Detailed information for compound 922798

Basic information

Technical information
  • TDR Targets ID: 922798
  • Name: 1-(4-nitrophenyl)-2-[(8-oxo-1-azabicyclo[2.2. 2]octan-7-yl)methyl]butane-1,3-dione
  • MW: 344.362 | Formula: C18H20N2O5
  • H donors: 0 H acceptors: 5 LogP: 1.83 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C(C(=O)C)CC1N2CCC(C1=O)CC2)c1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C18H20N2O5/c1-11(21)15(10-16-18(23)13-6-8-19(16)9-7-13)17(22)12-2-4-14(5-3-12)20(24)25/h2-5,13,15-16H,6-10H2,1H3
  • InChiKey: OYCSKQKYVYWFLJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-nitrophenyl)-2-[(3-oxoquinuclidin-2-yl)methyl]butane-1,3-dione
  • 1-(4-nitrophenyl)-2-[(3-oxo-2-quinuclidinyl)methyl]butane-1,3-dione
  • 2-[(3-ketoquinuclidin-2-yl)methyl]-1-(4-nitrophenyl)butane-1,3-dione

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi G-protein coupled receptor 0.0105 0.3802 0.3974
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0105 0.3802 0.3824
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0105 0.3802 0.3802
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0846 0.085
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.2716 0.5188
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0041 0.0846 0.0846
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Schistosoma mansoni tyrosine kinase 0.0091 0.316 0.3178
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0846 0.085
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.2764 0.2889
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis neuropeptide FF receptor 2 0.0105 0.3802 0.3802
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0105 0.3802 0.3824
Trichomonas vaginalis STE family protein kinase 0.0083 0.2783 0.5544
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0761 0.0796
Loa Loa (eye worm) TK protein kinase 0.0068 0.208 0.208
Echinococcus multilocularis c src tyrosine kinase 0.0028 0.0241 0.0241
Echinococcus multilocularis neuropeptide Y receptor 0.0105 0.3802 0.3802
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0846 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.2764 0.2764
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.2716 0.5188
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.2764 0.2764
Brugia malayi steroid hormone receptor 0.0083 0.2764 0.2889
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0105 0.3802 0.3824
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0105 0.3802 0.3824
Schistosoma mansoni tyrosine kinase 0.009 0.3107 0.3124
Onchocerca volvulus 0.0105 0.3802 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0079 0.26 0.26
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0077 0.2512 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0105 0.3802 0.3802
Echinococcus granulosus somatostatin receptor 0.0105 0.3802 0.3802
Brugia malayi Serotonin receptor 0.0105 0.3802 0.3974
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0105 0.3802 0.3824
Schistosoma mansoni amine GPCR 0.0105 0.3802 0.3824
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0105 0.3802 0.3802
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0761 0.0766
Brugia malayi nuclear hormone receptor 0.0039 0.0761 0.0796
Onchocerca volvulus 0.0105 0.3802 1
Brugia malayi putative neuropeptide receptor 0.0105 0.3802 0.3974
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.2764 0.2764
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0761 0.0761
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0083 0.2783 0.2783
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0105 0.3802 0.3824
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis protein kinase c epsilon type 0.0049 0.1222 0.1222
Brugia malayi GnHR receptor homolog 0.0105 0.3802 0.3974
Echinococcus granulosus 7tm_1 domain containing protein 0.0105 0.3802 0.3802
Echinococcus multilocularis g protein coupled receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0105 0.3802 0.3802
Schistosoma mansoni tyrosine kinase 0.0028 0.0241 0.0242
Trypanosoma brucei rac serine-threonine kinase, putative 0.0119 0.4451 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.2764 0.2779
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0105 0.3802 0.3802
Echinococcus granulosus serine/threonine protein kinase 0.0082 0.2716 0.2716
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0056 0.1544 0.1544
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus g protein coupled receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0137 0.5275 0.5275
Echinococcus granulosus biogenic amine 5HT receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis 0.005 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.0044 0.0976 0.0976
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0083 0.2783 0.5
Loa Loa (eye worm) G-protein coupled receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus tm gpcr rhodopsin 0.0105 0.3802 0.3802
