Detailed information for compound 927288

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 288.471 | Formula: C19H32N2
  • H donors: 0 H acceptors: 0 LogP: 3.39 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CN1CCCC2=C[C@H]3C[C@@H]([C@H]12)CN1CCCC[C@H]31)C
  • InChi: 1S/C19H32N2/c1-14(2)12-21-9-5-6-15-10-16-11-17(19(15)21)13-20-8-4-3-7-18(16)20/h10,14,16-19H,3-9,11-13H2,1-2H3/t16-,17+,18+,19+/m0/s1
  • InChiKey: AJOIBIIICFESCC-WJFTUGDTSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0094 0.0094
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0007 0.0094
Loa Loa (eye worm) hypothetical protein 0.039 0.0815 0.0815
Loa Loa (eye worm) amidase 0.0121 0.0231 0.0231
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.078 0.1663 0.1663
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Brugia malayi hypothetical protein 0.002 0.0011 0.0011
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0121 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Onchocerca volvulus 0.002 0.0011 0.0002
Echinococcus granulosus insulin receptor 0.0314 0.065 0.065
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0032 0.0726
Schistosoma mansoni lipoxygenase 0.0082 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0021 0.0109
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0028 0.1176
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.02 0.0402 0.0402
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.0172 0.0172
Brugia malayi jmjC domain containing protein 0.0031 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0028 0.0101
Toxoplasma gondii HEAT repeat-containing protein 0.0085 0.0152 0.699
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0032 0.0174
Toxoplasma gondii patched family protein 0.0024 0.002 0.0777
Echinococcus granulosus replication factor c subunit 1 0.002 0.0011 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0103 0.0103
Schistosoma mansoni jumonji/arid domain-containing protein 0.0118 0.0225 0.0225
Loa Loa (eye worm) TK/ROR protein kinase 0.0067 0.0114 0.0114
Brugia malayi kap beta 3 protein 0.0016 0.0003 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.0543 0.3251
Schistosoma mansoni ran 0.0042 0.0059 0.0059
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0239 0.0487 0.2786
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0118 0.0225 0.0225
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.044 0.0924 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0172 0.4244
Brugia malayi Patched family protein 0.0024 0.002 0.002
Brugia malayi Thioredoxin reductase 0.0085 0.0152 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Brugia malayi Doublecortin family protein 0.002 0.0011 0.0011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.007 0.0121 0.0601
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0172 0.0172
Echinococcus granulosus phd:f box containing protein 0.0031 0.0035 0.0035
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0032 0.0726
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0028 0.0101
Onchocerca volvulus 0.0094 0.0172 0.0977
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0034
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0032 0.0174
Schistosoma mansoni ferritin 0.0025 0.0023 0.0023
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0085 0.0152 0.0789
Onchocerca volvulus 0.0024 0.002 0.0053
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0028 0.0101
Brugia malayi Patched family protein 0.0024 0.002 0.002
Loa Loa (eye worm) patched family protein 0.0024 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0067 0.0113 0.0113
Brugia malayi Carboxylesterase family protein 0.078 0.1663 0.1663
Onchocerca volvulus 0.003 0.0034 0.0143
Brugia malayi Importin beta-1 subunit 0.0085 0.0152 0.0152
Mycobacterium ulcerans amidase 0.0121 0.0231 0.1303
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0049
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0062 0.0102 0.4342
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0028 0.063
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0237 0.0237
Echinococcus multilocularis neuroligin 0.078 0.1663 0.1663
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0402 0.2402
Echinococcus granulosus acetylcholinesterase 0.4617 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0035 0.0035
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0726
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0049 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.0543 0.3251
Brugia malayi hypothetical protein 0.002 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0172 0.0955
Echinococcus multilocularis BC026374 protein (S09 family) 0.078 0.1663 0.1663
Brugia malayi Patched family protein 0.0024 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0193 0.0388 0.2193
Onchocerca volvulus 0.0037 0.0049 0.0234
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0172 0.0955
Leishmania major importin beta-1 subunit, putative 0.0069 0.0117 0.2868
Schistosoma mansoni loxhd1 0.002 0.0011 0.0011
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0028 0.1176
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0904 0.1932 0.1932
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0049
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0028 0.005
Schistosoma mansoni hypothetical protein 0.0161 0.0319 0.0319
Schistosoma mansoni hypothetical protein 0.0161 0.0319 0.0319
Schistosoma mansoni importin-beta 2 0.0016 0.0003 0.0003
Toxoplasma gondii hypothetical protein 0.0024 0.002 0.0777
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0031 0.0035 0.1487
Echinococcus granulosus chromobox protein 1 0.0069 0.0119 0.0119
Schistosoma mansoni polycystin 1-related 0.002 0.0011 0.0011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0059 0.0292
Echinococcus granulosus epidermal growth factor receptor 0.0982 0.2102 0.2102
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0269 0.0269
Echinococcus multilocularis chromobox protein 1 0.0069 0.0119 0.0119
Brugia malayi Carboxylesterase family protein 0.078 0.1663 0.1663
Schistosoma mansoni ferritin 0.0025 0.0023 0.0023
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0007 0.0007
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0032 0.0637
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0035 0.0035
Mycobacterium ulcerans amidase 0.0121 0.0231 0.1303
Echinococcus granulosus serine:threonine protein kinase PLK1 0.02 0.0402 0.0402
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0028 0.0028
