Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | epsilon tubulin, putative | 0.007 | 0.3277 | 0.2999 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Trypanosoma brucei | SUMO1/Ulp2, putative | 0.0039 | 0.1384 | 0.1028 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0031 | 0.0855 | 0.0548 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0093 | 0.4685 | 0.4326 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0093 | 0.4685 | 0.4466 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.007 | 0.3277 | 0.3051 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0903 | 0.0527 |
Onchocerca volvulus | 0.004 | 0.1418 | 1 | |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0181 | 1 | 1 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | tubulin alpha | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.007 | 0.3277 | 0.3051 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0031 | 0.0855 | 0.0236 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | serine/threonine protein phosphatase 5 | 0.0022 | 0.0324 | 0.0019 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0855 | 0.0236 |
Trypanosoma cruzi | alpha tubulin, putative | 0.007 | 0.3277 | 0.2999 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0176 | 0.9702 | 0.9654 |
Brugia malayi | alpha-tubulin | 0.007 | 0.3277 | 0.3277 |
Schistosoma mansoni | tubulin subunit beta | 0.0181 | 1 | 1 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | tubulin subunit beta | 0.0181 | 1 | 1 |
Trichomonas vaginalis | tubulin, putative | 0.004 | 0.1418 | 0.0837 |
Echinococcus multilocularis | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0551 | 0.0235 |
Loa Loa (eye worm) | tubulin beta chain | 0.0031 | 0.0855 | 0.0566 |
Trypanosoma brucei | alpha tubulin | 0.007 | 0.3277 | 0.2999 |
Schistosoma mansoni | tubulin subunit beta | 0.0181 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Trypanosoma cruzi | hypothetical protein | 0.0093 | 0.4685 | 0.4466 |
Echinococcus multilocularis | tubulin subunit TubB | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | tubulin alpha | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0903 | 0.0616 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | caspase 8 | 0.0027 | 0.0634 | 0.032 |
Loa Loa (eye worm) | BEN-1 protein | 0.0181 | 1 | 1 |
Leishmania major | zeta tubulin, putative | 0.0031 | 0.0855 | 0.0548 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.007 | 0.3277 | 0.2822 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.007 | 0.3277 | 0.2822 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.007 | 0.3277 | 0.3051 |
Schistosoma mansoni | SET domain protein | 0.0033 | 0.1018 | 0.0647 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1061 | 0.0779 |
Echinococcus granulosus | caspase | 0.0101 | 0.5121 | 0.4957 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Echinococcus multilocularis | caspase | 0.0101 | 0.5121 | 0.4957 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0101 | 0.5121 | 0.4957 |
Schistosoma mansoni | cell adhesion molecule | 0.003 | 0.0827 | 0.0448 |
Echinococcus multilocularis | histone lysine N methyltransferase NSD3 | 0.0033 | 0.1018 | 0.0717 |
Trypanosoma cruzi | metacaspase, putative | 0.0027 | 0.0634 | 0.0247 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0181 | 1 | 1 |
Echinococcus multilocularis | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.007 | 0.3277 | 0.3051 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.3115 | 0.2831 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.007 | 0.3277 | 0.2822 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0039 | 0.1384 | 0.0801 |
Brugia malayi | Tubulin beta chain | 0.0031 | 0.0855 | 0.0855 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0551 | 0.0551 |
Schistosoma mansoni | tubulin subunit beta | 0.0181 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0551 | 0.0161 |
Schistosoma mansoni | tubulin subunit beta | 0.0181 | 1 | 1 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.007 | 0.3277 | 0.3051 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Mycobacterium ulcerans | cell division protein FtsZ | 0.0031 | 0.0855 | 0.5 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.007 | 0.3277 | 0.2822 |
