Detailed information for compound 941727

Basic information

Technical information
  • TDR Targets ID: 941727
  • Name: 1-(1,3-benzodioxol-5-ylmethyl)-3-[(4-methoxyp henyl)methyl]-4-oxoquinoline-2-carboxylic aci d
  • MW: 443.448 | Formula: C26H21NO6
  • H donors: 1 H acceptors: 3 LogP: 4.64 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)Cc1c(C(=O)O)n(Cc2ccc3c(c2)OCO3)c2c(c1=O)cccc2
  • InChi: 1S/C26H21NO6/c1-31-18-9-6-16(7-10-18)12-20-24(26(29)30)27(21-5-3-2-4-19(21)25(20)28)14-17-8-11-22-23(13-17)33-15-32-22/h2-11,13H,12,14-15H2,1H3,(H,29,30)
  • InChiKey: DVWZRWWQAUPCBI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(1,3-benzodioxol-5-ylmethyl)-3-[(4-methoxyphenyl)methyl]-4-oxo-quinoline-2-carboxylic acid
  • 1-(1,3-benzodioxol-5-ylmethyl)-3-[(4-methoxyphenyl)methyl]-4-oxo-2-quinolinecarboxylic acid
  • 1-(1,3-benzodioxol-5-ylmethyl)-4-keto-3-(4-methoxybenzyl)quinaldic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0058 0.0451 0.1109
Loa Loa (eye worm) ctsf protein 0.0206 0.3128 0.7695
Schistosoma mansoni inhibitor of apoptosis protein 0.0092 0.1054 0.1054
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.1259 0.366
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0092 0.1054 0.2593
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0086
Entamoeba histolytica cysteine proteinase 2 0.0103 0.1259 0.366
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Loa Loa (eye worm) hypothetical protein 0.006 0.0475 0.1168
Onchocerca volvulus Deterin homolog 0.0092 0.1054 0.3325
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0451 0.0451
Onchocerca volvulus 0.0206 0.3128 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Onchocerca volvulus 0.0045 0.0205 0.0592
Brugia malayi cathepsin F-like cysteine proteinase 0.006 0.0475 0.1168
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Schistosoma mansoni chromobox protein 0.0045 0.0205 0.0205
Loa Loa (eye worm) TK/ROR protein kinase 0.0035 0.0021 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0529
Plasmodium vivax unspecified product 0.0043 0.0179 0.051
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0179 0.0446
Loa Loa (eye worm) hypothetical protein 0.0042 0.016 0.0395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0147 0.2049 0.6503
Loa Loa (eye worm) hypothetical protein 0.0043 0.0179 0.0441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Entamoeba histolytica cysteine proteinase, putative 0.0206 0.3128 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0179 0.0179
Echinococcus granulosus tar DNA binding protein 0.0062 0.0519 0.05
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0043 0.0179 0.0446
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0067 0.0602 0.0582
Loa Loa (eye worm) hypothetical protein 0.0067 0.0602 0.1481
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0519 0.0519
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0086
Plasmodium falciparum serine repeat antigen 8 0.0043 0.0179 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0179 0.0446
Brugia malayi cathepsin B-like cysteine proteinase 0.0173 0.2523 0.6206
Onchocerca volvulus Cathepsin F homolog 0.0206 0.3128 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0206 0.3128 0.7695
Schistosoma mansoni chromobox protein 0.0586 1 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0041 0.0021
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0519 0.05
Loa Loa (eye worm) fibroinase 0.0206 0.3128 0.7695
Loa Loa (eye worm) heterochromatin protein 1 0.0045 0.0205 0.0503
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0179 0.0446
Echinococcus granulosus cathepsin l1 0.0206 0.3128 0.3114
Entamoeba histolytica hypothetical protein 0.0045 0.0205 0.0086
Toxoplasma gondii cathepsin CPC2 0.0043 0.0179 0.051
Brugia malayi hypothetical protein 0.0045 0.0205 0.0503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0179 0.0446
Brugia malayi fibroinase precursor 0.0043 0.0179 0.0441
Brugia malayi Cathepsin L-like precursor 0.0147 0.2049 0.504
Echinococcus granulosus cathepsin l cysteine peptidase 0.0206 0.3128 0.3114
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0092 0.1054 0.1035
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0043 0.0179 0.051
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0043 0.0179 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0045 0.0205 0.0503
Trypanosoma brucei cysteine peptidase C (CPC) 0.0083 0.0904 0.2795
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Brugia malayi SET domain containing protein 0.0045 0.0205 0.0503
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0463 0.114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0206 0.3128 0.3114
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0103 0.1259 0.3984
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0043 0.0179 0.051
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0043 0.0179 0.0441
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0179 0.051
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0067 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0052 0.0327 0.0805
