Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | rrna methyltransferase 3 | 0.0032 | 0.003 | 0.0099 |
Treponema pallidum | cell division protein (ftsJ) | 0.0032 | 0.003 | 0.5 |
Toxoplasma gondii | subtilisin SUB11 | 0.0092 | 0.0145 | 1 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0585 | 0.109 | 0.5942 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0038 | 0.0041 | 0.2822 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0026 | 0.0017 | 0.0017 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Toxoplasma gondii | subtilisin SUB2 | 0.0092 | 0.0145 | 1 |
Schistosoma mansoni | furin-1 (S08 family) | 0.0939 | 0.1769 | 0.5141 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | rrna methyltransferase 3 | 0.0032 | 0.003 | 0.0078 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0092 | 0.0145 | 0.0646 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0679 | 0.1271 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0418 | 0.0769 | 0.223 |
Trichomonas vaginalis | hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Plasmodium falciparum | subtilisin-like protease 3 | 0.0092 | 0.0145 | 0.0142 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Plasmodium falciparum | subtilisin-like protease 1 | 0.0092 | 0.0145 | 0.0142 |
Mycobacterium ulcerans | proline rich membrane-anchored mycosin MycP5 | 0.0092 | 0.0145 | 0.0145 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Brugia malayi | proprotein convertase 2 | 0.1432 | 0.2714 | 0.7894 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Brugia malayi | Trypsin family protein | 0.0036 | 0.0038 | 0.011 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.002 | 0.002 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0021 | 0.0008 | 0.0007 |
Brugia malayi | Protein kinase domain containing protein | 0.0018 | 0.0003 | 0.0008 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0026 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | subtilase | 0.0092 | 0.0145 | 0.0413 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0679 | 0.1271 | 1 |
Toxoplasma gondii | ribosomal RNA large subunit methyltransferase J protein | 0.0032 | 0.003 | 0.2063 |
Trichomonas vaginalis | neuroendocrine convertase 2 precursor, putative | 0.0493 | 0.0913 | 0.495 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Onchocerca volvulus | 0.0024 | 0.0014 | 0.0372 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Schistosoma mansoni | tyrosine kinase | 0.0321 | 0.0585 | 0.1693 |
Plasmodium vivax | ribosomal RNA large subunit methyltransferase J, putative | 0.0032 | 0.003 | 0.0027 |
Onchocerca volvulus | 0.0036 | 0.0038 | 0.1205 | |
Trypanosoma brucei | serine peptidase, clan SB, family S8-like protein | 0.0092 | 0.0145 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | peptidase s8 s53 subtilisin kexin sedolisin | 0.0092 | 0.0145 | 0.0413 |
Toxoplasma gondii | subtilisin SUB9 | 0.0092 | 0.0145 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0027 | 0.002 | 0.1357 |
Plasmodium falciparum | ribosomal RNA methyltransferase, putative | 0.0032 | 0.003 | 0.0027 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | rho-associated protein kinase 1 | 0.017 | 0.0294 | 0.0846 |
Onchocerca volvulus | 0.0036 | 0.0038 | 0.1205 | |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0321 | 0.0585 | 0.2145 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0027 | 0.002 | 0.1357 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Plasmodium vivax | subtilisin-like protease 2, putative | 0.0092 | 0.0145 | 0.0142 |
Toxoplasma gondii | subtilisin SUB4 | 0.0092 | 0.0145 | 1 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0585 | 0.109 | 0.5942 |
Plasmodium falciparum | subtilisin-like protease 2 | 0.0092 | 0.0145 | 0.0142 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Onchocerca volvulus | 0.0036 | 0.0038 | 0.1205 | |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.5231 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0092 | 0.0145 | 0.0646 |
Toxoplasma gondii | subtilisin SUB1 | 0.0092 | 0.0145 | 1 |
Loa Loa (eye worm) | proprotein convertase 2 | 0.0585 | 0.109 | 0.3165 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0027 | 0.002 | 0.0017 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0038 | 0.011 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0036 | 0.0038 | 0.0129 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0038 | 0.0041 | 0.0041 |
Brugia malayi | Kringle domain containing protein | 0.0018 | 0.0003 | 0.0008 |
Onchocerca volvulus | 0.0036 | 0.0038 | 0.1205 | |