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0007 0.0094
Echinococcus multilocularis ferritin 0.0025 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0059 0.0337
Trichomonas vaginalis ran, putative 0.0042 0.0059 0.0336
Echinococcus multilocularis transportin 1 0.0016 0.0003 0.0003
Loa Loa (eye worm) carboxylesterase 0.078 0.1663 0.1663
Echinococcus granulosus JmjC domain containing protein 4 0.0031 0.0035 0.0035
Mycobacterium ulcerans beta-lactamase 0.0037 0.0049 0.0227
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0035 0.0035
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0049
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0215 0.0435 0.2472
Onchocerca volvulus 0.0028 0.0028 0.0105
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.044 0.0924 1
Entamoeba histolytica hypothetical protein 0.0071 0.0122 0.1291
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0024 0.0021 0.0443
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0103 0.0103
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0032 0.0637
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0007 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0028 0.0028
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0113 0.0113
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0059 0.2628
Schistosoma mansoni kinase 0.0105 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0035
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0049 0.0227
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0152 0.3741
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0119 0.0697
Brugia malayi jmjC domain containing protein 0.0031 0.0035 0.0035
Echinococcus granulosus carboxylesterase 5A 0.4617 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Schistosoma mansoni hypothetical protein 0.0506 0.1069 0.1069
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0122 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0402 0.2402
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.02 0.0402 1
Entamoeba histolytica hypothetical protein 0.002 0.0011 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0402 0.2402
Entamoeba histolytica Ran family GTPase 0.0042 0.0059 0.0606
Echinococcus multilocularis sterol regulatory element binding protein 0.0167 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0085 0.0152 0.0152
Loa Loa (eye worm) patched family protein 0.0024 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0218 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Trypanosoma cruzi amidase, putative 0.0121 0.0231 0.5675
Onchocerca volvulus 0.078 0.1663 1
Treponema pallidum fructose-bisphosphate aldolase 0.044 0.0924 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0112 0.0551
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0049
Mycobacterium tuberculosis Carboxylesterase LipT 0.078 0.1663 0.9795
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0121 0.0231 0.0231
Brugia malayi Carboxylesterase family protein 0.078 0.1663 0.1663
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0028 0.0101
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0011 0.0379
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0172 0.0172
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0172 0.0172
Brugia malayi topoisomerase 0.002 0.0011 0.0011
Brugia malayi RNA, U transporter 1 0.0241 0.0491 0.0491
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0081 0.0081
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3211 0.6946 0.6946
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0028 0.0273
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0032 0.0124
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0028 0.1102
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0172 0.4244
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0052 0.0488
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0007 0.0007
Echinococcus multilocularis thioredoxin glutathione reductase 0.0085 0.0153 0.0153
Plasmodium falciparum glutathione reductase 0.0029 0.0032 0.127
Onchocerca volvulus 0.0024 0.002 0.0053
Schistosoma mansoni ferritin 0.0025 0.0023 0.0023
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0049 0.0049
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0796 0.1698 1
Entamoeba histolytica hypothetical protein 0.0071 0.0122 0.1291
Loa Loa (eye worm) oxidoreductase 0.0028 0.0028 0.0028
Schistosoma mansoni fatty-acid amide hydrolase 0.0121 0.0231 0.0231
Brugia malayi beta-lactamase 0.0037 0.0049 0.0049
Echinococcus granulosus fatty acid amide hydrolase 1 0.1002 0.2146 0.2146
Echinococcus granulosus tar DNA binding protein 0.0062 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.007 0.0121 0.0121
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0049
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0121 0.0231 0.1258
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.007 0.0121 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0402 0.2402
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.018 0.018
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Echinococcus granulosus nibrin 0.002 0.0011 0.0011
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0097 0.0097
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0121 0.0231 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.02 0.0402 0.2366
Trichomonas vaginalis esterase, putative 0.0037 0.0049 0.028
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0032 0.1356
Echinococcus multilocularis protein patched 0.0167 0.0332 0.0332
Schistosoma mansoni apoferritin-2 0.0025 0.0023 0.0023
Echinococcus multilocularis importin subunit beta 1 0.0085 0.0152 0.0152
Schistosoma mansoni lipoxygenase 0.0117 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0049 0.0227
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0103 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0032 0.0726
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0049
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.078 0.1663 0.1663
Mycobacterium ulcerans peptide amidase, GatA 0.0121 0.0231 0.1303
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0011 0.0011
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0011 0.0343
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0011 0.0011
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0052 0.2128
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.0543 0.3251
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0049 0.0049
Brugia malayi amidase 0.1002 0.2146 0.2146