Plasmodium falciparum | sentrin-specific protease 1 | 0.0039 | 0.1384 | 0.1095 |
Loa Loa (eye worm) | BEN-1 protein | 0.0181 | 1 | 1 |
Trypanosoma brucei | alpha tubulin | 0.007 | 0.3277 | 0.2999 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.007 | 0.3277 | 0.3051 |
Plasmodium falciparum | alpha tubulin 1 | 0.007 | 0.3277 | 0.3051 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0039 | 0.1384 | 0.1384 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0551 | 0.0253 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0181 | 1 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0903 | 0.0598 |
Trichomonas vaginalis | tubulin, putative | 0.004 | 0.1418 | 0.0837 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C48, putative | 0.0039 | 0.1384 | 0.1028 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus multilocularis | sentrin specific protease 1 | 0.0039 | 0.1384 | 0.1095 |
Treponema pallidum | cell division protein FtsZ | 0.0031 | 0.0855 | 0.5 |
Trichomonas vaginalis | tubulin beta-1 chain, putative | 0.0031 | 0.0855 | 0.0236 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0039 | 0.1384 | 0.0801 |
Giardia lamblia | Alpha-tubulin | 0.007 | 0.3277 | 0.2648 |
Plasmodium vivax | sentrin-specific protease 1, putative | 0.0039 | 0.1384 | 0.1095 |
Plasmodium vivax | tubulin alpha chain, putative | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus granulosus | defective proboscis extension response | 0.0026 | 0.0602 | 0.0288 |
Echinococcus granulosus | tubulin epsilon chain | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0855 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1384 | 0.1112 |
Plasmodium falciparum | tubulin delta chain, putative | 0.0031 | 0.0855 | 0.0548 |
Echinococcus granulosus | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Leishmania major | gamma-tubulin | 0.007 | 0.3277 | 0.3051 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.007 | 0.3277 | 0.2822 |
Trypanosoma brucei | zeta tubulin | 0.0031 | 0.0855 | 0.0477 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0903 | 0.0598 |
Trypanosoma brucei | metacaspase MCA2 | 0.0027 | 0.0634 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1384 | 0.1112 |
Loa Loa (eye worm) | alpha-tubulin | 0.007 | 0.3277 | 0.3064 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0551 | 0.0235 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0903 | 0.0598 |
Plasmodium falciparum | tubulin epsilon chain, putative | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0181 | 1 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.007 | 0.3277 | 0.2999 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | beta tubulin | 0.0181 | 1 | 1 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0093 | 0.4685 | 0.4685 |
Echinococcus multilocularis | roundabout 2 | 0.0034 | 0.1061 | 0.0762 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0551 | 0.0161 |
Trypanosoma brucei | beta tubulin | 0.007 | 0.3277 | 0.2999 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.007 | 0.3277 | 0.3051 |
Trypanosoma brucei | epsilon tubulin | 0.007 | 0.3277 | 0.2999 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0093 | 0.4685 | 0.4326 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Schistosoma mansoni | tubulin subunit gamma | 0.007 | 0.3277 | 0.2999 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0026 | 0.0602 | 0.0215 |
Schistosoma mansoni | alpha tubulin | 0.007 | 0.3277 | 0.2999 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0026 | 0.0602 | 0.0602 |
Chlamydia trachomatis | deubiquitinase/deneddylase Dub2 | 0.0039 | 0.1384 | 0.5 |
Toxoplasma gondii | beta-tubulin, putative | 0.0181 | 1 | 1 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0903 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0827 | 0.0537 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.007 | 0.3277 | 0.3051 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0181 | 1 | 1 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0602 | 0.0306 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0034 | 0.1056 | 0.0774 |
Schistosoma mansoni | tubulin subunit beta | 0.0181 | 1 | 1 |
Trypanosoma brucei | alpha tubulin | 0.007 | 0.3277 | 0.2999 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0176 | 0.9702 | 0.969 |
