Detailed information for compound 945043

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 414.932 | Formula: C21H27ClN6O
  • H donors: 1 H acceptors: 4 LogP: 2.85 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC(n1c(nc2c1nc(C)nc2N1CCN(CC1)C)c1ccccc1Cl)(C)C
  • InChi: 1S/C21H27ClN6O/c1-14-23-19(27-11-9-26(4)10-12-27)17-20(24-14)28(21(2,3)13-29)18(25-17)15-7-5-6-8-16(15)22/h5-8,29H,9-13H2,1-4H3
  • InChiKey: BHSFBZWVKDKDEJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cannabinoid receptor 2 (macrophage) Starlite/ChEMBL References
Homo sapiens cannabinoid receptor 1 (brain) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus g protein coupled receptor 0.0045 0.0056 0.0056
Brugia malayi Protein kinase domain containing protein 0.0024 0.0021 0.0021
Plasmodium falciparum plasmepsin II 0.0019 0.0012 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) SH2 domain-containing protein 0.0015 0.0005 0.0005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0011 0.0011
Echinococcus multilocularis growth factor receptor bound protein 2 0.0019 0.0012 0.0012
Brugia malayi GnHR receptor homolog 0.0045 0.0056 0.0056
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0486 0.0801 0.0801
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0045 0.0056 0.0056
Echinococcus granulosus SHC transforming protein 3 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Loa Loa (eye worm) STAT protein 0.0015 0.0005 0.0005
Trypanosoma brucei C-8 sterol isomerase, putative 0.0761 0.1265 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0028 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus multilocularis NCK adaptor protein 0.0019 0.0012 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.002 0.002
Echinococcus granulosus defective proboscis extension response 0.0026 0.0025 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0403 0.0403
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0153
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0186 0.0294 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Brugia malayi Carboxylesterase family protein 0.1002 0.1673 0.1673
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Echinococcus multilocularis c src tyrosine kinase 0.0028 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0486 0.0801 0.0801
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Mycobacterium tuberculosis Carboxylesterase LipT 0.1002 0.1673 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0023 0.002 0.0239
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0028 0.0028 0.0028
Echinococcus granulosus SH2 motif 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi Sex muscle abnormal protein 5 0.0019 0.0012 0.0012
Entamoeba histolytica protein kinase domain containing protein 0.0442 0.0726 0.9929
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0088 0.0652
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0056 0.0056
Brugia malayi Dopamine receptor protein 1 0.0045 0.0056 0.0056
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0056 0.0056
Echinococcus granulosus sex peptide receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Echinococcus multilocularis SH2 motif 0.0015 0.0005 0.0005
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0027 0.0025 0.0025
Schistosoma mansoni gliotactin 0.1002 0.1673 0.1673
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0023 0.002 0.0121
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0023 0.002 0.002
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0023 0.002 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Trypanosoma cruzi carnitine O-palmitoyltransferase II, putative 0.0027 0.0025 0.0153
Echinococcus multilocularis Immunoglobulin 0.0026 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0045 0.0056 0.0307
Giardia lamblia Hypothetical protein 0.0023 0.002 0.0121
Echinococcus granulosus serine protein kinase ATM 0.0023 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.002 0.0052
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Onchocerca volvulus 0.0024 0.0021 0.0098
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0059 0.008 0.008
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0056 0.0056
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0023 0.002 0.0107
Plasmodium falciparum plasmepsin I 0.0019 0.0012 0.008
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0649 0.1076 0.6418
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0103 0.0154 0.2075
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0217 0.0217
Echinococcus granulosus tyrosine protein kinase shark 0.025 0.0402 0.0402
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0006 0.0002
Echinococcus granulosus Immunoglobulin 0.0026 0.0025 0.0025
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0056 0.0056
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0045 0.0056 0.0056
Brugia malayi Cytochrome P450 family protein 0.0015 0.0006 0.0006
Echinococcus granulosus protein kinase shaggy 0.0442 0.0726 0.0726
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0046 0.0057 0.0649
Brugia malayi putative neuropeptide receptor 0.0045 0.0056 0.0056
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.1002 0.1673 0.1673
Echinococcus multilocularis Immunoglobulin 0.0026 0.0025 0.0025
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0045 0.0056 0.0056
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.002 0.002
Echinococcus granulosus tyrosine protein kinase Src42A 0.0046 0.0057 0.0057
Echinococcus multilocularis tensin 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0048 0.0048
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0045 0.0056 0.0307
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.002 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0105 0.0157 0.0157
Echinococcus multilocularis serine protein kinase ATM 0.0023 0.002 0.002
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0045 0.0056 0.0056
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0045 0.0056 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0074 0.0376
Brugia malayi hypothetical protein 0.0019 0.0012 0.0012
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0024 0.0021 0.0021
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0015 0.0005 0.0005
Brugia malayi hypothetical protein 0.0026 0.0025 0.0025
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0442 0.0726 0.0726
Brugia malayi STAT protein, DNA binding domain containing protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.0057
Trypanosoma cruzi carnitine O-acetyltransferase, putative 0.0027 0.0025 0.0153
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.005 0.0605
Brugia malayi RhoGAP domain containing protein 0.0015 0.0005 0.0005
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0059 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0039 0.0046 0.0046
Brugia malayi aspartic protease BmAsp-2, identical 0.0019 0.0012 0.0012
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0019 0.0012 0.008
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0445 0.0732 0.5764
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0045 0.0056 0.0056
Plasmodium falciparum plasmepsin III 0.0019 0.0012 0.008
Schistosoma mansoni nck2/grb4 0.0019 0.0012 0.0012
Brugia malayi Carboxylesterase family protein 0.1002 0.1673 0.1673
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0011 0.0011
Schistosoma mansoni nephrin 0.0029 0.0029 0.0029
Echinococcus multilocularis acetylcholinesterase 0.5933 1 1
Echinococcus multilocularis somatostatin receptor 0.0045 0.0056 0.0056
Brugia malayi neuropeptide F receptor 0.0045 0.0056 0.0056
Echinococcus granulosus activin receptor type 0.0016 0.0006 0.0006
