Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | exported lipase 2 | 0.0022 | 0.0057 | 0.0089 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.0116 | 1 |
Schistosoma mansoni | family S9 unassigned peptidase (S09 family) | 0.0022 | 0.0057 | 0.1114 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0196 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0085 | 0.0085 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.008 | 0.0538 | 0.7929 |
Loa Loa (eye worm) | hypothetical protein | 0.1214 | 1 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0116 | 1 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0116 | 0.2274 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0196 | 0.0196 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0027 | 0.0094 | 0.0094 |
Plasmodium vivax | PST-A protein | 0.0022 | 0.0057 | 0.0089 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0027 | 0.0094 | 0.0094 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0085 | 0.0092 |
Schistosoma mansoni | thyroid hormone receptor | 0.0027 | 0.0094 | 0.184 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0027 | 0.0094 | 0.1389 |
Plasmodium vivax | unspecified product | 0.0022 | 0.0057 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.003 | 0.003 |
Plasmodium vivax | hypothetical protein, conserved | 0.0022 | 0.0057 | 0.0089 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0196 | 0.0464 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0381 | 0.305 | 1 |
Plasmodium vivax | lysophospholipase, putative | 0.0022 | 0.0057 | 0.0089 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0027 | 0.0094 | 0.1389 |
Plasmodium vivax | lysophospholipase, putative | 0.0022 | 0.0057 | 0.0089 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0027 | 0.0094 | 0.0094 |
Brugia malayi | bZIP transcription factor family protein | 0.0091 | 0.0631 | 0.0631 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0196 | 0.0464 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0027 | 0.0094 | 0.0094 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0097 | 0.0678 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0381 | 0.305 | 1 |
Plasmodium falciparum | alpha/beta-hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0196 | 0.3828 |
Echinococcus multilocularis | peregrin | 0.003 | 0.0116 | 0.1717 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0027 | 0.0094 | 0.0094 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0085 | 0.018 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0027 | 0.0094 | 0.0094 |
Brugia malayi | jmjC domain containing protein | 0.0097 | 0.0678 | 0.0678 |
Plasmodium falciparum | prodrug activation and resistance esterase | 0.0022 | 0.0057 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.003 | 0.003 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0085 | 0.018 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0027 | 0.0094 | 0.0094 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0085 | 0.0085 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0381 | 0.305 | 1 |
Echinococcus granulosus | jun protein | 0.0091 | 0.0631 | 0.9312 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0085 | 0.0092 |
Echinococcus granulosus | Phospholipase carboxylesterase | 0.0022 | 0.0057 | 0.0841 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0016 | 0.0000000075621 | 0.00000014773 |
Echinococcus multilocularis | Phospholipase carboxylesterase | 0.0022 | 0.0057 | 0.0841 |
Plasmodium vivax | lysophospholipase, putative | 0.0022 | 0.0057 | 0.0089 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0027 | 0.0094 | 0.1389 |
Brugia malayi | Uncoordinated protein 44 | 0.0016 | 0.0000000075621 | 0.0000000075621 |
Plasmodium vivax | PST-A protein | 0.0381 | 0.305 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0001 | 0.0001 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0085 | 0.0092 |
Schistosoma mansoni | jumonji domain containing protein | 0.0077 | 0.0512 | 1 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0468 | 0.0468 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0027 | 0.0094 | 0.1389 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0213 | 0.3143 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0091 | 0.0631 | 0.9312 |
Echinococcus granulosus | abhydrolase domain containing 3 | 0.0022 | 0.0057 | 0.0841 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0085 | 0.018 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0027 | 0.0094 | 0.184 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0381 | 0.305 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0085 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0057 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0027 | 0.0094 | 0.1389 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0091 | 0.0631 | 0.9312 |
Plasmodium falciparum | alpha/beta hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Mycobacterium ulcerans | lysophospholipase | 0.0381 | 0.305 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0168 | 0.2483 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0016 | 0.0001 | 0.0022 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0381 | 0.305 | 1 |
Plasmodium vivax | PST-A protein | 0.0022 | 0.0057 | 0.0089 |
Mycobacterium ulcerans | hypothetical protein | 0.0022 | 0.0057 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0085 | 0.0209 |