Loa Loa (eye worm) | tubulin beta chain | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0602 | 0.0306 |
Plasmodium falciparum | tubulin beta chain | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | tubulin alpha chain | 0.007 | 0.3277 | 0.3064 |
Leishmania major | epsilon tubulin, putative | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0101 | 0.5121 | 0.4957 |
Schistosoma mansoni | nephrin | 0.003 | 0.0837 | 0.0459 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0039 | 0.1384 | 0.0801 |
Trypanosoma brucei | Metacaspase-4 | 0.0027 | 0.0634 | 0.0247 |
Plasmodium vivax | sentrin-specific protease 2, putative | 0.0039 | 0.1384 | 0.1095 |
Trypanosoma brucei | beta tubulin | 0.0181 | 1 | 1 |
Schistosoma mansoni | tubulin subunit epsilon | 0.007 | 0.3277 | 0.2999 |
Plasmodium vivax | tubulin alpha chain, putative | 0.007 | 0.3277 | 0.3051 |
Entamoeba histolytica | tubulin family protein | 0.0181 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.3115 | 0.3115 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0634 | 0.0338 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0034 | 0.1056 | 0.1056 |
Echinococcus granulosus | caspase 2 | 0.0027 | 0.0634 | 0.032 |
Trypanosoma brucei | metacaspase MCA3 | 0.0027 | 0.0634 | 0.0247 |
Trypanosoma cruzi | tubulin gamma chain | 0.007 | 0.3277 | 0.2999 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0039 | 0.1384 | 0.1028 |
Loa Loa (eye worm) | tubulin alpha-3 chain | 0.0031 | 0.0855 | 0.0566 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0181 | 1 | 1 |
Mycobacterium tuberculosis | Cell division protein FtsZ | 0.0031 | 0.0855 | 0.5 |
Trypanosoma brucei | zeta tubulin, putative | 0.0031 | 0.0855 | 0.0477 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0027 | 0.0634 | 0.0634 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0551 | 0.0161 |
Echinococcus granulosus | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | beta-tubulin | 0.0181 | 1 | 1 |
Plasmodium vivax | tubulin epsilon chain, putative | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.004 | 0.1418 | 0.0837 |
Echinococcus granulosus | Immunoglobulin | 0.0026 | 0.0602 | 0.0288 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.5022 | 0.4865 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0903 | 0.0527 |
Echinococcus granulosus | sentrin specific protease 8 | 0.0093 | 0.4685 | 0.4507 |
Leishmania major | SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative | 0.0039 | 0.1384 | 0.1095 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0026 | 0.0602 | 0.0288 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0039 | 0.1384 | 0.1028 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0101 | 0.5121 | 0.4919 |
Brugia malayi | Tubulin alpha chain | 0.007 | 0.3277 | 0.3277 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0039 | 0.1384 | 0.1384 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.003 | 0.0827 | 0.052 |
Echinococcus granulosus | caspase 3 | 0.0074 | 0.3483 | 0.3265 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0101 | 0.5121 | 0.4919 |
Loa Loa (eye worm) | Ulp1 protease | 0.0093 | 0.4685 | 0.4518 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0903 | 0.0903 |
Echinococcus granulosus | beta tubulin | 0.0181 | 1 | 1 |
Trypanosoma brucei | alpha tubulin, putative | 0.004 | 0.1418 | 0.1064 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0039 | 0.1384 | 0.0801 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.007 | 0.3277 | 0.3051 |
Schistosoma mansoni | vesicular amine transporter | 0.0026 | 0.0602 | 0.0215 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0031 | 0.0855 | 0.0236 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0551 | 0.0235 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.007 | 0.3277 | 0.3051 |
Mycobacterium leprae | cell division protein FtsZ | 0.0031 | 0.0855 | 0.5 |
Echinococcus granulosus | sentrin specific protease 1 | 0.0039 | 0.1384 | 0.1095 |
Schistosoma mansoni | tubulin subunit alpha | 0.007 | 0.3277 | 0.2999 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0551 | 0.0235 |
