Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0198 | 0.5923 | 0.5923 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0068 | 0.0202 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0068 | 0.0202 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | hypothetical protein | 0.0093 | 0.1323 | 0.1144 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0198 | 0.5923 | 0.5923 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0198 | 0.5923 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0073 | 0.0424 | 0.0387 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0068 | 0.0213 | 0.5 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0198 | 0.5923 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0198 | 0.5923 | 0.5839 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0198 | 0.5923 | 0.5923 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0198 | 0.5923 | 0.5839 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0093 | 0.1323 | 0.1323 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1816 | 0.1816 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0105 | 0.1816 | 0.2821 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0198 | 0.5923 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0198 | 0.5923 | 0.5839 |
Schistosoma mansoni | nuclear hormone receptor | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0198 | 0.5923 | 0.5923 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0093 | 0.1323 | 0.196 |
Brugia malayi | nuclear receptor RXR | 0.0105 | 0.1816 | 0.1647 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0198 | 0.5923 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0093 | 0.1323 | 0.196 |
Schistosoma mansoni | voltage-gated potassium channel | 0.008 | 0.0718 | 0.0902 |
Onchocerca volvulus | 0.0198 | 0.5923 | 1 | |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0068 | 0.0202 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0068 | 0.0202 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0198 | 0.5923 | 1 |
Brugia malayi | hypothetical protein | 0.0105 | 0.1816 | 0.1647 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0105 | 0.1816 | 0.1647 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Brugia malayi | ecdysone receptor | 0.0093 | 0.1323 | 0.1144 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0073 | 0.0424 | 0.0226 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0093 | 0.1323 | 0.1323 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | hypothetical protein | 0.0093 | 0.1323 | 0.1144 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0105 | 0.1816 | 0.2821 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | nuclear receptor | 0.0093 | 0.1323 | 0.196 |
Brugia malayi | nuclear receptor NHR-67 | 0.0093 | 0.1323 | 0.1144 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0068 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0068 | 0.0202 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0068 | 0.0202 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0073 | 0.0424 | 0.0387 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0198 | 0.5923 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0068 | 0.0202 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0105 | 0.1816 | 0.1816 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0093 | 0.1323 | 0.196 |
Brugia malayi | steroid hormone receptor | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0198 | 0.5923 | 0.5839 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0068 | 0.0202 | 0.5 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0093 | 0.1323 | 0.196 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0068 | 0.0202 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0068 | 0.0213 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0198 | 0.5923 | 0.5839 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0068 | 0.0202 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0198 | 0.5923 | 0.5839 |
Schistosoma mansoni | zinc finger protein | 0.0093 | 0.1323 | 0.196 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0093 | 0.1323 | 0.196 |
Schistosoma mansoni | thyroid hormone receptor | 0.0198 | 0.5923 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0093 | 0.1323 | 0.1144 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0105 | 0.1816 | 0.1647 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0105 | 0.1816 | 0.2821 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0068 | 0.0202 | 0.0202 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0198 | 0.5923 | 0.5839 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0198 | 0.5923 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0198 | 0.5923 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0198 | 0.5923 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0198 | 0.5923 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0093 | 0.1323 | 0.196 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0198 | 0.5923 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0068 | 0.0202 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0198 | 0.5923 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | nuclear receptor | 0.0093 | 0.1323 | 0.196 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0068 | 0.0202 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0068 | 0.0202 | 0.5 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0093 | 0.1323 | 0.1323 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Brugia malayi | ecdysteroid receptor | 0.0198 | 0.5923 | 0.5839 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0093 | 0.1323 | 0.1144 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0093 | 0.1323 | 0.196 |
Brugia malayi | nuclear hormone receptor | 0.0093 | 0.1323 | 0.1144 |
