Detailed information for compound 926995

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 785.879 | Formula: C43H51N3O11
  • H donors: 5 H acceptors: 8 LogP: 7.44 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 2
  • SMILES: CO[C@H]1/C=C/O[C@]2(C)Oc3c(C2=O)c2c(c(c3C)O)c(O)c(c3c2nc2n3ccc(c2)C)NC(=O)/C(=C\C=C\[C@@H]([C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@H]1C)OC(=O)C)C)O)C)O)C)/C
  • InChi: 1S/C43H51N3O11/c1-19-14-16-46-28(18-19)44-32-29-30-37(50)25(7)40-31(29)41(52)43(9,57-40)55-17-15-27(54-10)22(4)39(56-26(8)47)24(6)36(49)23(5)35(48)20(2)12-11-13-21(3)42(53)45-33(34(32)46)38(30)51/h11-18,20,22-24,27,35-36,39,48-51H,1-10H3,(H,45,53)/b12-11+,17-15+,21-13-/t20-,22-,23+,24-,27-,35-,36+,39+,43+/m0/s1
  • InChiKey: NZCRJKRKKOLAOJ-ZXYFGDMBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0069 0.0139 0.2402
Loa Loa (eye worm) hypothetical protein 0.0655 0.1892 0.2829
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0046 0.0073 0.0137
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0046 0.0073 0.0087
Schistosoma mansoni hypothetical protein 0.0058 0.0107 0.0129
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0118 0.0343
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0139 0.1386
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0069 0.0139 0.0364
Echinococcus multilocularis pyruvate kinase 0.0026 0.0012 0.0014
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.1015 0.2968 0.2945
Entamoeba histolytica hypothetical protein 0.0178 0.0464 0.4684
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Echinococcus granulosus heat shock protein 90 0.0079 0.017 0.0204
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0277 0.0761 0.7699
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0059 0.0088
Echinococcus granulosus glycoprotein Antigen 5 0.0204 0.0543 0.0653
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0058 0.0107 0.0128
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0064 0.0162
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Treponema pallidum heat shock protein 90 0.007 0.0142 0.0324
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0172 0.0207
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0017 0.002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.005 0.0082 0.1106
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0073 0.0903
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.008 0.0162
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0064 0.0156
Echinococcus granulosus GTP binding nuclear protein Ran 0.009 0.0203 0.0244
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0543 0.0653
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Brugia malayi Trypsin family protein 0.0204 0.0543 0.1318
Onchocerca volvulus 0.0058 0.0107 0.0403
Entamoeba histolytica hexokinase 1 0.0088 0.0195 0.1957
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.0137
Brugia malayi Cytochrome P450 family protein 0.0129 0.0318 0.0773
Leishmania major hypothetical protein, conserved 0.0046 0.0073 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0113 0.0328
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0152 0.0183
Schistosoma mansoni opsin-like receptor 0.0028 0.0017 0.002
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.006 0.0113 0.1512
Trypanosoma cruzi cytochrome P450, putative 0.0129 0.0318 0.6436
Mycobacterium ulcerans short chain dehydrogenase 0.3369 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0425 0.1385
Schistosoma mansoni ran 0.009 0.0203 0.0244
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Loa Loa (eye worm) hypothetical protein 0.0204 0.0543 0.0812
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Schistosoma mansoni hexokinase 0.0088 0.0195 0.0235
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Loa Loa (eye worm) hypothetical protein 0.0053 0.0092 0.0138
Echinococcus granulosus snurportin 1 0.2261 0.6688 0.8034
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0277 0.0761 0.0915
Schistosoma mansoni alpha-glucosidase 0.0169 0.044 0.0528
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0059 0.0143
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Trichomonas vaginalis importin beta-1, putative 0.0172 0.0447 0.1458
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1402 0.4122 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.005 0.0082 0.0049
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0046 0.0073 0.004
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0142 0.0213
Schistosoma mansoni hypothetical protein 0.157 0.4626 0.5557
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0051 0.0086 0.1206
Toxoplasma gondii Hsp90 domain-containing protein 0.0189 0.0498 0.1585
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.0687 0.1027
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Echinococcus multilocularis translational activator gcn1 0.004 0.0053 0.0064
Schistosoma mansoni dihydropteridine reductase 0.0069 0.0139 0.0167
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0017 0.002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.0522 0.0627
Echinococcus multilocularis serotonin receptor 0.0028 0.0017 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Plasmodium vivax heat shock protein, putative 0.0189 0.0498 0.1585
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0017 0.0025
Brugia malayi G-protein coupled receptor 0.0028 0.0017 0.0041
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0146 0.0114
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0065
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Brugia malayi Importin beta-1 subunit 0.0212 0.0566 0.1374
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0017 0.002
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.005 0.0082 0.0049
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0017 0.0041
Brugia malayi Trypsin family protein 0.0303 0.084 0.2039
Schistosoma mansoni hypothetical protein 0.0204 0.0543 0.0653
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Echinococcus multilocularis replication factor c subunit 1 0.006 0.0113 0.0136
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Brugia malayi beta-lactamase 0.0035 0.0038 0.0092
Schistosoma mansoni hypothetical protein 0.015 0.0383 0.046
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0146 0.0385
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0017 0.002
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0069 0.0139 0.0107
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0017 0.002
Brugia malayi hypothetical protein 0.0178 0.0464 0.1126
Schistosoma mansoni alpha glucosidase 0.0044 0.0064 0.0077
Plasmodium vivax ataxin-2 like protein, putative 0.0182 0.0477 0.1514
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.009 0.0203 0.3832
Entamoeba histolytica hypothetical protein 0.0178 0.0464 0.4684
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0033 0.0049
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0046 0.0073 0.0903
Mycobacterium ulcerans oxidoreductase 0.0046 0.0073 0.004
Brugia malayi ecdysteroid receptor 0.0042 0.0059 0.0143
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0348 0.0418
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0038 0.0006
Brugia malayi Hexokinase family protein 0.0088 0.0195 0.0474
Loa Loa (eye worm) hypothetical protein 0.0234 0.0634 0.0948
Onchocerca volvulus 0.0058 0.0107 0.0403
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0384 0.0462
Onchocerca volvulus 0.0031 0.0025 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0146 0.0353
Echinococcus granulosus dnaJ subfamily B 0.0413 0.1168 0.1403
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0092 0.006
Loa Loa (eye worm) hypothetical protein 0.0303 0.084 0.1257
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0054 0.0074
Trypanosoma brucei oxidoreductase-like protein 0.0115 0.0278 0.46
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0046 0.0073 0.004
Onchocerca volvulus Huntingtin homolog 0.0121 0.0296 0.1252
Mycobacterium leprae putative cytochrome p450 0.005 0.0082 0.0167
Brugia malayi Pax transcription factor protein 2 0.0243 0.066 0.16
Echinococcus multilocularis tissue type plasminogen activator 0.0058 0.0107 0.0129
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0113 0.0328
Loa Loa (eye worm) hypothetical protein 0.0121 0.0296 0.0443
Onchocerca volvulus 0.0069 0.0139 0.0548
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0046 0.0073 0.0903
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Trypanosoma brucei hexokinase, putative 0.0088 0.0195 0.3052
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Brugia malayi kap beta 3 protein 0.004 0.0053 0.013
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0058 0.0107 0.0259
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Echinococcus multilocularis hexokinase 0.0088 0.0195 0.0235
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Plasmodium vivax transportin, putative 0.004 0.0053 0.0071
Loa Loa (eye worm) hexokinase 0.0088 0.0195 0.0292
Loa Loa (eye worm) hypothetical protein 0.01 0.0233 0.0348
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0046 0.0073 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0683 0.2258
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0028 0.0017 0.0025
Echinococcus granulosus protein tyrosine phosphatase n9 0.0058 0.0107 0.0128
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus multilocularis conserved hypothetical protein 0.0046 0.0073 0.0087
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0046 0.0073 0.0087
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0017 0.0025
Onchocerca volvulus 0.0204 0.0543 0.2356
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0038 0.0046
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.0051
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0073 0.0903
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.009 0.0203 0.3189
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Echinococcus multilocularis importin 5 0.004 0.0053 0.0064
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0059 0.0088
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0046 0.0073 0.025
Brugia malayi beta-lactamase family protein 0.0035 0.0038 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0425 0.1385
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0038 0.0104
Schistosoma mansoni cpg binding protein 0.0031 0.0025 0.003
Brugia malayi neuropeptide F receptor 0.0028 0.0017 0.0041
Mycobacterium ulcerans dehydrogenase/reductase 0.0046 0.0073 0.004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0064 0.0625
Schistosoma mansoni carbonyl reductase 0.0046 0.0073 0.0087
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Brugia malayi Kringle domain containing protein 0.0058 0.0107 0.026
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0017 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0115 0.0278 0.0246
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0073 0.0903
Brugia malayi HSF-type DNA-binding domain containing protein 0.01 0.0233 0.0565
Schistosoma mansoni neuropeptide receptor 0.0028 0.0017 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0038 0.0045
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Brugia malayi hypothetical protein 0.0058 0.0107 0.0259
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0058 0.0107 0.0259
Loa Loa (eye worm) hypothetical protein 0.0204 0.0543 0.0812
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.1402 0.4122 0.4952
Schistosoma mansoni hypothetical protein 0.0028 0.0017 0.002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0043 0.0037
Toxoplasma gondii heat shock protein HSP90 0.0079 0.017 0.0468
Mycobacterium tuberculosis Possible oxidoreductase 0.0069 0.0139 0.0107
