Detailed information for compound 930903

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2013.45 | Formula: C90H145N23O23S3
  • H donors: 21 H acceptors: 23 LogP: -5.66 Rotable bonds: 51
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N)CCC(=O)O)NC(=O)[C@@H]1CSSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)C)CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)Cc1ccccc1)CO)CC(=O)O)CCC2)CCCC
  • InChi: 1S/C90H145N23O23S3/c1-8-9-24-59-86(133)110-39-18-28-66(110)85(132)107-63(47-71(118)119)80(127)108-64(48-114)81(128)106-62(46-53-22-11-10-12-23-53)79(126)109-65(82(129)104-60(26-14-16-37-92)87(134)113-42-21-31-69(113)88(135)111-40-19-29-67(111)83(130)98-54(73(93)120)32-33-70(116)117)49-139-138-44-35-58(101-76(123)57(34-43-137-7)102-84(131)68-30-20-41-112(68)89(136)72(51(4)5)97-52(6)115)77(124)105-61(45-50(2)3)78(125)100-56(27-17-38-96-90(94)95)74(121)99-55(75(122)103-59)25-13-15-36-91/h10-12,22-23,50-51,54-69,72,114H,8-9,13-21,24-49,91-92H2,1-7H3,(H2,93,120)(H,97,115)(H,98,130)(H,99,121)(H,100,125)(H,101,123)(H,102,131)(H,103,122)(H,104,129)(H,105,124)(H,106,128)(H,107,132)(H,108,127)(H,109,126)(H,116,117)(H,118,119)(H4,94,95,96)/t54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,72-/m0/s1
  • InChiKey: JLFVYIWUQHPMTB-SFEKMHHOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.011 0.0286 0.0651
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.011 0.0286 0.0651
Echinococcus granulosus geminin 0.069 0.3993 0.9109
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0309 0.156 0.3558
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis Niemann Pick C1 protein 0.0309 0.156 0.156
Schistosoma mansoni peptide (allatostatin)-like receptor 0.011 0.0286 0.0651
Brugia malayi Melatonin receptor type 1A 0.011 0.0286 0.0651
Echinococcus multilocularis dro:myosuppressin receptor 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0752 0.4383 0.4383
Brugia malayi gonadotropin-releasing hormone receptor 2 0.011 0.0286 0.0651
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni hypothetical protein 0.069 0.3993 0.9109
Schistosoma mansoni neuropeptide f receptor 76f 0.011 0.0286 0.0651
Echinococcus granulosus 7tm_1 domain containing protein 0.011 0.0286 0.0651
Echinococcus multilocularis neuropeptide receptor A26 0.011 0.0286 0.0286
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.011 0.0286 0.0286
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.011 0.0286 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Echinococcus multilocularis G protein coupled receptor 139 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.0206 0.0899 0.2051
Echinococcus multilocularis neuropeptide Y receptor 0.011 0.0286 0.0286
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.0483 0.1102
Echinococcus granulosus serotonin receptor 0.011 0.0286 0.0651
Brugia malayi neuropeptide F receptor 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus granulosus sterol regulatory element binding protein 0.0309 0.156 0.3558
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.011 0.0286 0.0286
Schistosoma mansoni opsin-like receptor 0.011 0.0286 0.0651
Echinococcus multilocularis alpha 1A adrenergic receptor 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Echinococcus granulosus g-protein coupled receptor 0.011 0.0286 0.0651
Schistosoma mansoni neuropeptide receptor 0.011 0.0286 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Schistosoma mansoni neuropeptide receptor 0.011 0.0286 0.0651
Schistosoma mansoni myosin xvIII 0.011 0.0286 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Schistosoma mansoni amine GPCR 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0752 0.4383 1
Brugia malayi Serotonin receptor 0.011 0.0286 0.0651
Echinococcus multilocularis fmrfamide receptor 0.011 0.0286 0.0286
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.011 0.0286 0.0651
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0309 0.156 0.3558
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.011 0.0286 0.0651
Echinococcus granulosus neuropeptide receptor 0.011 0.0286 0.0651
Schistosoma mansoni amine GPCR 0.011 0.0286 0.0651
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.011 0.0286 0.0651
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0206 0.0899 0.2051
Onchocerca volvulus 0.011 0.0286 0.5
Schistosoma mansoni amine GPCR 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus granulosus g protein coupled receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis allatostatin A receptor 0.011 0.0286 0.0286
Brugia malayi follicle stimulating hormone receptor 0.011 0.0286 0.0651
Echinococcus granulosus Protein patched homolog 1 0.0309 0.156 0.3558
Onchocerca volvulus 0.011 0.0286 0.5
Onchocerca volvulus 0.011 0.0286 0.5
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0206 0.0899 0.2051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.011 0.0286 0.0286
Echinococcus granulosus neuropeptide s receptor 0.011 0.0286 0.0651
Brugia malayi Dopamine receptor protein 1 0.011 0.0286 0.0651
Echinococcus granulosus tachykinin peptides receptor 99D 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus alpha 1A adrenergic receptor 0.011 0.0286 0.0651
Schistosoma mansoni biogenic amine (5HT) receptor 0.011 0.0286 0.0651
Schistosoma mansoni biogenic amine receptor 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus granulosus neuropeptides capa receptor 0.011 0.0286 0.0651
