Detailed information for compound 931105

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 234.278 | Formula: C10H10N4OS
  • H donors: 1 H acceptors: 2 LogP: 1.13 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/C(=N\N=C/1\SCC(=O)N1)/c1ccncc1
  • InChi: 1S/C10H10N4OS/c1-7(8-2-4-11-5-3-8)13-14-10-12-9(15)6-16-10/h2-5H,6H2,1H3,(H,12,14,15)/b13-7+
  • InChiKey: PXQSRKXXQZJTGD-NTUHNPAUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Trypanosoma cruzi DNA repair protein, putative 0.0018 0.0061 0.4134
Echinococcus granulosus beta-adrenergic receptor kinase 0.0011 0.0023 0.0047
Echinococcus multilocularis axis inhibition protein axin 0.001 0.0021 0.0044
Echinococcus granulosus acetylcholinesterase 0.0877 0.4877 1
Echinococcus granulosus axis inhibition protein axin 0.001 0.0021 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0524 0.594
Schistosoma mansoni microsomal glutathione s-transferase 0.0198 0.1072 0.2197
Toxoplasma gondii MAPEG family protein 0.0198 0.1072 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0021 0.0013
Echinococcus granulosus cpg binding protein 0.0018 0.0063 0.0129
Schistosoma mansoni hypothetical protein 0.0017 0.0057 0.0118
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0818 0.941
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0002
Echinococcus multilocularis regulator of G protein signaling 3 0.001 0.0021 0.0044
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.001 0.002 0.0041
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.001 0.0021 0.0044
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0028 0.0119 1
Echinococcus multilocularis expressed protein 0.0204 0.1107 0.2269
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0021 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0524 0.594
Echinococcus granulosus regulator of G protein signaling 3 0.001 0.0021 0.0044
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0028 0.0119 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.001 0.0021 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0106 0.0554 0.6297
Brugia malayi hypothetical protein 0.0015 0.0046 0.0061
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0057 0.0118
Entamoeba histolytica hypothetical protein 0.001 0.0021 0.0014
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0877 0.4877 1
Echinococcus granulosus neuroligin 0.0148 0.0793 0.1626
Schistosoma mansoni neuroligin 3 (S09 family) 0.0148 0.0793 0.1626
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0524 0.594
Echinococcus multilocularis axis inhibition protein axin 0.001 0.0021 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0021 0.0013
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0028 0.0119 1
Loa Loa (eye worm) carboxylesterase 0.0148 0.0793 0.1591
Schistosoma mansoni Replicative DNA helicase 0.0204 0.1107 0.227
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.0046 0.2621
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0119 0.1163
Brugia malayi PXA domain containing protein 0.001 0.0021 0.001
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0028 0.0119 1
Echinococcus multilocularis acetylcholinesterase 0.0877 0.4877 1
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0167 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0818 0.941
Brugia malayi Carboxylesterase family protein 0.0148 0.0793 0.1598
Schistosoma mansoni z-protein (S1r protein) 0.001 0.0021 0.0044
Brugia malayi hypothetical protein 0.0148 0.0793 0.1598
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0262 0.0498
Schistosoma mansoni regulator of G protein signaling 0.001 0.0021 0.0044
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1644 0.9175 0.9173
Plasmodium vivax ataxin-2 like protein, putative 0.0015 0.0046 1
Echinococcus multilocularis regulator of G protein signaling 3 0.001 0.0021 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0119 0.1163
Echinococcus multilocularis Regulator of G protein signaling 20 0.001 0.0021 0.0044
Echinococcus granulosus BC026374 protein S09 family 0.0148 0.0793 0.1626
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0021 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0119 0.1163
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0075 0.0385 0.336