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0046 0.0073 0.0087
Leishmania major hypothetical protein, conserved 0.0046 0.0073 0.0903
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0038 0.0019
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0046 0.0073 0.0903
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0017 0.002
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0172 0.0207
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0118 0.1915
Schistosoma mansoni importin-beta 2 0.004 0.0053 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0118 0.0343
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.0449 0.0418
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus granulosus muscleblind protein 0.0151 0.0384 0.0462
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0044 0.0066 0.0079
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0017 0.002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0051 0.0086 0.0103
Loa Loa (eye worm) hypothetical protein 0.006 0.0113 0.0169
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Brugia malayi hypothetical protein 0.006 0.0113 0.0275
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.005 0.0082 0.0049
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.005 0.0082 0.0049
Schistosoma mansoni biogenic amine receptor 0.0028 0.0017 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Echinococcus granulosus neuropeptide receptor 0.0028 0.0017 0.002
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0046 0.0073 0.0752
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.009 0.0203 0.0303
Trypanosoma cruzi heat shock protein 90, putative 0.0066 0.013 0.2196
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0277 0.0761 0.0915
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0046 0.0073 0.0087
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0172 0.2611
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0017 0.0025
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0118 0.0343
Leishmania major short chain dehydrogenase, putative 0.0046 0.0073 0.0903
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0425 0.1829
Echinococcus granulosus replication factor c subunit 1 0.006 0.0113 0.0136
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.005 0.0082 0.092
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0058 0.0107 0.0128
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0069 0.0139 0.0364
Onchocerca volvulus 0.0058 0.0107 0.0403
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0072 0.0086
Echinococcus multilocularis steroid dehydrogenase 0.0046 0.0073 0.0087
Echinococcus granulosus WW domain containing oxidoreductase 0.0046 0.0073 0.0087
Echinococcus multilocularis neuropeptide receptor A26 0.0493 0.1406 0.1688
Echinococcus multilocularis GPCR, family 2 0.015 0.0383 0.046
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Mycobacterium ulcerans short-chain type oxidoreductase 0.0046 0.0073 0.004
Onchocerca volvulus 0.0058 0.0107 0.0403
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0073 0.0903
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0082 0.0177 0.0213
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0543 0.0653
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.005 0.0082 0.0049
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.006 0.0113 0.014
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0059 0.0143
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0057
Schistosoma mansoni gabp alpha 0.0073 0.0152 0.0183
Schistosoma mansoni protein tyrosine phosphatase 0.0058 0.0107 0.0128
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0017 0.002
Schistosoma mansoni neuropeptide receptor 0.0128 0.0318 0.0382
Brugia malayi cytochrome P450 0.005 0.0082 0.0198
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0017 0.002
Trypanosoma brucei transcription factor BTF3, putative 0.0042 0.006 0.0513
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Leishmania major hexokinase, putative 0.0088 0.0195 0.3667
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0058 0.0107 0.0128
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0086 0.0236
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.0348 0.052
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.005 0.0082 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Mycobacterium tuberculosis Probable oxidoreductase 0.0115 0.0278 0.0246
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0113 0.1817
Loa Loa (eye worm) protein tyrosine phosphatase 0.0058 0.0107 0.016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.0049
Echinococcus multilocularis Mastin 0.0204 0.0543 0.0653
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Trichomonas vaginalis heat shock protein, putative 0.007 0.0142 0.0424
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0059 0.0143
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0017 0.002
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.005 0.0082 0.0049
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0038 0.0006
Brugia malayi Heterochromatin protein 1 0.007 0.0142 0.0345
Toxoplasma gondii heat shock protein 75, putative 0.0044 0.0066 0.0113
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0425 0.1385
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1402 0.4122 0.4952
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.0522 0.078
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Mycobacterium leprae Probable lipase LipE 0.0035 0.0038 0.0019
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.008 0.0096
Echinococcus multilocularis importin subunit beta 1 0.0212 0.0566 0.068
Schistosoma mansoni carbonyl reductase 0.0046 0.0073 0.0087
Loa Loa (eye worm) hypothetical protein 0.0071 0.0146 0.0218
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0051 0.0086 0.0103
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0058 0.0107 0.0128
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Toxoplasma gondii LsmAD domain-containing protein 0.0182 0.0477 0.1514
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0059 0.0143
Leishmania major hypothetical protein, conserved 0.004 0.0053 0.0471
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0475 0.1354 0.2024
Brugia malayi Ets-domain containing protein 0.0073 0.0152 0.0369
Schistosoma mansoni hypothetical protein 0.157 0.4626 0.5557
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0118 0.0176
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0017 0.002
Onchocerca volvulus 0.0058 0.0107 0.0405
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0017 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0146 0.0114
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0017 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.0077 0.0093
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0017 0.0041
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0092 0.0203
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0017 0.002
Onchocerca volvulus 0.0058 0.0107 0.0403
Toxoplasma gondii ATPase, AAA family protein 0.006 0.0113 0.0275
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.005 0.0082 0.0049
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0172 0.0447 0.1458
Onchocerca volvulus Heat shock factor protein 2 homolog 0.01 0.0233 0.0967
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.009 0.0203 0.058
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0073 0.071
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0017 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0425 0.1385
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0059 0.0071
Toxoplasma gondii kringle domain-containing protein 0.0058 0.0107 0.0254
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0059 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0017 0.002
Brugia malayi hypothetical protein 0.0234 0.0634 0.1537
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0058 0.0107 0.0128
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0146 0.0114
Entamoeba histolytica heat shock transcription factor, putative 0.01 0.0233 0.2336
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0038
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.008 0.012
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Schistosoma mansoni hypothetical protein 0.015 0.0383 0.046
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.008 0.1071
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.006 0.0113 0.0328
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0151 0.0384 0.0575
Brugia malayi CXXC zinc finger family protein 0.0029 0.002 0.005
Brugia malayi G protein-coupled receptor 0.0028 0.0017 0.0041
Plasmodium vivax replication factor C subunit 1, putative 0.006 0.0113 0.0275
Loa Loa (eye worm) hypothetical protein 0.0212 0.0566 0.0847
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Schistosoma mansoni transcription factor LCR-F1 0.0178 0.0464 0.0558
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0059 0.0071
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0059 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0059 0.0088
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0683 0.2258
Leishmania major GTP-binding protein, putative 0.009 0.0203 0.3832
Echinococcus granulosus endoplasmin 0.007 0.0142 0.017
Echinococcus granulosus translational activator gcn1 0.004 0.0053 0.0064
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0543 0.0653
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Echinococcus granulosus serotonin receptor 0.0028 0.0017 0.002
Schistosoma mansoni microtubule-associated protein tau 0.2809 0.8325 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0146 0.0114
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Brugia malayi G-protein coupled receptor 0.0028 0.0017 0.0041
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0017 0.002
Onchocerca volvulus 0.006 0.0113 0.0432
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0063 0.0121 0.018
Toxoplasma gondii NAC domain-containing protein 0.0042 0.006 0.0093
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0683 0.2258
Echinococcus granulosus retinol dehydrogenase 11 0.0046 0.0073 0.0087
Trypanosoma cruzi Heat shock protein 83, putative 0.0079 0.017 0.3095
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0073 0.0752
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0043 0.0052
Echinococcus granulosus nibrin 0.006 0.0113 0.0136
Echinococcus multilocularis retinol dehydrogenase 13 0.0046 0.0073 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.005 0.0082 0.0049
Trypanosoma cruzi hexokinase, putative 0.0088 0.0195 0.3667
Brugia malayi Ets-domain containing protein 0.0073 0.0152 0.0369
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0059 0.0071
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0003 0.0004
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0137
Brugia malayi Cytochrome P450 family protein 0.0144 0.0363 0.0881
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0017 0.002
Brugia malayi oxidoreductase 0.0046 0.0073 0.0176
Echinococcus granulosus heat shock protein 90 0.0066 0.013 0.0156
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.006 0.0147
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0059 0.0071
Plasmodium falciparum replication factor C subunit 1, putative 0.006 0.0113 0.0275
Onchocerca volvulus 0.0058 0.0107 0.0403
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0059 0.0143
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0146 0.0353
Trichomonas vaginalis ran, putative 0.009 0.0203 0.0631
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0277 0.0761 0.0915
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Trypanosoma cruzi short chain dehydrogenase, putative 0.0046 0.0073 0.0903