Onchocerca volvulus 0.0105 0.3802 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0074 0.2359 0.2359
Brugia malayi Raf kinase 0.0231 0.9568 1
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Schistosoma mansoni tyrosine kinase 0.0086 0.2919 0.2936
Schistosoma mansoni neuropeptide receptor 0.0105 0.3802 0.3824
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0028 0.0241 0.0241
Trypanosoma cruzi Protein kinase B 0.0082 0.2716 0.7529
Loa Loa (eye worm) neuropeptide F receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0761 0.0761
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.2764 0.2779
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0105 0.3802 0.3802
Echinococcus granulosus hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis tyrosine protein kinase ABL1 0.024 1 1
Schistosoma mansoni tyrosine kinase 0.0091 0.316 0.3178
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0105 0.3802 0.3824
Echinococcus granulosus tachykinin peptides receptor 99D 0.0105 0.3802 0.3802
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Echinococcus multilocularis tyrosine protein kinase Fyn 0.009 0.3107 0.3107
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.2764 0.2764
Schistosoma mansoni neuropeptide receptor 0.0105 0.3802 0.3824
Echinococcus granulosus epidermal growth factor receptor 0.0091 0.316 0.316
Toxoplasma gondii AGC kinase 0.0115 0.4246 0.5
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0074 0.2374 0.2374
Echinococcus granulosus protein kinase c epsilon type 0.0049 0.1222 0.1222
Echinococcus granulosus g protein coupled receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis neuropeptide s receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.2764 0.2764
Schistosoma mansoni biogenic amine (5HT) receptor 0.0105 0.3802 0.3824
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.2764 0.2889
Echinococcus granulosus 7TM GPCR rhodopsin 0.0105 0.3802 0.3802
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0056 0.1544 0.1544
Echinococcus granulosus alpha 1A adrenergic receptor 0.0105 0.3802 0.3802
Schistosoma mansoni atypical protein kinase C 0.0049 0.1222 0.1228
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Onchocerca volvulus 0.0105 0.3802 1
Echinococcus granulosus neuropeptide receptor A26 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0976 0.0981
Loa Loa (eye worm) hypothetical protein 0.0044 0.0976 0.0976
Entamoeba histolytica protein kinase, putative 0.0119 0.4451 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0105 0.3802 0.3824
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.2764 0.2764
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0105 0.3802 0.3802
Onchocerca volvulus 0.0105 0.3802 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0041 0.0846 0.0846
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.9944 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0976 0.0976
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0976 0.0976
Echinococcus granulosus neuropeptide FF receptor 2 0.0105 0.3802 0.3802
Echinococcus multilocularis thyroid hormone receptor alpha 0.0083 0.2764 0.2764
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.2764 0.2764
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Echinococcus multilocularis neuropeptide receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0105 0.3802 0.3802
Schistosoma mansoni biogenic amine receptor 0.0105 0.3802 0.3824
Schistosoma mansoni biogenic amine (5HT) receptor 0.0105 0.3802 0.3824
Echinococcus granulosus g protein coupled receptor 0.0105 0.3802 0.3802
Onchocerca volvulus 0.0105 0.3802 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0079 0.26 0.26
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0761 0.0766
Brugia malayi sulfakinin receptor protein 0.0105 0.3802 0.3974
Echinococcus multilocularis insulin receptor 0.0056 0.1544 0.1544
Echinococcus granulosus nervana 2 0.0074 0.2374 0.2374
Echinococcus granulosus rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Loa Loa (eye worm) raf kinase 0.0234 0.9704 0.9704
Schistosoma mansoni hypothetical protein 0.0105 0.3802 0.3824
Brugia malayi G-protein coupled receptor 0.0105 0.3802 0.3974
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi Tyrosine-protein kinase abl-1 0.0138 0.5314 0.5554
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0055 0.1512 0.1512
Loa Loa (eye worm) TK/EGFR protein kinase 0.0166 0.6595 0.6595
Onchocerca volvulus 0.0105 0.3802 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi hypothetical protein 0.0044 0.0976 0.102
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0105 0.3802 0.3974
Echinococcus granulosus serine:threonine protein kinase N2 0.0041 0.0846 0.0846
Trichomonas vaginalis AGC family protein kinase 0.0119 0.4451 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0105 0.3802 0.3824
