Detailed information for compound 921927

Basic information

Technical information
  • TDR Targets ID: 921927
  • Name: N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-(benzot riazol-1-yl)acetamide
  • MW: 385.442 | Formula: C21H15N5OS
  • H donors: 1 H acceptors: 4 LogP: 4.24 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Cn1nnc2c1cccc2)Nc1ccc(cc1)c1nc2c(s1)cccc2
  • InChi: 1S/C21H15N5OS/c27-20(13-26-18-7-3-1-5-16(18)24-25-26)22-15-11-9-14(10-12-15)21-23-17-6-2-4-8-19(17)28-21/h1-12H,13H2,(H,22,27)
  • InChiKey: BBSLAQYFSFJLDI-UHFFFAOYSA-N  

Network

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Synonyms

  • N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-(1-benzotriazolyl)acetamide
  • N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-(benzotriazol-1-yl)ethanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens monoglyceride lipase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase Get druggable targets OG5_127037 All targets in OG5_127037
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE Get druggable targets OG5_127037 All targets in OG5_127037
Trypanosoma brucei gambiense monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Plasmodium vivax PST-A protein Get druggable targets OG5_127037 All targets in OG5_127037
Trypanosoma congolense monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127037 All targets in OG5_127037
Leishmania donovani monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Trypanosoma congolense monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase Get druggable targets OG5_127037 All targets in OG5_127037
Trypanosoma brucei monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis valacyclovir hydrolase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase Get druggable targets OG5_127037 All targets in OG5_127037
Trypanosoma brucei monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_127037 All targets in OG5_127037
Leishmania mexicana monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Mycobacterium tuberculosis Possible lysophospholipase Get druggable targets OG5_127037 All targets in OG5_127037
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127037 All targets in OG5_127037
Trypanosoma brucei gambiense monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Candida albicans similar to YJU3 Get druggable targets OG5_127037 All targets in OG5_127037
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase Get druggable targets OG5_127037 All targets in OG5_127037
Leishmania braziliensis monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Plasmodium falciparum lysophospholipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Plasmodium falciparum esterase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Trypanosoma congolense monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Plasmodium falciparum lysophospholipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Mycobacterium ulcerans lysophospholipase Get druggable targets OG5_127037 All targets in OG5_127037
Candida albicans similar to YJU3 Get druggable targets OG5_127037 All targets in OG5_127037
Plasmodium falciparum lysophospholipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Leishmania major monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Leishmania infantum monoglyceride lipase, putative Get druggable targets OG5_127037 All targets in OG5_127037
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein Get druggable targets OG5_127037 All targets in OG5_127037

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum esterase, putative monoglyceride lipase 303 aa 254 aa 19.7 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.014 0.0697 0.0768
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Echinococcus granulosus neuropeptide s receptor 0.0606 0.3243 0.3243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0021 0.0045 0.0045
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0088 0.0411 0.0411
Onchocerca volvulus Protein ultraspiracle homolog 0.0394 0.2086 0.775
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.014 0.0697 0.1784
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0152 0.0356
Trypanosoma cruzi polyprenyl synthase, putative 0.0029 0.009 0.0083
Echinococcus multilocularis Proteasome subunit alpha type 7 0.014 0.0697 0.0697
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0115
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0029 0.009 0.009
Brugia malayi Ets-domain containing protein 0.0082 0.0376 0.0415
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.014 0.0697 0.0768
Schistosoma mansoni multidrug resistance protein 0.0024 0.0061 0.0145
Schistosoma mansoni growth hormone secretagogue receptor 0.0088 0.0411 0.0984
Trichomonas vaginalis abcb9, putative 0.0024 0.0061 0.0147
Brugia malayi proteasome subunit alpha type 4 0.014 0.0697 0.0776
Schistosoma mansoni cpg binding protein 0.0032 0.0107 0.0256
Plasmodium vivax proteasome subunit beta type-6, putative 0.014 0.0697 0.1784
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0048 0.0045
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0048 0.0048
Echinococcus multilocularis nuclear receptor nhr 48 0.0186 0.0947 0.0947
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0046 0.0183 0.0438
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0152 0.0385
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0088 0.0411 0.0411
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0136 0.0675 0.0744
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0278 0.0686
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0023 0.0025
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0394 0.2086 0.2086
Schistosoma mansoni tyrosine kinase 0.0338 0.1779 0.4259
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0035 0.0123 0.0295
Loa Loa (eye worm) hypothetical protein 0.0075 0.0343 0.0385
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Echinococcus multilocularis jun protein 0.0095 0.0447 0.0447
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0554 0.2961 0.7719
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Brugia malayi Animal haem peroxidase family protein 0.003 0.0092 0.0094
Schistosoma mansoni multidrug resistance protein 0.0024 0.0061 0.0145
Brugia malayi Polyprenyl synthetase family protein 0.0029 0.009 0.0091
Brugia malayi proteasome subunit alpha type 1 0.014 0.0697 0.0776
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0061 0.0147
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0023 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0152 0.0385
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.014 0.0697 0.1714
Loa Loa (eye worm) phospholipase D 0.0022 0.005 0.0055
Trichomonas vaginalis abcb9, putative 0.0024 0.0061 0.0147
Schistosoma mansoni trans-prenyltransferase 0.0029 0.009 0.0214
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0157 0.0157
Mycobacterium leprae Conserved hypothetical protein 0.0057 0.024 0.0402
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Trichomonas vaginalis taga, putative 0.0024 0.0061 0.0147
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.014 0.0697 0.1667
Echinococcus granulosus ecdysone induced protein 78C 0.0394 0.2086 0.2086
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0048 0.0048
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.0145 0.0339
Trichomonas vaginalis glucosylceramidase, putative 0.0291 0.152 0.3961
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0096 0.0238
Onchocerca volvulus 0.0088 0.0411 0.1377
Onchocerca volvulus 0.0046 0.0183 0.0507
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0152 0.0327
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0029 0.009 0.009
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0151 0.0152
Brugia malayi ABC transporter family protein 0.0024 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.015 0.0381
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.014 0.0697 0.0768
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0114
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.0061 0.0067
Onchocerca volvulus 0.0041 0.0152 0.0389
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.015 0.0381
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0013
Schistosoma mansoni lamin 0.0027 0.0076 0.0183
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0051 0.0207 0.0215
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0713 0.3831 1
Echinococcus granulosus insulin receptor 0.011 0.053 0.053
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0152 0.0327
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0019 0.0032 0.0041
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0051 0.0207 0.0215
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.014 0.0697 0.1784
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0029 0.009 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0369
Schistosoma mansoni jun-related protein 0.0077 0.035 0.0838
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.014 0.0697 0.0768
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Leishmania major polyprenyl synthase, putative 0.0029 0.009 0.0083
Leishmania major proteasome beta 3 subunit, putative 0.014 0.0697 0.0768
Onchocerca volvulus 0.0088 0.0411 0.1377
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0115 0.0562 0.1404
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0088 0.0411 0.0463
Loa Loa (eye worm) polyprenyl synthetase 0.0115 0.0562 0.0632
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0095 0.0447 0.0447
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0085 0.0394 0.0814
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0057 0.024 0.0559
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0022 0.0052
Echinococcus multilocularis GPCR, family 2 0.0035 0.0123 0.0123
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Schistosoma mansoni neuropeptide receptor 0.0088 0.0411 0.0984
Toxoplasma gondii cytochrome p450 superfamily protein 0.0057 0.024 0.0587
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.028 0.028
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0115 0.0562 0.0616
Brugia malayi Protein K4 0.0019 0.0032 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Echinococcus granulosus g-protein coupled receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0394 0.2086 0.235
Entamoeba histolytica P-glycoprotein-5 0.0024 0.0061 0.0033
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0017 0.0022 0.0024
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.014 0.0697 0.0768
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0048 0.0115
Echinococcus multilocularis neuropeptide receptor 0.0088 0.0411 0.0411
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0061 0.0033
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0057 0.024 0.0559
Echinococcus granulosus epidermal growth factor receptor 0.0338 0.1779 0.1779
Echinococcus multilocularis transcription factor btf3 0.0039 0.0145 0.0145
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.014 0.0697 0.1714
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0318 0.0761
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0052 0.0052
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0016 0.0016 0.0016
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0046 0.0183 0.0183
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0394 0.2086 0.235
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0123 0.0138
Schistosoma mansoni neuropeptide f receptor 76f 0.0088 0.0411 0.0984
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0151 0.0152
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0057 0.024 0.0559
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0208 0.1069 0.1204
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.028 0.067
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0554 0.2961 0.2961
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0088 0.0411 0.0984
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0061 0.0061
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.014 0.0697 0.0697
Echinococcus multilocularis neuropeptide receptor 0.0088 0.0411 0.0411
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.014 0.0697 0.0768
Schistosoma mansoni hypothetical protein 0.0142 0.0705 0.1688
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0115 0.0562 0.0562
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0061 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0057 0.024 0.0559
Plasmodium falciparum proteasome subunit beta type-6, putative 0.014 0.0697 0.1784
Brugia malayi GnHR receptor homolog 0.0088 0.0411 0.0454
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0394 0.2086 0.2344
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0713 0.3831 0.4307