Treponema pallidum replicative DNA helicase (dnaB) 0.0204 0.1107 1
Brugia malayi Carboxylesterase family protein 0.0148 0.0793 0.1598
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Mycobacterium leprae Conserved hypothetical protein 0.0602 0.3337 1
Loa Loa (eye worm) carboxylesterase 0.0877 0.4877 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0021 0.0013
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0021 0.0044
Brugia malayi MAP kinase sur-1 0.0028 0.0119 0.021
Echinococcus multilocularis neuroligin 0.0148 0.0793 0.1626
Brugia malayi CXXC zinc finger family protein 0.0017 0.0058 0.0085
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0148 0.0793 0.0774
Echinococcus granulosus carboxylesterase 5A 0.0877 0.4877 1
Onchocerca volvulus 0.0148 0.0793 1
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0818 0.941
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.001 0.0021 0.0013
Brugia malayi Regulator of G protein signaling domain containing protein 0.001 0.0021 0.001
Schistosoma mansoni hypothetical protein 0.0037 0.0167 0.0343
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Schistosoma mansoni regulator of G protein signaling 0.001 0.0021 0.0044
Loa Loa (eye worm) hypothetical protein 0.0053 0.0262 0.0498
Loa Loa (eye worm) hypothetical protein 0.0877 0.4877 1
Leishmania major hypothetical protein, conserved 0.0015 0.0046 0.2621
Entamoeba histolytica hypothetical protein 0.001 0.0021 0.0014
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.001 0.002 0.0041
Treponema pallidum recombinase A 0.0057 0.0282 0.241
Echinococcus granulosus GPCR family 2 0.0017 0.0057 0.0118
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.001 0.0021 0.0002
Toxoplasma gondii LsmAD domain-containing protein 0.0015 0.0046 0.0246
Echinococcus multilocularis tumor protein p63 0.0179 0.0963 0.1975
Schistosoma mansoni gliotactin 0.0148 0.0793 0.1626
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0057 0.0118
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0002
Schistosoma mansoni ap endonuclease 0.001 0.002 0.0041
Schistosoma mansoni ap endonuclease 0.001 0.002 0.0041
Loa Loa (eye worm) hypothetical protein 0.0015 0.0046 0.0053
Schistosoma mansoni cpg binding protein 0.0018 0.0063 0.0129
Echinococcus granulosus mitogen activated protein kinase 0.0028 0.0119 0.0243
Schistosoma mansoni cpg binding protein 0.0017 0.0058 0.0118
Loa Loa (eye worm) hypothetical protein 0.0148 0.0793 0.1591
Trichomonas vaginalis glutaminase, putative 0.0162 0.0868 1
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0148 0.0793 0.1626
Schistosoma mansoni regulator of G protein signaling 0.001 0.0021 0.0044
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0075 0.0385 0.0366
Loa Loa (eye worm) hypothetical protein 0.0148 0.0793 0.1591
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0262 0.0506
Echinococcus multilocularis para nitrobenzyl esterase 0.0148 0.0793 0.1626
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0018 0.0061 0.4134
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0028 0.0119 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0148 0.0793 0.1626
Loa Loa (eye worm) carboxylesterase 0.0148 0.0793 0.1591
Trypanosoma brucei PAB1-binding protein , putative 0.0015 0.0046 0.2621
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0057 0.0077
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0204 0.1107 0.27
Entamoeba histolytica hypothetical protein 0.001 0.0021 0.0014
Schistosoma mansoni regulator of G protein signaling 0.001 0.0021 0.0044
Loa Loa (eye worm) PXA domain-containing protein 0.001 0.0021 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0002
Brugia malayi hypothetical protein 0.001 0.0021 0.001
Brugia malayi Carboxylesterase family protein 0.0877 0.4877 1
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0204 0.1107 1
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0021 0.0044
Echinococcus granulosus para nitrobenzyl esterase 0.0148 0.0793 0.1626
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0011 0.0023 0.0005
Schistosoma mansoni acetylcholinesterase 0.0148 0.0793 0.1626
Onchocerca volvulus 0.0148 0.0793 1
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0057 0.0282 0.241
Loa Loa (eye worm) glutaminase 2 0.0162 0.0868 0.1745
