Detailed information for compound 936477

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 512.603 | Formula: C29H32N6O3
  • H donors: 3 H acceptors: 3 LogP: 3.91 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(Nc1ccc(cc1)Nc1ncnc2c1ccc(c2)OCCCN1CCOCC1)NCc1ccccc1
  • InChi: 1S/C29H32N6O3/c36-29(30-20-22-5-2-1-3-6-22)34-24-9-7-23(8-10-24)33-28-26-12-11-25(19-27(26)31-21-32-28)38-16-4-13-35-14-17-37-18-15-35/h1-3,5-12,19,21H,4,13-18,20H2,(H2,30,34,36)(H,31,32,33)
  • InChiKey: ZORWXMUNOJMUBY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aurora kinase A Starlite/ChEMBL References
Homo sapiens aurora kinase B Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania infantum protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine protein kinase 6 Get druggable targets OG5_127024 All targets in OG5_127024
Cryptosporidium hominis protein kinase (EC 2.7.1.-) p46XlEg22 Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium knowlesi serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis serine:threonine protein kinase 12 B Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica serine/threonine- protein kinase 6 , putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Cryptosporidium parvum protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium berghei serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma japonicum Serine/threonine-protein kinase 12, putative Get druggable targets OG5_127024 All targets in OG5_127024
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Get druggable targets OG5_127024 All targets in OG5_127024
Toxoplasma gondii aurora kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium vivax serine/threonine protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania major protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine-protein kinase 6 Get druggable targets OG5_127024 All targets in OG5_127024
Neospora caninum hypothetical protein Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Giardia lamblia Aurora kinase Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis aurora kinase A Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine kinase 12 Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma congolense aurora B kinase Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma japonicum ko:K08850 aurora kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma cruzi aurora B kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica serine/threonine- protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus granulosus serine:threonine protein kinase 12 B Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania donovani Aurora I-related kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium yoelii putative protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica serine/threonine protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania mexicana protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma brucei aurora B kinase Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma mansoni protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase , putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus granulosus aurora kinase A Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 aurora kinase B 303 aa 299 aa 22.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0481 0.1323 0.1151
Brugia malayi RhoGEF domain containing protein 0.0338 0.085 0.0793
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0219 0.1346
Echinococcus multilocularis RNA directed DNA polymerase 0.2205 0.7049 0.699
Loa Loa (eye worm) AUR protein kinase 0.0148 0.0219 0.0268
Schistosoma mansoni atypical protein kinase C 0.0819 0.2445 0.2295
Trichomonas vaginalis cyclins, putative 0.0141 0.0195 0.1159
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Entamoeba histolytica protein kinase domain containing protein 0.0148 0.0219 0.1633
Echinococcus granulosus raf serine:threonine protein kinase 0.0338 0.085 0.0668
Entamoeba histolytica cyclin, putative 0.0141 0.0195 0.1453
Brugia malayi C1-like domain containing protein 0.0351 0.0892 0.0845
Brugia malayi diacylglycerol kinase 0.0338 0.085 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.0481 0.1323 0.1151
Brugia malayi Variant SH3 domain containing protein 0.0338 0.085 0.0793
Brugia malayi p70 ribosomal S6 kinase beta 0.0481 0.1323 0.1367
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0148 0.0219 0.5
Echinococcus granulosus N chimaerin 0.0338 0.085 0.0668
Echinococcus multilocularis serine:threonine protein kinase N2 0.0481 0.1323 0.1151
Schistosoma mansoni serine/threonine kinase 0.0481 0.1323 0.1151
Loa Loa (eye worm) AUR protein kinase 0.0148 0.0219 0.0268
Echinococcus multilocularis serine:threonine protein kinase 38 0.0481 0.1323 0.1151
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0338 0.085 0.0668
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.0892 0.0711
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Echinococcus multilocularis serine threonine protein kinase 0.2756 0.8878 0.8855
Toxoplasma gondii AGC kinase 0.0481 0.1323 1
Echinococcus granulosus NDR protein kinase 0.0481 0.1323 0.1151
Echinococcus multilocularis aurora kinase A 0.0148 0.0219 0.0024
Leishmania major protein kinase, putative 0.0148 0.0219 1
