Detailed information for compound 943852

Basic information

Technical information
  • TDR Targets ID: 943852
  • Name: 6-fluoro-3-methyl-2-(7-phenyl-1H-indol-3-yl)q uinoline-4-carboxylic acid
  • MW: 396.413 | Formula: C25H17FN2O2
  • H donors: 2 H acceptors: 3 LogP: 5.6 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc2c(c1)c(C(=O)O)c(c(n2)c1c[nH]c2c1cccc2c1ccccc1)C
  • InChi: 1S/C25H17FN2O2/c1-14-22(25(29)30)19-12-16(26)10-11-21(19)28-23(14)20-13-27-24-17(8-5-9-18(20)24)15-6-3-2-4-7-15/h2-13,27H,1H3,(H,29,30)
  • InChiKey: KPGFVGXICGWEBO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-fluoro-3-methyl-2-(7-phenyl-1H-indol-3-yl)-4-quinolinecarboxylic acid
  • 6-fluoro-3-methyl-2-(7-phenyl-1H-indol-3-yl)cinchoninic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0029 0.0067 0.0067
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0063 0.0063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0249 0.1479
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.0326 0.0326
Schistosoma mansoni histamine h1 receptor 0.0028 0.0063 0.0062
Echinococcus multilocularis sodium leak channel non selective protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0455 0.1654 0.1654
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus granulosus TRP transient receptor potential channel 0.0013 0.0005 0.0005
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0013 0.0005 0.0004
Echinococcus granulosus solute carrier family 22 0.0029 0.0066 0.0066
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0005 0.0005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0063 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0099 0.0736
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0196 0.1159
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0038 0.0038
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0099 0.043
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Echinococcus granulosus calcium activated potassium channel 0.0013 0.0007 0.0007
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0151 0.0151
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0038 0.0261
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0066 0.0476
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0029 0.0066 0.0369
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0099 0.0736
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi hypothetical protein 0.0029 0.0066 0.0065
Brugia malayi beta-lactamase 0.0038 0.0099 0.0099
Echinococcus granulosus acetylcholinesterase 0.2691 1 1
Echinococcus granulosus GPCR family 2 0.0047 0.0134 0.0134
Schistosoma mansoni inositol monophosphatase 0.0078 0.0249 0.0248
Brugia malayi hypothetical protein 0.0029 0.0066 0.0065
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0151 0.1143
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0455 0.1654 0.1654
Mycobacterium tuberculosis Conserved protein 0.0038 0.0099 0.043
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0099 0.0571
Echinococcus granulosus peregrin 0.003 0.007 0.007
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0063 0.0062
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0455 0.1654 0.1654
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0151 0.0151
Onchocerca volvulus 0.0028 0.0063 0.035
Echinococcus granulosus neuropeptide receptor A26 0.0028 0.0063 0.0063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0249 0.1479
Brugia malayi hypothetical protein 0.0017 0.0019 0.0019
Onchocerca volvulus 0.0028 0.0063 0.035
Brugia malayi jmjC domain containing protein 0.0099 0.0326 0.0325
Schistosoma mansoni amine GPCR 0.0028 0.0063 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni importin beta-1 0.0029 0.0067 0.0067
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0313 0.1127 0.1127
Trypanosoma cruzi hexose transporter, putative 0.0064 0.0196 0.1493
Echinococcus granulosus alpha 1A adrenergic receptor 0.0028 0.0063 0.0063
Schistosoma mansoni two-pore calcium channel 0.0013 0.0005 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0028 0.0063 0.035
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0099 0.0099
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0066 0.0065
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0013 0.0005 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Echinococcus multilocularis sodium channel protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0249 0.0249
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.0379
Echinococcus granulosus dnaJ subfamily B 0.0407 0.1477 0.1477
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0206 0.0726 0.0726
Schistosoma mansoni cpg binding protein 0.003 0.007 0.007
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0206 0.0726 0.0726
Echinococcus multilocularis voltage dependent calcium channel 0.0013 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0151 0.1143
Echinococcus multilocularis neuropeptide receptor A26 0.0028 0.0063 0.0063
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0066 0.0476
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0063 0.0063
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0183 0.0948
Echinococcus multilocularis neuropeptide s receptor 0.0028 0.0063 0.0063
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0066 0.0066
Echinococcus multilocularis G protein coupled receptor 139 0.0028 0.0063 0.0063
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.016 0.2148
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.2691 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0182 0.0636 0.0636
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.019 0.0189
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0038 0.0038
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.0861 0.5119
Echinococcus multilocularis voltage dependent calcium channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0005 0.0004
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.2691 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Onchocerca volvulus 0.0455 0.1654 1
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Echinococcus multilocularis acetylcholinesterase 0.2691 1 1
