Detailed information for compound 929750

Basic information

Technical information
  • TDR Targets ID: 929750
  • Name: propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-5- (4-bromophenyl)-3-hydroxypent-1-enyl]-3,5-dih ydroxycyclopentyl]hept-5-enoate
  • MW: 509.473 | Formula: C26H37BrO5
  • H donors: 3 H acceptors: 4 LogP: 4.51 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(OC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@H]([C@@H]1/C=C/[C@@H](CCc1ccc(cc1)Br)O)O)C
  • InChi: 1S/C26H37BrO5/c1-18(2)32-26(31)8-6-4-3-5-7-22-23(25(30)17-24(22)29)16-15-21(28)14-11-19-9-12-20(27)13-10-19/h3,5,9-10,12-13,15-16,18,21-25,28-30H,4,6-8,11,14,17H2,1-2H3/b5-3-,16-15+/t21-,22-,23-,24+,25-/m1/s1
  • InChiKey: WTMDDBWZLIBQHN-CHYXWDFWSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • isopropyl (Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-5-(4-bromophenyl)-3-hydroxy-pent-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate
  • (Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-5-(4-bromophenyl)-3-hydroxypent-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid isopropyl ester
  • (Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-5-(4-bromophenyl)-3-hydroxy-pent-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoic acid isopropyl ester
  • propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-5-(4-bromophenyl)-3-hydroxy-pent-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni notch 0.0046 0.0003 0.0001
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.1454 0.4261 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Brugia malayi Doublecortin family protein 0.0047 0.0006 0.0002
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0065 0.0062 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0062 0.0061
Brugia malayi Protein kinase domain containing protein 0.01 0.0167 0.0164
Plasmodium falciparum cysteine repeat modular protein 1 0.0146 0.0305 1
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0227 0.0225
Leishmania major hypothetical protein, conserved 0.0132 0.0264 0.0603
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0007 0.0007
Brugia malayi serine/threonine-protein kinase 6 0.012 0.0227 0.0224
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1198 0.3488 0.3485
Onchocerca volvulus 0.0047 0.0006 0.0017
Plasmodium vivax serine/threonine protein kinase 6, putative 0.012 0.0227 0.7388
Loa Loa (eye worm) TK/INSR protein kinase 0.1192 0.347 0.347
Echinococcus multilocularis ephrin type A receptor 4 A 0.0096 0.0155 0.0152
Trypanosoma brucei aurora B kinase 0.012 0.0227 0.0516
Loa Loa (eye worm) AUR protein kinase 0.012 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.012 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0063 0.0055 0.0055
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.012 0.0228 0.0228
Loa Loa (eye worm) hypothetical protein 0.0075 0.0091 0.0091
Echinococcus multilocularis dual specificity 0.0096 0.0154 0.015
Echinococcus granulosus aurora kinase A 0.012 0.0227 0.0224
Loa Loa (eye worm) hypothetical protein 0.0155 0.0333 0.0333
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0268 0.0676 0.0675
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.0611 0.5
Schistosoma mansoni hypothetical protein 0.0046 0.0003 0.0001
Schistosoma mansoni lipoxygenase 0.0047 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0057 0.0038 0.0038
Loa Loa (eye worm) AUR protein kinase 0.012 0.0227 0.0227
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0146 0.0305 1
Loa Loa (eye worm) AUR protein kinase 0.012 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Echinococcus granulosus tissue type plasminogen activator 0.0132 0.0264 0.0261
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0065 0.0062 0.0062
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.0541 0.15 0.3508
Echinococcus multilocularis lipoxygenase domain containing protein 0.0047 0.0006 0.0002
Brugia malayi Protein kinase domain containing protein 0.0065 0.0062 0.0059
Schistosoma mansoni tyrosine kinase 0.1807 0.5329 0.5328
Loa Loa (eye worm) hypothetical protein 0.0093 0.0146 0.0146
Toxoplasma gondii calcium binding egf domain-containing protein 0.012 0.0228 0.0527