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0004
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0167 0.0432 0.0518
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0051 0.0086 0.1206
Echinococcus multilocularis heat shock protein 90 0.0066 0.013 0.0156
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0046 0.0073 0.0903
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0046 0.0073 0.004
Echinococcus multilocularis pyruvate kinase 0.0033 0.0033 0.0039
Brugia malayi Melatonin receptor type 1A 0.0028 0.0017 0.0041
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0069 0.0139 0.0364
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Toxoplasma gondii hexokinase 0.0088 0.0195 0.0555
Leishmania major 3-keto-dihydrosphingosine reductase 0.0046 0.0073 0.0903
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0303 0.084 0.101
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.005 0.0082 0.0049
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Onchocerca volvulus 0.0067 0.0135 0.0529
Trypanosoma brucei hexokinase 0.0088 0.0195 0.3052
Onchocerca volvulus 0.0035 0.0038 0.0095
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.005 0.0082 0.0049
Giardia lamblia Grp94/Hsp90 0.007 0.0142 0.1141
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0058 0.0107 0.0128
Echinococcus granulosus transportin 1 0.004 0.0053 0.0064
Onchocerca volvulus 0.01 0.0234 0.0972
Trichomonas vaginalis endoplasmin, putative 0.0054 0.0094 0.0264
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0038 0.0006
Brugia malayi nuclear hormone receptor 0.0042 0.0059 0.0143
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Trypanosoma cruzi short chain dehydrogenase, putative 0.0046 0.0073 0.0903
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.1015 0.2968 0.2945
Entamoeba histolytica heat shock protein 90, putative 0.0079 0.017 0.1698
Brugia malayi beta-lactamase family protein 0.0035 0.0038 0.0092
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0204 0.0543 0.0653
Brugia malayi Pax transcription activation domain interacting protein 0.006 0.0113 0.0275
Echinococcus granulosus sex peptide receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Giardia lamblia Hypothetical protein 0.0046 0.0073 0.042
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0046 0.0073 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0017 0.002
Schistosoma mansoni myosin xvIII 0.0028 0.0017 0.002
Plasmodium falciparum enoyl-acyl carrier reductase 0.1015 0.2968 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0038 0.0073
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Brugia malayi Hexokinase family protein 0.0055 0.0098 0.0238
Echinococcus multilocularis chromobox protein 1 0.007 0.0142 0.0171
Mycobacterium leprae Conserved hypothetical protein 0.005 0.0082 0.0167
Loa Loa (eye worm) oxidoreductase 0.0069 0.0139 0.0208
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0058 0.0107 0.0128
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0073 0.0903
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0073 0.0087
Loa Loa (eye worm) latrophilin receptor protein 2 0.015 0.0383 0.0573
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Giardia lamblia Heat shock protein HSP 90-alpha 0.0079 0.017 0.1439
Loa Loa (eye worm) hypothetical protein 0.006 0.0113 0.0169
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0059 0.0071
Echinococcus granulosus hexokinase 0.0088 0.0195 0.0235
Loa Loa (eye worm) hypothetical protein 0.006 0.0113 0.0169
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0033 0.0079
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0167 0.0432 0.1047
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Loa Loa (eye worm) endoplasmin 0.0079 0.017 0.0254
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.015 0.0383 0.046
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0071 0.0146 0.0218
Onchocerca volvulus 0.0058 0.0107 0.0403
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0017 0.0025
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0058 0.0107 0.0128
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0073 0.0137
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0064 0.0077
Brugia malayi hypothetical protein 0.0117 0.0284 0.069
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.007 0.0142 0.0109
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0069 0.0139 0.0107
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0038 0.0092
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0046 0.0073 0.0752
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0059 0.0071
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0204 0.0543 0.0653
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0058 0.0107 0.0128
Brugia malayi Hsp90 protein 0.0044 0.0066 0.016
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.006 0.0113 0.1122
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0172 0.0257
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Onchocerca volvulus 0.0046 0.0073 0.025
Loa Loa (eye worm) hypothetical protein 0.0776 0.2251 0.3366
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0046 0.0073 0.004
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Trypanosoma brucei glucosidase, putative 0.0044 0.0064 0.0593
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0017 0.002
Entamoeba histolytica heat shock transcription factor, putative 0.01 0.0233 0.2336
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0234 0.0281
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0038 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Brugia malayi Trypsin-like protease protein 5 0.0204 0.0543 0.1318
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0046 0.0073 0.025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0348 0.0418
Echinococcus multilocularis cpg binding protein 0.0031 0.0025 0.003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0655 0.1892 0.4589
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Echinococcus granulosus transmembrane protease serine 3 0.0204 0.0543 0.0653
Entamoeba histolytica hypothetical protein 0.0178 0.0464 0.4684
Trichomonas vaginalis set domain proteins, putative 0.0287 0.079 0.2622
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0064 0.0162
Trypanosoma cruzi heat shock protein 85, putative 0.0079 0.017 0.3095
Echinococcus granulosus chromobox protein 1 0.007 0.0142 0.0171
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0057
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0069 0.0139 0.0107
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0057
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0073 0.004
Schistosoma mansoni hypothetical protein 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0017 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0017 0.002
Schistosoma mansoni amine GPCR 0.0028 0.0017 0.002
Schistosoma mansoni hypothetical protein 0.0028 0.0017 0.002
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.006 0.0113 0.0081
Echinococcus granulosus pyruvate kinase 0.0033 0.0033 0.0039
Onchocerca volvulus 0.0042 0.0059 0.019
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Toxoplasma gondii carbonyl reductase 1, putative 0.0046 0.0073 0.0137
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0059 0.0143
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0073 0.0752
Onchocerca volvulus 0.0099 0.0231 0.0959
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Echinococcus granulosus heat shock protein 0.0079 0.017 0.0204
Onchocerca volvulus 0.0776 0.2251 1
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0069 0.0139 0.1999
Loa Loa (eye worm) TK/ROR protein kinase 0.0058 0.0107 0.016
Loa Loa (eye worm) hypothetical protein 0.0182 0.0477 0.0713
Onchocerca volvulus 0.0046 0.0073 0.025
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.005 0.0082 0.0049
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0294 0.0439
Trypanosoma brucei PAB1-binding protein , putative 0.0182 0.0477 0.8322
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0069 0.0139 0.0364
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0059 0.0088
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.008 0.0096
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0058 0.0107 0.0128
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0038 0.0057
Schistosoma mansoni coup transcription factor 0.0042 0.0059 0.0071
Loa Loa (eye worm) retinol dehydrogenase 12 0.0069 0.0139 0.0208
Echinococcus multilocularis G protein coupled receptor 139 0.0128 0.0318 0.0382
Onchocerca volvulus 0.0058 0.0107 0.0403
Brugia malayi sulfakinin receptor protein 0.0028 0.0017 0.0041
Onchocerca volvulus 0.0088 0.0195 0.08
Trypanosoma brucei importin beta-1 subunit, putative 0.0212 0.0566 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Brugia malayi RNA, U transporter 1 0.0602 0.1733 0.4204
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Onchocerca volvulus 0.0046 0.0073 0.025
Brugia malayi Endoplasmin precursor 0.0079 0.017 0.0412
Echinococcus multilocularis transportin 1 0.004 0.0053 0.0064
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Brugia malayi Dehydrogenases, short chain protein 2 0.0046 0.0073 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Echinococcus multilocularis pyruvate kinase 0.0033 0.0033 0.0039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0082 0.0177 0.0213
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0118 0.1915
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.1015 0.2968 1
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0069 0.0139 0.0167
Loa Loa (eye worm) hypothetical protein 0.0069 0.0139 0.0208
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0069 0.0139 0.0338
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Schistosoma mansoni amine GPCR 0.0028 0.0017 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.0477 1
Schistosoma mansoni chromosome transmission fidelity factor 0.006 0.0113 0.0136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Schistosoma mansoni pcd6 interacting protein-related 0.0058 0.0107 0.0128
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0058 0.0107 0.0128
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0051 0.0086 0.1206
Brugia malayi Protein-tyrosine phosphatase 1 0.0058 0.0107 0.0259
Brugia malayi chromobox protein homolog 3 0.0039 0.0051 0.0123
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0017 0.002
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0059 0.0071
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.005 0.0082 0.0049
Echinococcus multilocularis enteropeptidase 0.0204 0.0543 0.0653
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.006 0.0113 0.0328
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.008 0.0048
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.005 0.0082 0.0049
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0017 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Schistosoma mansoni biogenic amine receptor 0.0028 0.0017 0.002
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Plasmodium vivax SET domain protein, putative 0.0037 0.0043 0.0037
Loa Loa (eye worm) importin-beta domain-containing protein 0.004 0.0053 0.008
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Trichomonas vaginalis heat shock protein, putative 0.0066 0.013 0.0385
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0017 0.002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1622 0.478 0.5742
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0058 0.0107 0.016
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0073 0.071
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0146 0.1451
Schistosoma mansoni histamine h1 receptor 0.0028 0.0017 0.002