Schistosoma mansoni hypothetical protein 0.0313 0.1127 0.1126
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0151 0.0887
Loa Loa (eye worm) voltage-gated calcium channel 0.0013 0.0005 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0005 0.0005
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0455 0.1654 0.1654
Echinococcus granulosus hypothetical protein 0.0695 0.2551 0.2551
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0038 0.0751
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0151 0.1143
Onchocerca volvulus 0.0028 0.0063 0.035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0046 0.0252
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0164 0.0571 0.057
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0013 0.0005 0.0005
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0029 0.0029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0184 0.0183
Echinococcus multilocularis neuropeptides capa receptor 0.0028 0.0063 0.0063
Echinococcus granulosus neuropeptide receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis solute carrier family 22 0.0029 0.0066 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0063 0.0063
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0206 0.0726 0.0726
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0005 0.0004
Onchocerca volvulus 0.0029 0.0066 0.0369
Schistosoma mansoni hypothetical protein 0.0407 0.1477 0.1477
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0028 0.0063 0.035
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.007 0.0069
Echinococcus granulosus ryanodine receptor 44f 0.0013 0.0005 0.0005
Echinococcus multilocularis General substrate transporter 0.0177 0.0618 0.0618
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis serotonin receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0099 0.0571
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Echinococcus multilocularis conserved hypothetical protein 0.0013 0.0005 0.0005
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0005 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0134
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.0196 0.1493
Schistosoma mansoni glucose transport protein 0.0206 0.0726 0.0726
Echinococcus granulosus General substrate transporter 0.0177 0.0618 0.0618
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0013 0.0005 0.0004
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0094 0.0094
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0455 0.1654 1
Brugia malayi ion channel NompC 0.0013 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0356 0.1285 0.1285
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0005 0.0004
Brugia malayi beta-lactamase family protein 0.0038 0.0099 0.0099
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0206 0.0726 0.0726
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Echinococcus granulosus dro:myosuppressin receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0005 0.0005
Schistosoma mansoni biogenic amine receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0099
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0206 0.0726 0.0726
Brugia malayi hypothetical protein 0.0029 0.0066 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0066 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0066 0.0065
Brugia malayi CXXC zinc finger family protein 0.0029 0.0064 0.0064
Plasmodium vivax sugar transporter, putative 0.0029 0.0066 0.0894
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0249 0.0249
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0063 0.0062
Schistosoma mansoni opsin-like receptor 0.0028 0.0063 0.0062
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0013 0.0005 0.0005
Onchocerca volvulus 0.0028 0.0063 0.035
Onchocerca volvulus 0.0028 0.0063 0.035
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0099 0.0099
Onchocerca volvulus 0.0455 0.1654 1
Echinococcus granulosus hypothetical protein 0.0013 0.0005 0.0005
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0028 0.0063 0.0063
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0005 0.0005
Brugia malayi Importin beta-1 subunit 0.0029 0.0067 0.0067
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0038 0.0099 0.0571
Echinococcus multilocularis short transient receptor potential channel 6 0.0013 0.0005 0.0005
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0249 0.1479
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0455 0.1654 0.1654
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0134 0.0134
Echinococcus multilocularis sex peptide receptor 0.0028 0.0063 0.0063
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0099 0.0098
Brugia malayi Dopamine receptor protein 1 0.0028 0.0063 0.0062
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Loa Loa (eye worm) voltage-gated potassium channel 0.0013 0.0005 0.0004
Trypanosoma brucei glucose transporter 1E 0.0064 0.0196 0.1493
Echinococcus granulosus short transient receptor potential channel 6 0.0013 0.0005 0.0005
Schistosoma mansoni neuropeptide receptor 0.0028 0.0063 0.0062
Toxoplasma gondii facilitative glucose transporter GT1 0.0206 0.0726 1
Onchocerca volvulus 0.0029 0.0066 0.0369
Brugia malayi MAP kinase sur-1 0.0052 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0028 0.0063 0.035
Mycobacterium ulcerans ion transport protein 0.03 0.1077 0.6445
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0005 0.0005
Brugia malayi G protein-coupled receptor F59B2.13 0.0028 0.0063 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0114 0.0114
Onchocerca volvulus 0.0028 0.0063 0.035
Echinococcus granulosus acetylcholinesterase 0.2691 1 1
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.007 0.0903
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0063 0.0062
Echinococcus granulosus short transient receptor potential channel 6 0.0013 0.0005 0.0005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0028 0.0063 0.0062
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0455 0.1654 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0064 0.0196 0.1493