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0048 0.0115
Echinococcus granulosus proteasome prosome macropain 0.0713 0.3831 0.3831
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0057 0.024 0.0559
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0343 0.1808 0.4652
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0084 0.0391 0.101
Entamoeba histolytica P-glycoprotein-2, putative 0.0024 0.0061 0.0033
Plasmodium vivax proteasome subunit alpha type-1, putative 0.014 0.0697 0.1784
Plasmodium vivax proteasome subunit beta type-3, putative 0.014 0.0697 0.1784
Onchocerca volvulus 0.0088 0.0411 0.1377
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Loa Loa (eye worm) TK protein kinase 0.0046 0.0179 0.0201
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0048 0.0048
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0394 0.2086 0.2086
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0057 0.024 0.0559
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0088 0.0411 0.0984
Brugia malayi SRC-1 0.0054 0.0225 0.0244
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.014 0.0697 0.0768
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.014 0.0697 0.1667
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0152 0.0327
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0399 0.2112 0.2112
Onchocerca volvulus 0.0088 0.0411 0.1377
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0046 0.0183 0.0438
Loa Loa (eye worm) hypothetical protein 0.0076 0.0347 0.039
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Schistosoma mansoni rab6-interacting 0.0022 0.0052 0.0124
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0394 0.2086 0.235
Brugia malayi Furin-like cysteine rich region family protein 0.0338 0.1779 0.1998
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0105 0.0101
Schistosoma mansoni phospholipase D 0.0116 0.0563 0.1349
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0152 0.017
Brugia malayi nuclear hormone receptor 0.0394 0.2086 0.2344
Schistosoma mansoni thyroid hormone receptor 0.0536 0.2861 0.6847
Echinococcus multilocularis GA binding protein alpha chain 0.0082 0.0376 0.0376
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.014 0.0697 0.1784
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0061 0.0061
Entamoeba histolytica phospholipase D, putative 0.0116 0.0563 0.1362
Giardia lamblia 20S proteasome alpha subunit 3 0.014 0.0697 0.1784
Plasmodium falciparum proteasome subunit beta type-7, putative 0.014 0.0697 0.1784
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0059 0.0113
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.014 0.0697 0.1809
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.014 0.0697 0.1667
Brugia malayi Animal haem peroxidase family protein 0.003 0.0092 0.0094
Trypanosoma brucei proteasome beta 7 subunit 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.0208 0.1069 0.1204
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0186 0.0947 0.0947
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Schistosoma mansoni cytochrome P450 0.0057 0.024 0.0574
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Brugia malayi Nuclear hormone receptor-like 1 0.0208 0.1069 0.1196
Brugia malayi Serotonin receptor 0.0606 0.3243 0.365
Toxoplasma gondii hypothetical protein 0.0046 0.0183 0.0437
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0183 0.0437
Plasmodium vivax amine transporter, putative 0.0046 0.0183 0.0437
Echinococcus granulosus FTZ F1 alpha 0.0394 0.2086 0.2086
Toxoplasma gondii proteasome beta subunit 0.014 0.0697 0.1784
Brugia malayi hypothetical protein 0.0041 0.0152 0.0161
Trypanosoma cruzi cytochrome P450, putative 0.0085 0.0394 0.0427
Leishmania major proteasome beta-1 subunit, putative 0.014 0.0697 0.0768
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Mycobacterium tuberculosis Conserved protein 0.0041 0.0152 0.0327
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0057 0.024 0.0402
Onchocerca volvulus 0.0041 0.0152 0.0389
Echinococcus multilocularis NCK adaptor protein 0.0017 0.0022 0.0022
Echinococcus granulosus phospholipase D1 0.0116 0.0563 0.0563
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0145 0.0146
Plasmodium falciparum lysophospholipase, putative 0.0084 0.0391 0.0982
Echinococcus multilocularis tyrosine protein kinase Abl 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0088 0.0411 0.1377
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0057 0.024 0.0402
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Brugia malayi Fli-1 protein 0.0248 0.1284 0.1439
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0088 0.0411 0.0411
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0021 0.0021
Loa Loa (eye worm) proteasome subunit alpha type 3 0.014 0.0697 0.0784
Onchocerca volvulus Glucosylceramidase homolog 0.0191 0.0973 0.3516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0064 0.028 0.0314
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0057 0.024 0.0253
Brugia malayi ecdysteroid receptor 0.0394 0.2086 0.2344
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0051 0.0207 0.0215
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0024
Onchocerca volvulus Peroxidase homolog 0.003 0.0092 0.0161
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Mycobacterium tuberculosis Possible lysophospholipase 0.0084 0.0391 0.0955
Echinococcus multilocularis G protein coupled receptor 139 0.0088 0.0411 0.0411
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0046 0.0183 0.0183
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0342 0.18 0.2028
Plasmodium vivax proteasome subunit beta type-5, putative 0.0713 0.3831 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0046 0.0183 0.0183
Trypanosoma cruzi sterol C-24 reductase, putative 0.0053 0.0222 0.0232
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.014 0.0697 0.0697
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0152 0.0167
Echinococcus multilocularis fmrfamide receptor 0.0088 0.0411 0.0411
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0088 0.0411 0.1377
Echinococcus multilocularis lamin 0.0027 0.0076 0.0076
Plasmodium vivax multidrug resistance protein 1, putative 0.0024 0.0061 0.0117
Echinococcus multilocularis growth factor receptor bound protein 2 0.0017 0.0022 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0186 0.0947 0.1059
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0973 0.2532
Echinococcus granulosus subfamily T1A non peptidase ue 0.014 0.0697 0.0697
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0029 0.009 0.0192
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0197
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0152 0.0327
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0505 0.2693 0.2693
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0186 0.0947 0.1059
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0343 0.1808 0.4327
Mycobacterium leprae Probable lipase LipE 0.0041 0.0152 0.0167
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0713 0.3831 0.4307
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0017
Plasmodium falciparum lysophospholipase, putative 0.0084 0.0391 0.0982
Schistosoma mansoni nuclear hormone receptor 0.0394 0.2086 0.4992
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Trypanosoma cruzi C-14 sterol reductase, putative 0.0053 0.0222 0.0232
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0048 0.0045
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0394 0.2086 0.2086
Onchocerca volvulus 0.0027 0.0076 0.0102
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0048 0.0053
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Brugia malayi Tyrosine-protein kinase abl-1 0.0021 0.0045 0.0041
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Trypanosoma brucei C-14 sterol reductase, putative 0.0053 0.0222 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.015 0.0381
Brugia malayi Melatonin receptor type 1A 0.0088 0.0411 0.0454
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0671 0.3597 0.3597
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.014 0.0697 0.1809
Echinococcus multilocularis neuropeptide FF receptor 2 0.0088 0.0411 0.0411
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.014 0.0697 0.1714
Giardia lamblia Proteasome subunit beta type 9 precursor 0.014 0.0697 0.1784
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0713 0.3831 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0057 0.024 0.0559
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0152 0.0363
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0016 0.0016 0.0009
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.014 0.0697 0.0768
Brugia malayi Proteasome A-type and B-type family protein 0.014 0.0697 0.0776
Loa Loa (eye worm) cytochrome P450 family protein 0.01 0.0475 0.0534
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0225 0.0225
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Echinococcus multilocularis Proteasome subunit alpha type 7 0.014 0.0697 0.0697
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0084 0.0391 0.101
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0394 0.2086 0.4992
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) hypothetical protein 0.0208 0.1069 0.1204
Echinococcus multilocularis microtubule associated protein 2 0.0777 0.4178 0.4178
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0008
Schistosoma mansoni lipoxygenase 0.0133 0.0656 0.1571
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0088 0.0411 0.0984
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.014 0.0697 0.1784
Brugia malayi Serotonin receptor 0.0088 0.0411 0.0454
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0394 0.2086 0.2344
Brugia malayi hypothetical protein 0.0208 0.1069 0.1196
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0207 0.0232
Loa Loa (eye worm) DR-78 0.0186 0.0947 0.1067
Trypanosoma brucei cardiolipin synthetase 0.004 0.0151 0.0152
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0399 0.2112 0.2373
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0023 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0136 0.0344
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0272 0.1419 0.1591
Onchocerca volvulus 0.0088 0.0411 0.1377
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0061 0.0061
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0136 0.0344
Echinococcus granulosus growth factor receptor bound protein 2 0.0017 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Brugia malayi Proteasome A-type and B-type family protein 0.014 0.0697 0.0776
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0205
Plasmodium falciparum proteasome subunit beta type-3, putative 0.014 0.0697 0.1784
Echinococcus granulosus transcription factor btf3 0.0039 0.0145 0.0145
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0554 0.2961 0.77
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.014 0.0697 0.0768
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.014 0.0697 0.1667
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.014 0.0697 0.1714
Echinococcus granulosus Proteasome subunit alpha beta 0.014 0.0697 0.0697
Echinococcus granulosus dnaJ subfamily B 0.0461 0.2448 0.2448
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.014 0.0697 0.1784
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0046 0.0183 0.0183
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.014 0.0697 0.0768
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0061 0.0061
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0088 0.0411 0.0411
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0061 0.0061
Echinococcus multilocularis lamin b receptor 0.0053 0.0222 0.0222
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0152 0.0153
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0027 0.0013
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0152 0.0152
Onchocerca volvulus Chorion peroxidase homolog 0.003 0.0092 0.0161
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.014 0.0697 0.0697
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0343 0.1808 0.4327
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0048 0.0048
Brugia malayi hypothetical protein 0.0022 0.0048 0.0045
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0208 0.1069 0.1069
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1636 0.8872 1
Loa Loa (eye worm) solute carrier family 6 member 4 0.0272 0.1419 0.1598
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0186 0.0947 0.0947
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0437
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0391 0.101
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.014 0.0697 0.1784