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0021 0.0109
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0028 0.063
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0191 0.1133
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0021 0.0109
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0637
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0103 0.0103
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0097 0.0097
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0049 0.028
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0101 0.4591
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0637
Brugia malayi chromobox protein homolog 3 0.0039 0.0053 0.0053
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.0277 0.0277
Schistosoma mansoni amidase 0.1002 0.2146 0.2146
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0025 0.0023 0.0071
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0049 0.0049
Schistosoma mansoni phd/f-box containing protein 0.0031 0.0035 0.0035
Brugia malayi Patched family protein 0.0024 0.002 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.0543 0.3251
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0637
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0015 0.0015
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0172 0.1838
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0007 0.0007
Trypanosoma cruzi amidase, putative 0.0121 0.0231 0.5675
Brugia malayi Patched family protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Leishmania major trypanothione reductase 0.0085 0.0152 0.374
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0366 0.2183
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0035
Brugia malayi Patched family protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0059 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0191 0.1133
Loa Loa (eye worm) hypothetical protein 0.078 0.1663 0.1663
Plasmodium falciparum glutathione reductase 0.0085 0.0152 0.6544
Echinococcus granulosus expressed protein 0.0025 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Brugia malayi hypothetical protein 0.0024 0.002 0.002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0035 0.0035
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0035 0.0035
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Echinococcus granulosus Protein patched homolog 1 0.0167 0.0332 0.0332
Loa Loa (eye worm) thioredoxin reductase 0.0085 0.0152 0.0152
Onchocerca volvulus 0.0035 0.0044 0.0203
Onchocerca volvulus 0.0024 0.002 0.0053
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0193 0.0388 0.2193
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0345 0.2061
Trichomonas vaginalis conserved hypothetical protein 0.0167 0.0332 0.198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0103 0.0103
Onchocerca volvulus 0.078 0.1663 1
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0345 0.2061
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0021 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.0543 0.3251
Echinococcus granulosus importin 5 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0049 0.0177
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0021 0.0109
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.007 0.0121 0.0121
Echinococcus multilocularis Niemann Pick C1 protein 0.0557 0.1179 0.1179
Schistosoma mansoni chromobox protein 0.0069 0.0119 0.0119
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0172 0.0955
Schistosoma mansoni hypothetical protein 0.0904 0.1932 0.1932
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0314 0.065 0.065
Echinococcus multilocularis dnaJ subfamily B 0.0816 0.1741 0.1741
Echinococcus granulosus lysine specific demethylase 5A 0.0118 0.0225 0.0225
Brugia malayi Pre-SET motif family protein 0.0419 0.0878 0.0878
Toxoplasma gondii patched family protein 0.0024 0.002 0.0777
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0982 0.2102 0.2102
Schistosoma mansoni importin beta-1 0.0085 0.0152 0.0152
Trypanosoma cruzi importin beta-1 subunit, putative 0.0069 0.0117 0.2801
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0637
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0028 0.0101
Brugia malayi Protein kinase domain containing protein 0.0314 0.065 0.065
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0264 0.0543 0.0543
Brugia malayi AMP-binding enzyme family protein 0.0094 0.0172 0.0172
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0028 0.0028
Echinococcus granulosus transportin 1 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Leishmania major 4-coumarate:coa ligase-like protein 0.0094 0.0172 0.4244
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0059 0.14
Echinococcus granulosus Niemann Pick C1 protein 0.039 0.0815 0.0815
Echinococcus multilocularis geminin 0.0506 0.1069 0.1069
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0122 0.0122
Loa Loa (eye worm) patched family protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0172 0.0172
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0402 0.2402
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.0277 0.0277
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0028 0.063
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0032 0.0726
Echinococcus multilocularis epidermal growth factor receptor 0.0982 0.2102 0.2102
Onchocerca volvulus 0.0024 0.002 0.0053
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.0059
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0007 0.0007
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0007 0.0094
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0121 0.0231 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0101 0.0101
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0021 0.0456
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0215 0.0435 0.2511
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0011 0.0355
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0121 0.0231 0.0231
Leishmania major hypothetical protein, conserved 0.0121 0.0231 0.5715
Onchocerca volvulus 0.0024 0.002 0.0053
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0032 0.0032
Plasmodium vivax glutathione reductase, putative 0.0085 0.0152 0.6544
Loa Loa (eye worm) hypothetical protein 0.0061 0.0101 0.0101
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0007 0.0094
Toxoplasma gondii thioredoxin reductase 0.0085 0.0152 0.6988
Schistosoma mansoni hypothetical protein 0.0816 0.1741 0.1741
Loa Loa (eye worm) hypothetical protein 0.0205 0.0414 0.0414
