Detailed information for compound 936931

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 435.229 | Formula: C18H16INO4
  • H donors: 0 H acceptors: 2 LogP: 3.22 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC1=CC(=O)c2c(C1=O)c(COc1cccc(c1)[125I])c(n2C)C
  • InChi: 1S/C18H16INO4/c1-10-13(9-24-12-6-4-5-11(19)7-12)16-17(20(10)2)14(21)8-15(23-3)18(16)22/h4-8H,9H2,1-3H3/i19-2
  • InChiKey: RQOSGKPKPSSKBG-GBVACIEGSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Leishmania major cathepsin L-like protease 0.0012 0.0003 0.0011
Plasmodium falciparum thioredoxin reductase 0.0013 0.0004 0.0014
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0014
Onchocerca volvulus 0.0013 0.0004 0.0045
Loa Loa (eye worm) hypothetical protein 0.005 0.0063 0.0641
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0004 0.0014
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.001 0.0132
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0019
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0016 0.0009 0.0007
Brugia malayi Patched related family protein 10 0.0013 0.0004 0.0032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0414 1
Plasmodium vivax kinesin-5 0.0166 0.0244 0.0936
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Onchocerca volvulus 0.0129 0.0187 0.2711
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1017
Echinococcus granulosus follistatin 0.005 0.0063 0.0316
Toxoplasma gondii patched family protein 0.0013 0.0004 0.0045
Brugia malayi RNA binding protein 0.0133 0.0193 0.1958
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0001 0.0000021581
Plasmodium vivax glutathione reductase, putative 0.0037 0.0042 0.0159
Leishmania major cathepsin L-like protease 0.0045 0.0054 0.0763
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.1667 0.2604 0.2603
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1017
Echinococcus granulosus FTZ F1 alpha 0.0047 0.0059 0.0292
Brugia malayi cytoplasmic intermediate filament protein 0.0019 0.0014 0.0138
Brugia malayi beta-lactamase 0.0074 0.01 0.1015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0019 0.0072
Onchocerca volvulus 0.0013 0.0004 0.0045
Schistosoma mansoni amine oxidase 0.0449 0.0689 0.3991
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0019 0.0094
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0449 0.0689 0.3991
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0116 0.0123
Brugia malayi Common central domain of tyrosinase family protein 0.0364 0.0556 0.5665
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.001 0.0132
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0004 0.0354
Loa Loa (eye worm) intermediate filament protein 0.0036 0.004 0.0405
Schistosoma mansoni coup transcription factor 0.0047 0.0059 0.034
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.0024 0.0239
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Trichomonas vaginalis esterase, putative 0.0074 0.01 0.2404
Entamoeba histolytica fatty acid elongase, putative 0.0216 0.0324 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0054 0.1299
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0054 0.0777
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Onchocerca volvulus 0.0013 0.0004 0.0045
Plasmodium falciparum kinesin-5 0.0166 0.0244 0.0936
Toxoplasma gondii exonuclease III APE 0.0012 0.0004 0.0044
Schistosoma mansoni follistatin 0.005 0.0063 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0027
Onchocerca volvulus 0.0074 0.01 0.1447
Trypanosoma brucei heat shock protein 84, putative 0.0019 0.0013 0.1283
Brugia malayi nuclear hormone receptor family member nhr-6 0.0022 0.0019 0.019
Onchocerca volvulus 0.0074 0.01 0.1447
Brugia malayi hypothetical protein 0.008 0.0109 0.1108
Plasmodium vivax heat shock protein 90, putative 0.0019 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0233
Schistosoma mansoni rab6-interacting 0.008 0.0109 0.0633
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1017
Echinococcus multilocularis protein dispatched 1 0.0101 0.0143 0.055
Echinococcus multilocularis 0.0094 0.0132 0.0507
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0063 0.0641
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) fibroinase 0.0012 0.0003 0.0019
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Toxoplasma gondii patched family protein 0.0013 0.0004 0.0045
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0019 0.0072
Echinococcus granulosus ferritin 0.0011 0.0002 0.0006
Schistosoma mansoni hypothetical protein 0.0085 0.0118 0.0684
Trichomonas vaginalis thioredoxin m(mitochondrial)-type, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0449 0.0689 0.7027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0019 0.0094
Plasmodium vivax heat shock protein 86, putative 0.0045 0.0056 0.0211
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.001 0.0009
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0058 0.0075 0.0761
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0047 0.0059 0.0292
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0003 0.0007
Toxoplasma gondii patched family protein 0.0013 0.0004 0.0045
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0233
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Brugia malayi Doublecortin family protein 0.008 0.0109 0.1108
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0054 0.1299
Plasmodium falciparum LCCL domain-containing protein 0.008 0.0109 0.0417
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0063 0.0908
Mycobacterium ulcerans bacterioferritin BfrB 0.0011 0.0002 0.0001
Leishmania major hypothetical protein, conserved 0.0074 0.01 0.143
Plasmodium vivax vivapain-2 0.0012 0.0003 0.0007
Brugia malayi hypothetical protein 0.0025 0.0024 0.0239
Brugia malayi photoreceptor-specific nuclear receptor 0.0047 0.0059 0.0592
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0167 0.0247 0.0952
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Onchocerca volvulus Protein patched homolog 0.0013 0.0004 0.0045
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0019
Wolbachia endosymbiont of Brugia malayi thioredoxin 0.0011 0.0002 0.0004
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0019 0.027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0019
Schistosoma mansoni heat shock protein 0.0045 0.0056 0.0322
Onchocerca volvulus Peroxidase homolog 0.0025 0.0024 0.034
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0097
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.01 0.058
Plasmodium falciparum thioredoxin reductase 0.0037 0.0042 0.0159
Plasmodium vivax multidomain scavenger receptor, putative 0.008 0.0109 0.0417
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0019 0.0013 0.0064
Echinococcus multilocularis mitogen activated protein kinase 3 0.0071 0.0095 0.0365
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0011 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0449 0.0689 0.7027
Leishmania major trypanothione reductase 0.0037 0.0042 0.0585
Echinococcus multilocularis heat shock protein 90 0.0036 0.0041 0.0156
Toxoplasma gondii heat shock protein HSP90 0.0045 0.0056 0.0795
Onchocerca volvulus Protein patched homolog 0.0013 0.0004 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0054 0.1299
Brugia malayi sodium-independent organic anion transporter family protein 0.0074 0.01 0.1017
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Brugia malayi CXXC zinc finger family protein 0.003 0.0031 0.0306
Mycobacterium tuberculosis Conserved protein 0.0074 0.01 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0022 0.0019 0.019
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0047 0.0059 0.0224
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.1667 0.2604 1
Echinococcus multilocularis heat shock protein 90 0.0045 0.0056 0.0212
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0449 0.0689 0.2646
Leishmania major heat shock protein, putative 0.0019 0.0013 0.0169
Onchocerca volvulus 0.0056 0.0072 0.1031
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0123 0.0474
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1017
Echinococcus granulosus cathepsin l cysteine peptidase 0.0012 0.0003 0.0009
Trypanosoma cruzi metacaspase, putative 0.0045 0.0054 0.078
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Onchocerca volvulus Peroxidase homolog 0.0025 0.0024 0.034
Echinococcus granulosus thyroid hormone receptor alpha 0.0022 0.0019 0.0094
Echinococcus multilocularis thioredoxin 1 0.0011 0.0002 0.0004
Trypanosoma brucei protein kinase, putative 0.0071 0.0095 0.9492
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0012 0.0004 0.0045
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0043 0.0212
