Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.1007 | 1 | 1 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0145 | 0.0145 |
Brugia malayi | Choline O-acetyltransferase | 0.0176 | 0.1682 | 0.1682 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0145 | 0.0145 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.001 | 0.0029 | 0.0148 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.008 | 0.008 |
Schistosoma mansoni | choline o-acyltransferase | 0.0176 | 0.1682 | 0.1682 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.0005 | 0.0005 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0026 | 0.0187 | 0.3548 |
Brugia malayi | MH2 domain containing protein | 0.0111 | 0.1035 | 0.1035 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.017 | 0.1627 | 0.1627 |
Echinococcus granulosus | acetylcholinesterase | 0.1007 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.017 | 0.1627 | 0.1627 |
Onchocerca volvulus | 0.0026 | 0.0187 | 0.0989 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.008 | 0.008 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1007 | 1 | 1 |
Onchocerca volvulus | 0.017 | 0.1627 | 1 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0145 | 0.148 |
Echinococcus granulosus | neuroligin | 0.017 | 0.1627 | 0.1627 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1007 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Brugia malayi | Cathepsin L-like precursor | 0.001 | 0.0029 | 0.0029 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.017 | 0.1627 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.008 | 0.008 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.008 | 0.008 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.008 | 0.008 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0176 | 0.1682 | 0.1682 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0029 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0022 | 0.0145 | 0.0363 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0026 | 0.0187 | 0.3548 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0016 | 0.0089 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.008 | 0.008 |
Toxoplasma gondii | cathepsin CPL | 0.0016 | 0.008 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0089 | 0.0089 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.008 | 0.0322 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Schistosoma mansoni | gliotactin | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0029 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0008 | 0.0005 | 0.0005 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.017 | 0.1627 | 0.1627 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0518 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0016 | 0.008 | 0.8932 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0026 | 0.0187 | 0.0187 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.017 | 0.1627 | 0.1627 |
Onchocerca volvulus | 0.0016 | 0.008 | 0.0322 | |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 0.1682 | 0.1682 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.0518 | 1 |
Onchocerca volvulus | 0.017 | 0.1627 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0008 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | carboxylesterase | 0.017 | 0.1627 | 0.1627 |
Echinococcus granulosus | BC026374 protein S09 family | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0089 | 0.0089 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Brugia malayi | Cathepsin L-like precursor | 0.001 | 0.0029 | 0.0029 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.008 | 0.008 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0059 | 0.0518 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.008 | 0.008 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.008 | 0.008 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0026 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1007 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.008 | 0.008 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.008 | 0.008 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0111 | 0.1035 | 0.1035 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0187 | 0.3548 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0008 | 0.0005 | 0.0005 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.017 | 0.1627 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0022 | 0.0145 | 0.5 |
Onchocerca volvulus | 0.0022 | 0.0145 | 0.0728 | |
Onchocerca volvulus | 0.0016 | 0.008 | 0.0322 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0026 | 0.0187 | 0.0187 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.0518 | 1 |
Echinococcus granulosus | cathepsin L | 0.0008 | 0.0005 | 0.0005 |
Onchocerca volvulus | 0.0026 | 0.0187 | 0.0989 | |
Brugia malayi | cathepsin L-like precursor | 0.001 | 0.0029 | 0.0029 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0016 | 0.0089 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Echinococcus granulosus | acetylcholinesterase | 0.1007 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.1007 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1007 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1007 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.017 | 0.1627 | 0.1627 |
Entamoeba histolytica | cysteine protease, putative | 0.0016 | 0.008 | 0.5383 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0145 | 0.0145 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0016 | 0.0089 | 0.0058 |
Brugia malayi | Carboxylesterase family protein | 0.017 | 0.1627 | 0.1627 |
Onchocerca volvulus | 0.0016 | 0.008 | 0.0322 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.001 | 0.0029 | 0.0029 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0518 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0026 | 0.0187 | 0.0187 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.008 | 0.5383 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.008 | 0.8932 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0054 | 0.0466 | 0.8997 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Onchocerca volvulus | 0.0016 | 0.008 | 0.0322 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0145 | 0.0145 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0026 | 0.0187 | 0.0187 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0518 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.0005 | 0.0005 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.017 | 0.1627 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0022 | 0.0145 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.017 | 0.1627 | 0.1627 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0145 | 0.0363 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0022 | 0.0145 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Echinococcus