Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0204 | 0 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1932 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0204 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0204 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1932 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0204 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0204 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0204 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0204 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0204 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0204 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0204 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0204 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0204 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.