Detailed information for compound 924576

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 568.883 | Formula: C15H11Br4N3O
  • H donors: 1 H acceptors: 3 LogP: 5.57 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(c1ccccc1)CCn1nc2c(n1)c(Br)c(c(c2Br)Br)Br
  • InChi: 1S/C15H11Br4N3O/c16-10-11(17)13(19)15-14(12(10)18)20-22(21-15)7-6-9(23)8-4-2-1-3-5-8/h1-5,9,23H,6-7H2
  • InChiKey: MRLZEVIPFNMZQL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.002 0.0105 0.0114
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0714 0.07
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.2901 0.3637
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0796 1
Onchocerca volvulus 0.0017 0.0069 0.0143
Schistosoma mansoni hypothetical protein 0.0562 0.7964 0.7961
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0668 0.9253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0267 0.0735
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0105 0.0096
Brugia malayi nuclear receptor NHR-67 0.0042 0.0427 0.0519
Loa Loa (eye worm) hypothetical protein 0.0016 0.0055 0.006
Giardia lamblia GTOR 0.0046 0.0485 1
Brugia malayi hypoxia-induced factor 1 0.0153 0.2043 0.2551
Echinococcus multilocularis FTZ F1 alpha 0.0088 0.1104 0.1096
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0014 0.0006
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0105 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0086 0.0238
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0055 0.0591
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.01 0.0107
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0485 0.6052
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0069 0.0061
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0113 0.0104
Schistosoma mansoni rab6-interacting 0.002 0.0113 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0485 0.1336
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0097 0.0706
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2321 0.6393
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0349 0.0962
Brugia malayi jmjC domain containing protein 0.0016 0.0053 0.0049
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0055 0.0047
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0034 0.0034
Leishmania major cathepsin L-like protease 0.0017 0.0069 0.0768
Brugia malayi nuclear receptor NHR-88 0.0042 0.0427 0.0519
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0206 0.2768
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0718 0.071
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.3631 1
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0105 0.0096
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0353 0.0344
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0069 0.0055
Echinococcus granulosus jun protein 0.0085 0.1061 0.1053
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2321 0.6393
Brugia malayi jmjC domain containing protein 0.0016 0.0053 0.0049
Entamoeba histolytica hypothetical protein 0.002 0.0105 0.0492
Schistosoma mansoni axis inhibition protein axin 0.002 0.0105 0.0091
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0668 0.9253
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.035 0.4336
Brugia malayi hypothetical protein 0.0037 0.0353 0.0426
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0485 0.5863
Leishmania major importin beta-1 subunit, putative 0.0024 0.0167 0.2012
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0796 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0714 0.0888
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0024
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0718 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0069 0.0061
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0258 0.3558 0.4463
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0069 0.0061
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0055 0.0046
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0053 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Schistosoma mansoni hypothetical protein 0.0069 0.0829 0.0815
Brugia malayi Nuclear hormone receptor E75 0.0042 0.0427 0.0519
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0086 0.0238
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0078 0.0069
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0055 0.0078
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0113 0.0104
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0485 0.0592
Brugia malayi Cathepsin L-like precursor 0.0017 0.0069 0.0069
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.054 0.0526
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2321 0.6393
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0088 0.1104 0.1091
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0247 0.0239
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0044 0.0455
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0042 0.0115
Onchocerca volvulus 0.005 0.0552 0.1285
Brugia malayi nuclear hormone receptor family member nhr-6 0.0042 0.0427 0.0519
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0069 0.0768
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0047
Loa Loa (eye worm) hypothetical protein 0.005 0.0552 0.0685
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Brugia malayi PAS domain containing protein 0.005 0.054 0.0661
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0315 0.0868
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.035 0.4066
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0009 0.5
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0042 0.0427 0.0519
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0086 0.0238
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0069 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0088 0.1104 0.1096
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.022 0.0268
Brugia malayi ecdysteroid receptor 0.0088 0.1104 0.1371
