Detailed information for compound 920209

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 485.327 | Formula: C23H21BrN2O5
  • H donors: 2 H acceptors: 2 LogP: 4.78 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(/C=N\NC(=O)c2ccccc2OCCOc2ccccc2)cc(c1O)Br
  • InChi: 1S/C23H21BrN2O5/c1-29-21-14-16(13-19(24)22(21)27)15-25-26-23(28)18-9-5-6-10-20(18)31-12-11-30-17-7-3-2-4-8-17/h2-10,13-15,27H,11-12H2,1H3,(H,26,28)/b25-15-
  • InChiKey: YXCQTBVDZNMQCW-MYYYXRDXSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0002 0.0005
Brugia malayi Kringle domain containing protein 0.0018 0.0011 0.0032
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0051 0.0049
Brugia malayi Peroxidasin 0.0023 0.0026 0.0082
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0078 0.0257
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0112 0.0295 0.0976
Brugia malayi hypothetical protein 0.0437 0.1275 0.4235
Echinococcus granulosus smad 0.0025 0.0033 0.0071
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0021 0.0021 0.0043
Brugia malayi hypothetical protein 0.0019 0.0015 0.0042
Brugia malayi CBS domain containing protein 0.0021 0.0021 0.0063
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0051 0.0072
Onchocerca volvulus 0.0081 0.0202 0.1387
Brugia malayi Prion-like- 0.0023 0.0026 0.0082
Loa Loa (eye worm) loechrig isoform VII 0.023 0.0651 0.2161
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0039 0.0075 0.0508
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0212 0.0596 0.1979
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0108 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0039 0.0075 0.0241
Echinococcus multilocularis flap endonuclease 1 0.0055 0.0125 0.0123
Echinococcus multilocularis cyclin dependent kinase 0.005 0.0108 0.0106
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0016 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0049 0.0105 0.0346
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0021 0.0063
Onchocerca volvulus 0.0019 0.0015 0.0087
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0078 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.008 0.0263
Leishmania major serine/threonine-protein kinase, putative 0.0022 0.0024 0.0077
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0021 0.0025
Schistosoma mansoni Smad4 0.0025 0.0033 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0051 0.0177
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0269
Trichomonas vaginalis BRCA1-associated protein, putative 0.0019 0.0016 0.0035
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0043 0.0087 0.0197
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0021 0.0021 0.0066
Trypanosoma cruzi GMP reductase 0.0021 0.0021 0.0066
Schistosoma mansoni 3-dehydroquinate synthase 0.0119 0.0317 0.0727
Echinococcus granulosus acetylcholinesterase 0.0479 0.1401 0.3211
Loa Loa (eye worm) hypothetical protein 0.0059 0.0135 0.0447
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0051 0.0163
Plasmodium falciparum serine/threonine protein kinase, putative 0.017 0.0471 0.0675
Entamoeba histolytica serine/threonine protein kinase, putative 0.0049 0.0105 0.0361
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0007 0.0018
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Schistosoma mansoni tar DNA-binding protein 0.0251 0.0715 0.164
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0043 0.0087 0.0125
Loa Loa (eye worm) hypothetical protein 0.0044 0.0092 0.0302
Leishmania major UDP-galactopyranose mutase 0.0043 0.0089 0.0292
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0039 0.0075 0.0508
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0027 0.0087
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0023 0.0026 0.0169
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0066 0.0157 0.0225
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0292
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0024 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Plasmodium falciparum glutathione reductase 0.004 0.0078 0.0108
Echinococcus granulosus microtubule associated protein 2 0.1462 0.4361 1
Echinococcus granulosus Niemann Pick C1 protein 0.044 0.1282 0.2938
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0008 0.0023
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.0619 0.2055
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0306 0.088 0.1244
Echinococcus granulosus histone deacetylase 0.1013 0.3008 0.6898
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0081 0.0202 0.0464
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0078 0.0076
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0238 0.0675 0.2239
Brugia malayi Patched related family protein 10 0.0019 0.0015 0.0042
Entamoeba histolytica Flap nuclease, putative 0.0055 0.0125 0.0442
Trypanosoma cruzi histone deacetylase, putative 0.1013 0.3008 1
Echinococcus granulosus expressed conserved protein 0.0289 0.0829 0.1897
Entamoeba histolytica protein kinase, putative 0.0192 0.0538 0.2108
Schistosoma mansoni coup transcription factor 0.0031 0.0051 0.0117
Leishmania major inosine-5-monophosphate dehydrogenase 0.0021 0.0021 0.0066
Schistosoma mansoni chloride channel protein 0.0021 0.0021 0.0047
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0051 0.0117
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0021 0.0022 0.007
Echinococcus granulosus histone deacetylase 6 0.1013 0.3008 0.6898
Leishmania major guanosine monophosphate reductase 0.0021 0.0021 0.0066
Schistosoma mansoni ap endonuclease 0.0038 0.0074 0.017
Loa Loa (eye worm) hypothetical protein 0.013 0.0351 0.1164
Brugia malayi hypothetical protein 0.0016 0.0007 0.0018
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0021 0.0056
Loa Loa (eye worm) fli-1 protein 0.0221 0.0625 0.2074
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0108 0.0357
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0112 0.0295 0.0974
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.1181
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0043 0.0087 0.0096
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0201
Brugia malayi hypothetical protein 0.0019 0.0015 0.0042
Echinococcus multilocularis geminin 0.0513 0.1503 0.1501
Schistosoma mansoni hypothetical protein 0.0098 0.0254 0.0581
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0025 0.0081
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0016 0.0007 0.0019
Loa Loa (eye worm) chloride channel protein 7 0.0021 0.0021 0.0066
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0081 0.0202 0.0459
Brugia malayi polk-prov protein 0.0094 0.0243 0.0801
Onchocerca volvulus Tyrosine kinase homolog 0.0494 0.1445 1
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.008 0.0179
Trypanosoma brucei unspecified product 0.0171 0.0472 0.1567
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0383 0.1268
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.039 0.1295
Loa Loa (eye worm) hypothetical protein 0.0188 0.0525 0.1742
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0041 0.0082 0.0269
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0007 0.0021
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0022 0.0025 0.0058
Echinococcus multilocularis tar DNA binding protein 0.0251 0.0715 0.0713
Brugia malayi Protein kinase domain containing protein 0.0022 0.0025 0.0079
Brugia malayi conserved hypotetical protein 0.0014 0.0002 0.0001
Echinococcus granulosus muscleblind protein 0.0919 0.2726 0.6249
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0044 0.0042
Plasmodium vivax JmjC domain containing protein 0.0016 0.0008 0.0007
Brugia malayi Niemann-Pick C1 protein precursor 0.0308 0.0885 0.2937
Schistosoma mansoni cell adhesion molecule 0.0023 0.0026 0.0061
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0067 0.0065
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0051 0.0112
Schistosoma mansoni nuclear receptor 0.0014 0.0002 0.0005
Trichomonas vaginalis histone deacetylase, putative 0.0842 0.2493 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.0254 0.084
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0021 0.0066
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0043 0.0087 0.0096
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0058 0.0056
Leishmania major hypothetical protein, conserved 0.0019 0.0016 0.0049
Echinococcus granulosus GPCR family 2 0.0098 0.0254 0.0577
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0043 0.0087 0.0096
Echinococcus multilocularis lachesin 0.0023 0.0026 0.0024
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0023 0.0021
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0383 0.1073
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0615 0.181 0.259
Plasmodium vivax histone deacetylase 2, putative 0.1013 0.3008 0.4339
Brugia malayi Patched protein homolog 1 0.0019 0.0015 0.0042
Loa Loa (eye worm) hypothetical protein 0.0109 0.0287 0.095
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0028 0.006
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0041 0.0082 0.0181
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0146 0.0398 0.1117
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0022 0.0024 0.0077
Loa Loa (eye worm) runx1 0.0055 0.0124 0.0408
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0089 0.0292
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0292
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0025 0.0074
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0055 0.0125 0.0413
Schistosoma mansoni acetylcholinesterase 0.0081 0.0202 0.0464
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.0015 0.0003 0.0003
Echinococcus granulosus histone deacetylase 8 0.0422 0.1228 0.2814
Schistosoma mansoni histone deacetylase 4 5 0.1013 0.3008 0.6899
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0087 0.0221 0.073
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.005 0.0108 0.0244
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0306 0.088 0.1244
Brugia malayi serine/threonine-protein kinase 6 0.017 0.0471 0.1559
Echinococcus multilocularis GPCR, family 2 0.0098 0.0254 0.0252
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0074 0.0271
Schistosoma mansoni hypothetical protein 0.1259 0.375 0.86
Schistosoma mansoni hypothetical protein 0.0018 0.0011 0.0026
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0112 0.0295 0.0974
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0092 0.0208
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0113 0.0373
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Schistosoma mansoni histone deacetylase 0.0842 0.2493 0.5717
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0021 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.061 0.1796 0.5968
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Echinococcus multilocularis casein kinase ii subunit beta 0.0039 0.0075 0.0073
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0021 0.0022 0.0026
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0078 0.0076
Loa Loa (eye worm) TAR-binding protein 0.0251 0.0715 0.2375
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0025 0.0039
Onchocerca volvulus 0.0031 0.0051 0.0339
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Leishmania major hypothetical protein, conserved 0.0112 0.0295 0.0976
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.008 0.0263
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0472 0.1871
Mycobacterium ulcerans hypothetical protein 0.0326 0.0941 0.1332
Chlamydia trachomatis protoporphyrinogen oxidase 0.0043 0.0089 0.0098
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0293 0.0841 0.2793
Treponema pallidum hemolysin (tlyC) 0.0021 0.0021 0.024
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0084 0.0312
Echinococcus granulosus phd:f box containing protein 0.0016 0.0008 0.0013
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.006 0.0139 0.0314
Loa Loa (eye worm) hypothetical protein 0.0081 0.0202 0.0669
Entamoeba histolytica deoxycytidyl transferase, putative 0.013 0.035 0.135
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Echinococcus multilocularis AMPK beta subunit 0.0112 0.0295 0.0293
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0034 0.011
Leishmania major chloride channel protein, putative 0.0021 0.0021 0.0066
Loa Loa (eye worm) flap endonuclease-1 0.0055 0.0125 0.0413
Schistosoma mansoni tyrosine kinase 0.0027 0.0041 0.0093
Plasmodium falciparum histone deacetylase, putative 0.1013 0.3008 0.4339
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0021 0.0019
Brugia malayi hypothetical protein 0.0041 0.0082 0.0266
Loa Loa (eye worm) carboxylesterase 0.0479 0.1401 0.4656
Toxoplasma gondii patched family protein 0.0019 0.0015 0.002
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.0232 0.0625
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0025 0.0023
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0272 0.0778 0.0777
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0118 0.0271
Echinococcus multilocularis roundabout 2 0.0023 0.0026 0.0024