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0024
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1198 0.3488 0.3485
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0096 0.0154 0.0344
Trichomonas vaginalis AGC family protein kinase 0.012 0.0227 1
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0541 0.15 0.3508
Plasmodium falciparum protein kinase 5 0.0047 0.0007 0.0059
Plasmodium falciparum serine/threonine protein kinase, putative 0.012 0.0227 0.7388
Brugia malayi Protein kinase domain containing protein 0.0047 0.0007 0.0004
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0533 0.1475 0.1475
Echinococcus multilocularis dual specificity protein kinase clk2 0.0065 0.0062 0.0059
Echinococcus granulosus hypothetical protein 0.0063 0.0055 0.0052
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0047 0.0007 0.001
Loa Loa (eye worm) Notch2 0.0046 0.0003 0.0003
Brugia malayi hypothetical protein 0.0047 0.0006 0.0002
Schistosoma mansoni tyrosine kinase 0.1832 0.5405 0.5405
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0007 0.0004
Trichomonas vaginalis AGC family protein kinase 0.012 0.0227 1
Trichomonas vaginalis AGC family protein kinase 0.012 0.0227 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0044 0.0044
Echinococcus granulosus epidermal growth factor receptor 0.3351 1 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0228 0.0228
Trypanosoma cruzi aurora B kinase, putative 0.012 0.0227 0.0516
Echinococcus multilocularis insulin receptor 0.1192 0.347 0.3468
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Toxoplasma gondii kringle domain-containing protein 0.0146 0.0305 0.0709
Loa Loa (eye worm) hypothetical protein 0.0093 0.0146 0.0146
Entamoeba histolytica protein kinase domain containing protein 0.012 0.0227 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1832 0.5405 0.5404
Onchocerca volvulus 0.0465 0.1271 0.9215
Schistosoma mansoni notch 0.0046 0.0003 0.0001
Giardia lamblia Aurora kinase 0.012 0.0227 1
Schistosoma mansoni tyrosine kinase 0.0049 0.0013 0.0011
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0096 0.0154 0.0154
Echinococcus granulosus insulin receptor 0.1192 0.347 0.3468
Schistosoma mansoni tyrosine kinase 0.1192 0.347 0.3468
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0541 0.15 0.3508
Onchocerca volvulus 0.0057 0.0038 0.0251
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0065 0.0062 0.0139
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0096 0.0154 0.0344
Schistosoma mansoni fructose-16-bisphosphatase-related 0.1454 0.4261 0.4261
Plasmodium vivax protein kinase Crk2 0.0047 0.0007 0.0059
Schistosoma mansoni polycystin 1-related 0.0047 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0132 0.0264 0.0264
Schistosoma mansoni hypothetical protein 0.0046 0.0003 0.0001
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.012 0.0227 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0065 0.0062 0.0129
Loa Loa (eye worm) hypothetical protein 0.012 0.0228 0.0228
Schistosoma mansoni hypothetical protein 0.0047 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Toxoplasma gondii calcium binding egf domain-containing protein 0.012 0.0228 0.0527
Leishmania major 0.1454 0.4261 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Schistosoma mansoni notch 0.0046 0.0003 0.0001
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0007 0.0184
Onchocerca volvulus Arrow homolog 0.012 0.0228 0.1633
Schistosoma mansoni laminin gamma-3 chain 0.0046 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0024
Entamoeba histolytica protein kinase, putative 0.0096 0.0154 0.666
Onchocerca volvulus Tyrosine kinase homolog 0.0501 0.1379 1
Loa Loa (eye worm) hypothetical protein 0.0268 0.0676 0.0676
Echinococcus multilocularis Polycystic kidney disease protein 0.0047 0.0006 0.0002
Echinococcus multilocularis Tolloid protein 1 0.012 0.0228 0.0225
Schistosoma mansoni ephrin receptor 0.0082 0.0114 0.0112
Echinococcus multilocularis fibrillin 1 0.012 0.0228 0.0225
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0268 0.0676 0.0673
Brugia malayi serine/threonine protein kinase 6 0.012 0.0227 0.0224