Echinococcus multilocularis epidermal growth factor receptor 0.0163 0.0241 0.0928
Loa Loa (eye worm) hypothetical protein 0.0088 0.0123 0.125
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0354
Leishmania major cathepsin L-like protease 0.0045 0.0054 0.0763
Trichomonas vaginalis thioredoxin m(mitochondrial)-type, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0036 0.004 0.0405
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0472 0.0725 0.0778
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.0137 0.1388
Brugia malayi ecdysteroid receptor 0.0047 0.0059 0.0592
Trichomonas vaginalis heat shock protein, putative 0.0019 0.0013 0.0308
Giardia lamblia Kinase, CMGC MAPK 0.0071 0.0095 0.3872
Trypanosoma cruzi Heat shock protein 83, putative 0.0045 0.0056 0.0798
Schistosoma mansoni ferritin 0.0011 0.0002 0.0011
Onchocerca volvulus 0.0047 0.0059 0.0842
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0036 0.0041 0.0203
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0063 0.0908
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Toxoplasma gondii thioredoxin-like protein TLP1 0.0011 0.0002 0.0016
Echinococcus multilocularis expressed protein 0.005 0.0063 0.0243
Plasmodium falciparum heat shock protein 90, putative 0.0019 0.0013 0.0049
Trichomonas vaginalis ferritin, putative 0.0011 0.0002 0.0027
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0449 0.0689 1
Giardia lamblia Kinesin-5 0.0166 0.0244 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.008 0.0109 0.042
Echinococcus granulosus L aminoadipate semialdehyde 0.0056 0.0072 0.0357
Echinococcus granulosus heat shock protein 90 0.0036 0.0041 0.0203
Echinococcus granulosus lamin dm0 0.0036 0.004 0.02
Schistosoma mansoni steroid hormone receptor ad4bp 0.0047 0.0059 0.034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0133 0.0193 0.0744
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0047 0.0059 0.0224
Echinococcus granulosus nuclear factor of activated T cells 5 0.0164 0.0241 0.121
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0012 0.0004 0.0028
Echinococcus granulosus endoplasmin 0.0036 0.0041 0.0203
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0016 0.0009 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Brugia malayi Animal haem peroxidase family protein 0.0025 0.0024 0.0239
Echinococcus granulosus lysine specific histone demethylase 1A 0.0449 0.0689 0.3466
Onchocerca volvulus 0.0012 0.0003 0.0027
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0034 0.0127
Leishmania major metacaspase, putative 0.0045 0.0054 0.0765
Loa Loa (eye worm) hypothetical protein 0.0058 0.0075 0.0761
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.1667 0.2604 0.28
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0012 0.0004 0.0308
Echinococcus granulosus thioredoxin 0.0011 0.0002 0.0006
Echinococcus multilocularis expressed protein 0.0011 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) CYP4Cod1 0.0016 0.001 0.0093
Echinococcus granulosus cpg binding protein 0.0031 0.0033 0.0164
Echinococcus multilocularis ecdysone induced protein 78C 0.0047 0.0059 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0067 0.1597
Echinococcus multilocularis thioredoxin 0.0011 0.0002 0.0004
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Onchocerca volvulus 0.0013 0.0004 0.0045
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0071 0.0095 0.1356
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0133 0.0193 0.1119
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0004 0.0014
Brugia malayi sodium-independent organic anion transporter family protein 0.0074 0.01 0.1017
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0053 0.0067 0.0386
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0051
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0004 0.0036
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0001 0.0000012906
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Schistosoma mansoni hypothetical protein 0.0058 0.0075 0.0435
Echinococcus granulosus Polycystic kidney disease protein 0.008 0.0109 0.0546
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0016 0.0009 0.0008
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0019
Schistosoma mansoni survival motor neuron protein 0.0129 0.0187 0.1085
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Brugia malayi Patched related family protein 4 0.0013 0.0004 0.0032
Trypanosoma cruzi cruzipain precursor, putative 0.0045 0.0054 0.0779
Loa Loa (eye worm) hypothetical protein 0.0449 0.0689 0.7027
Plasmodium falciparum metacaspase-like protein 0.0045 0.0054 0.0206
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0024
Echinococcus multilocularis ferritin 0.0011 0.0002 0.0004
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0019 0.0013 0.0185
Schistosoma mansoni apoptosis regulator bax 0.0058 0.0075 0.0435
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Onchocerca volvulus 0.008 0.0109 0.1576
Trypanosoma cruzi metacaspase, putative 0.0045 0.0054 0.078
Echinococcus multilocularis caspase 8 0.0045 0.0054 0.0208
Trypanosoma cruzi major cysteine proteinase, putative 0.0035 0.0039 0.0561
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Echinococcus granulosus caspase 0.0167 0.0247 0.124
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0047 0.0059 0.034
Entamoeba histolytica fatty acid elongase, putative 0.0216 0.0324 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0019 0.0072
Brugia malayi hypothetical protein 0.0025 0.0024 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0123 0.2962
Brugia malayi Cytochrome P450 family protein 0.0016 0.001 0.0093
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0003 0.0058
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0059 0.0224
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0012 0.0004 0.0012
Schistosoma mansoni tyrosine kinase 0.0097 0.0137 0.0791
Echinococcus granulosus ecdysone induced protein 78C 0.0047 0.0059 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0059 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Echinococcus granulosus heat shock protein 90 0.0045 0.0056 0.0277
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0063 0.0641
Plasmodium falciparum metacaspase 1 0.0045 0.0054 0.0206
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Giardia lamblia Grp94/Hsp90 0.0036 0.0041 0.1657
Echinococcus granulosus Solute carrier organic anion transporter family 0.0074 0.01 0.0502
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0075 0.0102 0.0108
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) TAR-binding protein 0.0133 0.0193 0.1958
Brugia malayi steroid hormone receptor 0.0047 0.0059 0.0592
Onchocerca volvulus Cathepsin L homolog 0.0012 0.0003 0.0027
Brugia malayi nuclear receptor NHR-67 0.0022 0.0019 0.019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0017
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0024 0.0233
Onchocerca volvulus 0.0013 0.0004 0.0045
Echinococcus multilocularis caspase 3 0.0123 0.0177 0.068
Onchocerca volvulus 0.0013 0.0004 0.0045
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0012
Schistosoma mansoni hypothetical protein 0.0031 0.0034 0.0194
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Plasmodium falciparum glutathione reductase 0.0013 0.0004 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0028 0.066
Onchocerca volvulus Cathepsin F homolog 0.0012 0.0003 0.0027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.014 0.1424
Echinococcus multilocularis tar DNA binding protein 0.0133 0.0193 0.0742
Schistosoma mansoni cellular tumor antigen P53 0.0133 0.0193 0.1115
Schistosoma mansoni ap endonuclease 0.0012 0.0004 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0266 0.6424
Loa Loa (eye worm) beta-lactamase 0.0074 0.01 0.1015
Trypanosoma cruzi UDP-galactopyranose mutase 0.0449 0.0689 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0071 0.0095 0.137
Loa Loa (eye worm) hypothetical protein 0.0364 0.0556 0.5665
Onchocerca volvulus Putative organic anion transporter 0.0074 0.01 0.1447
Brugia malayi exodeoxyribonuclease III family protein 0.0012 0.0004 0.0031
Echinococcus granulosus epidermal growth factor receptor 0.0163 0.0241 0.1208
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0004 0.0035
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0004 0.0003
Onchocerca volvulus Peroxidasin homolog 0.0025 0.0024 0.034
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Mycobacterium ulcerans hypothetical protein 0.0074 0.01 0.0099
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0209 0.0313 0.1813
Schistosoma mansoni tyrosine kinase 0.0304 0.0462 0.2672
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Echinococcus granulosus thioredoxin 2 0.0011 0.0002 0.0006