Echinococcus granulosus cathepsin L cysteine protease 0.0103 0.1259 0.124
Plasmodium falciparum cysteine proteinase falcipain 3 0.0206 0.3128 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0043 0.0179 0.0179
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0519 0.0519
Schistosoma mansoni cathepsin F (C01 family) 0.0206 0.3128 0.3128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0322 0.0322
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0451 0.0431
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0045 0.0205 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0179 0.0446
Loa Loa (eye worm) cysteine protease 0.0206 0.3128 0.7695
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0322 0.0302
Onchocerca volvulus 0.0206 0.3128 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0216 0.0216
Brugia malayi Matrixin family protein 0.0042 0.016 0.0395
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0322 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0904 0.2795
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0043 0.0179 0.051
Plasmodium falciparum serine repeat antigen 7 0.0043 0.0179 0.051
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0043 0.0179 0.051
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0519 0.0519
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0021 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0205 0.0529
Trichomonas vaginalis Heterochromatin protein, putative 0.0045 0.0205 0.0529
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0206 0.3128 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0041 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0216 0.0196
Brugia malayi beta-lactamase family protein 0.0036 0.0041 0.0102
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Loa Loa (eye worm) hypothetical protein 0.0043 0.0179 0.0441
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0179 0.0179
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0451 0.0431
Brugia malayi Hemopexin family protein 0.006 0.048 0.1182
Echinococcus granulosus cathepsin L 0.0103 0.1259 0.124
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0173 0.2523 0.2523
Brugia malayi Cathepsin L-like precursor 0.0206 0.3128 0.7695
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0045 0.0205 0.0184
Toxoplasma gondii preprocathepsin c precursor, putative 0.0043 0.0179 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0216 0.0196
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0045 0.0205 0.0205
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0041 0.0102
Loa Loa (eye worm) RNA binding protein 0.0062 0.0519 0.1278
Echinococcus granulosus chromobox protein 1 0.0045 0.0205 0.0184
Trypanosoma cruzi cysteine peptidase, putative 0.0206 0.3128 1
Plasmodium vivax vivapain-2 0.0206 0.3128 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.1259 0.3943
Echinococcus multilocularis chromobox protein 1 0.0045 0.0205 0.0184
Loa Loa (eye worm) hypothetical protein 0.0043 0.0179 0.0441
Onchocerca volvulus 0.0206 0.3128 1
Loa Loa (eye worm) cathepsin B 0.0083 0.0904 0.2224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Plasmodium vivax vivapain-2 0.0206 0.3128 1
Trypanosoma cruzi cysteine peptidase, putative 0.0206 0.3128 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Plasmodium vivax unspecified product 0.006 0.0475 0.1461
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0216 0.0532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Loa Loa (eye worm) hypothetical protein 0.0049 0.0282 0.0694
Brugia malayi cathepsin L precursor 0.0043 0.0179 0.0441
Onchocerca volvulus Matrilysin homolog 0.0094 0.1092 0.3449
Toxoplasma gondii ABC1 family protein 0.0036 0.0041 0.0067
Brugia malayi jmjC domain containing protein 0.0094 0.109 0.2681
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0519 0.1278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0147 0.2049 0.6503
Loa Loa (eye worm) hypothetical protein 0.0043 0.0179 0.0441
Brugia malayi Matrixin family protein 0.0102 0.1245 0.3064
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0179 0.0446
Loa Loa (eye worm) hypothetical protein 0.0049 0.028 0.0689
Plasmodium falciparum serine repeat antigen 6 0.0043 0.0179 0.051
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0519 0.1278
Echinococcus multilocularis cathepsin L cysteine protease 0.0206 0.3128 0.3114
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0052 0.0327 0.0805
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Brugia malayi cathepsin L-like precursor 0.0147 0.2049 0.504
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Schistosoma mansoni hypothetical protein 0.0338 0.5514 0.5514
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Echinococcus granulosus cathepsin b 0.0173 0.2523 0.2507
Echinococcus multilocularis geminin 0.0338 0.5514 0.5505
Echinococcus multilocularis cysteine protease 0.0206 0.3128 0.3114
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0322 0.0322
Toxoplasma gondii cathepsin CPC1 0.0043 0.0179 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0179 0.0446
Loa Loa (eye worm) hypothetical protein 0.0152 0.214 0.5265
