Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0091 | 0.0394 | 0.0394 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0088 | 0.0379 | 0.0379 |
Plasmodium falciparum | mitochondrial import inner membrane translocase subunit TIM23, putative | 0.004 | 0.0125 | 0.1501 |
Schistosoma mansoni | tar DNA-binding protein | 0.0855 | 0.4403 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0051 | 0.0183 | 0.0415 |
Schistosoma mansoni | tar DNA-binding protein | 0.0855 | 0.4403 | 1 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.002 | 0.0021 | 0.0141 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0348 | 0.174 | 0.2104 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0151 | 0.0343 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0097 | 0.0423 | 0.2835 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0001 | 0.0004 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0051 | 0.0183 | 0.0222 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0053 | 0.0353 |
Loa Loa (eye worm) | TAR-binding protein | 0.0855 | 0.4403 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0107 | 0.0475 | 0.0475 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0049 | 0.0171 | 0.0387 |
Brugia malayi | AMP-binding enzyme family protein | 0.0093 | 0.0402 | 0.0912 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0174 | 0.0829 | 0.1884 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0017 | 0.0003 | 0.0019 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0301 | 0.1493 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0066 | 0.0443 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0283 | 0.1401 | 0.3181 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0024 | 0.0042 | 0.0094 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0181 | 0.0864 | 0.5787 |
Echinococcus granulosus | dnaJ subfamily B | 0.0348 | 0.174 | 0.3952 |
Brugia malayi | beta-lactamase family protein | 0.0301 | 0.1493 | 0.3392 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0051 | 0.0183 | 0.0415 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0161 | 0.0161 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0125 | 0.0283 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0051 | 0.0183 | 0.0415 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0027 | 0.0057 | 0.0129 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.005 | 0.0333 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0051 | 0.0183 | 0.0417 |
Mycobacterium tuberculosis | Probable reductase | 0.0107 | 0.0475 | 0.0475 |
Schistosoma mansoni | methyltransferase-related | 0.0027 | 0.0059 | 0.0134 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0024 | 0.0042 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.118 | 0.2678 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0301 | 0.1493 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.001 | 0.001 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0023 | 0.0035 | 0.0235 |
Schistosoma mansoni | thyroid hormone receptor | 0.0334 | 0.1669 | 0.3791 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0021 | 0.0024 | 0.0162 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0023 | 0.0035 | 0.0423 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0151 | 0.0344 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.005 | 0.0333 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0051 | 0.0183 | 0.0417 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit Tim17 family protein | 0.004 | 0.0125 | 0.0283 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0125 | 0.0281 |
Schistosoma mansoni | nuclear hormone receptor | 0.0024 | 0.0042 | 0.0094 |
Schistosoma mansoni | hypothetical protein | 0.0218 | 0.1062 | 0.2411 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0051 | 0.0183 | 0.0417 |
Schistosoma mansoni | tar DNA-binding protein | 0.0855 | 0.4403 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0218 | 0.1062 | 0.2411 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0319 | 0.1592 | 0.3616 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0016 | 0.0105 |
Schistosoma mansoni | tar DNA-binding protein | 0.0855 | 0.4403 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0057 | 0.0128 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0023 | 0.0035 | 0.008 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0027 | 0.0057 | 0.0129 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0051 | 0.0183 | 0.0222 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0161 | 0.1935 |
Mycobacterium leprae | Probable lipase LipE | 0.0301 | 0.1493 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0024 | 0.0042 | 0.026 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0051 | 0.0183 | 0.0417 |
Onchocerca volvulus | 0.0301 | 0.1493 | 1 | |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0173 | 0.0393 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0021 | 0.0024 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.0725 | 0.1645 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0049 | 0.0171 | 0.259 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0161 | 0.0365 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.006 | 0.023 | 0.1524 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.005 | 0.0315 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit Tim17 family protein | 0.004 | 0.0125 | 0.0283 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0023 | 0.0035 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Echinococcus multilocularis | GPCR, family 2 | 0.0101 | 0.0446 | 0.0539 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.0446 | 0.1012 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0433 | 0.0981 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0051 | 0.0183 | 0.0417 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0049 | 0.0171 | 0.0206 |
Mycobacterium ulcerans | polyketide synthase | 0.0091 | 0.0394 | 0.2636 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0051 | 0.0183 | 0.0415 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.005 | 0.005 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0051 | 0.0183 | 0.0417 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0114 | 0.0514 | 0.1168 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0051 | 0.0183 | 0.0417 |
Schistosoma mansoni | zinc finger protein | 0.0024 | 0.0042 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.1062 | 0.241 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.005 | 0.0315 |