Echinococcus multilocularis | sentrin specific protease 7 | 0.0176 | 0.9702 | 0.9692 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.007 | 0.3277 | 0.3051 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0027 | 0.0634 | 0.032 |
Trypanosoma brucei | tubulin gamma chain | 0.007 | 0.3277 | 0.2999 |
Echinococcus multilocularis | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0039 | 0.1384 | 0.1095 |
Trichomonas vaginalis | sentrin/sumo-specific protease, senp8, putative | 0.0039 | 0.1384 | 0.0801 |
Trypanosoma brucei | metacaspase | 0.0027 | 0.0634 | 0.0247 |
Giardia lamblia | Sentrin specific protease, putative | 0.0039 | 0.1384 | 0.0579 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0027 | 0.0634 | 0.0247 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.5022 | 0.5022 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1384 | 0.1112 |
Schistosoma mansoni | tubulin subunit alpha | 0.007 | 0.3277 | 0.2999 |
Giardia lamblia | Beta tubulin | 0.0181 | 1 | 1 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Trypanosoma cruzi | metacaspase, putative | 0.0027 | 0.0634 | 0.0247 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0855 | 0.0236 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.007 | 0.3277 | 0.2197 |
Onchocerca volvulus | 0.0039 | 0.1384 | 0.9566 | |
Plasmodium vivax | delta tubulin, putative | 0.0031 | 0.0855 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0634 | 0.0338 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0181 | 1 | 1 |
Brugia malayi | Tubulin gamma chain | 0.007 | 0.3277 | 0.3277 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Trypanosoma cruzi | tubulin delta chain | 0.0031 | 0.0855 | 0.0477 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0039 | 0.1384 | 0.0801 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Entamoeba histolytica | tubulin gamma chain | 0.007 | 0.3277 | 0.2197 |
Plasmodium vivax | hypothetical protein, conserved | 0.0027 | 0.0634 | 0.032 |
Giardia lamblia | Beta tubulin | 0.0181 | 1 | 1 |
Brugia malayi | Cell division protein ftsZ | 0.0031 | 0.0855 | 0.0855 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase NSD3 | 0.0033 | 0.1018 | 0.0717 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.007 | 0.3277 | 0.2999 |
Brugia malayi | beta-tubulin, identical | 0.0181 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | tubulin subunit TubB | 0.007 | 0.3277 | 0.3051 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0181 | 1 | 1 |
Trypanosoma cruzi | SUMO1/Ulp2, putative | 0.0039 | 0.1384 | 0.1028 |
Echinococcus multilocularis | tubulin delta chain | 0.0031 | 0.0855 | 0.0548 |
Echinococcus multilocularis | caspase 2 | 0.0027 | 0.0634 | 0.032 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0026 | 0.0602 | 0.0602 |
Brugia malayi | tubulin alpha-2 chain | 0.007 | 0.3277 | 0.3277 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0181 | 1 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Echinococcus multilocularis | hypothetical protein | 0.007 | 0.3277 | 0.3051 |
Trichomonas vaginalis | tubulin, putative | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0181 | 1 | 1 |
Brugia malayi | Tubulin alpha-2 chain | 0.007 | 0.3277 | 0.3277 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | tubulin gamma chain | 0.007 | 0.3277 | 0.3064 |
Trypanosoma brucei | beta tubulin | 0.0181 | 1 | 1 |
Schistosoma mansoni | alpha tubulin | 0.007 | 0.3277 | 0.2999 |
Echinococcus granulosus | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | Ulp1 protease | 0.0039 | 0.1384 | 0.1112 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0026 | 0.0602 | 0.0215 |
Brugia malayi | Tubulin alpha-2 chain | 0.007 | 0.3277 | 0.3277 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.007 | 0.3277 | 0.2822 |
Echinococcus multilocularis | tubulin epsilon chain | 0.007 | 0.3277 | 0.3051 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0031 | 0.0855 | 0.0236 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0027 | 0.0634 | 0.032 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0602 | 0.0306 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.004 | 0.1418 | 0.0837 |
Trypanosoma cruzi | tubulin delta chain | 0.0031 | 0.0855 | 0.0477 |
