Detailed information for compound 923576

Basic information

Technical information
  • TDR Targets ID: 923576
  • Name: (2S)-2-[[(2S)-2-amino-5-(diaminomethylideneam ino)pentanoyl]amino]-3-(4-hydroxyphenyl)propa noic acid
  • MW: 337.374 | Formula: C15H23N5O4
  • H donors: 6 H acceptors: 4 LogP: -2.84 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: NC(=N)NCCC[C@@H](C(=O)N[C@H](C(=O)O)Cc1ccc(cc1)O)N
  • InChi: 1S/C15H23N5O4/c16-11(2-1-7-19-15(17)18)13(22)20-12(14(23)24)8-9-3-5-10(21)6-4-9/h3-6,11-12,21H,1-2,7-8,16H2,(H,20,22)(H,23,24)(H4,17,18,19)/t11-,12-/m0/s1
  • InChiKey: XTWSWDJMIKUJDQ-RYUDHWBXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2S)-2-[[(2S)-2-amino-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
  • (2S)-2-[[(2S)-2-amino-5-guanidino-1-oxopentyl]amino]-3-(4-hydroxyphenyl)propanoic acid
  • (2S)-2-[[(2S)-2-amino-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propionic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neuropeptide s receptor 0.0308 0.1582 0.1582
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0035 0.0035
Onchocerca volvulus 0.0318 0.1634 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0316 0.0316
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0104 0.0104
Onchocerca volvulus Huntingtin homolog 0.0066 0.0286 0.1341
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0026 0.0026
Echinococcus granulosus peregrin 0.0032 0.0104 0.0104
Schistosoma mansoni axis inhibition protein axin 0.0017 0.0026 0.0026
Echinococcus multilocularis musashi 0.0057 0.0239 0.0239
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0027 0.0077 0.0077
Brugia malayi hypothetical protein 0.0017 0.0026 0.0026
Echinococcus multilocularis lamin 0.0057 0.0239 0.0239
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0104 0.0104
Plasmodium vivax SET domain protein, putative 0.0027 0.0077 0.737
Leishmania major hypothetical protein, conserved 0.0019 0.0035 1
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0035 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0026 0.0026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0026 0.007 0.007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0026 0.007 0.007
Schistosoma mansoni lamin 0.0057 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.1883 1 1
Loa Loa (eye worm) carboxylesterase 0.1883 1 1
Onchocerca volvulus 0.0318 0.1634 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0017 0.0026 0.0026
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0017 0.0026 0.0026
Brugia malayi Carboxylesterase family protein 0.0318 0.1634 0.1634
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0138 0.0669 0.0669
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0017 0.0026 0.0026
Onchocerca volvulus 0.0057 0.0239 0.1041
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0385 0.0385
Schistosoma mansoni jumonji domain containing protein 0.0116 0.0554 0.0554
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0318 0.1634 0.1634
Echinococcus multilocularis expressed protein 0.0336 0.1728 0.1728
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0057 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0318 0.1634 0.1634
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0104 1
Brugia malayi A-kinase anchor protein 10, precursor 0.0017 0.0026 0.0026
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0026 0.0072 0.0072
Echinococcus granulosus regulator of G protein signaling 3 0.0017 0.0026 0.0026
Echinococcus granulosus axis inhibition protein axin 0.0017 0.0026 0.0026
Trichomonas vaginalis spcc417.12 protein, putative 0.0318 0.1634 1
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0026 0.0156
Loa Loa (eye worm) transcription factor SMAD2 0.0072 0.0317 0.0317
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0318 0.1634 0.1634
Entamoeba histolytica hypothetical protein 0.0017 0.0026 0.5228
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0035
Brugia malayi Regulator of G protein signaling domain containing protein 0.0017 0.0026 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0077 0.0077
Brugia malayi Carboxylesterase family protein 0.0318 0.1634 0.1634
Loa Loa (eye worm) hypothetical protein 0.0163 0.0803 0.0803
Brugia malayi regulator of G-protein signaling rgs-7 0.0017 0.0026 0.0026
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0286 0.0286
Entamoeba histolytica hypothetical protein 0.0017 0.0026 0.5228
Echinococcus granulosus carboxylesterase 5A 0.1883 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0308 0.1582 0.1582
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0318 0.1634 0.1634
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0026
Brugia malayi Bromodomain containing protein 0.0032 0.0104 0.0104
Giardia lamblia PHD finger protein 15 0.0032 0.0104 1
Plasmodium falciparum phd finger protein, putative 0.0032 0.0104 1
Brugia malayi Carboxylesterase family protein 0.0318 0.1634 0.1634
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0026 0.0156
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0022 0.0049 0.0049
Plasmodium vivax JmjC domain containing protein 0.0019 0.0035 0.3397
Echinococcus granulosus BC026374 protein S09 family 0.0318 0.1634 0.1634
Loa Loa (eye worm) PXA domain-containing protein 0.0017 0.0026 0.0026
Trichomonas vaginalis set domain proteins, putative 0.0213 0.1072 0.656
Brugia malayi Regulator of G protein signaling domain containing protein 0.0017 0.0026 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0027 0.0077 0.0077
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0027 0.0077 0.737
Loa Loa (eye worm) RGS-3 protein 0.0017 0.0026 0.0026
Brugia malayi PHD-finger family protein 0.0032 0.0104 0.0104
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0026 0.007 0.007