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0315 0.0868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0388 0.1069
Schistosoma mansoni hypothetical protein 0.002 0.0113 0.0099
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.3631 1
Schistosoma mansoni single-minded 0.005 0.054 0.0526
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0485 0.0477
Loa Loa (eye worm) hypothetical protein 0.0083 0.1027 0.1282
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0497 0.0489
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0009 0.0024
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0668 0.066
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0088 0.1104 0.1379
Schistosoma mansoni zinc finger protein 0.0042 0.0427 0.0413
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Toxoplasma gondii exonuclease III APE 0.0019 0.01 0.0693
Echinococcus granulosus flap endonuclease 1 0.0027 0.0206 0.0198
Schistosoma mansoni loxhd1 0.002 0.0113 0.0099
Echinococcus granulosus cathepsin l1 0.0017 0.0069 0.0061
Echinococcus multilocularis thyroid hormone receptor alpha 0.0088 0.1104 0.1096
Loa Loa (eye worm) hypothetical protein 0.0027 0.022 0.0268
Echinococcus granulosus dnaJ subfamily B 0.0416 0.5855 0.5851
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0042 0.0427 0.0989
Plasmodium vivax vivapain-2 0.0017 0.0069 0.0717
Loa Loa (eye worm) hypothetical protein 0.0241 0.331 0.4151
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0167 0.2012
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0053 0.0045
Brugia malayi conserved hypotetical protein 0.0042 0.0427 0.0519
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0044 0.0455
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0078 0.0069
Echinococcus multilocularis fatty acid binding protein FABP2 0.0035 0.0331 0.0323
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0136 0.1214
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0641 0.8843
Brugia malayi hypothetical protein 0.0166 0.2229 0.2786
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.01 0.0733
Brugia malayi nuclear hormone receptor 0.0088 0.1104 0.1371
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0718 1
Echinococcus granulosus RUN 0.002 0.0113 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0105 0.0289
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0055 0.0047
Brugia malayi CXXC zinc finger family protein 0.0029 0.0246 0.0291
Brugia malayi Protein kinase domain containing protein 0.0015 0.0034 0.0025
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0534 0.0653
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0034 0.002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0042 0.0427 0.0419
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0014 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0315 0.0868
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.01 0.1155
Echinococcus granulosus ecdysone induced protein 78C 0.0088 0.1104 0.1096
Schistosoma mansoni nuclear receptor nhr-48 0.0042 0.0427 0.0413
Brugia malayi Cathepsin L-like precursor 0.0017 0.0069 0.0069
Brugia malayi nuclear receptor NHR-88 0.0088 0.1104 0.1371
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0206 0.0198
Loa Loa (eye worm) hypothetical protein 0.0047 0.0499 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0349 0.0962
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0214 0.059
Echinococcus multilocularis GPCR, family 2 0.0016 0.0055 0.0046
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0105 0.0114
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0105 0.0096
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0105 0.0096
Echinococcus multilocularis lamin dm0 0.0027 0.022 0.0211
Loa Loa (eye worm) hypothetical protein 0.0166 0.2229 0.2793
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0349 0.0962
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.2456 0.6763
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0557 0.0692
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0091 0.1148 0.114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0088 0.1104 0.1379
Loa Loa (eye worm) hypothetical protein 0.0051 0.0557 0.0692
Loa Loa (eye worm) hypothetical protein 0.0047 0.0499 0.0619
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0485 0.5863
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0485 0.6052
Schistosoma mansoni hypothetical protein 0.0172 0.2321 0.231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0908 0.09
Brugia malayi RNA, U transporter 1 0.0083 0.1032 0.1279
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0105 0.0114
Entamoeba histolytica hypothetical protein 0.0037 0.0353 0.3904
Schistosoma mansoni hypothetical protein 0.0562 0.7964 0.7961
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0088 0.1104 0.1379
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Schistosoma mansoni rab6-interacting 0.002 0.0113 0.0099
Mycobacterium leprae Possible regulatory protein 0.0013 0.0009 0.5
Brugia malayi orphan nuclear receptor NR2E1 0.0042 0.0427 0.0519
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0105 0.0096
Echinococcus granulosus Ankyrin 0.0015 0.0036 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0218 0.0601
Brugia malayi nuclear hormone receptor family member odr-7 0.0042 0.0427 0.0519
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0088 0.1104 0.1371
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0014 0.0005
Onchocerca volvulus 0.0049 0.0534 0.1242
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0088 0.1104 0.1096
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.1104 0.1096
Brugia malayi nuclear hormone receptor 0.0258 0.3558 0.4458
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.331 0.3304
Entamoeba histolytica hypothetical protein 0.0037 0.0353 0.3904
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0485 0.6052
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0088 0.1104 0.1096
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0427 0.0413