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0015 0.0005 0.0005
Echinococcus granulosus fmrfamide receptor 0.0045 0.0056 0.0056
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0023 0.002 0.002
Brugia malayi Choline O-acetyltransferase 0.0179 0.0283 0.0283
Loa Loa (eye worm) TK protein kinase 0.0041 0.0049 0.0049
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0045 0.0056 0.0056
Schistosoma mansoni opsin-like receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) TK protein kinase 0.0012 0.0001 0.0001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Echinococcus multilocularis carnitine O palmitoyltransferase 2 0.0027 0.0025 0.0025
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0442 0.0726 0.0726
Loa Loa (eye worm) phosphatidylinositol 3 0.0023 0.002 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Plasmodium vivax glycogen synthase kinase 3, putative 0.0442 0.0726 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0103 0.0154 0.0858
Trichomonas vaginalis CMGC family protein kinase 0.0442 0.0726 0.4304
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Plasmodium falciparum protoporphyrinogen oxidase 0.0046 0.0057 0.0708
Schistosoma mansoni neuropeptide receptor 0.0045 0.0056 0.0056
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0084 0.0084
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0023 0.002 0.0107
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0056 0.0056
Schistosoma mansoni growth factor receptor-bound protein 0.0019 0.0012 0.0012
Brugia malayi Serotonin receptor 0.0493 0.0812 0.0812
Entamoeba histolytica SH2 domain containing protein 0.0015 0.0005 0.0038
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0023 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0016 0.0006 0.0006
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0023 0.002 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0011 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0088 0.0088
Echinococcus granulosus tachykinin peptides receptor 99D 0.0045 0.0056 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Toxoplasma gondii aspartyl protease ASP1 0.0019 0.0012 0.008
Entamoeba histolytica protein kinase, putative 0.0442 0.0726 0.9929
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0442 0.0726 0.0726
Brugia malayi Tyrosine-protein kinase abl-1 0.0028 0.0028 0.0028
Loa Loa (eye worm) acetyltransferase 0.014 0.0217 0.0217
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0159 0.1215
Toxoplasma gondii FATC domain-containing protein 0.0023 0.002 0.0183
Loa Loa (eye worm) carboxylesterase 0.5933 1 1
Echinococcus granulosus neuropeptide receptor 0.0045 0.0056 0.0056
Schistosoma mansoni suppressor of cytokine signaling 0.0015 0.0005 0.0005
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0445 0.0732 1
Brugia malayi intracellular kinase 0.0442 0.0726 0.0726
Onchocerca volvulus 0.0046 0.0057 0.0314
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0011 0.5
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0128 0.0197 0.2666
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0084 0.0084
Echinococcus multilocularis neuropeptide receptor A26 0.0045 0.0056 0.0056
Plasmodium vivax plasmepsin V, putative 0.0019 0.0012 0.0017
Plasmodium vivax hypothetical protein 0.0023 0.002 0.0121
Echinococcus multilocularis neuroligin 0.1002 0.1673 0.1673
Plasmodium falciparum protein kinase 5 0.0051 0.0067 0.0838
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0088 0.0652
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0019 0.0012 0.0012
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1002 0.1673 0.1673
Plasmodium falciparum plasmepsin VII 0.0019 0.0012 0.008
Leishmania major carnitine palmitoyltransferase-like protein 0.0027 0.0025 0.0153
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0023 0.002 0.002
Brugia malayi Melatonin receptor type 1A 0.0045 0.0056 0.0056
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.038 0.0623 0.8547
Onchocerca volvulus 0.0045 0.0056 0.0307
Schistosoma mansoni tyrosine kinase 0.025 0.0402 0.0402
Onchocerca volvulus 0.0024 0.0021 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0159 0.0891
Trypanosoma cruzi cdc2-related kinase 1 0.0051 0.0067 0.0481
Loa Loa (eye worm) hypothetical protein 0.0062 0.0084 0.0084
Plasmodium falciparum plasmepsin X 0.0019 0.0012 0.008
Echinococcus multilocularis tyrosine protein kinase Srms 0.0055 0.0074 0.0074
Schistosoma mansoni amine GPCR 0.0045 0.0056 0.0056
Echinococcus granulosus c-Jun N-terminal kinases 0.025 0.0403 0.0403
Mycobacterium ulcerans monoamine oxidase 0.0046 0.0057 0.0307
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0103 0.0154 0.1172
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0023 0.002 0.0183
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0051 0.0067 0.0067
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0059 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0039
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0023 0.002 0.002
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0059 0.008 0.008
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0023 0.002 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0023 0.002 0.002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.1002 0.1673 1
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0056 0.0056
Schistosoma mansoni vesicular amine transporter 0.0029 0.0029 0.0029
Echinococcus granulosus N chimaerin 0.0015 0.0005 0.0005
Loa Loa (eye worm) TK/ABL protein kinase 0.0024 0.0021 0.0021
Trypanosoma cruzi target of rapamycin kinase 3 0.0023 0.002 0.0107
Echinococcus multilocularis roundabout 2 0.0032 0.0035 0.0035
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0023 0.002 0.0107
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0015 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0024 0.0021 0.0021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.002 0.002
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0023 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni BC026374 protein (S09 family) 0.1002 0.1673 0.1673
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.0027 0.0025 0.0025
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0045 0.0056 0.0056
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0048 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.0442 0.0726 0.4304
Loa Loa (eye worm) aspartyl protease 6 0.0019 0.0012 0.0012
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus granulosus acetylcholinesterase 0.5933 1 1
Mycobacterium ulcerans dehydrogenase 0.0046 0.0057 0.0307
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0015 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Schistosoma mansoni biogenic amine receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni growth factor receptor-bound protein 0.0019 0.0012 0.0012
Plasmodium vivax aspartyl protease, putative 0.0019 0.0012 0.0017
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0442 0.0726 0.5723
Brugia malayi Protein kinase domain containing protein 0.0051 0.0067 0.0067
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0442 0.0726 0.5723
Giardia lamblia GTOR 0.0023 0.002 0.0121
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0006 0.0006
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0046 0.0057 0.0649
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0103 0.0154 0.1172
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0019 0.0012 0.0012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0056 0.0056
Loa Loa (eye worm) acetylcholinesterase 1 0.5933 1 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0028 0.0028 0.0028