Echinococcus multilocularis serotonin transporter 0.0272 0.1419 0.1419
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0048 0.0115
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0441 0.2344 0.2641
Brugia malayi isocitrate dehydrogenase 0.0018 0.0027 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0152 0.0363
Brugia malayi CXXC zinc finger family protein 0.0032 0.0107 0.0111
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0029 0.009 0.0163
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.014 0.0697 0.1667
Giardia lamblia 20S proteasome alpha subunit 2 0.014 0.0697 0.1784
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0136 0.0675 0.0675
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0343 0.1808 0.1808
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0027 0.003
Schistosoma mansoni adenoreceptor 0.0088 0.0411 0.0984
Leishmania major proteasome beta 2 subunit, putative 0.014 0.0697 0.0768
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.014 0.0697 0.0768
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0029 0.009 0.0109
Onchocerca volvulus 0.046 0.2447 0.9125
Brugia malayi Dopamine receptor protein 1 0.0088 0.0411 0.0454
Loa Loa (eye worm) serotonin transporter b 0.0272 0.1419 0.1598
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0136 0.0344
Schistosoma mansoni microtubule-associated protein tau 0.0777 0.4178 1
Brugia malayi proteasome subunit alpha type 2 0.014 0.0697 0.0776
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus granulosus RUN 0.0022 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0053
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0019 0.0032 0.0017
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0115 0.0562 0.0616
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0029 0.009 0.0109
Brugia malayi Calcitonin receptor-like protein seb-1 0.0112 0.054 0.0599
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Brugia malayi Nuclear hormone receptor-like 1 0.0394 0.2086 0.2344
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0048 0.0115
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0016 0.0016 0.0016
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.014 0.0697 0.1784
Echinococcus granulosus 7tm_1 domain containing protein 0.0088 0.0411 0.0411
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0394 0.2086 0.2086
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0133 0.0656 0.0656
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.014 0.0697 0.1784
Trypanosoma cruzi cytochrome P450, putative 0.0085 0.0394 0.0427
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.046 0.2447 0.2745
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0186 0.0947 0.1067
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0048 0.0048
Brugia malayi nuclear receptor NHR-88 0.0186 0.0947 0.1059
Loa Loa (eye worm) blistered cuticle protein 3 0.003 0.0092 0.0103
Schistosoma mansoni rab6-interacting 0.0022 0.0052 0.0124
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0297 0.1554 0.1554
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0138
Brugia malayi proteasome subunit beta type 3 0.014 0.0697 0.0776
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0394 0.0443
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0029 0.009 0.0163
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0057 0.024 0.0559
Echinococcus multilocularis multidrug resistance protein 1 0.0017 0.0021 0.0021
Brugia malayi follicle stimulating hormone receptor 0.0088 0.0411 0.0454
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Schistosoma mansoni histamine h1 receptor 0.0088 0.0411 0.0984
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0051 0.0207 0.0215
Schistosoma mansoni tyrosine kinase 0.0054 0.0225 0.0538
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0394 0.2086 0.2086
Echinococcus multilocularis proteasome subunit beta type 6 0.014 0.0697 0.0697
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0057 0.024 0.0559
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0017
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0052 0.0052
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0046 0.0183 0.0183
Brugia malayi G protein-coupled receptor 0.0088 0.0411 0.0454
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.046 0.2447 0.2745
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0157 0.0176
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0016 0.0016 0.0009
Loa Loa (eye worm) polyprenyl synthetase 0.0029 0.009 0.01
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0291 0.152 0.1705
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0394 0.2086 0.2344
Echinococcus granulosus Nuclear hormone receptor HR96 0.0186 0.0947 0.0947
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) proteasome subunit beta type 1 0.0554 0.2961 0.3336
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.0145 0.0146
Echinococcus multilocularis neuropeptide s receptor 0.0606 0.3243 0.3243
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0394 0.2086 0.2344
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.103 0.2679
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0115 0.0562 0.1344
Entamoeba histolytica Ran family GTPase 0.0024 0.0059 0.0029
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0061 0.0061
Brugia malayi Pre-SET motif family protein 0.0064 0.028 0.0306
Schistosoma mansoni hypothetical protein 0.0088 0.0411 0.0984
Trypanosoma cruzi sterol C-24 reductase, putative 0.0053 0.0222 0.0232
Loa Loa (eye worm) TK protein kinase 0.0037 0.0133 0.0149
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0048 0.0048
Onchocerca volvulus 0.003 0.0092 0.0161
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0029 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0205
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0046 0.0183 0.0438
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0053
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Loa Loa (eye worm) animal heme peroxidase 0.003 0.0092 0.0103
Schistosoma mansoni smdr2 0.0024 0.0061 0.0145
Schistosoma mansoni cpg binding protein 0.0034 0.0117 0.028
Loa Loa (eye worm) proteasome subunit beta type 2 0.0343 0.1808 0.2037
Schistosoma mansoni nuclear hormone receptor 0.0186 0.0947 0.2267
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Echinococcus multilocularis fmrfamide receptor 0.0088 0.0411 0.0411
Trypanosoma brucei ATP-dependent protease subunit HslV 0.014 0.0697 0.0768
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.0274
Brugia malayi tailless protein 0.0186 0.0947 0.1059
Onchocerca volvulus 0.0088 0.0411 0.1377
Echinococcus multilocularis tyrosine protein kinase HCK 0.0037 0.0133 0.0133
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0263 0.0263
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0027 0.0021
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.014 0.0697 0.0768
Brugia malayi Proteasome A-type and B-type family protein 0.0713 0.3831 0.4312
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0072 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0291 0.152 0.3961
Trichomonas vaginalis esterase, putative 0.0041 0.0152 0.0385
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0057 0.024 0.0402
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0291 0.152 0.1713
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.014 0.0697 0.0768
Trypanosoma cruzi cardiolipin synthetase, putative 0.004 0.0151 0.0152
Brugia malayi G protein-coupled receptor F59B2.13 0.0088 0.0411 0.0454
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0076 0.0077
Schistosoma mansoni lamin 0.0027 0.0076 0.0183
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0052 0.0052
Brugia malayi ORL1-like opioid receptor 0.0088 0.0411 0.0454
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0057 0.024 0.0402
Loa Loa (eye worm) animal heme peroxidase 0.003 0.0092 0.0103
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0046 0.0183 0.0438
Onchocerca volvulus 0.0088 0.0411 0.1377
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0207 0.0224
Mycobacterium ulcerans hypothetical protein 0.0084 0.0391 0.0805
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0029 0.009 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0196
Echinococcus granulosus peptide allatostatin:somatostatin 0.0088 0.0411 0.0411
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0085
Echinococcus granulosus G protein coupled receptor 139 0.0088 0.0411 0.0411
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0021 0.0045 0.0108
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0027 0.0013
Echinococcus granulosus cpg binding protein 0.0034 0.0117 0.0117
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0136 0.0675 0.0744
Loa Loa (eye worm) norepinephrine transporter 0.0272 0.1419 0.1598
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0191 0.0973 0.233
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.0145 0.0257
Plasmodium vivax proteasome subunit alpha type-2, putative 0.014 0.0697 0.1784
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0027 0.003
Trypanosoma brucei proteasome beta 2 subunit, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0143
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.014 0.0697 0.0768
Echinococcus granulosus allatostatin A receptor 0.0088 0.0411 0.0411
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0029 0.009 0.0083
Loa Loa (eye worm) hypothetical protein 0.0225 0.1161 0.1308
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0225 0.0225
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0059 0.0113
Schistosoma mansoni retinoic acid receptor RXR 0.0505 0.2693 0.6444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0196
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0052 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0057 0.024 0.0559
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0152 0.0327
Brugia malayi conserved hypotetical protein 0.0186 0.0947 0.1059
Brugia malayi Cytochrome P450 family protein 0.0085 0.0394 0.0435
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Schistosoma mansoni biogenic amine receptor 0.0088 0.0411 0.0984
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0208 0.1069 0.1069
Entamoeba histolytica hypothetical protein 0.0039 0.0145 0.0257
Schistosoma mansoni tyrosine kinase 0.0179 0.0906 0.2169
Echinococcus granulosus neuropeptides capa receptor 0.0088 0.0411 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0048
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0115 0.0562 0.0616
Trypanosoma cruzi Emopamil binding protein, putative 0.046 0.2447 0.2745
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) TYRA-2 protein 0.0088 0.0411 0.0463
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0088 0.0411 0.0411
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.0274
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Echinococcus granulosus phospholipase D 0.0102 0.049 0.049
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0186 0.0947 0.2267
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0016 0.0031
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0029 0.009 0.0083
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0112 0.054 0.0599
Schistosoma mansoni sodium/chloride dependent transporter 0.0046 0.0183 0.0438
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0022 0.0052 0.0057
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0072 0.0177
Echinococcus multilocularis orexin receptor type 2 0.0088 0.0411 0.0411
Schistosoma mansoni hypothetical protein 0.0088 0.0411 0.0984
Onchocerca volvulus 0.0502 0.2677 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0186 0.0947 0.2267
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0205
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0088 0.0411 0.0984
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Brugia malayi Peroxidasin 0.003 0.0092 0.0094
Schistosoma mansoni sodium/chloride dependent transporter 0.0046 0.0183 0.0438
Plasmodium vivax cardiolipin synthetase, putative 0.0019 0.0032 0.0041
Brugia malayi hypothetical protein 0.003 0.0092 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0394 0.2086 0.235
Entamoeba histolytica hypothetical protein 0.0026 0.0072 0.0063
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0019 0.0032 0.0041
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Trypanosoma brucei proteasome beta 6 subunit 0.0554 0.2961 0.3325
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0019 0.0032 0.0041
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0059 0.0049
Echinococcus granulosus cytochrome P450 2K1 0.0057 0.024 0.024
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0016 0.0016 0.0009
Loa Loa (eye worm) hypothetical protein 0.0519 0.2766 0.3117