Loa Loa (eye worm) MBCTL1 0.0058 0.0451 0.1109
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0043 0.0179 0.0446
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0179 0.0446
Schistosoma mansoni chromobox protein 0.0045 0.0205 0.0205
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.1259 0.3096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Echinococcus multilocularis cathepsin L 0.0043 0.0179 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0043 0.0179 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0179 0.0446
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.1259 0.1259
Echinococcus granulosus Chromo domain 0.0045 0.0205 0.0184
Trichomonas vaginalis hypothetical protein 0.0045 0.0205 0.0529
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Onchocerca volvulus 0.006 0.048 0.1479
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0045 0.0205 0.0592
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0179 0.0441
Brugia malayi Cathepsin L-like precursor 0.0206 0.3128 0.7695
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Plasmodium vivax vivapain-1 0.0103 0.1259 0.3984
Schistosoma mansoni cathepsin F (C01 family) 0.0206 0.3128 0.3128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0045 0.0205 0.0592
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0216 0.0532
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0043 0.0179 0.051
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0021 0.0053
Echinococcus granulosus chromobox protein 1 0.0045 0.0205 0.0184
Loa Loa (eye worm) hypothetical protein 0.0206 0.3128 0.7695
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0021 0.0021
Brugia malayi Heterochromatin protein 1 0.0045 0.0205 0.0503
Onchocerca volvulus Cathepsin L homolog 0.0206 0.3128 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.0102
Onchocerca volvulus 0.0036 0.0041 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.0102
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0043 0.0179 0.051
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0205 0.0529
Brugia malayi cathepsin Z-like cysteine proteinase 0.0043 0.0179 0.0441
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0173 0.2523 0.8052
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0041 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.028 0.0689
Brugia malayi Matrixin family protein 0.0042 0.016 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Loa Loa (eye worm) hypothetical protein 0.0042 0.016 0.0395
Plasmodium vivax vivapain-3 0.0103 0.1259 0.3984
Schistosoma mansoni cathepsin B (C01 family) 0.0043 0.0179 0.0179
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0529
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0069 0.0977
Echinococcus multilocularis cathepsin L cysteine protease 0.0206 0.3128 0.3114
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0322 0.0302
Schistosoma mansoni hypothetical protein 0.006 0.048 0.048
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0042 0.016 0.016
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0179 0.0179
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0083 0.0904 0.2843
Entamoeba histolytica cysteine protease, putative 0.0206 0.3128 1
Plasmodium falciparum serine repeat antigen 9 0.0043 0.0179 0.051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0202 0.3049 0.3034
Loa Loa (eye worm) hypothetical protein 0.0258 0.4065 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.1259 0.1259
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0179 0.0179
Trypanosoma cruzi major cysteine proteinase, putative 0.0043 0.0179 0.051
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0043 0.0179 0.051
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0092 0.1054 0.1035
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0205 0.0592
Loa Loa (eye worm) hypothetical protein 0.0035 0.0021 0.0051
Brugia malayi Papain family cysteine protease containing protein 0.0206 0.3128 0.7695
Brugia malayi jmjC domain containing protein 0.0035 0.0021 0.0053
Loa Loa (eye worm) matrix metalloproteinase 0.0042 0.016 0.0395
Echinococcus multilocularis cathepsin L 0.0103 0.1259 0.124
Loa Loa (eye worm) hypothetical protein 0.0092 0.1054 0.2593
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Onchocerca volvulus 0.0152 0.214 0.6821
Brugia malayi Tachykinin-like peptides receptor 99D 0.0258 0.4065 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0179 0.0446
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0043 0.0179 0.0441
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.028 0.0689
Loa Loa (eye worm) hypothetical protein 0.006 0.0475 0.1168
Schistosoma mansoni cathepsin s 0.006 0.0475 0.0475
Plasmodium vivax serine-repeat antigen (SERA) 0.0043 0.0179 0.051
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Loa Loa (eye worm) hypothetical protein 0.0072 0.0704 0.1732
Brugia malayi Cathepsin L-like precursor 0.0206 0.3128 0.7695
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Plasmodium falciparum cysteine proteinase falcipain 1 0.0103 0.1259 0.3984