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0183 0.2473
Echinococcus granulosus solute carrier family 22 0.0029 0.0066 0.0066
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0134 0.0134
Brugia malayi RE15519p 0.0028 0.0063 0.0062
Echinococcus multilocularis geminin 0.0164 0.0571 0.0571
Echinococcus multilocularis conserved hypothetical protein 0.0667 0.2446 0.2446
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0028 0.0063 0.0062
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0063 0.0063
Trypanosoma cruzi hexose transporter, putative 0.0064 0.0196 0.1493
Echinococcus multilocularis somatostatin receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis solute carrier family 22 0.0029 0.0066 0.0066
Plasmodium falciparum hexose transporter 0.0206 0.0726 1
Schistosoma mansoni sugar transporter 0.0029 0.0066 0.0065
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.007 0.007
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0005 0.0005
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0114 0.0114
Loa Loa (eye worm) beta-lactamase 0.0038 0.0099 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Brugia malayi Serotonin receptor 0.0028 0.0063 0.0062
Schistosoma mansoni 60S ribosomal protein L21 0.0013 0.0005 0.0004
Schistosoma mansoni neuroligin 3 (S09 family) 0.0455 0.1654 0.1654
Trypanosoma brucei protein kinase, putative 0.0052 0.0151 0.1143
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Schistosoma mansoni amine GPCR 0.0028 0.0063 0.0062
Brugia malayi cation channel family protein 0.0013 0.0005 0.0004
Echinococcus granulosus two pore calcium channel protein 1 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0013 0.0005 0.0004
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0066 0.0894
Echinococcus granulosus 7TM GPCR rhodopsin 0.0028 0.0063 0.0063
Leishmania major importin beta-1 subunit, putative 0.0024 0.0046 0.0325
Schistosoma mansoni jumonji domain containing protein 0.0078 0.025 0.0249
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Echinococcus multilocularis dro:myosuppressin receptor 0.0028 0.0063 0.0063
Brugia malayi major facilitator superfamily protein 0.0029 0.0066 0.0065
Toxoplasma gondii sugar transporter ST2 0.0029 0.0066 0.0844
Onchocerca volvulus 0.0455 0.1654 1
Onchocerca volvulus 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0067 0.0487
Onchocerca volvulus 0.0028 0.0063 0.035
Echinococcus multilocularis snurportin 1 0.0313 0.1127 0.1127
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0206 0.0726 0.0726
Echinococcus multilocularis calcium activated potassium channel 0.0013 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0066 0.0066
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0053 0.0673
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0134 0.0134
Brugia malayi Inositol-1 0.0078 0.0249 0.0248
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.0196 0.1493
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Schistosoma mansoni opsin-like receptor 0.0028 0.0063 0.0062
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0134 0.0134
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0013 0.0005 0.0005
Echinococcus granulosus g protein coupled receptor 0.0028 0.0063 0.0063
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.1477 0.1477
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0099 0.1353
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0013 0.0005 0.0005
Onchocerca volvulus 0.0029 0.0064 0.0361
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Schistosoma mansoni voltage-gated cation channel 0.0013 0.0005 0.0004
Echinococcus granulosus para nitrobenzyl esterase 0.0455 0.1654 0.1654
Loa Loa (eye worm) G-protein coupled receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.2691 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0005 0.0005
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0038 0.0038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0028 0.0063 0.0062
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0005 0.0004
Brugia malayi Serotonin receptor 0.0473 0.1721 0.1721
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0183 0.0183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0029 0.0189
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0066 0.0369
Echinococcus granulosus sex peptide receptor 0.0028 0.0063 0.0063
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0455 0.1654 0.1654
Trypanosoma brucei glucose transporter 2A 0.0064 0.0196 0.1493
Schistosoma mansoni transient receptor potential channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Brugia malayi beta-lactamase family protein 0.0038 0.0099 0.0099
Trypanosoma brucei C-8 sterol isomerase, putative 0.0356 0.1285 1
Onchocerca volvulus 0.0028 0.0063 0.035
Loa Loa (eye worm) calcium channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) TYRA-2 protein 0.0028 0.0063 0.0062
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0013 0.0005 0.0005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0515 0.0515
Schistosoma mansoni opsin-like receptor 0.0028 0.0063 0.0062
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0067 0.0487
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.01 0.0099
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0013 0.0005 0.0004
Brugia malayi Dopamine receptor protein 2 0.0028 0.0063 0.0062
Loa Loa (eye worm) ryanodine receptor 0.0013 0.0005 0.0004
Echinococcus multilocularis solute carrier family 22 0.0029 0.0066 0.0066
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0099 0.043
Schistosoma mansoni neuropeptide receptor 0.0028 0.0063 0.0062
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0206 0.0726 0.0726
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0053 0.0379
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0066 0.0844
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0029 0.0147
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0029 0.0147
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0005 0.0004
Mycobacterium tuberculosis Conserved protein 0.0038 0.0099 0.043