Toxoplasma gondii transporter, major facilitator family protein 0.0074 0.01 0.1441
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1017
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0017 0.0011 0.0041
Schistosoma mansoni thioredoxin 0.0011 0.0002 0.0011
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0095 0.0134 0.0773
Loa Loa (eye worm) nuclear receptor NHR-67 0.0022 0.0019 0.019
Entamoeba histolytica kinesin, putative 0.0166 0.0244 0.7531
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0004 0.0014
Echinococcus multilocularis microtubule associated protein 2 0.0453 0.0696 0.2686
Loa Loa (eye worm) hypothetical protein 0.0045 0.0054 0.0548
Loa Loa (eye worm) cysteine protease 0.0012 0.0003 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0003 0.0019
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0042 0.0159
Loa Loa (eye worm) hypothetical protein 0.0449 0.0689 0.7027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Onchocerca volvulus 0.0025 0.0024 0.034
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0004 0.0085
Schistosoma mansoni hypothetical protein 0.0031 0.0034 0.0194
Echinococcus granulosus Niemann Pick C1 protein 0.0206 0.0308 0.1547
Trichomonas vaginalis heat shock protein, putative 0.0036 0.0041 0.0977
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0266 0.6424
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0035
Plasmodium falciparum endoplasmin, putative 0.0028 0.0028 0.0105
Brugia malayi nuclear hormone receptor 0.0047 0.0059 0.0592
Echinococcus granulosus transcription factor Dp 1 0.0026 0.0024 0.0119
Schistosoma mansoni ferritin 0.0011 0.0002 0.0011
Trypanosoma cruzi heat shock protein, putative 0.0019 0.0013 0.0185
Brugia malayi Steroid receptor seven-up type 2 0.0047 0.0059 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0012 0.0003 0.0045
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Onchocerca volvulus 0.0449 0.0689 1
Schistosoma mansoni hypothetical protein 0.0068 0.0091 0.0526
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0013 0.0004 0.0014
Echinococcus granulosus Thioredoxin fold 0.0011 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0056 0.0072 0.0724
Schistosoma mansoni ferritin light chain 0.0011 0.0002 0.0011
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0012 0.0004 0.0031
Onchocerca volvulus Cathepsin L homolog 0.0012 0.0003 0.0027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0036 0.004 0.0405
Schistosoma mansoni hypothetical protein 0.0511 0.0786 0.4553
Echinococcus multilocularis thioredoxin 2 0.0011 0.0002 0.0004
Brugia malayi ecdysone receptor 0.0022 0.0019 0.019
Leishmania major cathepsin L-like protease 0.0045 0.0054 0.0763
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0335
Treponema pallidum heat shock protein 90 0.0036 0.0041 1
Brugia malayi SPARC precursor 0.005 0.0063 0.0641
Brugia malayi nuclear hormone receptor 0.0022 0.0019 0.019
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Echinococcus granulosus nuclear receptor nhr 48 0.0022 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0019 0.0112
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0053 0.0067 0.0333
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0019 0.0013 0.0049
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0054 0.078
Brugia malayi Animal haem peroxidase family protein 0.0025 0.0024 0.0239
Plasmodium falciparum heat shock protein 90, putative 0.0019 0.0013 0.0049
Brugia malayi hypothetical protein 0.0634 0.0981 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0071 0.0095 0.1365
Loa Loa (eye worm) glutathione reductase 0.0037 0.0042 0.0422
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Echinococcus granulosus thioredoxin 1 0.0011 0.0002 0.0006
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0449 0.0689 0.3991
Mycobacterium tuberculosis Conserved hypothetical protein 0.0449 0.0689 0.074
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0058 0.0075 0.0375
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0042 0.0422
Plasmodium vivax vivapain-2 0.0012 0.0003 0.0007
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0131 0.1891
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0308 0.0468 0.1807
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0051
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0053 0.0067 0.2711
Schistosoma mansoni ferritin 0.0011 0.0002 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0059 0.034
Loa Loa (eye worm) hypothetical protein 0.0068 0.0091 0.092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Echinococcus multilocularis follistatin 0.005 0.0063 0.0243
Mycobacterium ulcerans thioredoxin TrxB1 0.0011 0.0002 0.0001
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0074 0.01 0.1017
Brugia malayi SWIRM domain containing protein 0.0449 0.0689 0.7027
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0071 0.0095 0.137
Echinococcus multilocularis mitogen activated protein kinase 0.0071 0.0095 0.0365
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0034 0.0127
Echinococcus multilocularis L aminoadipate semialdehyde 0.0056 0.0072 0.0274
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0003 0.0007
Trichomonas vaginalis thioredoxin f-type, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1017
Onchocerca volvulus 0.0025 0.0024 0.034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Echinococcus multilocularis thyroid hormone receptor alpha 0.0047 0.0059 0.0224
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0016 0.0009 0.0031
Schistosoma mansoni hypothetical protein 0.0129 0.0187 0.1085
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0016 0.0009 0.0008
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0047 0.0059 0.034
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0233
Echinococcus granulosus RUN 0.008 0.0109 0.0546
Loa Loa (eye worm) apoptosis regulator protein 0.0058 0.0075 0.0761
Mycobacterium ulcerans dehydrogenase 0.0449 0.0689 0.0689
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0035
Trypanosoma brucei metacaspase 0.0045 0.0054 0.5404
Trypanosoma brucei thioredoxin 0.0011 0.0002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0206 0.0308 0.3137
Schistosoma mansoni tyrosine kinase 0.0163 0.0241 0.1393
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.0137 0.0685
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0047 0.0059 0.0292
Echinococcus granulosus mitogen activated protein kinase 3 0.0071 0.0095 0.0475
Schistosoma mansoni cpg binding protein 0.0031 0.0033 0.0193
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0012 0.0003 0.0007
Schistosoma mansoni lipoxygenase 0.0308 0.0468 0.271
Trypanosoma brucei metacaspase 5, putative 0.0045 0.0054 0.5404
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0004
Onchocerca volvulus 0.0012 0.0003 0.0027
Echinococcus granulosus dnaJ subfamily B 0.0422 0.0647 0.3253
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0004 0.0051
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Echinococcus granulosus lipoxygenase domain containing protein 0.008 0.0109 0.0546
Brugia malayi hypothetical protein 0.0013 0.0004 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0051
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0054 0.0777
Echinococcus multilocularis tumor protein p63 0.0906 0.1408 0.5441
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0042 0.0043
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Echinococcus granulosus kinesin family 1 0.1275 0.1988 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0071 0.0095 0.137
Trypanosoma brucei metacaspase MCA3 0.0045 0.0054 0.5404
Brugia malayi Endoplasmin precursor 0.0045 0.0056 0.0561
Trichomonas vaginalis CMGC family protein kinase 0.0071 0.0095 0.2282
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0075 0.0102 0.1463
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0004 0.0014
Leishmania major cathepsin L-like protease 0.0012 0.0003 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0034 0.0335
Brugia malayi Animal haem peroxidase family protein 0.0025 0.0024 0.0239
Onchocerca volvulus 0.0364 0.0556 0.8062
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0012 0.0003 0.0007
Giardia lamblia Heat shock protein HSP 90-alpha 0.0036 0.0041 0.1657
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.01 0.0106
Onchocerca volvulus 0.0364 0.0556 0.8062
Echinococcus multilocularis insulin receptor 0.0097 0.0137 0.0526
Plasmodium falciparum heat shock protein 90 0.0045 0.0056 0.0211
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0063 0.0641
Schistosoma mansoni hypothetical protein 0.0085 0.0118 0.0684
Schistosoma mansoni peroxidasin 0.0025 0.0024 0.014