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0128 0.0197 0.0197
Echinococcus granulosus G protein coupled receptor 139 0.0045 0.0056 0.0056
Toxoplasma gondii histone lysine-specific demethylase 0.0046 0.0057 0.0708
Brugia malayi SH2 domain containing protein 0.0015 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0067 0.0067
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.1002 0.1673 0.1673
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0445 0.0732 0.4335
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0084 0.0084
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0023 0.002 0.0239
Echinococcus multilocularis BC026374 protein (S09 family) 0.1002 0.1673 0.1673
Entamoeba histolytica protein kinase, putative 0.0021 0.0015 0.0174
Loa Loa (eye worm) phosphatidylinositol 3 0.0023 0.002 0.002
Schistosoma mansoni tyrosine kinase 0.0015 0.0006 0.0006
Loa Loa (eye worm) TYRA-2 protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Toxoplasma gondii aspartyl protease ASP3 0.0019 0.0012 0.008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Brugia malayi tRNA modification GTPase TrmE family protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Echinococcus granulosus g-protein coupled receptor 0.0045 0.0056 0.0056
Brugia malayi hypothetical protein 0.0015 0.0005 0.0005
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0023 0.002 0.0107
Loa Loa (eye worm) phosphatidylinositol 3 0.0023 0.002 0.002
Schistosoma mansoni signal transduction protein lnk-related 0.0015 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0251 0.0251
Brugia malayi Pre-SET motif family protein 0.0429 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) SRC-1 0.0059 0.008 0.008
Leishmania major phosphatidylinositol 4-kinase, putative 0.0023 0.002 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Brugia malayi hypothetical protein 0.0046 0.0057 0.0057
Schistosoma mansoni amine GPCR 0.0045 0.0056 0.0056
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.0012 0.0012
Echinococcus granulosus tyrosine protein kinase Lyn 0.0065 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0103 0.0154 0.1172
Echinococcus multilocularis SH2 domain containing protein 7 0.0015 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Leishmania major protein kinase, putative 0.0016 0.0006 0.0002
Echinococcus granulosus growth factor receptor bound protein 2 0.0019 0.0012 0.0012
Echinococcus granulosus hypothetical protein 0.0716 0.119 0.119
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0084 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Onchocerca volvulus 0.0023 0.002 0.0088
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0056 0.0056
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0023 0.002 0.0239
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0019 0.0012 0.0012
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0012 0.0001 0.0001
Schistosoma mansoni choline o-acyltransferase 0.0027 0.0025 0.0025
Echinococcus granulosus neuropeptide receptor A26 0.0045 0.0056 0.0056
Trypanosoma cruzi UDP-galactopyranose mutase 0.0046 0.0057 0.0407
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0023 0.002 0.0107
Onchocerca volvulus 0.0045 0.0056 0.0307
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.005 0.0234
Echinococcus multilocularis sex peptide receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) phosphatidylinositol 3 0.0419 0.0689 0.0689
Schistosoma mansoni hypothetical protein 0.0164 0.0258 0.0258
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0045 0.0056 0.0056
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0005 0.0005
Brugia malayi SH2 domain containing protein 0.0015 0.0005 0.0005
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0016 0.0006 0.0006
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0046 0.0057 0.0057
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0023 0.002 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0045 0.0056 0.0056
Echinococcus granulosus tyrosine protein kinase Src42A 0.0059 0.008 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0167 0.0263 0.0263
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0015 0.0005 0.0005
Brugia malayi SH2 domain containing protein 0.0015 0.0005 0.0005
Plasmodium vivax plasmepsin IV, putative 0.0019 0.0012 0.0017
Onchocerca volvulus 0.0045 0.0056 0.0307
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0018 0.0011 0.0037
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0023 0.002 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus granulosus tyrosine protein kinase Src64B 0.0059 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.003
Echinococcus multilocularis cyclin dependent kinase 0.0051 0.0067 0.0067
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.008 0.008
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0023 0.002 0.0107
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0023 0.002 0.0107
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.008 0.008
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.005 0.0545
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0056 0.0056
Trypanosoma cruzi cdc2-related kinase 1 0.0051 0.0067 0.0481
Echinococcus granulosus SH2 domain containing protein 7 0.0015 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0239
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0023 0.002 0.0183
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0239
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0045 0.0056 0.0056
Schistosoma mansoni vav2 0.0015 0.0005 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0211 0.0211
Echinococcus granulosus c src tyrosine kinase 0.0028 0.0028 0.0028
Echinococcus granulosus carnitine O palmitoyltransferase 2 0.0027 0.0025 0.0025
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0015 0.0174
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0056 0.0056
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0084 0.108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus granulosus neuropeptide s receptor 0.0045 0.0056 0.0056
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1002 0.1673 0.1673
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0103 0.0154 0.2075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Brugia malayi sulfakinin receptor protein 0.0045 0.0056 0.0056
Brugia malayi Dopamine receptor protein 2 0.0045 0.0056 0.0056
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0761 0.1265 0.1265
Echinococcus granulosus neuroglian 0.0029 0.0029 0.0029
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.0027 0.0025 0.0025
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0056 0.0056
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.005 0.0234
Brugia malayi cytokine inducible SH2-containing protein 5 0.0015 0.0005 0.0005
Echinococcus granulosus cyclin dependent kinase 5 0.0051 0.0067 0.0067
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0051 0.0067 0.0481
Brugia malayi hypothetical protein 0.0024 0.0021 0.0021
Onchocerca volvulus 0.0045 0.0056 0.0307
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0023 0.002 0.002
Echinococcus multilocularis SHC transforming protein 3 0.0015 0.0005 0.0005
Mycobacterium ulcerans carboxylesterase, LipT 0.1002 0.1673 1
Entamoeba histolytica hypothetical protein 0.0039 0.0046 0.06
Echinococcus granulosus acetylcholinesterase 0.5933 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0005 0.0005
Brugia malayi amine oxidase, flavin-containing family protein 0.0046 0.0057 0.0057
Plasmodium vivax SET domain protein, putative 0.0062 0.0084 0.1023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0045 0.0056 0.0056
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0153