Schistosoma mansoni growth hormone secretagogue receptor 0.0028 0.0063 0.0062
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0099 0.0736
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0724
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0028 0.0063 0.0062
Schistosoma mansoni cpg binding protein 0.0029 0.0064 0.0064
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0028 0.0063 0.0062
Brugia malayi putative neuropeptide receptor NPR1 0.0028 0.0063 0.0062
Echinococcus granulosus voltage dependent calcium channel 0.0013 0.0005 0.0005
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0099 0.0571
Loa Loa (eye worm) ion channel NompC 0.0013 0.0005 0.0004
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0249 0.1352
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.01 0.0099
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0515 0.0515
Schistosoma mansoni amine GPCR 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Echinococcus granulosus serotonin receptor 0.0028 0.0063 0.0063
Onchocerca volvulus Alhambra homolog 0.003 0.007 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0206 0.0726 0.4374
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0029 0.0389
Schistosoma mansoni hypothetical protein 0.0013 0.0005 0.0004
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0249 0.3381
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0053 0.0724
Echinococcus multilocularis short transient receptor potential channel 6 0.0013 0.0005 0.0005
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0249 0.1905
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0206 0.0726 0.0726
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Plasmodium falciparum importin beta, putative 0.0029 0.0067 0.0914
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi G-protein coupled receptor 0.0028 0.0063 0.0062
Schistosoma mansoni BC026374 protein (S09 family) 0.0455 0.1654 0.1654
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0151 0.2029
Schistosoma mansoni voltage-gated ion channel 0.0013 0.0005 0.0004
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0066 0.0066
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0013 0.0005 0.0004
Brugia malayi hypothetical protein 0.0013 0.0005 0.0004
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) voltage-gated potassium channel 0.0013 0.0005 0.0004
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0356 0.1285 0.1285
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0066 0.0225
Onchocerca volvulus 0.0028 0.0063 0.035
Loa Loa (eye worm) acetylcholinesterase 1 0.2691 1 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0005 0.0005
Echinococcus multilocularis GPCR, family 2 0.0047 0.0134 0.0134
Echinococcus multilocularis serotonin receptor 0.0028 0.0063 0.0063
Brugia malayi putative neuropeptide receptor 0.0028 0.0063 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0029 0.0389
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0151 0.0151
Echinococcus multilocularis peregrin 0.003 0.007 0.007
Echinococcus granulosus neuropeptide FF receptor 2 0.0028 0.0063 0.0063
Schistosoma mansoni ran 0.0022 0.0038 0.0038
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0063 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus granulosus shaker cognate 0.0013 0.0005 0.0005
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0066 0.0476
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0038 0.0515
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0013 0.0005 0.0005
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0029 0.0189
Onchocerca volvulus 0.0029 0.0066 0.0369
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0005 0.0004
Echinococcus granulosus g protein coupled receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0028 0.0063 0.035
Brugia malayi Cyclic-nucleotide gated cation channel 0.0013 0.0005 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0029 0.0066 0.0369
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0013 0.0005 0.0004
Echinococcus granulosus voltage gated hydrogen channel 1 0.0013 0.0005 0.0005
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0066 0.0369
Brugia malayi cation channel family protein 0.0013 0.0005 0.0004
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0099
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0046 0.0252
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Giardia lamblia Hexose transporter 0.0029 0.0066 0.3001
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0063 0.0063
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0005 0.0005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0134 0.0134
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0013 0.0005 0.0005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0455 0.1654 0.1654
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0249 0.1905
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0063 0.0063
Onchocerca volvulus 0.0028 0.0063 0.035
Onchocerca volvulus 0.0029 0.0066 0.0369
Brugia malayi Sugar transporter family protein 0.0029 0.0066 0.0065
Echinococcus granulosus snurportin 1 0.0313 0.1127 0.1127
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Leishmania major GTP-binding protein, putative 0.0022 0.0038 0.0261
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0067 0.0864
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0066 0.0225
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0028 0.0063 0.035
Schistosoma mansoni amine GPCR 0.0028 0.0063 0.0062
Echinococcus multilocularis neuropeptide FF receptor 2 0.0028 0.0063 0.0063
Schistosoma mansoni sugar transporter 0.0029 0.0066 0.0065
Schistosoma mansoni hypothetical protein 0.0047 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0206 0.0726 0.0726
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0013 0.0005 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0063 0.0063
Brugia malayi Carboxylesterase family protein 0.2691 1 1
Echinococcus granulosus neuropeptide receptor 0.0028 0.0063 0.0063
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0063 0.0063
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0455 0.1654 1