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0218 0.0218
Echinococcus granulosus neuroligin 0.078 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0062 0.0102 0.0102
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0103 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Loa Loa (eye worm) histone methyltransferase 0.002 0.0012 0.0012
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.0568
Leishmania major hypothetical protein, conserved 0.0037 0.0049 0.1165
Onchocerca volvulus 0.0057 0.0093 0.0496
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0007 0.0094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Treponema pallidum bacterioferrin (TpF1) 0.0025 0.0023 0.0131
Toxoplasma gondii ABC1 family protein 0.0037 0.0049 0.2176
Loa Loa (eye worm) hypothetical protein 0.007 0.0121 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0402 0.2402
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0049 0.028
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0007 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0028 0.0028
Brugia malayi hypothetical protein 0.0024 0.002 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0345 0.2061
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0345 0.2061
Brugia malayi Patched family protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Mycobacterium tuberculosis Conserved protein 0.0037 0.0049 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0028 0.015
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0025 0.0023 0.0019
Toxoplasma gondii kringle domain-containing protein 0.0062 0.0102 0.4637
Mycobacterium tuberculosis Probable dehydrogenase 0.0193 0.0388 0.2193
Mycobacterium ulcerans lipase LipD 0.0037 0.0049 0.0227
Loa Loa (eye worm) hypothetical protein 0.0097 0.018 0.018
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0011 0.0355
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0021 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0094 0.0172 0.1838
Schistosoma mansoni BC026374 protein (S09 family) 0.078 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0049 0.0177
Echinococcus granulosus snurportin 1 0.0904 0.1932 0.1932
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0021 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0101 0.0101
Plasmodium falciparum JmjC domain-containing protein, putative 0.0031 0.0035 0.1393
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0007 0.0007
Schistosoma mansoni ferritin 0.0025 0.0023 0.0023
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0028 0.005
Echinococcus multilocularis GPCR, family 2 0.0031 0.0035 0.0035
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0028 0.0101
Echinococcus granulosus acetylcholinesterase 0.4617 1 1
Onchocerca volvulus 0.0062 0.0102 0.0552
Leishmania major hypothetical protein, conserved 0.0031 0.0035 0.0796
Brugia malayi Patched family protein 0.0024 0.002 0.002
Onchocerca volvulus 0.0028 0.0028 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0101 0.0101
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0049 0.0177
Brugia malayi hypothetical protein 0.0024 0.002 0.002
Schistosoma mansoni jumonji domain containing protein 0.0115 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0008 0.003
Toxoplasma gondii patched family protein 0.0024 0.002 0.0777
Loa Loa (eye worm) hypothetical protein 0.4617 1 1
Mycobacterium ulcerans carboxylesterase, LipT 0.078 0.1663 0.9796
Schistosoma mansoni cpg binding protein 0.0057 0.0093 0.0093
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0119 0.0697
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0094 0.0172 0.0955
Echinococcus granulosus ferritin 0.0025 0.0023 0.0023
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0193 0.0388 0.2193
Echinococcus granulosus GPCR family 2 0.0031 0.0035 0.0035
Schistosoma mansoni protein phosphatase 2C 0.0031 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0007 0.0176
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0117 0.0689
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0032 0.0726
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0021 0.0021
Echinococcus multilocularis para nitrobenzyl esterase 0.078 0.1663 0.1663
Treponema pallidum NADH oxidase 0.0029 0.0032 0.0228
Brugia malayi Protein kinase domain containing protein 0.0067 0.0114 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0021 0.0109
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0021 0.0851
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0167 0.0332 0.0332
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0028 0.0028
Giardia lamblia Replication factor C, subunit 1 0.002 0.0011 0.0047
Schistosoma mansoni ferritin light chain 0.0025 0.0023 0.0023
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0028 0.0101
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.02 0.0402 0.0402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Loa Loa (eye worm) RNA binding protein 0.0062 0.0103 0.0103
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0012 0.0012
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0223 0.0223
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0035 0.0035
Echinococcus granulosus jumonji domain containing 1A 0.0031 0.0035 0.0035
Echinococcus multilocularis importin 5 0.0016 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0637
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0193 0.0388 0.2193
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0007 0.0094
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0049 0.0049
Echinococcus granulosus fatty acid amide hydrolase 1 0.1002 0.2146 0.2146
Brugia malayi TAR-binding protein 0.0062 0.0103 0.0103
Echinococcus granulosus lysine specific demethylase 6a 0.0031 0.0035 0.0035
Brugia malayi beta-lactamase family protein 0.0037 0.0049 0.0049
Echinococcus multilocularis jumonji domain containing 1A 0.0031 0.0035 0.0035
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0029 0.0032 0.0948
Loa Loa (eye worm) hypothetical protein 0.078 0.1663 0.1663
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0049 0.0177
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0004 0.0004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0121 0.0649
Plasmodium vivax acyl-CoA synthetase, putative 0.007 0.0121 0.5162
Plasmodium falciparum lipid/sterol:H+ symporter 0.0024 0.002 0.0727
Schistosoma mansoni hypothetical protein 0.0062 0.0102 0.0102
Brugia malayi Patched family protein 0.0024 0.002 0.002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0032 0.0637
