Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Biotin lipoyl attachment | 0.0051 | 0.0252 | 0.0271 |
Trypanosoma cruzi | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0051 | 0.0252 | 0.0356 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.004 | 0.0181 | 0.0181 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0139 | 0.0139 |
Trypanosoma cruzi | glutamine-dependent carbamoyl-phosphate synthetase, putative | 0.0125 | 0.0729 | 0.12 |
Mycobacterium ulcerans | acetyl-/propionyl-CoA carboxylase subunit beta | 0.0197 | 0.1192 | 0.3322 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0554 | 0.3487 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.0722 | 0.0755 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0171 | 0.0131 |
Plasmodium vivax | SET domain protein, putative | 0.006 | 0.0312 | 0.0395 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0839 | 0.532 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0139 | 0.0139 |
Plasmodium falciparum | dihydrolipoamide acyltransferase component E2 | 0.0051 | 0.0252 | 0.0304 |
Echinococcus granulosus | propionyl coenzyme A carboxylase beta chain | 0.0197 | 0.1192 | 0.1284 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.023 | 0.0248 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.1455 | 0.9279 | 1 |
Toxoplasma gondii | 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein | 0.0051 | 0.0252 | 0.0219 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0021 | 0.0062 | 0.0081 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0839 | 0.532 | 1 |
Mycobacterium tuberculosis | DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase | 0.0051 | 0.0252 | 0.0587 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0103 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0197 | 0.1192 | 0.2015 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0144 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.006 | 0.0312 | 0.0336 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0171 | 0.023 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.0722 | 0.0755 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0613 | 0.3832 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0171 | 0.0154 |
Trypanosoma brucei | 2-oxoglutarate dehydrogenase E2 component, putative | 0.0051 | 0.0252 | 0.0219 |
Mycobacterium tuberculosis | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) | 0.0197 | 0.1192 | 0.3322 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0554 | 0.3487 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.033 | 0.0304 |
Brugia malayi | isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0124 |
Brugia malayi | Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor | 0.0051 | 0.0252 | 0.0245 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0041 | 0.0189 | 0.0204 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.033 | 0.0356 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0717 | 0.4538 | 0.489 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.023 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0312 | 0.0295 |
Onchocerca volvulus | Huntingtin homolog | 0.0109 | 0.0627 | 0.1183 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0171 | 0.0214 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0062 | 0.0032 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0505 | 0.3173 | 0.3173 |
Trichomonas vaginalis | set domain proteins, putative | 0.0479 | 0.3004 | 0.5604 |
Trypanosoma cruzi | acetyl-CoA carboxylase, putative | 0.0197 | 0.1192 | 0.2015 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.023 | 0.0248 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0072 | 0.0389 | 0.0398 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0171 | 0.0171 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.004 | 0.0181 | 0.0142 |
Plasmodium vivax | carbamoyl phosphate synthetase, putative | 0.0125 | 0.0729 | 0.1023 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1984 | 0.2173 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0505 | 0.3173 | 0.3173 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.004 | 0.0181 | 0.0232 |
Brugia malayi | hypothetical protein | 0.032 | 0.1984 | 0.2188 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0093 | 0.0047 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0171 | 0.0131 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.058 | 0.3655 | 0.6841 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0125 | 0.0729 | 0.0786 |
Plasmodium falciparum | carbamoyl phosphate synthetase | 0.0125 | 0.0729 | 0.1023 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0554 | 0.3487 | 0.3758 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0554 | 0.3487 | 1 |
Trypanosoma brucei | glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative | 0.0125 | 0.0729 | 0.0736 |
Leishmania major | propionyl-coa carboxylase beta chain, putative | 0.0197 | 0.1192 | 0.1237 |
Mycobacterium ulcerans | hypothetical protein | 0.0051 | 0.0252 | 0.0587 |
Mycobacterium tuberculosis | Biotinylated protein TB7.3 | 0.0051 | 0.0252 | 0.0587 |
Onchocerca volvulus | 0.032 | 0.1984 | 0.54 | |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0139 | 0.015 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.004 | 0.0181 | 0.0181 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0093 | 0.0066 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0246 | 0.1505 | 0.1505 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.033 | 0.0304 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.0505 | 0.3173 | 0.3384 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0389 | 0.0419 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.0062 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0139 | 0.015 |