Schistosoma mansoni ap endonuclease 0.0018 0.0011 0.0011
Schistosoma mansoni suppressor of cytokine signaling 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0023 0.002 0.002
Onchocerca volvulus 0.0024 0.0021 0.0098
Onchocerca volvulus 0.1002 0.1673 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0026 0.0025 0.0025
Echinococcus granulosus carboxylesterase 5A 0.5933 1 1
Schistosoma mansoni opsin-like receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0056 0.0056
Schistosoma mansoni tensin 0.0015 0.0005 0.0005
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0011 0.5
Brugia malayi Pepsin A precursor 0.0019 0.0012 0.0012
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0027 0.0025 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus granulosus 7tm_1 domain containing protein 0.0045 0.0056 0.0056
Onchocerca volvulus 0.016 0.0251 0.1474
Loa Loa (eye worm) hypothetical protein 0.1002 0.1673 0.1673
Schistosoma mansoni hypothetical protein 0.0057 0.0076 0.0076
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0027 0.0025 0.0153
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0153
Echinococcus granulosus allatostatin A receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0159 0.0891
Onchocerca volvulus 0.0147 0.0228 0.1336
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.0012 0.0012
Plasmodium falciparum plasmepsin IX 0.0019 0.0012 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0023 0.002 0.0088
Entamoeba histolytica protein kinase rad3, putative 0.0023 0.002 0.0239
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.008 0.008
Schistosoma mansoni amine GPCR 0.0045 0.0056 0.0056
Entamoeba histolytica protein kinase, putative 0.0041 0.0049 0.064
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0023 0.002 0.0107
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0103 0.0154 0.2044
Schistosoma mansoni shc transforming protein 0.0015 0.0005 0.0005
Plasmodium vivax aspartyl protease, putative 0.0019 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0761 0.1265 1
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0019 0.0012 0.0012
Echinococcus multilocularis 0.0023 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0025
Schistosoma mansoni neuropeptide receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi Variant SH3 domain containing protein 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0045 0.0056 0.0307
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0045 0.0056 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0159 0.0159
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0045 0.0056 0.0056
Plasmodium vivax protein kinase Crk2 0.0051 0.0067 0.0779
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0019 0.0012 0.0012
Echinococcus multilocularis allatostatin A receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0049 0.0063 0.0723
Trypanosoma cruzi choline/carnitine O-acetyltransferase, putative 0.0027 0.0025 0.0153
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0023 0.002 0.0107
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0006 0.0002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0011 0.0039
Echinococcus granulosus tyrosine protein kinase Blk 0.0055 0.0074 0.0074
Plasmodium vivax hypothetical protein, conserved 0.0023 0.002 0.0121
Echinococcus multilocularis signal transduction protein lnk realted 0.0015 0.0005 0.0005
Echinococcus granulosus peptide allatostatin:somatostatin 0.0045 0.0056 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0159 0.0891
Leishmania major hypothetical protein, conserved 0.0023 0.002 0.0107
Brugia malayi SH2 domain containing protein 0.0015 0.0005 0.0005
Brugia malayi SH2 domain containing protein 0.0015 0.0005 0.0005
Leishmania major phosphatidylinositol 3-kinase, putative 0.0103 0.0154 0.1172
Echinococcus multilocularis serotonin receptor 0.0045 0.0056 0.0056
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0055 0.0074 0.0074
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0023 0.002 0.0107
Brugia malayi putative neuropeptide receptor NPR1 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0027 0.0025 0.0122
Trypanosoma brucei protein kinase, putative 0.0016 0.0006 0.0002
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0044 0.0524
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0406 0.0666 0.3938
Loa Loa (eye worm) hypothetical protein 0.0167 0.0263 0.0263
Echinococcus granulosus neuropeptide receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0088 0.0088
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni SH2A 0.0015 0.0005 0.0005
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0056 0.0056
Echinococcus granulosus orexin receptor type 2 0.0045 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0045 0.0056 0.0056
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0045 0.0056 0.0307
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0103 0.0154 0.0154
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0217 0.0217
Echinococcus granulosus expressed conserved protein 0.0015 0.0005 0.0005
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0023 0.002 0.0183
Echinococcus multilocularis plexin a4 0.0022 0.0017 0.0017
Plasmodium falciparum plasmepsin V 0.0019 0.0012 0.008
Giardia lamblia Kinase, CMGC GSK 0.0442 0.0726 1
Loa Loa (eye worm) hypothetical protein 0.0278 0.0449 0.0449
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.0057
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0023 0.002 0.0107
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0067 0.0335
Loa Loa (eye worm) SH2 domain-containing protein 0.0015 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0046 0.0057 0.0057
Echinococcus multilocularis rho associated protein kinase 0.016 0.0251 0.0251
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0023 0.002 0.0239
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0103 0.0154 0.0154
Brugia malayi hypothetical protein 0.0019 0.0012 0.0012
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0039 0.0046 0.06
Echinococcus granulosus neuroligin 0.1002 0.1673 0.1673
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Brugia malayi Fibronectin type III domain containing protein 0.0026 0.0025 0.0025
Echinococcus granulosus tyrosine kinase 0.0024 0.0021 0.0021
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0006 0.0006
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0103 0.0154 0.0154
Brugia malayi serine/threonine-protein kinase plk-2 0.0106 0.0159 0.0159
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0106 0.0159 0.0159
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0015 0.0005 0.0005
Trypanosoma cruzi UDP-galactopyranose mutase 0.0046 0.0057 0.0407
Brugia malayi Immunoglobulin I-set domain containing protein 0.0186 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.1002 0.1673 0.1673
Trypanosoma brucei protein kinase, putative 0.0442 0.0726 0.5723
Mycobacterium tuberculosis Conserved hypothetical protein 0.0046 0.0057 0.0279
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0027 0.0025 0.0153
Echinococcus multilocularis SH2 motif 0.0015 0.0005 0.0005
Echinococcus multilocularis cyclin dependent kinase 5 0.0051 0.0067 0.0067
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0103 0.0154 0.2044
Giardia lamblia Kinase, CMGC CDK 0.0051 0.0067 0.0779
Echinococcus multilocularis neuroglian 0.0029 0.0029 0.0029
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0103 0.0154 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0023 0.002 0.0107
Echinococcus multilocularis acetylcholinesterase 0.5933 1 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis g-protein coupled receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Leishmania major phosphatidylinositol kinase related protein, putative 0.0023 0.002 0.0107