Echinococcus multilocularis Niemann Pick C1 protein 0.0308 0.0885 0.0883
Trypanosoma brucei chrX additional, unordered contigs 0.004 0.008 0.0263
Trypanosoma brucei histone deacetylase, putative 0.1013 0.3008 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0021
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0192 0.0272
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.017 0.0471 0.1836
Schistosoma mansoni histone deacetylase hda2 0.0422 0.1228 0.2817
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0741 0.2954
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0051 0.0049
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0051 0.0166
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0008 0.0013
Brugia malayi MH2 domain containing protein 0.0025 0.0033 0.0103
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0002 0.0001
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0113 0.0162
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0043 0.0087 0.0122
Brugia malayi CXXC zinc finger family protein 0.0088 0.0225 0.0741
Echinococcus granulosus nibrin 0.0041 0.0082 0.0183
Trypanosoma brucei histone deacetylase 2 0.0422 0.1228 0.4081
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.03 0.0996
Schistosoma mansoni hypothetical protein 0.0127 0.0342 0.0783
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0225 0.0744
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Brugia malayi RNA recognition motif domain containing protein 0.0251 0.0715 0.2373
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0051 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0051 0.0163
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0571 0.1679 0.4915
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Loa Loa (eye worm) Smad1 0.0025 0.0033 0.0106
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Trypanosoma brucei DNA polymerase IV, putative 0.0184 0.0513 0.1702
Leishmania major 4-coumarate:coa ligase-like protein 0.0146 0.0398 0.1319
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0019 0.0016 0.0018
Echinococcus granulosus twitchin 0.0053 0.0117 0.0263
Brugia malayi hypothetical protein 0.0044 0.0092 0.03
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0087 0.0287
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0159 0.0364
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0067 0.0217
Toxoplasma gondii histone kinase SNF1, putative 0.0049 0.0105 0.015
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0192 0.0272
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0113 0.0159
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1141 0.3396 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0081 0.0202 0.0538
Trypanosoma brucei protein kinase, putative 0.0051 0.0113 0.0373
Echinococcus granulosus roundabout 2 0.0023 0.0026 0.0056
Entamoeba histolytica serine/threonine protein kinase, putative 0.0022 0.0024 0.0034
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0027 0.0087
Brugia malayi 6-phosphofructokinase 0.0114 0.0301 0.0994
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0074 0.0102
Loa Loa (eye worm) patched family protein 0.0019 0.0015 0.0045
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0074 0.024
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0052 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0356 0.1405
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0119 0.0317 0.0879
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0026 0.0024
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0087 0.0197
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0021
Echinococcus multilocularis conserved hypothetical protein 0.0015 0.0003 0.0001
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0047 0.0099 0.0222
Giardia lamblia Histone deacetylase 0.0842 0.2493 1
Echinococcus granulosus Immunoglobulin 0.0036 0.0067 0.015
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0051 0.0603
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Brugia malayi hypothetical protein 0.013 0.0351 0.1161
Echinococcus multilocularis hemicentin 1 0.0023 0.0026 0.0024
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0178 0.0588
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0021 0.0056
Loa Loa (eye worm) hypothetical protein 0.0043 0.0087 0.0287
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0192 0.0635
Loa Loa (eye worm) hypothetical protein 0.0078 0.0192 0.0635
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Leishmania major histone deacetylase, putative 0.0842 0.2493 0.8286
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0184 0.0513 0.2035
Mycobacterium ulcerans monoamine oxidase 0.0043 0.0089 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0078 0.0179
Schistosoma mansoni titin 0.0016 0.0008 0.0018
Loa Loa (eye worm) carboxylesterase 0.0081 0.0202 0.0669
Echinococcus granulosus carboxylesterase 5A 0.0479 0.1401 0.3211
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0025 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0033 0.0031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0051 0.0112
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0087 0.0284
Leishmania major hypothetical protein, conserved 0.0019 0.0016 0.0049
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0026 0.0024
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Mycobacterium ulcerans dehydrogenase 0.0043 0.0089 0.0098
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0108 0.0408
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0078 0.0174
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0049 0.0105 0.0346
Echinococcus multilocularis neuroglian 0.0048 0.0104 0.0102
Schistosoma mansoni hypothetical protein 0.0127 0.0342 0.0783
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0053 0.0186
Schistosoma mansoni amine oxidase 0.0043 0.0089 0.0204
Loa Loa (eye worm) patched family protein 0.0019 0.0015 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0023 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0162 0.0445 0.1478
Schistosoma mansoni chloride channel protein 0.0021 0.0021 0.0047
Onchocerca volvulus Protein patched homolog 0.0019 0.0015 0.0087
Brugia malayi Carboxylesterase family protein 0.0081 0.0202 0.0666
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0113 0.0255
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0051 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0051 0.0163
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0051 0.0049
Mycobacterium ulcerans oxidoreductase 0.0043 0.0089 0.0098
Brugia malayi Carboxylesterase family protein 0.0479 0.1401 0.4655
Loa Loa (eye worm) apoptosis regulator protein 0.0087 0.0219 0.0725
Loa Loa (eye worm) chloride channel 3 0.0021 0.0021 0.0066
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0021 0.0021 0.0019
Leishmania major hypothetical protein, conserved 0.0018 0.0011 0.0035
Brugia malayi glutathione reductase 0.004 0.0078 0.0254
Echinococcus granulosus histone deacetylase 6 0.1013 0.3008 0.6898
Plasmodium vivax casein kinase II beta chain, putative 0.0039 0.0075 0.0104
Schistosoma mansoni histone deacetylase 1 2 3 0.0422 0.1228 0.2817
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0201
Loa Loa (eye worm) patched family protein 0.0019 0.0015 0.0045
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Onchocerca volvulus 0.0053 0.0118 0.0806
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0292
Mycobacterium tuberculosis Possible oxidoreductase 0.0043 0.0089 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0011 0.0035
Plasmodium vivax importin-beta 2, putative 0.0031 0.0052 0.007
Onchocerca volvulus 0.0043 0.0087 0.0591
Loa Loa (eye worm) glutaminase 0.0561 0.1647 0.5473
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0051 0.0166
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0106 0.0278 0.0921
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0041 0.0082 0.1221
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0105 0.0241
Schistosoma mansoni cpg binding protein 0.0093 0.024 0.055
Mycobacterium ulcerans acyl-CoA synthetase 0.0146 0.0398 0.0546
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0051 0.0112
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0023 0.0026 0.0024
Echinococcus granulosus geminin 0.0513 0.1503 0.3444
Echinococcus multilocularis Immunoglobulin 0.0036 0.0067 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0269 0.0891
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.004 0.0128
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0051 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Plasmodium falciparum histone deacetylase 2 0.1013 0.3008 0.4339
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0119 0.0317 0.0879
Brugia malayi Latrophilin receptor protein 2 0.0098 0.0254 0.0837
Loa Loa (eye worm) transcription factor SMAD2 0.0363 0.105 0.3489
Mycobacterium ulcerans acetyl-CoA synthetase 0.0043 0.0087 0.0096
Echinococcus multilocularis aurora kinase A 0.017 0.0471 0.0469
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0051 0.0117
Loa Loa (eye worm) hypothetical protein 0.031 0.0891 0.296
Trichomonas vaginalis spcc417.12 protein, putative 0.0081 0.0202 0.0786
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0187 0.0521 0.0725
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0041 0.0139
Loa Loa (eye worm) hypothetical protein 0.0109 0.0287 0.095
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0087 0.0219 0.0217
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0007 0.0012
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0021 0.0066
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.023 0.0651 0.0649
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0021 0.0066
Schistosoma mansoni tar DNA-binding protein 0.0251 0.0715 0.164
Entamoeba histolytica protein kinase, putative 0.0192 0.0538 0.2108
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.024 0.0682 0.1565
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0051 0.0166
Trypanosoma cruzi histone deacetylase, putative 0.1013 0.3008 1
Echinococcus multilocularis twitchin 0.0016 0.0008 0.0006
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.0232 0.0625
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0051 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0094 0.0243 0.0804
Loa Loa (eye worm) hypothetical protein 0.0081 0.0202 0.0669
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Echinococcus multilocularis serine:threonine protein kinase Nek1 0.0017 0.0011 0.0009
Brugia malayi hypothetical protein 0.0019 0.0015 0.0042
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0016 0.0049
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0075 0.0509
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0078 0.0256
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0021 0.0022 0.0046
Echinococcus multilocularis smad 0.0025 0.0033 0.0031
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.013 0.035 0.0798
Plasmodium vivax replication factor C subunit 1, putative 0.0041 0.0082 0.0114
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0021 0.0066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0008 0.0018
Brugia malayi ecdysteroid receptor 0.0031 0.0051 0.0163
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0026 0.0085
Loa Loa (eye worm) histone deacetylase 7A 0.1013 0.3008 1
Brugia malayi Importin beta-1 subunit 0.0031 0.0052 0.0166
Echinococcus granulosus serine:threonine protein kinase 12 B 0.017 0.0471 0.1075
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0051 0.0166
Trichomonas vaginalis STE family protein kinase 0.0022 0.0024 0.0069
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Schistosoma mansoni DNA helicase recq5 0.0021 0.0021 0.0048
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0021 0.0047
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.013 0.035 0.1161
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0053 0.0186
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0113 0.0393
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0472 0.1871
Schistosoma mansoni acetyl-CoA synthetase 0.0043 0.0087 0.02
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0269
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0201
Plasmodium vivax acyl-CoA synthetase, putative 0.0109 0.0287 0.0409
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Onchocerca volvulus 0.0016 0.0008 0.0041
Echinococcus multilocularis dual specificity 0.0192 0.0538 0.0536
Trypanosoma cruzi cdc2-related kinase 1 0.005 0.0108 0.0357
Echinococcus multilocularis dnaJ subfamily B 0.1259 0.375 0.3749
Trypanosoma brucei DNA polymerase IV, putative 0.0171 0.0472 0.1567
Trichomonas vaginalis histone deacetylase, putative 0.0842 0.2493 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0002 0.0004
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0051 0.0049
Schistosoma mansoni titin 0.0023 0.0026 0.0061
Echinococcus granulosus histone deacetylase 3 0.0842 0.2493 0.5715
Entamoeba histolytica hypothetical protein 0.0192 0.0538 0.2108