Schistosoma mansoni hypothetical protein 0.0325 0.0905 0.1087
Echinococcus granulosus g protein coupled receptor 0.0028 0.0017 0.002
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0046 0.0073 0.019
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Brugia malayi ORL1-like opioid receptor 0.0028 0.0017 0.0041
Loa Loa (eye worm) CYP4Cod1 0.0129 0.0318 0.0476
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0046 0.0073 0.0903
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.005 0.0082 0.0049
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0172 0.3137
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0057
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Schistosoma mansoni importin beta-1 0.0212 0.0566 0.068
Plasmodium vivax hexokinase, putative 0.0088 0.0195 0.0555
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0043 0.0052
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0033 0.0079
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Loa Loa (eye worm) hypothetical protein 0.0204 0.0543 0.0812
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0046 0.0073 0.0087
Schistosoma mansoni protein tyrosine phosphatase 0.0058 0.0107 0.0128
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.005 0.0082 0.0049
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Schistosoma mansoni endoplasmin 0.0079 0.017 0.0204
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0348 0.0418
Treponema pallidum hexokinase (hxk) 0.0088 0.0195 0.094
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.005 0.0082 0.0049
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0118 0.0141
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0017 0.002
Trichomonas vaginalis replication factor C large subunit, putative 0.006 0.0113 0.0328
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.006 0.0113 0.0328
Leishmania major hypothetical protein, conserved 0.0058 0.0107 0.168
Loa Loa (eye worm) kap beta 3 protein 0.004 0.0053 0.008
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.0522 0.0627
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0137
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Entamoeba histolytica hexokinase 2 0.0088 0.0195 0.1957
Trichomonas vaginalis steroid dehydrogenase, putative 0.0046 0.0073 0.019
Leishmania major cytochrome p450-like protein 0.005 0.0082 0.1106
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0543 0.0653
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0051 0.0086 0.0847
Schistosoma mansoni hypothetical protein 0.0204 0.0543 0.0653
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0046 0.0073 0.0137
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0044 0.0066 0.0079
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.0988 1
Brugia malayi hypothetical protein 0.006 0.0113 0.0275
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0006
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Giardia lamblia Short-chain dehydrogenase, putative 0.0046 0.0073 0.042
Brugia malayi follicle stimulating hormone receptor 0.0028 0.0017 0.0041
Brugia malayi Trypsin family protein 0.0204 0.0543 0.1318
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0073 0.0087
Brugia malayi hypothetical protein 0.0046 0.0073 0.0176
Echinococcus multilocularis tumor protein p63 0.0686 0.1984 0.2383
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Leishmania major tyrosine specific protein phosphatase, putative 0.0058 0.0107 0.1671
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.005 0.0082 0.0049
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0064 0.0108
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0172 0.0447 0.1458
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0017 0.002
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0017 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.0449 0.0418
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0115 0.0278 0.5528
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0017 0.002
Trypanosoma brucei pteridine reductase 1 0.0069 0.0139 0.1999
Brugia malayi hypothetical protein 0.0182 0.0477 0.1157
Echinococcus granulosus importin 5 0.004 0.0053 0.0064
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.008 0.0891
Entamoeba histolytica hypothetical protein 0.0046 0.0073 0.071
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0073 0.0087
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Toxoplasma gondii ABC1 family protein 0.0035 0.0038 0.0019
Echinococcus multilocularis transcription factor btf3 0.0042 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.0051
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0046 0.0073 0.0903
Brugia malayi latrophilin 2 splice variant baaae 0.0325 0.0905 0.2194
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0069 0.0139 0.0107
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0059 0.0071
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0167 0.0432 0.0518
Plasmodium falciparum heat shock protein 90, putative 0.0189 0.0498 0.1585
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0059 0.0143
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0059 0.019
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0058 0.0107 0.0128
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.009 0.0203 0.1781
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Echinococcus granulosus orexin receptor type 2 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0046 0.0073 0.004
Trypanosoma cruzi FHA domain containing protein, putative 0.006 0.0113 0.1817
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0046 0.0073 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0113 0.0328
Loa Loa (eye worm) hypothetical protein 0.01 0.0234 0.035
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0073 0.0903
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0058 0.0107 0.0128
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0073 0.0087
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0115 0.0278 0.0837
Loa Loa (eye worm) cytochrome P450 family protein 0.0144 0.0363 0.0543
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Loa Loa (eye worm) cytochrome P450 family protein 0.0129 0.0318 0.0476
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Toxoplasma gondii HEAT repeat-containing protein 0.0212 0.0566 0.1819
Brugia malayi dehydrogenases, short chain protein 2 0.0046 0.0073 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Echinococcus multilocularis transmembrane protease serine 3 0.0204 0.0543 0.0653
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0017 0.0025
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0092 0.0203
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0059 0.019
Onchocerca volvulus 0.0058 0.0107 0.0403
Schistosoma mansoni biogenic amine receptor 0.0028 0.0017 0.002
Onchocerca volvulus 0.0058 0.0107 0.0403
Entamoeba histolytica hypothetical protein 0.0042 0.006 0.0581
Mycobacterium ulcerans oxidoreductase 0.0069 0.0139 0.0107
Onchocerca volvulus 0.0204 0.0543 0.2356
Onchocerca volvulus 0.0088 0.0195 0.08
Schistosoma mansoni ets-related 0.0222 0.0597 0.0717
Plasmodium falciparum heat shock protein 90 0.0079 0.017 0.0468
Echinococcus granulosus pyruvate kinase 0.0033 0.0033 0.0039
Echinococcus multilocularis nibrin 0.006 0.0113 0.0136
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Echinococcus granulosus neuropeptide receptor 0.0128 0.0318 0.0382
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Onchocerca volvulus 0.0035 0.0038 0.0095
Loa Loa (eye worm) hexokinase type II 0.0088 0.0195 0.0292
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0064 0.0162
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0017 0.002
Brugia malayi Protein-tyrosine phosphatase 0.0058 0.0107 0.0259
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0051 0.0086 0.0209
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.006 0.0113 0.0275
Schistosoma mansoni endoplasmin 0.0079 0.017 0.0204
Onchocerca volvulus 0.0058 0.0107 0.0403
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0017 0.002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.033 0.0921 0.1106
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0146 0.0114
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0046 0.0073 0.0903
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0017 0.002
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0059 0.0071
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0051 0.0086 0.056
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0017 0.002
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0069 0.0139 0.0364
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0118 0.1915
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.005 0.0082 0.0049
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0058 0.0107 0.1056
Plasmodium falciparum steroid dehydrogenase, putative 0.0046 0.0073 0.0137
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0017 0.002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0146 0.0114
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0059 0.0071
Echinococcus multilocularis retinol dehydrogenase 11 0.0046 0.0073 0.0087
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0046 0.0073 0.0176
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0046 0.0073 0.0109
Brugia malayi beta-NAC-like protein 0.0042 0.006 0.0145
Schistosoma mansoni heat shock protein 0.0044 0.0066 0.0079
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0017 0.002
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.005 0.0382
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0046 0.0073 0.0137
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Onchocerca volvulus 0.0058 0.0107 0.0403
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0046 0.0073 0.004
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.005 0.0082 0.0049
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0017 0.002
Plasmodium falciparum cysteine repeat modular protein 1 0.0058 0.0107 0.0254
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.006 0.0113 0.1817
Mycobacterium ulcerans hypothetical protein 0.0204 0.0543 0.0512
Trypanosoma cruzi heat shock protein, putative 0.0044 0.0066 0.0748
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0151 0.0384 0.0575
Onchocerca volvulus 0.0204 0.0543 0.2356
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0115 0.0278 0.0246
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0294 0.0439
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Plasmodium vivax enoyl-acyl carrier protein reductase 0.1015 0.2968 1
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0017 0.002
Trypanosoma brucei heat shock protein 90, putative 0.0079 0.017 0.2575
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0059 0.0143
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0017 0.002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0017 0.002
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.005 0.0082 0.0049
Schistosoma mansoni protein tyrosine phosphatase 0.0058 0.0107 0.0128
Echinococcus multilocularis hexokinase type 2 0.0088 0.0195 0.0235
Echinococcus multilocularis neuropeptide s receptor 0.0493 0.1406 0.1688
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Echinococcus granulosus hypothetical protein 0.0046 0.0073 0.0087
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0058 0.0107 0.0128
Echinococcus multilocularis geminin 0.157 0.4626 0.5557
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0046 0.0073 0.0087
Mycobacterium ulcerans heat shock protein 90 0.007 0.0142 0.0109
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.009 0.0203 0.058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Mycobacterium ulcerans dehydrogenase 0.0046 0.0073 0.004
