Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0072 | 0.0242 | 0.0242 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.028 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0072 | 0.0242 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.028 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.028 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.028 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.028 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0072 | 0.0242 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0177 | 0.5169 | 0.5049 |
Schistosoma mansoni | neuropeptide receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.5529 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.5529 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.028 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.028 | 1 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0072 | 0.0242 | 0.0242 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0242 | 0.0438 |
Echinococcus multilocularis | allatostatin A receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.028 | 1 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.5169 | 0.5169 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0177 | 0.5169 | 0.5169 |
Schistosoma mansoni | myosin xvIII | 0.028 | 1 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.028 | 1 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.028 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0072 | 0.0242 | 0.5 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0242 | 0.0438 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.028 | 1 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.028 | 1 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.028 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.028 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Brugia malayi | GnHR receptor homolog | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0072 | 0.0242 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.028 | 1 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Echinococcus granulosus | g protein coupled receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0177 | 0.5169 | 0.5169 |
Giardia lamblia | Cathepsin B precursor | 0.0067 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.028 | 1 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.028 | 1 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0177 | 0.5169 | 0.5049 |
Brugia malayi | G-protein coupled receptor | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.028 | 1 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.5529 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0072 | 0.0242 | 0.0242 |
Schistosoma mansoni | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0072 | 0.0242 | 0.0242 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.028 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0072 | 0.0242 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0242 | 0.0438 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.028 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0163 | 0.4493 | 0.8125 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Schistosoma mansoni | neuropeptide receptor | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.028 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0072 | 0.0242 | 0.0242 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.028 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0177 | 0.5169 | 0.5169 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Brugia malayi | larval opioid receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.028 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0072 | 0.0242 | 0.0242 |
Echinococcus multilocularis | somatostatin receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0242 | 0.0438 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.028 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0072 | 0.0242 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.028 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0177 | 0.5169 | 0.9349 |
Schistosoma mansoni | histamine h1 receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.028 | 1 | 1 |
Brugia malayi | RE15519p | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0177 | 0.5169 | 0.5049 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.5529 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0072 | 0.0242 | 0.5 |
Echinococcus granulosus | somatostatin receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Brugia malayi | Serotonin receptor | 0.028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0177 | 0.5169 | 0.5169 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.028 | 1 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.028 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.028 | 1 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.028 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.028 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.028 | 1 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.028 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0185 | 0.5529 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0067 | 0 | 0.5 |
Echinococcus granulosus | allatostatin A receptor | 0.028 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0067 | 0 | 0.5 |
Brugia malayi | G protein-coupled receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.028 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0072 | 0.0242 | 0.5 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.5529 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.028 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.0242 | 0.0438 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.5529 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.028 | 1 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Schistosoma mansoni | adenoreceptor | 0.028 | 1 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.028 | 1 | 1 |
Brugia malayi | Dopamine receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.028 | 1 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.028 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0072 | 0.0242 | 0.0242 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.028 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0072 | 0.0242 | 0.5 |
Echinococcus granulosus | serotonin receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0177 | 0.5169 | 0.5049 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0072 | 0.0242 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.028 | 1 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.028 | 1 | 1 | |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.028 | 1 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.028 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0072 | 0.0242 | 0.0438 |
Echinococcus multilocularis | cathepsin b | 0.0177 | 0.5169 | 0.5049 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.028 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.028 | 1 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.028 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0242 | 0.0242 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.013 | 0.2972 | 0.5375 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.028 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Echinococcus multilocularis | g-protein coupled receptor | 0.028 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.028 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.028 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.028 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0072 | 0.0242 | 1 |
Brugia malayi | AKH receptor | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.028 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.028 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.5529 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | = 1.24 ug ml-1 | Inhibitory effect on the proliferation of murine leukemia cells (L1210) | ChEMBL. | 1324318 |
ID50 (functional) | = 1.54 ug ml-1 | Inhibitory effect on the proliferation of human T-lymphoblast cells (Molt-4F) | ChEMBL. | 1324318 |
ID50 (functional) | = 3.53 ug ml-1 | Inhibitory effect on the proliferation of human T-lymphocyte (MT-4) | ChEMBL. | 1324318 |
MCC (functional) | = 40 ug ml-1 | Evaluation in HeLa cell cultures for cytotoxicity that is to cause microscopically detectable alteration of normal cell morphology | ChEMBL. | 1324318 |
MIC (functional) | = 3 ug ml-1 | Compound was evaluated for antiviral activity against respiratory syncitial virus (long) in HeLa cell cultures(Concentration required to reduce virus-induced cytopathogenicity by 50%) | ChEMBL. | 1324318 |
MIC (functional) | = 7 ug ml-1 | Evaluation for antiviral activity against vesicular stomatitis virus in HeLa cell cultures(Concentration required to reduce virus-induced cytopathogenicity by 50%) | ChEMBL. | 1324318 |
MIC (functional) | > 10 ug ml-1 | Evaluation for antiviral activity against Coxsackie virus B4 in HeLa cell cultures(Concentration required to reduce virus-induced cytopathogenicity by 50%) | ChEMBL. | 1324318 |
MIC (functional) | > 10 ug ml-1 | Evaluation for antiviral activity against polio virus-1 in HeLa cell cultures(Concentration required to reduce virus-induced cytopathogenicity by 50%) | ChEMBL. | 1324318 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.