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0485 0.0477
Loa Loa (eye worm) hypothetical protein 0.0017 0.0069 0.0078
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.01 0.067
Brugia malayi Nuclear hormone receptor-like 1 0.0088 0.1104 0.1371
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0088 0.1104 0.1096
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0044 0.0036
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0263 0.3631 0.4549
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Entamoeba histolytica hypothetical protein 0.0037 0.0353 0.3904
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0763 0.9585
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0796 0.0991
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0206 0.23
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0055 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.018 0.0496
Onchocerca volvulus Protein ultraspiracle homolog 0.0088 0.1104 0.2591
Echinococcus granulosus fatty acid binding protein FABP2 0.0035 0.0331 0.0323
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0763 0.9585
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1583 0.1981
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0055 0.0061
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0053 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0272 0.0258
Onchocerca volvulus 0.0027 0.022 0.05
Brugia malayi Death domain containing protein 0.0015 0.0034 0.0025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0557 0.0683
Brugia malayi Cathepsin L-like precursor 0.0017 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.3631 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0718 1
Brugia malayi hypothetical protein 0.0042 0.0427 0.0519
Brugia malayi Pre-SET motif family protein 0.0031 0.0272 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0086 0.0238
Brugia malayi hypothetical protein 0.0042 0.0427 0.0519
Brugia malayi jmjC domain containing protein 0.0062 0.0714 0.088
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0034 0.0061
Schistosoma mansoni RAR-like nuclear receptor 0.0088 0.1104 0.1091
Schistosoma mansoni hypothetical protein 0.0053 0.0585 0.0571
Brugia malayi Nuclear hormone receptor E75 0.0042 0.0427 0.0519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0122
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0088 0.1104 0.1371
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0088 0.1104 0.1371
Brugia malayi Flap endonuclease-1 0.0027 0.0206 0.0241
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Echinococcus multilocularis cysteine protease 0.0017 0.0069 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.018 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0122
Brugia malayi nuclear receptor RXR 0.0047 0.0499 0.061
Echinococcus multilocularis jun protein 0.0085 0.1061 0.1053
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0088 0.1104 0.1096
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.01 0.0419
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0123
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0055 0.0041
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0055 0.0026
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0105 0.0096
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0718 0.9008
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.4362 0.5473
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0053 0.0045
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0069 0.0143
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0272 0.3285
Plasmodium falciparum importin beta, putative 0.0029 0.0247 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0123
Plasmodium falciparum flap endonuclease 1 0.0027 0.0206 0.7876
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0053 0.0045
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0668 0.9253
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0009 0.0024
Onchocerca volvulus 0.0043 0.044 0.102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.018 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0088 0.1104 0.1371
Schistosoma mansoni steroid hormone receptor ad4bp 0.0088 0.1104 0.1091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.018 0.0496
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0105 0.0096
Echinococcus granulosus fatty acid binding protein FABP2 0.0035 0.0331 0.0323
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0009 0.0024
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0499 0.061
Schistosoma mansoni hypothetical protein 0.0015 0.0034 0.002
Schistosoma mansoni ap endonuclease 0.0019 0.01 0.0085
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0069 0.0806
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0055 0.0143
Schistosoma mansoni hypothetical protein 0.0313 0.4362 0.4354
Brugia malayi nuclear receptor RXR 0.0042 0.0427 0.0519
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0105 0.0091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.018 0.0494
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0044 0.003
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0047 0.0499 0.0491
Brugia malayi intermediate filament protein 0.0027 0.022 0.0258
Brugia malayi isocitrate dehydrogenase 0.0016 0.0055 0.0051
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0042 0.0427 0.0419
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Brugia malayi PXA domain containing protein 0.002 0.0105 0.0114
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0009 0.0024
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0206 0.2511
Leishmania major cytochrome p450-like protein 0.0016 0.0056 0.0599
Schistosoma mansoni regulator of G protein signaling 0.002 0.0105 0.0091
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0105 0.0114
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0053 0.0045
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0034 0.0026