Loa Loa (eye worm) hypothetical protein 0.0041 0.0846 0.0846
Schistosoma mansoni opsin-like receptor 0.0105 0.3802 0.3824
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis tyrosine protein kinase HCK 0.0068 0.208 0.208
Echinococcus granulosus fmrfamide receptor 0.0105 0.3802 0.3802
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0846 0.0368
Schistosoma mansoni opsin-like receptor 0.0105 0.3802 0.3824
Echinococcus multilocularis somatostatin receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis nervana 2 0.0074 0.2374 0.2374
Echinococcus multilocularis G-protein coupled receptor, putative 0.0105 0.3802 0.3802
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0105 0.3802 0.3802
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Schistosoma mansoni nuclear receptor 0.0039 0.0761 0.0766
Echinococcus multilocularis neuropeptides capa receptor 0.0105 0.3802 0.3802
Echinococcus granulosus orexin receptor type 2 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Onchocerca volvulus Neuropeptide F receptor homolog 0.0105 0.3802 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.3139 0.3139
Entamoeba histolytica protein kinase, putative 0.0068 0.208 0.3423
Entamoeba histolytica protein kinase, putative 0.0055 0.1512 0.185
Echinococcus multilocularis allatostatin A receptor 0.0105 0.3802 0.3802
Brugia malayi Furin-like cysteine rich region family protein 0.0166 0.6595 0.6892
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Schistosoma mansoni serine/threonine-protein kinase 0.0082 0.2716 0.2731
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Echinococcus multilocularis neuropeptides capa receptor 0.0105 0.3802 0.3802
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.2764 0.2889
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0761 0.0766
Echinococcus granulosus tyrosine kinase 0.0079 0.26 0.26
Echinococcus multilocularis tyrosine protein kinase Src64B 0.009 0.3107 0.3107
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0105 0.3802 0.3824
Onchocerca volvulus 0.0105 0.3802 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0761 0.0761
Trichomonas vaginalis AGC family protein kinase 0.0119 0.4451 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0105 0.3802 0.3802
Echinococcus granulosus tyrosine protein kinase Fyn 0.009 0.3107 0.3107
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Echinococcus granulosus dual specificity mitogen activated protein 0.0083 0.2783 0.2783
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0082 0.2716 0.7529
Schistosoma mansoni myosin xvIII 0.0105 0.3802 0.3824
Schistosoma mansoni zinc finger protein 0.0039 0.0761 0.0766
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.2764 0.2764
Echinococcus multilocularis serine:threonine protein kinase N2 0.0041 0.0846 0.0846
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0761 0.0761
Echinococcus multilocularis dual specificity mitogen activated protein 0.0083 0.2783 0.2783
Echinococcus multilocularis sex peptide receptor 0.0105 0.3802 0.3802
Trichomonas vaginalis AGC family protein kinase 0.0119 0.4451 1
Onchocerca volvulus 0.0083 0.2764 0.6585
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.2764 0.2764
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Onchocerca volvulus 0.0105 0.3802 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0976 0.0976
Loa Loa (eye worm) TK/ABL protein kinase 0.024 1 1
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0077 0.2512 0.5
Echinococcus granulosus nervana 2 0.0074 0.2374 0.2374
Schistosoma mansoni thyroid hormone receptor 0.0083 0.2764 0.2779
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0761 0.0796
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0083 0.2783 0.2908
Trichomonas vaginalis AGC family protein kinase 0.0055 0.1512 0.2149
Brugia malayi hypothetical protein 0.0039 0.0761 0.0796
Schistosoma mansoni amine GPCR 0.0105 0.3802 0.3824
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.2764 0.2889
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0041 0.0846 0.0846
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.2764 0.2889
Echinococcus multilocularis tyrosine protein kinase Fyn 0.009 0.3107 0.3107
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.2764 0.2779
Echinococcus granulosus rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0761 0.0761
Brugia malayi hypothetical protein 0.0044 0.0976 0.102
Echinococcus multilocularis serine:threonine protein kinase 38 0.0041 0.0846 0.0846
Brugia malayi SRC-1 0.009 0.3107 0.3247
Brugia malayi Dopamine receptor protein 2 0.0105 0.3802 0.3974
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi conserved hypotetical protein 0.0039 0.0761 0.0796
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi nuclear receptor NHR-67 0.0039 0.0761 0.0796
Trichomonas vaginalis AGC family protein kinase 0.0055 0.1512 0.2149