Schistosoma mansoni hypothetical protein 0.0178 0.0464 0.0558
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0058 0.0107 0.0128
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Loa Loa (eye worm) hypothetical protein 0.0121 0.0296 0.0443
Echinococcus granulosus GPCR family 2 0.015 0.0383 0.046
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.008 0.0096
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0064 0.0162
Leishmania major oxidoreductase-like protein 0.0115 0.0278 0.5528
Trypanosoma cruzi heat shock protein 85, putative 0.0079 0.017 0.3095
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0073 0.004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0017 0.002
Brugia malayi Serotonin receptor 0.0028 0.0017 0.0041
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0017 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0043 0.0052
Schistosoma mansoni hypothetical protein 0.0028 0.0017 0.002
Chlamydia trachomatis DNA ligase 0.006 0.0113 0.0275
Onchocerca volvulus 0.0035 0.0038 0.0095
Brugia malayi hypothetical protein 0.0204 0.0543 0.1318
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Trypanosoma brucei cytochrome P450, putative 0.0129 0.0318 0.5356
Echinococcus granulosus ubiquitin specific protease 41 0.0051 0.0086 0.0103
Brugia malayi Dopamine receptor protein 1 0.0028 0.0017 0.0041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Onchocerca volvulus Sepiapterin reductase homolog 0.0046 0.0073 0.025
Echinococcus granulosus tumor protein p63 0.0686 0.1984 0.2383
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0069 0.0139 0.0338
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.007 0.0142 0.0238
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0051 0.0086 0.0103
Onchocerca volvulus 0.0058 0.0107 0.0403
Schistosoma mansoni transcription factor btf3 0.0042 0.006 0.0072
Echinococcus multilocularis hexokinase 0.0088 0.0195 0.0235
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0543 0.0653
Loa Loa (eye worm) cytochrome P450 family protein 0.0129 0.0318 0.0476
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0017 0.0041
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.009 0.0203 0.3832
Onchocerca volvulus 0.0046 0.0073 0.025
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0058 0.0107 0.0128
Trypanosoma cruzi importin beta-1 subunit, putative 0.0172 0.0447 0.9324
Brugia malayi Dopamine receptor protein 2 0.0028 0.0017 0.0041
Brugia malayi RE15519p 0.0028 0.0017 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0064 0.0713
Onchocerca volvulus 0.0058 0.0107 0.0403
Onchocerca volvulus 0.0058 0.0107 0.0403
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Giardia lamblia Protein tyrosine phosphatase 0.0058 0.0107 0.0777
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0059 0.0143
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0069 0.0139 0.0107
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.1015 0.2968 1
Echinococcus multilocularis hypothetical protein 0.0058 0.0107 0.0128
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Trichomonas vaginalis heat shock protein, putative 0.007 0.0142 0.0424
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Onchocerca volvulus 0.0058 0.0107 0.0403
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0137
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Onchocerca volvulus 0.0058 0.0107 0.0403
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0044 0.0066 0.0219
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.005 0.0082 0.0049
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0017 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0683 0.2258
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0115 0.0278 0.0246
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0046 0.0073 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0683 0.2258
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0073 0.0752
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.005 0.0082 0.0049
Schistosoma mansoni amine GPCR 0.0028 0.0017 0.002
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.005 0.0082 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.006 0.0147
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0118 0.0141
Onchocerca volvulus 0.0088 0.0195 0.08
Echinococcus granulosus microtubule associated protein 2 0.2809 0.8325 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0139 0.0208
Onchocerca volvulus 0.0058 0.0107 0.0403
Leishmania major dehydrogenase-like protein 0.0046 0.0073 0.0903
Loa Loa (eye worm) fli-1 protein 0.0222 0.0597 0.0893
Brugia malayi Protein kinase domain containing protein 0.0058 0.0107 0.026
Echinococcus multilocularis heat shock protein 90 0.0079 0.017 0.0204
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0073 0.0903
Loa Loa (eye worm) heat shock protein 90 0.0079 0.017 0.0254
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0118 0.1915
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Echinococcus multilocularis somatostatin receptor 0.0028 0.0017 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0046 0.0073 0.0752
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Loa Loa (eye worm) hypothetical protein 0.0071 0.0146 0.0218
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0059 0.0143
Plasmodium vivax endoplasmin, putative 0.0079 0.017 0.0468
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0017 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.0051
Trypanosoma brucei importin beta-1 subunit, putative 0.0212 0.0566 1
Brugia malayi neuropeptide F receptor 0.0028 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Schistosoma mansoni opsin-like receptor 0.0028 0.0017 0.002
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0017 0.002
Schistosoma mansoni pyruvate kinase 0.0033 0.0033 0.0039
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0051 0.0086 0.1003
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Schistosoma mansoni chromobox protein 0.007 0.0142 0.0171
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0017 0.002
Entamoeba histolytica short chain dehydrogenase family protein 0.0046 0.0073 0.071
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0152 0.0228
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0058 0.0107 0.1671
Onchocerca volvulus 0.0046 0.0073 0.025
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.008 0.1071
Schistosoma mansoni carbonyl reductase 0.0046 0.0073 0.0087
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0303 0.084 0.101
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0073 0.0903
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Schistosoma mansoni amine GPCR 0.0028 0.0017 0.002
Brugia malayi isocitrate dehydrogenase 0.0049 0.008 0.0194
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0046 0.0073 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0118 0.0343
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Entamoeba histolytica short chain dehydrogenase family protein 0.0046 0.0073 0.071
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0167 0.0432 0.0645
Loa Loa (eye worm) pax transcription factor protein 2 0.0243 0.066 0.0986
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0064 0.0077
Leishmania major heat shock protein, putative 0.0044 0.0066 0.0748
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0017 0.002
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0069 0.0139 0.0107
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.015 0.0383 0.046
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0146 0.2546
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Plasmodium falciparum importin beta, putative 0.0212 0.0566 0.1819
Entamoeba histolytica Ran family GTPase 0.009 0.0203 0.2031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.002 0.0031
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.0477 0.1514
Echinococcus multilocularis glycoprotein Antigen 5 0.0204 0.0543 0.0653
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0058 0.0107 0.0254
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0059 0.0071
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0046 0.0073 0.0137
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0017 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0038 0.0073
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.007 0.0142 0.2454
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.2261 0.6688 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0073 0.004
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0094 0.0264
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0073
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0033 0.0071
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0073 0.004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.06 0.0569
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0146 0.2546
Echinococcus granulosus chromobox protein 1 0.007 0.0142 0.0171
Brugia malayi Muscleblind-like protein 0.0151 0.0384 0.0932
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0046 0.0073 0.0903
Leishmania major lanosterol 14-alpha-demethylase, putative 0.005 0.0082 0.1106
Plasmodium vivax importin-beta 2, putative 0.0212 0.0566 0.1819
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0017 0.002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0051 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0038 0.0125
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0059 0.0071
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0038 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0073 0.004
Chlamydia trachomatis oxoacy-ACP reductase 0.0069 0.0139 0.0364
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0425 0.1385
Onchocerca volvulus Huntingtin homolog 0.0121 0.0296 0.1252
Loa Loa (eye worm) hypothetical protein 0.0053 0.0092 0.0138
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0988 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Schistosoma mansoni hypothetical protein 0.015 0.0383 0.046
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0046 0.0073 0.004
Entamoeba histolytica hypothetical protein 0.006 0.0113 0.1122
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0046 0.0073 0.0087
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0051 0.0086 0.0103
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0017 0.002
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0058 0.0107 0.0128
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.008 0.0096
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.1015 0.2968 1
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0073 0.0903
Brugia malayi Pre-SET motif family protein 0.0252 0.0687 0.1665
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0038 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0051 0.0116
Onchocerca volvulus 0.0046 0.0073 0.025
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.0522 0.0627
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0073 0.0903
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0172 0.3137
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0017 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.0683 0.1021
Mycobacterium leprae Probable oxidoreductase 0.0046 0.0073 0.0137
Schistosoma mansoni cpg binding protein 0.0031 0.0025 0.003
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0058 0.0107 0.016
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0069 0.0139 0.2402
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0017 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Schistosoma mansoni neuropeptide receptor 0.0028 0.0017 0.002
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.0634 0.0761
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0059 0.0071
Mycobacterium tuberculosis Conserved protein 0.0035 0.0038 0.0006