Brugia malayi hypothetical protein 0.0125 0.1629 0.2031
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Onchocerca volvulus 0.0067 0.0795 0.186
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0113 0.2726
Brugia malayi PXA domain containing protein 0.002 0.0105 0.0114
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0055 0.006
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0353 0.0339
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0485 0.5723
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.035 0.4336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0055 0.0051
Schistosoma mansoni hypothetical protein 0.0172 0.2321 0.231
Leishmania major hypothetical protein, conserved 0.0016 0.0053 0.057
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0353 0.0426
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.01 0.5
Brugia malayi hypothetical protein 0.0047 0.0499 0.061
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0055 0.0051
Loa Loa (eye worm) hypothetical protein 0.0016 0.0053 0.0059
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0123
Onchocerca volvulus 0.0029 0.0246 0.0561
Loa Loa (eye worm) intermediate filament protein 0.0027 0.022 0.0268
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.2043 0.2558
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0456 0.6435 0.6432
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0053 0.0059
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0105 0.0123
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0105 0.0123
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0123
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.01 0.0274
Echinococcus multilocularis geminin 0.0172 0.2321 0.2315
Schistosoma mansoni cpg binding protein 0.0031 0.027 0.0256
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0113 0.0104
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0105 0.0091
Echinococcus multilocularis snurportin 1 0.0313 0.4362 0.4357
Onchocerca volvulus 0.0042 0.0427 0.0989
Echinococcus multilocularis fatty acid binding protein FABP2 0.0035 0.0331 0.0323
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0497 0.0489
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0088 0.1104 0.1371
Leishmania major cathepsin L-like protease 0.0017 0.0069 0.0768
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0069 0.0078
Brugia malayi jmjC domain containing protein 0.0016 0.0053 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0069 0.0069
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0034 0.0025
Brugia malayi hypothetical protein 0.0067 0.0795 0.0981
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0272 0.0258
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.01 0.2375
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0105 0.0114
Schistosoma mansoni regulator of G protein signaling 0.002 0.0105 0.0091
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0763 0.9585
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0069 0.0806
Schistosoma mansoni hypothetical protein 0.0016 0.0055 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0088 0.1104 0.1371
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0047 0.0499 0.0491
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0056 0.0599
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0796 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0105 0.0123
Plasmodium vivax vivapain-2 0.0017 0.0069 0.0717
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0272 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.018 0.0496
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0105 0.0123
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0056 0.0062
Schistosoma mansoni fatty acid binding protein 0.0035 0.0331 0.0317
Loa Loa (eye worm) hypothetical protein 0.0216 0.2954 0.3703
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.1104 0.1096
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0497 0.0489
Trichomonas vaginalis set domain proteins, putative 0.0242 0.3325 0.9157
Schistosoma mansoni nuclear hormone receptor 0.0088 0.1104 0.1091
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0053 0.0045
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0123
Schistosoma mansoni nuclear receptor 0.0042 0.0427 0.0413
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0206 0.0251
Schistosoma mansoni regulator of G protein signaling 0.002 0.0105 0.0091
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0036 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0497 0.0607
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0214 0.059
Toxoplasma gondii cathepsin CPL 0.0017 0.0069 0.0235
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0105 0.0096
Loa Loa (eye worm) hypothetical protein 0.0016 0.0053 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0315 0.0868
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0105 0.0096
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0562 0.7964 0.7963
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.3631 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0122
Plasmodium vivax SET domain protein, putative 0.0031 0.0272 1
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.2321 0.5471
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0053 0.012
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0167 0.046
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0055 0.0051
Echinococcus granulosus Nuclear hormone receptor HR96 0.0042 0.0427 0.0419
Onchocerca volvulus 0.0017 0.0069 0.0143
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0056 0.0599
Brugia malayi Doublecortin family protein 0.002 0.0113 0.0124
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.069 0.0682
Echinococcus multilocularis dnaJ subfamily B 0.0416 0.5855 0.5851
Echinococcus multilocularis tumor protein p63 0.0344 0.4806 0.4801
Entamoeba histolytica hypothetical protein 0.002 0.0105 0.0492
Echinococcus granulosus lamin dm0 0.0027 0.022 0.0211
Onchocerca volvulus 0.0037 0.0353 0.0815