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0026 0.0156
Echinococcus multilocularis lamin dm0 0.0057 0.0239 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0026 0.0156
Brugia malayi hypothetical protein 0.0109 0.0519 0.0519
Onchocerca volvulus Huntingtin homolog 0.0066 0.0286 0.1341
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0138 0.0669 0.0669
Schistosoma mansoni hypothetical protein 0.0022 0.0049 0.0049
Schistosoma mansoni z-protein (S1r protein) 0.0017 0.0026 0.0026
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0239 0.0239
Echinococcus granulosus neuropeptide receptor A26 0.0308 0.1582 0.1582
Echinococcus multilocularis para nitrobenzyl esterase 0.0318 0.1634 0.1634
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0035 0.0035
Brugia malayi hypothetical protein 0.0318 0.1634 0.1634
Brugia malayi Pre-SET motif family protein 0.0027 0.0077 0.0077
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0285 0.1459 0.1459
Brugia malayi PXA domain containing protein 0.0017 0.0026 0.0026
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0318 0.1634 0.1634
Echinococcus multilocularis acetylcholinesterase 0.1883 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0022 0.0049 0.0049
Echinococcus granulosus acetylcholinesterase 0.1883 1 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0318 0.1634 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0017 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0318 0.1634 0.1634
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0035 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0035
Treponema pallidum exodeoxyribonuclease (exoA) 0.0012 0 0.5
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0035 0.0035
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0026 0.0026
Echinococcus multilocularis axis inhibition protein axin 0.0017 0.0026 0.0026
Brugia malayi Carboxylesterase family protein 0.0318 0.1634 0.1634
Echinococcus multilocularis regulator of G protein signaling 3 0.0017 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0066 0.0286 0.0286
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0026 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0026 0.0156
Brugia malayi intermediate filament protein 0.0057 0.0239 0.0239
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0035
Echinococcus multilocularis BC026374 protein (S09 family) 0.0318 0.1634 0.1634
Echinococcus multilocularis regulator of G protein signaling 3 0.0017 0.0026 0.0026
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0026 0.0026
Echinococcus multilocularis lysine specific demethylase 5A 0.0072 0.0316 0.0316
Schistosoma mansoni intermediate filament proteins 0.0057 0.0239 0.0239
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0026 0.007 0.007
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0318 0.1634 0.1634
Entamoeba histolytica hypothetical protein 0.0017 0.0026 0.5228
Echinococcus granulosus intermediate filament protein 0.0057 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0075
Schistosoma mansoni acetylcholinesterase 0.0318 0.1634 0.1634
Schistosoma mansoni axis inhibition protein axin 0.0017 0.0026 0.0026
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0035
Brugia malayi Pre-SET motif family protein 0.0187 0.0934 0.0934
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0017 0.0026 0.0026
Schistosoma mansoni transcription factor LCR-F1 0.0022 0.0049 0.0049
Brugia malayi jmjC domain containing protein 0.0072 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0027 0.0077 0.0077
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0026
Onchocerca volvulus 0.0318 0.1634 1
Schistosoma mansoni hypothetical protein 0.0032 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0318 0.1634 0.1634
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0026 0.0156
Loa Loa (eye worm) hypothetical protein 0.0066 0.0286 0.0286
Brugia malayi PXA domain containing protein 0.0017 0.0026 0.0026
Echinococcus granulosus acetylcholinesterase 0.1883 1 1
Echinococcus multilocularis neuroligin 0.0318 0.1634 0.1634
Brugia malayi hypothetical protein 0.0163 0.0803 0.0803
Echinococcus granulosus lamin dm0 0.0057 0.0239 0.0239
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0012 0 0.5
Echinococcus granulosus Regulator of G protein signaling 20 0.0017 0.0026 0.0026
Echinococcus granulosus lysine specific demethylase 5A 0.0072 0.0316 0.0316
Brugia malayi Stress-activated protein kinase jnk-1 0.0085 0.0385 0.0385
Echinococcus multilocularis acetylcholinesterase 0.1883 1 1
Echinococcus granulosus phd:f box containing protein 0.0019 0.0035 0.0035
Brugia malayi hypothetical protein 0.0017 0.0026 0.0026
Onchocerca volvulus 0.0213 0.1072 0.639
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0026 0.007 0.007
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0017 0.0026 0.0026
Loa Loa (eye worm) MH2 domain-containing protein 0.0072 0.0317 0.0317
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0026 0.0026
Echinococcus granulosus axis inhibition protein axin 0.0017 0.0026 0.0026
Onchocerca volvulus 0.0318 0.1634 1
Onchocerca volvulus Alhambra homolog 0.0032 0.0104 0.0176
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0318 0.1634 1
Echinococcus multilocularis regulator of G protein signaling 0.0017 0.0026 0.0026
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0318 0.1634 0.1634
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0035 0.0035
Brugia malayi hypothetical protein 0.0066 0.0286 0.0286
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0035 0.0035
Echinococcus multilocularis beta adrenergic receptor kinase 0.0017 0.0026 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0027 0.0077 0.0077