Plasmodium falciparum | metacaspase-like protein | 0.0027 | 0.0634 | 0.032 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0027 | 0.0634 | 0.032 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0093 | 0.4685 | 0.4326 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.004 | 0.1418 | 0.0837 |
Trypanosoma brucei | tubulin delta chain | 0.0031 | 0.0855 | 0.0477 |
Plasmodium falciparum | metacaspase 1 | 0.0027 | 0.0634 | 0.032 |
Trichomonas vaginalis | tubulin, putative | 0.0031 | 0.0855 | 0.0236 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.5022 | 0.4865 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.004 | 0.1418 | 0.0837 |
Trypanosoma brucei | metacaspase 5, putative | 0.0027 | 0.0634 | 0.0247 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0027 | 0.0634 | 0.0247 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Schistosoma mansoni | alpha tubulin | 0.007 | 0.3277 | 0.2999 |
Schistosoma mansoni | tubulin subunit alpha | 0.0031 | 0.0855 | 0.0477 |
Echinococcus granulosus | twitchin | 0.003 | 0.0837 | 0.053 |
Echinococcus multilocularis | Immunoglobulin | 0.0026 | 0.0602 | 0.0288 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.007 | 0.3277 | 0.2822 |
Entamoeba histolytica | tubulin family protein | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1418 | 0.1147 |
Giardia lamblia | Gamma tubulin | 0.007 | 0.3277 | 0.2648 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0903 | 0.0598 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0039 | 0.1384 | 0.1384 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.004 | 0.1418 | 0.0837 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0903 | 0.0598 |
Echinococcus multilocularis | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Plasmodium falciparum | alpha tubulin 2 | 0.007 | 0.3277 | 0.3051 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0903 | 0.0903 |
Trypanosoma cruzi | metacaspase, putative | 0.0027 | 0.0634 | 0.0247 |
Echinococcus multilocularis | expressed conserved protein | 0.0137 | 0.7314 | 0.7224 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.1384 | 0.0801 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0602 | 0.0306 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0181 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0551 | 0.0235 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.007 | 0.3277 | 0.3064 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.007 | 0.3277 | 0.2822 |
Trichomonas vaginalis | Sentrin-specific protease, putative | 0.0093 | 0.4685 | 0.4326 |
Loa Loa (eye worm) | alpha-tubulin | 0.007 | 0.3277 | 0.3064 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0181 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.004 | 0.1418 | 0.0837 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0027 | 0.0634 | 0.0247 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0602 | 0.0602 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0031 | 0.0855 | 0.0477 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0903 | 0.0616 |
Trypanosoma cruzi | beta tubulin, putative | 0.0181 | 1 | 1 |
Trypanosoma brucei | beta tubulin | 0.0181 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0903 | 0.0527 |
Loa Loa (eye worm) | tubulin alpha chain | 0.007 | 0.3277 | 0.3064 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.007 | 0.3277 | 0.3051 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0181 | 1 | 1 |
Brugia malayi | Tubulin alpha chain | 0.0031 | 0.0855 | 0.0855 |
Giardia lamblia | Alpha-tubulin | 0.007 | 0.3277 | 0.2648 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.007 | 0.3277 | 0.2822 |
Brugia malayi | tubulin alpha chain - mouse | 0.007 | 0.3277 | 0.3277 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0903 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1061 | 0.0779 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0039 | 0.1384 | 0.1095 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.004 | 0.1418 | 0.1147 |
Echinococcus multilocularis | neuroglian | 0.003 | 0.0837 | 0.053 |
Trypanosoma cruzi | metacaspase, putative | 0.0027 | 0.0634 | 0.0247 |
Brugia malayi | Tubulin beta chain | 0.004 | 0.1418 | 0.1418 |
Brugia malayi | serine/threonine protein phosphatase 5 | 0.0022 | 0.0324 | 0.0324 |