Brugia malayi | Probable ClpP-like protease | 0.0174 | 0.0829 | 0.1884 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0099 | 0.0433 | 0.0983 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0114 | 0.0516 | 0.1172 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0114 | 0.0516 | 0.0624 |
Mycobacterium ulcerans | hypothetical protein | 0.0021 | 0.0024 | 0.0162 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0039 | 0.0118 | 0.0792 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0051 | 0.0183 | 0.0417 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0241 | 0.118 | 0.1426 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0024 | 0.0042 | 0.0094 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0051 | 0.0183 | 0.1211 |
Schistosoma mansoni | nuclear receptor | 0.0024 | 0.0042 | 0.0094 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0051 | 0.0183 | 0.0417 |
Echinococcus granulosus | tumor protein p63 | 0.0674 | 0.3452 | 0.7841 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0021 | 0.0024 | 0.0029 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0181 | 0.0864 | 0.5787 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0051 | 0.0183 | 0.0222 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0174 | 0.0829 | 0.5554 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0049 | 0.0171 | 0.0386 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0105 | 0.0703 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0017 | 0.0003 | 0.0019 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0017 | 0.0003 | 0.0019 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0091 | 0.0394 | 0.2636 |
Loa Loa (eye worm) | RNA binding protein | 0.0855 | 0.4403 | 1 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0016 | 0.0001 | 0.0004 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.006 | 0.0231 | 0.155 |
Mycobacterium leprae | conserved hypothetical protein | 0.0301 | 0.1493 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0161 | 0.1935 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0097 | 0.0423 | 0.0423 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0093 | 0.0402 | 0.0911 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0016 | 0.0001 | 0.0004 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.0016 | 0.0105 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0029 | 0.0065 | 0.0065 |
Echinococcus granulosus | cpg binding protein | 0.0026 | 0.005 | 0.0114 |
Brugia malayi | beta-lactamase | 0.0301 | 0.1493 | 0.3392 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 1 |
Giardia lamblia | Methyltransferase like 2 | 0.0027 | 0.0059 | 0.3466 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0301 | 0.1493 | 0.1493 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0049 | 0.0171 | 0.0387 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0097 | 0.0423 | 0.2821 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0283 | 0.1401 | 0.1694 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0114 | 0.0514 | 0.0622 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0161 | 0.1075 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.005 | 0.0333 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0024 | 0.0042 | 0.0093 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0053 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0636 | 0.1443 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.001 | 0.001 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0161 | 0.1075 |
Leishmania major | hypothetical protein, conserved | 0.0301 | 0.1493 | 1 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0023 | 0.0035 | 0.0235 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.005 | 0.0113 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0161 | 0.0365 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0049 | 0.0171 | 0.0387 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0016 | 0.0001 | 0.0001 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0049 | 0.0171 | 0.1142 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0024 | 0.0042 | 0.005 |
Onchocerca volvulus | 0.0051 | 0.0183 | 0.1211 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.005 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Onchocerca volvulus | 0.0166 | 0.0788 | 0.5266 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0081 | 0.0541 |
Brugia malayi | ecdysone receptor | 0.0024 | 0.0042 | 0.0094 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.005 | 0.005 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0051 | 0.0183 | 0.0417 |
Toxoplasma gondii | mitochondrial inner membrane translocase subunit TIM17, putative | 0.004 | 0.0125 | 0.0834 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0051 | 0.0183 | 0.0417 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0161 | 0.0194 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0301 | 0.1493 | 0.1493 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0049 | 0.0171 | 0.1142 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0036 | 0.0105 | 0.0703 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0051 | 0.0183 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Mycobacterium ulcerans | polyketide synthase | 0.0097 | 0.0423 | 0.2835 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.0446 | 0.1012 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0039 | 0.0118 | 0.0792 |
Brugia malayi | ecdysteroid receptor | 0.0051 | 0.0183 | 0.0417 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0107 | 0.0475 | 0.3169 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0051 | 0.0183 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Schistosoma mansoni | hypothetical protein | 0.0348 | 0.174 | 0.3952 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0024 | 0.0042 | 0.0094 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0024 | 0.0042 | 0.0094 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.005 | 0.0333 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0091 | 0.0394 | 0.2622 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.006 | 0.023 | 0.2773 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0073 | 0.03 | 0.1994 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0161 | 0.1075 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0101 | 0.0446 | 0.0539 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0053 | 0.0354 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0301 | 0.1493 | 0.1806 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.0446 | 0.1012 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0301 | 0.1493 | 0.3392 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0051 | 0.0183 | 0.0417 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0301 | 0.1493 | 0.1493 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0024 | 0.0042 | 0.0093 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0027 | 0.0057 | 0.0129 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.005 | 0.0333 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0136 | 0.063 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0001 | 0.0004 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0101 | 0.0446 | 0.1012 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.005 | 0.0333 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0051 | 0.0183 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.005 | 0.0112 |
