Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1104 | 0.2108 | 0.4054 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2053 | 0.5201 | 0.5201 |
Echinococcus granulosus | cathepsin L | 0.1104 | 0.2108 | 0.2108 |
Plasmodium vivax | vivapain-2 | 0.2053 | 0.5201 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1104 | 0.2108 | 0.2108 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Plasmodium vivax | vivapain-3 | 0.1104 | 0.2108 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.2053 | 0.5201 | 1 |
Schistosoma mansoni | cathepsin s | 0.0647 | 0.0622 | 0.0622 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0563 | 0.0348 | 0.0348 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1406 | 0.3093 | 0.5947 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.2053 | 0.5201 | 0.5201 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0563 | 0.0348 | 0.0348 |
Brugia malayi | Cathepsin L-like precursor | 0.2053 | 0.5201 | 0.5201 |
Brugia malayi | Cathepsin L-like precursor | 0.2053 | 0.5201 | 0.5201 |
Brugia malayi | Cathepsin L-like precursor | 0.2053 | 0.5201 | 0.5201 |
Onchocerca volvulus | 0.2053 | 0.5201 | 1 | |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0647 | 0.0622 | 0.0622 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.2053 | 0.5201 | 0.5201 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1104 | 0.2108 | 0.2108 |
Echinococcus multilocularis | cysteine protease | 0.2053 | 0.5201 | 0.5201 |
Onchocerca volvulus | 0.2053 | 0.5201 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1406 | 0.3093 | 0.3183 |
Brugia malayi | Cathepsin L-like precursor | 0.2053 | 0.5201 | 0.5201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.1406 | 0.3093 | 0.3093 |
Toxoplasma gondii | cathepsin B | 0.1406 | 0.3093 | 0.5947 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Echinococcus granulosus | cathepsin b | 0.3526 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.2053 | 0.5201 | 0.5201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3526 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2053 | 0.5201 | 0.5201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3526 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.2053 | 0.5201 | 0.5201 |
Echinococcus granulosus | cathepsin l1 | 0.1406 | 0.3092 | 0.3092 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Onchocerca volvulus | 0.2053 | 0.5201 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2053 | 0.5201 | 0.5201 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1104 | 0.2108 | 0.2108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Plasmodium vivax | unspecified product | 0.0647 | 0.0622 | 0.1196 |
Echinococcus multilocularis | cathepsin L | 0.1104 | 0.2108 | 0.2108 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2053 | 0.5201 | 0.5201 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2053 | 0.5201 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.2053 | 0.5201 | 1 |
Plasmodium vivax | vivapain-1 | 0.1104 | 0.2108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1406 | 0.3092 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.2053 | 0.5201 | 0.5201 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1406 | 0.3092 | 0.3092 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1104 | 0.2108 | 0.4054 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.1104 | 0.2108 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1406 | 0.3092 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1406 | 0.3092 | 0.3092 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2053 | 0.5201 | 0.5201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2053 | 0.5201 | 0.5201 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1104 | 0.2108 | 0.2108 |
Brugia malayi | Cathepsin L-like precursor | 0.0647 | 0.0622 | 0.0622 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2053 | 0.5201 | 0.5201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Plasmodium vivax | vivapain-2 | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0526 | 0.0228 | 0.0438 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.2053 | 0.5201 | 0.5201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1104 | 0.2108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1406 | 0.3092 | 0.3092 |
Brugia malayi | Papain family cysteine protease containing protein | 0.2053 | 0.5201 | 0.5201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2053 | 0.5201 | 0.5201 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0563 | 0.0348 | 0.0348 |
Loa Loa (eye worm) | hypothetical protein | 0.1406 | 0.3092 | 0.3092 |
Echinococcus granulosus | cysteine protease | 0.1104 | 0.2108 | 0.2108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.1406 | 0.3092 | 0.3092 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3526 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.3526 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3526 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3526 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.2053 | 0.5201 | 0.5201 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0647 | 0.0622 | 0.0622 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Loa Loa (eye worm) | fibroinase | 0.2053 | 0.5201 | 0.5201 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1104 | 0.2108 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.1406 | 0.3092 | 0.3092 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.2053 | 0.5201 | 0.5201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1406 | 0.3092 | 0.3092 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2053 | 0.5201 | 0.5201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.1104 | 0.2108 | 0.2108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1104 | 0.2108 | 0.2108 |
Brugia malayi | Cathepsin L-like precursor | 0.1406 | 0.3092 | 0.3092 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1104 | 0.2108 | 0.2108 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.2053 | 0.5201 | 0.5201 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0647 | 0.0622 | 0.0622 |
Echinococcus granulosus | cathepsin l1 | 0.2053 | 0.5201 | 0.5201 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.1104 | 0.2108 | 0.2108 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Onchocerca volvulus | 0.2053 | 0.5201 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2053 | 0.5201 | 0.5201 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0526 | 0.0228 | 0.0438 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1406 | 0.3093 | 0.3093 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0615 | 0.0517 | 0.0517 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0563 | 0.0348 | 0.0348 |
Loa Loa (eye worm) | hypothetical protein | 0.0647 | 0.0622 | 0.0622 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Onchocerca volvulus | 0.2053 | 0.5201 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1104 | 0.2108 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.1406 | 0.3093 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 0.0106 | 0.0106 |
Echinococcus multilocularis | cathepsin b | 0.3526 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1406 | 0.3093 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1104 | 0.2108 | 0.2108 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1104 | 0.2108 | 0.2108 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2053 | 0.5201 | 0.5201 |
Loa Loa (eye worm) | hypothetical protein | 0.0647 | 0.0622 | 0.0622 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1406 | 0.3092 | 0.5946 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.2053 | 0.5201 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.2053 | 0.5201 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1406 | 0.3093 | 0.3093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Onchocerca volvulus | 0.2053 | 0.5201 | 1 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0615 | 0.0517 | 0.0517 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Plasmodium vivax | unspecified product | 0.1104 | 0.2108 | 0.4054 |
Echinococcus multilocularis | cathepsin b | 0.3526 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.2053 | 0.5201 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.1104 | 0.2108 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1104 | 0.2108 | 0.4054 |
Onchocerca volvulus | 0.2053 | 0.5201 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.2053 | 0.5201 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1406 | 0.3092 | 0.3092 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.2053 | 0.5201 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.1104 | 0.2108 | 0.2108 |
Giardia lamblia | Cathepsin B precursor | 0.1406 | 0.3093 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0647 | 0.0622 | 0.0622 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2053 | 0.5201 | 0.5201 |
Toxoplasma gondii | cathepsin CPL | 0.2053 | 0.5201 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.2053 | 0.5201 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0647 | 0.0622 | 0.0622 |
Onchocerca volvulus | Cathepsin F homolog | 0.2053 | 0.5201 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.1104 | 0.2108 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3526 | 1 | 1 |
Onchocerca volvulus | 0.1406 | 0.3092 | 0.5946 | |
Entamoeba histolytica | cysteine protease, putative | 0.1104 | 0.2108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2053 | 0.5201 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0647 | 0.0622 | 0.0622 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.