Loa Loa (eye worm) beta-lactamase 0.0036 0.0041 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Loa Loa (eye worm) hypothetical protein 0.0067 0.0602 0.1481
Onchocerca volvulus 0.0043 0.0179 0.051
Schistosoma mansoni cathepsin C 0.0043 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0147 0.2049 0.504
Brugia malayi beta-lactamase 0.0036 0.0041 0.0102
Loa Loa (eye worm) matrixin family protein 0.0102 0.1245 0.3064
Onchocerca volvulus 0.0045 0.0205 0.0592
Echinococcus multilocularis chromobox protein 2 0.0586 1 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0322 0.0793
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0322 0.0793
Brugia malayi cathepsin Z-like cysteine proteinase 0.0043 0.0179 0.0441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Echinococcus granulosus cathepsin L 0.0043 0.0179 0.0159
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Loa Loa (eye worm) hypothetical protein 0.0147 0.2049 0.504
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0043 0.0179 0.0446
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0206 0.3128 0.3114
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0043 0.0179 0.0179
Brugia malayi hypothetical protein 0.0152 0.214 0.5265
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0179 0.0441
Echinococcus granulosus cysteine protease 0.0103 0.1259 0.124
Onchocerca volvulus 0.0051 0.0322 0.0971
Leishmania major hypothetical protein, conserved 0.0036 0.0041 0.0067
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0205 0.0529
Plasmodium falciparum serine repeat antigen 1 0.0043 0.0179 0.051
Mycobacterium leprae PROBABLE HYDROLASE 0.0052 0.0327 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0045 0.0205 0.0205
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.1259 0.366
Mycobacterium ulcerans hydrolase 0.0052 0.0327 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.3523 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0045 0.0205 0.0184
Entamoeba histolytica cysteine proteinase 1, putative 0.0103 0.1259 0.366
Giardia lamblia Cathepsin B precursor 0.0083 0.0904 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0045 0.0205 0.0184
Schistosoma mansoni cathepsin F (C01 family) 0.0147 0.2049 0.2049
Onchocerca volvulus 0.0206 0.3128 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Entamoeba histolytica hypothetical protein 0.0045 0.0205 0.0086
Loa Loa (eye worm) hypothetical protein 0.006 0.0475 0.1168
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0041 0.0102
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0043 0.0179 0.051
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0115 0.0095
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0179 0.0441
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0322 0.0971
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0322 0.0322
Loa Loa (eye worm) CHromoDomain protein family member 0.0045 0.0205 0.0503
Onchocerca volvulus 0.0092 0.1054 0.3325
Giardia lamblia Cathepsin B precursor 0.0083 0.0904 1
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0904 0.0904
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Brugia malayi chromobox protein homolog 3 0.0045 0.0205 0.0503
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.0102
Trypanosoma cruzi major cysteine proteinase, putative 0.0043 0.0179 0.051
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0322 0.0302
Brugia malayi Matrixin family protein 0.0042 0.016 0.0395
Echinococcus granulosus lysine specific histone demethylase 1A 0.0067 0.0602 0.0582
Loa Loa (eye worm) hypothetical protein 0.0043 0.0179 0.0441
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.1259 0.3984
Loa Loa (eye worm) helicase 0.0045 0.0205 0.0503
Echinococcus multilocularis Chromo domain 0.0045 0.0205 0.0184
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0519 0.0519
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.1259 0.3943
Brugia malayi Cathepsin L-like precursor 0.0206 0.3128 0.7695
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0021 0.0001
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0173 0.2523 0.2523
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.028 0.0689
Plasmodium falciparum heterochromatin protein 1 0.0045 0.0205 0.0592
Onchocerca volvulus 0.0036 0.0041 0.0067
Echinococcus granulosus Chromobox protein 3 0.0045 0.0205 0.0184
Loa Loa (eye worm) hypothetical protein 0.0092 0.1054 0.2593
Echinococcus multilocularis cysteine protease 0.0206 0.3128 0.3114
Brugia malayi Cathepsin L-like precursor 0.006 0.0475 0.1168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.1259 0.3943
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Trypanosoma cruzi cysteine peptidase, putative 0.0103 0.1259 0.3984
Brugia malayi Protein cec-1. 0.0045 0.0205 0.0503
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0529
Onchocerca volvulus 0.0045 0.0205 0.0592
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0202 0.3049 0.3034
Schistosoma mansoni hypothetical protein 0.0035 0.0021 0.0021
Toxoplasma gondii cathepsin B 0.0083 0.0904 0.2843
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Trypanosoma cruzi cruzipain precursor, putative 0.0206 0.3128 1