Onchocerca volvulus 0.0029 0.0066 0.0369
Leishmania major C-8 sterol isomerase-like protein 0.0356 0.1285 1
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0005 0.0005
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0005 0.0005
Echinococcus granulosus G protein coupled receptor 139 0.0028 0.0063 0.0063
Schistosoma mansoni glucose transporter 0.0029 0.0066 0.0065
Loa Loa (eye worm) sugar transporter 0.0206 0.0726 0.0726
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0005 0.0005
Brugia malayi olfactory channel protein osm-9 0.0013 0.0005 0.0004
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0455 0.1654 0.1654
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Loa Loa (eye worm) sugar transporter 0.0029 0.0066 0.0065
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0028 0.0063 0.0062
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0063 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Brugia malayi neuropeptide F receptor 0.0028 0.0063 0.0062
Schistosoma mansoni hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi Carboxylesterase family protein 0.0455 0.1654 0.1654
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0151 0.0887
Schistosoma mansoni ap endonuclease 0.0019 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Entamoeba histolytica hypothetical protein 0.0024 0.0046 0.0791
Echinococcus multilocularis allatostatin A receptor 0.0028 0.0063 0.0063
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0218 0.1164
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0028 0.0063 0.0062
Giardia lamblia PHD finger protein 15 0.003 0.007 0.335
Echinococcus granulosus transient receptor potential gamma protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0029 0.0189
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0099 0.0099
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0102 0.0339 0.0338
Leishmania major glucose transporter, lmgt3 0.0064 0.0196 0.1493
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0028 0.0063 0.0063
Echinococcus granulosus neuroligin 0.0455 0.1654 0.1654
Brugia malayi follicle stimulating hormone receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus granulosus sodium leak channel non selective protein 0.0013 0.0005 0.0005
Schistosoma mansoni neuropeptide receptor 0.0028 0.0063 0.0062
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0013 0.0005 0.0004
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0099 0.043
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0028 0.0063 0.0062
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0151 0.1143
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0029 0.0066 0.0369
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0028 0.0063 0.0062
Echinococcus granulosus sodium channel protein 0.0013 0.0005 0.0005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0066 0.0369
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0029 0.0029
Echinococcus granulosus two pore calcium channel protein 2 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0099 0.043
Leishmania major hypothetical protein, conserved 0.0029 0.0066 0.0476
Loa Loa (eye worm) voltage-gated potassium channel 0.0399 0.1448 0.1448
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0013 0.0005 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0066 0.0065
Schistosoma mansoni glucose transport protein 0.0206 0.0726 0.0726
Echinococcus multilocularis cpg binding protein 0.003 0.007 0.007
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0066 0.0065
Brugia malayi Carboxylesterase family protein 0.0455 0.1654 0.1654
Onchocerca volvulus 0.0455 0.1654 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0249 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.0326 0.0326
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0099 0.0098
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0066 0.0066
Schistosoma mansoni calcium-activated potassium channel 0.0013 0.0005 0.0004
Onchocerca volvulus 0.0455 0.1654 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0013 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0249 0.1905
Echinococcus granulosus tachykinin peptides receptor 99D 0.0028 0.0063 0.0063
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0063 0.0063
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0249 1
Loa Loa (eye worm) PHD-finger family protein 0.003 0.007 0.007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0183 0.1393
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0151 0.0151
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0151 0.0151
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0005 0.0005
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0151 0.1143
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0038 0.0261
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0356 0.1285 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0218 1
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0063 0.0062
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.0379
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0013 0.0005 0.0005
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0028 0.0063 0.0062
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0151 1
Echinococcus multilocularis BC026374 protein (S09 family) 0.0455 0.1654 0.1654
Schistosoma mansoni neuropeptide f receptor 76f 0.0028 0.0063 0.0062
Echinococcus granulosus neuropeptides capa receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0013 0.0005 0.0005
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0099 0.043
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Echinococcus multilocularis transfer RNA-Gly 0.0013 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Entamoeba histolytica Ran family GTPase 0.0022 0.0038 0.0418
Echinococcus multilocularis ryanodine receptor 44f 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0099
Trypanosoma cruzi hexose transporter, putative 0.0064 0.0196 0.1493
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0013 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0047 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0066 0.0065