Echinococcus multilocularis epidermal growth factor receptor 0.0304 0.0462 0.1781
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0059 0.0224
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.01 0.2404
Brugia malayi hypothetical protein 0.0013 0.0004 0.0032
Entamoeba histolytica hypothetical protein 0.0016 0.0009 0.025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0012 0.0004 0.0095
Echinococcus multilocularis 0.0449 0.0689 0.2662
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.001 0.0093
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Brugia malayi nuclear receptor NHR-88 0.0047 0.0059 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0027
Brugia malayi hypothetical protein 0.0022 0.0019 0.019
Treponema pallidum thioredoxin (trx) 0.0011 0.0002 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0054 0.1299
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0266 0.6424
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0053 0.0067 0.0255
Echinococcus granulosus agrin 0.005 0.0063 0.0316
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Brugia malayi Patched protein homolog 1 0.0013 0.0004 0.0032
Onchocerca volvulus 0.0012 0.0003 0.0027
Echinococcus multilocularis lamin 0.0036 0.004 0.0153
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0058 0.0075 0.0375
Schistosoma mansoni thioredoxin 2 0.0011 0.0002 0.0011
Leishmania major cytochrome p450-like protein 0.0016 0.001 0.0116
Echinococcus granulosus Niemann Pick C1 protein 0.0295 0.0447 0.2247
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0364 0.0556 0.5665
Onchocerca volvulus 0.0074 0.01 0.1444
Treponema pallidum bacterioferrin (TpF1) 0.0011 0.0002 0.0278
Loa Loa (eye worm) ShTK domain-containing protein 0.0364 0.0556 0.5665
Brugia malayi RNA recognition motif domain containing protein 0.0133 0.0193 0.1958
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Brugia malayi protein C24B5.3 0.0013 0.0004 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0054 0.0206
Echinococcus multilocularis protein patched 0.0088 0.0123 0.0474
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0131 0.0139
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0075 0.0102 0.0393
Schistosoma mansoni amine oxidase 0.0449 0.0689 0.3991
Brugia malayi nuclear receptor RXR 0.0022 0.0019 0.019
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0004 0.0085
Schistosoma mansoni nuclear receptor 0.0022 0.0019 0.0112
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0004 0.0074
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0004 0.0354
Brugia malayi intermediate filament protein 0.0036 0.004 0.0405
Schistosoma mansoni microtubule-associated protein tau 0.0453 0.0696 0.4027
Brugia malayi CHE-14 protein 0.0088 0.0123 0.125
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.0032
Echinococcus multilocularis nuclear receptor nhr 48 0.0022 0.0019 0.0072
Brugia malayi secreted modular calcium-binding protein 1 0.005 0.0063 0.0641
Brugia malayi Furin-like cysteine rich region family protein 0.0304 0.0462 0.4702
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0059 0.0592
Trichomonas vaginalis thioredoxin f-type, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0047 0.0059 0.0592
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0414 1
Brugia malayi glutathione reductase 0.0037 0.0042 0.0422
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0193 0.1115
Entamoeba histolytica thioredoxin, putative 0.0011 0.0002 0.0035
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0163 0.0241 0.1208
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0019 0.019
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0012 0.0004 0.0002
Schistosoma mansoni topbp1 0.0011 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0059 0.0592
Chlamydia trachomatis oxoacyl-ACP synthase III 0.1667 0.2604 1
Mycobacterium tuberculosis Conserved protein 0.0074 0.01 0.0106
Echinococcus multilocularis Niemann Pick C1 protein 0.0206 0.0308 0.1189
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.01 0.058
Loa Loa (eye worm) hypothetical protein 0.0108 0.0154 0.1569
Schistosoma mansoni peroxidasin 0.0025 0.0024 0.014
Loa Loa (eye worm) hypothetical protein 0.008 0.0109 0.1108
Schistosoma mansoni hypothetical protein 0.008 0.0109 0.0633
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0022 0.0019 0.0112
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0044 0.0054 0.0311
Plasmodium falciparum protoporphyrinogen oxidase 0.0449 0.0689 0.2646
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0047 0.0059 0.0292
Schistosoma mansoni nuclear receptor 0.0022 0.0019 0.0112
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0059 0.0592
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Echinococcus granulosus thioredoxin mitochondrial 0.0011 0.0002 0.0006
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0058 0.0075 0.0435
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Entamoeba histolytica fatty acid elongase, putative 0.0216 0.0324 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0024 0.0136
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0206 0.0308 0.9501
Schistosoma mansoni ferritin light chain 0.0011 0.0002 0.0011
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0133 0.0193 0.1965
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0354
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0116 0.0123
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.01 0.0106
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0075 0.0102 0.0512
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0053 0.0067 0.6645
Loa Loa (eye worm) TK/EGFR protein kinase 0.0304 0.0462 0.4702
Trichomonas vaginalis heat shock protein, putative 0.0045 0.0056 0.1329
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0053 0.0067 0.1597
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.01 0.0106
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.1667 0.2604 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0024 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0047 0.0059 0.0592
Treponema pallidum NADH oxidase 0.0013 0.0004 0.0871
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0012 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0053 0.0067 0.0333
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.01 0.1444
Loa Loa (eye worm) tyrosinase 1 0.0364 0.0556 0.5665
Loa Loa (eye worm) hypothetical protein 0.0364 0.0556 0.5665
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Brugia malayi hypothetical protein 0.0013 0.0004 0.0032
Toxoplasma gondii heat shock protein 75, putative 0.0019 0.0013 0.0184
Loa Loa (eye worm) nuclear hormone receptor 0.0022 0.0019 0.019
Trypanosoma cruzi heat shock protein 90, putative 0.0045 0.0056 0.0798
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0016 0.0009 0.0031
Trypanosoma brucei trypanothione reductase 0.0037 0.0042 0.4158
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0059 0.0592
Brugia malayi Animal haem peroxidase family protein 0.0025 0.0024 0.0239
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0012 0.0004 0.0012
Leishmania major cathepsin L-like protease 0.0012 0.0003 0.0011
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0044 0.0054 0.0205
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Trichomonas vaginalis thioredoxin m(mitochondrial)-type, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.0024 0.0239
Echinococcus multilocularis GPCR, family 2 0.0031 0.0034 0.0127
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.0024 0.0239
Onchocerca volvulus Chorion peroxidase homolog 0.0025 0.0024 0.034
Entamoeba histolytica thioredoxin, putative 0.0011 0.0002 0.0035
Echinococcus granulosus geminin 0.0511 0.0786 0.3954
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0047 0.0059 0.0224
Echinococcus multilocularis endoplasmin 0.0036 0.0041 0.0156
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0019 0.0094
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Loa Loa (eye worm) hypothetical protein 0.0449 0.0689 0.7027
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.005 0.0063 0.0641
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.005 0.0063 0.0641
Leishmania major phosphopantetheinyl transferase-like protein 0.0016 0.0009 0.0101
Mycobacterium ulcerans heat shock protein 90 0.0036 0.0041 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0051
Echinococcus multilocularis RUN 0.008 0.0109 0.042
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0056 0.1698
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0071 0.0095 0.0963
Brugia malayi Cell death protein 3 precursor 0.0045 0.0054 0.0548
Onchocerca volvulus 0.0025 0.0024 0.034
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0058 0.0075 0.0288