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0023 0.002 0.0183
Plasmodium falciparum plasmepsin IV 0.0019 0.0012 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0159 0.0891
Echinococcus granulosus choline O acetyltransferase 0.0179 0.0283 0.0283
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0445 0.0732 0.0732
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0051 0.0067 0.0067
Loa Loa (eye worm) plexin A 0.0022 0.0017 0.0017
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0056 0.0056
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0051 0.0067 0.0067
Echinococcus multilocularis tyrosine kinase 0.0024 0.0021 0.0021
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0442 0.0726 0.0726
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0048 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0422 0.0692 0.946
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0088 0.0088
Onchocerca volvulus 0.0045 0.0056 0.0307
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0023 0.002 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0084 0.0084
Brugia malayi Eukaryotic aspartyl protease family protein 0.0019 0.0012 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Brugia malayi G protein-coupled receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0015 0.0005 0.0005
Plasmodium falciparum glycogen synthase kinase 3 0.0442 0.0726 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.5933 1 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0057 0.0057
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.005 0.0605
Echinococcus granulosus tyrosine protein kinase ABL1 0.0024 0.0021 0.0021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0056 0.0056
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0011 0.0039
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0445 0.0732 0.5764
Schistosoma mansoni opsin-like receptor 0.0045 0.0056 0.0056
Mycobacterium tuberculosis Possible oxidoreductase 0.0046 0.0057 0.0279
Schistosoma mansoni tyrosine kinase 0.0235 0.0378 0.0378
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.0027 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni ap endonuclease 0.0018 0.0011 0.0011
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0023 0.002 0.002
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0103 0.0154 0.0858
Schistosoma mansoni tyrosine kinase 0.0059 0.008 0.008
Echinococcus multilocularis tensin 0.0015 0.0005 0.0005
Schistosoma mansoni biogenic amine receptor 0.0045 0.0056 0.0056
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0046 0.0057 0.0708
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0023 0.002 0.0107
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0056 0.0056
Brugia malayi follicle stimulating hormone receptor 0.0045 0.0056 0.0056
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0024 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0006 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0153
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0088 0.0088
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0056 0.0056
Schistosoma mansoni adapter molecule crk 0.0019 0.0012 0.0012
Echinococcus multilocularis dro:myosuppressin receptor 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0024 0.0021 0.0098
Leishmania major UDP-galactopyranose mutase 0.0046 0.0057 0.0407
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Brugia malayi G-protein coupled receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0056 0.0056
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0015 0.0005 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0445 0.0732 0.0732
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0015 0.0005 0.0005
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0045 0.0056 0.0056
Echinococcus multilocularis G-protein coupled receptor, putative 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus multilocularis c Jun NH2 terminal kinase 0.025 0.0403 0.0403
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0046 0.0057 0.0057
Onchocerca volvulus 0.0019 0.0012 0.0043
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0023 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0023 0.002 0.0107
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi SRC-1 0.0059 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.1002 0.1673 0.1673
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0025
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0045 0.0056 0.0056
Trypanosoma brucei cdc2-related kinase 1 0.0051 0.0067 0.0481
Brugia malayi RE15519p 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0024 0.0021 0.0098
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0046 0.0057 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0023 0.002 0.0052
Echinococcus granulosus roundabout 2 0.0032 0.0035 0.0035
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0045 0.0056 0.0056
Schistosoma mansoni tyrosine kinase 0.0028 0.0028 0.0028
Schistosoma mansoni kinase 0.0057 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.008 0.008
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0239
Leishmania major carnitine/choline acetyltransferase, putative 0.0027 0.0025 0.0153
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0239
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni amine GPCR 0.0045 0.0056 0.0056
Echinococcus granulosus tensin 0.0015 0.0005 0.0005
Brugia malayi plexin A 0.0022 0.0017 0.0017
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0419 0.0689 0.9409
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0015 0.0005 0.0005
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0128 0.0197 0.2666
Schistosoma mansoni neuropeptide receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.1002 0.1673 0.1673
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.003 0.003 0.003
Giardia lamblia Kinase, PLK 0.0106 0.0159 0.207
Brugia malayi SH2 domain containing protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Schistosoma mansoni protein kinase 0.0016 0.0006 0.0006
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Plasmodium vivax aspartyl protease, putative 0.0019 0.0012 0.0017
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0056 0.0056
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0142 0.022 0.2981
Brugia malayi hypothetical protein 0.1002 0.1673 0.1673
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0088 0.0652
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0045 0.0056 0.0307
Echinococcus multilocularis tyrosine protein kinase Blk 0.0055 0.0074 0.0074
Mycobacterium ulcerans oxidoreductase 0.0046 0.0057 0.0307
Brugia malayi Dopamine receptor 0.0045 0.0056 0.0056
Echinococcus granulosus suppressor of cytokine signaling 7 0.0015 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0039 0.0046 0.06
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.0057
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0011 0.0029
Schistosoma mansoni amine GPCR 0.0045 0.0056 0.0056
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0023 0.002 0.0107
Brugia malayi Pre-SET motif family protein 0.0062 0.0084 0.0084
Entamoeba histolytica protein kinase domain containing protein 0.0442 0.0726 0.9929
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0057 0.0649
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0059 0.008 0.008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0046 0.0046
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0442 0.0726 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0023 0.002 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0055 0.0074 0.0074