Plasmodium falciparum | lysophospholipase, putative | 0.0022 | 0.0057 | 0.0089 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0027 | 0.0094 | 0.184 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0116 | 0.0116 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0213 | 0.3143 |
Schistosoma mansoni | jun-related protein | 0.0074 | 0.0489 | 0.9547 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0116 | 0.0116 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0027 | 0.0094 | 0.2014 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Plasmodium falciparum | lysophospholipase, putative | 0.0381 | 0.305 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0116 | 1 |
Plasmodium falciparum | alpha/beta hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0085 | 0.018 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0085 | 0.018 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.0094 | 0.1389 |
Plasmodium falciparum | epoxide hydrolase 2 | 0.0022 | 0.0057 | 0.0089 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.0094 | 0.1389 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0057 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0085 | 0.0092 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0085 | 0.018 |
Plasmodium vivax | PST-A protein | 0.0022 | 0.0057 | 0.0089 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0027 | 0.0094 | 0.2014 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0085 | 0.0092 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0027 | 0.0094 | 0.1389 |
Mycobacterium ulcerans | hypothetical protein | 0.0022 | 0.0057 | 0.0089 |
Mycobacterium ulcerans | hypothetical protein | 0.0381 | 0.305 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0027 | 0.0094 | 0.0094 |
Echinococcus granulosus | peregrin | 0.003 | 0.0116 | 0.1717 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0085 | 0.018 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.0094 | 0.1389 |
Schistosoma mansoni | thyroid hormone receptor | 0.0027 | 0.0094 | 0.184 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0196 | 0.289 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.003 | 0.003 |
Onchocerca volvulus | 0.0027 | 0.0094 | 0.2014 | |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0381 | 0.305 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0085 | 0.0209 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0116 | 0.2274 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0381 | 0.305 | 1 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0381 | 0.305 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0027 | 0.0094 | 0.184 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0168 | 0.3289 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0196 | 0.289 |
Plasmodium falciparum | esterase, putative | 0.0381 | 0.305 | 1 |
Plasmodium vivax | PST-A protein | 0.0022 | 0.0057 | 0.0089 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0027 | 0.0094 | 0.0094 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0027 | 0.0094 | 0.184 |
Echinococcus multilocularis | Ankyrin | 0.0016 | 0.0001 | 0.0016 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0116 | 0.1717 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0381 | 0.305 | 1 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.008 | 0.0538 | 0.7929 |
Echinococcus granulosus | monoacylglycerol lipase abhd12 | 0.0022 | 0.0057 | 0.0841 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0293 | 0.0293 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0057 |
Echinococcus granulosus | Ankyrin | 0.0016 | 0.0001 | 0.0016 |
Echinococcus granulosus | abhydrolase domain containing protein 13 | 0.0022 | 0.0057 | 0.0841 |
Plasmodium falciparum | lysophospholipase, putative | 0.0381 | 0.305 | 1 |
Plasmodium falciparum | BEM46-like protein, putative | 0.0022 | 0.0057 | 0.0089 |
Schistosoma mansoni | family S9 unassigned peptidase (S09 family) | 0.0022 | 0.0057 | 0.1114 |
Plasmodium falciparum | lysophospholipase, putative | 0.0022 | 0.0057 | 0.0089 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0027 | 0.0094 | 0.2014 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0027 | 0.0094 | 0.1389 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0116 | 0.0116 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0381 | 0.305 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0027 | 0.0094 | 0.1389 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0027 | 0.0094 | 0.0094 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0027 | 0.0094 | 0.184 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0027 | 0.0094 | 0.1389 |
Echinococcus multilocularis | jun protein | 0.0091 | 0.0631 | 0.9312 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0027 | 0.0094 | 0.184 |
Plasmodium falciparum | alpha/beta hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Plasmodium vivax | hypothetical protein, conserved | 0.0022 | 0.0057 | 0.0089 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0027 | 0.0094 | 0.184 |
Echinococcus multilocularis | monoacylglycerol lipase abhd12 | 0.0022 | 0.0057 | 0.0841 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0027 | 0.0094 | 0.1389 |
Brugia malayi | nuclear receptor NHR-88 | 0.0027 | 0.0094 | 0.0094 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0381 | 0.305 | 1 |
Plasmodium vivax | PST-A protein | 0.0022 | 0.0057 | 0.0089 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0027 | 0.0094 | 0.0094 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0027 | 0.0094 | 0.1389 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0027 | 0.0094 | 0.184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0027 | 0.0094 | 0.0094 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0027 | 0.0094 | 0.0094 |