Loa Loa (eye worm) hypothetical protein 0.0272 0.1419 0.1598
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Trypanosoma brucei monoglyceride lipase, putative 0.0084 0.0391 0.0423
Echinococcus granulosus proteasome subunit alpha type 2 0.014 0.0697 0.0697
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.014 0.0697 0.1667
Mycobacterium ulcerans proteasome PrcA 0.014 0.0697 0.1623
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.014 0.0697 0.1714
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.014 0.0697 0.1714
Brugia malayi latrophilin 2 splice variant baaae 0.0076 0.0347 0.0382
Brugia malayi Animal haem peroxidase family protein 0.003 0.0092 0.0094
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0016 0.0016 0.0016
Brugia malayi Cytochrome P450 family protein 0.01 0.0475 0.0526
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Toxoplasma gondii ABC1 family protein 0.0041 0.0152 0.0356
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.014 0.0697 0.1667
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.028 0.028
Leishmania major proteasome beta 5 subunit, putative 0.0713 0.3831 0.4307
Schistosoma mansoni peroxidasin 0.003 0.0092 0.022
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1842 1 1
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0027 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0079 0.0196
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0186 0.0947 0.0947
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.014 0.0697 0.0768
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0021 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0022 0.0052 0.0057
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0399 0.2112 0.5054
Echinococcus granulosus biogenic amine 5HT receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) proteasome subunit beta type 3 0.014 0.0697 0.0784
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0057 0.024 0.0253
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0394 0.2086 0.2086
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0152 0.0167
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0225 0.0225
Giardia lamblia Proteasome subunit beta type 2 0.0343 0.1808 0.4697
Echinococcus multilocularis Proteasome subunit alpha type 7 0.014 0.0697 0.0697
Leishmania major proteasome alpha 1 subunit, putative 0.014 0.0697 0.0768
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0027 0.0066
Echinococcus granulosus serotonin transporter 0.0272 0.1419 0.1419
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0061 0.0147
Mycobacterium ulcerans lipase LipD 0.0041 0.0152 0.0167
Echinococcus granulosus neuropeptides capa receptor 0.0088 0.0411 0.0411
Trichomonas vaginalis abcb9, putative 0.0024 0.0061 0.0147
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0051 0.0207 0.0215
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.014 0.0697 0.1784
Loa Loa (eye worm) hypothetical protein 0.1636 0.8872 1
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0048 0.0048
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.014 0.0697 0.1714
Echinococcus multilocularis RUN 0.0022 0.0052 0.0052
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0394 0.2086 0.2086
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0394 0.2086 0.2344
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.0554 0.296 0.3336
Brugia malayi sulfakinin receptor protein 0.0088 0.0411 0.0454
Brugia malayi hypothetical protein 0.0186 0.0947 0.1059
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0084 0.0391 0.101
Schistosoma mansoni polycystin 1-related 0.0022 0.0052 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0079 0.0196
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.014 0.0697 0.0784
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0343 0.1808 0.4697
Onchocerca volvulus 0.0032 0.0107 0.0218
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0713 0.3831 1
Trichomonas vaginalis glucosylceramidase, putative 0.0201 0.103 0.2679
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0057 0.024 0.0559
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0048 0.0048
Brugia malayi cytochrome P450 0.0057 0.024 0.0261
Schistosoma mansoni thyroid hormone receptor 0.0536 0.2861 0.6847
Plasmodium falciparum amino acid transporter, putative 0.0046 0.0183 0.0437
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0272 0.1419 0.3395
Echinococcus granulosus proteasome subunit beta type 6 0.014 0.0697 0.0697
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0046 0.0183 0.0438
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0394 0.2086 0.235
Trypanosoma brucei proteasome beta 3 subunit, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0029 0.009 0.0192
Schistosoma mansoni nuclear receptor 0.0186 0.0947 0.2267
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0394 0.2086 0.2344
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0157 0.0157
Loa Loa (eye worm) G-protein coupled receptor 0.0088 0.0411 0.0463
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0088 0.0411 0.0984
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.011 0.053 0.053
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0016 0.0016 0.0031
Toxoplasma gondii NAC domain-containing protein 0.0039 0.0145 0.0339
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0057 0.024 0.0402
Echinococcus granulosus lamin 0.0027 0.0076 0.0076
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.0411 0.0984
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0088 0.0411 0.0454
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0029 0.009 0.3828
Onchocerca volvulus 0.0024 0.0061 0.0042
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0208 0.1069 0.2558
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Loa Loa (eye worm) cytochrome P450 0.0057 0.024 0.027
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0399 0.2112 0.2112
Schistosoma mansoni hypothetical protein 0.0077 0.035 0.0838
Schistosoma mansoni hypothetical protein 0.0041 0.0152 0.0363
Brugia malayi Sex muscle abnormal protein 5 0.0017 0.0022 0.0015
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0048 0.0045
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0136 0.0675 0.0675
Onchocerca volvulus 0.0046 0.0183 0.0507
Trypanosoma cruzi polyprenyl synthase, putative 0.0029 0.009 0.0083
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus granulosus tyrosine protein kinase HCK 0.0037 0.0133 0.0133
Onchocerca volvulus Peroxidase homolog 0.003 0.0092 0.0161
Echinococcus multilocularis dro:myosuppressin receptor 0.0088 0.0411 0.0411
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0052 0.0052
Brugia malayi nuclear receptor NHR-67 0.0186 0.0947 0.1059
Echinococcus multilocularis tyrosine protein kinase Blk 0.0046 0.0179 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0152 0.0153
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0225 0.0225
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0048 0.0048
Toxoplasma gondii hypothetical protein 0.0046 0.0183 0.0437
Brugia malayi Doublecortin family protein 0.0022 0.0052 0.0049
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0061 0.0147
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.014 0.0697 0.0768
Trypanosoma brucei C-8 sterol isomerase, putative 0.1636 0.8872 1
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Onchocerca volvulus 0.003 0.0092 0.0161
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0207 0.0529
Leishmania major cytochrome p450-like protein 0.0057 0.024 0.0253
Leishmania major monoglyceride lipase, putative 0.0084 0.0391 0.0423
Brugia malayi Cytochrome P450 family protein 0.0057 0.024 0.0261
Echinococcus multilocularis proteasome subunit alpha type 2 0.014 0.0697 0.0697
Echinococcus multilocularis FTZ F1 alpha 0.0394 0.2086 0.2086
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0554 0.2961 0.3325
Schistosoma mansoni tyrosine kinase 0.0054 0.0225 0.0538
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.014 0.0697 0.0768
Plasmodium vivax proteasome subunit alpha type-7, putative 0.014 0.0697 0.1784
Onchocerca volvulus Bile acid receptor homolog 0.0394 0.2086 0.775
Echinococcus multilocularis sodium and chloride dependent glycine 0.0046 0.0183 0.0183
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0084 0.0391 0.101
Plasmodium vivax proteasome subunit beta type-4, putative 0.014 0.0697 0.1784
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Schistosoma mansoni adapter molecule crk 0.0017 0.0022 0.0052
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0088 0.0411 0.0984
Toxoplasma gondii proteasome subunit 0.014 0.0697 0.1784
Schistosoma mansoni ran 0.0024 0.0059 0.0142
Brugia malayi 20S proteasome alpha5 subunit 0.014 0.0697 0.0776
Schistosoma mansoni opsin-like receptor 0.0088 0.0411 0.0984
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Trypanosoma cruzi Emopamil binding protein, putative 0.046 0.2447 0.2745
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0096 0.0238
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0052 0.0052
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0051 0.0207 0.0419
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0048 0.0114
Onchocerca volvulus Peroxidasin homolog 0.003 0.0092 0.0161
Brugia malayi hypothetical protein 0.0022 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.0105 0.0118
Echinococcus multilocularis g protein coupled receptor 0.0088 0.0411 0.0411
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0048 0.0053
Echinococcus multilocularis somatostatin receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0017
Loa Loa (eye worm) beta-lactamase 0.0041 0.0152 0.017
Onchocerca volvulus 0.0088 0.0411 0.1377
Schistosoma mansoni tyrosine kinase 0.0179 0.0906 0.2169
Echinococcus granulosus g protein coupled receptor 0.0088 0.0411 0.0411
Brugia malayi ecdysone receptor 0.0186 0.0947 0.1059
Trypanosoma cruzi monoglyceride lipase, putative 0.0084 0.0391 0.0423
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.014 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.017
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0076 0.0085
Schistosoma mansoni nuclear receptor nhr-48 0.0186 0.0947 0.2267
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0048 0.0048
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0061 0.0061
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0152 0.0385
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0052 0.0052
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0186 0.0947 0.0947
Brugia malayi Protein kinase domain containing protein 0.011 0.053 0.0588
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0088 0.0411 0.0984
Schistosoma mansoni biogenic amine receptor 0.0088 0.0411 0.0984
Schistosoma mansoni ran 0.0024 0.0059 0.0142
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0133 0.0656 0.0656
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0057 0.024 0.0402
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0057 0.024 0.0402
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Schistosoma mansoni tyrosine kinase 0.0021 0.0045 0.0108
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0022 0.0052
Schistosoma mansoni tyrosine kinase 0.011 0.053 0.1268
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0016 0.0016 0.0016
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0136 0.0344
Brugia malayi Polyprenyl synthetase family protein 0.0115 0.0562 0.0624
Echinococcus granulosus 7TM GPCR rhodopsin 0.0088 0.0411 0.0411
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0554 0.2961 0.3325
Echinococcus granulosus neuropeptide Y receptor 0.0088 0.0411 0.0411
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0048 0.0115
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0123 0.0123
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0022 0.0015
Loa Loa (eye worm) hypothetical protein 0.0272 0.1419 0.1598
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0394 0.2086 0.2086
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.0061 0.0117
Brugia malayi hypothetical protein 0.0019 0.0032 0.0026
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0059 0.0059
Echinococcus granulosus biogenic amine 5HT receptor 0.0225 0.1161 0.1161
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0057 0.024 0.0559
Schistosoma mansoni alpha-1 adrenergic receptor 0.0088 0.0411 0.0984
Echinococcus multilocularis proteasome (prosome, macropain) 0.0713 0.3831 0.3831
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.014 0.0697 0.0768
Leishmania major importin beta-1 subunit, putative 0.0026 0.0072 0.0063
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0152 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0048
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0059 0.0049