Brugia malayi Variant SH3 domain containing protein 0.0019 0.0012 0.0012
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0012 0.0001 0.0001
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0051 0.0067 0.0481
Onchocerca volvulus 0.0488 0.0805 0.4795
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0023 0.002 0.002
Echinococcus multilocularis para nitrobenzyl esterase 0.1002 0.1673 0.1673
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0128 0.0197 0.1514
Brugia malayi Plexin repeat family protein 0.0018 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0039 0.0046 0.06
Loa Loa (eye worm) phosphatidylinositol 3 0.0023 0.002 0.002
Entamoeba histolytica cell division protein kinase 2, putative 0.0051 0.0067 0.0885
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0005 0.0005
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0027 0.0025 0.0153
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0445 0.0732 0.4335
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0067 0.0067
Schistosoma mansoni plexin 0.0018 0.0011 0.0011
Brugia malayi Serotonin receptor 0.0045 0.0056 0.0056
Brugia malayi Carboxylesterase family protein 0.1002 0.1673 0.1673
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0045 0.0056 0.0056
Echinococcus multilocularis SH2 motif 0.0015 0.0005 0.0005
Echinococcus multilocularis geminin 0.0164 0.0258 0.0258
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0044 0.0197
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0088 0.0652
Onchocerca volvulus 0.1002 0.1673 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0067 0.0335
Brugia malayi cell division control protein 2 homolog 0.0051 0.0067 0.0067
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0044 0.0464
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0044 0.0575
Schistosoma mansoni GTPase activating protein 0.0015 0.0005 0.0005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0023 0.002 0.002
Onchocerca volvulus 0.0045 0.0056 0.0307
Schistosoma mansoni alpha-1 adrenergic receptor 0.0045 0.0056 0.0056
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0088 0.0088
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0103 0.0154 0.1172
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0056 0.0056
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0043 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0023 0.002 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0011 0.0039
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.025 0.0403 0.0403
Echinococcus granulosus suppressor of cytokine signaling 6 0.0015 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Brugia malayi G-protein coupled receptor 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0027 0.0025 0.0122
Onchocerca volvulus 0.0027 0.0025 0.0122
Schistosoma mansoni hypothetical protein 0.0164 0.0258 0.0258
Echinococcus multilocularis tyrosine protein kinase Abl 0.0028 0.0028 0.0028
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0445 0.0732 0.0732
Schistosoma mansoni neuropeptide f receptor 76f 0.0045 0.0056 0.0056
Echinococcus granulosus serotonin receptor 0.0045 0.0056 0.0056
Brugia malayi Tensin 0.0015 0.0005 0.0005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0011 0.0011
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.0027 0.0025 0.0153
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Echinococcus granulosus alpha 1A adrenergic receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.1002 0.1673 0.1673
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0105 0.0157 0.1201
Echinococcus granulosus family S9 non peptidase ue S09 family 0.1002 0.1673 0.1673
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi Carboxylesterase family protein 0.5933 1 1
Echinococcus multilocularis Zinc finger, PHD finger 0.0103 0.0154 0.0154
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0059 0.008 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0045 0.0056 0.0307
Chlamydia trachomatis protoporphyrinogen oxidase 0.0046 0.0057 0.5
Brugia malayi Variant SH3 domain containing protein 0.0015 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.008 0.008
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0019 0.0012 0.0012
Leishmania major phosphatidylinositol 3-kinase, putative 0.0023 0.002 0.0107
Schistosoma mansoni amine oxidase 0.0046 0.0057 0.0057
Brugia malayi Protein kinase domain containing protein 0.0024 0.0021 0.0021
Echinococcus granulosus rho-associated protein kinase 1 0.016 0.0251 0.0251
Brugia malayi SH2 domain containing protein 0.0024 0.0021 0.0021
Echinococcus multilocularis cyclin dependent kinase 1 0.0051 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.002
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0019 0.0012 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Brugia malayi ORL1-like opioid receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0043 0.0043
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0406 0.0666 0.3938
Echinococcus multilocularis tyrosine protein kinase shark 0.025 0.0402 0.0402
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0046 0.0057 0.0708
Schistosoma mansoni cell adhesion molecule 0.003 0.003 0.003
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0106 0.0159 0.1215
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0442 0.0726 0.0726
Toxoplasma gondii aspartyl protease 0.0019 0.0012 0.008
Echinococcus granulosus g protein coupled receptor 0.0045 0.0056 0.0056
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.1002 0.1673 1
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0103 0.0154 0.2044
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0103 0.0154 0.0154
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0445 0.0732 0.0732
Schistosoma mansoni hypothetical protein 0.0023 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.5933 1 1
Onchocerca volvulus 0.1002 0.1673 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0128 0.0197 0.1117
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0445 0.0732 0.4335
Trypanosoma brucei polo-like protein kinase 0.0106 0.0159 0.1215
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis carboxylesterase 5A 0.5933 1 1
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.0012 0.0017
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0023 0.002 0.002
Giardia lamblia Phosphatidylinositol 4-kinase 0.0023 0.002 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0159 0.0891
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0159 0.0891
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus granulosus NCK adaptor protein 0.0019 0.0012 0.0012
Onchocerca volvulus Serine\/threonine kinase homolog 0.0106 0.0159 0.0924
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0051 0.0067 0.0067
Echinococcus granulosus SH2 domain containing adapter protein F 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0179 0.0283 0.0283
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0026 0.0025 0.0025
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0603 0.0999 0.5944
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0056 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0055 0.0055
Leishmania major hypothetical protein, unknown function 0.0023 0.002 0.0107
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0023 0.002 0.0121
Onchocerca volvulus 0.0154 0.0241 0.1415
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Giardia lamblia Kinase, CMGC GSK 0.0442 0.0726 1
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0046 0.0057 0.0307
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0128 0.0197 0.1514
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.002 0.002