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.03 0.0996
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0021 0.0022 0.0027
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0251 0.0715 0.2375
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0113 0.0373
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0081 0.0202 0.02
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0008 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0087 0.0284
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0087 0.0219 0.0498
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0021 0.0025
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0113 0.0427
Schistosoma mansoni smad 0.0025 0.0033 0.0075
Echinococcus granulosus thyrotropin releasing hormone receptor 0.024 0.0682 0.1561
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0081 0.0202 0.0464
Onchocerca volvulus 0.0043 0.0089 0.0601
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0471 0.1079
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.024 0.0682 0.0681
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0089 0.0199
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0062 0.0146 0.0482
Brugia malayi DKFZp564C0469 protein 0.0041 0.0082 0.0266
Onchocerca volvulus 0.0081 0.0202 0.1387
Schistosoma mansoni histone deacetylase 4 5 0.1013 0.3008 0.6899
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0043 0.0087 0.0197
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0028 0.0026
Schistosoma mansoni topbp1 0.0041 0.0082 0.0188
Loa Loa (eye worm) MH2 domain-containing protein 0.0363 0.105 0.3489
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Onchocerca volvulus 0.0477 0.1395 0.965
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0058 0.0133
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0025 0.0081
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0078 0.0256
Mycobacterium ulcerans hypothetical protein 0.0146 0.0398 0.0546
Loa Loa (eye worm) hypothetical protein 0.013 0.0351 0.1164
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0248
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0002 0.0005
Trypanosoma brucei DNA polymerase eta, putative 0.0157 0.043 0.1427
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0082 0.0302
Trypanosoma cruzi histone deacetylase, putative 0.1013 0.3008 1
Loa Loa (eye worm) hypothetical protein 0.0842 0.2493 0.8286
Onchocerca volvulus 0.0018 0.0011 0.0065
Echinococcus multilocularis 0.0043 0.0089 0.0087
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0021 0.0019
Trichomonas vaginalis histone deacetylase, putative 0.0842 0.2493 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0025 0.0074
Schistosoma mansoni BC026374 protein (S09 family) 0.0081 0.0202 0.0464
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0021 0.0021 0.0066
Echinococcus multilocularis cpg binding protein 0.0093 0.024 0.0238
Leishmania major hypothetical protein, conserved 0.0021 0.0021 0.0066
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.006 0.0139 0.0137
Echinococcus granulosus titin 0.0016 0.0008 0.0014
Toxoplasma gondii CBS family protein 0.0021 0.0021 0.0029
Echinococcus granulosus dnaJ subfamily B 0.1259 0.375 0.86
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.026 0.0741 0.2459
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0021 0.0021 0.0056
Loa Loa (eye worm) proteasome 26S subunit 0.0016 0.0007 0.0019
Onchocerca volvulus 0.0019 0.0015 0.0087
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.03 0.3623
Brugia malayi Pre-SET motif family protein 0.0033 0.0058 0.0187
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0008 0.0018
Loa Loa (eye worm) histone deacetylase 11 0.0422 0.1228 0.4081
Plasmodium falciparum replication factor C subunit 1, putative 0.0041 0.0082 0.0114
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0021 0.0021 0.0066
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0022 0.0024 0.0077
Brugia malayi histone deacetylase 3 (HD3) 0.0842 0.2493 0.8286
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0084 0.057
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0108 0.0248
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0007 0.0017
Schistosoma mansoni septate junction protein 0.0023 0.0026 0.0061
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0105 0.0274 0.0906
Brugia malayi Heterochromatin protein 1 0.0069 0.0167 0.055
Plasmodium falciparum histone deacetylase 1 0.0842 0.2493 0.3595
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0101 0.0262 0.0716
Brugia malayi MH2 domain containing protein 0.0363 0.105 0.3487
Schistosoma mansoni glutaminase 0.0561 0.1647 0.3777
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0024 0.0069
Brugia malayi hypothetical protein 0.0043 0.0089 0.0289
Echinococcus granulosus histone deacetylase 1 0.0842 0.2493 0.5715
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.002
Brugia malayi Histone deacetylase family protein 0.1013 0.3008 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0051 0.0117
Onchocerca volvulus Protein patched homolog 0.0019 0.0015 0.0087
Toxoplasma gondii histone deacetylase HDAC5 0.0422 0.1228 0.1772
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0027 0.0087
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.0232 0.0625
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.002 0.0055
Loa Loa (eye worm) carboxylesterase 0.0081 0.0202 0.0669
Echinococcus multilocularis para nitrobenzyl esterase 0.0081 0.0202 0.02
Loa Loa (eye worm) AUR protein kinase 0.017 0.0471 0.1561
Leishmania major hypothetical protein, conserved 0.0016 0.0008 0.0023
Toxoplasma gondii NEK kinase 0.0022 0.0024 0.0033
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0021 0.0022 0.0027
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.03 0.115
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0051 0.0177
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0066
Echinococcus granulosus neuroligin 0.0081 0.0202 0.0459
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0164
Loa Loa (eye worm) hypothetical protein 0.0241 0.0684 0.227
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0058 0.0133
Schistosoma mansoni flap endonuclease-1 0.005 0.0109 0.025
Loa Loa (eye worm) histone deacetylase 3 0.0842 0.2493 0.8286
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0008 0.0018
Entamoeba histolytica histone deacetylase, putative 0.0842 0.2493 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0041 0.0082 0.0302
Brugia malayi Pax transcription activation domain interacting protein 0.0041 0.0082 0.0266
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0026 0.0085
Brugia malayi Carboxylesterase family protein 0.0479 0.1401 0.4655
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0113 0.0259
Brugia malayi hypothetical protein 0.0158 0.0434 0.1437
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0081 0.0202 0.0786
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0414 0.0412
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0108 0.0408
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0027 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0094 0.0243 0.0804
Onchocerca volvulus 0.0043 0.0087 0.0591
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0039 0.0075 0.0247
Schistosoma mansoni hypothetical protein 0.0212 0.0596 0.1367
Brugia malayi hypothetical protein 0.0078 0.0192 0.0632
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0675 0.1548
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.002
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0002 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0025 0.0078
Leishmania major CBS domain protein, conserved 0.0021 0.0021 0.0066
Echinococcus granulosus Smad4 0.0025 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Onchocerca volvulus 0.0249 0.0709 0.4902
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0051 0.0163
Trichomonas vaginalis AGC family protein kinase 0.017 0.0471 0.1865
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.023 0.0651 0.259
Trypanosoma brucei NIMA-related protein kinase 0.0022 0.0024 0.0077
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0187 0.0521 1
Loa Loa (eye worm) hypothetical protein 0.0109 0.0287 0.095
Loa Loa (eye worm) AUR protein kinase 0.017 0.0471 0.1561
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0074 0.0885
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0055 0.0125 0.0413
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0049 0.0105 0.0346
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0051 0.0112
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0041 0.0082 0.0269
Schistosoma mansoni casein kinase II beta subunit 0.0039 0.0075 0.0173
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0021 0.0066
Leishmania major hypothetical protein, unknown function 0.0015 0.0003 0.0007
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0049 0.0105 0.0346
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0022 0.0025 0.0035
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0027 0.0087
Entamoeba histolytica hypothetical protein 0.0036 0.0065 0.0201
Schistosoma mansoni protein kinase subunit beta 0.0014 0.0001 0.0002
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0021 0.0056
Onchocerca volvulus 0.0015 0.0003 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0082 0.0302
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Brugia malayi Carboxylesterase family protein 0.0081 0.0202 0.0666
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0383 0.0524
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0019 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0168
Schistosoma mansoni protein kinase subunit beta 0.006 0.0139 0.0318
Plasmodium falciparum DNA repair protein REV1, putative 0.004 0.008 0.0111
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0021 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0066
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0043 0.0087 0.0287
Toxoplasma gondii ImpB/MucB/SamB family protein 0.004 0.008 0.0114
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0051 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0105 0.0241
Brugia malayi SWIRM domain containing protein 0.0043 0.0089 0.0289
Treponema pallidum DNA ligase (lig) 0.0041 0.0082 0.0979
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.005 0.0108 0.0357
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0021 0.0021 0.0019
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0052 0.0073
Schistosoma mansoni smad1 5 8 and 0.0025 0.0033 0.0075
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0021 0.0019
Toxoplasma gondii chorismate synthase, putative 0.2314 0.6929 1
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.017 0.047 0.0468
Brugia malayi topoisomerase 0.0041 0.0082 0.0266
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0021 0.0021 0.0019
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0312 0.0899 0.2062
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.03 0.0689
Entamoeba histolytica cell division protein kinase 2, putative 0.005 0.0108 0.0374
Brugia malayi RE40412p 0.0015 0.0003 0.0004
Echinococcus multilocularis acetylcholinesterase 0.0479 0.1401 0.14
Echinococcus multilocularis histone deacetylase 6 0.1013 0.3008 0.3007
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0041 0.0082 0.0302
Mycobacterium ulcerans hypothetical protein 0.004 0.008 0.0086
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0113 0.0111
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0383 0.1271
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0146 0.0398 0.1117
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.03 0.115
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0024 0.0069
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0043 0.0087 0.0197
Giardia lamblia DINP protein human, muc B family 0.0143 0.039 0.1543
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0051 0.0163
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0051 0.0049
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0306 0.0879 0.2916
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.026 0.0741 0.2461
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0074 0.0243
Brugia malayi Flap endonuclease-1 0.0055 0.0125 0.041
Mycobacterium ulcerans acyl-CoA synthetase 0.0146 0.0398 0.0546
Trypanosoma cruzi cdc2-related kinase 3 0.005 0.0108 0.0357
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.05 0.1982
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.0025 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0053 0.0186
Echinococcus multilocularis BRCA1 associated protein 0.0019 0.0016 0.0014
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0049 0.0105 0.0147
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0008 0.0018
Leishmania major chloride channel protein, putative 0.0021 0.0021 0.0066
Schistosoma mansoni alkaline phosphatase 0.017 0.047 0.1078
Echinococcus granulosus chromobox protein 1 0.0069 0.0167 0.0379
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0008 0.0023