Toxoplasma gondii | subtilisin SUB10 | 0.0092 | 0.0145 | 1 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0046 | 0.0056 | 0.1835 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Onchocerca volvulus | 0.0066 | 0.0096 | 0.3187 | |
Trypanosoma brucei | 2'-O-ribose RNA methyltransferase SPB1 homolog | 0.0032 | 0.003 | 0.0953 |
Mycobacterium tuberculosis | Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) | 0.0092 | 0.0145 | 0.0142 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0076 | 0.0114 | 0.0407 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.005 | 0.0138 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0026 | 0.0017 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.003 | 0.0078 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0167 | 0.0289 | 0.1454 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0036 | 0.0038 | 0.0129 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0962 | 0.1814 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Onchocerca volvulus | 0.0036 | 0.0038 | 0.1205 | |
Entamoeba histolytica | fatty acid elongase, putative | 0.0679 | 0.1271 | 1 |
Onchocerca volvulus | 0.0075 | 0.0113 | 0.3766 | |
Loa Loa (eye worm) | ribosomal RNA methyltransferase | 0.0032 | 0.003 | 0.0078 |
Loa Loa (eye worm) | trypsin family protein | 0.0036 | 0.0038 | 0.0102 |
Mycobacterium ulcerans | membrane-anchored mycosin MycP3 | 0.0092 | 0.0145 | 0.0145 |
Echinococcus multilocularis | Peptidase S8 S53, subtilisin kexin sedolisin | 0.0092 | 0.0145 | 0.0524 |
Onchocerca volvulus | Putative ribosomal RNA methyltransferase | 0.0032 | 0.003 | 0.0922 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0027 | 0.002 | 0.1394 |
Mycobacterium tuberculosis | Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) | 0.0092 | 0.0145 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0666 | 0.1931 |
Echinococcus multilocularis | Furin 1 | 0.0585 | 0.109 | 0.401 |
Echinococcus multilocularis | Mastin | 0.0076 | 0.0114 | 0.0407 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0025 | 0.0016 | 0.0012 |
Brugia malayi | Will die slowly protein | 0.0066 | 0.0096 | 0.0278 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0021 | 0.0008 | 0.0007 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0024 | 0.0014 | 0.0032 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0585 | 0.109 | 0.5942 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0018 | 0.0015 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0036 | 0.0038 | 0.011 |
Onchocerca volvulus | 0.0044 | 0.0053 | 0.1731 | |
Brugia malayi | Trypsin family protein | 0.0036 | 0.0038 | 0.011 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0036 | 0.0038 | 0.0129 |
Echinococcus multilocularis | enteropeptidase | 0.0076 | 0.0114 | 0.0407 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0026 | 0.0017 | 0.0017 |
Toxoplasma gondii | subtilisin SUB7 | 0.0092 | 0.0145 | 1 |
Toxoplasma gondii | subtilisin SUB5 | 0.0092 | 0.0145 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0321 | 0.0585 | 0.1693 |
Mycobacterium ulcerans | polyketide synthase | 0.0026 | 0.0017 | 0.0017 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0962 | 0.1814 | 1 |
Brugia malayi | Subtilase family protein | 0.0092 | 0.0145 | 0.0422 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0014 | 0.004 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.0092 | 0.0145 | 1 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0036 | 0.0038 | 0.011 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0018 | 0.1032 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0096 | 0.027 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0036 | 0.0038 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0018 | 0.0043 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0321 | 0.0585 | 0.1693 |
Plasmodium vivax | FtsJ-like methyltransferase, putative | 0.0032 | 0.003 | 0.0027 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.0167 | 0.0289 | 0.0833 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0018 | 0.1227 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.0092 | 0.0145 | 1 |
Mycobacterium ulcerans | membrane-anchored serine protease (mycosin), MycP4 | 0.0092 | 0.0145 | 0.0145 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0026 | 0.0017 | 0.1147 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0025 | 0.0016 | 0.0012 |
Echinococcus multilocularis | ribosomal RNA large subunit methyltransferase | 0.0032 | 0.003 | 0.0099 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.5231 | 1 | 1 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.5231 | 1 | 1 |
Leishmania major | subtilisin-like serine peptidase | 0.0092 | 0.0145 | 1 |