Giardia lamblia Sugar-proton symporter 0.0029 0.0066 0.3001
Schistosoma mansoni transient receptor potential channel 4 0.0013 0.0005 0.0004
Schistosoma mansoni vesicular amine transporter 0.0013 0.0005 0.0004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus granulosus cpg binding protein 0.003 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Plasmodium vivax hexose transporter 0.0206 0.0726 1
Brugia malayi RNA, U transporter 1 0.0083 0.0269 0.0269
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0005 0.0005
Echinococcus granulosus voltage dependent calcium channel 0.0013 0.0005 0.0005
Echinococcus multilocularis shaker cognate 0.0013 0.0005 0.0005
Trichomonas vaginalis glucose transporter, putative 0.0064 0.0196 0.1159
Toxoplasma gondii ABC1 family protein 0.0038 0.0099 0.1306
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0029 0.0029
Trypanosoma brucei THT1 - hexose transporter, putative 0.0064 0.0196 0.1493
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0027 0.0027
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0151 0.0887
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0038 0.0261
Echinococcus multilocularis g-protein coupled receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0063 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0183 0.0948
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0028 0.0063 0.0063
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0183 0.0183
Echinococcus granulosus peptide allatostatin:somatostatin 0.0028 0.0063 0.0063
Brugia malayi Dopamine receptor 0.0028 0.0063 0.0062
Schistosoma mansoni sugar transporter 0.0029 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0099 0.043
Mycobacterium ulcerans carboxylesterase, LipT 0.0455 0.1654 1
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0196 0.1159
Mycobacterium tuberculosis Carboxylesterase LipT 0.0455 0.1654 1
Onchocerca volvulus 0.0038 0.0099 0.0571
Schistosoma mansoni sugar transporter 0.0029 0.0066 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0066 0.0369
Schistosoma mansoni transient receptor potential channel 0.0013 0.0005 0.0004
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0005 0.0005
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0099 0.043
Echinococcus multilocularis g protein coupled receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis potassium large conductance calcium activated 0.0013 0.0005 0.0005
Onchocerca volvulus 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0149 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi larval opioid receptor 0.0028 0.0063 0.0062
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Echinococcus granulosus carboxylesterase 5A 0.2691 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0066 0.0369
Echinococcus granulosus g-protein coupled receptor 0.0028 0.0063 0.0063
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0046 0.0325
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0038 0.0038
Brugia malayi Bromodomain containing protein 0.003 0.007 0.007
Echinococcus granulosus somatostatin receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis neuroligin 0.0455 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0029 0.5
Toxoplasma gondii sugar transporter ST3 0.0029 0.0066 0.0844
Brugia malayi Carboxylesterase family protein 0.0455 0.1654 0.1654
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus granulosus orexin receptor type 2 0.0028 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.003 0.007 0.007
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus granulosus tm gpcr rhodopsin 0.0028 0.0063 0.0063
Onchocerca volvulus 0.0028 0.0063 0.035
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0183 0.0183
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0028 0.0063 0.0063
Echinococcus granulosus solute carrier family 22 0.0029 0.0066 0.0066
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0046 0.0252
Loa Loa (eye worm) carboxylesterase 0.0455 0.1654 0.1654
Toxoplasma gondii exonuclease III APE 0.0019 0.0029 0.0336
Mycobacterium ulcerans sugar transporter 0.0029 0.0066 0.0225
Schistosoma mansoni alpha-1 adrenergic receptor 0.0028 0.0063 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0028 0.0063 0.0063
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0724
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0029 0.0189
Leishmania major hypothetical protein, conserved 0.0038 0.0099 0.0736
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0005 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0028 0.0063 0.0063
Echinococcus multilocularis acetylcholinesterase 0.2691 1 1
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0412 0.1496 0.1495
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Brugia malayi Carboxylesterase family protein 0.0455 0.1654 0.1654
Schistosoma mansoni voltage-dependent calcium channel 0.0013 0.0005 0.0004
Echinococcus multilocularis neuropeptide receptor 0.0028 0.0063 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis G-protein coupled receptor, putative 0.0028 0.0063 0.0063
Schistosoma mansoni acetylcholinesterase 0.0455 0.1654 0.1654
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Onchocerca volvulus 0.0028 0.0063 0.035
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0013 0.0005 0.0004
Onchocerca volvulus 0.0029 0.0066 0.0369
Schistosoma mansoni hypothetical protein 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0151 0.0151
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0005 0.0005
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Schistosoma mansoni myosin xvIII 0.0028 0.0063 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Leishmania major glucose transporter, lmgt2 0.0064 0.0196 0.1493
Onchocerca volvulus 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Onchocerca volvulus 0.0038 0.0099 0.0571
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) melatonin receptor type 1A 0.0028 0.0063 0.0062
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0028 0.0063 0.0063
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0005 0.0005