Trypanosoma cruzi | glutamine dependent carbamoyl-phosphate synthase, putative | 0.0125 | 0.0729 | 0.12 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.033 | 0.0815 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.1455 | 0.9279 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0312 | 0.0336 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.033 | 0.0356 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0085 | 0.0473 | 0.0493 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.004 | 0.0181 | 0.0165 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.033 | 0.0815 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0144 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0944 | 0.5995 | 0.5995 |
Brugia malayi | Pre-SET motif family protein | 0.006 | 0.0312 | 0.0313 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0145 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0252 | 0.0227 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.1455 | 0.9279 | 0.9279 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0421 | 0.263 | 0.2898 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0312 | 0.0336 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0107 | 0.0613 | 0.0661 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0551 | 0.3465 | 0.6479 |
Trypanosoma brucei | dihydrolipoamide acetyltransferase E2 subunit, putative | 0.0051 | 0.0252 | 0.0219 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0085 | 0.0473 | 0.0476 |
Trypanosoma brucei | dihydrolipoamide branched chain transacylase, putative | 0.0051 | 0.0252 | 0.0219 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0839 | 0.532 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0085 | 0.0473 | 0.051 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0058 | 0.0298 | 0.0321 |
Schistosoma mansoni | hypothetical protein | 0.0368 | 0.2294 | 0.2472 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.058 | 0.3655 | 0.6841 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.1053 | 0.6694 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0085 | 0.0473 | 0.0473 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0106 | 0.0604 | 0.0639 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0046 | 0.0218 | 0.0207 |
Schistosoma mansoni | propionyl-CoA carboxylase beta chain mitochondrial precursor | 0.0197 | 0.1192 | 0.1284 |
Mycobacterium ulcerans | acetyl/propionyl CoA carboxylase subunit beta | 0.0197 | 0.1192 | 0.3322 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0246 | 0.1505 | 0.1622 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0144 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.004 | 0.0181 | 0.0893 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.004 | 0.0181 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0473 | 0.0476 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.005 | 0.005 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.023 | 0.023 |
Brugia malayi | Isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0124 |
Brugia malayi | P38 map kinase family protein 2 | 0.0505 | 0.3173 | 0.3521 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0389 | 0.0381 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.033 | 0.0815 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0613 | 0.3832 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.005 | 0.0054 |
Echinococcus multilocularis | geminin | 0.0368 | 0.2294 | 0.2294 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0106 | 0.0604 | 0.0622 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | CMGC/MAPK/JNK protein kinase | 0.0251 | 0.1537 | 0.1671 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0197 | 0.1192 | 0.2015 |
Echinococcus multilocularis | dihydrolipoyllysine residue acetyltransferase | 0.0051 | 0.0252 | 0.0252 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.023 | 0.022 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0554 | 0.3487 | 0.3725 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0246 | 0.0266 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0107 | 0.0613 | 0.0613 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0021 | 0.0062 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0246 | 0.1505 | 0.165 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0171 | 0.0214 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0554 | 0.3487 | 0.6067 |
Wolbachia endosymbiont of Brugia malayi | branched-chain alpha-keto acid dehydrogenase subunit E2 | 0.0051 | 0.0252 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0252 | 0.0227 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.1455 | 0.9279 | 1 |
Echinococcus multilocularis | Biotin lipoyl attachment | 0.0051 | 0.0252 | 0.0252 |
Echinococcus multilocularis | c Jun NH2 terminal kinase | 0.0251 | 0.1537 | 0.1537 |
Entamoeba histolytica | recQ family helicase, putative | 0.0021 | 0.0062 | 0.0081 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0034 | 0.0144 | 0.0142 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.023 | 0.0248 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0255 | 0.1564 | 0.1702 |
Mycobacterium leprae | Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) | 0.0197 | 0.1192 | 0.3131 |
Brugia malayi | Cytochrome P450 family protein | 0.0044 | 0.0204 | 0.0191 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.0062 | 0.0023 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0554 | 0.3487 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.0505 | 0.3173 | 0.342 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.023 | 0.023 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0156 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0062 | 0.0013 |