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0074 0.01 0.0385
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0044 0.0054 0.1636
Schistosoma mansoni nuclear receptor nhr-48 0.0022 0.0019 0.0112
Loa Loa (eye worm) blistered cuticle protein 3 0.0025 0.0024 0.0239
Schistosoma mansoni lipoxygenase 0.0165 0.0243 0.1406
Brugia malayi conserved hypotetical protein 0.0022 0.0019 0.019
Schistosoma mansoni tyrosine kinase 0.0162 0.0238 0.1377
Onchocerca volvulus 0.0074 0.01 0.1447
Echinococcus granulosus epidermal growth factor receptor 0.0304 0.0462 0.2319
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0071 0.0095 0.137
Onchocerca volvulus Dual oxidase homolog 0.0025 0.0024 0.034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.01 1
Toxoplasma gondii hypothetical protein 0.0013 0.0004 0.0045
Trypanosoma cruzi heat shock protein 85, putative 0.0036 0.0041 0.0586
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.007 0.0094 0.0957
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0274 0.0414 0.422
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0116 0.0123
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0012 0.0004 0.0126
Schistosoma mansoni DNA ligase IV 0.0011 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.008 0.0109 0.1108
Schistosoma mansoni intermediate filament proteins 0.0036 0.004 0.0234
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.01 0.0384
Brugia malayi amine oxidase, flavin-containing family protein 0.0449 0.0689 0.7027
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0003 0.0007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0017 0.0011 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0047 0.0059 0.0592
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.01 0.05
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0036 0.0041 0.0586
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Echinococcus multilocularis kinesin family 1 0.1275 0.1988 0.7681
Mycobacterium ulcerans bacterioferritin BfrA 0.0011 0.0002 0.0001
Schistosoma mansoni tyrosine kinase 0.0162 0.0238 0.1377
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0075 0.0102 0.0593
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.01 0.1444
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0123 0.0617
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0056 0.0072 0.0415
Echinococcus multilocularis geminin 0.0511 0.0786 0.3037
Echinococcus multilocularis FTZ F1 alpha 0.0047 0.0059 0.0224
Leishmania major cysteine peptidase A (CPA) 0.0012 0.0003 0.0011
Plasmodium falciparum thioredoxin 1 0.0011 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Trypanosoma cruzi metacaspase, putative 0.0045 0.0054 0.078
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0027
Echinococcus multilocularis lamin dm0 0.0036 0.004 0.0153
Loa Loa (eye worm) kinesin-like protein KLP2 0.0166 0.0244 0.2487
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0001 0.0000021581
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0019 0.0014 0.0138
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Trichomonas vaginalis thioredoxin m(mitochondrial)-type, putative 0.0011 0.0002 0.0027
Schistosoma mansoni ap endonuclease 0.0012 0.0004 0.0022
Onchocerca volvulus 0.0012 0.0003 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0266 0.6424
Schistosoma mansoni zinc finger protein 0.0022 0.0019 0.0112
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0003 0.0007
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0022 0.0019 0.0072
Toxoplasma gondii histone lysine-specific demethylase 0.0449 0.0689 0.9959
Brugia malayi Niemann-Pick C1 protein precursor 0.0206 0.0308 0.3137
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Brugia malayi TAR-binding protein 0.0133 0.0193 0.1958
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0004 0.0045
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0034 0.0165
Schistosoma mansoni cpg binding protein 0.003 0.0031 0.0178
Mycobacterium ulcerans lipase LipD 0.0074 0.01 0.0099
Schistosoma mansoni endoplasmin 0.0045 0.0056 0.0322
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Chlamydia trachomatis thioredoxin 0.0011 0.0002 0.0004
Brugia malayi Kinesin motor domain containing protein 0.0166 0.0244 0.2487
Trichomonas vaginalis CMGC family protein kinase 0.0071 0.0095 0.2282
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0058 0.0075 0.0288
Brugia malayi hypothetical protein 0.008 0.0109 0.1108
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.01 0.0099
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0036 0.0041 0.0042
Trypanosoma brucei cytochrome P450, putative 0.0016 0.001 0.0914
Onchocerca volvulus 0.0074 0.01 0.1444
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Plasmodium vivax heat shock protein, putative 0.0019 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1015
Echinococcus multilocularis cpg binding protein 0.0031 0.0033 0.0126
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0414 1
Schistosoma mansoni hypothetical protein 0.0031 0.0034 0.0194
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0028 0.0028 0.0396
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0001 0.00000034502
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0024 0.0136
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.01 0.2404
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0056 0.0798
Mycobacterium ulcerans thioredoxin TrxC 0.0011 0.0002 0.0001
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0045 0.0054 0.0315
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.01 0.1015
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0009 0.0117
Echinococcus granulosus expressed protein 0.0011 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Mycobacterium ulcerans oxidoreductase 0.0449 0.0689 0.0689
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0016 0.0009 0.2
Onchocerca volvulus Glucosylceramidase homolog 0.018 0.0266 0.3857
Mycobacterium ulcerans thioredoxin TrxB1 0.0011 0.0002 0.0001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0003 0.0019
Toxoplasma gondii thioredoxin, putative 0.0011 0.0002 0.0016
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0056 0.5527
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.0137 0.0526
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0133 0.0193 0.1119
Loa Loa (eye worm) hypothetical protein 0.0099 0.014 0.1424
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0044 0.0054 0.054
Brugia malayi Protein kinase domain containing protein 0.0097 0.0137 0.1388
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0449 0.0689 0.2646
Echinococcus multilocularis cysteine protease 0.0012 0.0003 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0054 0.1299
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0022 0.0019 0.019
Mycobacterium tuberculosis Conserved protein 0.0074 0.01 0.0106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0133 0.0193 0.0969
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0047 0.0059 0.034
Loa Loa (eye worm) ctsf protein 0.0012 0.0003 0.0019
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0054 0.078
Loa Loa (eye worm) hypothetical protein 0.0449 0.0689 0.7027
Trichomonas vaginalis CMGC family protein kinase 0.0071 0.0095 0.2282
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Onchocerca volvulus 0.0013 0.0004 0.0045
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0274 0.0414 0.422
Onchocerca volvulus Putative organic anion transporter 0.0074 0.01 0.1447
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0414 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0047 0.0059 0.0592
Onchocerca volvulus 0.008 0.0109 0.1576
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Schistosoma mansoni hypothetical protein 0.0058 0.0075 0.0435
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0001 0.0000021581
Trypanosoma cruzi UDP-galactopyranose mutase 0.0449 0.0689 1
Mycobacterium tuberculosis Probable thioredoxin TrxB1 0.0011 0.0002 0.0000013575
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0075 0.0102 0.1038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0193 0.1115
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0059 0.0292
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0028 0.0028 0.0105
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0047 0.0059 0.0292
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0133 0.0193 0.1958
Plasmodium falciparum lipid/sterol:H+ symporter 0.0013 0.0004 0.0012
Toxoplasma gondii thioredoxin reductase 0.0037 0.0042 0.0598
Entamoeba histolytica acetyltransferase, GNAT family 0.0026 0.0024 0.0734
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0044 0.0054 0.0769
Schistosoma mansoni apoferritin-2 0.0011 0.0002 0.0011