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0065 0.0062 0.0129
Entamoeba histolytica protein kinase , putative 0.012 0.0227 1
Echinococcus granulosus roundabout 2 0.0059 0.0042 0.0039
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0047 0.0006 0.0006
Leishmania major protein kinase, putative 0.0065 0.0062 0.0129
Echinococcus granulosus epidermal growth factor receptor 0.1832 0.5405 0.5404
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Loa Loa (eye worm) notch protein 0.0046 0.0003 0.0003
Echinococcus granulosus RUN 0.0047 0.0006 0.0002
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0047 0.0007 0.0007
Schistosoma mansoni protein kinase 0.012 0.0227 0.0225
Echinococcus multilocularis roundabout 2 0.0059 0.0042 0.0039
Echinococcus multilocularis 0.1034 0.2992 0.299
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0062 0.0061
Brugia malayi ephrin receptor 1 precursor 0.0052 0.0022 0.0019
Loa Loa (eye worm) bone morphogenetic protein 1b 0.012 0.0228 0.0228
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.0541 0.15 0.3514
Schistosoma mansoni hypothetical protein 0.0046 0.0003 0.0001
Brugia malayi hypothetical protein 0.0128 0.0253 0.025
Schistosoma mansoni rab6-interacting 0.0047 0.0006 0.0004
Echinococcus multilocularis 0.0063 0.0055 0.0052
Loa Loa (eye worm) TK/ROR protein kinase 0.0168 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0096 0.0154 0.666
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0096 0.0154 0.0344
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.1454 0.4261 0.4261
Trypanosoma cruzi hypothetical protein, conserved 0.0132 0.0264 0.0603
Echinococcus granulosus laminin 0.012 0.0228 0.0225
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Echinococcus granulosus cyclin dependent kinase 5 0.0047 0.0007 0.0004
Loa Loa (eye worm) TK/EPH protein kinase 0.0098 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Echinococcus multilocularis cyclin dependent kinase 0.0047 0.0007 0.0004
Schistosoma mansoni tyrosine kinase 0.1832 0.5405 0.5405
Brugia malayi cell division control protein 2 homolog 0.0047 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Brugia malayi fructose-1,6-bisphosphatase 0.1454 0.4261 0.426
Entamoeba histolytica protein kinase, putative 0.012 0.0227 1
Echinococcus granulosus Polycystic kidney disease protein 0.0047 0.0006 0.0002
Onchocerca volvulus 0.0047 0.0006 0.0017
Schistosoma mansoni septate junction protein 0.0046 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0046 0.0003 0.0001
Schistosoma mansoni notch 0.0046 0.0003 0.0001
Schistosoma mansoni tyrosine kinase 0.1807 0.5329 0.5328
Echinococcus granulosus ephrin type A receptor 4 A 0.0096 0.0155 0.0152
Echinococcus multilocularis RUN 0.0047 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0059 0.0044 0.0044
Trichomonas vaginalis AGC family protein kinase 0.012 0.0227 1
Brugia malayi Protein kinase domain containing protein 0.0157 0.034 0.0337
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.012 0.0227 0.0224
Echinococcus granulosus Tolloid protein 1 0.012 0.0228 0.0225
Brugia malayi Calcium binding EGF domain containing protein 0.012 0.0228 0.0225
Toxoplasma gondii fructose-bisphospatase I 0.0541 0.15 0.3514
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.012 0.0227 1
Brugia malayi Protein kinase domain containing protein 0.0096 0.0154 0.015
Leishmania major protein kinase, putative 0.012 0.0227 0.0516
Loa Loa (eye worm) hypothetical protein 0.012 0.0228 0.0228
Schistosoma mansoni hypothetical protein 0.0046 0.0003 0.0001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0047 0.0006 0.0002
Plasmodium vivax serine/threonine kinase-1, putative 0.0065 0.0062 0.1893
Plasmodium falciparum protein serine/threonine kinase-1 0.0065 0.0062 0.1893
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.012 0.0228 0.0228
Brugia malayi Kringle domain containing protein 0.0132 0.0264 0.0261
Toxoplasma gondii fructose-bisphospatase II 0.1454 0.4261 1
Schistosoma mansoni loxhd1 0.0047 0.0006 0.0004
Brugia malayi GCC2 and GCC3 family protein 0.0059 0.0044 0.0041
Schistosoma mansoni egf-like domain protein 0.012 0.0228 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0059 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Loa Loa (eye worm) doublecortin family protein 0.0047 0.0006 0.0006