Echinococcus multilocularis solute carrier family 22 0.0029 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0183 0.0948
Schistosoma mansoni ap endonuclease 0.0019 0.0029 0.0028
Echinococcus granulosus fmrfamide receptor 0.0028 0.0063 0.0063
Echinococcus granulosus g protein coupled receptor 0.0028 0.0063 0.0063
Brugia malayi major facilitator superfamily protein 0.0029 0.0066 0.0065
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Brugia malayi hypothetical protein 0.0026 0.0053 0.0053
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0038 0.0463
Loa Loa (eye worm) neuropeptide F receptor 0.0028 0.0063 0.0062
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0013 0.0005 0.0004
Plasmodium vivax hypothetical protein, conserved 0.003 0.007 0.0953
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni inositol monophosphatase 0.0078 0.0249 0.0248
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0013 0.0005 0.0005
Echinococcus multilocularis para nitrobenzyl esterase 0.0455 0.1654 0.1654
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0099 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Trichomonas vaginalis esterase, putative 0.0038 0.0099 0.0571
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0013 0.0005 0.0004
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0013 0.0005 0.0004
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) inositol-1 0.0078 0.0249 0.0248
Schistosoma mansoni hypothetical protein 0.0164 0.0571 0.057
Mycobacterium ulcerans lipase LipD 0.0038 0.0099 0.043
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Onchocerca volvulus 0.0029 0.0066 0.0369
Schistosoma mansoni ran 0.0022 0.0038 0.0038
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Echinococcus granulosus solute carrier family 22 0.0029 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0005 0.0004
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Brugia malayi Melatonin receptor type 1A 0.0028 0.0063 0.0062
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0013 0.0005 0.0005
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0066 0.0225
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0099 0.043
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0013 0.0005 0.0005
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0028 0.0063 0.0062
Leishmania major glucose transporter, lmgt1 0.0064 0.0196 0.1493
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Brugia malayi GnHR receptor homolog 0.0028 0.0063 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.01 0.0099
Echinococcus multilocularis carboxylesterase 5A 0.2691 1 1
Schistosoma mansoni biogenic amine receptor 0.0028 0.0063 0.0062
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0134 0.0134
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0196 0.1159
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0455 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0028 0.0063 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Schistosoma mansoni ryanodine receptor related 0.0013 0.0005 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0249 0.1905
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0005 0.0005
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0088 0.0649
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0412 0.1496 0.1496
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0038 0.0515
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Brugia malayi AKH receptor 0.0028 0.0063 0.0062
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0028 0.0063 0.0063
Schistosoma mansoni cpg binding protein 0.003 0.007 0.007
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0028 0.0063 0.0063
Plasmodium falciparum phd finger protein, putative 0.003 0.007 0.0953
Schistosoma mansoni adenoreceptor 0.0028 0.0063 0.0062
Schistosoma mansoni hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi sulfakinin receptor protein 0.0028 0.0063 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Brugia malayi neuropeptide F receptor 0.0028 0.0063 0.0062
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0021 0.002
Leishmania major hypothetical protein, conserved 0.0026 0.0053 0.0379
Trichomonas vaginalis ran, putative 0.0022 0.0038 0.0203
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0066 0.0225
Brugia malayi hypothetical protein 0.0455 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0102 0.0339 0.0338
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0066 0.0065
Onchocerca volvulus 0.0028 0.0063 0.035
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0455 0.1654 0.1654
Schistosoma mansoni hypothetical protein 0.0047 0.0134 0.0134
Onchocerca volvulus Neuropeptide F receptor homolog 0.0028 0.0063 0.035
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0066 0.0225
Echinococcus granulosus neuropeptide s receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Trichomonas vaginalis spcc417.12 protein, putative 0.0455 0.1654 1
Echinococcus granulosus neuropeptide Y receptor 0.0028 0.0063 0.0063
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Brugia malayi ORL1-like opioid receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0183 0.0948
Brugia malayi PHD-finger family protein 0.003 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0066 0.0065
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0028 0.0063 0.0062
Echinococcus granulosus potassium voltage gated channel protein 0.0013 0.0005 0.0005
Echinococcus granulosus potassium large conductance calcium activated 0.0013 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.0455 0.1654 0.1654
Schistosoma mansoni biogenic amine receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.015
Echinococcus multilocularis transient receptor potential gamma protein 0.0013 0.0005 0.0005
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0013 0.0005 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0151 0.0887
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0005 0.0005
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0028 0.0063 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0196 0.1159