multilocularis | neuroligin | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.008 | 0.008 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0016 | 0.008 | 0.8932 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.017 | 0.1627 | 0.1627 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.017 | 0.1627 | 0.1627 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0026 | 0.0187 | 0.0187 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0026 | 0.0187 | 0.0187 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0187 | 0.0187 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Echinococcus granulosus | carboxylesterase 5A | 0.1007 | 1 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0022 | 0.0145 | 0.0363 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0026 | 0.0187 | 0.3548 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.008 | 0.008 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0111 | 0.1035 | 0.1035 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.008 | 0.008 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.008 | 0.008 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.008 | 0.008 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.001 | 0.0029 | 0.0148 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0145 | 0.148 |
Brugia malayi | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0029 | 0.0029 |
Entamoeba histolytica | cysteine proteinase, putative | 0.001 | 0.0029 | 0.1713 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.008 | 0.8932 |
Loa Loa (eye worm) | carboxylesterase | 0.017 | 0.1627 | 0.1627 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Onchocerca volvulus | 0.0016 | 0.008 | 0.0322 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.017 | 0.1627 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.008 | 0.008 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0089 | 0.0089 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0145 | 0.0363 |
Onchocerca volvulus | 0.0016 | 0.008 | 0.0322 | |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.001 | 0.0029 | 0.0029 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0022 | 0.0145 | 0.0363 |
Brugia malayi | Carboxylesterase family protein | 0.017 | 0.1627 | 0.1627 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Onchocerca volvulus | 0.017 | 0.1627 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.017 | 0.1627 | 0.1627 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0022 | 0.0145 | 0.0363 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0026 | 0.0187 | 0.0187 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0022 | 0.0145 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.008 | 0.008 |
Onchocerca volvulus | 0.0026 | 0.0187 | 0.0989 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0022 | 0.0145 | 1 |
Onchocerca volvulus | 0.017 | 0.1627 | 1 | |
Echinococcus multilocularis | choline O acetyltransferase | 0.0176 | 0.1682 | 0.1682 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Echinococcus granulosus | cysteine protease | 0.0008 | 0.0005 | 0.0005 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.008 | 0.5383 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0016 | 0.008 | 0.1472 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0026 | 0.0187 | 0.0187 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0145 | 0.0145 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0022 | 0.0145 | 1 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0026 | 0.0187 | 0.2435 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.017 | 0.1627 | 0.1627 |
Echinococcus granulosus | cathepsin l1 | 0.001 | 0.0029 | 0.0029 |
Schistosoma mansoni | acetylcholinesterase | 0.017 | 0.1627 | 0.1627 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0145 | 0.0419 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.017 | 0.1627 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Schistosoma mansoni | choline o-acyltransferase | 0.0026 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0016 | 0.0089 | 1 |
Onchocerca volvulus | 0.0016 | 0.008 | 0.0322 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.008 | 0.008 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Onchocerca volvulus | Cathepsin F homolog | 0.0016 | 0.008 | 0.0322 |
Onchocerca volvulus | 0.017 | 0.1627 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0016 | 0.008 | 0.8932 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0026 | 0.0187 | 0.2435 |
Echinococcus multilocularis | acetylcholinesterase | 0.1007 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0145 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0089 | 0.0089 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0022 | 0.0145 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0089 | 0.0089 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.008 | 0.008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0187 | 0.3548 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0026 | 0.0187 | 0.3548 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0008 | 0.0005 | 0.0005 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0026 | 0.0187 | 0.3548 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0187 | 0.3548 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Onchocerca volvulus | 0.0026 | 0.0187 | 0.0989 | |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0026 | 0.0187 | 0.2435 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.008 | 0.008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0187 | 0.3548 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0187 | 0.3548 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.008 | 0.0322 |
Brugia malayi | Choline O-acetyltransferase | 0.0176 | 0.1682 | 0.1682 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.008 | 0.008 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0059 | 0.0518 | 1 |
Echinococcus granulosus | choline O acetyltransferase | 0.0176 | 0.1682 | 0.1682 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.017 | 0.1627 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.0005 | 0.0005 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0145 | 0.148 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.1627 | 0.1627 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.0518 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0145 | 0.0145 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.008 | 0.0466 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0047 | 0.0391 | 0.7525 |
Loa Loa (eye worm) | hypothetical protein | 0.1007 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (ADMET) | = 860 nM | Drug level in CD1 mouse brain at 5 mg/kg, ip after 1 hr by LC-MS/MS system | ChEMBL. | 24992153 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.