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0028 0.0119 0.0203
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0011 0.0023 0.0013
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0057 0.0084
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0148 0.0793 0.1626
Giardia lamblia Fructose-bisphosphate aldolase 0.0155 0.0828 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.001 0.0021 0.0044
Loa Loa (eye worm) glutaminase 0.0162 0.0868 0.1745
Loa Loa (eye worm) CXXC zinc finger family protein 0.0017 0.0058 0.0077
Onchocerca volvulus 0.0026 0.0109 0.0699
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0262 0.0506
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0479 0.2648 0.5429
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.001 0.0021 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0524 0.594
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0204 0.1107 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0153 0.0818 0.1642
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0046 1
Schistosoma mansoni axis inhibition protein axin 0.001 0.0021 0.0044
Trichomonas vaginalis spcc417.12 protein, putative 0.0148 0.0793 0.9117
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0057 0.0118
Trypanosoma brucei protein kinase, putative 0.0028 0.0119 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0148 0.0793 0.9117
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0198 0.1072 0.2197
Onchocerca volvulus 0.0148 0.0793 1
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0524 0.594
Schistosoma mansoni hypothetical protein 0.0017 0.0057 0.0118
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.001 0.0021 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0036 0.0164 0.0337
Echinococcus multilocularis BC026374 protein (S09 family) 0.0148 0.0793 0.1626
Echinococcus granulosus microsomal glutathione S transferase 3 0.0198 0.1072 0.2197
Echinococcus granulosus tumor protein p63 0.0179 0.0963 0.1975
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0818 0.941
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0028 0.0119 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Brugia malayi Carboxylesterase family protein 0.0148 0.0793 0.1598
Echinococcus multilocularis acetylcholinesterase 0.0877 0.4877 1
Schistosoma mansoni regulator of G protein signaling 0.001 0.0021 0.0044
Brugia malayi regulator of G-protein signaling egl-10 0.001 0.0021 0.001
Schistosoma mansoni BC026374 protein (S09 family) 0.0148 0.0793 0.1626
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0057 0.0118
Brugia malayi Carboxylesterase family protein 0.0877 0.4877 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0002
Brugia malayi exodeoxyribonuclease III family protein 0.001 0.002 0.0008
Echinococcus multilocularis regulator of G protein signaling 0.001 0.0021 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0119 0.0243
Loa Loa (eye worm) hypothetical protein 0.0037 0.0167 0.0303
Brugia malayi PXA domain containing protein 0.001 0.0021 0.001
Schistosoma mansoni hypothetical protein 0.0017 0.0057 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0155 0.0828 1
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0023 0.0047
Brugia malayi hypothetical protein 0.001 0.0021 0.001
Echinococcus granulosus axis inhibition protein axin 0.001 0.0021 0.0044
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0148 0.0793 0.0774
Echinococcus granulosus Regulator of G protein signaling 20 0.001 0.0021 0.0044
Loa Loa (eye worm) twinkle helicase 0.0058 0.029 0.0555
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Brugia malayi Carboxylesterase family protein 0.0148 0.0793 0.1598
Echinococcus multilocularis mitogen activated protein kinase 0.0028 0.0119 0.0243
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0075 0.0385 0.0338
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0028 0.0119 0.0937
Echinococcus multilocularis beta adrenergic receptor kinase 0.0011 0.0023 0.0047
Echinococcus granulosus expressed protein 0.0204 0.1107 0.2269
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0524 0.594
Onchocerca volvulus 0.0148 0.0793 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0153 0.0818 0.1649
Trypanosoma cruzi PAB1-binding protein , putative 0.0015 0.0046 0.2621