Onchocerca volvulus | 0.0301 | 0.1493 | 1 | |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0017 | 0.0003 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0016 | 0.0034 |
Echinococcus multilocularis | tumor protein p63 | 0.0674 | 0.3452 | 0.4174 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0097 | 0.0423 | 0.2821 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0101 | 0.0446 | 0.1011 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0031 | 0.0079 | 0.0079 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0051 | 0.0183 | 0.0417 |
Echinococcus granulosus | GPCR family 2 | 0.0101 | 0.0446 | 0.1012 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0119 | 0.0538 | 0.3588 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 1 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0039 | 0.0118 | 0.0793 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.0446 | 0.1012 |
Brugia malayi | Muscleblind-like protein | 0.0137 | 0.0636 | 0.1444 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0091 | 0.0394 | 0.2636 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0016 | 0.0034 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0091 | 0.0394 | 0.0394 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0017 | 0.0003 | 0.0006 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0301 | 0.1493 | 0.1493 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0029 | 0.0065 | 0.0419 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0171 | 0.1142 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0161 | 0.1075 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0021 | 0.0024 | 0.0162 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0024 | 0.0042 | 0.026 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0785 | 0.1782 |
Leishmania major | hypothetical protein, conserved | 0.0181 | 0.0864 | 0.5787 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0301 | 0.1493 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.001 | 0.001 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0119 | 0.0538 | 0.0538 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0516 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0119 | 0.0538 | 0.0538 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0091 | 0.0394 | 0.0394 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0021 | 0.0024 | 0.0024 |
Mycobacterium tuberculosis | Conserved protein | 0.0301 | 0.1493 | 0.1493 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0024 | 0.0042 | 0.005 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1591 | 0.827 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0301 | 0.1493 | 1 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0021 | 0.0024 | 0.0055 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0097 | 0.0423 | 0.0423 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.005 | 0.0113 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0001 | 0.0004 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0164 | 0.0778 | 0.52 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0047 | 0.0162 | 0.1087 |
Mycobacterium ulcerans | hypothetical protein | 0.0021 | 0.0024 | 0.0162 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0051 | 0.0183 | 0.0417 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0174 | 0.0829 | 0.5554 |
Loa Loa (eye worm) | DR-78 | 0.0024 | 0.0042 | 0.0093 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0097 | 0.0423 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0001 | 0.0004 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0059 | 0.0225 | 0.151 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0516 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 0.1884 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0057 | 0.0129 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0301 | 0.1493 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0024 | 0.0042 | 0.0094 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0073 | 0.03 | 0.2009 |
Onchocerca volvulus | 0.0093 | 0.0402 | 0.2676 | |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0024 | 0.0043 | 0.0096 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0171 | 0.1142 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0301 | 0.1493 | 0.3392 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0051 | 0.0183 | 0.0417 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0181 | 0.0864 | 0.5787 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0119 | 0.0538 | 0.0538 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0114 | 0.0514 | 0.0514 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0687 | 0.3525 | 0.4262 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0059 | 0.0396 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0091 | 0.0394 | 0.2636 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0065 | 0.0259 | 0.0259 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0024 | 0.0042 | 0.0094 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0051 | 0.0183 | 0.0417 |
Brugia malayi | steroid hormone receptor | 0.0051 | 0.0183 | 0.0417 |
Schistosoma mansoni | thyroid hormone receptor | 0.0334 | 0.1669 | 0.3791 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0076 | 0.0314 | 0.0314 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0017 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0301 | 0.1493 | 1 |