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0159 0.0364
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.0827 0.3277
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0063 0.014
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0016 0.0008 0.0023
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0008 0.002
Brugia malayi protein unc-22 0.0016 0.0008 0.002
Brugia malayi Protein kinase domain containing protein 0.0192 0.0538 0.1783
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0082 0.0269
Loa Loa (eye worm) hypothetical protein 0.0188 0.0525 0.1742
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.008 0.0078
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0187 0.0521 0.0725
Schistosoma mansoni ets-related 0.0221 0.0625 0.1433
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0051 0.0044
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0065 0.0145
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0092 0.0129
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Schistosoma mansoni septate junction protein 0.0023 0.0026 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0051 0.0177
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0041 0.0082 0.0268
Loa Loa (eye worm) acetyltransferase 0.0151 0.0414 0.1375
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0051 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0082 0.0269
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0108 0.0106
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0039 0.0075 0.0241
Entamoeba histolytica protein kinase domain containing protein 0.0192 0.0538 0.2108
Echinococcus granulosus cpg binding protein 0.0093 0.024 0.0546
Loa Loa (eye worm) acetylcholinesterase 1 0.0479 0.1401 0.4656
Entamoeba histolytica acyl-coA synthetase, putative 0.0146 0.0398 0.1542
Loa Loa (eye worm) patched family protein 0.0019 0.0015 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0074 0.0243
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0741 0.2954
Onchocerca volvulus 0.0051 0.0113 0.0769
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0269
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Brugia malayi chromobox protein homolog 3 0.0039 0.0075 0.0245
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0074 0.0102
Echinococcus granulosus tumor protein p63 0.0363 0.1051 0.2406
Schistosoma mansoni hypothetical protein 0.0087 0.0219 0.0502
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0022 0.0025 0.0081
Loa Loa (eye worm) AUR protein kinase 0.017 0.0471 0.1561
Entamoeba histolytica protein kinase, putative 0.017 0.0471 0.1836
Toxoplasma gondii exonuclease III APE 0.0038 0.0074 0.0106
Echinococcus multilocularis Immunoglobulin 0.0036 0.0067 0.0065
Toxoplasma gondii NEK kinase 0.0022 0.0024 0.0033
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0113 0.0111
Schistosoma mansoni patched 1 0.0132 0.0356 0.0816
Brugia malayi cell division control protein 2 homolog 0.005 0.0108 0.0354
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0043 0.0089 0.0124
Giardia lamblia Replication factor C, subunit 1 0.0041 0.0082 0.0302
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0087 0.0287
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0025 0.0053
Onchocerca volvulus 0.0019 0.0015 0.0087
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0143 0.0329
Trypanosoma brucei aurora B kinase 0.017 0.0471 0.1561
Brugia malayi intracellular kinase 0.0051 0.0113 0.037
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0087 0.0219 0.0217
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0058 0.0056
Schistosoma mansoni cell adhesion molecule 0.0047 0.0099 0.0226
Schistosoma mansoni importin beta-1 0.0031 0.0052 0.0118
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0119 0.0317 0.0879
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0021 0.0021 0.0043
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0055 0.0125 0.0413
Loa Loa (eye worm) hypothetical protein 0.0132 0.0356 0.118
Plasmodium falciparum NIMA related kinase 4 0.0022 0.0024 0.003
Entamoeba histolytica acyl-CoA synthetase, putative 0.0146 0.0398 0.1542
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0192 0.0538 0.1785
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0008 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0021 0.0066
Loa Loa (eye worm) hypothetical protein 0.0109 0.0287 0.095
Plasmodium falciparum flap endonuclease 1 0.0055 0.0125 0.0176
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0016 0.0049
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0043 0.0089 0.0204
Toxoplasma gondii histone lysine-specific demethylase 0.0043 0.0089 0.0127
Echinococcus multilocularis neuroglian 0.0023 0.0026 0.0024
Leishmania major histone deacetylase, putative 0.0842 0.2493 0.8286
Brugia malayi ImpB/MucB/SamB family protein 0.013 0.035 0.1158
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Plasmodium falciparum NIMA related kinase 2 0.0022 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0078 0.0286
Schistosoma mansoni hypothetical protein 0.0035 0.0063 0.0145
Loa Loa (eye worm) hypothetical protein 0.0272 0.0778 0.2585
Brugia malayi Immunoglobulin I-set domain containing protein 0.0528 0.1549 0.5146
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0052 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0051 0.0163
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0238 0.0675 0.1544
Echinococcus granulosus H:Cl exchange transporter 4 0.0021 0.0021 0.0043
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.0011 0.0012
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Schistosoma mansoni cell adhesion molecule 0.0023 0.0026 0.0061
Giardia lamblia Hypothetical protein 0.0022 0.0025 0.0074
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0043 0.0089 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0113 0.0427
Trichomonas vaginalis glutaminase, putative 0.0561 0.1647 0.6597
Schistosoma mansoni chromobox protein 0.0069 0.0167 0.0383
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0098 0.0254 0.0837
Loa Loa (eye worm) hypothetical protein 0.0081 0.0202 0.0669
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0021 0.0021
Brugia malayi Fibronectin type III domain containing protein 0.0036 0.0067 0.0217
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.03 0.0996
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0074 0.0243
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0192 0.0272
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0021 0.0021 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0383 0.0879
Trypanosoma cruzi histone deacetylase, putative 0.0422 0.1228 0.4081
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0078 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0108 0.0248
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0383 0.0875
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.005 0.0108 0.0357
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0002 0.0005
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0007 0.0005
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0092 0.0345
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0098 0.0254 0.0252
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0051 0.0117
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0008 0.0023
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0033 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0051 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0081 0.03
Onchocerca volvulus 0.0081 0.0202 0.1387
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0049 0.0105 0.0346
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0078 0.0108
Brugia malayi nuclear receptor NHR-88 0.0014 0.0002 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0078 0.0256
Schistosoma mansoni amine oxidase 0.0043 0.0089 0.0204
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0058 0.0129
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0098 0.0254 0.0577
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0043 0.0089 0.0124
Onchocerca volvulus 0.0041 0.0082 0.0553
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0167 0.0645
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0065 0.015
Schistosoma mansoni cpg binding protein 0.0093 0.024 0.055
Brugia malayi serine/threonine protein kinase 6 0.017 0.0471 0.1559
Treponema pallidum fructose-bisphosphate aldolase 0.0289 0.0827 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0842 0.2493 1
Brugia malayi hypothetical protein 0.005 0.0109 0.0357
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0027 0.0084
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0087 0.0219 0.0502
Loa Loa (eye worm) hypothetical protein 0.0129 0.0348 0.1154
Schistosoma mansoni ran 0.0023 0.0027 0.0062
Trichomonas vaginalis histone deacetylase, putative 0.0842 0.2493 1
Brugia malayi RNA, U transporter 1 0.0088 0.0223 0.0737
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0025 0.0081
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0074 0.0243
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0041 0.0082 0.0302
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0049 0.0107
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0008 0.0013
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0021 0.0056
Loa Loa (eye worm) phosphofructokinase 0.0114 0.03 0.0996
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0043 0.0087 0.0096
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0025 0.0053
Schistosoma mansoni gliotactin 0.0081 0.0202 0.0464
Trypanosoma brucei trypanothione reductase 0.004 0.0078 0.0257
Plasmodium vivax flap endonuclease 1, putative 0.0055 0.0125 0.0176
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.005 0.0108 0.0155
Plasmodium falciparum lipid/sterol:H+ symporter 0.0019 0.0015 0.0016
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0021 0.0029
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0002 0.0001
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.002
Plasmodium vivax casein kinase II beta chain, putative 0.0039 0.0075 0.0104
Toxoplasma gondii IMP dehydrogenas 0.0021 0.0021 0.0029
Schistosoma mansoni DNA helicase recq1 0.0021 0.0021 0.0048
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0074 0.0271
Schistosoma mansoni cell adhesion molecule 0.0023 0.0026 0.0061
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0021 0.0066
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0022 0.0024 0.0077
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Mycobacterium ulcerans glutaminase 0.0561 0.1647 0.2354
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Plasmodium vivax histone deacetylase, putative 0.0422 0.1228 0.1769
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0105 0.0241
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0049 0.0105 0.015
Echinococcus multilocularis protein dispatched 1 0.0151 0.0412 0.041
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.022
Schistosoma mansoni hypothetical protein 0.0513 0.1503 0.3447
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Brugia malayi MH1 domain containing protein 0.0025 0.0033 0.0103
Brugia malayi hypothetical protein 0.0016 0.0007 0.0018
Loa Loa (eye worm) RecQ helicase 0.0021 0.0021 0.0066
Brugia malayi Fli-1 protein 0.0221 0.0625 0.2072
Brugia malayi hypothetical protein 0.0014 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0292
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0109 0.0287 0.0385
Trypanosoma cruzi DNA polymerase eta, putative 0.0067 0.016 0.0529
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0113 0.0393
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.013 0.035 0.0348
Brugia malayi Patched related family protein 12 0.0019 0.0015 0.0042
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0308 0.0885 0.3509
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0025 0.0074
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0827 0.33
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0078 0.0286
Echinococcus granulosus AMPK beta subunit 0.0112 0.0295 0.0671
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0119 0.0317 0.0429
Loa Loa (eye worm) latrophilin receptor protein 2 0.0098 0.0254 0.084
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0269
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0074 0.0158
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0051 0.0069
Loa Loa (eye worm) glutaminase 2 0.0561 0.1647 0.5473
Chlamydia trachomatis DNA ligase 0.0041 0.0082 0.0089
Schistosoma mansoni vesicular amine transporter 0.0036 0.0067 0.0154
Schistosoma mansoni hypothetical protein 0.0087 0.0219 0.0502
Toxoplasma gondii thioredoxin reductase 0.004 0.0078 0.0112
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Schistosoma mansoni protein kinase subunit beta 0.0112 0.0295 0.0676
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Leishmania major 4-coumarate:coa ligase-like protein 0.0146 0.0398 0.1319
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0075 0.0276