Leishmania major cathepsin L-like protease 0.0012 0.0003 0.0011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0053 0.0067 0.0674
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0449 0.0689 0.2646
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0394
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0047 0.0059 0.034
Brugia malayi Patched related family protein 12 0.0013 0.0004 0.0032
Mycobacterium leprae Probable lipase LipE 0.0074 0.01 0.1444
Onchocerca volvulus 0.003 0.0031 0.0436
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Echinococcus granulosus caspase 2 0.0045 0.0054 0.027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Echinococcus multilocularis cysteine protease 0.0012 0.0003 0.0007
Schistosoma mansoni agrin 0.005 0.0063 0.0368
Mycobacterium ulcerans monoamine oxidase 0.0449 0.0689 0.0689
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.1667 0.2604 0.2603
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0034 0.0335
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0004 0.0074
Brugia malayi nuclear receptor RXR 0.0025 0.0024 0.0233
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0012 0.0004 0.0012
Echinococcus multilocularis Polycystic kidney disease protein 0.008 0.0109 0.042
Echinococcus multilocularis transcription factor Dp 1 0.0026 0.0024 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0071 0.0095 0.2282
Chlamydia trachomatis protoporphyrinogen oxidase 0.0449 0.0689 0.2646
Echinococcus granulosus GPCR family 2 0.0031 0.0034 0.0165
Schistosoma mansoni heat shock protein 0.0045 0.0056 0.0322
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0016 0.0009 0.0117
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Trichomonas vaginalis heat shock protein, putative 0.0036 0.0041 0.0977
Echinococcus granulosus mitogen activated protein kinase 0.0071 0.0095 0.0475
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0193 0.1115
Toxoplasma gondii heat shock protein 90, putative 0.0045 0.0056 0.0795
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0009 0.0812
Schistosoma mansoni tyrosine kinase 0.0163 0.0241 0.1393
Trichomonas vaginalis heat shock protein, putative 0.0036 0.0041 0.0977
Brugia malayi tailless protein 0.0022 0.0019 0.019
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0036 0.0041 0.0571
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Onchocerca volvulus Putative organic anion transporter 0.0074 0.01 0.1447
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0047 0.0059 0.0292
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0053 0.0067 0.0944
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Schistosoma mansoni hypothetical protein 0.0511 0.0786 0.4553
Loa Loa (eye worm) steroid hormone receptor 0.0047 0.0059 0.0592
Onchocerca volvulus Peroxidasin homolog 0.0025 0.0024 0.034
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0012 0.0003 0.0045
Loa Loa (eye worm) hypothetical protein 0.0634 0.0981 1
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0059 0.034
Onchocerca volvulus 0.0022 0.0019 0.027
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Mycobacterium leprae conserved hypothetical protein 0.0074 0.01 0.1444
Brugia malayi nuclear hormone receptor family member odr-7 0.0022 0.0019 0.019
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0056 0.0798
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0167 0.0247 0.124
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0024 0.0233
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0012 0.0003 0.0019
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0034 0.0335
Echinococcus granulosus intermediate filament protein 0.0036 0.004 0.02
Echinococcus multilocularis heat shock protein 0.0045 0.0056 0.0212
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Echinococcus multilocularis survival motor neuron protein 1 0.0634 0.0981 0.3789
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0053 0.0067 0.0386
Schistosoma mansoni heat shock protein 0.0019 0.0013 0.0078
Schistosoma mansoni cpg binding protein 0.0031 0.0033 0.0193
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0449 0.0689 0.2662
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0059 0.0592
Brugia malayi Blistered cuticle protein 3 0.0025 0.0024 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1015
Schistosoma mansoni ferritin 0.0011 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1015
Onchocerca volvulus Protein ultraspiracle homolog 0.0047 0.0059 0.0842
Toxoplasma gondii patched family protein 0.0013 0.0004 0.0045
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0059 0.034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0059 0.0592
Schistosoma mansoni RAR-like nuclear receptor 0.0047 0.0059 0.034
Schistosoma mansoni caspase-3 (C14 family) 0.0167 0.0247 0.143
Schistosoma mansoni hypothetical protein 0.0422 0.0647 0.3746
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0133 0.0193 0.0744
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0076 0.1089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0051
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0011 0.0002 0.0004
Brugia malayi hypothetical protein 0.0074 0.01 0.1017
Schistosoma mansoni caspase-7 (C14 family) 0.0167 0.0247 0.143
Plasmodium vivax metacaspase 1, putative 0.0045 0.0054 0.0206
Trypanosoma cruzi heat shock protein 90, putative 0.0036 0.0041 0.0586
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0071 0.0095 0.1356
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.0024 0.0239
Brugia malayi Myosin head containing protein 0.0013 0.0004 0.0032
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0451 0.0692 1
Entamoeba histolytica fatty acid elongase, putative 0.0216 0.0324 1
Echinococcus multilocularis thioredoxin, mitochondrial 0.0011 0.0002 0.0004
Schistosoma mansoni loxhd1 0.008 0.0109 0.0633
Mycobacterium tuberculosis Possible oxidoreductase 0.0449 0.0689 0.074
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0266 0.6424
Brugia malayi beta-lactamase family protein 0.0074 0.01 0.1015
Brugia malayi Peroxidasin 0.0025 0.0024 0.0239
Trypanosoma cruzi cysteine peptidase, putative 0.0012 0.0003 0.0027
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.01 0.0106
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0012 0.0004 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0047 0.0059 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0054 0.1299
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0047 0.0059 0.034
Brugia malayi protein C24B5.3 0.0013 0.0004 0.0032
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0019
Echinococcus granulosus ubiquitin specific protease 41 0.0053 0.0067 0.0333
Trypanosoma brucei heat shock protein, putative 0.0045 0.0056 0.5527
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.01 0.1015
Echinococcus granulosus peroxidasin 0.0025 0.0024 0.0118
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0004 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0116 0.0123
Onchocerca volvulus 0.0012 0.0003 0.0027
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0028 0.0028 0.0662
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0053 0.0067 0.2042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0004 0.0051
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0116 0.0123
Trichomonas vaginalis thioredoxin f-type, putative 0.0011 0.0002 0.0027
Loa Loa (eye worm) agrin synaptic family protein 0.005 0.0063 0.0641
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Echinococcus granulosus caspase 8 0.0045 0.0054 0.027
Echinococcus granulosus insulin receptor 0.0097 0.0137 0.0685
Loa Loa (eye worm) hypothetical protein 0.0133 0.0193 0.1958
Plasmodium vivax hypothetical protein, conserved 0.0074 0.01 0.0382
Schistosoma mansoni tyrosinase precursor 0.0364 0.0556 0.3218
Trypanosoma brucei Metacaspase-4 0.0045 0.0054 0.5404
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0047 0.0059 0.0592
Trypanosoma cruzi thioredoxin, putative 0.0011 0.0002 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0266 0.6424
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0004 0.0014
Onchocerca volvulus 0.0364 0.0556 0.8062
Brugia malayi hypothetical protein 0.0025 0.0024 0.0233
Brugia malayi hypothetical protein 0.0074 0.01 0.1017
Echinococcus multilocularis agrin 0.005 0.0063 0.0243
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0123 0.0617
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0045 0.0054 0.0548
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0414 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0054 0.1299
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.001 0.0093
Schistosoma mansoni hypothetical protein 0.0085 0.0118 0.0684