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Echinococcus granulosus protein kinase C gamma type 0.2756 0.8878 0.8855
Schistosoma mansoni serine/threonine protein kinase 0.0481 0.1323 0.1151
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Trichomonas vaginalis cyclin B, putative 0.0141 0.0195 0.1159
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Loa Loa (eye worm) hypothetical protein 0.0141 0.0195 0.0239
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Entamoeba histolytica protein kinase, putative 0.0148 0.0219 0.1633
Echinococcus multilocularis serine:threonine protein kinase N2 0.0481 0.1323 0.1151
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0889 0.2679 0.3278
Trypanosoma brucei rac serine-threonine kinase, putative 0.0481 0.1323 1
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0351 0.0892 0.0711
Schistosoma mansoni protein kinase 0.0148 0.0219 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Entamoeba histolytica diacylglycerol kinase, putative 0.0338 0.085 0.6412
Trichomonas vaginalis cyclin B, putative 0.0141 0.0195 0.1159
Plasmodium falciparum serine/threonine protein kinase, putative 0.0148 0.0219 0.5
Entamoeba histolytica protein kinase, putative 0.0148 0.0219 0.1633
Loa Loa (eye worm) AGC/NDR protein kinase 0.0481 0.1323 0.1619
Echinococcus granulosus protein kinase c eta type 0.0338 0.085 0.0668
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0595 0.1703 0.2084
Echinococcus multilocularis myotubularin protein 13 0.0338 0.085 0.0668
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0148 0.0219 0.1633
Schistosoma mansoni serine/threonine protein kinase 0.3094 1 1
Trichomonas vaginalis cyclins, putative 0.0141 0.0195 0.1159
Brugia malayi Protein kinase c protein 2 0.2626 0.8447 1
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Brugia malayi Pleckstrin Homology Domain 0.0338 0.085 0.0793
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0219 0.1346
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0481 0.1323 0.1151
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Brugia malayi Protein kinase domain containing protein 0.0481 0.1323 0.1367
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0338 0.085 0.104
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Echinococcus granulosus protein kinase c epsilon type 0.0889 0.2679 0.2533
Trichomonas vaginalis cyclin B, putative 0.0141 0.0195 0.1159
Echinococcus multilocularis protein kinase c eta type 0.0338 0.085 0.0668
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Giardia lamblia Aurora kinase 0.0148 0.0219 1
Loa Loa (eye worm) raf kinase 0.0338 0.085 0.104
Loa Loa (eye worm) AGC/PKN protein kinase 0.0481 0.1323 0.1619
Echinococcus multilocularis protein kinase c epsilon type 0.0889 0.2679 0.2533
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0351 0.0892 0.1092
Loa Loa (eye worm) hypothetical protein 0.0481 0.1323 0.1619
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Brugia malayi Hr1 repeat family protein 0.0481 0.1323 0.1367
Schistosoma mansoni rac gtpase activating protein 0.0338 0.085 0.0668
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0545 0.1537 0.1369
Schistosoma mansoni serine/threonine protein kinase 0.3094 1 1
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0219 0.1346
Echinococcus granulosus serine:threonine protein kinase N2 0.0481 0.1323 0.1151
Echinococcus granulosus RNA directed DNA polymerase 0.2205 0.7049 0.699
Echinococcus granulosus protein kinase c iota type 0.0819 0.2445 0.2295
Onchocerca volvulus 0.0338 0.085 0.7374
Brugia malayi serine/threonine-protein kinase 6 0.0148 0.0219 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0889 0.2679 0.2533
Brugia malayi serine/threonine kinase 12 0.0148 0.0219 0.0029
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.2288 0.7325 0.8964
Trypanosoma brucei aurora B kinase 0.0148 0.0219 0.0211
Schistosoma mansoni unc-13 (munc13) 0.0408 0.1083 0.0905
Schistosoma mansoni serine/threonine protein kinase 0.0481 0.1323 0.1151
Echinococcus multilocularis raf serine:threonine protein kinase 0.0338 0.085 0.0668
Schistosoma mansoni unc-13 (munc13) 0.0408 0.1083 0.0905
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0351 0.0892 0.0711
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0545 0.1537 0.1369
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Echinococcus granulosus Rac GTPase activating protein 1 0.0338 0.085 0.0668
Entamoeba histolytica hypothetical protein 0.0338 0.085 0.6412
Brugia malayi protein kinase C3,putative 0.0351 0.0892 0.0845
Echinococcus multilocularis protein kinase c iota type 0.0819 0.2445 0.2295
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0351 0.0892 0.1092
Entamoeba histolytica protein kinase, putative 0.0481 0.1323 1
Entamoeba histolytica protein kinase , putative 0.0148 0.0219 0.1633
Echinococcus multilocularis Diacylglycerol kinase theta 0.0338 0.085 0.0668
Echinococcus granulosus unc 13 munc13 0.0408 0.1083 0.0905
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0338 0.085 0.0668
Loa Loa (eye worm) hypothetical protein 0.0141 0.0195 0.0239
Trichomonas vaginalis cyclin B, putative 0.0141 0.0195 0.1159
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0219 0.0024
Trichomonas vaginalis cyclin A, putative 0.0141 0.0195 0.1159
Trichomonas vaginalis cyclins, putative 0.0141 0.0195 0.1159