Giardia lamblia Kinase, CMGC CLK 0.0065 0.0062 0.2641
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.1454 0.4261 0.426
Toxoplasma gondii aurora kinase 0.012 0.0227 0.0525
Leishmania major protein kinase, putative 0.0065 0.0062 0.0129
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.012 0.0227 1
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0065 0.0062 0.0129
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.1454 0.4261 1
Echinococcus multilocularis cyclin dependent kinase 5 0.0047 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0128 0.0253 0.0253
Schistosoma mansoni tyrosine kinase 0.3351 1 1
Echinococcus multilocularis laminin 0.012 0.0228 0.0225
Brugia malayi serine/threonine kinase 12 0.012 0.0227 0.0224
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0007 0.0004
Schistosoma mansoni slit 0.0046 0.0003 0.0001
Brugia malayi Protein kinase domain containing protein 0.1192 0.347 0.3468
Schistosoma mansoni tyrosine kinase 0.1192 0.347 0.3468
Echinococcus granulosus dual specificity protein kinase clk2 0.0065 0.0062 0.0059
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0268 0.0676 0.0673
Brugia malayi hypothetical protein 0.0047 0.0006 0.0002
Echinococcus granulosus cyclin dependent kinase 0.0047 0.0007 0.0004
Schistosoma mansoni tyrosine kinase 0.1807 0.5329 0.5328
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.012 0.0228 0.0225
Echinococcus granulosus cyclin dependent kinase 1 0.0047 0.0007 0.0004
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0046 0.0003 0.0001
Echinococcus granulosus lipoxygenase domain containing protein 0.0047 0.0006 0.0002
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0047 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0003 0.0003
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0065 0.0062 0.0129
Schistosoma mansoni hypothetical protein 0.0132 0.0264 0.0262
Schistosoma mansoni cell adhesion molecule 0.0048 0.001 0.0009
Schistosoma mansoni notch 0.0046 0.0003 0.0001
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.012 0.0228 0.0226
Trypanosoma brucei fructose-1,6-bisphosphatase 0.1454 0.4261 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0006 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0154 0.666
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0007 0.0184
Onchocerca volvulus 0.0132 0.0264 0.1895
Schistosoma mansoni cell polarity protein 0.0046 0.0003 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0062 0.2502
Schistosoma mansoni rab6-interacting 0.0047 0.0006 0.0004
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0096 0.0154 0.0344
Schistosoma mansoni hypothetical protein 0.0046 0.0003 0.0001
Onchocerca volvulus 0.0059 0.0044 0.03
Loa Loa (eye worm) hypothetical protein 0.0128 0.0253 0.0253
Echinococcus granulosus serine:threonine protein kinase 12 B 0.012 0.0227 0.0224
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.012 0.0227 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0533 0.1475 0.1472
Echinococcus multilocularis epidermal growth factor receptor 0.1832 0.5405 0.5404
Echinococcus granulosus fructose 16 bisphosphatase 1 0.1454 0.4261 0.426
Loa Loa (eye worm) TK/EGFR protein kinase 0.3351 1 1
Entamoeba histolytica hypothetical protein 0.0096 0.0154 0.666
Echinococcus multilocularis tissue type plasminogen activator 0.0132 0.0264 0.0261
Brugia malayi Fibulin-1 precursor 0.012 0.0228 0.0225
Echinococcus granulosus lipoxygenase domain containing protein 0.0047 0.0006 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0154 0.0152
Schistosoma mansoni notch 0.0046 0.0003 0.0001
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0065 0.0062 0.0129
Echinococcus multilocularis epidermal growth factor receptor 0.3351 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0007 0.0006
Echinococcus multilocularis aurora kinase A 0.012 0.0227 0.0224
Echinococcus granulosus dual specificity 0.0096 0.0154 0.015
Schistosoma mansoni hypothetical protein 0.0046 0.0003 0.0001

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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