Loa Loa (eye worm) hypothetical protein 0.0325 0.0905 0.1353
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0073 0.004
Schistosoma mansoni hypothetical protein 0.0048 0.0077 0.0092
Echinococcus multilocularis serotonin receptor 0.0028 0.0017 0.002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Onchocerca volvulus 0.0058 0.0107 0.0403
Trypanosoma cruzi cytochrome P450, putative 0.0129 0.0318 0.6436
Schistosoma mansoni heat shock protein 0.0079 0.017 0.0204
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0017 0.002
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0543 0.0653
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0167 0.0432 0.0518
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0059 0.0143
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0069 0.0139 0.0167
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0069 0.0139 0.0107
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Echinococcus granulosus hexokinase 0.0088 0.0195 0.0235
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Plasmodium falciparum basic transcription factor 3b, putative 0.0042 0.006 0.0093
Loa Loa (eye worm) hexokinase 0.0055 0.0098 0.0146
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.008 0.0891
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0178 0.0464 0.0558
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.008 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0113 0.0328
Echinococcus granulosus neuropeptide receptor A26 0.0493 0.1406 0.1688
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0064 0.0713
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0017 0.002
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0073 0.0087
Trypanosoma cruzi hexokinase, putative 0.0088 0.0195 0.3667
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Echinococcus granulosus cpg binding protein 0.0031 0.0025 0.003
Loa Loa (eye worm) ICD-1 protein 0.0042 0.006 0.009
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0058 0.0107 0.016
Onchocerca volvulus 0.0243 0.066 0.2878
Toxoplasma gondii oxidoreductase, putative 0.0046 0.0073 0.0137
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0058 0.0107 0.0128
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Echinococcus multilocularis hexokinase 0.0088 0.0195 0.0235
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.0137
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0121 0.0146
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.006 0.0113 0.0275
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0046 0.0073 0.004
Echinococcus granulosus hypothetical protein 0.0028 0.0017 0.002
Brugia malayi hypothetical protein 0.0121 0.0296 0.0719
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0046 0.0073 0.0903
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Leishmania major basic transcription factor 3a, putative 0.0042 0.006 0.0616
Trypanosoma brucei Heat shock protein 83, putative 0.0079 0.017 0.2575
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0118 0.0141
Echinococcus granulosus geminin 0.157 0.4626 0.5557
Onchocerca volvulus 0.0287 0.079 0.3462
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Brugia malayi Cytochrome P450 family protein 0.0129 0.0318 0.0773
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Brugia malayi hypothetical protein 0.0058 0.0107 0.0259
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0046 0.0073 0.0137
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0017 0.0025
Brugia malayi hypothetical protein 0.0046 0.0073 0.0176
Trypanosoma brucei protein tyrosine phosphatase 1 0.0058 0.0107 0.139
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1402 0.4122 0.4952
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0017 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0017 0.002
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0046 0.0073 0.0752
Onchocerca volvulus 0.0048 0.0077 0.0272
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0059 0.0071
Schistosoma mansoni topbp1 0.006 0.0113 0.0136
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0046 0.0073 0.0903
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0064 0.0713
Echinococcus granulosus carbonyl reductase 1 0.0046 0.0073 0.0087
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Onchocerca volvulus 0.0303 0.084 0.3687
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0059 0.0191
Echinococcus granulosus g protein coupled receptor 0.0028 0.0017 0.002
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0046 0.0073 0.0903
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Loa Loa (eye worm) cytochrome P450 0.005 0.0082 0.0122
Loa Loa (eye worm) heat shock protein 75 0.0044 0.0066 0.0098
Schistosoma mansoni survival motor neuron protein 0.0048 0.0077 0.0092
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0058 0.0107 0.016
Schistosoma mansoni chromobox protein 0.007 0.0142 0.0171
Echinococcus multilocularis endoplasmin 0.007 0.0142 0.017
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0059 0.0071
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0017 0.002
Mycobacterium ulcerans hypothetical protein 0.0035 0.0038 0.0006
Echinococcus multilocularis retinol dehydrogenase 11 0.0046 0.0073 0.0087
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Plasmodium vivax basic transcription factor 3b, putative 0.0042 0.006 0.0093
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0058 0.0107 0.0128
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0017 0.0041
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0046 0.0073 0.0903
Schistosoma mansoni retinal dehydrogenase 0.0046 0.0073 0.0087
Onchocerca volvulus 0.0055 0.0098 0.0363
Schistosoma mansoni amine GPCR 0.0028 0.0017 0.002
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0046 0.0073 0.0903
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.006 0.0616
Trypanosoma cruzi heat shock protein 85, putative 0.0066 0.013 0.2196
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Brugia malayi Hexokinase family protein 0.0027 0.0015 0.0036
Onchocerca volvulus 0.0046 0.0073 0.025
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0425 0.1385
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.0634 0.0761
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0069 0.0139 0.0167
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0017 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0043 0.0052
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Mycobacterium ulcerans hypothetical protein 0.0071 0.0146 0.0114
Loa Loa (eye worm) hypothetical protein 0.0079 0.0171 0.0255
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0017 0.002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0118 0.1915
Loa Loa (eye worm) dehydrogenase 0.0046 0.0073 0.0109
Mycobacterium tuberculosis Possible oxidoreductase 0.0069 0.0139 0.0107
Trypanosoma cruzi heat shock protein 90, putative 0.0079 0.017 0.3095
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0058 0.0107 0.0128
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0017 0.002
Plasmodium vivax heat shock protein 90, putative 0.0044 0.0066 0.0113
Brugia malayi Serotonin receptor 0.0028 0.0017 0.0041
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1402 0.4122 0.6164
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.005 0.0082 0.0049
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0033 0.0071
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0058 0.0107 0.0128
Entamoeba histolytica HEAT repeat domain containing protein 0.004 0.0053 0.0515
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.005 0.0082 0.0049
Mycobacterium ulcerans ketoacyl reductase 0.0046 0.0073 0.004
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0988 1
Loa Loa (eye worm) hypothetical protein 0.0303 0.084 0.1257
Plasmodium vivax heat shock protein 86, putative 0.0079 0.017 0.0468
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0059 0.019
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0064 0.0162
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0051 0.0086 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.005 0.0082 0.0049
Loa Loa (eye worm) hypothetical protein 0.006 0.0112 0.0168
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0118 0.1594
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0152 0.0183
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0053 0.0092 0.0138
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0086 0.0236
Trichomonas vaginalis heat shock protein, putative 0.0079 0.017 0.052
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.006 0.0113 0.0275
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.005 0.0082 0.0049
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0058 0.0107 0.0128
Schistosoma mansoni hypothetical protein 0.005 0.0082 0.0098
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0017 0.0041
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0038 0.0046
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0017 0.0041
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0046 0.0073 0.071
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0059 0.0071
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0073 0.004
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0092 0.0203
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0017 0.002
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0046 0.0073 0.019
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.1015 0.2968 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0058 0.0107 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.006 0.0147
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0059 0.0071
Mycobacterium ulcerans lipase LipD 0.0035 0.0038 0.0006
Schistosoma mansoni neuropeptide receptor 0.0028 0.0017 0.002
Onchocerca volvulus 0.0058 0.0107 0.0403
Brugia malayi larval opioid receptor 0.0028 0.0017 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Leishmania major importin beta-1 subunit, putative 0.0172 0.0447 0.9324
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0059 0.0071
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0046 0.0073 0.0176
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0059 0.0071
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0038 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0058 0.0107 0.0128
Schistosoma mansoni pyruvate kinase 0.0033 0.0033 0.0039
Brugia malayi putative neuropeptide receptor 0.0028 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0043 0.0052
Schistosoma mansoni ran 0.009 0.0203 0.0244
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0069 0.0139 0.0107
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0038 0.0019
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0118 0.1915
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0017 0.002
Echinococcus granulosus allatostatin A receptor 0.0028 0.0017 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.0477 0.1514
Trichomonas vaginalis chromobox protein, putative 0.007 0.0142 0.0426
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0046 0.0073 0.071
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0092 0.006
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0044 0.0066 0.064
Loa Loa (eye worm) dehydrogenase 0.0046 0.0073 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Brugia malayi MH2 domain containing protein 0.0121 0.0294 0.0713
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0064 0.0162
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0073 0.0903
Loa Loa (eye worm) hypothetical protein 0.0039 0.0051 0.0076
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0059 0.0143
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Echinococcus multilocularis muscleblind protein 0.0151 0.0384 0.0462