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0123 0.0123
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0059 0.0113
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.014 0.0697 0.0697
Echinococcus granulosus tachykinin peptides receptor 99D 0.0088 0.0411 0.0411
Echinococcus multilocularis G-protein coupled receptor, putative 0.0088 0.0411 0.0411
Schistosoma mansoni transcription factor btf3 0.0039 0.0145 0.0348
Loa Loa (eye worm) hypothetical protein 0.0208 0.1069 0.1204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Brugia malayi RNA, U transporter 1 0.0091 0.0428 0.0474
Leishmania major GTP-binding protein, putative 0.0024 0.0059 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0178 0.0426
Plasmodium falciparum lysophospholipase, putative 0.0084 0.0391 0.0982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0196
Giardia lamblia Proteasome subunit beta type 1 0.0554 0.2961 0.7719
Echinococcus granulosus fmrfamide receptor 0.0088 0.0411 0.0411
Echinococcus granulosus thyroid hormone receptor alpha 0.0186 0.0947 0.0947
Loa Loa (eye worm) hypothetical protein 0.0208 0.1069 0.1204
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0061 0.0061
Schistosoma mansoni Lamin B receptor (ERG24) 0.0053 0.0222 0.053
Onchocerca volvulus 0.0088 0.0411 0.1377
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0059 0.0049
Brugia malayi intermediate filament protein 0.0027 0.0076 0.0077
Echinococcus multilocularis sex peptide receptor 0.0088 0.0411 0.0411
Mycobacterium ulcerans beta-lactamase 0.0041 0.0152 0.0167
Echinococcus granulosus NCK adaptor protein 0.0017 0.0022 0.0022
Brugia malayi Phospholipase d protein 1 0.0116 0.0563 0.0626
Plasmodium vivax PST-A protein 0.0084 0.0391 0.0982
Echinococcus multilocularis geminin 0.0191 0.0973 0.0973
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0207 0.0529
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.014 0.0697 0.1714
Schistosoma mansoni intermediate filament proteins 0.0027 0.0076 0.0183
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.028 0.0691
Echinococcus multilocularis Proteasome, subunit alpha beta 0.014 0.0697 0.0697
Leishmania major proteasome alpha 3 subunit, putative 0.014 0.0697 0.0768
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0061 0.0147
Entamoeba histolytica P-glyco protein 6, putative 0.0024 0.0061 0.0033
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.014 0.0697 0.1667
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0088 0.0411 0.0411
Schistosoma mansoni hypothetical protein 0.0035 0.0123 0.0295
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.014 0.0697 0.1784
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0088 0.0411 0.0411
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0156 0.0156
Echinococcus multilocularis serotonin receptor 0.0225 0.1161 0.1161
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0115 0.0562 0.143
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0029 0.009 0.0109
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0205
Schistosoma mansoni neuropeptide receptor 0.0088 0.0411 0.0984
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0048 0.0115
Giardia lamblia Proteasome subunit beta type 7 precursor 0.014 0.0697 0.1784
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.014 0.0697 0.1714
Schistosoma mansoni biogenic amine receptor 0.0088 0.0411 0.0984
Loa Loa (eye worm) melatonin receptor type 1A 0.0088 0.0411 0.0463
Echinococcus multilocularis epidermal growth factor receptor 0.0338 0.1779 0.1779
Loa Loa (eye worm) hypothetical protein 0.0097 0.0462 0.052
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0369
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.014 0.0697 0.1667
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Brugia malayi neuropeptide F receptor 0.0088 0.0411 0.0454
Brugia malayi Animal haem peroxidase family protein 0.003 0.0092 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.028 0.067
Plasmodium falciparum multidrug resistance protein 1 0.0024 0.0061 0.0117
Echinococcus multilocularis tyrosine protein kinase Srms 0.0046 0.0179 0.0179
Echinococcus multilocularis neuropeptide Y receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0205
Brugia malayi nuclear receptor RXR 0.0186 0.0947 0.1059
Echinococcus multilocularis peroxidasin 0.003 0.0092 0.0092
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0061 0.0147
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0052 0.0057
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0061 0.0147
Brugia malayi photoreceptor-specific nuclear receptor 0.0394 0.2086 0.2344
Giardia lamblia 20S proteasome alpha subunit 4 0.014 0.0697 0.1784
Echinococcus multilocularis epidermal growth factor receptor 0.0183 0.093 0.093
Echinococcus granulosus 20S proteasome subunit alpha 6 0.014 0.0697 0.0697
Schistosoma mansoni tyrosine kinase 0.0021 0.0045 0.0108
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0186 0.0947 0.0947
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.014 0.0697 0.1667
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0016 0.0031
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0059 0.0059
Mycobacterium ulcerans proteasome PrcB 0.0713 0.3831 1
Leishmania major proteasome alpha 2 subunit, putative 0.014 0.0697 0.0768
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.014 0.0697 0.0768
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0061 0.0147
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.017
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0115 0.0562 0.143
Echinococcus multilocularis serotonin receptor 0.0225 0.1161 0.1161
Schistosoma mansoni hypothetical protein 0.0076 0.0347 0.083
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0554 0.2961 0.7726
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0023 0.0008
Plasmodium falciparum esterase, putative 0.0084 0.0391 0.0982
Leishmania major farnesyl pyrophosphate synthase 0.0115 0.0562 0.0616
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0017
Brugia malayi nuclear hormone receptor 0.0186 0.0947 0.1059
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0016 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0088 0.0411 0.0984
Toxoplasma gondii phospholipase D active site domain-containing protein 0.004 0.0151 0.0354
Trypanosoma brucei Emopamil binding protein, putative 0.046 0.2447 0.2745
Echinococcus multilocularis 0.0057 0.024 0.024
Leishmania major sterol C-24 reductase, putative 0.0053 0.0222 0.0232
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0021 0.0021
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0029 0.009 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0291 0.152 0.3961
Schistosoma mansoni sodium-dependent amino acid transporter 0.0046 0.0183 0.0438
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Giardia lamblia 20S proteasome alpha subunit 7 0.014 0.0697 0.1784
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.014 0.0697 0.0768
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.017
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0013
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.014 0.0697 0.0768
Toxoplasma gondii proteasome subunit alpha1, putative 0.014 0.0697 0.1784
Echinococcus granulosus nuclear receptor nhr 48 0.0186 0.0947 0.0947
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0186 0.0947 0.0947
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0136 0.0675 0.1727
Schistosoma mansoni glutathione synthetase 0.0029 0.009 0.0214
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0061 0.0147
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.014 0.0697 0.1809
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0343 0.1808 0.2023
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0084 0.0391 0.0906
Echinococcus granulosus sodium and chloride dependent glycine 0.0046 0.0183 0.0183
Onchocerca volvulus 0.0088 0.0411 0.1377
Plasmodium vivax SET domain protein, putative 0.0064 0.028 0.0691
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0017 0.0022 0.0052
Brugia malayi hypothetical protein 0.0022 0.0048 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0094 0.0234
Brugia malayi orphan nuclear receptor NR2E1 0.0186 0.0947 0.1059
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0554 0.2961 0.7085
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0022 0.005 0.0038
Loa Loa (eye worm) G-protein coupled receptor 0.0088 0.0411 0.0463
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0061 0.0147
Mycobacterium tuberculosis Conserved protein 0.0041 0.0152 0.0327
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0343 0.1808 0.4713
Brugia malayi Dopamine receptor protein 2 0.0088 0.0411 0.0454
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.014 0.0697 0.0784
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0029 0.009 0.009
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0029 0.009 0.009
Onchocerca volvulus 0.0027 0.0076 0.0102
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Schistosoma mansoni hypothetical protein 0.0461 0.2448 0.5859
Schistosoma mansoni opsin-like receptor 0.0088 0.0411 0.0984
Leishmania major basic transcription factor 3a, putative 0.0039 0.0145 0.0146
Schistosoma mansoni amine GPCR 0.0088 0.0411 0.0984
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) proteasome subunit alpha type 1 0.014 0.0697 0.0784
Brugia malayi G-protein coupled receptor 0.0088 0.0411 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0207 0.0529
Giardia lamblia 20S proteasome alpha subunit 6 0.014 0.0697 0.1784
Schistosoma mansoni hypothetical protein 0.0035 0.0123 0.0295
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0343 0.1808 0.4713
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0016 0.0016 0.0016
Echinococcus granulosus hypothetical protein 0.0865 0.4659 0.4659
Leishmania major proteasome beta 7 subunit, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0088 0.0411 0.0463
Schistosoma mansoni hypothetical protein 0.0191 0.0973 0.233
Loa Loa (eye worm) hypothetical protein 0.0024 0.0061 0.0067
Echinococcus granulosus serotonin receptor 0.0088 0.0411 0.0411
Onchocerca volvulus 0.003 0.0092 0.0161
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.014 0.0697 0.1759
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0554 0.2961 0.2961
Echinococcus multilocularis neuropeptides capa receptor 0.0088 0.0411 0.0411
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0024 0.0061 0.005
Plasmodium falciparum transporter, putative 0.0046 0.0183 0.0437
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0088 0.0411 0.0454
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0061 0.0147
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0016 0.0016 0.0017
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Echinococcus granulosus epidermal growth factor receptor 0.0183 0.093 0.093
Trypanosoma brucei cytochrome P450, putative 0.0085 0.0394 0.0427
Plasmodium vivax proteasome subunit alpha type-3, putative 0.014 0.0697 0.1784
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0394 0.2086 0.4992
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0029 0.009 0.0091
Brugia malayi protein-tyrosine kinase 0.0046 0.0179 0.0193
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0205
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0076 0.0085
Brugia malayi nuclear receptor NHR-88 0.0394 0.2086 0.2344
Brugia malayi putative neuropeptide receptor 0.0088 0.0411 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0048
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0142 0.036
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Echinococcus multilocularis neuropeptide receptor A26 0.0606 0.3243 0.3243
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0394 0.2086 0.2344
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0136 0.0675 0.0744
Trypanosoma cruzi C-14 sterol reductase, putative 0.0053 0.0222 0.0232
Echinococcus granulosus neuropeptide FF receptor 2 0.0088 0.0411 0.0411
Leishmania major C-8 sterol isomerase-like protein 0.1636 0.8872 1
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.014 0.0697 0.1714
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0197
Giardia lamblia 20S proteasome alpha subunit 1 0.014 0.0697 0.1784
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0152 0.0167
Echinococcus granulosus sex peptide receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0046 0.0183 0.0438
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.017
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus granulosus importin subunit beta 1 0.0032 0.0105 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0291 0.152 0.3961
Loa Loa (eye worm) animal heme peroxidase 0.003 0.0092 0.0103
Loa Loa (eye worm) neuropeptide F receptor 0.0088 0.0411 0.0463