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.2764 0.2764
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0105 0.3802 0.3802
Echinococcus multilocularis fmrfamide receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0041 0.0846 0.0846
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.2764 0.2764
Echinococcus granulosus Protein kinase C brain isozyme 0.0049 0.1222 0.1222
Echinococcus multilocularis tyrosine protein kinase Fgr 0.009 0.3107 0.3107
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0846 0.0368
Echinococcus multilocularis orexin receptor type 2 0.0105 0.3802 0.3802
Loa Loa (eye worm) AGC/PKN protein kinase 0.0041 0.0846 0.0846
Schistosoma mansoni neuropeptide receptor 0.0105 0.3802 0.3824
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.2764 0.2764
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Onchocerca volvulus 0.0105 0.3802 1
Schistosoma mansoni neuropeptide receptor 0.0105 0.3802 0.3824
Echinococcus multilocularis G protein coupled receptor 139 0.0105 0.3802 0.3802
Echinococcus granulosus serine threonine protein kinase nrc 0.0077 0.2512 0.2512
Brugia malayi Protein kinase domain containing protein 0.0041 0.0846 0.0884
Trichomonas vaginalis AGC family protein kinase 0.0119 0.4451 1
Brugia malayi follicle stimulating hormone receptor 0.0105 0.3802 0.3974
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.2764 0.2764
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0761 0.0766
Echinococcus granulosus rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Loa Loa (eye worm) TK/INSR protein kinase 0.0056 0.1544 0.1544
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0074 0.2374 0.2374
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.2764 0.2889
Echinococcus multilocularis serotonin receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) AGC/AKT protein kinase 0.0119 0.4451 0.4451
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Echinococcus multilocularis epidermal growth factor receptor 0.0166 0.6595 0.6595
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0761 0.0761
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0761 0.0761
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0083 0.2783 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0761 0.0761
Schistosoma mansoni neuropeptide F-like receptor 0.0105 0.3802 0.3824
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni hypothetical protein 0.0105 0.3802 0.3824
Trichomonas vaginalis STE family protein kinase 0.0083 0.2783 0.5544
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.009 0.3107 0.3107
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.2764 0.6585
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0105 0.3802 0.3824
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.2764 0.2764
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0976 0.0981
Echinococcus multilocularis Glutaredoxin protein 5 0.0074 0.2374 0.2374
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni protein kinase 0.0083 0.2783 0.2798
Schistosoma mansoni serine/threonine kinase 0.0041 0.0846 0.085
Echinococcus granulosus biogenic amine 5HT receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) TK protein kinase 0.0079 0.26 0.26
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.2764 0.6585
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Echinococcus granulosus protein kinase c iota type 0.0049 0.1222 0.1222
Trichomonas vaginalis AGC family protein kinase 0.0055 0.1512 0.2149
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Trichomonas vaginalis STE family protein kinase 0.0083 0.2783 0.5544
Trichomonas vaginalis AGC family protein kinase 0.0045 0.105 0.0914
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0105 0.3802 0.3974
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0846 0.085
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi Tachykinin-like peptides receptor 99D 0.0105 0.3802 0.3974
Brugia malayi tailless protein 0.0039 0.0761 0.0796
Echinococcus multilocularis protein kinase c iota type 0.0049 0.1222 0.1222
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni growth hormone secretagogue receptor 0.0105 0.3802 0.3824
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.2764 0.2764
Entamoeba histolytica protein kinase, putative 0.0115 0.4246 0.9433
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.2764 0.2764
Echinococcus granulosus raf serine:threonine protein kinase 0.0239 0.9944 0.9944
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0041 0.0846 0.0846
Echinococcus granulosus epidermal growth factor receptor 0.0166 0.6595 0.6595
Echinococcus multilocularis tyrosine protein kinase Srms 0.0079 0.26 0.26
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0041 0.0846 0.0846
Giardia lamblia Kinase, STE STE20 0.0083 0.2783 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0105 0.3802 0.3824