Echinococcus multilocularis | tubulin subunit beta | 0.0181 | 1 | 1 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0027 | 0.0634 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0602 | 0.0306 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.007 | 0.3277 | 0.2822 |
Leishmania major | delta tubulin, putative | 0.0031 | 0.0855 | 0.0548 |
Echinococcus multilocularis | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Trypanosoma brucei | alpha tubulin | 0.007 | 0.3277 | 0.2999 |
Schistosoma mansoni | tubulin subunit beta | 0.0031 | 0.0855 | 0.0477 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0031 | 0.0855 | 0.0477 |
Plasmodium vivax | tubulin gamma chain, putative | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | tubulin delta chain | 0.0031 | 0.0855 | 0.0548 |
Echinococcus multilocularis | sentrin specific protease 8 | 0.0093 | 0.4685 | 0.4507 |
Leishmania major | metacaspase, putative | 0.0027 | 0.0634 | 0.032 |
Schistosoma mansoni | tubulin subunit beta | 0.0181 | 1 | 1 |
Leishmania major | alpha tubulin | 0.007 | 0.3277 | 0.3051 |
Plasmodium falciparum | tubulin gamma chain | 0.007 | 0.3277 | 0.3051 |
Echinococcus granulosus | neuroglian | 0.003 | 0.0837 | 0.053 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Trypanosoma brucei | beta tubulin | 0.0181 | 1 | 1 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0039 | 0.1384 | 0.1095 |
Echinococcus granulosus | roundabout 2 | 0.0034 | 0.1061 | 0.0762 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0039 | 0.1384 | 0.0801 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.004 | 0.1418 | 0.1147 |
Echinococcus multilocularis | Immunoglobulin | 0.0026 | 0.0602 | 0.0288 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0093 | 0.4685 | 0.3832 |
Echinococcus granulosus | sentrin specific protease 7 | 0.0176 | 0.9702 | 0.9692 |
Leishmania major | beta tubulin | 0.0181 | 1 | 1 |
Toxoplasma gondii | beta tubulin | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.004 | 0.1418 | 0.1147 |
Brugia malayi | Cell death protein 3 precursor | 0.0027 | 0.0634 | 0.0634 |
Echinococcus granulosus | caspase 8 | 0.0027 | 0.0634 | 0.032 |
Giardia lamblia | Beta tubulin | 0.0181 | 1 | 1 |
Plasmodium vivax | tubulin beta chain, putative | 0.0181 | 1 | 1 |
Trypanosoma brucei | epsilon tubulin | 0.007 | 0.3277 | 0.2999 |
Trypanosoma brucei | epsilon tubulin | 0.007 | 0.3277 | 0.2999 |
Echinococcus granulosus | expressed conserved protein | 0.0137 | 0.7314 | 0.7224 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0031 | 0.0855 | 0.0548 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsZ | 0.0031 | 0.0855 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.5022 | 0.5022 |
Plasmodium vivax | metacaspase 1, putative | 0.0027 | 0.0634 | 0.032 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.007 | 0.3277 | 0.2822 |
Chlamydia trachomatis | deubiquitinase/deneddylase Dub1 | 0.0039 | 0.1384 | 0.5 |
Echinococcus granulosus | tubulin alpha chain | 0.007 | 0.3277 | 0.3051 |
Schistosoma mansoni | tubulin subunit delta | 0.0031 | 0.0855 | 0.0477 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.3115 | 0.2898 |
Echinococcus multilocularis | caspase 3 | 0.0074 | 0.3483 | 0.3265 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.007 | 0.3277 | 0.2197 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.3277 | 0.3064 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.007 | 0.3277 | 0.2822 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0602 | 0.0306 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Kinact (binding) | = 10.7 nM | Inhibition of human cloned CA9 catalytic domain pre-incubated with enzyme for 15 mins by phenol red based CO2 hydration stopped-flow assay | ChEMBL. | 25016228 |
Kinact (binding) | = 12.5 nM | Inhibition of human cloned CA12 catalytic domain pre-incubated with enzyme for 15 mins by phenol red based CO2 hydration stopped-flow assay | ChEMBL. | 25016228 |
Kinact (binding) | = 24.8 nM | Inhibition of human cloned CA2 pre-incubated with enzyme for 15 mins by phenol red based CO2 hydration stopped-flow assay | ChEMBL. | 25016228 |
Kinact (binding) | = 184 nM | Inhibition of human cloned CA1 pre-incubated with enzyme for 15 mins by phenol red based CO2 hydration stopped-flow assay | ChEMBL. | 25016228 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.