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.005 0.0082 0.0049
Schistosoma mansoni alpha-glucosidase 0.0169 0.044 0.0528
Loa Loa (eye worm) hypothetical protein 0.006 0.0113 0.0169
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0146 0.2546
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0069 0.0139 0.023
Trichomonas vaginalis chromobox protein, putative 0.007 0.0142 0.0426
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0073 0.071
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0059 0.0071
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0118 0.089
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0038 0.0006
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0046 0.0073 0.0137
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Brugia malayi hypothetical protein 0.0058 0.0107 0.0259
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0017 0.002
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Brugia malayi heat shock protein 90 0.0079 0.017 0.0412
Echinococcus multilocularis neuropeptide receptor 0.0128 0.0318 0.0382
Brugia malayi DKFZp564C0469 protein 0.006 0.0113 0.0275
Onchocerca volvulus 4.1 G protein, putative homolog 0.0058 0.0107 0.0403
Leishmania major cytochrome p450-like protein 0.005 0.0082 0.1106
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Echinococcus granulosus Mastin 0.0204 0.0543 0.0653
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0069 0.0139 0.0107
Brugia malayi Trypsin family protein 0.0204 0.0543 0.1318
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0167 0.0432 0.0518
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.005 0.0082 0.0049
Loa Loa (eye worm) trypsin family protein 0.0204 0.0543 0.0812
Leishmania major hypothetical protein, conserved 0.0035 0.0038 0.0125
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.005 0.0082 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Echinococcus granulosus hexokinase 0.0088 0.0195 0.0235
Brugia malayi hypothetical protein 0.0776 0.2251 0.546
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0033 0.0054
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0073 0.071
Brugia malayi hypothetical protein 0.0058 0.0107 0.0259
Onchocerca volvulus 0.0046 0.0073 0.025
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0033 0.0054
Brugia malayi hexokinase type II 0.0028 0.0017 0.0041
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0046 0.0073 0.004
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0077 0.0186
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.008 0.0096
Plasmodium falciparum endoplasmin, putative 0.0054 0.0094 0.021
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0046 0.0073 0.0087
Onchocerca volvulus 0.0204 0.0543 0.2356
Mycobacterium ulcerans short-chain dehydrogenase 0.0046 0.0073 0.004
Echinococcus granulosus oxidoreductase 0.0046 0.0073 0.0087
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.009 0.0203 0.058
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0064 0.0625
Onchocerca volvulus 0.0058 0.0107 0.0403
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0017 0.002
Loa Loa (eye worm) hexokinase 0.0088 0.0195 0.0292
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0064 0.0096
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Brugia malayi Fli-1 protein 0.0222 0.0597 0.1449
Brugia malayi Dopamine receptor 0.0028 0.0017 0.0041
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0017 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0543 0.0653
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0059 0.0143
Plasmodium falciparum hexokinase 0.0088 0.0195 0.0555
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0046 0.0073 0.0087
Trypanosoma brucei heat shock protein 90, putative 0.0079 0.017 0.2575
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0683 0.2258
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0172 0.3137
Echinococcus granulosus neuropeptide s receptor 0.0493 0.1406 0.1688
Echinococcus granulosus retinol dehydrogenase 11 0.0046 0.0073 0.0087
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Trichomonas vaginalis esterase, putative 0.0035 0.0038 0.0073
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0046 0.0073 0.0752
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0073 0.0087
Leishmania major hypothetical protein, conserved 0.0046 0.0073 0.0903
Entamoeba histolytica hypothetical protein 0.0178 0.0464 0.4684
Leishmania major hypothetical protein, conserved 0.0182 0.0477 1
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0017 0.002
Entamoeba histolytica hypothetical protein 0.0172 0.0447 0.4507
Trypanosoma brucei protein kinase, putative 0.0062 0.0118 0.1594
Schistosoma mansoni heat shock protein 0.0079 0.017 0.0204
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0059 0.0088
Echinococcus multilocularis microtubule associated protein 2 0.2809 0.8325 1
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0038 0.0006
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0046 0.0073 0.019
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Plasmodium falciparum transportin 0.004 0.0053 0.0071
Mycobacterium tuberculosis Probable dehydrogenase 0.0046 0.0073 0.004
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0046 0.0073 0.0903
Brugia malayi hypothetical protein 0.0028 0.0017 0.0041
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0137
Mycobacterium ulcerans carveol-like dehydrogenase 0.0046 0.0073 0.004
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.008 0.1071
Onchocerca volvulus 0.0046 0.0073 0.025
Giardia lamblia Heat shock protein HSP 90-alpha 0.0066 0.013 0.1021
Toxoplasma gondii oxidoreductase, putative 0.0046 0.0073 0.0137
Echinococcus granulosus tissue type plasminogen activator 0.0058 0.0107 0.0129
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0046 0.0073 0.0903
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus multilocularis chromobox protein 1 0.007 0.0142 0.0171
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0038 0.0125
Mycobacterium ulcerans beta-lactamase 0.0035 0.0038 0.0006
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0058 0.0107 0.0128
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0058 0.0107 0.0128
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0017 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Echinococcus granulosus somatostatin receptor 0.0028 0.0017 0.002
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0204 0.0543 0.0653
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0178 0.0464 0.0558
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0146 0.0114
Echinococcus multilocularis oxidoreductase 0.0046 0.0073 0.0087
Toxoplasma gondii cytochrome p450 superfamily protein 0.005 0.0082 0.0167
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0058 0.0107 0.0128
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0146 0.0385
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0046 0.0073 0.004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0059 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0475 0.1354 0.3284
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0129 0.0318 0.0287
Loa Loa (eye worm) hypothetical protein 0.0204 0.0543 0.0812
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0017 0.002
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0046 0.0073 0.004
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0073 0.004
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0073 0.0903
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.005 0.0082 0.0049
Brugia malayi topoisomerase 0.006 0.0113 0.0275
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0069 0.0139 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0017 0.002
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0118 0.029
Onchocerca volvulus 0.0048 0.0077 0.0268
Echinococcus granulosus transcription factor btf3 0.0042 0.006 0.0072
Entamoeba histolytica heat shock protein 90, putative 0.0079 0.017 0.1698
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0073 0.0752
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0059 0.0071
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0043 0.0052
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0452 0.1475
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0058 0.0107 0.0128
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0058 0.0107 0.1671
Echinococcus multilocularis ubiquitin specific protease 41 0.0051 0.0086 0.0103
Leishmania major cytochrome p450-like protein 0.0129 0.0318 0.6436
Toxoplasma gondii heat shock protein 90, putative 0.0079 0.017 0.0468
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0017 0.002
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.008 0.0162
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0172 0.0207
Loa Loa (eye worm) hypothetical protein 0.006 0.0113 0.0169
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0038 0.0046
Brugia malayi Dehydrogenases, short chain protein 30 0.0046 0.0073 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hexokinase 0.0027 0.0015 0.0022
Leishmania major short chain dehydrogenase, putative 0.0046 0.0073 0.0903
Onchocerca volvulus 0.0115 0.0278 0.117
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0066 0.013 0.0156
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.0477 1
Toxoplasma gondii HEAT repeat-containing protein 0.004 0.0053 0.0071
Brugia malayi Isocitrate dehydrogenase 0.0049 0.008 0.0194
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0059 0.0146
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0038 0.0006
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0069 0.0139 0.0107
Brugia malayi Pre-SET motif family protein 0.0037 0.0043 0.0105
Echinococcus multilocularis heat shock protein 0.0079 0.017 0.0204
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0073 0.004
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.005 0.0082 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0038 0.0046
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.009 0.0203 0.0492
Brugia malayi Protein-tyrosine phosphatase 0.0058 0.0107 0.0259
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0348 0.0418
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.005 0.0082 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0059 0.0143
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0046 0.0073 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Loa Loa (eye worm) oxidoreductase 0.0046 0.0073 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.007 0.0142 0.0372
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0204 0.0543 0.0653
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0064 0.0162
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0017 0.002
Brugia malayi Cytochrome P450 family protein 0.005 0.0082 0.0198
Giardia lamblia Reductase, putative 0.0046 0.0073 0.042
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0017 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0102 0.0236
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.006 0.0113 0.0328
Trypanosoma brucei heat shock protein 84, putative 0.0044 0.0066 0.0623
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0064 0.0162
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0115 0.0278 0.0246
Brugia malayi steroid hormone receptor 0.0042 0.0059 0.0143
Loa Loa (eye worm) hypothetical protein 0.0058 0.0107 0.016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0059 0.0088
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Onchocerca volvulus 0.0058 0.0107 0.0403
Onchocerca volvulus 0.0058 0.0107 0.0403
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0059 0.0143
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0059 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0348 0.0418