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0056 0.5527
Schistosoma mansoni organic anion transporter 0.0074 0.01 0.0581
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Schistosoma mansoni lamin 0.0036 0.004 0.0234
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.014 0.1424
Brugia malayi prostaglandin transporter 0.0074 0.01 0.1017
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0042 0.06
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0095 0.0134 0.0514
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0233
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.005 0.0063 0.0641
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.1667 0.2604 0.2603
Brugia malayi heat shock protein 90 0.0045 0.0056 0.0561
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0004 0.0035
Brugia malayi nuclear receptor NHR-88 0.0022 0.0019 0.019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0233
Echinococcus multilocularis dnaJ subfamily B 0.0422 0.0647 0.2498
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0063 0.0908
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.01 0.2404
Trypanosoma brucei Heat shock protein 83, putative 0.0045 0.0056 0.5527
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0282 0.6791
Echinococcus multilocularis musashi 0.0036 0.004 0.0153
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Brugia malayi acetyltransferase, GNAT family protein 0.0095 0.0134 0.1356
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0019 0.0112
Loa Loa (eye worm) hypothetical protein 0.0053 0.0067 0.0674
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0012 0.0004 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0116 0.1677
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1015
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Trypanosoma cruzi metacaspase, putative 0.0045 0.0054 0.078
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Trichomonas vaginalis bromodomain-containing protein, putative 0.0028 0.0028 0.0662
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0095 0.055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0083 0.048
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) ShTK domain-containing protein 0.0364 0.0556 0.5665
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Plasmodium vivax endoplasmin, putative 0.0045 0.0056 0.0211
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.5925 0.9295 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0045 0.0056 0.2255
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0001 0.0004
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Loa Loa (eye worm) hypothetical protein 0.005 0.0063 0.0641
Echinococcus granulosus histone acetyltransferase KAT2B 0.0028 0.0028 0.0138
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0001 0.000002758
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0047 0.0059 0.0224
Echinococcus multilocularis expressed conserved protein 0.0194 0.0289 0.1113
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0054 0.0779
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Onchocerca volvulus 0.0074 0.01 0.1444
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0047 0.0059 0.0592
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Echinococcus multilocularis peroxidasin 0.0025 0.0024 0.0091
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Brugia malayi hypothetical protein 0.0449 0.0689 0.7027
Mycobacterium tuberculosis Probable reductase 0.0084 0.0116 0.0123
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0004 0.0051
Echinococcus granulosus histone acetyltransferase KAT2B 0.0092 0.0129 0.0648
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0054 0.0777
Schistosoma mansoni lamin 0.0036 0.004 0.0234
Loa Loa (eye worm) DR-78 0.0022 0.0019 0.019
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0024 0.0233
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.01 0.2404
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Trypanosoma brucei metacaspase MCA2 0.0045 0.0054 0.5404
Echinococcus granulosus cathepsin L cysteine proteinase 0.0012 0.0003 0.0009
Brugia malayi ShTK domain containing protein 0.0364 0.0556 0.5665
Onchocerca volvulus 0.0074 0.01 0.1447
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0414 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0004 0.0014
Echinococcus granulosus cathepsin l1 0.0012 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.005 0.0063 0.0641
Onchocerca volvulus Bile acid receptor homolog 0.0047 0.0059 0.0842
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Brugia malayi Intermediate filament tail domain containing protein 0.0036 0.004 0.0405
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0133 0.0193 0.1965
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0003 0.0015
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0449 0.0689 0.2646
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0053 0.0067 0.1597
Giardia lamblia Histone acetyltransferase GCN5 0.0026 0.0024 0.0974
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0133 0.0193 0.0969
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.0004 0.0004
Plasmodium falciparum glutathione reductase 0.0037 0.0042 0.0159
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Plasmodium falciparum histone acetyltransferase GCN5 0.0026 0.0024 0.0091
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0164 0.0241 0.0929
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0047 0.0059 0.0592
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0131 0.0139
Echinococcus granulosus survival motor neuron protein 1 0.0634 0.0981 0.4933
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0019 0.0013 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0047 0.0059 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0003 0.0045
Onchocerca volvulus 0.0012 0.0003 0.0027
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0034 0.0165
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.01 0.0106
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0054 0.0779
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1015
Brugia malayi Animal haem peroxidase family protein 0.0025 0.0024 0.0239
Brugia malayi MAP kinase sur-1 0.0071 0.0095 0.0963
Echinococcus multilocularis lipoxygenase domain containing protein 0.008 0.0109 0.042
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0053 0.0067 0.0255
Brugia malayi Thioredoxin reductase 0.0037 0.0042 0.0422
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0044 0.0054 0.0267
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0019 0.027
Loa Loa (eye worm) heat shock protein 75 0.0019 0.0013 0.013
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0022 0.0019 0.0094
Schistosoma mansoni polycystin 1-related 0.008 0.0109 0.0633
Schistosoma mansoni tyrosine kinase 0.0162 0.0238 0.1377
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0027
Brugia malayi Cytochrome P450 family protein 0.0016 0.001 0.0093
Loa Loa (eye worm) endoplasmin 0.0045 0.0056 0.0561
Plasmodium vivax thioredoxin 1, putative 0.0011 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Brugia malayi beta-lactamase family protein 0.0074 0.01 0.1015
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0047 0.0059 0.0842
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0074 0.01 0.0385
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Entamoeba histolytica cysteine protease, putative 0.0012 0.0003 0.0058
Schistosoma mansoni tyrosinase precursor 0.0364 0.0556 0.3218
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0056 0.0072 0.0724
Echinococcus granulosus lamin 0.0036 0.004 0.02
Schistosoma mansoni endoplasmin 0.0045 0.0056 0.0322
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0075 0.0102 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0054 0.5393
Loa Loa (eye worm) hypothetical protein 0.0045 0.0054 0.0548
Toxoplasma gondii cathepsin CPL 0.0012 0.0003 0.0027
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0091 0.092
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.01 0.0106
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Mycobacterium ulcerans beta-lactamase 0.0074 0.01 0.0099
Schistosoma mansoni apoferritin-2 0.0011 0.0002 0.0011
Mycobacterium tuberculosis Thioredoxin TrxC (TRX) (MPT46) 0.0011 0.0002 0.0000013575
Toxoplasma gondii protease inhibitor PI2 0.005 0.0063 0.0908
Schistosoma mansoni rab6-interacting 0.008 0.0109 0.0633
Loa Loa (eye worm) heat shock protein 90 0.0045 0.0056 0.0561
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0308 0.0468 0.2353
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1015
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0123 0.125
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Onchocerca volvulus 0.0012 0.0003 0.0027