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0007 0.0041
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0314 0.065 0.065
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0067 0.0113 0.0113
Loa Loa (eye worm) beta-lactamase 0.0037 0.0049 0.0049
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0796 0.1698 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0152 0.3741
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0032 0.0726
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0121 0.0231 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0796 0.1698 1
Schistosoma mansoni patched 1 0.0167 0.0332 0.0332
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0007 0.0041
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0028 0.0101
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0049 0.0227
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0049 0.0177
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Plasmodium vivax importin-beta 2, putative 0.0085 0.0152 0.6546
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.0277 0.0277
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0021 0.0021
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0402 1
Echinococcus multilocularis Niemann Pick C1 protein 0.039 0.0815 0.0815
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0011
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0028 0.0151
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0032 0.0032
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0121 0.0231 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0031 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.078 0.1663 0.1663
Brugia malayi MH2 domain containing protein 0.0116 0.022 0.022
Echinococcus granulosus tissue type plasminogen activator 0.0062 0.0102 0.0102
Brugia malayi Patched family protein 0.0024 0.002 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0049 0.028
Echinococcus multilocularis lysine specific demethylase 6a 0.0031 0.0035 0.0035
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.007 0.0121 0.4984
Schistosoma mansoni tyrosine kinase 0.0522 0.1102 0.1102
Echinococcus multilocularis phd:f box containing protein 0.0031 0.0035 0.0035
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.078 0.1663 0.9795
Echinococcus granulosus importin subunit beta 1 0.0085 0.0152 0.0152
Schistosoma mansoni chromobox protein 0.0069 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0049 0.0049
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0028 0.0101
Echinococcus multilocularis protein dispatched 1 0.0191 0.0383 0.0383
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0021 0.0109
Echinococcus multilocularis microtubule associated protein 2 0.1347 0.2896 0.2896
Echinococcus granulosus cpg binding protein 0.0061 0.01 0.01
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Onchocerca volvulus 0.078 0.1663 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0028 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.022 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Loa Loa (eye worm) importin-beta domain-containing protein 0.0016 0.0003 0.0003
Brugia malayi serine/threonine-protein kinase plk-2 0.02 0.0402 0.0402
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.078 0.1663 0.9795
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0028
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0042 0.0042
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0011
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0028 0.0101
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0059 0.0338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0008 0.003
Entamoeba histolytica hypothetical protein 0.0069 0.0117 0.1242
Schistosoma mansoni topbp1 0.002 0.0011 0.0011
Schistosoma mansoni ran 0.0042 0.0059 0.0059
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.4617 1 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0031 0.0035 0.0796
Echinococcus multilocularis fatty acid amide hydrolase 1 0.1002 0.2146 0.2146
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0121 0.0231 0.1258
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0053 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0402 0.0402
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Brugia malayi Patched family protein 0.0024 0.002 0.002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0004 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0032 0.127
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0094 0.0172 0.0955
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0007 0.0096
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.018 0.018
Entamoeba histolytica hypothetical protein 0.0024 0.0021 0.0197
Echinococcus multilocularis chromobox protein 1 0.0069 0.0119 0.0119
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0032 0.0948
Brugia malayi jmjC domain containing protein 0.0031 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0071 0.0122 0.1291
Brugia malayi jmjC domain containing protein 0.0118 0.0225 0.0225
Trichomonas vaginalis ferritin, putative 0.0025 0.0023 0.0121
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0049
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0011 0.038
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0028 0.005
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0527 0.1114 0.1114
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0216 1
Schistosoma mansoni cpg binding protein 0.0061 0.01 0.01
Brugia malayi protein C24B5.3 0.0024 0.002 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0021 0.0109
Echinococcus granulosus chromobox protein 1 0.0069 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Echinococcus granulosus thioredoxin glutathione reductase 0.0085 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0035
Echinococcus multilocularis 0.0304 0.0629 0.0629
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0059 0.0059
Loa Loa (eye worm) carboxylesterase 0.078 0.1663 0.1663
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0094 0.0172 0.0955
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0035 0.0035
Brugia malayi Carboxylesterase family protein 0.078 0.1663 0.1663
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0028 0.054
Onchocerca volvulus Glucosylceramidase homolog 0.0173 0.0345 0.2024
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0032 0.0275
Brugia malayi Amidase family protein 0.0121 0.0231 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0007 0.0002