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.1259 0.366
Plasmodium falciparum serine repeat antigen 5 0.0043 0.0179 0.051
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0179 0.0441
Schistosoma mansoni hypothetical protein 0.0045 0.0205 0.0205
Schistosoma mansoni hypothetical protein 0.0338 0.5514 0.5514
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.109 0.1071
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Schistosoma mansoni cathepsin S (C01 family) 0.0043 0.0179 0.0179
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.109 0.1071
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0206 0.3128 0.7695
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0045 0.0205 0.0205
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Toxoplasma gondii cathepsin CPL 0.0206 0.3128 1
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0205 0.0529
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0086
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0045 0.0205 0.0592
Trypanosoma cruzi cruzipain precursor, putative 0.006 0.0475 0.1461
Onchocerca volvulus 0.0206 0.3128 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0043 0.0179 0.051
Loa Loa (eye worm) hypothetical protein 0.0043 0.0179 0.0441
Loa Loa (eye worm) papain family cysteine protease containing protein 0.006 0.0475 0.1168
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0206 0.3128 1
Plasmodium vivax heterochromatin protein 1, putative 0.0045 0.0205 0.0592
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0179 0.0446
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0216 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0173 0.2523 0.2523
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Plasmodium falciparum serine repeat antigen 2 0.0043 0.0179 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0206 0.3128 1
Onchocerca volvulus Cathepsin L homolog 0.0206 0.3128 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0451 0.0431
Echinococcus multilocularis neuropeptide FF receptor 2 0.0258 0.4065 0.4052
Loa Loa (eye worm) hypothetical protein 0.0042 0.016 0.0395
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0205 0.0529
Schistosoma mansoni hypothetical protein 0.0312 0.5031 0.5031
Plasmodium vivax serine-repeat antigen (SERA) 0.0043 0.0179 0.051
Echinococcus granulosus geminin 0.0338 0.5514 0.5505
Onchocerca volvulus 0.0072 0.0704 0.2199
Trypanosoma cruzi cysteine peptidase, putative 0.0206 0.3128 1
Brugia malayi SWIRM domain containing protein 0.0072 0.0704 0.1732
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0179 0.0446
Echinococcus granulosus cathepsin l1 0.0147 0.2049 0.2032
Brugia malayi MH2 domain containing protein 0.0118 0.1538 0.3783
Brugia malayi Protein kinase domain containing protein 0.0035 0.0021 0.0051
Trypanosoma cruzi cysteine peptidase, putative 0.006 0.0475 0.1461
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0154 0.2177 0.2161
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Onchocerca volvulus 0.0147 0.2049 0.6526
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.1259 0.3984
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0179 0.0441
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Plasmodium vivax unspecified product 0.0103 0.1259 0.3984
Brugia malayi CHD4 protein 0.0045 0.0205 0.0503
Brugia malayi beta-lactamase family protein 0.0036 0.0041 0.0102
Onchocerca volvulus 0.0042 0.016 0.045
Brugia malayi Associated with TFs and helicases family protein 0.0045 0.0205 0.0503
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0173 0.2523 0.2523
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Leishmania major cysteine peptidase A (CPA) 0.0206 0.3128 1
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0205 0.0529
Echinococcus multilocularis Chromobox protein 3 0.0045 0.0205 0.0184
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0092 0.1054 0.2593
Plasmodium falciparum serine repeat antigen 3 0.0043 0.0179 0.051
Brugia malayi TAR-binding protein 0.0062 0.0519 0.1278
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0451 0.1109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0206 0.3128 1
Brugia malayi cathepsin L-like cysteine proteinase 0.0043 0.0179 0.0441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Onchocerca volvulus 0.0206 0.3128 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Echinococcus granulosus cathepsin b 0.0173 0.2523 0.2507
Loa Loa (eye worm) matrixin family protein 0.0094 0.1092 0.2688
Brugia malayi Cathepsin L-like cysteine proteinase 0.0147 0.2049 0.504
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.0102
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0205 0.0592
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.006 0.0475 0.1168
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0529
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0451 0.0431
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0045 0.0205 0.0205
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Onchocerca volvulus 0.0206 0.3128 1
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0205 0.0529