Echinococcus multilocularis serotonin receptor 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0309 0.156 0.3558
Echinococcus granulosus somatostatin receptor 0.011 0.0286 0.0651
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus hypothetical protein 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0752 0.4383 0.5
Echinococcus granulosus fmrfamide receptor 0.011 0.0286 0.0651
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0752 0.4383 0.5
Echinococcus multilocularis protein patched 0.0309 0.156 0.156
Schistosoma mansoni hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus sex peptide receptor 0.011 0.0286 0.0651
Schistosoma mansoni neuropeptide receptor 0.011 0.0286 0.0651
Brugia malayi G-protein coupled receptor 0.011 0.0286 0.0651
Schistosoma mansoni hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis sex peptide receptor 0.011 0.0286 0.0286
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0353 0.1835 1
Echinococcus multilocularis fmrfamide receptor 0.011 0.0286 0.0286
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.011 0.0286 0.0286
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.011 0.0286 0.0651
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.011 0.0286 0.0651
Echinococcus multilocularis neuropeptide receptor 0.011 0.0286 0.0286
Brugia malayi sulfakinin receptor protein 0.011 0.0286 0.0651
Schistosoma mansoni neuropeptide F-like receptor 0.011 0.0286 0.0651
Echinococcus multilocularis protein dispatched 1 0.0309 0.156 0.156
Schistosoma mansoni amine GPCR 0.011 0.0286 0.0651
Schistosoma mansoni growth hormone secretagogue receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.011 0.0286 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0286 0.0651
Brugia malayi G protein-coupled receptor F59B2.13 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis g protein coupled receptor 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0286 0.0651
Schistosoma mansoni neuropeptide F-like receptor 0.011 0.0286 0.0651
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0752 0.4383 0.5
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Brugia malayi AKH receptor 0.011 0.0286 0.0651
Schistosoma mansoni biogenic amine (5HT) receptor 0.011 0.0286 0.0651
Echinococcus multilocularis orexin receptor type 2 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus g protein coupled receptor 0.011 0.0286 0.0651
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0752 0.4383 1
Brugia malayi GnHR receptor homolog 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.011 0.0286 0.0651
Echinococcus granulosus g protein coupled receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni patched 1 0.0309 0.156 0.3558
Echinococcus multilocularis serotonin receptor 0.011 0.0286 0.0286
Echinococcus granulosus neuropeptide FF receptor 2 0.011 0.0286 0.0651
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Brugia malayi Serotonin receptor 0.011 0.0286 0.0651
Schistosoma mansoni biogenic amine (dopamine) receptor 0.011 0.0286 0.0651
Echinococcus granulosus neuropeptide receptor 0.011 0.0286 0.0651
Echinococcus granulosus tm gpcr rhodopsin 0.011 0.0286 0.0651
Echinococcus multilocularis neuropeptide Y receptor 0.011 0.0286 0.0286
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.0141 0.0483 0.1102
Echinococcus granulosus neuropeptide Y receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis neuropeptide receptor 0.011 0.0286 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0286 0.0651
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis g protein coupled receptor 0.011 0.0286 0.0286
Onchocerca volvulus 0.011 0.0286 0.5
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis neuropeptides capa receptor 0.011 0.0286 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0286 0.0651
Brugia malayi putative neuropeptide receptor 0.011 0.0286 0.0651
Echinococcus granulosus Niemann Pick C1 protein 0.0309 0.156 0.3558
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus neuropeptide receptor A26 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Brugia malayi Dopamine receptor 0.011 0.0286 0.0651
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Schistosoma mansoni opsin-like receptor 0.011 0.0286 0.0651
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.011 0.0286 0.0651
Schistosoma mansoni adenoreceptor 0.011 0.0286 0.0651
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.011 0.0286 0.0651
Brugia malayi Calcitonin receptor-like protein seb-1 0.0206 0.0899 0.2051
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni hypothetical protein 0.011 0.0286 0.0651
Brugia malayi Tachykinin-like peptides receptor 99D 0.011 0.0286 0.0651
Schistosoma mansoni hypothetical protein 0.069 0.3993 0.9109
Brugia malayi neuropeptide F receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni biogenic amine receptor 0.011 0.0286 0.0651
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0353 0.1835 1
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0752 0.4383 1
Brugia malayi ORL1-like opioid receptor 0.011 0.0286 0.0651
Echinococcus multilocularis G-protein coupled receptor, putative 0.011 0.0286 0.0286
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni biogenic amine (dopamine) receptor 0.011 0.0286 0.0651
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0286 0.0651