Schistosoma mansoni neuropeptide receptor 0.0088 0.0411 0.0984
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0029 0.009 0.0083
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0046 0.0183 0.0438
Giardia lamblia 20S proteasome alpha subunit 5 0.014 0.0697 0.1784
Schistosoma mansoni hypothetical protein 0.0035 0.0123 0.0295
Schistosoma mansoni neuropeptide receptor 0.0088 0.0411 0.0984
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Echinococcus granulosus Nuclear hormone receptor HR96 0.0186 0.0947 0.0947
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0016 0.0016 0.0009
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0136 0.0314
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0115 0.0562 0.1456
Loa Loa (eye worm) hypothetical protein 0.0075 0.0343 0.0385
Echinococcus granulosus orexin receptor type 2 0.0088 0.0411 0.0411
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0016 0.0016 0.0031
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0115 0.0562 0.143
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0973 0.2532
Leishmania major proteasome beta 2 subunit, putative 0.0343 0.1808 0.2023
Echinococcus granulosus proteasome subunit alpha type 6 0.014 0.0697 0.0697
Brugia malayi Dopamine receptor 0.0088 0.0411 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0048
Schistosoma mansoni amine GPCR 0.0461 0.245 0.5865
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0024 0.0061 0.0087
Brugia malayi Importin beta-1 subunit 0.0032 0.0105 0.0109
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0088 0.0411 0.0454
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0115 0.0562 0.0562
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Echinococcus granulosus GA binding protein alpha chain 0.0082 0.0376 0.0376
Mycobacterium leprae putative cytochrome p450 0.0057 0.024 0.0402
Toxoplasma gondii proteasome subunit beta type, putative 0.0713 0.3831 1
Echinococcus granulosus insulin growth factor 1 receptor beta 0.011 0.053 0.053
Echinococcus granulosus snurportin 1 0.0342 0.18 0.18
Brugia malayi neuropeptide F receptor 0.0088 0.0411 0.0454
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0016 0.0016 0.0016
Schistosoma mansoni loxhd1 0.0022 0.0052 0.0124
Echinococcus multilocularis phospholipase D1 0.0116 0.0563 0.0563
Brugia malayi RE15519p 0.0088 0.0411 0.0454
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0057 0.024 0.0253
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.014 0.0697 0.0784
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0713 0.3831 0.4307
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0152 0.0153
Brugia malayi beta-lactamase family protein 0.0041 0.0152 0.0162
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0142 0.0705 0.0705
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0123 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0114
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0072 0.0063
Brugia malayi Animal haem peroxidase family protein 0.003 0.0092 0.0094
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0061 0.0061
Treponema pallidum sodium- and chloride- dependent transporter 0.0272 0.1419 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.017
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0057 0.024 0.0402
Trypanosoma brucei proteasome beta-1 subunit, putative 0.014 0.0697 0.0768
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0114
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0061 0.0061
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0554 0.2961 0.7719
Echinococcus multilocularis lamin dm0 0.0027 0.0076 0.0076
Schistosoma mansoni tyrosine kinase 0.011 0.053 0.1268
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.014 0.0697 0.1784
Echinococcus multilocularis expressed protein 0.042 0.2228 0.2228
Trypanosoma brucei monoglyceride lipase, putative 0.0084 0.0391 0.0423
Loa Loa (eye worm) hypothetical protein 0.0554 0.296 0.3336
Mycobacterium tuberculosis Conserved protein 0.0041 0.0152 0.0327
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0259 0.1346 0.3468
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0186 0.0947 0.3416
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0027 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0394 0.2086 0.235
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Brugia malayi Proteasome subunit alpha type 1 0.014 0.0697 0.0776
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.008 0.0196
Brugia malayi hypothetical protein 0.0074 0.0336 0.037
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0048 0.0048
Leishmania major p-glycoprotein 0.0024 0.0061 0.005
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0088 0.0411 0.0984
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0061 0.0061
Echinococcus multilocularis phospholipase d3 0.0022 0.005 0.005
Plasmodium vivax proteasome subunit beta type-1, putative 0.0554 0.2961 0.7719
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0183 0.093 0.093
Entamoeba histolytica P-glycoprotein-1 0.0024 0.0061 0.0033
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Brugia malayi Phospholipase D. Active site motif family protein 0.0022 0.005 0.0046
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0016 0.0016 0.0016
Echinococcus granulosus proteasome subunit beta t family 0.014 0.0697 0.0697
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0088 0.0411 0.0411
Onchocerca volvulus 0.0022 0.0052 0.0007
Schistosoma mansoni tyrosine kinase 0.0183 0.093 0.2225
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0016 0.0016 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0136 0.0675 0.1727
Echinococcus multilocularis ecdysone induced protein 78C 0.0394 0.2086 0.2086
Schistosoma mansoni multidrug resistance protein 0.0024 0.0061 0.0145
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0225 0.0225
Leishmania major solanesyl-diphosphate synthase, putative 0.0029 0.009 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0973 0.2532
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Brugia malayi nuclear hormone receptor family member nhr-6 0.0186 0.0947 0.1059
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0208 0.1069 0.1204
Echinococcus granulosus sodium and chloride dependent glycine 0.0046 0.0183 0.0183
Onchocerca volvulus 0.0088 0.0411 0.1377
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0048 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0136 0.0344
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0046 0.0183 0.0183
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0057 0.024 0.0559
Echinococcus multilocularis insulin receptor 0.011 0.053 0.053
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0225 0.0225
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0061 0.0147
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Brugia malayi PXA domain containing protein 0.0027 0.0076 0.0076
Onchocerca volvulus 0.0088 0.0411 0.1377
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.014 0.0697 0.1667
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0115 0.0562 0.1262
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0048 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0016 0.0031
Brugia malayi proteasome subunit beta type 2 0.0343 0.1808 0.203
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.014 0.0697 1
Plasmodium vivax proteasome subunit beta type-2, putative 0.0343 0.1808 0.4697
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0048 0.0045
Schistosoma mansoni hypothetical protein 0.0022 0.0052 0.0124
Plasmodium falciparum proteasome subunit beta type-5 0.0713 0.3831 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0057 0.024 0.0559
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0057 0.024 0.0559
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0057 0.024 0.0402
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0115 0.0562 0.1262
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0343 0.1808 0.2023
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0061 0.0147
Schistosoma mansoni importin beta-1 0.0032 0.0105 0.0252
Trichomonas vaginalis set domain proteins, putative 0.0502 0.2677 0.6985
Entamoeba histolytica proteasome subunit beta type 3, putative 0.014 0.0697 0.1714
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0713 0.3831 1
Schistosoma mansoni sorting nexin 0.0013 0.0003 0.0007
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.014 0.0697 0.1667
Leishmania major proteasome alpha 7 subunit, putative 0.014 0.0697 0.0768
Echinococcus multilocularis dnaJ subfamily B 0.0461 0.2448 0.2448
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0115
Echinococcus multilocularis musashi 0.0027 0.0076 0.0076
Echinococcus granulosus tyrosine protein kinase Lyn 0.0054 0.0225 0.0225
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Echinococcus granulosus c src tyrosine kinase 0.0021 0.0045 0.0045
Leishmania major proteasome alpha 7 subunit, putative 0.014 0.0697 0.0768
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0394 0.2086 0.4992
Loa Loa (eye worm) hypothetical protein 0.0112 0.054 0.0608
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.014 0.0697 0.0768
Schistosoma mansoni biogenic amine (5HT) receptor 0.0225 0.1161 0.2779
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0048 0.0045
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0048 0.0048
Brugia malayi hypothetical protein 0.0046 0.0183 0.0197
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Echinococcus granulosus lamin dm0 0.0027 0.0076 0.0076
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0048 0.0115
Brugia malayi proteasome subunit alpha type 6 0.014 0.0697 0.0776
Echinococcus granulosus g protein coupled receptor 0.0088 0.0411 0.0411
Schistosoma mansoni peroxidasin 0.003 0.0092 0.022
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0136 0.0675 0.1727
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0197
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.014 0.0697 0.0768
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0394 0.2086 0.2344
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0186 0.0947 0.3416
Echinococcus granulosus dro:myosuppressin receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) nuclear receptor NHR-67 0.0186 0.0947 0.1067
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.014 0.0697 0.0768
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0157 0.0168
Trichomonas vaginalis ran, putative 0.0024 0.0059 0.0143
Schistosoma mansoni nck2/grb4 0.0017 0.0022 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0394 0.2086 0.235
Echinococcus granulosus phospholipase d3 0.0022 0.005 0.005
Mycobacterium ulcerans hypothetical protein 0.0041 0.0152 0.0167
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0115 0.0562 0.1456
Leishmania major cardiolipin synthetase, putative 0.0019 0.0032 0.0017
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.014 0.0697 0.0784
Trypanosoma cruzi cardiolipin synthetase, putative 0.004 0.0151 0.0152
Brugia malayi Steroid receptor seven-up type 2 0.0394 0.2086 0.2344
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0973 0.2532
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.014 0.0697 0.0768
Onchocerca volvulus 0.0088 0.0411 0.1377
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0022 0.0015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0394 0.2086 0.775
Schistosoma mansoni tyrosine kinase 0.0179 0.0906 0.2169
Onchocerca volvulus 0.0394 0.2086 0.775
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0115
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0072 0.0177
Loa Loa (eye worm) hypothetical protein 0.0097 0.0462 0.052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0136 0.0344
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0057 0.024 0.0559
Echinococcus granulosus neuropeptide receptor A26 0.0606 0.3243 0.3243
Onchocerca volvulus 0.0272 0.1419 0.5211
Loa Loa (eye worm) hypothetical protein 0.0357 0.1883 0.2122
Schistosoma mansoni RAR-like nuclear receptor 0.0394 0.2086 0.4992
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.015 0.0381
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0057 0.024 0.0253
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.014 0.0697 0.1784
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0136 0.0675 0.0744
Echinococcus multilocularis neuropeptides capa receptor 0.0088 0.0411 0.0411
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.014 0.0697 0.0784
Onchocerca volvulus 0.0088 0.0411 0.1377
Onchocerca volvulus 0.0088 0.0411 0.1377
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0057 0.024 0.0559
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.028 0.028
Echinococcus granulosus proteasome subunit beta type 7 0.014 0.0697 0.0697
