Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0483 | 0.5924 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0839 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0099 | 0.0839 | 0.1417 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | protein phosphatase 1b | 0.0081 | 0.0612 | 0.1033 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | protein phosphatase 2C | 0.0081 | 0.0612 | 0.7287 |
Brugia malayi | Protein phosphatase 2C containing protein | 0.0081 | 0.0612 | 0.1033 |
Schistosoma mansoni | survival motor neuron protein | 0.0099 | 0.0839 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0483 | 0.5924 | 1 |
Onchocerca volvulus | 0.0099 | 0.0839 | 1 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.2497 | 0.2497 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0483 | 0.5924 | 1 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.0791 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0483 | 0.5924 | 1 |
Schistosoma mansoni | protein phosphatase 2C | 0.0071 | 0.0476 | 0.5666 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | protein phosphatase 2C containing protein | 0.0081 | 0.0612 | 0.1033 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0 | 0.5 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Mycobacterium ulcerans | proteasome PrcA | 0.0791 | 1 | 1 |
Echinococcus granulosus | protein phosphatase 1b | 0.0081 | 0.0612 | 0.1033 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | protein phosphatase 2C | 0.0071 | 0.0476 | 0.5666 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | protein phosphatase 1b | 0.0071 | 0.0476 | 0.0803 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | protein phosphatase 1b | 0.0071 | 0.0476 | 0.0803 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.