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0087 0.0219 0.0498
Trypanosoma cruzi histone deacetylase 1, putative 0.0842 0.2493 0.8286
Loa Loa (eye worm) hypothetical protein 0.0158 0.0434 0.1439
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0146 0.0398 0.0546
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Onchocerca volvulus 0.0015 0.0003 0.0008
Loa Loa (eye worm) glutathione reductase 0.004 0.0078 0.0257
Schistosoma mansoni tar DNA-binding protein 0.0251 0.0715 0.164
Brugia malayi nuclear receptor RXR 0.0014 0.0002 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0098 0.0254 0.0577
Schistosoma mansoni smad1 5 8 and 0.0025 0.0033 0.0075
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0043 0.0087 0.0284
Echinococcus granulosus conserved hypothetical protein 0.0015 0.0003 0.0003
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0078 0.0174
Onchocerca volvulus 0.0105 0.0274 0.1886
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0036 0.0067 0.0154
Leishmania major protein kinase, putative 0.017 0.0471 0.1561
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0113 0.0373
Echinococcus multilocularis microtubule associated protein 2 0.1462 0.4361 0.4359
Loa Loa (eye worm) hypothetical protein 0.0146 0.0398 0.1319
Brugia malayi CHE-14 protein 0.0132 0.0356 0.1178
Echinococcus multilocularis expressed conserved protein 0.0289 0.0829 0.0827
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0084 0.0312
Giardia lamblia DNA damage repair protein 0.004 0.008 0.0294
Echinococcus granulosus alkaline phosphatase 0.017 0.047 0.1074
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0306 0.088 0.2547
Mycobacterium tuberculosis Conserved hypothetical protein 0.013 0.035 0.0976
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0842 0.2493 1
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0238 0.0675 0.2241
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0002 0.0001
Mycobacterium ulcerans carboxylesterase, LipT 0.0081 0.0202 0.0263
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0111 0.0294 0.0674
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0078 0.0256
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0112 0.0295 0.0976
Trypanosoma cruzi DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0143 0.0324
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0109 0.0287 0.0385
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0026 0.0085
Entamoeba histolytica protein kinase domain containing protein 0.017 0.0471 0.1836
Trypanosoma brucei cdc2-related kinase 1 0.005 0.0108 0.0357
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0041 0.0082 0.0089
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0472 0.1871
Trichomonas vaginalis DNA polymerase eta, putative 0.0184 0.0513 0.2035
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.1181
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0043 0.0087 0.0197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0051 0.0166
Brugia malayi CHD4 protein 0.0016 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0023
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0051 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0051 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0033 0.0106
Loa Loa (eye worm) histone deacetylase 0.1013 0.3008 1
Schistosoma mansoni chloride channel protein 0.0021 0.0021 0.0047
Brugia malayi AMP-binding enzyme family protein 0.0146 0.0398 0.1316
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0008 0.0018
Schistosoma mansoni hypothetical protein 0.0015 0.0003 0.0007
Brugia malayi hypothetical protein 0.0019 0.0015 0.0042
Echinococcus granulosus BC026374 protein S09 family 0.0081 0.0202 0.0459
Echinococcus granulosus protein kinase shaggy 0.0051 0.0113 0.0255
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0023 0.0026 0.0061
Entamoeba histolytica protein kinase, putative 0.017 0.0471 0.1836
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Echinococcus granulosus cyclin dependent kinase 0.005 0.0108 0.0244
Trypanosoma brucei hypothetical protein, conserved 0.004 0.008 0.0263
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0043 0.0087 0.0197
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Giardia lamblia Casein kinase II beta chain 0.0039 0.0075 0.0276
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0043 0.0087 0.0287
Trypanosoma cruzi DNA damage repair protein, putative 0.004 0.008 0.0263
Trypanosoma cruzi DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0016 0.0007 0.0019
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0051 0.0339
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0041 0.0082 0.0266
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0021 0.0029
Loa Loa (eye worm) hypothetical protein 0.0044 0.0092 0.0302
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0146 0.0398 0.1117
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0087 0.0197
Plasmodium falciparum acyl-CoA synthetase 0.0109 0.0287 0.0409
Echinococcus multilocularis tumor protein p63 0.0363 0.1051 0.1049
Entamoeba histolytica hypothetical protein 0.0025 0.0034 0.0074
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0041 0.0082 0.0302
Schistosoma mansoni nuclear receptor 0.0014 0.0002 0.0005
Onchocerca volvulus 0.0146 0.0398 0.2741
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0021 0.0066
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0325
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0103 0.0269 0.0735
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0741 0.2954
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0082 0.0302
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0074 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0192 0.0635
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0021 0.0063
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0023 0.0048
Mycobacterium ulcerans chorismate synthase 0.2314 0.6929 1
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0016 0.0007 0.0011
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0021 0.0047
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0167 0.0553
Echinococcus multilocularis muscleblind protein 0.0919 0.2726 0.2724
Echinococcus multilocularis neuroligin 0.0081 0.0202 0.02
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0143 0.039 0.1095
Schistosoma mansoni nephrin 0.0048 0.0104 0.0238
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0113 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0092 0.0212
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0044 0.0144
Loa Loa (eye worm) oxidoreductase 0.0043 0.0087 0.0287
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0022 0.0024 0.003
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0293 0.0841 0.2793
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.005 0.0108 0.0357
Loa Loa (eye worm) hypothetical protein 0.0081 0.0202 0.0669
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0021 0.0021 0.0043
Echinococcus multilocularis hemicentin 1 0.0023 0.0026 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0741 0.2954
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0022 0.0025 0.0058
Trypanosoma brucei DNA polymerase IV, putative 0.0184 0.0513 0.1702
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0414 0.1372
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.03 0.0298
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0112 0.0295 0.1158
Chlamydia trachomatis dehyroquinate synthase 0.0119 0.0317 0.0429
Brugia malayi ecdysone receptor 0.0014 0.0002 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0146 0.0398 0.0546
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Toxoplasma gondii NEK kinase 0.0022 0.0024 0.0033
Plasmodium vivax patched family protein, putative 0.0019 0.0015 0.0016
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0052 0.0168
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0402 0.0917
Brugia malayi nuclear hormone receptor 0.0031 0.0051 0.0163
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0043 0.0087 0.0197
Echinococcus multilocularis carboxylesterase 5A 0.0479 0.1401 0.14
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0103 0.0269 0.0735
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0092 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Mycobacterium ulcerans DNA polymerase IV 0.0184 0.0513 0.0712
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0035
Onchocerca volvulus 0.0437 0.1275 0.8823
Trypanosoma brucei DNA damage repair protein, putative 0.004 0.008 0.0263
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Trichomonas vaginalis brca1-associated protein, putative 0.0019 0.0016 0.0035
Chlamydia trachomatis chorismate synthase 0.2314 0.6929 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0034 0.011
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0008 0.0023
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0008 0.001
Leishmania major acetyl-CoA synthetase, putative 0.0043 0.0087 0.0287
Schistosoma mansoni hypothetical protein 0.0088 0.0224 0.0514
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0087 0.0287
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0027 0.0057
Trichomonas vaginalis AGC family protein kinase 0.017 0.0471 0.1865
Giardia lamblia Aurora kinase 0.017 0.0471 0.1865
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0113 0.0427
Brugia malayi TAR-binding protein 0.0251 0.0715 0.2373
Mycobacterium tuberculosis Probable reductase 0.0091 0.0232 0.0625
Leishmania major DNA damage repair protein, putative 0.004 0.008 0.0263
Schistosoma mansoni hypothetical protein 0.0098 0.0254 0.0581
Entamoeba histolytica Ran family GTPase 0.0023 0.0027 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0146 0.0398 0.1316
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Schistosoma mansoni hypothetical protein 0.0261 0.0746 0.1711
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0021 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0087 0.0096
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0143 0.0141
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0008 0.0018
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0293 0.0841 0.2793
Loa Loa (eye worm) hypothetical protein 0.0437 0.1275 0.4237
Echinococcus multilocularis histone deacetylase 0.1013 0.3008 0.3007
Leishmania major trypanothione reductase 0.004 0.0078 0.0257
Loa Loa (eye worm) hypothetical protein 0.0422 0.1228 0.4081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0238 0.0675 0.0673
Brugia malayi Protein kinase domain containing protein 0.005 0.0108 0.0354
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0074 0.0165
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0021
Plasmodium vivax acetyl-CoA synthetase, putative 0.0043 0.0087 0.0122
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0043 0.0087 0.0287
Entamoeba histolytica hypothetical protein 0.0041 0.0082 0.0268
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.022
Plasmodium vivax SET domain protein, putative 0.0033 0.0058 0.0079
Trypanosoma cruzi GMP reductase 0.0021 0.0021 0.0066
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.0827 0.3277
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0479 0.1401 0.3214
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0009 0.0024
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0112 0.0295 0.0976
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0002 0.0004
Brugia malayi RNA binding protein 0.0251 0.0715 0.2373
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0112 0.0295 0.0976
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0051 0.0117
Schistosoma mansoni hypothetical protein 0.0098 0.0254 0.0581
Plasmodium falciparum serine/threonine protein kinase KIN 0.0049 0.0105 0.0147
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0021 0.0066
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0089 0.0124
Loa Loa (eye worm) hypothetical protein 0.0105 0.0274 0.0909
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0043 0.0087 0.0085
Mycobacterium ulcerans DNA polymerase IV 0.0184 0.0513 0.0712
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0058 0.0083
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0051 0.0049
Toxoplasma gondii histone lysine methyltransferase SET1 0.0172 0.0477 0.0688
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0269 0.0891
Brugia malayi Pre-SET motif family protein 0.0219 0.0619 0.2053
Brugia malayi MH1 domain containing protein 0.0025 0.0033 0.0103
Echinococcus granulosus contactin 0.0023 0.0026 0.0056
Loa Loa (eye worm) hypothetical protein 0.0065 0.0153 0.0505
Echinococcus multilocularis roundabout 2 0.0023 0.0026 0.0024
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.017 0.047 0.1074
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0011 0.0021
Echinococcus granulosus flap endonuclease 1 0.0055 0.0125 0.0282
Schistosoma mansoni brca1-associated protein (brap2) 0.0019 0.0016 0.0036
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0192 0.0538 0.1785
Loa Loa (eye worm) Csnk2b protein 0.0039 0.0075 0.0247