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0047
Onchocerca volvulus 0.0088 0.1104 0.2591
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Schistosoma mansoni lamin 0.0027 0.022 0.0206
Brugia malayi Pre-SET motif family protein 0.0212 0.2901 0.3631
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0247 0.2702
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.01 0.1155
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0796 0.0788
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0047
Echinococcus multilocularis expressed protein 0.038 0.5327 0.5323
Leishmania major cathepsin L-like protease 0.0017 0.0069 0.0768
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0208 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Schistosoma mansoni coup transcription factor 0.0088 0.1104 0.1091
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0069 0.0061
Schistosoma mansoni axis inhibition protein axin 0.002 0.0105 0.0091
Brugia malayi M-phase phosphoprotein, mpp8 0.0103 0.1316 0.1637
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0047 0.0499 0.0486
Onchocerca volvulus 0.0017 0.0069 0.0143
Schistosoma mansoni jun-related protein 0.0069 0.0829 0.0815
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0053 0.0045
Loa Loa (eye worm) nuclear hormone receptor 0.0042 0.0427 0.0528
Schistosoma mansoni survival motor neuron protein 0.0049 0.0534 0.052
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0034 0.0026
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0427 0.0413
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0053 0.0039
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0353 0.0344
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0055 0.0088
Brugia malayi Cathepsin L-like precursor 0.0017 0.0069 0.0069
Echinococcus granulosus importin subunit beta 1 0.0029 0.0247 0.0239
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0497 0.0616
Brugia malayi steroid hormone receptor 0.0088 0.1104 0.1371
Leishmania major cathepsin L-like protease 0.0017 0.0069 0.0768
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0053 0.057
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0499 0.061
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0105 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.0499 0.0619
Schistosoma mansoni regulator of G protein signaling 0.002 0.0105 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0349 0.0962
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.01 0.1155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.331 0.3304
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0086 0.0238
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0557 0.0683
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0034
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0105 0.0096
Loa Loa (eye worm) ctsf protein 0.0017 0.0069 0.0078
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0113 0.3067
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0088 0.1104 0.1096
Entamoeba histolytica hypothetical protein 0.002 0.0105 0.0492
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0053 0.057
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0044 0.0038
Schistosoma mansoni cpg binding protein 0.0031 0.027 0.0256
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0042 0.0427 0.0419
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Brugia malayi hypothetical protein 0.0241 0.331 0.4145
Echinococcus granulosus single minded 2 0.0037 0.0353 0.0345
Schistosoma mansoni regulator of G protein signaling 0.002 0.0105 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0349 0.0962
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Brugia malayi hypothetical protein 0.002 0.0113 0.0124
Onchocerca volvulus 0.0103 0.1316 0.3093
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0386 0.0377
Brugia malayi hypothetical protein 0.002 0.0105 0.0114
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0055 0.0591
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0167 0.046
Schistosoma mansoni hypothetical protein 0.0037 0.0353 0.0339
Brugia malayi tailless protein 0.0042 0.0427 0.0519
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0105 0.0096
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0044 0.0455
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0085 0.1061 0.1053
Schistosoma mansoni thyroid hormone receptor 0.0088 0.1104 0.1091
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0718 0.0704
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0044 0.0036
Entamoeba histolytica hypothetical protein 0.0024 0.0167 0.1347
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0315 0.0868
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0047 0.0499 0.0619
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0105 0.0096
Loa Loa (eye worm) hypothetical protein 0.0125 0.1629 0.2039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Schistosoma mansoni jumonji domain containing protein 0.006 0.069 0.0676
Schistosoma mansoni ap endonuclease 0.0019 0.01 0.0085
Schistosoma mansoni netrin receptor unc5 0.0015 0.0034 0.002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0105 0.0289
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0105 0.0096
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.01 0.5
Echinococcus multilocularis cpg binding protein 0.0031 0.027 0.0261
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0044 0.0047
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0353 0.4493
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0055 0.0046
Schistosoma mansoni importin beta-1 0.0029 0.0247 0.0233
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0053 0.0039
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0056 0.0062
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0105 0.0096
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0562 0.7026
Brugia malayi SET domain containing protein 0.0013 0.0016 0.0002