Trichomonas vaginalis glucosylceramidase, putative 0.0106 0.0554 0.6297
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0028 0.0119 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0021 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Toxoplasma gondii histone lysine methyltransferase SET1 0.0032 0.0143 0.1165
Mycobacterium ulcerans carboxylesterase, LipT 0.0148 0.0793 0.711
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0155 0.0828 1
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0198 0.1072 0.2197
Onchocerca volvulus Glucosylceramidase homolog 0.01 0.0524 0.6338
Trichomonas vaginalis CMGC family protein kinase 0.0028 0.0119 0.1163
Schistosoma mansoni cpg binding protein 0.0018 0.0063 0.0129
Loa Loa (eye worm) hypothetical protein 0.0148 0.0793 0.1591
Mycobacterium tuberculosis Carboxylesterase LipT 0.0148 0.0793 0.0774
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0148 0.0793 0.1626
Loa Loa (eye worm) acetylcholinesterase 1 0.0877 0.4877 1
Loa Loa (eye worm) RGS-3 protein 0.001 0.0021 0.0002
Schistosoma mansoni cellular tumor antigen P53 0.0026 0.0109 0.0224
Mycobacterium ulcerans recombinase A 0.0057 0.0282 0.241
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0818 0.941
Schistosoma mansoni axis inhibition protein axin 0.001 0.0021 0.0044
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0002
Echinococcus multilocularis mitogen activated protein kinase 3 0.0028 0.0119 0.0243
Loa Loa (eye worm) hypothetical protein 0.0148 0.0793 0.1591
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0023 0.0047
Brugia malayi glutaminase DH11.1 0.0162 0.0868 0.1751
Chlamydia trachomatis replicative DNA helicase 0.0204 0.1107 1
Giardia lamblia Kinase, CMGC MAPK 0.0028 0.0119 0.122
Loa Loa (eye worm) hypothetical protein 0.0148 0.0793 0.1591
Plasmodium falciparum ataxin-2 like protein, putative 0.0015 0.0046 1
Schistosoma mansoni glutaminase 0.0162 0.0868 0.1779
Loa Loa (eye worm) hypothetical protein 0.0148 0.0793 0.1591
Loa Loa (eye worm) hypothetical protein 0.0148 0.0793 0.1591
Echinococcus multilocularis GPCR, family 2 0.0017 0.0057 0.0118
Echinococcus multilocularis carboxylesterase 5A 0.0877 0.4877 1
Trypanosoma cruzi DNA repair protein, putative 0.0018 0.0061 0.4134
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0057 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0021 0.0013
Echinococcus granulosus regulator of G protein signaling 3 0.001 0.0021 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0023 0.0047
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0011 0.0023 0.0005
Loa Loa (eye worm) hypothetical protein 0.0877 0.4877 1
Treponema pallidum fructose-bisphosphate aldolase 0.0155 0.0828 0.7434
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0155 0.0828 0.9533
Brugia malayi A-kinase anchor protein 10, precursor 0.001 0.0021 0.001
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.001 0.0021 0.0044
Onchocerca volvulus 0.0148 0.0793 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0057 0.0077
Mycobacterium ulcerans glutaminase 0.0162 0.0868 0.7798
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0021 0.0044
Echinococcus granulosus acetylcholinesterase 0.0877 0.4877 1
Echinococcus multilocularis cpg binding protein 0.0018 0.0063 0.0129
Echinococcus granulosus mitogen activated protein kinase 3 0.0028 0.0119 0.0243
Trichomonas vaginalis glucosylceramidase, putative 0.01 0.0524 0.594
Schistosoma mansoni hypothetical protein 0.0017 0.0057 0.0118
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0148 0.0793 0.1626
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.0818 0.941
Brugia malayi regulator of G-protein signaling rgs-7 0.001 0.0021 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0109 0.0183

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 53 uM Antiparasitic activity against Toxoplasma gondii infected in human foreskin fibroblasts assessed as tachyzoite growth inhibition after 5 days by colorimetric assay ChEMBL. 25140751
TD50 (ADMET) >= 320 uM Cytotoxicity against human foreskin fibroblasts after 5 days by colorimetric assay ChEMBL. 25140751

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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