Echinococcus granulosus | Furin 1 | 0.0585 | 0.109 | 0.3165 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Onchocerca volvulus | 0.0092 | 0.0145 | 0.4887 | |
Loa Loa (eye worm) | WD40 repeat protein | 0.0066 | 0.0096 | 0.027 |
Brugia malayi | Membrane-bound transcription factor site-1 protease precursor | 0.0092 | 0.0145 | 0.0422 |
Schistosoma mansoni | subfamily S8B non-peptidase homologue (S08 family) | 0.0585 | 0.109 | 0.3165 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0075 | 0.0112 | 0.0462 |
Mycobacterium tuberculosis | Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) | 0.0092 | 0.0145 | 0.0142 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0018 | 0.1032 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0038 | 0.0038 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0026 | 0.0017 | 0.0017 |
Giardia lamblia | Furin precursor putative serine protease | 0.0493 | 0.0913 | 1 |
Trypanosoma brucei | subtilisin peptidase | 0.0092 | 0.0145 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0145 | 0.0413 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Echinococcus multilocularis | rho associated protein kinase | 0.017 | 0.0294 | 0.1072 |
Mycobacterium ulcerans | thioesterase TesA | 0.0021 | 0.0009 | 0.0008 |
Onchocerca volvulus | 0.0036 | 0.0038 | 0.1205 | |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.5231 | 1 | 1 |
Mycobacterium leprae | PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) | 0.0092 | 0.0145 | 1 |
Brugia malayi | Trypsin family protein | 0.0036 | 0.0038 | 0.011 |
Giardia lamblia | High cysteine membrane protein Group 2 | 0.0453 | 0.0836 | 0.9131 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | Mastin | 0.0076 | 0.0114 | 0.0321 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Toxoplasma gondii | subtilisin SUB8 | 0.0092 | 0.0145 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0012 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0092 | 0.0145 | 0.0646 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0026 | 0.0017 | 0.0049 |
Echinococcus granulosus | protein will die slowly | 0.0066 | 0.0096 | 0.027 |
Brugia malayi | celfurPC protein | 0.1392 | 0.2637 | 0.7671 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0018 | 0.0051 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0024 | 0.0014 | 0.0011 |
Echinococcus multilocularis | 0.1392 | 0.2637 | 0.9717 | |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0026 | 0.0017 | 0.1147 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0027 | 0.002 | 0.1357 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0038 | 0.0041 | 0.0038 |
Echinococcus multilocularis | membrane bound transcription factor site 1 | 0.0092 | 0.0145 | 0.0524 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0021 | 0.0008 | 0.0485 |
Mycobacterium tuberculosis | Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) | 0.0092 | 0.0145 | 0.0142 |
Plasmodium vivax | subtilisin-like protease 1 | 0.0092 | 0.0145 | 0.0142 |
Brugia malayi | rRNA methyltransferase | 0.0032 | 0.003 | 0.0086 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0021 | 0.0009 | 0.0583 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Toxoplasma gondii | subtilisin SUB12 | 0.0092 | 0.0145 | 1 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.002 | 0.0017 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0092 | 0.0145 | 0.0646 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0585 | 0.109 | 0.5942 |
Echinococcus granulosus | enteropeptidase | 0.0076 | 0.0114 | 0.0321 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0036 | 0.0038 | 0.0102 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0018 | 0.0003 | 0.0213 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0021 | 0.0009 | 0.0006 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0038 | 0.0041 | 0.0038 |
Trichomonas vaginalis | leucine-rich repeat protein, BspA family | 0.0418 | 0.0769 | 0.4142 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0021 | 0.0008 | 0.0005 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.1809 | 0.3438 | 1 |
Trypanosoma cruzi | serine peptidase, clan SB, family S8-like protein | 0.0092 | 0.0145 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0036 | 0.0038 | 0.0102 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0027 | 0.002 | 0.0017 |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.172 | 0.3268 | 0.9505 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0048 | 0.0061 | 0.0177 |
Trichomonas vaginalis | WD repeat domain, putative | 0.0066 | 0.0096 | 0.0369 |