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0028 0.0101
Schistosoma mansoni tyrosine kinase 0.0314 0.065 0.065
Giardia lamblia Fructose-bisphosphate aldolase 0.044 0.0924 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0032 0.127
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0121 0.0231 0.1303
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0059 0.0337
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.0172 0.0172
Mycobacterium ulcerans bacterioferritin BfrB 0.0025 0.0023 0.0071
Brugia malayi Myosin head containing protein 0.0024 0.002 0.002
Schistosoma mansoni tyrosine kinase 0.0522 0.1102 0.1102
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.039 0.0815 0.8823
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0007 0.0007
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0121 0.0231 0.5715
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0052 0.0527
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0028 0.0028
Echinococcus multilocularis nibrin 0.002 0.0011 0.0011
Entamoeba histolytica acyl-coA synthetase, putative 0.0094 0.0172 0.1838
Schistosoma mansoni hypothetical protein 0.0161 0.0319 0.0319
Brugia malayi Patched related family protein 12 0.0024 0.002 0.002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0059 0.1318
Brugia malayi Patched family protein 0.0024 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0028 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0094 0.0172 0.0172
Onchocerca volvulus Protein patched homolog 0.0024 0.002 0.0053
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0015 0.0015
Echinococcus multilocularis tissue type plasminogen activator 0.0062 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0032 0.0124
Echinococcus granulosus RUN 0.002 0.0011 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0112 0.0551
Loa Loa (eye worm) hypothetical protein 0.078 0.1663 0.1663
Schistosoma mansoni phosphatidylserine receptor 0.0031 0.0035 0.0035
Brugia malayi Carboxylesterase family protein 0.4617 1 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0097 0.0512
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0011 0.0011
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0014 0.0177
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0121 0.0231 0.1258
Loa Loa (eye worm) TK/INSR protein kinase 0.0314 0.065 0.065
Echinococcus multilocularis expressed protein 0.0025 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0025 0.0023 0.0543
Echinococcus multilocularis fatty acid amide hydrolase 1 0.1002 0.2146 0.2146
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.0035 0.0708
Trypanosoma cruzi trypanothione reductase, putative 0.0085 0.0152 0.368
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.078 0.1663 0.1663
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0117 0.0689
Loa Loa (eye worm) doublecortin family protein 0.002 0.0011 0.0011
Brugia malayi Patched related family protein 4 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0035
Schistosoma mansoni cpg binding protein 0.0061 0.01 0.01
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0032 0.0948
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0007 0.0094
Plasmodium vivax JmjC domain containing protein 0.0031 0.0035 0.1393
Onchocerca volvulus Protein patched homolog 0.0024 0.002 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0637
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Trypanosoma brucei trypanothione reductase 0.0085 0.0152 0.374
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0011 0.0049
Mycobacterium ulcerans amidase 0.0121 0.0231 0.1303
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0011 0.0343
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0097 0.2367
Mycobacterium ulcerans bacterioferritin BfrA 0.0025 0.0023 0.0071
Plasmodium vivax SET domain protein, putative 0.0061 0.0101 0.4299
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Schistosoma mansoni jumonji domain containing protein 0.0031 0.0035 0.0035
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0028 0.054
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0032 0.0124
Echinococcus granulosus para nitrobenzyl esterase 0.078 0.1663 0.1663
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0103 0.0103
Schistosoma mansoni gliotactin 0.078 0.1663 0.1663
Schistosoma mansoni DNA ligase IV 0.002 0.0011 0.0011
Brugia malayi hypothetical protein 0.002 0.0011 0.0011
Echinococcus granulosus BC026374 protein S09 family 0.078 0.1663 0.1663
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0028 0.0028
Brugia malayi Heterochromatin protein 1 0.0069 0.0119 0.0119
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0011 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0103 0.0103
Schistosoma mansoni fatty-acid amide hydrolase 0.1002 0.2146 0.2146
Brugia malayi hypothetical protein 0.0024 0.002 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0059 0.0338
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0059 0.2616
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.0035 0.0708
Mycobacterium leprae Probable lipase LipE 0.0037 0.0049 0.0227
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0112 0.0551
Brugia malayi jmjC domain containing protein 0.0031 0.0035 0.0035
Brugia malayi Pre-SET motif family protein 0.0061 0.0101 0.0101
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0028 0.0028
Onchocerca volvulus 0.0037 0.0049 0.0234
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0007 0.0094
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0121 0.0231 0.1303
Schistosoma mansoni hypothetical protein 0.0506 0.1069 0.1069
Echinococcus multilocularis carboxylesterase 5A 0.4617 1 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0215 0.0435 0.2472
Brugia malayi Patched family protein 0.0024 0.002 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.0115 0.0218 0.0218
Plasmodium falciparum thioredoxin reductase 0.0085 0.0152 0.6544
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Brugia malayi CHE-14 protein 0.0167 0.0332 0.0332
Plasmodium vivax thioredoxin reductase, putative 0.0085 0.0152 0.6544
Loa Loa (eye worm) hypothetical protein 0.0094 0.0172 0.0172
Brugia malayi Patched family protein 0.0024 0.002 0.002
Plasmodium falciparum thioredoxin reductase 0.0029 0.0032 0.127
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Brugia malayi jmjC domain containing protein 0.0115 0.0218 0.0218
Echinococcus multilocularis acetylcholinesterase 0.4617 1 1