Onchocerca volvulus | 0.0049 | 0.0173 | 0.1141 | |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0516 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0334 | 0.1669 | 0.2018 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0052 | 0.0187 | 0.0424 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0035 | 0.0098 | 0.1037 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit Tim17 family protein | 0.004 | 0.0125 | 0.0283 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0051 | 0.0183 | 0.0417 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0516 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0017 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0099 | 0.0433 | 0.2884 | |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0029 | 0.0065 | 0.0437 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0023 | 0.0035 | 0.0235 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0151 | 0.0344 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0021 | 0.0024 | 0.0162 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0114 | 0.0516 | 0.1172 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.005 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0016 | 0.0034 |
Onchocerca volvulus | 0.0026 | 0.005 | 0.0315 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0027 | 0.0057 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.1493 | 0.3391 |
Echinococcus granulosus | geminin | 0.0166 | 0.0785 | 0.1782 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0051 | 0.0183 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.005 | 0.0112 |
Mycobacterium tuberculosis | Conserved protein | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0051 | 0.0183 | 0.0417 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0028 | 0.0062 | 0.0416 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0051 | 0.0183 | 0.0417 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0016 | 0.0001 | 0.0001 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0068 | 0.0453 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0105 | 0.0703 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0051 | 0.0183 | 0.0417 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0039 | 0.0118 | 0.0792 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0173 | 0.0822 | 0.1868 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0075 | 0.0306 | 0.0306 |
Echinococcus multilocularis | cpg binding protein | 0.0026 | 0.005 | 0.0061 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.005 | 0.0113 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0001 | 0.0004 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0114 | 0.0516 | 0.1172 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0101 | 0.0446 | 0.1012 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0051 | 0.0183 | 0.0417 |
Trichomonas vaginalis | esterase, putative | 0.0301 | 0.1493 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0057 | 0.0128 |
Brugia malayi | tailless protein | 0.0024 | 0.0042 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0016 | 0.0034 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0301 | 0.1493 | 0.1493 |
Echinococcus granulosus | muscleblind protein | 0.0137 | 0.0636 | 0.1444 |
Toxoplasma gondii | ABC1 family protein | 0.0301 | 0.1493 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0024 | 0.0042 | 0.0094 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0068 | 0.0453 |
Schistosoma mansoni | tar DNA-binding protein | 0.0855 | 0.4403 | 1 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0049 | 0.0171 | 0.1142 |
Brugia malayi | TAR-binding protein | 0.0855 | 0.4403 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0024 | 0.0043 | 0.0098 |
Brugia malayi | conserved hypotetical protein | 0.0024 | 0.0042 | 0.0094 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0855 | 0.4403 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0136 | 0.063 | 0.4221 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.1493 | 0.3391 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0687 | 0.3525 | 0.8006 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0024 | 0.0042 | 0.005 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0051 | 0.0183 | 0.0417 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0049 | 0.0171 | 0.1142 |
Loa Loa (eye worm) | fatty acid synthase | 0.009 | 0.0387 | 0.0878 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0051 | 0.0183 | 0.0222 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0301 | 0.1493 | 0.3392 |
Onchocerca volvulus | 0.0301 | 0.1493 | 1 | |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0023 | 0.0035 | 0.0235 |
Brugia malayi | hypothetical protein | 0.0241 | 0.118 | 0.2679 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0021 | 0.0024 | 0.0162 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0319 | 0.1592 | 0.3616 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0104 | 0.0237 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0049 | 0.0171 | 0.259 |
Toxoplasma gondii | hypothetical protein | 0.006 | 0.023 | 0.154 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.006 | 0.023 | 0.2773 |
Echinococcus granulosus | FTZ F1 alpha | 0.0051 | 0.0183 | 0.0417 |
Brugia malayi | RNA binding protein | 0.0855 | 0.4403 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.1493 | 0.3391 |
Onchocerca volvulus | 0.0024 | 0.0042 | 0.026 | |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0023 | 0.0035 | 0.0235 |
Brugia malayi | beta-lactamase family protein | 0.0301 | 0.1493 | 0.3392 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0301 | 0.1493 | 0.1493 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0855 | 0.4403 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.013 | 0.0599 | 0.1359 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0024 | 0.0042 | 0.005 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0024 | 0.0042 | 0.0094 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0301 | 0.1493 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0024 | 0.0042 | 0.0094 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0107 | 0.0475 | 0.0475 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.006 | 0.0231 | 0.1534 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0051 | 0.0183 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0301 | 0.1493 | 1 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0022 | 0.0032 | 0.0032 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0051 | 0.0183 | 0.0417 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0151 | 0.0344 |
Brugia malayi | nuclear receptor RXR | 0.0027 | 0.0057 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Plasmodium vivax | mitochondrial import inner membrane translocase subunit TIM23, putative | 0.004 | 0.0125 | 0.0834 |
Schistosoma mansoni | nuclear hormone receptor | 0.0024 | 0.0042 | 0.0094 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0053 | 0.0353 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0101 | 0.0446 | 0.1012 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0687 | 0.3525 | 0.8006 |