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0004 0.0051
Onchocerca volvulus 0.0022 0.0019 0.027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0075 0.0102 0.0102
Onchocerca volvulus 0.0364 0.0556 0.8062
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0024 0.0115
Brugia malayi orphan nuclear receptor NR2E1 0.0022 0.0019 0.019
Plasmodium vivax hypothetical protein, conserved 0.0449 0.0689 0.2646
Echinococcus multilocularis protoporphyrinogen oxidase 0.0449 0.0689 0.2662
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.01 0.0106
Schistosoma mansoni patched 1 0.0088 0.0123 0.0713
Echinococcus granulosus heat shock protein 0.0045 0.0056 0.0277
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0022 0.0019 0.0112
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0053 0.0067 0.0959
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Echinococcus granulosus caspase 3 0.0123 0.0177 0.0886
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Brugia malayi Hsp90 protein 0.0019 0.0013 0.013
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0044 0.0054 0.0769
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0054 0.0779
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0016 0.0009 0.0031
Schistosoma mansoni topbp1 0.0011 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0059 0.034
Treponema pallidum exodeoxyribonuclease (exoA) 0.0012 0.0004 0.0759
Brugia malayi hypothetical protein 0.0013 0.0004 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0027
Echinococcus granulosus expressed conserved protein 0.0194 0.0289 0.1449
Brugia malayi thioredoxin 0.0011 0.0002 0.0012
Onchocerca volvulus 0.0036 0.004 0.0576
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0071 0.0095 0.9492
Onchocerca volvulus 0.0036 0.004 0.0576
Entamoeba histolytica thioredoxin, putative 0.0011 0.0002 0.0035
Loa Loa (eye worm) patched family protein 0.0013 0.0004 0.0032
Brugia malayi sodium-independent organic anion transporter family protein 0.0074 0.01 0.1017
Schistosoma mansoni hypothetical protein 0.0058 0.0075 0.0435
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0044 0.0054 0.054
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0044 0.0054 0.0754
Toxoplasma gondii kinesin motor domain-containing protein 0.0166 0.0244 0.3524
Schistosoma mansoni retinoic acid receptor RXR 0.0047 0.0059 0.034
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0003 0.0058
Echinococcus granulosus tumor protein p63 0.0906 0.1408 0.7084
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0131 0.0139
Toxoplasma gondii ABC1 family protein 0.0074 0.01 0.1438
Echinococcus granulosus lysine specific histone demethylase 1A 0.0449 0.0689 0.3466
Echinococcus multilocularis caspase 2 0.0045 0.0054 0.0208
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0019
Onchocerca volvulus Cell death protein 3 homolog 0.0045 0.0054 0.078
Trypanosoma cruzi MFS transporter, putative 0.0074 0.01 0.1447
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Echinococcus multilocularis ubiquitin specific protease 41 0.0053 0.0067 0.0255
Echinococcus granulosus lipoxygenase domain containing protein 0.008 0.0109 0.0546
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0056 0.0798
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.6373 1 1
Loa Loa (eye worm) acetyltransferase 0.0095 0.0134 0.1356
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.01 0.0099
Loa Loa (eye worm) doublecortin family protein 0.008 0.0109 0.1108
Plasmodium falciparum cysteine proteinase falcipain 3 0.0012 0.0003 0.0007
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0004 0.0018
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0239
Schistosoma mansoni caspase-7 (C14 family) 0.0045 0.0054 0.0315
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0028 0.0028 0.0396
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.1017
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0074 0.01 0.0502
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0031 0.0306
Schistosoma mansoni kinesin eg-5 0.0166 0.0244 0.1415
Plasmodium vivax patched family protein, putative 0.0013 0.0004 0.0012
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0016 0.0009 0.0117
Onchocerca volvulus 0.0074 0.01 0.1447
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0022 0.0019 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0282 0.6791
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0044 0.0054 0.5326
Entamoeba histolytica fatty acid elongase, putative 0.0216 0.0324 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0041 0.0048 0.069
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.01 0.2404
Echinococcus multilocularis caspase 0.0167 0.0247 0.0952
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0043 0.0163
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0053 0.0067 0.0959
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0364 0.0556 0.5665
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0047 0.0059 0.0592
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0036 0.0041 0.0155
Leishmania major heat shock protein 83-1 0.0045 0.0056 0.0783
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0059 0.0292
Leishmania major UDP-galactopyranose mutase 0.0449 0.0689 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0003 0.0045
Leishmania major cathepsin L-like protease 0.0012 0.0003 0.0011
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0001 0.0000004492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0047 0.0059 0.0592
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0047 0.0059 0.0592
Echinococcus granulosus microtubule associated protein 2 0.0453 0.0696 0.3497
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0129 0.0187 0.1905
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Loa Loa (eye worm) RNA binding protein 0.0133 0.0193 0.1958
Echinococcus granulosus tar DNA binding protein 0.0133 0.0193 0.0966
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0047 0.0059 0.0592
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0004 0.0051
Trichomonas vaginalis thioredoxin, putative 0.0011 0.0002 0.0027
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0003 0.0015
Onchocerca volvulus 0.0133 0.0193 0.2786
Schistosoma mansoni organic anion transporter 0.0074 0.01 0.0581
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0449 0.0689 0.0689
Schistosoma mansoni hypothetical protein 0.0031 0.0034 0.0194
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0266 0.6424
Toxoplasma gondii Hsp90 domain-containing protein 0.0019 0.0013 0.0184
Schistosoma mansoni hypothetical protein 0.0085 0.0118 0.0684
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.005 0.0063 0.0908
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0056 0.1698
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0133 0.0193 0.1119
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Echinococcus multilocularis Niemann Pick C1 protein 0.0295 0.0447 0.1726
Onchocerca volvulus 0.005 0.0063 0.0912
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.014 0.1424
Schistosoma mansoni hypothetical protein 0.1109 0.1728 1
Trichomonas vaginalis endoplasmin, putative 0.0028 0.0028 0.066
Plasmodium vivax hypothetical protein, conserved 0.0449 0.0689 0.2646
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0019 0.019
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.1667 0.2604 1
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0364 0.0556 0.5665
Schistosoma mansoni tyrosine kinase 0.0097 0.0137 0.0791
Trypanosoma cruzi thioredoxin, putative 0.0011 0.0002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0047 0.0059 0.0592
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0193 0.1115
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.019
Brugia malayi Patched family protein 0.0013 0.0004 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0047 0.0059 0.0592
Brugia malayi hypothetical protein 0.0022 0.0019 0.019
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1657 0.2588 1
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0193 0.1115
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0026 0.0373
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0364 0.0556 0.5665

Activities

Activity type Activity value Assay description Source Reference
Stabilty (ADMET) < 10 % Drug metabolism in human HT-29 cells assessed as compound remaining at 18.5 kBq after 60 mins by reversed phase TLC analysis ChEMBL. 25281270
Stabilty (ADMET) = 80 % Stability in mouse plasma assessed as compound remaining at 74 KBq after 24 hrs by reversed phase TLC analysis ChEMBL. 25281270

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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