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0472 0.1871
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0269
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0101 0.0262 0.0716
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0087 0.0284
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0043 0.0089 0.0124
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0067 0.016 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0105 0.0241
Schistosoma mansoni ran 0.0023 0.0027 0.0062
Leishmania major 4-coumarate:coa ligase-like protein 0.0146 0.0398 0.1319
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0178 0.0176
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0051 0.0072
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.0011 0.0009
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0087 0.0287
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.0009 0.0016
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0025 0.0078
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0008 0.0013
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0146 0.0398 0.0546
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0066
Brugia malayi Csnk2b protein 0.0039 0.0075 0.0245
Plasmodium falciparum casein kinase II beta chain 0.0039 0.0075 0.0104
Brugia malayi nuclear receptor NHR-88 0.0031 0.0051 0.0163
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.022
Plasmodium vivax chorismate synthase 0.2314 0.6929 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0039 0.0075 0.0247
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Loa Loa (eye worm) hypothetical protein 0.0308 0.0885 0.2939
Echinococcus multilocularis Smad4 0.0025 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0043 0.0087 0.0197
Onchocerca volvulus 0.0081 0.0202 0.1387
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.0232 0.0625
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0109 0.0287 0.0788
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0108 0.0408
Schistosoma mansoni tar DNA-binding protein 0.0251 0.0715 0.164
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0025 0.0074
Echinococcus multilocularis histone deacetylase 6 0.1032 0.3066 0.3064
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0008 0.001
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0008 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0192 0.0635
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0292
Entamoeba histolytica protein kinase, putative 0.0051 0.0113 0.0393
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0103 0.0269 0.0735
Trypanosoma cruzi FHA domain containing protein, putative 0.0041 0.0082 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0082 0.0302
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0074 0.0271
Echinococcus multilocularis protein patched 0.0132 0.0356 0.0354
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0043 0.0087 0.0287
Trypanosoma brucei hypothetical protein, conserved 0.004 0.008 0.0263
Schistosoma mansoni zinc finger protein 0.0014 0.0002 0.0005
Toxoplasma gondii hypothetical protein 0.01 0.0259 0.0373
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0078 0.0252
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0016 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.1181
Onchocerca volvulus 0.0081 0.0202 0.1387
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0039 0.0075 0.0107
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Plasmodium falciparum thioredoxin reductase 0.004 0.0078 0.0108
Trypanosoma cruzi protein kinase, putative 0.0017 0.0011 0.0033
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0087 0.0221 0.073
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0087 0.0284
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0081 0.0113
Brugia malayi loechrig isoform VII 0.023 0.0651 0.2158
Schistosoma mansoni protein kinase subunit gamma 0.023 0.0651 0.1492
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Schistosoma mansoni microtubule-associated protein tau 0.1462 0.4361 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0023 0.0026 0.0056
Loa Loa (eye worm) hypothetical protein 0.0081 0.0202 0.0669
Echinococcus granulosus Niemann Pick C1 protein 0.0308 0.0885 0.2025
Brugia malayi ImpB/MucB/SamB family protein 0.0157 0.043 0.1424
Toxoplasma gondii histone deacetylase HDAC3 0.0842 0.2493 0.3597
Trypanosoma brucei cdc2-related kinase 3 0.005 0.0108 0.0357
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0033 0.0071
Leishmania major acetyl-CoA synthetase, putative 0.0043 0.0087 0.0287
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0472 0.1871
Echinococcus granulosus serine:threonine kinase SAD 1 0.0049 0.0105 0.0236
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0261 0.0746 0.1711
Schistosoma mansoni nephrin 0.0023 0.0026 0.0061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0383 0.0381
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Entamoeba histolytica cell division protein kinase 2, putative 0.005 0.0108 0.0374
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0043 0.0087 0.0096
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0051 0.0117
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0025 0.0032
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0146 0.0398 0.1117
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0022 0.0024 0.0077
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.0232 0.0625
Echinococcus granulosus histone deacetylase 6 0.1032 0.3066 0.7029
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0619 0.1823 0.606
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0098 0.0254 0.0252
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0008 0.0006
Schistosoma mansoni roundabout 0.0023 0.0026 0.0061
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0043 0.0087 0.0096
Leishmania major DNA polymerase kappa, putative 0.004 0.008 0.0263
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0008 0.0013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0028 0.0064
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0019 0.0016 0.0049
Echinococcus granulosus Protein patched homolog 1 0.0132 0.0356 0.0812
Trypanosoma cruzi aurora B kinase, putative 0.017 0.0471 0.1561
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Schistosoma mansoni DNA polymerase eta 0.0157 0.043 0.0986
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0019 0.0016 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0008 0.0018
Brugia malayi N-terminal motif family protein 0.019 0.053 0.1758
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0027 0.0034
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.013 0.035 0.0803
Trypanosoma cruzi chloride channel protein, putative 0.0021 0.0021 0.0066
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0051 0.0339
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0007 0.0018
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0063 0.0061
Giardia lamblia Kinase, CAMK CAMKL 0.0049 0.0105 0.0395
Loa Loa (eye worm) hypothetical protein 0.0049 0.0105 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0189 0.0527 0.1208
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.03 0.0689
Echinococcus granulosus cyclin dependent kinase 1 0.005 0.0108 0.0244
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0051 0.0072
Toxoplasma gondii hypothetical protein 0.0019 0.0015 0.002
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Echinococcus granulosus dna polymerase kappa 0.0184 0.0513 0.1172
Leishmania major histone deacetylase, putative 0.1013 0.3008 1
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0024 0.0069
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0007 0.0017
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.017 0.0471 0.0469
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.017 0.047 0.0468
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0256
Brugia malayi Voltage gated chloride channel family protein 0.0021 0.0021 0.0063
Echinococcus multilocularis roundabout 2 0.0059 0.0135 0.0133
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0025 0.0074
Loa Loa (eye worm) hypothetical protein 0.0919 0.2726 0.9059
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0167 0.0645
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0528 0.1549 0.5147
Plasmodium vivax glutathione reductase, putative 0.004 0.0078 0.0108
Loa Loa (eye worm) hypothetical protein 0.0146 0.0398 0.1319
Brugia malayi Carboxylesterase family protein 0.0081 0.0202 0.0666
Echinococcus granulosus BRCA1 associated protein 0.0019 0.0016 0.0031
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0074 0.0236
Trypanosoma brucei SNF1-related protein kinases, putative 0.0049 0.0105 0.0346
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0033 0.0075
Loa Loa (eye worm) hypothetical protein 0.0081 0.0202 0.0669
Trichomonas vaginalis histone deacetylase, putative 0.0842 0.2493 1
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0069 0.0144
Onchocerca volvulus 0.0044 0.0092 0.0626
Plasmodium falciparum importin beta, putative 0.0031 0.0052 0.007
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Echinococcus granulosus hemicentin 1 0.0023 0.0026 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Echinococcus multilocularis histone deacetylase 6 0.1013 0.3008 0.3007
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0306 0.088 0.1269
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0051 0.0163
Trypanosoma cruzi cdc2-related kinase 3 0.005 0.0108 0.0357
Brugia malayi hypothetical protein 0.0036 0.0067 0.0217
Trypanosoma cruzi DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Schistosoma mansoni cpg binding protein 0.0088 0.0225 0.0515
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0025 0.0081
Trypanosoma cruzi NIMA-related kinase, putative 0.0022 0.0024 0.0077
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.031 0.0891 0.2958
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0007
Echinococcus multilocularis alkaline phosphatase 0.017 0.047 0.0468
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.023 0.0651 0.1488
Echinococcus multilocularis titin 0.0016 0.0008 0.0006
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0025 0.0032
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0025 0.0023
Brugia malayi hypothetical protein 0.0081 0.0202 0.0666
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0016 0.0007 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0082 0.0302
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0187 0.0521 0.6298
Schistosoma mansoni chromosome transmission fidelity factor 0.0041 0.0082 0.0188
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0051 0.0117
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0021 0.0066
Toxoplasma gondii patched family protein 0.0019 0.0015 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0143 0.0141
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0247 0.0701 0.1604
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0021 0.0021 0.0047
Schistosoma mansoni chromobox protein 0.0069 0.0167 0.0383
Loa Loa (eye worm) hypothetical protein 0.0033 0.0058 0.019
Toxoplasma gondii proteasome regulatory subunit 0.0021 0.0022 0.003
Trypanosoma brucei histone deacetylase 1 0.0842 0.2493 0.8286
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0028 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0058 0.0133
Brugia malayi protein C24B5.3 0.0019 0.0015 0.0042
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.03 0.0996
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0615 0.181 0.259
Trypanosoma brucei histone deacetylase 4 0.1013 0.3008 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0132 0.0356 0.0354
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Echinococcus multilocularis histone deacetylase 3 0.0842 0.2493 0.2492
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0025 0.0078
Toxoplasma gondii ATPase, AAA family protein 0.0041 0.0082 0.0117
Loa Loa (eye worm) hypothetical protein 0.0043 0.0089 0.0292
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.0472 0.3256
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0051 0.0142
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Loa Loa (eye worm) CAMK protein kinase 0.0016 0.0008 0.0023
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0192 0.0538 0.1785
Brugia malayi CLC chloride channel protein 0.0021 0.0021 0.0063
Brugia malayi Calcitonin receptor-like protein seb-1 0.031 0.0891 0.2958
Loa Loa (eye worm) hypothetical protein 0.019 0.053 0.1761
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0039 0.0075 0.0241
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0103 0.0269 0.0735
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0269 0.0891
Giardia lamblia Kinase, NEK 0.0022 0.0024 0.0069
Schistosoma mansoni hypothetical protein 0.0098 0.0254 0.0581
Echinococcus granulosus cyclin dependent kinase 5 0.005 0.0108 0.0244
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0089 0.0202
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0081 0.0202 0.0464