Brugia malayi Importin beta-1 subunit 0.0029 0.0247 0.0293
Brugia malayi ecdysone receptor 0.0042 0.0427 0.0519
Loa Loa (eye worm) fibroinase 0.0017 0.0069 0.0078
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0105 0.0096
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0053 0.0045
Echinococcus granulosus FTZ F1 alpha 0.0088 0.1104 0.1096
Echinococcus granulosus snurportin 1 0.0313 0.4362 0.4357
Schistosoma mansoni hypothetical protein 0.0016 0.0055 0.004
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0718 0.0704
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0014 0.0006
Onchocerca volvulus 0.0103 0.1316 0.3093
Loa Loa (eye worm) nuclear receptor NHR-67 0.0042 0.0427 0.0528
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0246 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0105 0.0091
Loa Loa (eye worm) cysteine protease 0.0017 0.0069 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0252 0.0695
Loa Loa (eye worm) hypothetical protein 0.002 0.0113 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.018 0.0496
Loa Loa (eye worm) hypothetical protein 0.0035 0.0325 0.04
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0055 0.0026
Echinococcus multilocularis musashi 0.0027 0.022 0.0211
Onchocerca volvulus 0.0027 0.022 0.05
Schistosoma mansoni microtubule-associated protein tau 0.0702 1 1
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0105 0.0091
Brugia malayi jmjC domain containing protein 0.006 0.069 0.0849
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0088 0.1104 0.1091
Brugia malayi MH2 domain containing protein 0.0121 0.1583 0.1973
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0315 0.0868
Echinococcus granulosus geminin 0.0172 0.2321 0.2315
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.01 0.0661
Schistosoma mansoni hypothetical protein 0.0035 0.0325 0.0311
Echinococcus granulosus tumor protein p63 0.0344 0.4806 0.4801
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0088 0.1104 0.1379
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0353 0.0345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.01 0.0091
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0088 0.1104 0.1091
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0668 0.066
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0069 0.019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0088 0.1104 0.1371
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0636 0.0628
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0086 0.0238
Echinococcus granulosus phd:f box containing protein 0.0016 0.0053 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0088 0.1104 0.1371
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0053 0.0039
Loa Loa (eye worm) steroid hormone receptor 0.0088 0.1104 0.1379
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0485 0.0601
Echinococcus multilocularis lamin 0.0027 0.022 0.0211
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0056 0.0062
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0206 0.7001
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0105 0.0114
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.1148 0.1135
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0042 0.0427 0.0413
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0088 0.1104 0.1371
Brugia malayi hypothetical protein 0.002 0.0113 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0024
Leishmania major cathepsin L-like protease 0.0065 0.0763 0.9585
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2321 0.6393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Schistosoma mansoni fatty acid binding protein 0.0035 0.0331 0.0317
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1583 0.1981
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.01 0.0116
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0009 0.0024
Echinococcus granulosus death domain containing protein 0.0015 0.0034 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0272 0.0263
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0247 0.0302
Schistosoma mansoni retinoic acid receptor RXR 0.0456 0.6435 0.643
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0105 0.0289
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0069 0.0768
Echinococcus granulosus lamin 0.0027 0.022 0.0211
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0714 0.0706
Echinococcus granulosus Nuclear hormone receptor HR96 0.0042 0.0427 0.0419
Schistosoma mansoni intermediate filament proteins 0.0027 0.022 0.0206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Brugia malayi Cytochrome P450 family protein 0.0016 0.0056 0.0052
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0718 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.044 0.0426
Brugia malayi Cytochrome P450 family protein 0.0016 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0213 0.0259
Schistosoma mansoni lipoxygenase 0.0056 0.0636 0.0623
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0105 0.0289
Brugia malayi Cathepsin L-like precursor 0.0017 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0485 0.1336
Onchocerca volvulus Huntingtin homolog 0.0125 0.1629 0.3833
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.1104 0.1096
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0055 0.0591
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.1104 0.1096
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0272 0.0263
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0105 0.0091
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0763 0.9585
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0427 0.0419
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0088 0.1104 0.1379
Schistosoma mansoni cpg binding protein 0.0029 0.0246 0.0232
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0069 0.0061
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0562 0.7964 1
Leishmania major cathepsin L-like protease 0.0065 0.0763 0.9585