Echinococcus multilocularis expressed conserved protein 0.0366 0.0764 0.0764
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0121 0.0231 1
Entamoeba histolytica hypothetical protein 0.0071 0.0122 0.1291
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.022 0.022
Schistosoma mansoni hypothetical protein 0.0031 0.0035 0.0035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0101 0.0101
Plasmodium falciparum importin beta, putative 0.0085 0.0152 0.6546
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0028 0.054
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0028 0.005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0419 0.0878 0.0878
Loa Loa (eye worm) patched family protein 0.0024 0.002 0.002
Echinococcus multilocularis insulin receptor 0.0314 0.065 0.065
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0049 0.028
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.0059
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0011 0.011
Echinococcus multilocularis snurportin 1 0.0904 0.1932 0.1932
Brugia malayi DKFZp564C0469 protein 0.002 0.0011 0.0011
Plasmodium falciparum acyl-CoA synthetase 0.007 0.0121 0.5162
Onchocerca volvulus 0.0028 0.0028 0.0105
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0223 0.0223
Leishmania major GTP-binding protein, putative 0.0042 0.0059 0.14
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0396 0.0829 0.0829
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0032 0.0726
Plasmodium falciparum cysteine repeat modular protein 1 0.0062 0.0102 0.4342
Onchocerca volvulus 0.078 0.1663 1
Leishmania major hypothetical protein, conserved 0.0062 0.0102 0.2482
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.0543 0.3251
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0167 0.0332 0.0332
Loa Loa (eye worm) TK/EGFR protein kinase 0.0982 0.2102 0.2102
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.018 0.018
Brugia malayi RNA binding protein 0.0062 0.0103 0.0103
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0049 0.1165
Mycobacterium ulcerans hypothetical protein 0.0037 0.0049 0.0227
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.0172 0.0955
Brugia malayi putative amidase 0.0121 0.0231 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0345 0.2061
Echinococcus granulosus dnaJ subfamily B 0.0816 0.1741 0.1741
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0049 0.028
Brugia malayi Niemann-Pick C1 protein precursor 0.039 0.0815 0.0815
Schistosoma mansoni hypothetical protein 0.0031 0.0035 0.0035
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0028 0.0151
Plasmodium vivax patched family protein, putative 0.0024 0.002 0.0727
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0035 0.0035
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0172 0.0172
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0345 0.2061
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0101 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0366 0.2183
Mycobacterium tuberculosis Conserved protein 0.0037 0.0049 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0049 0.108
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Loa Loa (eye worm) carboxylesterase 0.4617 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0345 0.2061
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0049 0.108
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0122 0.0122
Echinococcus multilocularis cpg binding protein 0.0061 0.01 0.01
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0028 0.1176
Trichomonas vaginalis set domain proteins, putative 0.0476 0.1003 0.6023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0028 0.0101
Schistosoma mansoni hypothetical protein 0.0031 0.0035 0.0035
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0093 0.0093
Mycobacterium ulcerans amidase 0.0121 0.0231 0.1303
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0011 0.0011
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0011 0.0011
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0264 0.0543 0.0543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0109
Schistosoma mansoni topbp1 0.002 0.0011 0.0011
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0527 0.1114 0.1114
Loa Loa (eye worm) hypothetical protein 0.0094 0.0172 0.0172
Schistosoma mansoni neuroligin 3 (S09 family) 0.078 0.1663 0.1663
Echinococcus granulosus Niemann Pick C1 protein 0.0557 0.1179 0.1179
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0059 0.245
Brugia malayi protein C24B5.3 0.0024 0.002 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Onchocerca volvulus 0.0024 0.002 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0006 0.0018
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0028 0.054
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Brugia malayi Patched related family protein 10 0.0024 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0053 0.0299
Mycobacterium tuberculosis Probable reductase 0.0193 0.0388 0.2193
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Trichomonas vaginalis spcc417.12 protein, putative 0.078 0.1663 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0021 0.0365
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0402 1
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0053 0.0299
Loa Loa (eye worm) hypothetical protein 0.4617 1 1
Schistosoma mansoni apoferritin-2 0.0025 0.0023 0.0023
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Giardia lamblia Kinase, PLK 0.02 0.0402 0.4308
Loa Loa (eye worm) hypothetical protein 0.1002 0.2146 0.2146
Mycobacterium tuberculosis Conserved protein 0.0037 0.0049 0.0177
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0049 0.2038
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Loa Loa (eye worm) acetyltransferase 0.0142 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Echinococcus multilocularis acetylcholinesterase 0.4617 1 1
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.0203
Onchocerca volvulus 0.078 0.1663 1
Schistosoma mansoni acetylcholinesterase 0.078 0.1663 0.1663
Schistosoma mansoni microtubule-associated protein tau 0.1347 0.2896 0.2896
Brugia malayi Patched protein homolog 1 0.0024 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0161 0.0319 0.0319
Brugia malayi beta-lactamase family protein 0.0037 0.0049 0.0049
Onchocerca volvulus 0.0476 0.1003 0.6004
Brugia malayi glutathione reductase 0.0085 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0097 0.0512
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0121 0.0231 0.1303