Schistosoma mansoni tyrosine kinase 0.0028 0.0241 0.0242
Brugia malayi nuclear hormone receptor 0.0083 0.2764 0.2889
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.2764 0.2889
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0105 0.3802 0.3802
Onchocerca volvulus 0.0105 0.3802 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.2764 0.2889
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0761 0.0761
Brugia malayi hypothetical protein 0.0039 0.0761 0.0796
Onchocerca volvulus 0.0105 0.3802 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0761 0.0796
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0041 0.0846 0.0846
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.2764 0.2764
Echinococcus multilocularis fmrfamide receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.2764 0.2764
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus serotonin receptor 0.0105 0.3802 0.3802
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.2764 0.2779
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.2764 0.2764
Brugia malayi nuclear receptor RXR 0.0039 0.0761 0.0796
Trichomonas vaginalis AGC family protein kinase 0.0119 0.4451 1
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0976 0.102
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Brugia malayi nuclear receptor RXR 0.0044 0.0976 0.102
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.1222 0.1228
Brugia malayi Protein kinase domain containing protein 0.0041 0.0846 0.0884
Trichomonas vaginalis AGC family protein kinase 0.0119 0.4451 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.2764 0.2889
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Echinococcus multilocularis neuropeptide receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0055 0.1512 0.1512
Loa Loa (eye worm) hypothetical protein 0.0044 0.0976 0.0976
Echinococcus granulosus rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0055 0.1512 0.1512
Echinococcus granulosus rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Entamoeba histolytica protein kinase, putative 0.0119 0.4451 1
Brugia malayi ORL1-like opioid receptor 0.0105 0.3802 0.3974
Schistosoma mansoni serine/threonine-protein kinase 0.0082 0.2716 0.2731
Schistosoma mansoni coup transcription factor 0.0083 0.2764 0.2779
Schistosoma mansoni tyrosine kinase 0.0056 0.1544 0.1552
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0049 0.1222 0.1222
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0761 0.0761
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0105 0.3802 0.3802
Brugia malayi ecdysone receptor 0.0039 0.0761 0.0796
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0041 0.0846 0.0846
Echinococcus multilocularis epidermal growth factor receptor 0.0091 0.316 0.316
Echinococcus multilocularis g protein coupled receptor 0.0105 0.3802 0.3802
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0846 0.085
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0761 0.0796
Brugia malayi RE15519p 0.0105 0.3802 0.3974
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0041 0.0846 0.0846
Echinococcus multilocularis tyrosine protein kinase Src42A 0.009 0.3107 0.3107
Echinococcus granulosus insulin receptor 0.0056 0.1544 0.1544
Schistosoma mansoni tyrosine kinase 0.0056 0.1544 0.1552
Schistosoma mansoni biogenic amine receptor 0.0105 0.3802 0.3824
Brugia malayi larval opioid receptor 0.0105 0.3802 0.3974
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.1512 0.1521
Echinococcus granulosus tyrosine protein kinase Fyn 0.009 0.3107 0.3107
Echinococcus multilocularis serine:threonine protein kinase N2 0.0041 0.0846 0.0846
Echinococcus granulosus rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Onchocerca volvulus 0.0105 0.3802 1
Schistosoma mansoni amine GPCR 0.0105 0.3802 0.3824
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.2764 0.2764
Brugia malayi Protein kinase domain containing protein 0.0056 0.1544 0.1613
Brugia malayi Protein kinase domain containing protein 0.0055 0.1512 0.1581
Onchocerca volvulus 0.0105 0.3802 1
Onchocerca volvulus 0.0105 0.3802 1
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0761 0.0761
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.2764 0.2889
Brugia malayi p70 ribosomal S6 kinase beta 0.0115 0.4246 0.4438
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.009 0.3107 0.3107
Echinococcus multilocularis neuropeptide receptor A26 0.0105 0.3802 0.3802
Loa Loa (eye worm) TYRA-2 protein 0.0105 0.3802 0.3802
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.2764 0.6585
Schistosoma mansoni thyroid hormone receptor 0.0083 0.2764 0.2779
Schistosoma mansoni adenoreceptor 0.0105 0.3802 0.3824
Echinococcus granulosus G protein coupled receptor 139 0.0105 0.3802 0.3802
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0105 0.3802 0.3824
Schistosoma mansoni histamine h1 receptor 0.0105 0.3802 0.3824