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0042 0.0427 0.0989
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0113 0.0104
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0796 0.0782
Onchocerca volvulus 0.002 0.0113 0.0247
Schistosoma mansoni lipoxygenase 0.002 0.0113 0.0099
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0044 0.0455
Loa Loa (eye worm) RGS-3 protein 0.002 0.0105 0.0123
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0796 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0305 0.4236 1
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0113 0.0104
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0206 0.2511
Schistosoma mansoni hypothetical protein 0.0416 0.5855 0.5849
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0047
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.1148 0.1135
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0055 0.0046
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0796 0.0983
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0737 0.0723
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.041 0.5758 0.5754
Echinococcus granulosus GPCR family 2 0.0016 0.0055 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2321 0.6393
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0714 0.07
Echinococcus multilocularis Ankyrin 0.0015 0.0036 0.0027
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0014 0.0005
Loa Loa (eye worm) hypothetical protein 0.0103 0.1318 0.1647
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0562 0.7964 0.7963
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0009 0.0024
Brugia malayi Cathepsin L-like precursor 0.0017 0.0069 0.0069
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0034 0.0026
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0035 0.0036
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0088 0.1104 0.1091
Schistosoma mansoni hypothetical protein 0.0016 0.0055 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0218 0.0601
Leishmania major cathepsin L-like protease 0.0017 0.0069 0.0768
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0206 0.2154
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0796 0.0788
Brugia malayi jmjC domain containing protein 0.0016 0.0053 0.0049
Echinococcus multilocularis RUN 0.002 0.0113 0.0104
Schistosoma mansoni lamin 0.0027 0.022 0.0206
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0263 0.3631 0.4554
Brugia malayi Steroid receptor seven-up type 2 0.0088 0.1104 0.1371
Onchocerca volvulus 0.0017 0.0069 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0122
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0069 0.0061
Echinococcus granulosus thyroid hormone receptor alpha 0.0042 0.0427 0.0419
Schistosoma mansoni hypothetical protein 0.0049 0.0534 0.052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0386 0.0377
Loa Loa (eye worm) hypothetical protein 0.0016 0.0053 0.0059
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0035 0.0096
Loa Loa (eye worm) DR-78 0.0042 0.0427 0.0528
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0053 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0497 0.0483
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Onchocerca volvulus Bile acid receptor homolog 0.0088 0.1104 0.2591
Plasmodium vivax importin-beta 2, putative 0.0029 0.0247 0.8889
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0718 0.071
Echinococcus multilocularis microtubule associated protein 2 0.0702 1 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0088 0.1104 0.1091
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0497 0.0483
Onchocerca volvulus 0.0042 0.0427 0.0989
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0105 0.0096
Loa Loa (eye worm) hypothetical protein 0.0047 0.0499 0.0619
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0427 0.0419
Brugia malayi Uncoordinated protein 44 0.0015 0.0034 0.0025
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.01 0.2111
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0485 0.5723
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0611 0.076
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0497 0.0489
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.3631 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0272 0.0263
Schistosoma mansoni polycystin 1-related 0.002 0.0113 0.0099
Loa Loa (eye worm) doublecortin family protein 0.002 0.0113 0.0133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0035 0.0026
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0069 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0105 0.0289
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0088 0.1104 0.1091
Leishmania major cathepsin L-like protease 0.0065 0.0763 0.9585
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0105 0.0091
Onchocerca volvulus 0.0242 0.3327 0.785
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0086 0.0238
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.022 0.0258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0069 0.019
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0088 0.1104 0.1371
Brugia malayi hypothetical protein 0.0103 0.1318 0.1639
Loa Loa (eye worm) hypothetical protein 0.0031 0.0272 0.0333
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0325 0.039
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0055 0.0143
Entamoeba histolytica hypothetical protein 0.0037 0.0353 0.3904
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0056 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0069 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.3631 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0668 0.0655
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.01 0.0091
Schistosoma mansoni flap endonuclease-1 0.0024 0.0169 0.0155
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.069 0.0682
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2321 0.6393
Schistosoma mansoni thyroid hormone receptor 0.0088 0.1104 0.1091