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0073 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0146 0.0353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0059 0.0088
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0058 0.0107 0.1671
Toxoplasma gondii HEAT repeat-containing protein 0.004 0.0053 0.0071
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.0348 0.0844
Brugia malayi Latrophilin receptor protein 2 0.015 0.0383 0.0929
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0118 0.0141
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.008 0.0096
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0058 0.0107 0.1056
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0072 0.0086
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0058 0.0107 0.0128
Onchocerca volvulus 0.0204 0.0543 0.2356
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0118 0.0141
Brugia malayi GnHR receptor homolog 0.0028 0.0017 0.0041
Trichomonas vaginalis hypothetical protein 0.1015 0.2968 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0167 0.0432 0.0518
Onchocerca volvulus 0.0071 0.0146 0.0577
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0017 0.002
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0017 0.002
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.005 0.0082 0.0049
Loa Loa (eye worm) hypothetical protein 0.0051 0.0086 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0059 0.0088
Onchocerca volvulus Hexokinase homolog 0.0055 0.0098 0.0363
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.005 0.0082 0.0049
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0057
Brugia malayi AKH receptor 0.0028 0.0017 0.0041
Plasmodium vivax steroid dehydrogenase, putative 0.0046 0.0073 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0051 0.0116
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0073 0.004
Entamoeba histolytica transcription factor BTF3, putative 0.0042 0.006 0.0581
Onchocerca volvulus 0.0029 0.002 0.0016
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0172 0.1718
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0046 0.0073 0.071
Loa Loa (eye worm) hypothetical protein 0.0053 0.0092 0.0138
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0064 0.0162
Loa Loa (eye worm) hypothetical protein 0.006 0.0113 0.0169
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0041 0.0055 0.0423
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0058 0.0107 0.016
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0059 0.0071
Leishmania major pteridine reductase 1 0.0115 0.0278 0.5528
Echinococcus granulosus cytochrome P450 2K1 0.005 0.0082 0.0098
Trypanosoma brucei heat shock protein, putative 0.0079 0.017 0.2575
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.015 0.0383 0.0929
Trichomonas vaginalis hypothetical protein 0.004 0.0053 0.0125
Trypanosoma brucei hexokinase 0.0088 0.0195 0.3052
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.0113 0.1817
Loa Loa (eye worm) beta-lactamase 0.0035 0.0038 0.0057
Schistosoma mansoni hypothetical protein 0.2261 0.6688 0.8034
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0058 0.0107 0.0259
Schistosoma mansoni hypothetical protein 0.0413 0.1168 0.1403
Brugia malayi hypothetical protein 0.0058 0.0107 0.0259
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0988 0.3293
Loa Loa (eye worm) hypothetical protein 0.0046 0.0073 0.0109
Leishmania major heat shock protein 83-1 0.0079 0.017 0.3095
Onchocerca volvulus 0.0046 0.0073 0.025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0017 0.002
Entamoeba histolytica heat shock transcription factor, putative 0.01 0.0233 0.2336
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0107 0.168
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0046 0.0073 0.0137
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Schistosoma mansoni hypothetical protein 0.0062 0.012 0.0145
Trichomonas vaginalis pten, drome, putative 0.0058 0.0107 0.0306
Schistosoma mansoni DNA ligase IV 0.006 0.0113 0.0136
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.005 0.0082 0.1106
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0059 0.0071
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.0988 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.005 0.0082 0.0049
Onchocerca volvulus 0.0114 0.0274 0.115
Brugia malayi Retinol dehydrogenase 12 0.0046 0.0073 0.0176
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0033 0.0049
Onchocerca volvulus 0.0046 0.0073 0.025
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.005 0.0082 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.008 0.0096
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.1168 0.1403
Loa Loa (eye worm) hypothetical protein 0.015 0.0383 0.0573
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0051 0.0086 0.0103
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.0683 0.1657
Leishmania major quinonoid dihydropteridine reductase 0.0046 0.0073 0.0903
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0059 0.0071
Brugia malayi hexokinase 0.0088 0.0195 0.0474
Echinococcus granulosus hypothetical protein 0.0046 0.0073 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0452 0.1475
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0146 0.1451
Echinococcus granulosus hexokinase type 2 0.0088 0.0195 0.0235
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0017 0.002
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0069 0.0139 0.2402
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0059 0.0071
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0017 0.002
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.0522 0.1265
Mycobacterium ulcerans oxidoreductase 0.0046 0.0073 0.004
Echinococcus granulosus fmrfamide receptor 0.0028 0.0017 0.002
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0058 0.0107 0.0128
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0059 0.0146
Brugia malayi MAP kinase sur-1 0.0062 0.0118 0.0285
Echinococcus multilocularis snurportin 1 0.2261 0.6688 0.8034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.0051
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Echinococcus multilocularis 0.005 0.0082 0.0098
Brugia malayi nuclear receptor NHR-88 0.0042 0.0059 0.0143
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0146 0.0114
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Leishmania major hypothetical protein, conserved 0.0046 0.0073 0.0903
Echinococcus granulosus importin subunit beta 1 0.0212 0.0566 0.068
Schistosoma mansoni short chain dehydrogenase 0.0046 0.0073 0.0087
Loa Loa (eye worm) hypothetical protein 0.0204 0.0543 0.0812
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.004 0.0053 0.0392
Trypanosoma brucei short-chain dehydrogenase, putative 0.0046 0.0073 0.0752
Leishmania major short chain dehydrogenase/reductase, putative 0.0046 0.0073 0.0903
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0046 0.0073 0.004
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Echinococcus granulosus steroid dehydrogenase 0.0046 0.0073 0.0087
Mycobacterium ulcerans short chain dehydrogenase 0.0069 0.0139 0.0107
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0137
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0017 0.002
Giardia lamblia Replication factor C, subunit 1 0.006 0.0113 0.0845
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0086 0.0236
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.008 0.0162
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.005 0.0082 0.1106
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.0073 0.004
Echinococcus multilocularis carbonyl reductase 1 0.0046 0.0073 0.0087
Schistosoma mansoni hypothetical protein 0.015 0.0383 0.046
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.033 0.0921 0.1106
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0017 0.002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0046 0.0073 0.019
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0059 0.0143
Leishmania major short chain dehydrogenase-like protein 0.0046 0.0073 0.0903
Trypanosoma cruzi heat shock protein 85, putative 0.0079 0.017 0.3095
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0069 0.0139 0.2402
Leishmania major hexokinase, putative 0.0088 0.0195 0.3667
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.005 0.0082 0.0049
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0348 0.0418
Trichomonas vaginalis heat shock protein, putative 0.004 0.0054 0.0128
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.005 0.0082 0.0049
Leishmania major hypothetical protein, conserved 0.0046 0.0073 0.0903
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0046 0.0073 0.042
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0033 0.0049
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.0449 0.1419
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0425 0.1385
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0139 0.0107
Leishmania major short chain dehydrogenase/reductase, putative 0.0046 0.0073 0.0903
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0146 0.0114
Schistosoma mansoni cytochrome P450 0.005 0.0082 0.0098
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0092 0.0138
Echinococcus multilocularis steroid dehydrogenase 0.0046 0.0073 0.0087
Schistosoma mansoni hypothetical protein 0.0082 0.0177 0.0213
Echinococcus granulosus g protein coupled receptor 0.0028 0.0017 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0348 0.0418
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0172 0.0417
Schistosoma mansoni opsin-like receptor 0.0028 0.0017 0.002
Echinococcus multilocularis 0.0058 0.0107 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0113 0.0328
Echinococcus multilocularis GTP binding nuclear protein Ran 0.009 0.0203 0.0244
Echinococcus multilocularis sex peptide receptor 0.0028 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0025
Schistosoma mansoni cpg binding protein 0.0029 0.002 0.0025
Schistosoma mansoni adenoreceptor 0.0028 0.0017 0.002
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.006 0.0616
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0046 0.0073 0.025
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0058 0.0107 0.0128
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0069 0.0139 0.2402
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0088
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.0073 0.0176
Brugia malayi dehydrogenases, short chain protein 9 0.0046 0.0073 0.0176
Echinococcus granulosus enteropeptidase 0.0204 0.0543 0.0653
Schistosoma mansoni steroid dehydrogenase 0.0046 0.0073 0.0087
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0146 0.1451
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0059 0.0071
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0204 0.0543 0.1318
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0069 0.0139 0.0364
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0046 0.0073 0.0087
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0058 0.0107 0.1671
Schistosoma mansoni topbp1 0.006 0.0113 0.0136

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.92 uM DNDI: Malaria in Vitro, 72 hour ChEMBL. No reference
IC50 (functional) = 15.01 uM DNDI: Leish (axenic) in Vitro, 72 hour ChEMBL. No reference
IC50 (functional) = 17.14 uM DNDI: HAT in Vitro, 72 hour ChEMBL. No reference
IC50 (functional) > 38.17 uM DNDI: Leish (macro) in Vitro, 96 hour ChEMBL. No reference
IC50 (functional) = 40.21 uM DNDI: Chagas in Vitro, 96 hour ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Leishmania donovani ChEMBL23
Trypanosoma brucei gambiense

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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