Trypanosoma cruzi cdc2-related kinase 3 0.0051 0.0067 0.0481
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.0027 0.0025 0.0153
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0019 0.0012 0.0012
Echinococcus multilocularis activin receptor type 0.0016 0.0006 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0016 0.0006 0.0058
Echinococcus multilocularis protein kinase shaggy 0.0442 0.0726 0.0726
Brugia malayi Tachykinin-like peptides receptor 99D 0.0045 0.0056 0.0056
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0059 0.008 0.008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0045 0.0056 0.0056
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0023 0.002 0.002
Onchocerca volvulus 0.0019 0.0012 0.0043
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0761 0.1265 0.1265
Schistosoma mansoni hypothetical protein 0.0045 0.0056 0.0056
Plasmodium falciparum plasmepsin VI 0.0019 0.0012 0.008
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.0027 0.0025 0.0025
Loa Loa (eye worm) phosphatidylinositol 3 0.0023 0.002 0.002
Brugia malayi protein-tyrosine kinase 0.0055 0.0074 0.0074
Brugia malayi neuropeptide F receptor 0.0045 0.0056 0.0056
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0055 0.0055
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.002 0.002
Schistosoma mansoni growth hormone secretagogue receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0023 0.002 0.0183
Loa Loa (eye worm) hypothetical protein 0.0032 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.0057
Leishmania major phosphatidylinositol kinase, putative 0.0023 0.002 0.0107
Schistosoma mansoni tensin 0.0015 0.0005 0.0005
Onchocerca volvulus Tyrosine kinase homolog 0.0159 0.0249 0.146
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0025
Echinococcus multilocularis neuropeptide s receptor 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Schistosoma mansoni protein kinase 0.0016 0.0006 0.0006
Echinococcus granulosus signal transduction protein lnk realted 0.0015 0.0005 0.0005
Echinococcus multilocularis 0.0015 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.1002 0.1673 0.1673
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.0057
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0027 0.0025 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus multilocularis cyclin dependent kinase 1 0.0051 0.0067 0.0067
Echinococcus granulosus dro:myosuppressin receptor 0.0045 0.0056 0.0056
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.1002 0.1673 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.0027 0.0025 0.0153
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0128 0.0197 0.0197
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0051 0.0067 0.0838
Loa Loa (eye worm) TK protein kinase 0.0055 0.0074 0.0074
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0088 0.118
Schistosoma mansoni neuropeptide receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0056 0.0056
Schistosoma mansoni acetylcholinesterase 0.1002 0.1673 0.1673
Echinococcus granulosus geminin 0.0164 0.0258 0.0258
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0048 0.0048
Echinococcus granulosus lysine specific histone demethylase 1A 0.0046 0.0057 0.0057
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0059 0.008 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0056 0.0056
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.002
Trypanosoma brucei carnitine O-acetyltransferase, putative 0.0027 0.0025 0.0153
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0011 0.012
Schistosoma mansoni amine oxidase 0.0046 0.0057 0.0057
Onchocerca volvulus 0.0442 0.0726 0.4324
Echinococcus granulosus SH2 motif 0.0015 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0024 0.0021 0.0021
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0023 0.002 0.002
Brugia malayi Choline O-acetyltransferase 0.0179 0.0283 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Brugia malayi Immunoglobulin I-set domain containing protein 0.0012 0.0001 0.0001
Onchocerca volvulus 0.1002 0.1673 1
Plasmodium falciparum plasmepsin VIII, putative 0.0019 0.0012 0.008
Brugia malayi Stress-activated protein kinase jnk-1 0.025 0.0403 0.0403
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0045 0.0056 0.0056
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0057 0.0649
Brugia malayi Protein kinase domain containing protein 0.0024 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0025
Schistosoma mansoni tensin-related 0.0015 0.0005 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.005 0.005
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0128 0.0197 0.1117
Onchocerca volvulus 0.0045 0.0056 0.0307
Onchocerca volvulus 0.0045 0.0056 0.0307
Echinococcus granulosus twitchin 0.0035 0.0039 0.0039
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0103 0.0154 0.0154
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0103 0.0154 0.1993
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.0012 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus granulosus tyrosine protein kinase HCK 0.0041 0.0049 0.0049
Trichomonas vaginalis spcc417.12 protein, putative 0.1002 0.1673 1
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0003 0.0003
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.0159 0.2151
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0045 0.0056 0.0056
Trypanosoma cruzi cdc2-related kinase 3 0.0051 0.0067 0.0481
Echinococcus multilocularis N chimaerin 0.0015 0.0005 0.0005
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0045 0.0056 0.0056
Leishmania major C-8 sterol isomerase-like protein 0.0761 0.1265 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0045 0.0056 0.0056
Brugia malayi Cytochrome P450 family protein 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0419 0.0689 0.9409
Schistosoma mansoni tyrosine kinase 0.0024 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0025
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0046 0.0057 0.0708
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0023 0.002 0.0183
Entamoeba histolytica cell division protein kinase 2, putative 0.0051 0.0067 0.0885
Onchocerca volvulus 0.0045 0.0056 0.0307
Echinococcus multilocularis G protein coupled receptor 139 0.0045 0.0056 0.0056
Echinococcus multilocularis conserved hypothetical protein 0.0671 0.1114 0.1114
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0011 0.0039
Loa Loa (eye worm) phosphatidylinositol kinase 0.0023 0.002 0.002
Loa Loa (eye worm) choline O-acetyltransferase 0.0179 0.0283 0.0283
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0015 0.0005 0.0005
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0023 0.002 0.002
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0128 0.0197 0.1117
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0103 0.0154 0.0858
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni tensin 0.0015 0.0005 0.0005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0044 0.0197
Echinococcus granulosus para nitrobenzyl esterase 0.1002 0.1673 0.1673
Schistosoma mansoni myosin xvIII 0.0045 0.0056 0.0056
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0067 0.0335
Brugia malayi SH2 domain containing protein 0.0024 0.0021 0.0021
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Echinococcus granulosus g protein coupled receptor 0.0045 0.0056 0.0056
Onchocerca volvulus 0.0027 0.0025 0.0122
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Onchocerca volvulus Neuropeptide F receptor homolog 0.0045 0.0056 0.0307
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.0705 0.0705
Echinococcus multilocularis 0.0046 0.0057 0.0057