Onchocerca volvulus 0.0057 0.0239 0.1041
Echinococcus granulosus neuroligin 0.0318 0.1634 0.1634
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0035 0.0035
Echinococcus granulosus regulator of G protein signaling 3 0.0017 0.0026 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0026 0.007 0.007
Brugia malayi hypothetical protein 0.0022 0.0049 0.0049
Onchocerca volvulus 0.0318 0.1634 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0026 0.007 0.007
Brugia malayi regulator of G-protein signaling egl-10 0.0017 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0318 0.1634 0.1634
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1883 1 1
Echinococcus granulosus neuropeptide s receptor 0.0308 0.1582 0.1582
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0026 0.0026
Schistosoma mansoni gliotactin 0.0318 0.1634 0.1634
Echinococcus granulosus beta-adrenergic receptor kinase 0.0017 0.0026 0.0026
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0104 0.0104
Brugia malayi Carboxylesterase family protein 0.1883 1 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0017 0.0026 0.0026
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0017 0.0026 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0026 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0081
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0239 0.0239
Brugia malayi jmjC domain containing protein 0.0019 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0026
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0017 0.0026 0.0026
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0035 0.0035
Schistosoma mansoni neuroligin 3 (S09 family) 0.0318 0.1634 0.1634
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0318 0.1634 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.0104
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0239 0.0239
Echinococcus granulosus c-Jun N-terminal kinases 0.0085 0.0385 0.0385
Onchocerca volvulus 0.0163 0.0803 0.4659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0077 0.0077
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0035 0.0035
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0017 0.0026 0.0026
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0171 0.0171
Echinococcus granulosus para nitrobenzyl esterase 0.0318 0.1634 0.1634
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0035 0.0035
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0104 1
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0026 0.0026
Schistosoma mansoni BC026374 protein (S09 family) 0.0318 0.1634 0.1634
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0035 0.0035
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0035 0.3397
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0026
Loa Loa (eye worm) acetylcholinesterase 1 0.1883 1 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0081 0.0081
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0035 0.0035
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0035 0.0035
Brugia malayi jmjC domain containing protein 0.0138 0.0669 0.0669
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0035 0.0035
Echinococcus granulosus lamin 0.0057 0.0239 0.0239
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0035 0.3397
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0035 0.3397
Entamoeba histolytica hypothetical protein 0.0022 0.0049 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0035 1
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0097 0.0097
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0104 1
Loa Loa (eye worm) carboxylesterase 0.0318 0.1634 0.1634
Brugia malayi MH2 domain containing protein 0.0072 0.0317 0.0317
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0187 0.0934 0.0934
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0316 0.0316
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0104 0.0104
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0056 0.0234 0.0234
Echinococcus multilocularis axis inhibition protein axin 0.0017 0.0026 0.0026
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0017 0.0026 0.0156
Loa Loa (eye worm) hypothetical protein 0.0318 0.1634 0.1634
Echinococcus multilocularis peregrin 0.0032 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0318 0.1634 0.1634
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0026 0.007 0.007
Entamoeba histolytica hypothetical protein 0.0022 0.0049 1
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0026 0.0026
Schistosoma mansoni lamin 0.0057 0.0239 0.0239
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0064 0.0273 0.0273
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0318 0.1634 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0026 0.0026
Echinococcus multilocularis carboxylesterase 5A 0.1883 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0026
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0085 0.0385 0.0385
Echinococcus granulosus histone lysine methyltransferase setb 0.0027 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0035
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0035 1
Echinococcus granulosus expressed protein 0.0336 0.1728 0.1728
Mycobacterium ulcerans carboxylesterase, LipT 0.0318 0.1634 1
Loa Loa (eye worm) hypothetical protein 0.1883 1 1
Entamoeba histolytica hypothetical protein 0.0022 0.0049 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0035 0.0035
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0085 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0026
Loa Loa (eye worm) carboxylesterase 0.0318 0.1634 0.1634
Entamoeba histolytica hypothetical protein 0.0022 0.0049 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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