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0497 0.0483
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Onchocerca volvulus 0.0017 0.0069 0.0143
Echinococcus multilocularis ecdysone induced protein 78C 0.0088 0.1104 0.1096
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0908 0.09
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.01 0.0274
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0668 0.838
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Echinococcus granulosus cpg binding protein 0.0031 0.027 0.0261
Loa Loa (eye worm) hypothetical protein 0.0103 0.1316 0.1645
Loa Loa (eye worm) hypothetical protein 0.002 0.0113 0.0133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0763 0.9565
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0105 0.0289
Onchocerca volvulus 0.0017 0.0069 0.0143
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0069 0.0806
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0009 0.0024
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0485 0.0471
Brugia malayi indoleamine 2,3-dioxygenase 0.0562 0.7964 1
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0206 0.1887
Onchocerca volvulus 0.0017 0.0069 0.0143
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.069 0.0682
Echinococcus granulosus nuclear receptor nhr 48 0.0042 0.0427 0.0419
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0796 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0085 0.1061 0.1053
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2321 0.6393
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0105 0.0091
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0035 0.0331 0.0398
Brugia malayi photoreceptor-specific nuclear receptor 0.0088 0.1104 0.1371
Echinococcus multilocularis cysteine protease 0.0017 0.0069 0.0061
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0069 0.0143
Echinococcus granulosus expressed protein 0.038 0.5327 0.5323
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0167 0.046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0088 0.1104 0.1379
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0681 0.8547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0485 0.1336
Brugia malayi Cytochrome P450 family protein 0.0027 0.0208 0.0243
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0246 0.03
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0088 0.1104 0.1371
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0091 0.1148 0.114
Schistosoma mansoni hypothetical protein 0.0016 0.0055 0.004
Echinococcus granulosus axis inhibition protein axin 0.002 0.0105 0.0096
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0315 0.3939
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0485 0.6052
Onchocerca volvulus 0.002 0.0113 0.0247
Loa Loa (eye worm) hypothetical protein 0.0125 0.1629 0.2039
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0042 0.0427 0.0413
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0069 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0042 0.0115
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0247 0.292
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0636 0.0628
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0113 0.0104
Echinococcus granulosus axis inhibition protein axin 0.002 0.0105 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0088 0.1104 0.1379
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0042 0.0427 0.0419
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0088 0.1104 0.1371
Brugia malayi bZIP transcription factor family protein 0.0085 0.1061 0.1316
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0718 1
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0053 0.0039
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0034 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.1104 0.1379
Loa Loa (eye worm) hypothetical protein 0.0047 0.0499 0.0619
Onchocerca volvulus Huntingtin homolog 0.0125 0.1629 0.3833
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0315 0.0868
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.2456 0.6763
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0009 0.0002
Brugia malayi hypothetical protein 0.0047 0.0499 0.061
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0088 0.1104 0.1096
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0206 0.0568
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0218 0.0601
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0088 0.1104 0.1096
Loa Loa (eye worm) hypothetical protein 0.0042 0.0427 0.0528
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0552 0.0538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0122
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0668 0.0822
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0088 0.1104 0.1371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0069 0.019
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0035 0.0331 0.0407
Schistosoma mansoni nuclear receptor 0.0042 0.0427 0.0413
Echinococcus multilocularis nuclear receptor nhr 48 0.0042 0.0427 0.0419
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0247 0.2702
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0086 0.0238
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0499 0.0486
Echinococcus granulosus intermediate filament protein 0.0027 0.022 0.0211
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0105 0.0114
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0009 0.0024

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 31.09 % Inhibition of human CK2alpha using RRRDDDSDDD peptide substrate at 200 uM by P81 filter-binding assay ChEMBL. 25036794
Activity (binding) = 93 % Inhibition of human CK2alpha using RRRDDDSDDD peptide substrate at 20 uM by P81 filter-binding assay ChEMBL. 25036794
Activity (functional) = 115 % Anticancer activity against human MCF7 cells assessed as cell viability at 12.5 uM after 24 hrs by MTT assay ChEMBL. 25036794

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.