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0023 0.002 0.0107
Echinococcus granulosus tyrosine kinase 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.1002 0.1673 0.1673
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0159 0.1215
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0074 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0159 0.0891
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Echinococcus granulosus tyrosine protein kinase Srms 0.0024 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0028 0.0028 0.0028
Echinococcus granulosus plexin a4 0.0022 0.0017 0.0017
Echinococcus multilocularis orexin receptor type 2 0.0045 0.0056 0.0056
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0106 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0217 0.0217
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.002 0.0107
Brugia malayi hypothetical protein 0.0039 0.0046 0.0046
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0025 0.0153
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0027 0.0025 0.0025
Schistosoma mansoni fkbp-rapamycin associated protein 0.0023 0.002 0.002
Echinococcus multilocularis protoporphyrinogen oxidase 0.0046 0.0057 0.0057
Brugia malayi SH2 domain containing protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Loa Loa (eye worm) melatonin receptor type 1A 0.0045 0.0056 0.0056
Schistosoma mansoni neuroligin 3 (S09 family) 0.1002 0.1673 0.1673
Echinococcus multilocularis serotonin receptor 0.0045 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0045 0.0056 0.0056
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0649 0.1076 0.6418
Schistosoma mansoni adenoreceptor 0.0045 0.0056 0.0056
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0015 0.0005 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0025 0.0025
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.5933 1 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0059 0.008 0.008
Loa Loa (eye worm) TK/ROR protein kinase 0.0012 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0024 0.0021 0.0021
Onchocerca volvulus 0.1002 0.1673 1
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Brugia malayi larval opioid receptor 0.0045 0.0056 0.0056
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0023 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Onchocerca volvulus 0.0045 0.0056 0.0307
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Brugia malayi G protein-coupled receptor F59B2.13 0.0045 0.0056 0.0056
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0027 0.0025 0.0025
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0026 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Trichomonas vaginalis set domain proteins, putative 0.0488 0.0805 0.4777
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Brugia malayi SWIRM domain containing protein 0.0046 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0046 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0056 0.0056
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.002 0.002
Brugia malayi Carboxylesterase family protein 0.1002 0.1673 0.1673
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.002 0.0052
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0056 0.0056
Toxoplasma gondii target of rapamycin (TOR), putative 0.0023 0.002 0.0183
Giardia lamblia Kinase, CMGC CDK 0.0051 0.0067 0.0779
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0025
Loa Loa (eye worm) TK/FER protein kinase 0.0024 0.0021 0.0021
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0005 0.0005
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0167 0.0263 0.0263
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0056 0.0056
Schistosoma mansoni biogenic amine receptor 0.0045 0.0056 0.0056
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1002 0.1673 0.1673
Toxoplasma gondii exonuclease III APE 0.0018 0.0011 0.0064
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0046 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0153
Trypanosoma brucei cdc2-related kinase 3 0.0051 0.0067 0.0481
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0024 0.0021 0.0098
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0012 0.0012
Echinococcus multilocularis tyrosine protein kinase HCK 0.0041 0.0049 0.0049
Echinococcus granulosus somatostatin receptor 0.0045 0.0056 0.0056
Echinococcus granulosus 7TM GPCR rhodopsin 0.0045 0.0056 0.0056
Echinococcus granulosus hypothetical protein 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0045 0.0056 0.0307
Echinococcus granulosus lysine specific histone demethylase 1A 0.0046 0.0057 0.0057
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0056 0.0056
Schistosoma mansoni tensin-related 0.0015 0.0005 0.0005
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0084 0.0084
Loa Loa (eye worm) SH2 domain-containing protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0023 0.002 0.0107
Schistosoma mansoni histamine h1 receptor 0.0045 0.0056 0.0056
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.002 0.0107
Onchocerca volvulus 0.0062 0.0084 0.0475
Brugia malayi Variant SH3 domain containing protein 0.0019 0.0012 0.0012
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0024 0.0021 0.0262
Schistosoma mansoni hypothetical protein 0.0045 0.0056 0.0056
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0103 0.0154 0.0154
Onchocerca volvulus 0.0045 0.0056 0.0307
Echinococcus granulosus neuropeptide FF receptor 2 0.0045 0.0056 0.0056
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0056 0.0056
Brugia malayi AKH receptor 0.0045 0.0056 0.0056
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0106 0.0159 0.0159
Schistosoma mansoni memapsin-2 (A01 family) 0.0471 0.0776 0.0776
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0167 0.0263 0.0263
Brugia malayi aspartic protease BmAsp-1, identical 0.0019 0.0012 0.0012
Echinococcus granulosus cyclin dependent kinase 0.0051 0.0067 0.0067
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0023 0.002 0.0107
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0019 0.0012 0.008
Echinococcus granulosus BC026374 protein S09 family 0.1002 0.1673 0.1673
Brugia malayi hypothetical protein 0.0045 0.0056 0.0056
Schistosoma mansoni protein kinase 0.0016 0.0006 0.0006
Echinococcus multilocularis neuropeptide FF receptor 2 0.0045 0.0056 0.0056
Trypanosoma brucei carnitine O-palmitoyltransferase, putative 0.0027 0.0025 0.0153
Echinococcus multilocularis choline O acetyltransferase 0.0179 0.0283 0.0283
Schistosoma mansoni choline o-acyltransferase 0.0179 0.0283 0.0283
Loa Loa (eye worm) carboxylesterase 0.1002 0.1673 0.1673
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0389 0.0637 0.0637
Echinococcus granulosus cyclin dependent kinase 1 0.0051 0.0067 0.0067

Activities

Activity type Activity value Assay description Source Reference
Drug metabolism (ADMET) = 43 % Drug metabolism in human liver microsomes at 2 uM after 0.5 hr by LC/MS/MS analysis ChEMBL. 25466177
EC50 (functional) = 12.5 nM Agonist activity at human CB2 receptor expressed in CHO cells by [35S]-GTPgammaS binding assay ChEMBL. 25466177
EC50 (functional) = 5000 nM Agonist activity at human CB1 receptor expressed in Sf9 cells by [35S]-GTPgammaS binding assay ChEMBL. 25466177
Efficacy (functional) = 43.2 % Agonist activity at human CB1 receptor expressed in Sf9 cells by [35S]-GTPgammaS binding assay relative to control ChEMBL. 25466177
Efficacy (functional) = 72.6 % Agonist activity at human CB2 receptor expressed in CHO cells by [35S]-GTPgammaS binding assay relative to control ChEMBL. 25466177

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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