Chlamydia trachomatis | acyltransferase family protein | 0.0022 | 0.0057 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0196 | 0.3828 |
Plasmodium vivax | hypothetical protein, conserved | 0.0022 | 0.0057 | 0.0089 |
Echinococcus multilocularis | abhydrolase domain containing 3 | 0.0022 | 0.0057 | 0.0841 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0027 | 0.0094 | 0.184 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.0094 | 0.1389 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0027 | 0.0094 | 0.1389 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0016 | 0.0000000075621 | 0.00000011153 |
Plasmodium vivax | alpha/beta hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Plasmodium falciparum | exported lipase 1 | 0.0022 | 0.0057 | 0.0089 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0168 | 0.2483 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0611 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Onchocerca volvulus | 0.0072 | 0.0468 | 1 | |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0116 | 0.1717 |
Brugia malayi | Protein kinase domain containing protein | 0.0016 | 0.0000000075621 | 0.0000000075621 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0381 | 0.305 | 1 |
Mycobacterium ulcerans | hydrolase | 0.0022 | 0.0057 | 0.0089 |
Plasmodium falciparum | alpha/beta hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Brugia malayi | nuclear hormone receptor | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0379 | 0.0379 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0027 | 0.0094 | 0.0094 |
Plasmodium falciparum | alpha/beta hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Brugia malayi | steroid hormone receptor | 0.0027 | 0.0094 | 0.0094 |
Onchocerca volvulus | 0.0026 | 0.0085 | 0.181 | |
Schistosoma mansoni | coup transcription factor | 0.0027 | 0.0094 | 0.184 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0381 | 0.305 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0168 | 0.0168 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0027 | 0.0094 | 0.0094 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0381 | 0.305 | 1 |
Brugia malayi | MGC83647 protein | 0.0022 | 0.0057 | 0.0057 |
Leishmania major | hypothetical protein, conserved | 0.0022 | 0.0057 | 0.000000025268 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0027 | 0.0094 | 0.1389 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0016 | 0.0000000075621 | 0.00000011153 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0116 | 0.0116 |
Brugia malayi | Protein C20orf22 | 0.0022 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0057 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0027 | 0.0094 | 0.184 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0027 | 0.0094 | 0.1389 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0381 | 0.305 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0085 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0057 | 0.0057 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0116 | 0.0285 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0085 | 0.0085 |
Brugia malayi | ecdysteroid receptor | 0.0027 | 0.0094 | 0.0094 |
Chlamydia trachomatis | hydrolase | 0.0022 | 0.0057 | 1 |
Plasmodium falciparum | esterase, putative | 0.0022 | 0.0057 | 0.0089 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0168 | 0.0168 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.0116 | 0.2489 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.003 | 0.003 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0027 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.003 | 0.003 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0027 | 0.0094 | 0.0094 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0116 | 0.0285 |
Leishmania major | monoglyceride lipase, putative | 0.0381 | 0.305 | 1 |
Plasmodium vivax | unspecified product | 0.0022 | 0.0057 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0489 | 0.9547 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0168 | 0.3289 |
Plasmodium falciparum | alpha/beta hydrolase fold domain containing protein, putative | 0.0022 | 0.0057 | 0.0089 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.0057 | 0.0117 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0097 | 0.0678 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0085 | 0.0085 |
Brugia malayi | Death domain containing protein | 0.0016 | 0.0000000075621 | 0.0000000075621 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0027 | 0.0094 | 0.0094 |
Plasmodium falciparum | esterase, putative | 0.0022 | 0.0057 | 0.0089 |
Brugia malayi | MGC79044 protein | 0.0022 | 0.0057 | 0.0057 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.003 | 0.0029 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0027 | 0.0094 | 0.0094 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0085 | 0.0085 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0196 | 0.0464 |
Plasmodium falciparum | lysophospholipase, putative | 0.0381 | 0.305 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0094 | 0.0094 |
Schistosoma mansoni | peptidase | 0.0022 | 0.0057 | 0.1114 |
Plasmodium vivax | alpha/beta hydrolase, putative | 0.0022 | 0.0057 | 0.0089 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 830 uM | Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 0.01% Triton-X by HPLC | ChEMBL. | 25036789 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.