0182 0.0487
Onchocerca volvulus Serine\/threonine kinase homolog 0.0094 0.05 0.3715
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.012 0.0652 0.5378
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0002 0.0044
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0013 0.0021 0.0057
Loa Loa (eye worm) hypothetical protein 0.0627 0.3637 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0071 0.0195
Onchocerca volvulus 0.0094 0.05 0.3716
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0013 0.0021 0.0057
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Plasmodium falciparum serine repeat antigen 7 0.0045 0.0212 0.4226
Echinococcus granulosus cathepsin l1 0.0094 0.05 0.1364
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0058 0.0053
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0303 0.2354
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0052
Brugia malayi Papain family cysteine protease containing protein 0.0094 0.05 0.1375
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0024
Giardia lamblia Cathepsin B precursor 0.0045 0.0212 0.1231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0094 0.05 0.2984
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0233 0.0641
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0223 0.0612
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.0058 0.0288 0.2262
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0212 0.1231
Loa Loa (eye worm) acetyltransferase 0.014 0.0771 0.212
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0094 0.05 0.0495
Plasmodium falciparum glutathione reductase 0.0029 0.0117 0.2338
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0221 0.0595
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0081 0.1628
Echinococcus multilocularis Niemann Pick C1 protein 0.0156 0.0865 0.0861
Loa Loa (eye worm) hypothetical protein 0.0058 0.0283 0.0778
Schistosoma mansoni polycystin 1-related 0.002 0.006 0.0164
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0045 0.0212 0.1231
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0045 0.0212 0.0581
Brugia malayi topoisomerase 0.0011 0.0009 0.0024
Onchocerca volvulus Cathepsin L homolog 0.0094 0.05 0.3716
Echinococcus multilocularis cathepsin L 0.0045 0.0212 0.0207
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0119 0.0315
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0331 0.0909
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.012 0.0652 0.1782
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0748 0.2046
Loa Loa (eye worm) thioredoxin reductase 0.0085 0.0443 0.1217
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0589 0.3557
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.0624 0.1715
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.0157 0.0868 0.2381
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0303 0.3842
Plasmodium falciparum cysteine proteinase falcipain 3 0.0094 0.05 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0167 0.1011
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0045 0.0212 0.423
Echinococcus granulosus cathepsin b 0.0627 0.3637 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0161 0.0436
Giardia lamblia Cathepsin L precursor 0.0045 0.0212 0.1231
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0581
Entamoeba histolytica cysteine proteinase, putative 0.0094 0.05 0.3022
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0182 0.0177
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022
Plasmodium vivax vivapain-2 0.0094 0.05 1
Entamoeba histolytica cysteine protease, putative 0.0045 0.0212 0.1278
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0117 0.2338
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0013 0.0021 0.0057
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0245 0.066
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0627 0.3637 1
Schistosoma mansoni topbp1 0.0011 0.0009 0.0024
Plasmodium falciparum LCCL domain-containing protein 0.002 0.006 0.1193
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0094 0.05 0.2984
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0009 0.0019
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0245 0.0667
Schistosoma mansoni tar DNA-binding protein 0.0133 0.073 0.2007
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0088 0.0236
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0061 0.0714
Brugia malayi Pre-SET motif family protein 0.0207 0.1163 0.3198
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0117 0.0321
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0652 0.1792
Leishmania major cathepsin L-like protease 0.0094 0.05 0.3913
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0214 0.1208 1
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.0157 0.0868 0.0863
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0303 0.082
Mycobacterium ulcerans hypothetical protein 0.0026 0.01 0.122
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0117 0.092
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0094 0.05 0.1375
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0245 0.1893
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0268 0.0723
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.01 0.0602
Echinococcus granulosus cathepsin l cysteine peptidase 0.0094 0.05 0.1364
Loa Loa (eye worm) apoptosis regulator protein 0.0082 0.0429 0.118
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0117 0.1446
Brugia malayi CHE-14 protein 0.0047 0.0221 0.0607
Onchocerca volvulus 0.0083 0.0431 0.3194
Schistosoma mansoni cathepsin F (C01 family) 0.0094 0.05 0.1375
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0167 0.3341
Echinococcus multilocularis cathepsin L cysteine protease 0.0094 0.05 0.0496
Loa Loa (eye worm) doublecortin family protein 0.002 0.006 0.0164
Trypanosoma brucei cytochrome P450, putative 0.001 0.0005 0.0037
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0013 0.0021 0.0057
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0009 0.0019
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0009 0.0000020932
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0013 0.0021 0.0052
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0205 0.0564
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0205 0.0564
Brugia malayi MH2 domain containing protein 0.0115 0.0624 0.1715
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1656 1
Schistosoma mansoni DNA helicase recq1 0.0019 0.0058 0.0157
Onchocerca volvulus 0.003 0.0119 0.0834
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0151 0.0415
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0007 0.0018
Entamoeba histolytica cysteine protease, putative 0.0094 0.05 0.3022

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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