Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | MET proto-oncogene, receptor tyrosine kinase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0062 | 0.1404 | 0.1089 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0062 | 0.1404 | 0.1089 |
Loa Loa (eye worm) | carboxylesterase | 0.0062 | 0.1404 | 0.1404 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0062 | 0.1404 | 0.1404 |
Echinococcus multilocularis | acetylcholinesterase | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1404 | 0.1404 |
Schistosoma mansoni | acetylcholinesterase | 0.0062 | 0.1404 | 0.1404 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0062 | 0.1404 | 0.1404 |
Loa Loa (eye worm) | carboxylesterase | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1404 | 0.1404 |
Brugia malayi | Carboxylesterase family protein | 0.0062 | 0.1404 | 0.1187 |
Echinococcus multilocularis | neuroligin | 0.0062 | 0.1404 | 0.1089 |
Onchocerca volvulus | 0.0062 | 0.1404 | 1 | |
Onchocerca volvulus | 0.0062 | 0.1404 | 1 | |
Brugia malayi | hypothetical protein | 0.0062 | 0.1404 | 0.1187 |
Brugia malayi | Carboxylesterase family protein | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0246 | 0.0246 |
Brugia malayi | plexin A | 0.0025 | 0.0354 | 0.0111 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0062 | 0.1404 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0062 | 0.1404 | 0.1187 |
Echinococcus multilocularis | acetylcholinesterase | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0062 | 0.1404 | 0.5 |
Onchocerca volvulus | 0.0062 | 0.1404 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0062 | 0.1404 | 0.1187 |
Brugia malayi | Carboxylesterase family protein | 0.0062 | 0.1404 | 0.1187 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1404 | 0.1404 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0062 | 0.1404 | 0.1404 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1404 | 0.1404 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1404 | 0.1404 |
Echinococcus granulosus | acetylcholinesterase | 0.0366 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0366 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0366 | 1 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0062 | 0.1404 | 0.1089 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0366 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0062 | 0.1404 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0062 | 0.1404 | 0.1404 |
Echinococcus granulosus | neuroligin | 0.0062 | 0.1404 | 0.1089 |
Loa Loa (eye worm) | plexin A | 0.0025 | 0.0354 | 0.0354 |
Onchocerca volvulus | 0.0062 | 0.1404 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0062 | 0.1404 | 0.1404 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0062 | 0.1404 | 0.5 |
Schistosoma mansoni | plexin | 0.0021 | 0.0246 | 0.0246 |
Onchocerca volvulus | 0.0062 | 0.1404 | 1 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0366 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0062 | 0.1404 | 0.1089 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0062 | 0.1404 | 0.1404 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0062 | 0.1404 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0062 | 0.1404 | 0.1404 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0062 | 0.1404 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0062 | 0.1404 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1404 | 0.1404 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1404 | 0.1404 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0062 | 0.1404 | 0.1089 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 25282552 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.