Trichomonas vaginalis | proprotein convertase subtilisin/kexin type, putative | 0.0493 | 0.0913 | 0.495 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | putative ribosomal RNA methyltransferase/cell division FtsJ protein | 0.0032 | 0.003 | 0.0078 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Onchocerca volvulus | 0.0169 | 0.0293 | 0.9976 | |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0679 | 0.1271 | 1 |
Toxoplasma gondii | subtilisin SUB6 | 0.0092 | 0.0145 | 1 |
Schistosoma mansoni | cell division protein ftsj | 0.0032 | 0.003 | 0.0078 |
Loa Loa (eye worm) | AGC/DMPK/ROCK protein kinase | 0.0527 | 0.098 | 0.2843 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0321 | 0.0585 | 0.17 |
Toxoplasma gondii | kringle domain-containing protein | 0.0018 | 0.0003 | 0.0217 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Echinococcus granulosus | furin | 0.1809 | 0.3438 | 1 |
Mycobacterium ulcerans | thioesterase | 0.0021 | 0.0009 | 0.0008 |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.1432 | 0.2714 | 0.7892 |
Mycobacterium leprae | Possible secreted protease | 0.0092 | 0.0145 | 1 |
Onchocerca volvulus | 0.017 | 0.0294 | 1 | |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.1432 | 0.2714 | 1 |
Mycobacterium ulcerans | polyketide synthase | 0.0027 | 0.002 | 0.002 |
Schistosoma mansoni | site-1 peptidase (S08 family) | 0.0092 | 0.0145 | 0.0413 |
Brugia malayi | endoprotease bli-4 precursor | 0.1809 | 0.3438 | 1 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0679 | 0.1271 | 1 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.5231 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0418 | 0.0769 | 0.4142 |
Brugia malayi | Hypothetical subtilase-type proteinase F21H12.6 in chromosome II | 0.0092 | 0.0145 | 0.0422 |
Brugia malayi | Protein kinase domain containing protein | 0.0527 | 0.098 | 0.2849 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.5231 | 1 | 0.5 |
Brugia malayi | ribosomal RNA methyltransferase | 0.0032 | 0.003 | 0.0086 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0585 | 0.109 | 0.5942 |
Echinococcus multilocularis | protein will die slowly | 0.0066 | 0.0096 | 0.0342 |
Schistosoma mansoni | site-1 peptidase (S08 family) | 0.0092 | 0.0145 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0922 | 0.1736 | 0.5046 |
Plasmodium falciparum | large subunit rRNA methyltransferase, putative | 0.0032 | 0.003 | 0.0027 |
Schistosoma mansoni | serine/threonine protein kinase | 0.017 | 0.0294 | 0.0846 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0026 | 0.0017 | 0.0014 |
Mycobacterium leprae | PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) | 0.0092 | 0.0145 | 1 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0076 | 0.0114 | 0.0321 |
Schistosoma mansoni | tripeptidyl-peptidase II (S08 family) | 0.0092 | 0.0145 | 0.0413 |
Brugia malayi | Trypsin family protein | 0.0036 | 0.0038 | 0.011 |
Schistosoma mansoni | ribosomal RNA methyltransferase | 0.0032 | 0.003 | 0.0078 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.0962 | 0.1814 | 0.5273 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0585 | 0.109 | 0.5942 |
Loa Loa (eye worm) | fatty acid synthase | 0.0025 | 0.0017 | 0.0039 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0027 | 0.002 | 0.002 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0026 | 0.0017 | 0.0014 |
Echinococcus granulosus | membrane bound transcription factor site 1 | 0.0092 | 0.0145 | 0.0413 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.1809 | 0.3438 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0018 | 0.0015 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0076 | 0.0114 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0018 | 0.1032 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0092 | 0.0145 | 0.0646 |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.0962 | 0.1814 | 0.6681 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0038 | 0.0102 |
Plasmodium vivax | subtilisin-like serine protease, putative | 0.0092 | 0.0145 | 0.0142 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0092 | 0.0145 | 0.0646 |
Toxoplasma gondii | ribosomal RNA methyltransferase (FtsJ) family protein | 0.0032 | 0.003 | 0.2063 |
Trypanosoma cruzi | subtilisin peptidase | 0.0092 | 0.0145 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0036 | 0.0038 | 0.0102 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.5231 | 1 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.1809 | 0.3438 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | = 190 uM | Cytotoxicity against mock-infected human MT4 cells after 5 days by MTT assay | ChEMBL. | 25089812 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.