Brugia malayi | nuclear receptor NHR-88 | 0.0051 | 0.0183 | 0.0417 |
Loa Loa (eye worm) | acyl carrier protein | 0.0042 | 0.0135 | 0.0305 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0171 | 0.1142 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0785 | 0.1782 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0829 | 0.1883 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 0.5554 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0024 | 0.0042 | 0.0094 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0101 | 0.0446 | 0.1012 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.013 | 0.0599 | 0.1359 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0024 | 0.0042 | 0.005 |
Schistosoma mansoni | cpg binding protein | 0.0026 | 0.005 | 0.0114 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0086 | 0.0578 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 0.1003 |
Schistosoma mansoni | nuclear receptor | 0.0024 | 0.0042 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.1493 | 0.3391 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0241 | 0.118 | 0.2679 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0051 | 0.0183 | 0.0415 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0105 | 0.0703 |
Schistosoma mansoni | nuclear hormone receptor | 0.0051 | 0.0183 | 0.0417 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0024 | 0.0042 | 0.0094 |
Brugia malayi | nuclear hormone receptor | 0.0024 | 0.0042 | 0.0094 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0027 | 0.0057 | 0.0069 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0161 | 0.0365 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0105 | 0.0703 |
Mycobacterium tuberculosis | Conserved protein | 0.0021 | 0.0024 | 0.0024 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0017 | 0.0003 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0446 | 0.1011 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0024 | 0.0042 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0104 | 0.0237 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0039 | 0.0118 | 0.0792 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0021 | 0.0024 | 0.0162 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0151 | 0.0183 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0001 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0151 | 0.0344 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0136 | 0.063 | 0.421 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0057 | 0.0128 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0101 | 0.0446 | 0.0539 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0301 | 0.1493 | 1 |
Brugia malayi | hypothetical protein | 0.0114 | 0.0516 | 0.1172 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.005 | 0.0112 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0091 | 0.0394 | 0.0894 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0161 | 0.1075 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0039 | 0.0118 | 0.0792 |
Echinococcus multilocularis | tar DNA binding protein | 0.0855 | 0.4403 | 0.5324 |
Echinococcus granulosus | tar DNA binding protein | 0.0855 | 0.4403 | 1 |
Brugia malayi | MH2 domain containing protein | 0.013 | 0.0599 | 0.136 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0088 | 0.0379 | 0.0379 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0051 | 0.0183 | 0.0417 |
Onchocerca volvulus | 0.0024 | 0.0042 | 0.026 | |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.006 | 0.023 | 0.154 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0301 | 0.1493 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0051 | 0.0183 | 0.1211 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0001 | 0.0004 |
Echinococcus multilocularis | mitochondrial import inner membrane translocase subunit TIM23, putative | 0.004 | 0.0125 | 0.0151 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0136 | 0.063 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0636 | 0.1443 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0016 | 0.0189 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0105 | 0.0703 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0057 | 0.0128 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0076 | 0.0314 | 0.2086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0114 | 0.0514 | 0.3432 |
Echinococcus multilocularis | geminin | 0.0166 | 0.0785 | 0.0949 |
Mycobacterium tuberculosis | Conserved protein | 0.0301 | 0.1493 | 0.1493 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0151 | 0.0183 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0105 | 0.0703 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0065 | 0.0256 | 0.1712 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0105 | 0.0703 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0021 | 0.0024 | 0.0162 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0049 | 0.0171 | 0.1142 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0046 | 0.0158 | 0.1056 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0023 | 0.0035 | 0.0042 |
Mycobacterium ulcerans | thioesterase | 0.0076 | 0.0314 | 0.2101 |
Brugia malayi | nuclear receptor RXR | 0.0024 | 0.0042 | 0.0094 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0161 | 0.1075 |
Brugia malayi | nuclear hormone receptor | 0.0051 | 0.0183 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0068 | 0.0153 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0051 | 0.0183 | 0.0222 |
Brugia malayi | nuclear receptor NHR-88 | 0.0024 | 0.0042 | 0.0094 |
Brugia malayi | nuclear receptor NHR-67 | 0.0024 | 0.0042 | 0.0094 |
Mycobacterium ulcerans | beta-lactamase | 0.0301 | 0.1493 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0301 | 0.1493 | 0.3391 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0107 | 0.0475 | 0.0475 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0027 | 0.0057 | 0.0129 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0001 | 0.0001 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0137 | 0.0636 | 0.0769 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0016 | 0.0016 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0053 | 0.0353 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0051 | 0.0183 | 0.0222 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0107 | 0.0475 | 0.0475 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.005 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0319 | 0.1592 | 0.3615 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0039 | 0.0118 | 0.0793 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0097 | 0.0423 | 0.2821 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0024 | 0.0042 | 0.0094 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0093 | 0.0402 | 0.0402 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0301 | 0.1493 | 0.3391 |