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0013 0.0005 0.0005
Onchocerca volvulus 0.0029 0.0066 0.0369
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0515 0.0515
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0005 0.0005
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) voltage-dependent calcium channel 0.0013 0.0005 0.0004
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Schistosoma mansoni amine GPCR 0.0028 0.0063 0.0062
Plasmodium vivax importin-beta 2, putative 0.0029 0.0067 0.0914
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0099 0.043
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Echinococcus granulosus allatostatin A receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0064 0.0064
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0412 0.1496 0.1496
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0005 0.0004
Echinococcus multilocularis neuropeptide Y receptor 0.0028 0.0063 0.0063
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0013 0.0005 0.0004
Echinococcus multilocularis fmrfamide receptor 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Mycobacterium tuberculosis Conserved protein 0.0038 0.0099 0.043
Echinococcus granulosus transient receptor potential cation channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0099
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0005 0.0004
Echinococcus granulosus geminin 0.0164 0.0571 0.0571
Schistosoma mansoni glucose transport protein 0.0206 0.0726 0.0726
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0099 0.0571
Echinococcus multilocularis two pore calcium channel protein 2 0.0013 0.0005 0.0005
Schistosoma mansoni gliotactin 0.0455 0.1654 0.1654
Toxoplasma gondii sugar transporter ST1 0.0029 0.0066 0.0844
Brugia malayi G-protein coupled receptor 0.0028 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0455 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.007 0.0903
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0005 0.0005
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Echinococcus multilocularis potassium voltage gated channel protein 0.0013 0.0005 0.0005
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0066 0.0476
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Brugia malayi Sugar transporter family protein 0.0206 0.0726 0.0726
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0028 0.0063 0.0063
Brugia malayi Sugar transporter family protein 0.0029 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.2691 1 1
Echinococcus multilocularis orexin receptor type 2 0.0028 0.0063 0.0063
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Echinococcus granulosus importin subunit beta 1 0.0029 0.0067 0.0067
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0013 0.0005 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0196 0.1159
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0066 0.0476
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0151 0.1143
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis two pore calcium channel protein 1 0.0013 0.0005 0.0005
Mycobacterium ulcerans beta-lactamase 0.0038 0.0099 0.043
Echinococcus granulosus BC026374 protein S09 family 0.0455 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Trypanosoma brucei sugar transporter, putative 0.0029 0.0066 0.0476
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0067 0.0067
Mycobacterium ulcerans hypothetical protein 0.0038 0.0099 0.043
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Brugia malayi jmjC domain containing protein 0.0038 0.01 0.0099
Trypanosoma brucei glucose transporter, putative 0.0064 0.0196 0.1493
Schistosoma mansoni hypothetical protein 0.003 0.007 0.0069
Onchocerca volvulus Putative transporter 0.0029 0.0066 0.0369
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0786 0.2891 0.2891
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Trichomonas vaginalis glucose transporter, putative 0.0064 0.0196 0.1159
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Onchocerca volvulus 0.0029 0.0066 0.0369
Echinococcus granulosus 7tm_1 domain containing protein 0.0028 0.0063 0.0063
Schistosoma mansoni neuropeptide receptor 0.0028 0.0063 0.0062
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0339 0.0338
Schistosoma mansoni transient receptor potential channel 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Loa Loa (eye worm) hypothetical protein 0.0455 0.1654 0.1654
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi hypothetical protein 0.0028 0.0063 0.0062
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0028 0.0063 0.0062
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0066 0.1668
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0013 0.0005 0.0005
Brugia malayi G protein-coupled receptor 0.0028 0.0063 0.0062
Brugia malayi Transient-receptor-potential like protein 0.0013 0.0005 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0099 0.0571
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0412 0.1496 0.1495
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0005 0.0004
Brugia malayi voltage-dependent calcium channel 0.0013 0.0005 0.0004
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0005 0.0005
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Schistosoma mansoni neuropeptide F-like receptor 0.0028 0.0063 0.0062
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0028 0.0063 0.0062
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0151 0.1143
Schistosoma mansoni hypothetical protein 0.0047 0.0134 0.0134
Trypanosoma cruzi hexose transporter 0.0064 0.0196 0.1493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0028 0.0063 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0066 0.0369
Echinococcus multilocularis transient receptor potential cation channel 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0099
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0013 0.0005 0.0004
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0013 0.0005 0.0005

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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