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0741 0.0741
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0206 0.3128 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0041 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0205 0.0529
Plasmodium falciparum serine repeat antigen 4 0.0043 0.0179 0.051
Echinococcus multilocularis cathepsin b 0.0173 0.2523 0.2507
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0206 0.3128 1
Echinococcus multilocularis cathepsin b 0.0173 0.2523 0.2507
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0052 0.0327 0.0821
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0205 0.0529
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.1259 0.1259
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0154 0.2177 0.2161
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0205 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0043 0.0179 0.0446
Brugia malayi Cathepsin L-like precursor 0.0206 0.3128 0.7695
Leishmania major cathepsin L-like protease 0.0206 0.3128 1
Giardia lamblia Cathepsin B precursor 0.0083 0.0904 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0205 0.0592
Brugia malayi M-phase phosphoprotein, mpp8 0.0045 0.0205 0.0503
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0083 0.0904 0.2843
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0179 0.0179
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0041 0.0067
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0205 0.0529
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Echinococcus multilocularis chromobox protein 1 0.0045 0.0205 0.0184
Trypanosoma cruzi cysteine peptidase, putative 0.0206 0.3128 1
Brugia malayi RNA binding protein 0.0062 0.0519 0.1278
Brugia malayi cathepsin F-like cysteine proteinase 0.0043 0.0179 0.0441
Loa Loa (eye worm) hypothetical protein 0.0147 0.2049 0.504
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0043 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0216 0.0196
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0519 0.1278
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0519 0.0519
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0043 0.0179 0.051
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.1538 0.3783
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Brugia malayi Valyl-tRNA synthetase 0.0045 0.0205 0.0503
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.1538 0.3783
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0179 0.0446
Brugia malayi mbt repeat family protein 0.0051 0.0322 0.0793
Echinococcus granulosus inhibitor of apoptosis protein 0.0092 0.1054 0.1035
Onchocerca volvulus 0.0036 0.0041 0.0067
Echinococcus granulosus jumonji domain containing protein 0.004 0.0115 0.0095
Schistosoma mansoni chromobox protein 0.0045 0.0205 0.0205
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0092 0.1054 0.1054
Echinococcus multilocularis inhibitor of apoptosis protein 0.0092 0.1054 0.1035
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.1259 0.3096
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0043 0.0179 0.051
Onchocerca volvulus Matrix metalloproteinase homolog 0.0094 0.1092 0.3449
Loa Loa (eye worm) hypothetical protein 0.0173 0.2523 0.6206
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0503
Entamoeba histolytica cysteine proteinase, putative 0.0206 0.3128 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0045 0.0205 0.0184
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0205 0.0592
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0043 0.0179 0.051
Schistosoma mansoni hypothetical protein 0.0092 0.1054 0.1054
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0021 0.0001
Entamoeba histolytica hypothetical protein 0.0045 0.0205 0.0086
Echinococcus granulosus cathepsin L cysteine proteinase 0.0206 0.3128 0.3114
Brugia malayi Cathepsin L-like precursor 0.0147 0.2049 0.504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0179 0.0446
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0179 0.0446
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0045 0.0205 0.0592
Trypanosoma cruzi cysteine protease, putative 0.0103 0.1259 0.3984
Brugia malayi Kringle domain containing protein 0.0035 0.0021 0.0051
Onchocerca volvulus Matrilysin homolog 0.0042 0.016 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0206 0.3128 1
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.1259 0.366
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0147 0.2049 0.6526
Entamoeba histolytica cysteine proteinase, putative 0.0147 0.2049 0.634
Brugia malayi Matrixin family protein 0.0042 0.016 0.0395
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Brugia malayi mbt repeat family protein 0.0051 0.0322 0.0793
Entamoeba histolytica cysteine protease, putative 0.0103 0.1259 0.366
Brugia malayi Cathepsin L-like precursor 0.0206 0.3128 0.7695
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.1259 0.3943
Echinococcus granulosus neuropeptide FF receptor 2 0.0258 0.4065 0.4052

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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