Trichomonas vaginalis histone deacetylase, putative 0.0842 0.2493 1
Trypanosoma brucei unspecified product 0.009 0.0228 0.0756
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0065 0.0063
Trypanosoma cruzi histone deacetylase, putative 0.0422 0.1228 0.4081
Toxoplasma gondii patched family protein 0.0019 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0919 0.2726 0.9059
Onchocerca volvulus 0.0019 0.0015 0.0087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0053 0.0186
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0023 0.0026 0.0024
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0087 0.0221 0.073
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0043 0.0087 0.0096
Brugia malayi ancient conserved domain protein 2 0.0021 0.0021 0.0063
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Loa Loa (eye worm) hypothetical protein 0.0094 0.0243 0.0804
Echinococcus multilocularis protoporphyrinogen oxidase 0.0043 0.0089 0.0087
Leishmania major protein kinase, putative 0.0022 0.0024 0.0077
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0051 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0051 0.0163
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0051 0.0177
Loa Loa (eye worm) hypothetical protein 0.0087 0.0219 0.0725
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0021 0.0043
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0025 0.0081
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0078 0.0253
Schistosoma mansoni topbp1 0.0041 0.0082 0.0188
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0022 0.0024 0.0077
Brugia malayi ancient conserved domain protein 4 0.0021 0.0021 0.0063
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0074 0.1066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0269
Echinococcus multilocularis dna polymerase eta 0.0157 0.043 0.0428
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0078 0.0286
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0027 0.0034
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0043 0.0087 0.0197
Onchocerca volvulus 0.003 0.005 0.0333
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.017 0.0471 0.1836
Schistosoma mansoni gabp alpha 0.0073 0.0178 0.0408
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0143 0.039 0.1295
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Brugia malayi Histone deacetylase family protein 0.1013 0.3008 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0289 0.0827 0.33
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0209 0.0588 0.0586
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0074 0.0072
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0025 0.0081
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0043 0.0087 0.0197
Leishmania major mitochondrial DNA polymerase beta 0.0619 0.1823 0.606
Schistosoma mansoni serine/threonine protein kinase 0.0192 0.0538 0.1233
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0078 0.017
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0414 0.095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0051 0.0049
Giardia lamblia Flap structure-specific endonuclease 0.0055 0.0125 0.0476
Brugia malayi jmjC domain containing protein 0.0061 0.0143 0.0471
Echinococcus granulosus dual specificity 0.0192 0.0538 0.1229
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0383 0.0381
Echinococcus granulosus neuroglian 0.0023 0.0026 0.0056
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.017 0.047 0.1074
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0146 0.0398 0.0546
Brugia malayi Myosin head containing protein 0.0019 0.0015 0.0042
Schistosoma mansoni DNA polymerase IV / kappa 0.004 0.008 0.0183
Trypanosoma cruzi DNA polymerase eta, putative 0.0157 0.043 0.1427
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0016 0.0007 0.0005
Leishmania major histone deacetylase, putative 0.1013 0.3008 1
Toxoplasma gondii histone deacetylase HDAC2 0.0842 0.2493 0.3597
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0051 0.0112
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0039 0.0075 0.0247
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Loa Loa (eye worm) DR-78 0.0014 0.0002 0.0004
Echinococcus granulosus defective proboscis extension response 0.0036 0.0067 0.015
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0051 0.0163
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0087 0.0197
Brugia malayi BRCA1-associated protein 2 containing protein 0.0019 0.0016 0.0046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0383 0.0879
Trypanosoma cruzi DNA damage repair protein, putative 0.004 0.008 0.0263
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0051 0.0177
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0021
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0081 0.0265
Brugia malayi 6-phosphofructokinase 0.0114 0.03 0.0993
Trypanosoma brucei unspecified product 0.009 0.0228 0.0756
Echinococcus granulosus neuroglian 0.0048 0.0104 0.0233
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0021 0.0063
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0247 0.0701 0.0699
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0025 0.0073
Echinococcus multilocularis Niemann Pick C1 protein 0.044 0.1282 0.1281
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0002 0.0005
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0043 0.0137
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0051 0.0339
Echinococcus granulosus peroxidasin 0.0023 0.0026 0.0056
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0027 0.0038
Echinococcus granulosus histone deacetylase 7 0.1013 0.3008 0.6898
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0087 0.0219 0.0722
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0051 0.0163
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0025 0.0032
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0008 0.0023
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0192 0.0538 0.1785
Plasmodium falciparum protein kinase 5 0.005 0.0108 0.0152
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Loa Loa (eye worm) hypothetical protein 0.0053 0.0118 0.039
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0159 0.0359
Brugia malayi serine/threonine kinase 12 0.017 0.0471 0.1559
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0051 0.0163
Brugia malayi jmjC domain containing protein 0.0066 0.0159 0.0521
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0081 0.0202 0.0538
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0039 0.0075 0.0247
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0023
Trypanosoma cruzi cdc2-related kinase 1 0.005 0.0108 0.0357
Echinococcus granulosus roundabout 2 0.0023 0.0026 0.0056
Loa Loa (eye worm) hypothetical protein 0.0479 0.1401 0.4656
Loa Loa (eye worm) hypothetical protein 0.0437 0.1275 0.4237
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0842 0.2493 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0619 0.1823 0.606
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0178 0.0403
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0021 0.0021 0.0029
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0043 0.0087 0.0125
Trichomonas vaginalis helicase, putative 0.002 0.0019 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0326 0.0941 0.2726
Toxoplasma gondii ck2 beta subunit 0.0039 0.0075 0.0107
Brugia malayi RE40412p 0.0015 0.0003 0.0004
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0043 0.0089 0.0204
Brugia malayi Ets-domain containing protein 0.0073 0.0178 0.0586
Schistosoma mansoni hypothetical protein 0.0127 0.0342 0.0783
Schistosoma mansoni hypothetical protein 0.0127 0.0342 0.0783
Brugia malayi glutaminase DH11.1 0.0561 0.1647 0.5472
Echinococcus multilocularis cyclin dependent kinase 5 0.005 0.0108 0.0106
Plasmodium vivax histone deacetylase, putative 0.1013 0.3008 0.4339
Echinococcus granulosus tyrosine protein kinase otk 0.0023 0.0026 0.0056
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0043 0.0087 0.0096
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0008 0.0007
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.0009 0.0007
Brugia malayi steroid hormone receptor 0.0031 0.0051 0.0163
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0741 0.2954
Echinococcus granulosus bloom syndrome protein 0.0021 0.0021 0.0043
Brugia malayi phosphofructokinase 0.0114 0.03 0.0993
Brugia malayi chloride channel protein 7 0.0021 0.0021 0.0063
Loa Loa (eye worm) TK/ROR protein kinase 0.0034 0.0062 0.0203
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0022 0.0025 0.0035
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0051 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0024 0.0069
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0025 0.0081
Trypanosoma cruzi histone deacetylase 1, putative 0.0842 0.2493 0.8286
Toxoplasma gondii zinc finger cdgsh type protein 0.0015 0.0003 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0146 0.0398 0.1316
Brugia malayi Muscleblind-like protein 0.0919 0.2726 0.9059
Entamoeba histolytica protein kinase , putative 0.017 0.0471 0.1836
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0008 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0383 0.0875
Schistosoma mansoni smad1 5 8 and 0.0025 0.0033 0.0075
Schistosoma mansoni lozenge 0.0055 0.0124 0.0283
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0026 0.0082
Trypanosoma brucei histone deacetylase 3 0.1013 0.3008 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0053 0.0186
Schistosoma mansoni histone deacetylase 0.0842 0.2493 0.5717
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0101 0.0262 0.0716
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.03 0.115
Toxoplasma gondii patched family protein 0.0019 0.0015 0.002
Loa Loa (eye worm) IMP dehydrogenase 1 0.0021 0.0021 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Plasmodium vivax DNA repair protein REV1, putative 0.004 0.008 0.0111
Trichomonas vaginalis replication factor C large subunit, putative 0.0041 0.0082 0.0302
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.03 0.0829
Trypanosoma brucei DNA damage repair protein, putative 0.004 0.008 0.0263
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0159 0.0524
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Echinococcus multilocularis histone deacetylase 8 0.0422 0.1228 0.1227
Giardia lamblia Kinase, CAMK CAMKL 0.0049 0.0105 0.0395
Echinococcus granulosus sterol regulatory element binding protein 0.0132 0.0356 0.0812
Leishmania major DNA polymerase eta, putative 0.0067 0.016 0.0529
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0087 0.0197
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0043 0.0089 0.0124
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0051 0.0177
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0043 0.0087 0.029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0085
Loa Loa (eye worm) pigment dispersing factor receptor c 0.031 0.0891 0.296
Echinococcus multilocularis muscleblind protein 1 0.0919 0.2726 0.2724
Brugia malayi Smad1 0.0025 0.0033 0.0103
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0021 0.0021 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0113 0.0427
Echinococcus granulosus serine:threonine protein kinase Nek1 0.0017 0.0011 0.002
Trichomonas vaginalis AGC family protein kinase 0.017 0.0471 0.1865
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0019 0.0016 0.0021
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.03 0.0685
Echinococcus multilocularis chromobox protein 1 0.0069 0.0167 0.0165
Echinococcus granulosus chromobox protein 1 0.0069 0.0167 0.0379
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0113 0.0373
Echinococcus multilocularis tyrosine protein kinase otk 0.0023 0.0026 0.0024
Onchocerca volvulus Histone deacetylase 10 homolog 0.0422 0.1228 0.8498
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0021 0.0021 0.0066
Loa Loa (eye worm) hypothetical protein 0.0157 0.043 0.1427
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0034 0.011
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0051 0.0117
Echinococcus multilocularis snurportin 1 0.033 0.0954 0.0952
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0132 0.0356 0.118
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0472 0.1871
Echinococcus granulosus H:Cl exchange transporter 3 0.0021 0.0021 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0051 0.0049
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0026 0.0061
Echinococcus granulosus dna polymerase eta 0.0157 0.043 0.0982
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0021 0.0022 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0051 0.0117
Onchocerca volvulus 0.0021 0.0021 0.013
Brugia malayi tailless protein 0.0014 0.0002 0.0001
Schistosoma mansoni DNA ligase IV 0.0041 0.0082 0.0188
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.03 0.0405
Echinococcus multilocularis chromobox protein 1 0.0069 0.0167 0.0165
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0087 0.0284