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi Tyrosine-protein kinase abl-1 0.0113 0.4166 0.4354
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Schistosoma mansoni amine GPCR 0.0105 0.3802 0.3824
Echinococcus granulosus Glutaredoxin protein 5 0.0074 0.2374 0.2374
Schistosoma mansoni neuropeptide F-like receptor 0.0105 0.3802 0.3824
Brugia malayi phosphoinositide-dependent protein kinase I 0.0055 0.1512 0.1581
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.2764 0.2779
Echinococcus granulosus neuropeptide receptor 0.0105 0.3802 0.3802
Echinococcus granulosus rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Brugia malayi Dopamine receptor 0.0105 0.3802 0.3974
Echinococcus granulosus peptide allatostatin:somatostatin 0.0105 0.3802 0.3802
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.2764 0.2779
Echinococcus granulosus tyrosine protein kinase Src64B 0.009 0.3107 0.3107
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.009 0.3107 0.3107
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0115 0.4246 0.4246
Onchocerca volvulus 0.0105 0.3802 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.2764 0.2779
Schistosoma mansoni biogenic amine receptor 0.0105 0.3802 0.3824
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0077 0.2512 0.2512
Schistosoma mansoni opsin-like receptor 0.0105 0.3802 0.3824
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0077 0.2512 0.2512
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0976 0.0976
Echinococcus multilocularis serine threonine protein kinase 0.0041 0.0846 0.0846
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0761 0.0796
Entamoeba histolytica protein kinase 2, putative 0.0077 0.2512 0.4621
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.2764 0.2889
Echinococcus multilocularis neuropeptide Y receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0074 0.2359 0.2359
Schistosoma mansoni nuclear hormone receptor 0.0083 0.2764 0.2779
Echinococcus granulosus dro:myosuppressin receptor 0.0105 0.3802 0.3802
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0105 0.3802 0.3802
Schistosoma mansoni nuclear receptor 0.0039 0.0761 0.0766
Echinococcus granulosus FTZ F1 alpha 0.0083 0.2764 0.2764
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus tyrosine protein kinase Fyn 0.009 0.3107 0.3107
Brugia malayi neuropeptide F receptor 0.0105 0.3802 0.3974
Echinococcus granulosus tyrosine protein kinase Blk 0.0079 0.26 0.26
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.009 0.3107 0.3107
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.1222 0.1228
Loa Loa (eye worm) AGC/NDR protein kinase 0.0041 0.0846 0.0846
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus neuropeptide Y receptor 0.0105 0.3802 0.3802
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.2764 0.2779
Echinococcus multilocularis serotonin receptor 0.0105 0.3802 0.3802
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.2764 0.2889
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0761 0.0796
Schistosoma mansoni tyrosine kinase 0.0229 0.948 0.9533
Echinococcus granulosus sex peptide receptor 0.0105 0.3802 0.3802
Brugia malayi Dopamine receptor protein 1 0.0105 0.3802 0.3974
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Loa Loa (eye worm) G-protein coupled receptor 0.0105 0.3802 0.3802
Echinococcus granulosus g-protein coupled receptor 0.0105 0.3802 0.3802
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.2764 0.2889
Echinococcus granulosus allatostatin A receptor 0.0105 0.3802 0.3802
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Loa Loa (eye worm) SRC-1 0.009 0.3107 0.3107
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.2764 0.2779
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.1222 0.1228
Schistosoma mansoni tyrosine kinase 0.0166 0.6595 0.6632
Echinococcus granulosus neuropeptide s receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0079 0.26 0.26
Echinococcus granulosus tm gpcr rhodopsin 0.0105 0.3802 0.3802
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0976 0.0976
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0055 0.1512 0.1512
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0091 0.316 0.316
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0761 0.0766
Brugia malayi neuropeptide F receptor 0.0105 0.3802 0.3974
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi G protein-coupled receptor 0.0105 0.3802 0.3974
Echinococcus multilocularis dro:myosuppressin receptor 0.0105 0.3802 0.3802
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Trichomonas vaginalis AGC family protein kinase 0.0119 0.4451 1
Brugia malayi Hr1 repeat family protein 0.0041 0.0846 0.0884
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.2764 0.2764
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.009 0.3107 0.3107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0761 0.0761