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0042 0.0042
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0028 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Echinococcus granulosus fatty acid amide hydrolase 1 0.0121 0.0231 0.0231
Trypanosoma brucei polo-like protein kinase 0.02 0.0402 1
Schistosoma mansoni tyrosine kinase 0.0527 0.1114 0.1114
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0025 0.0023 0.0019
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0103 0.0103
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0035 0.0035
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0007 0.0007
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.078 0.1663 1
Loa Loa (eye worm) hypothetical protein 0.078 0.1663 0.1663
Schistosoma mansoni hypothetical protein 0.0071 0.0122 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0049 0.0049
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0094 0.0172 0.0908
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0097 0.0097
Onchocerca volvulus 0.0072 0.0126 0.0695
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0112 0.0551
Brugia malayi hypothetical protein 0.0071 0.0122 0.0122
Schistosoma mansoni tyrosine kinase 0.0314 0.065 0.065
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0028 0.0028
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0028 0.005
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0049
Echinococcus multilocularis JmjC domain containing protein 4 0.0031 0.0035 0.0035
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0032 0.0072
Mycobacterium ulcerans hypothetical protein 0.0094 0.0172 0.0955
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0059 0.1318
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0172 0.0172
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0007 0.0007
Brugia malayi hypothetical protein 0.078 0.1663 0.1663
Echinococcus multilocularis RUN 0.002 0.0011 0.0011
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.078 0.1663 0.1663
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0103 0.0103
Onchocerca volvulus 0.0024 0.002 0.0053
Echinococcus granulosus epidermal growth factor receptor 0.0527 0.1114 0.1114
Brugia malayi hypothetical protein 0.002 0.0011 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0172 0.0172
Schistosoma mansoni ferritin light chain 0.0025 0.0023 0.0023
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0007 0.0094
Echinococcus granulosus translational activator gcn1 0.0016 0.0003 0.0003
Loa Loa (eye worm) patched family protein 0.0024 0.002 0.002
Mycobacterium ulcerans amidase 0.0121 0.0231 0.1303
Schistosoma mansoni tyrosine kinase 0.0522 0.1102 0.1102
Loa Loa (eye worm) glutathione reductase 0.0085 0.0152 0.0152
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0028 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0118 0.0225 0.0225
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0059 0.245
Brugia malayi CXXC zinc finger family protein 0.0057 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Entamoeba histolytica serine/threonine protein kinase, putative 0.02 0.0402 0.4331
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0032 0.1356
Echinococcus multilocularis epidermal growth factor receptor 0.0527 0.1114 0.1114
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.007 0.0121 0.0121
Schistosoma mansoni hypothetical protein 0.0031 0.0035 0.0035
Echinococcus granulosus sterol regulatory element binding protein 0.0167 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.078 0.1663 0.1663
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0031 0.0035 0.1487
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0012 0.0012
Brugia malayi Kringle domain containing protein 0.0062 0.0102 0.0102
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0032 0.127
Loa Loa (eye worm) amidase 0.0121 0.0231 0.0231
Brugia malayi Furin-like cysteine rich region family protein 0.0982 0.2102 0.2102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0023
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.011
Trichomonas vaginalis importin beta-1, putative 0.0069 0.0117 0.0689
Brugia malayi Patched family protein 0.0024 0.002 0.002
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0011 0.0088
Echinococcus granulosus expressed conserved protein 0.0366 0.0764 0.0764
Echinococcus granulosus family S9 non peptidase ue S09 family 0.078 0.1663 0.1663
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0094 0.0172 0.0955
Onchocerca volvulus 0.0037 0.0049 0.0234
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0121 0.0231 0.2409
Brugia malayi Amidase family protein 0.0121 0.0231 0.0231
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0032 0.127
Echinococcus multilocularis translational activator gcn1 0.0016 0.0003 0.0003
Echinococcus granulosus microtubule associated protein 2 0.1347 0.2896 0.2896
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.044 0.0924 0.5546
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0049 0.0177
Mycobacterium tuberculosis Probable oxidoreductase 0.0215 0.0435 0.2472
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0028 0.1102
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0028 0.063
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0102 0.241
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0059 0.2628
Mycobacterium ulcerans acyl-CoA synthetase 0.0094 0.0172 0.0955
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0097 0.0463
Echinococcus granulosus geminin 0.0506 0.1069 0.1069
Loa Loa (eye worm) kap beta 3 protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0121 0.0231 0.1258
Loa Loa (eye worm) acetylcholinesterase 1 0.4617 1 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0059 0.2461
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0172 0.0172
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0028 0.005
Toxoplasma gondii patched family protein 0.0024 0.002 0.0777
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0028 0.005
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0402 0.2402
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.078 0.1663 0.1663
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0094 0.0172 0.0908
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0193 0.0388 0.2233
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0028 0.0101
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0121 0.0231 0.1258

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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