Schistosoma mansoni | aspartate carbamoyltransferase | 0.0125 | 0.0729 | 0.0786 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0554 | 0.3487 | 0.3758 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0181 | 0.0249 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0551 | 0.3465 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0156 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0551 | 0.3465 | 0.6479 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase, putative | 0.0051 | 0.0252 | 0.0356 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0021 | 0.0062 | 0.0013 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0093 | 0.0066 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0046 | 0.0218 | 0.0189 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0554 | 0.3487 | 0.3725 |
Mycobacterium tuberculosis | Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 | 0.0197 | 0.1192 | 0.3322 |
Toxoplasma gondii | dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase | 0.0051 | 0.0252 | 0.0219 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0139 | 0.01 |
Schistosoma mansoni | intermediate filament proteins | 0.0085 | 0.0473 | 0.051 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.004 | 0.0181 | 0.0195 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0717 | 0.4538 | 0.4538 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0062 | 0.0018 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0505 | 0.3173 | 0.5513 |
Leishmania major | dihydrolipoamide acetyltransferase precursorlike protein | 0.0051 | 0.0252 | 0.0219 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.006 | 0.0312 | 0.0312 |
Brugia malayi | Pre-SET motif family protein | 0.0421 | 0.263 | 0.2911 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.1404 | 0.8951 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0255 | 0.1564 | 0.1717 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0139 | 0.015 |
Schistosoma mansoni | dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase | 0.0051 | 0.0252 | 0.0271 |
Echinococcus granulosus | lamin dm0 | 0.0085 | 0.0473 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0139 | 0.01 |
Plasmodium vivax | lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative | 0.0051 | 0.0252 | 0.0304 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0554 | 0.3487 | 0.3487 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0106 | 0.0604 | 0.0639 |
Loa Loa (eye worm) | intermediate filament protein | 0.0085 | 0.0473 | 0.0476 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.004 | 0.0181 | 0.0249 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.004 | 0.0181 | 0.0232 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0551 | 0.3465 | 0.6479 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0839 | 0.532 | 1 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.1455 | 0.9279 | 1 |
Mycobacterium leprae | Probable biotinylated protein homolog TB7.3 | 0.0051 | 0.0252 | 0.0319 |
Schistosoma mansoni | lamin | 0.0085 | 0.0473 | 0.051 |
Giardia lamblia | Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative | 0.0248 | 0.1519 | 1 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.004 | 0.0181 | 0.0195 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0613 | 0.3832 |
Schistosoma mansoni | DNA helicase recq1 | 0.0021 | 0.0062 | 0.0066 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0062 | 0.0032 |
Plasmodium falciparum | lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | 0.0051 | 0.0252 | 0.0304 |
Echinococcus granulosus | neuropeptide s receptor | 0.0944 | 0.5995 | 0.6461 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.033 | 0.0815 |
Mycobacterium leprae | ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 | 0.0197 | 0.1192 | 0.3131 |
Brugia malayi | hypothetical protein | 0.0109 | 0.0627 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0181 | 0.0147 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0034 | 0.0144 | 0.0144 |
Mycobacterium ulcerans | branched-chain alpha-keto acid dehydrogenase subunit E2 | 0.0051 | 0.0252 | 0.0587 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0034 | 0.0144 | 0.0103 |
Onchocerca volvulus | 0.0085 | 0.0473 | 0.0705 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.033 | 0.0356 |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.0554 | 0.3487 | 1 |
Wolbachia endosymbiont of Brugia malayi | carbamoyl phosphate synthase large subunit | 0.0125 | 0.0729 | 0.1977 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0034 | 0.0144 | 0.0167 |
Mycobacterium ulcerans | dihydrolipoamide acetyltransferase | 0.0051 | 0.0252 | 0.0587 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0021 | 0.0062 | 0.0018 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0093 | 0.0047 |
Schistosoma mansoni | pyruvate carboxylase | 0.0554 | 0.3487 | 0.3758 |
Leishmania major | carboxylase, putative | 0.0554 | 0.3487 | 0.3725 |
Trypanosoma cruzi | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0051 | 0.0252 | 0.0356 |
Toxoplasma gondii | acyl-CoA carboxyltransferase beta chain, putative | 0.0197 | 0.1192 | 0.1237 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0139 | 0.0118 |
Chlamydia trachomatis | acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | 0.0197 | 0.1192 | 0.3233 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0171 | 0.0825 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0139 | 0.0118 |
Schistosoma mansoni | DNA helicase recq5 | 0.0021 | 0.0062 | 0.0066 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0139 | 0.015 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0034 | 0.0144 | 0.0275 |
Onchocerca volvulus | 0.0479 | 0.3004 | 0.8567 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0251 | 0.1537 | 0.1657 |
Mycobacterium leprae | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) | 0.0197 | 0.1192 | 0.3131 |
Schistosoma mansoni | dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase | 0.0051 | 0.0252 | 0.0271 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0171 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0627 | 0.0649 |
Plasmodium falciparum | dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex | 0.0051 | 0.0252 | 0.0304 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.0062 | 0.0062 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.0722 | 0.0772 |