Mycobacterium leprae | putative cytochrome p450 | 0.0068 | 0.0202 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0068 | 0.0202 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0198 | 0.5923 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | conserved hypotetical protein | 0.0093 | 0.1323 | 0.1144 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0093 | 0.1323 | 0.196 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0093 | 0.1323 | 0.1144 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0093 | 0.1323 | 0.196 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0093 | 0.1323 | 0.1144 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0093 | 0.1323 | 0.196 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | nuclear receptor RXR | 0.0093 | 0.1323 | 0.1144 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0291 | 1 | 1 |
Brugia malayi | tailless protein | 0.0093 | 0.1323 | 0.1144 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0198 | 0.5923 | 0.5839 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0093 | 0.1323 | 0.1144 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0198 | 0.5923 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0068 | 0.0202 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Schistosoma mansoni | nuclear hormone receptor | 0.0093 | 0.1323 | 0.196 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0068 | 0.0202 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0068 | 0.0202 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0068 | 0.0202 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0068 | 0.0202 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0068 | 0.0202 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0198 | 0.5923 | 0.5923 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0068 | 0.0202 | 0.5 |
Loa Loa (eye worm) | DR-78 | 0.0093 | 0.1323 | 0.1323 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0105 | 0.1816 | 0.2821 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0068 | 0.0202 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0198 | 0.5923 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0068 | 0.0202 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0198 | 0.5923 | 0.5923 |
Leishmania major | cytochrome p450-like protein | 0.0068 | 0.0202 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0198 | 0.5923 | 1 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0068 | 0.0202 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1816 | 0.1816 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0198 | 0.5923 | 0.5923 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1816 | 0.1816 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.008 | 0.0718 | 0.0902 |
Loa Loa (eye worm) | cytochrome P450 | 0.0068 | 0.0202 | 0.0202 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0068 | 0.0202 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0068 | 0.0202 | 0.5 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0068 | 0.0202 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0068 | 0.0202 | 0.5 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0068 | 0.0202 | 0.0202 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0198 | 0.5923 | 0.5839 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0198 | 0.5923 | 0.5839 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0093 | 0.1323 | 0.196 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0068 | 0.0202 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0068 | 0.0202 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0198 | 0.5923 | 0.5923 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0068 | 0.0202 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0068 | 0.0202 | 0.5 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0093 | 0.1323 | 0.196 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1323 | 0.1323 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0198 | 0.5923 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1816 | 0.1816 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0093 | 0.1323 | 0.196 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0198 | 0.5923 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0198 | 0.5923 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0198 | 0.5923 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0093 | 0.1323 | 0.196 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0068 | 0.0202 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0198 | 0.5923 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0198 | 0.5923 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0198 | 0.5923 | 0.5839 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0068 | 0.0202 | 0.5 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0093 | 0.1323 | 0.196 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0093 | 0.1323 | 0.196 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0073 | 0.0424 | 0.0424 |
Brugia malayi | nuclear receptor NHR-88 | 0.0093 | 0.1323 | 0.1144 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.5923 | 0.5923 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0198 | 0.5923 | 1 |
Brugia malayi | hypothetical protein | 0.0105 | 0.1816 | 0.1647 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1816 | 0.1816 |
Brugia malayi | nuclear hormone receptor | 0.0198 | 0.5923 | 0.5839 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0093 | 0.1323 | 0.1144 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 12 % | Inhibition of IL-1beta-induced arachidonic acid release in human SW982 cells using [3H]AA at 10 uM by liquid scintillation counting | ChEMBL. | 25152071 |
Inhibition (binding) | = 26 % | Inhibition of human recombinant GIVA cPLA2 at 1 uM in vitro vesicle assay | ChEMBL. | 25152071 |
Inhibition (binding) | = 40 % | Inhibition of human recombinant GIVA cPLA2 using 400 uM Triton X-100/97 uM PAPC/1.8 uM 14C-labeled PAPC/3uM PIP2 substrate mixedmicelles at 1 uM | ChEMBL. | 25152071 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.