Schistosoma mansoni amine GPCR 0.011 0.0286 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0353 0.1835 1
Loa Loa (eye worm) TYRA-2 protein 0.011 0.0286 0.0651
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0286 0.0651
Echinococcus multilocularis neuropeptides capa receptor 0.011 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) follicle stimulating hormone receptor 0.011 0.0286 0.0651
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.011 0.0286 0.0286
Echinococcus granulosus peptide allatostatin:somatostatin 0.011 0.0286 0.0651
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Schistosoma mansoni biogenic amine (dopamine) receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) G-protein coupled receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Brugia malayi RE15519p 0.011 0.0286 0.0651
Echinococcus multilocularis neuropeptide s receptor 0.011 0.0286 0.0286
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.011 0.0286 0.0651
Brugia malayi Serotonin/octopamine receptor family protein 7 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus allatostatin A receptor 0.011 0.0286 0.0651
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.011 0.0286 0.0286
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.011 0.0286 0.0651
Schistosoma mansoni neuropeptide receptor 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus granulosus dro:myosuppressin receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus granulosus biogenic amine 5HT receptor 0.011 0.0286 0.0651
Schistosoma mansoni hypothetical protein 0.0141 0.0483 0.1102
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Onchocerca volvulus Neuropeptide F receptor homolog 0.011 0.0286 0.5
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.0752 0.4383 1
Brugia malayi larval opioid receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) G-protein coupled receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Brugia malayi G-protein coupled receptor 0.011 0.0286 0.0651
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.011 0.0286 0.0286
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus tm gpcr rhodopsin 0.011 0.0286 0.0651
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0353 0.1835 0.5
Echinococcus granulosus orexin receptor type 2 0.011 0.0286 0.0651
Echinococcus multilocularis sterol regulatory element binding protein 0.0309 0.156 0.156
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus biogenic amine 5HT receptor 0.011 0.0286 0.0651
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.011 0.0286 0.0286
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Echinococcus granulosus neuropeptides capa receptor 0.011 0.0286 0.0651
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.011 0.0286 0.0286
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis geminin 0.069 0.3993 0.3993
Schistosoma mansoni histamine h1 receptor 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Brugia malayi CHE-14 protein 0.0309 0.156 0.3558
Onchocerca volvulus 0.011 0.0286 0.5
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus granulosus G protein coupled receptor 139 0.011 0.0286 0.0651
Echinococcus granulosus neuropeptide Y receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Echinococcus multilocularis tachykinin peptides receptor 99D 0.011 0.0286 0.0286
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.011 0.0286 0.0651
Brugia malayi hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0752 0.4383 0.5
Schistosoma mansoni opsin-like receptor 0.011 0.0286 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.011 0.0286 0.0651
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.011 0.0286 0.0651
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0752 0.4383 0.5
Echinococcus multilocularis neuropeptide FF receptor 2 0.011 0.0286 0.0286
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Echinococcus multilocularis biogenic amine (5HT) receptor 0.011 0.0286 0.0286
Schistosoma mansoni alpha-1 adrenergic receptor 0.011 0.0286 0.0651
Echinococcus granulosus 7TM GPCR rhodopsin 0.011 0.0286 0.0651
Echinococcus multilocularis g protein coupled receptor 0.011 0.0286 0.0286
Schistosoma mansoni biogenic amine receptor 0.011 0.0286 0.0651
Schistosoma mansoni hypothetical protein 0.011 0.0286 0.0651
Loa Loa (eye worm) neuropeptide F receptor 0.011 0.0286 0.0651
Brugia malayi Dopamine receptor protein 2 0.011 0.0286 0.0651
Echinococcus multilocularis rhodopsin orphan GPCR 0.011 0.0286 0.0286
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus multilocularis g-protein coupled receptor 0.011 0.0286 0.0286
Brugia malayi G protein-coupled receptor 0.011 0.0286 0.0651
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.011 0.0286 0.0651
Loa Loa (eye worm) melatonin receptor type 1A 0.011 0.0286 0.0651
Onchocerca volvulus 0.011 0.0286 0.5
Echinococcus granulosus thyrotropin releasing hormone receptor 0.011 0.0286 0.0651
Echinococcus multilocularis somatostatin receptor 0.011 0.0286 0.0286
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.011 0.0286 0.0651
Loa Loa (eye worm) neuropeptide F receptor 0.011 0.0286 0.0651
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.011 0.0286 0.0651
Brugia malayi putative neuropeptide receptor NPR1 0.011 0.0286 0.0651
Loa Loa (eye worm) hypothetical protein 0.011 0.0286 0.0651

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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