Plasmodium vivax | dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative | 0.0051 | 0.0252 | 0.0304 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.0505 | 0.3173 | 0.3509 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0144 | 0.0103 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0021 | 0.0062 | 0.0066 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.005 | 0.0018 |
Schistosoma mansoni | dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase | 0.0051 | 0.0252 | 0.0271 |
Trypanosoma brucei | pyruvate dehydrogenase complex E3 binding protein, putative | 0.0051 | 0.0252 | 0.0219 |
Wolbachia endosymbiont of Brugia malayi | Acetyl-CoA carboxylase, carboxyltransferase component | 0.0197 | 0.1192 | 0.3322 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0107 | 0.0613 | 0.0661 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0189 | 0.0157 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0505 | 0.3173 | 0.3173 |
Brugia malayi | hypothetical protein | 0.0107 | 0.0613 | 0.065 |
Mycobacterium ulcerans | carbamoyl phosphate synthase large subunit | 0.0125 | 0.0729 | 0.1977 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0839 | 0.532 | 1 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.1455 | 0.9279 | 1 |
Toxoplasma gondii | dihydrolipoamide acyltransferase, putative | 0.0051 | 0.0252 | 0.0219 |
Brugia malayi | intermediate filament protein | 0.0085 | 0.0473 | 0.0493 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0554 | 0.3487 | 0.6067 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0944 | 0.5995 | 0.5995 |
Leishmania major | dihydrolipoamide branched chain transacylase, putative | 0.0051 | 0.0252 | 0.0219 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0171 | 0.023 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0093 | 0.0077 |
Trypanosoma cruzi | dihydrolipoamide branched chain transacylase, putative | 0.0051 | 0.0252 | 0.0356 |
Mycobacterium ulcerans | acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 | 0.0197 | 0.1192 | 0.3322 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0551 | 0.3465 | 0.6479 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.0062 | 0.0021 |
Schistosoma mansoni | lamin | 0.0085 | 0.0473 | 0.051 |
Treponema pallidum | pyruvate carboxylase subunit B | 0.0051 | 0.0252 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0171 | 0.0184 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0505 | 0.3173 | 0.5513 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0554 | 0.3487 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.004 | 0.0181 | 0.0249 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0901 | 0.5716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0463 | 0.0464 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.004 | 0.0181 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0604 | 0.0622 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0093 | 0.0067 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.0171 | 0.0353 |
Brugia malayi | Stress-activated protein kinase jnk-1 | 0.0251 | 0.1537 | 0.1686 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0246 | 0.0266 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.0062 | 0.0013 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase precursor, putative | 0.0051 | 0.0252 | 0.0356 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0551 | 0.3465 | 0.6479 |
Mycobacterium leprae | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB | 0.0051 | 0.0252 | 0.0319 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0717 | 0.4538 | 0.489 |
Echinococcus granulosus | dihydrolipoyllysine residue acetyltransferase | 0.0051 | 0.0252 | 0.0271 |
Leishmania major | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0197 | 0.1192 | 0.1237 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0103 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.0062 | 0.0013 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.006 | 0.0312 | 0.0336 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0021 | 0.0062 | 0.0066 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0312 | 0.0336 |
Toxoplasma gondii | pyruvate carboxylase | 0.0554 | 0.3487 | 0.3725 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0093 | 0.0066 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.023 | 0.0248 |
Echinococcus multilocularis | lamin | 0.0085 | 0.0473 | 0.0473 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0044 | 0.0204 | 0.0173 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0041 | 0.0189 | 0.0189 |
Trypanosoma brucei | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0197 | 0.1192 | 0.1237 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0246 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0179 | 0.0145 |
Echinococcus granulosus | c-Jun N-terminal kinases | 0.0251 | 0.1537 | 0.1657 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.0062 | 0.0066 |
Leishmania major | carbamoyl-phosphate synthase, putative | 0.0125 | 0.0729 | 0.0736 |
Trypanosoma cruzi | dihydrolipoamide branched chain transacylase, putative | 0.0051 | 0.0252 | 0.0356 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.005 | 0.0054 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4 | 0.0197 | 0.1192 | 0.3322 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0627 | 0.0649 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0106 |
Trypanosoma cruzi | dihydrolipoamide acetyltransferase precursor, putative | 0.0051 | 0.0252 | 0.0356 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase beta chain | 0.0197 | 0.1192 | 0.1192 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0551 | 0.3465 | 0.6479 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0551 | 0.3465 | 0.6479 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.033 | 0.033 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0125 | 0.0729 | 0.0786 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.004 | 0.0181 | 0.0195 |