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Loa Loa (eye worm) hypothetical protein 0.2543 0.8171 1
Brugia malayi Protein kinase domain containing protein 0.0351 0.0892 0.0845
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0408 0.1083 0.0905
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Echinococcus multilocularis N chimaerin 0.0338 0.085 0.0668
Echinococcus multilocularis Rac GTPase activating protein 1 0.0338 0.085 0.0668
Schistosoma mansoni protein kinase C mu 0.0351 0.0892 0.0711
Brugia malayi RhoGAP domain containing protein 0.0338 0.085 0.0793
Echinococcus granulosus aurora kinase A 0.0148 0.0219 0.0024
Echinococcus granulosus myotubularin protein 13 0.0338 0.085 0.0668
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0481 0.1323 0.1151
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0351 0.0892 0.0845
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0481 0.1323 0.1619
Schistosoma mansoni protein kinase C 0.0408 0.1083 0.0905
Entamoeba histolytica protein kinase, putative 0.0481 0.1323 1
Loa Loa (eye worm) hypothetical protein 0.2205 0.7049 0.8627
Echinococcus multilocularis Protein kinase C, brain isozyme 0.3094 1 1
Onchocerca volvulus 0.0338 0.085 0.7374
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0148 0.0219 0.1633
Loa Loa (eye worm) AUR protein kinase 0.0148 0.0219 0.0268
Loa Loa (eye worm) AGC/AKT protein kinase 0.0481 0.1323 0.1619
Entamoeba histolytica diacylglycerol kinase, putative 0.0338 0.085 0.6412
Onchocerca volvulus 0.0408 0.1083 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0338 0.085 0.104
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0338 0.085 0.0668
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0481 0.1323 0.1619
Echinococcus multilocularis unc 13 (munc13) 0.0408 0.1083 0.0905
Schistosoma mansoni serine/threonine protein kinase 0.0481 0.1323 0.1151
Brugia malayi protein kinase C II. 0.0889 0.2679 0.301
Trichomonas vaginalis AGC family protein kinase 0.0481 0.1323 1
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.0892 0.0711
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0408 0.1083 0.0905
Toxoplasma gondii diacylglycerol kinase, putative 0.0338 0.085 0.5712
Brugia malayi diacylglycerol kinase 0.0338 0.085 0.0793
Brugia malayi Protein kinase domain containing protein 0.0481 0.1323 0.1367
Schistosoma mansoni diacylglycerol kinase theta 0.0338 0.085 0.0668
Loa Loa (eye worm) hypothetical protein 0.0338 0.085 0.104
Entamoeba histolytica protein kinase, putative 0.0481 0.1323 1
Trypanosoma cruzi aurora B kinase, putative 0.0148 0.0219 1
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0338 0.085 0.0668
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0468 0.128 0.9664
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0219 0.1346
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0481 0.1323 0.1151
Schistosoma mansoni protein kinase C mu 0.0338 0.085 0.0668
Entamoeba histolytica protein kinase, putative 0.0481 0.1323 1
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0148 0.0219 0.1633
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0481 0.1323 0.1151
Loa Loa (eye worm) hypothetical protein 0.0408 0.1083 0.1325
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0148 0.0219 0.0024
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0148 0.0219 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0338 0.085 0.0668
Brugia malayi serine/threonine protein kinase 6 0.0148 0.0219 0.0029
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.2205 0.7049 0.699
Loa Loa (eye worm) RasGEF domain-containing protein 0.0338 0.085 0.104
Echinococcus granulosus Diacylglycerol kinase theta 0.0338 0.085 0.0668
Brugia malayi Protein kinase domain containing protein 0.0481 0.1323 0.1367
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0481 0.1323 0.1619
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0338 0.085 0.104
Brugia malayi RhoGAP domain containing protein 0.0338 0.085 0.0793
Schistosoma mansoni hypothetical protein 0.0338 0.085 0.0668
Brugia malayi serine/threonine-protein kinase PAK 7 0.0595 0.1703 0.1827
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0481 0.1323 0.1151
Schistosoma mansoni vav2 0.0338 0.085 0.0668
Brugia malayi Ras association domain family 1 isoform A 0.0338 0.085 0.0793
Schistosoma mansoni diacylglycerol kinase theta 0.0338 0.085 0.0668
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0481 0.1323 0.1619
Trichomonas vaginalis cyclins, putative 0.0141 0.0195 0.1159

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 212 nM Inhibition of Aurora-A (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assay ChEMBL. 25270403
IC50 (binding) = 367 nM Inhibition of Aurora-B (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assay ChEMBL. 25270403
IC50 (functional) = 18.3 uM Antiproliferative activity against human A549 cells after 72 hrs by MTT-based WST8 reagent assay ChEMBL. 25270403
IC50 (functional) > 100 uM Antiproliferative activity against human K562 cells after 72 hrs by MTT-based WST8 reagent assay ChEMBL. 25270403
Inhibition (binding) = 45.3 % Inhibition of EGFR (unknown origin) at 10 uM by HTScan assay ChEMBL. 25270403

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 25270403

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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