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0051 0.0207 0.0207
Onchocerca volvulus 0.0186 0.0947 0.3416
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0225 0.0225
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0057 0.024 0.0402
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0123 0.0129
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0061 0.0061
Echinococcus multilocularis sodium and chloride dependent glycine 0.0046 0.0183 0.0183
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0084 0.0391 0.0906
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) SRC-1 0.0054 0.0225 0.0252
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0059 0.0059
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0713 0.3831 0.9168
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0369
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0394 0.2086 0.2344
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Echinococcus multilocularis g-protein coupled receptor 0.0088 0.0411 0.0411
Brugia malayi hypothetical protein 0.0208 0.1069 0.1196
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.014 0.0697 0.1809
Echinococcus multilocularis c src tyrosine kinase 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0041 0.0152 0.0389
Echinococcus granulosus somatostatin receptor 0.0088 0.0411 0.0411
Brugia malayi multidrug resistance protein 3 0.0024 0.0061 0.0059
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.014 0.0697 0.0768
Trypanosoma cruzi 20S proteasome subunit 0.0343 0.1808 0.2023
Schistosoma mansoni hypothetical protein 0.0342 0.18 0.4308
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.015 0.0381
Echinococcus granulosus lamin b receptor 0.0053 0.0222 0.0222
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0225 0.0225
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0029 0.009 0.0163
Leishmania major proteasome alpha 1 subunit, putative 0.014 0.0697 0.0768
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0394 0.2086 0.2086
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0057 0.024 0.0402
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0973 0.2532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0048
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0208 0.1069 0.2558
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0205
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0061 0.0117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Loa Loa (eye worm) TK/EGFR protein kinase 0.0338 0.1779 0.2005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0136 0.0344
Echinococcus granulosus alpha 1A adrenergic receptor 0.0088 0.0411 0.0411
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0152 0.0385
Echinococcus granulosus microtubule associated protein 2 0.0777 0.4178 0.4178
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0394 0.2086 0.2086
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Leishmania major C-14 sterol reductase, putative 0.0053 0.0222 0.0232
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0394 0.2086 0.4992
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0046 0.0183 0.0438
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0023 0.0008
Onchocerca volvulus Peroxidasin homolog 0.003 0.0092 0.0161
Entamoeba histolytica P-glycoprotein 5, putative 0.0024 0.0061 0.0033
Plasmodium falciparum proteasome subunit beta type-4 0.014 0.0697 0.1784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0166 0.0423
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0023 0.0023
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0152 0.0327
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0027 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0029 0.009 0.01
Echinococcus multilocularis subfamily T1A non peptidase ue 0.014 0.0697 0.0697
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0105 0.0101
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0437
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0088 0.0411 0.0463
Echinococcus granulosus intermediate filament protein 0.0027 0.0076 0.0076
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.014 0.0697 0.0768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.011 0.0275
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0029 0.009 0.0214
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.0274
Echinococcus granulosus tyrosine protein kinase Blk 0.0046 0.0179 0.0179
Leishmania major hypothetical protein, conserved 0.046 0.2447 0.2745
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0112 0.054 0.0608
Schistosoma mansoni amine GPCR 0.0088 0.0411 0.0984
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.0411 0.0984
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0061 0.0051
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0394 0.2086 0.2086
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0046 0.0179 0.0179
Schistosoma mansoni tyrosine kinase 0.0183 0.093 0.2225
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0052 0.0093
Onchocerca volvulus 0.0186 0.0947 0.3416
Plasmodium vivax proteasome subunit alpha type-6, putative 0.014 0.0697 0.1784
Brugia malayi hypothetical protein 0.0022 0.0052 0.0049
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0554 0.2961 0.3325
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0225 0.0225
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0156 0.0156
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0027 0.0027
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.046 0.2447 0.2745
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0115
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0713 0.3831 0.4317
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.014 0.0697 0.1784
Echinococcus multilocularis proteasome subunit beta type 7 0.014 0.0697 0.0697
Brugia malayi steroid hormone receptor 0.0394 0.2086 0.2344
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0061 0.0147
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0225 0.0225
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0088 0.0411 0.0984
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0088 0.0411 0.0984
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0084 0.0391 0.101
Echinococcus granulosus tyrosine kinase 0.0046 0.0179 0.0179
Schistosoma mansoni opsin-like receptor 0.0088 0.0411 0.0984
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0035
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Brugia malayi nuclear receptor RXR 0.0208 0.1069 0.1196
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0394 0.2086 0.2086
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.014 0.0697 0.1714
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0057 0.024 0.0402
Echinococcus multilocularis cpg binding protein 0.0034 0.0117 0.0117
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.014 0.0697 0.1667
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0061 0.0147
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0394 0.2086 0.4992
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0009 0.0009
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0048 0.0053
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1636 0.8872 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0059 0.0113
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0145 0.0146
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Trypanosoma brucei cardiolipin synthetase, putative 0.004 0.0151 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0114
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0084 0.0391 0.101
Brugia malayi proteasome subunit alpha type 3 0.014 0.0697 0.0776
Brugia malayi Blistered cuticle protein 3 0.003 0.0092 0.0094
Loa Loa (eye worm) nuclear hormone receptor 0.0186 0.0947 0.1067
Echinococcus granulosus g protein coupled receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) neuropeptide F receptor 0.0088 0.0411 0.0463
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.0411 0.0984
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0088 0.0411 0.0411
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0088 0.0411 0.0411
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0084 0.0391 0.0805
Plasmodium vivax proteasome subunit beta type-7, putative 0.014 0.0697 0.1784
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0343 0.1808 0.4697
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0114
Toxoplasma gondii proteasome subunit alpha type, putative 0.014 0.0697 0.1784
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0051 0.0207 0.0495
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0394 0.2086 0.2344
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0051 0.0207 0.0215
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0057 0.024 0.0402
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0225 0.0225
Brugia malayi G-protein coupled receptor 0.0088 0.0411 0.0454
Giardia lamblia Proteasome subunit beta type 4 precursor 0.014 0.0697 0.1784
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0023 0.0059 0.0059
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Schistosoma mansoni hypothetical protein 0.0057 0.024 0.0574
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0057 0.024 0.0559
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.014 0.0697 0.1714
Echinococcus multilocularis allatostatin A receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) ICD-1 protein 0.0039 0.0145 0.0163
Brugia malayi beta-lactamase family protein 0.0041 0.0152 0.0162
Leishmania major cytochrome p450-like protein 0.0057 0.024 0.0253
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0048 0.0048
Echinococcus granulosus neuropeptide Y receptor 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0024 0.0061 0.0067
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.014 0.0697 0.1667
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.014 0.0697 0.0768
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0115
Trypanosoma brucei proteasome alpha 7 subunit 0.014 0.0697 0.0768
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0391 0.101
Echinococcus multilocularis neuropeptide Y receptor 0.0088 0.0411 0.0411
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.028 0.067
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0048 0.0048
Schistosoma mansoni neuropeptide F-like receptor 0.0088 0.0411 0.0984
Loa Loa (eye worm) animal heme peroxidase 0.003 0.0092 0.0103
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0008
Plasmodium vivax importin-beta 2, putative 0.0032 0.0105 0.0234
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0123 0.0123
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0225 0.0225
Brugia malayi Ets-domain containing protein 0.0082 0.0376 0.0415
Brugia malayi PXA domain containing protein 0.0027 0.0076 0.0076
Brugia malayi hypothetical protein 0.0186 0.0947 0.1059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0116 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0114
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0016 0.0016 0.0016
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0027 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.014 0.0697 0.0768
Loa Loa (eye worm) PDE1B protein 0.0399 0.2112 0.238
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.014 0.0697 0.1714
Loa Loa (eye worm) CYP4Cod1 0.0085 0.0394 0.0443
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0411 0.0984
Giardia lamblia Farnesyl diphosphate synthase 0.0115 0.0562 0.143
Echinococcus multilocularis g protein coupled receptor 0.0088 0.0411 0.0411
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.014 0.0697 0.1809
Giardia lamblia GTOR 0.0051 0.0207 0.05
Brugia malayi Pre-SET motif family protein 0.0441 0.2344 0.2635
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0082
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0016 0.0016 0.0039
Loa Loa (eye worm) PXA domain-containing protein 0.0027 0.0076 0.0084
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0029 0.009 0.0871
Echinococcus granulosus GPCR family 2 0.0035 0.0123 0.0123
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0057 0.024 0.0402
Plasmodium vivax proteasome subunit alpha type-5, putative 0.014 0.0697 0.1784
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0051 0.0207 0.0207
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0142 0.036
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0088 0.0411 0.0463
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0115 0.0562 0.1456
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0394 0.2086 0.4992
Loa Loa (eye worm) proteasome subunit alpha type 6 0.014 0.0697 0.0784
Trichomonas vaginalis glucosylceramidase, putative 0.0291 0.152 0.3961
Brugia malayi beta-lactamase 0.0041 0.0152 0.0162