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Toxoplasma gondii CBS domain-containing protein 0.0021 0.0021 0.0029
Brugia malayi nuclear receptor NHR-67 0.0014 0.0002 0.0001
Onchocerca volvulus 0.0158 0.0434 0.2992
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0021 0.0029
Echinococcus granulosus replication factor c subunit 1 0.0041 0.0082 0.0183
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0053 0.0186
Onchocerca volvulus 0.0043 0.0087 0.0591
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0555 0.163 0.3735
Loa Loa (eye worm) hypothetical protein 0.0045 0.0095 0.0313
Echinococcus multilocularis nibrin 0.0041 0.0082 0.008
Trichomonas vaginalis set domain proteins, putative 0.0249 0.0709 0.2826
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0051 0.0177
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0055 0.0125 0.0179
Loa Loa (eye worm) RNA binding protein 0.0251 0.0715 0.2375
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0108 0.0357
Echinococcus granulosus lachesin 0.0023 0.0026 0.0056
Echinococcus multilocularis intestinal type alkaline phosphatase 0.017 0.047 0.0468
Leishmania major DNA polymerase eta, putative 0.0157 0.043 0.1427
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0043 0.0087 0.0287
Schistosoma mansoni neuroglian 0.0023 0.0026 0.0061
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.0011 0.0012
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0025 0.0023
Toxoplasma gondii propionate-CoA ligase 0.0043 0.0087 0.0125
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0008 0.0023
Leishmania major hypothetical protein, conserved 0.0078 0.0192 0.0635
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0043 0.0089 0.0098
Plasmodium falciparum protein MAM3, putative 0.0021 0.0021 0.0025
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0022 0.0024 0.003
Toxoplasma gondii histone deacetylase HDAC4 0.0422 0.1228 0.1772
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0033 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Schistosoma mansoni hypothetical protein 0.0036 0.0065 0.015
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0021 0.0066
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0011 0.0015
Schistosoma mansoni protein kinase 0.017 0.0471 0.1079
Echinococcus multilocularis replication factor c subunit 1 0.0041 0.0082 0.008
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0021 0.0021 0.0066
Brugia malayi hypothetical protein 0.0014 0.0002 0.0001
Onchocerca volvulus Alicorn homolog 0.0098 0.0252 0.1733
Echinococcus multilocularis peroxidasin 0.0023 0.0026 0.0024
Echinococcus multilocularis BC026374 protein (S09 family) 0.0081 0.0202 0.02
Plasmodium vivax histone deacetylase 1, putative 0.0842 0.2493 0.3595
Echinococcus granulosus lysine specific histone demethylase 1A 0.0043 0.0089 0.0199
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0049 0.0105 0.0103
Leishmania major importin beta-1 subunit, putative 0.0025 0.0034 0.011
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0051 0.0044
Schistosoma mansoni apoptosis regulator bax 0.0087 0.0219 0.0502
Trichomonas vaginalis antibiotic synthetase, putative 0.0043 0.0087 0.0324
Giardia lamblia Hypothetical protein 0.0021 0.0021 0.0056
Onchocerca volvulus 0.0019 0.0015 0.0087
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0016 0.0007 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0251 0.0715 0.164
Leishmania major DNA polymerase kappa, putative 0.0143 0.039 0.1295
Brugia malayi nuclear hormone receptor 0.0014 0.0002 0.0001
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0092 0.0132
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0007
Echinococcus multilocularis dna polymerase kappa 0.0184 0.0513 0.0511
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0051 0.0166
Trichomonas vaginalis glucosylceramidase, putative 0.026 0.0741 0.2954
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.0232 0.0625
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0051 0.0112
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.03 0.0829
Brugia malayi MH2 domain containing protein 0.0025 0.0033 0.0103
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0192 0.0538 0.1785
Echinococcus granulosus snurportin 1 0.033 0.0954 0.2183
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0051 0.0117
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1141 0.3396 1
Treponema pallidum Mg2+ transport protein (mgtE) 0.0021 0.0021 0.024
Brugia malayi protein C24B5.3 0.0019 0.0015 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0472 0.1871
Echinococcus multilocularis Protein lozenge 0.0055 0.0124 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0184 0.0513 0.1702
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0078 0.0286
Loa Loa (eye worm) patched family protein 0.0019 0.0015 0.0045
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0043 0.0087 0.0197
Trypanosoma brucei GMP reductase 0.0021 0.0021 0.0066
Brugia malayi nuclear receptor RXR 0.0016 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0051 0.0166
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0272 0.0778 0.1785
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0078 0.0179
Echinococcus multilocularis histone deacetylase 1 0.0842 0.2493 0.2492
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0192 0.0276
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.019 0.053 0.3661
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.03 0.0996
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.017 0.0471 0.1836
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0089 0.0124
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0002 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0053 0.0186
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0044 0.0097
Leishmania major GTP-binding protein, putative 0.0023 0.0027 0.0087
Onchocerca volvulus 0.0043 0.0087 0.0591
Loa Loa (eye worm) TK protein kinase 0.0017 0.0009 0.0027
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0146 0.0398 0.0546
Trichomonas vaginalis ran, putative 0.0023 0.0027 0.0081
Trypanosoma cruzi UDP-galactopyranose mutase 0.0043 0.0089 0.0292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0383 0.0879
Brugia malayi Patched family protein 0.0019 0.0015 0.0042
Onchocerca volvulus 0.0088 0.0225 0.1543
Plasmodium vivax serine/threonine protein kinase 6, putative 0.017 0.0471 0.0675
Echinococcus granulosus titin 0.0016 0.0008 0.0014
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0075 0.0276
Brugia malayi amine oxidase, flavin-containing family protein 0.0043 0.0089 0.0289
Giardia lamblia Kinase, CMGC CDK 0.005 0.0108 0.0408
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.033 0.0954 0.3167
Echinococcus granulosus aurora kinase A 0.017 0.0471 0.1075
Echinococcus granulosus importin subunit beta 1 0.0031 0.0052 0.0114
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.022
Echinococcus granulosus acetylcholinesterase 0.0479 0.1401 0.3211
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0041 0.0139
Echinococcus granulosus casein kinase ii subunit beta 0.0039 0.0075 0.0168
Brugia malayi Thioredoxin reductase 0.004 0.0078 0.0254
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.0146 0.0398 0.1319
Loa Loa (eye worm) hypothetical protein 0.0059 0.0135 0.0447
Echinococcus multilocularis histone deacetylase 7 0.1013 0.3008 0.3007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0053 0.0186
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0027 0.0081
Schistosoma mansoni terminal deoxycytidyl transferase 0.013 0.035 0.0803
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.022
Schistosoma mansoni hypothetical protein 0.0087 0.0219 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0025 0.0073
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0051 0.0177
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0054 0.012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0479 0.1401 0.4656
Schistosoma mansoni ap endonuclease 0.0038 0.0074 0.017
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0021 0.0043
Loa Loa (eye worm) hypothetical protein 0.0591 0.1739 0.5777
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0049 0.0105 0.0346
Brugia malayi histone deacetylase 11 0.0422 0.1228 0.4079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0045
Giardia lamblia Kinase, CMGC CDK 0.005 0.0108 0.0408
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0051 0.0117
Loa Loa (eye worm) hypothetical protein 0.0043 0.0087 0.0287
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0051 0.0163
Echinococcus granulosus para nitrobenzyl esterase 0.0081 0.0202 0.0459
Plasmodium falciparum chorismate synthase 0.2314 0.6929 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0087 0.0221 0.073
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0033 0.0071
Brugia malayi histone deacetylase 1 (HD1) 0.0842 0.2493 0.8286
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0051 0.0163
Schistosoma mansoni hypothetical protein 0.033 0.0954 0.2187
Schistosoma mansoni histone deacetylase hda2 0.1032 0.3066 0.703
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.05 0.1982
Echinococcus multilocularis acetylcholinesterase 0.0479 0.1401 0.14
Plasmodium vivax protein kinase Crk2 0.005 0.0108 0.0152
Toxoplasma gondii aurora kinase 0.017 0.0471 0.0678
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0022 0.0025 0.0058
Brugia malayi hypothetical protein 0.0041 0.0082 0.0266
Schistosoma mansoni hypothetical protein 0.0513 0.1503 0.3447
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0021 0.0021 0.0063
Brugia malayi Ets-domain containing protein 0.0073 0.0178 0.0586
Echinococcus granulosus tar DNA binding protein 0.0251 0.0715 0.1637
Loa Loa (eye worm) histone deacetylase 1 0.0842 0.2493 0.8286
Brugia malayi hypothetical protein 0.0036 0.0065 0.0211
Trichomonas vaginalis flap endonuclease-1, putative 0.0055 0.0125 0.0476
Echinococcus granulosus roundabout 2 0.0059 0.0135 0.0306
Brugia malayi jmjC domain containing protein 0.0016 0.0008 0.002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0008 0.0018
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0075 0.0276
Plasmodium falciparum protoporphyrinogen oxidase 0.0043 0.0089 0.0124
Brugia malayi putative serine/threonine kinase SADA gamma 0.0049 0.0105 0.0343
Trichomonas vaginalis antibiotic synthetase, putative 0.0043 0.0087 0.0324
Trichomonas vaginalis AGC family protein kinase 0.017 0.0471 0.1865
Loa Loa (eye worm) hypothetical protein 0.0109 0.0287 0.095
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0021 0.0022 0.0067
Entamoeba histolytica acyl-CoA synthetase, putative 0.0146 0.0398 0.1542
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0074 0.0243
Onchocerca volvulus 0.0019 0.0015 0.0087
Schistosoma mansoni neuroligin 3 (S09 family) 0.0081 0.0202 0.0464
Loa Loa (eye worm) hypothetical protein 0.0036 0.0067 0.022
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0043 0.0087 0.0196
Loa Loa (eye worm) hypothetical protein 0.0081 0.0202 0.0669
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0383 0.1073
Echinococcus granulosus H:Cl exchange transporter 7 0.0021 0.0021 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0051 0.0166
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0101 0.0262 0.0716
Brugia malayi Carboxylesterase family protein 0.0081 0.0202 0.0666
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0021 0.0056
Toxoplasma gondii histone deacetylase HDAC1 0.1013 0.3008 0.4341
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0041 0.0082 0.0117
Brugia malayi Histone deacetylase 1 0.0842 0.2493 0.8286
Brugia malayi latrophilin 2 splice variant baaae 0.0212 0.0596 0.1976
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0619 0.1823 0.606
Onchocerca volvulus 0.0019 0.0015 0.0087
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0034 0.011
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0043 0.0089 0.0202
Plasmodium falciparum casein kinase II beta chain 0.0039 0.0075 0.0104
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.1181
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0078 0.0257
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0051 0.0069
Schistosoma mansoni alkaline phosphatase 0.017 0.047 0.1078
Mycobacterium tuberculosis Carboxylesterase LipT 0.0081 0.0202 0.0538
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0272 0.0778 0.1781
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0024 0.0055
Brugia malayi Patched related family protein 4 0.0019 0.0015 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0105 0.0395
Echinococcus granulosus intestinal type alkaline phosphatase 0.017 0.047 0.1074
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0092 0.0345
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0036 0.0067 0.0154

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 500 uM Inhibition of BACE1 after 2 hrs by FRET assay ChEMBL. 20378363

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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