Onchocerca volvulus 0.0105 0.3802 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0105 0.3802 0.3802
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0976 0.102
Echinococcus multilocularis rac serine:threonine kinase 0.0082 0.2716 0.2716
Echinococcus granulosus c src tyrosine kinase 0.0028 0.0241 0.0241
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0105 0.3802 0.3802
Brugia malayi hypothetical protein 0.0105 0.3802 0.3974
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.2764 0.2889
Brugia malayi protein kinase C II. 0.0049 0.1222 0.1277
Schistosoma mansoni alpha-1 adrenergic receptor 0.0105 0.3802 0.3824
Echinococcus granulosus tm gpcr rhodopsin 0.0105 0.3802 0.3802
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0105 0.3802 0.3802
Brugia malayi protein-tyrosine kinase 0.0079 0.26 0.2717
Echinococcus granulosus neuropeptides capa receptor 0.0105 0.3802 0.3802
Schistosoma mansoni neuropeptide f receptor 76f 0.0105 0.3802 0.3824
Brugia malayi AKH receptor 0.0105 0.3802 0.3974
Loa Loa (eye worm) DR-78 0.0039 0.0761 0.0761
Schistosoma mansoni vav2 0.0024 0.0073 0.0074
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0105 0.3802 1
Schistosoma mansoni tyrosine kinase 0.0086 0.2919 0.2936
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus tyrosine protein kinase HCK 0.0068 0.208 0.208
Echinococcus granulosus neuropeptide receptor 0.0105 0.3802 0.3802
Brugia malayi nuclear receptor NHR-88 0.0083 0.2764 0.2889
Schistosoma mansoni hypothetical protein 0.0105 0.3802 0.3824
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.2764 0.2764
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0028 0.0241 0.0242
Schistosoma mansoni tyrosine kinase 0.0086 0.2919 0.2936
Loa Loa (eye worm) hypothetical protein 0.0083 0.2764 0.2764
Echinococcus granulosus tyrosine protein kinase Lyn 0.0093 0.3244 0.3244
Echinococcus granulosus neuropeptide Y receptor 0.0105 0.3802 0.3802
Schistosoma mansoni amine GPCR 0.0105 0.3802 0.3824
Schistosoma mansoni tyrosine kinase 0.009 0.3107 0.3124
Echinococcus multilocularis tyrosine protein kinase Fyn 0.009 0.3107 0.3107
Echinococcus multilocularis g protein coupled receptor 0.0105 0.3802 0.3802
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.2764 0.2889
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Brugia malayi Melatonin receptor type 1A 0.0105 0.3802 0.3974
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0028 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0761 0.0761
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0761 0.0761
Loa Loa (eye worm) melatonin receptor type 1A 0.0105 0.3802 0.3802
Echinococcus granulosus protein kinase C gamma type 0.0041 0.0846 0.0846
Brugia malayi Serotonin receptor 0.0105 0.3802 0.3974
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0105 0.3802 0.3824
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.2764 0.2764
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Echinococcus granulosus tyrosine protein kinase Src42A 0.009 0.3107 0.3107
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Echinococcus granulosus NDR protein kinase 0.0041 0.0846 0.0846
Echinococcus multilocularis raf serine:threonine protein kinase 0.0239 0.9944 0.9944
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0105 0.3802 0.3974
Schistosoma mansoni hypothetical protein 0.0105 0.3802 0.3824
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0105 0.3802 0.3802
Echinococcus multilocularis tyrosine protein kinase Abl 0.0113 0.4166 0.4166
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0105 0.3802 0.3974
Loa Loa (eye worm) neuropeptide F receptor 0.0105 0.3802 0.3802
Brugia malayi putative neuropeptide receptor NPR1 0.0105 0.3802 0.3974
Brugia malayi G protein-coupled receptor F59B2.13 0.0105 0.3802 0.3974
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0049 0.1222 0.1222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.2764 0.2764
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0105 0.3802 0.3974
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0761 0.0761
Brugia malayi nuclear receptor NHR-88 0.0039 0.0761 0.0796
Loa Loa (eye worm) hypothetical protein 0.0105 0.3802 0.3802
Brugia malayi ecdysteroid receptor 0.0083 0.2764 0.2889
Echinococcus multilocularis g-protein coupled receptor 0.0105 0.3802 0.3802
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.2764 0.2889
Loa Loa (eye worm) hypothetical protein 0.0039 0.0761 0.0761
Echinococcus granulosus neuropeptides capa receptor 0.0105 0.3802 0.3802
Echinococcus multilocularis rhodopsin orphan GPCR 0.0105 0.3802 0.3802
Brugia malayi Protein kinase domain containing protein 0.0119 0.4451 0.4651
Echinococcus multilocularis nervana 2 0.0074 0.2374 0.2374

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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