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0437
Onchocerca volvulus Neuropeptide F receptor homolog 0.0088 0.0411 0.1377
Brugia malayi Nuclear hormone receptor E75 0.0186 0.0947 0.1059
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0046 0.0183 0.0205
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0031 0.0039
Entamoeba histolytica protein kinase, putative 0.0037 0.0133 0.0224
Brugia malayi larval opioid receptor 0.0088 0.0411 0.0454
Onchocerca volvulus Dual oxidase homolog 0.003 0.0092 0.0161
Echinococcus granulosus neuropeptide receptor 0.0088 0.0411 0.0411
Onchocerca volvulus Notchless protein homolog 0.014 0.0697 0.2463
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0179 0.0179
Schistosoma mansoni nuclear receptor 0.0186 0.0947 0.2267
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0152 0.0162
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0017 0.0021 0.0044
Loa Loa (eye worm) fli-1 protein 0.0248 0.1284 0.1446
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0152 0.0327
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0225 0.0225
Mycobacterium ulcerans lysophospholipase 0.0084 0.0391 0.0805
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0343 0.1808 0.1808
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0088 0.0411 0.0411
Schistosoma mansoni amine GPCR 0.0088 0.0411 0.0984
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0057 0.024 0.0402
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0048 0.0048
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0013
Brugia malayi hypothetical protein 0.0137 0.068 0.0757
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0178 0.0426
Schistosoma mansoni ets-related 0.0248 0.1284 0.3072
Echinococcus granulosus geminin 0.0191 0.0973 0.0973
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0394 0.0443
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0046 0.0183 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0186 0.0947 0.1059
Onchocerca volvulus 0.0022 0.0052 0.0007
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.014 0.0697 0.1784
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0105 0.0234
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.014 0.0697 0.1667
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0057 0.024 0.0402
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0088 0.0411 0.0411
Brugia malayi proteasome subunit beta type 1 0.0554 0.2961 0.333
Echinococcus multilocularis 0.0104 0.0499 0.0499
Schistosoma mansoni cpg binding protein 0.0034 0.0117 0.028
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0046 0.0183 0.0197
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Plasmodium falciparum importin beta, putative 0.0032 0.0105 0.0234
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0048 0.0115
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0045 0.0033
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0103
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0016 0.0016 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0057 0.024 0.0559
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0059 0.0066
Plasmodium vivax proteasome subunit alpha type-4, putative 0.014 0.0697 0.1784
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0096 0.0238
Leishmania major cytochrome p450-like protein 0.0085 0.0394 0.0427
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0001 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0208 0.1069 0.1196
Brugia malayi hypothetical protein 0.0088 0.0411 0.0454
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0152 0.0152
Brugia malayi Cytochrome P450 family protein 0.0085 0.0394 0.0435
Echinococcus granulosus expressed protein 0.042 0.2228 0.2228
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0016 0.0016 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0291 0.152 0.3961
Loa Loa (eye worm) hypothetical protein 0.007 0.0311 0.035
Echinococcus granulosus jun protein 0.0095 0.0447 0.0447
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0061 0.0061
Loa Loa (eye worm) steroid hormone receptor 0.0394 0.2086 0.235
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0152 0.0152
Echinococcus multilocularis g protein coupled receptor 0.0088 0.0411 0.0411
Brugia malayi Proteasome A-type and B-type family protein 0.014 0.0697 0.0776
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0029 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0183 0.0205
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Echinococcus granulosus Proteasome subunit alpha type 7 0.014 0.0697 0.0697
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0057 0.024 0.0402
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0019 0.0032 0.0076
Onchocerca volvulus 0.0074 0.0336 0.109
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0061 0.0147
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0017 0.0022 0.0024
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0051 0.0207 0.0419
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0107 0.012
Schistosoma mansoni sodium/chloride dependent transporter 0.0272 0.1419 0.3395
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0088 0.0411 0.0411
Brugia malayi beta-NAC-like protein 0.0039 0.0145 0.0154
Echinococcus multilocularis phospholipase D 0.0102 0.049 0.049
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0061 0.0147
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0057 0.024 0.0253
Onchocerca volvulus 0.0064 0.028 0.0876
Echinococcus granulosus peroxidasin 0.003 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0272 0.1419 0.1598
Toxoplasma gondii peptidase, T1 family protein 0.014 0.0697 0.1784
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0713 0.3831 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0065
Loa Loa (eye worm) proteasome subunit alpha type 2 0.014 0.0697 0.0784
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0973 0.2532
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0088 0.0411 0.0454
Echinococcus multilocularis thyroid hormone receptor alpha 0.0536 0.2861 0.2861
Schistosoma mansoni gabp alpha 0.0082 0.0376 0.09
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.017
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0671 0.3597 0.3597
Entamoeba histolytica P-glycoprotein-2 0.0024 0.0061 0.0033
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0057 0.024 0.0559
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0394 0.2086 0.2344
Schistosoma mansoni lipoxygenase 0.0093 0.0438 0.1048
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0046 0.0183 0.0183
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0973 0.2532
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0152 0.0385
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.0055
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0394 0.2086 0.2344
Echinococcus granulosus neuropeptide receptor 0.0088 0.0411 0.0411
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0016 0.0016 0.0016
Loa Loa (eye worm) TK/INSR protein kinase 0.011 0.053 0.0597
Schistosoma mansoni amine GPCR 0.0088 0.0411 0.0984
Brugia malayi putative neuropeptide receptor NPR1 0.0088 0.0411 0.0454
Loa Loa (eye worm) hypothetical protein 0.0225 0.1161 0.1308
Entamoeba histolytica phospholipase D, putative 0.0116 0.0563 0.1362
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0057 0.024 0.0402
Loa Loa (eye worm) PAS-3 protein 0.014 0.0697 0.0784
Brugia malayi Tachykinin-like peptides receptor 99D 0.0088 0.0411 0.0454
Echinococcus multilocularis proteasome subunit alpha type 6 0.014 0.0697 0.0697
Schistosoma mansoni nuclear hormone receptor 0.0186 0.0947 0.2267
Loa Loa (eye worm) hypothetical protein 0.0186 0.0947 0.1067
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0142 0.0705 0.0705
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0057 0.024 0.0402
Leishmania major hypothetical protein, conserved 0.0041 0.0152 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0394 0.2086 0.2344
Giardia lamblia Proteasome subunit beta type 3 0.014 0.0697 0.1784
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0016 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0836 0.4501 0.5072
Brugia malayi AKH receptor 0.0088 0.0411 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0094 0.0234
Loa Loa (eye worm) hypothetical protein 0.0092 0.0433 0.0487
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.014 0.0697 0.1714
Schistosoma mansoni coup transcription factor 0.0394 0.2086 0.4992
Loa Loa (eye worm) hypothetical protein 0.0088 0.0411 0.0463
Loa Loa (eye worm) hypothetical protein 0.0394 0.2086 0.235
Schistosoma mansoni myosin xvIII 0.0088 0.0411 0.0984
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0088 0.0411 0.0454
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0095 0.0447 0.0447
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0057 0.024 0.0402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0079 0.0196
Schistosoma mansoni biogenic amine (5HT) receptor 0.0088 0.0411 0.0984
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0016 0.0016 0.0031
Brugia malayi Proteasome subunit alpha type 7-1 0.014 0.0697 0.0776
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0151 0.0152
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.0061 0.0067
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0016 0.0031
Brugia malayi Phospholipase D. Active site motif family protein 0.004 0.0151 0.0161
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0059 0.0057
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0048 0.0045
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0082 0.0376 0.0423
Schistosoma mansoni zinc finger protein 0.0186 0.0947 0.2267
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.014 0.0697 0.1714
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.014 0.0697 0.1623
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.014 0.0697 0.0697
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0088 0.0411 0.0984
Onchocerca volvulus 0.0088 0.0411 0.1377
Toxoplasma gondii heat shock protein hslv, putative 0.014 0.0697 0.1784
Echinococcus multilocularis conserved hypothetical protein 0.0777 0.4178 0.4178
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0016 0.0039
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.0145 0.0339
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0084 0.0094
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0411 0.0411
Echinococcus multilocularis snurportin 1 0.0342 0.18 0.18
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0048 0.0048
Onchocerca volvulus 0.0046 0.0183 0.0507
Schistosoma mansoni steroid hormone receptor ad4bp 0.0394 0.2086 0.4992
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0008
Brugia malayi bZIP transcription factor family protein 0.0095 0.0447 0.0495
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0061 0.0147
Echinococcus granulosus tm gpcr rhodopsin 0.0088 0.0411 0.0411
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.028 0.067
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0024 0.0061 0.1921
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0088 0.0411 0.0411
Schistosoma mansoni neuropeptide F-like receptor 0.0088 0.0411 0.0984
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0088 0.0411 0.0463
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0097 0.0462 0.1094
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0061 0.0147

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 14.28 % Inhibition of human MAGL assessed as residual enzyme activity at 100 uM using 4-Nitrophenylacetate substrate incubated for 15 mins ChEMBL. 25011912
Activity (binding) = 15.09 % Inhibition of human MAGL assessed as residual enzyme activity at 10 uM using 4-Nitrophenylacetate substrate incubated for 15 mins ChEMBL. 25011912
Activity (binding) = 17.1 % Inhibition of human MAGL assessed as residual enzyme activity at 1 uM using 4-Nitrophenylacetate substrate incubated for 15 mins ChEMBL. 25011912
Activity (binding) = 21.15 % Inhibition of human MAGL assessed as residual enzyme activity at 100 nM using 4-Nitrophenylacetate substrate incubated for 15 mins ChEMBL. 25011912
Activity (binding) = 51.23 % Inhibition of human MAGL assessed as residual enzyme activity at 10 nM using 4-Nitrophenylacetate substrate incubated for 15 mins ChEMBL. 25011912
Activity (binding) = 81.4 % Inhibition of human MAGL assessed as residual enzyme activity at 1 nM using 4-Nitrophenylacetate substrate incubated for 15 mins ChEMBL. 25011912
Fa (ADMET) = 100 % Oral absorption in human ChEMBL. 25011912
IC50 (binding) = 10 nM Inhibition of human MAGL using 4-Nitrophenylacetate substrate incubated for 15 mins ChEMBL. 25011912

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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