Echinococcus granulosus | geminin | 0.0368 | 0.2294 | 0.2472 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0179 | 0.0145 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.004 | 0.0181 | 0.0195 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.1053 | 0.6694 | 1 |
Leishmania major | methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein | 0.0554 | 0.3487 | 0.3725 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 5 AccD5 | 0.0197 | 0.1192 | 0.3322 |
Schistosoma mansoni | hypothetical protein | 0.0368 | 0.2294 | 0.2472 |
Brugia malayi | dihydrolipoamide S-acetyltransferase precursor, putative | 0.0051 | 0.0252 | 0.0245 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0554 | 0.3487 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0505 | 0.3173 | 0.3173 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0062 | 0.0013 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0021 | 0.0062 | 0.0062 |
Schistosoma mansoni | dihydrolipoamide S-acetyltransferase | 0.0051 | 0.0252 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0252 | 0.0227 |
Onchocerca volvulus | 0.006 | 0.0312 | 0.0204 | |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0144 | 0.0167 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0171 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.0613 | 0.0661 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.006 | 0.0312 | 0.0284 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.004 | 0.0181 | 0.0893 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1505 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0093 | 0.0049 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.1404 | 0.8951 | 1 |
Echinococcus multilocularis | musashi | 0.0085 | 0.0473 | 0.0473 |
Echinococcus granulosus | lamin | 0.0085 | 0.0473 | 0.051 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0139 | 0.015 |
Toxoplasma gondii | biotin-requiring enzyme domain-containing protein | 0.0051 | 0.0252 | 0.0219 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0144 | 0.0103 |
Onchocerca volvulus | 0.0085 | 0.0473 | 0.0705 | |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.004 | 0.0181 | 0.0181 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.023 | 0.0248 |
Brugia malayi | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta | 0.0051 | 0.0252 | 0.0245 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0139 | 0.015 |
Leishmania major | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0051 | 0.0252 | 0.0219 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0144 | 0.0144 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0139 | 0.015 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.005 | 0.0054 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0093 | 0.0047 |
Echinococcus granulosus | dihydrolipoyllysine residue succinyltransferase | 0.0051 | 0.0252 | 0.0271 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0839 | 0.532 | 0.5921 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0554 | 0.3487 | 1 |
Chlamydia trachomatis | biotin carboxylase | 0.0503 | 0.316 | 1 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0034 | 0.0144 | 0.0142 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0171 | 0.0353 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0171 | 0.0131 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0839 | 0.532 | 0.5928 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0171 | 0.0184 |
Toxoplasma gondii | carbamoylphosphate synthetase | 0.0125 | 0.0729 | 0.0736 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4_2 | 0.0197 | 0.1192 | 0.3322 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E2 | 0.0051 | 0.0252 | 0.0219 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0944 | 0.5995 | 0.6461 |
Onchocerca volvulus | Huntingtin homolog | 0.0109 | 0.0627 | 0.1183 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide acyltransferase E2 component | 0.0051 | 0.0252 | 0.0587 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.1455 | 0.9279 | 1 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.0505 | 0.3173 | 0.3384 |
Entamoeba histolytica | acetyl-coA carboxylase, putative | 0.0248 | 0.1519 | 1 |
Leishmania major | dihydrolipoamide acetyltransferase precursor, putative | 0.0051 | 0.0252 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0062 | 0.0013 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.0062 | 0.0023 |
Mycobacterium tuberculosis | Probable branched-chain keto acid dehydrogenase E2 component BkdC | 0.0051 | 0.0252 | 0.0587 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0839 | 0.532 | 1 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.0062 | 0.0023 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0171 | 0.0136 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0093 | 0.0077 |
Trypanosoma brucei | unspecified product | 0.0364 | 0.2267 | 0.2402 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0554 | 0.3487 | 0.3758 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.0505 | 0.3173 | 0.342 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.0062 | 0.0013 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.006 | 0.0312 | 0.0312 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.0613 | 0.3832 |
Echinococcus multilocularis | dihydrolipoyllysine residue succinyltransferase | 0.0051 | 0.0252 | 0.0252 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Displacement of [3H]MK801 from NMDA receptor in Sprague-Dawley rat cerebral cortex membrane at 50 umol by liquid scintillation counting | ChEMBL. | 25462263 | |
Activity (binding) | = 85.2 % | Displacement of [3H]EBOB from GABAA receptor in Sprague-Dawley rat frontoparietal cortex membrane at 50 umol by liquid scintillation counting | ChEMBL. | 25462263 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.