Schistosoma mansoni | hypothetical protein | 0.0283 | 0.1401 | 0.3181 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0091 | 0.0394 | 0.2636 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.1493 | 0.3391 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0042 | 0.0094 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0051 | 0.0183 | 0.0417 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0023 | 0.0035 | 0.0423 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0023 | 0.0035 | 0.0423 |
Schistosoma mansoni | coup transcription factor | 0.0051 | 0.0183 | 0.0417 |
Brugia malayi | CXXC zinc finger family protein | 0.0024 | 0.0043 | 0.0098 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0023 | 0.0036 | 0.024 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0107 | 0.0475 | 0.0475 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0024 | 0.0042 | 0.0093 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0053 | 0.0354 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0014 | 0.0033 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0052 | 0.0187 | 0.0187 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0027 | 0.0059 | 0.0134 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0016 | 0.0189 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0023 | 0.0035 | 0.008 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0073 | 0.03 | 0.2009 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0098 | 0.0429 | 0.2872 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0049 | 0.0171 | 0.1142 |
Mycobacterium ulcerans | thioesterase TesA | 0.0076 | 0.0314 | 0.2101 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0183 | 0.0415 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0174 | 0.0829 | 0.5554 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0173 | 0.0393 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.006 | 0.0231 | 0.155 |
Giardia lamblia | GTOR | 0.0049 | 0.0171 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0017 | 0.0003 | 0.0003 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0301 | 0.1493 | 0.3392 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0051 | 0.0183 | 0.0417 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0024 | 0.0042 | 0.0094 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0301 | 0.1493 | 1 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0042 | 0.0094 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.001 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.1493 | 0.3391 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0057 | 0.0129 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0051 | 0.0183 | 0.0417 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0023 | 0.0035 | 0.0235 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.005 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0023 | 0.0035 | 0.0235 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0059 | 0.0396 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0024 | 0.0042 | 0.0094 |
Onchocerca volvulus | 0.0024 | 0.0043 | 0.027 | |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0023 | 0.0035 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0057 | 0.0128 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0027 | 0.0057 | 0.0128 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0174 | 0.0829 | 0.5546 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0097 | 0.0423 | 0.2835 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0051 | 0.0183 | 0.1211 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0051 | 0.0183 | 0.0222 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0039 | 0.0118 | 0.0793 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0151 | 0.0344 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0161 | 0.0363 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0017 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 0.5554 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.005 | 0.0333 |
Schistosoma mansoni | cpg binding protein | 0.0026 | 0.005 | 0.0114 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0051 | 0.0183 | 0.0417 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0051 | 0.0183 | 0.0417 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0161 | 0.0363 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0114 | 0.0514 | 0.0514 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0319 | 0.1592 | 0.3615 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0016 | 0.0034 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0042 | 0.0133 | 0.0891 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0091 | 0.0394 | 0.2622 |
Echinococcus multilocularis | muscleblind protein | 0.0137 | 0.0636 | 0.0769 |
Mycobacterium ulcerans | hypothetical protein | 0.0301 | 0.1493 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0028 | 0.0062 | 0.0062 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0037 | 0.0108 | 0.0108 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0023 | 0.0035 | 0.0078 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0051 | 0.0183 | 0.0417 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0174 | 0.0829 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0053 | 0.0354 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0068 | 0.0453 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0151 | 0.0344 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0301 | 0.1493 | 0.1493 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0066 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0173 | 0.0393 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0093 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0051 | 0.0183 | 0.0222 |
Plasmodium vivax | hypothetical protein, conserved | 0.0301 | 0.1493 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0301 | 0.1493 | 0.1493 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0051 | 0.0183 | 0.0415 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0023 | 0.0035 | 0.0235 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 36 % | Inhibition of HIV-1 protease using DABCYL-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS as substrate preincubated at 10 uM for 15 mins before substrate addition measured over 15 mins by fluorometric assay | ChEMBL. | 25042102 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.