Detailed information for compound 948798

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 207.292 | Formula: C11H13NOS
  • H donors: 0 H acceptors: 1 LogP: 3.02 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCSc1ccc(c(c1)OC)C#N
  • InChi: 1S/C11H13NOS/c1-3-6-14-10-5-4-9(8-12)11(7-10)13-2/h4-5,7H,3,6H2,1-2H3
  • InChiKey: SYEDQZDHJDTUDG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens androgen receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Schistosoma mansoni neuropeptide receptor 0.0063 0.0154 0.0317
Trichomonas vaginalis cyclins, putative 0.005 0.0082 0.0215
Onchocerca volvulus 0.0063 0.0154 0.1051
Schistosoma mansoni amine GPCR 0.0063 0.0154 0.0317
Plasmodium falciparum subtilisin-like protease 2 0.004 0.0029 0.0488
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Trichomonas vaginalis cyclins, putative 0.005 0.0082 0.0215
Brugia malayi Will die slowly protein 0.0305 0.1463 0.1463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Trypanosoma cruzi cyclin 6, putative 0.005 0.0082 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0063 0.0154 0.0192
Brugia malayi hypothetical protein 0.0066 0.017 0.017
Echinococcus multilocularis neuropeptide s receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.005 0.0082 0.0082
Onchocerca volvulus 0.0066 0.017 0.1164
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0063 0.0154 0.0317
Echinococcus multilocularis histone lysine n methyltransferase setd8 0.0071 0.0198 0.0247
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0365 0.179 0.179
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0029 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.0154 0.0192
Schistosoma mansoni biogenic amine receptor 0.0063 0.0154 0.0317
Brugia malayi larval opioid receptor 0.0063 0.0154 0.0154
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus alpha 1A adrenergic receptor 0.0063 0.0154 0.0192
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.0154 0.0192
Brugia malayi Protein set-1 0.0071 0.0198 0.0198
Trichomonas vaginalis cyclin B, putative 0.005 0.0082 0.0215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Echinococcus granulosus integrin alpha 3 0.0117 0.0449 0.056
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus g protein coupled receptor 0.0063 0.0154 0.0192
Echinococcus granulosus fmrfamide receptor 0.0063 0.0154 0.0192
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.005 0.0082 1
Schistosoma mansoni adenoreceptor 0.0063 0.0154 0.0317
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.004 0.0029 0.5
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.018 0.0788 0.2689
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.0154 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0154 0.0317
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.004 0.0029 0.5
Schistosoma mansoni hypothetical protein 0.0063 0.0154 0.0317
Toxoplasma gondii rhoptry neck protein RON9 0.0066 0.017 0.8456
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Trichomonas vaginalis WD repeat domain, putative 0.0305 0.1463 0.5054
Loa Loa (eye worm) hypothetical protein 0.0171 0.0739 0.0739
Toxoplasma gondii histone lysine methyltransferase SET8 0.0071 0.0198 1
Echinococcus multilocularis protein will die slowly 0.0305 0.1463 0.1829
Plasmodium falciparum apical sushi protein 0.0066 0.017 0.8456
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Brugia malayi Sushi domain 0.0066 0.017 0.017
Echinococcus multilocularis fmrfamide receptor 0.0063 0.0154 0.0192
Trichomonas vaginalis cyclins, putative 0.005 0.0082 0.0215
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Brugia malayi neuropeptide F receptor 0.0063 0.0154 0.0154
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.0154 0.0192
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.004 0.0029 0.0029
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.004 0.0029 0.5
Onchocerca volvulus 0.005 0.0082 0.0561
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.004 0.0029 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Onchocerca volvulus 0.0038 0.0021 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Schistosoma mansoni hypothetical protein 0.0369 0.1812 0.3734
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0171 0.0739 0.0739
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0063 0.0154 0.0154
Echinococcus multilocularis dro:myosuppressin receptor 0.0063 0.0154 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Echinococcus granulosus neuropeptide receptor A26 0.0063 0.0154 0.0192
Schistosoma mansoni hypothetical protein 0.0171 0.0739 0.1522
Onchocerca volvulus 0.0063 0.0154 0.1051
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.0154 0.0192
Mycobacterium leprae Possible secreted protease 0.004 0.0029 0.5
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Schistosoma mansoni hypothetical protein 0.018 0.0788 0.1625
Loa Loa (eye worm) proprotein convertase 2 0.022 0.1004 0.1004
Schistosoma mansoni myosin xvIII 0.0063 0.0154 0.0317
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Onchocerca volvulus 0.0066 0.017 0.1164
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0038 0.0021 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.0154 0.0317
Echinococcus multilocularis membrane bound transcription factor site 1 0.004 0.0029 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0029 0.003
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Onchocerca volvulus 0.0066 0.017 0.1164
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.0154 0.0317
Echinococcus multilocularis G protein coupled receptor 139 0.0827 0.4287 0.5357
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Trypanosoma cruzi cyclin, putative 0.005 0.0082 1
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0038 0.0021 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.0154 0.0192
Brugia malayi G protein-coupled receptor F59B2.13 0.0063 0.0154 0.0154
Echinococcus granulosus 7TM GPCR rhodopsin 0.0063 0.0154 0.0192
Schistosoma mansoni neuropeptide receptor 0.0063 0.0154 0.0317
Brugia malayi Dopamine receptor 0.0063 0.0154 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Echinococcus multilocularis somatostatin receptor 0.0063 0.0154 0.0192
Schistosoma mansoni alpha-1 adrenergic receptor 0.0063 0.0154 0.0317
Brugia malayi putative neuropeptide receptor 0.0063 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0235 0.1087 0.224
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0566 0.2875 0.3593
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.0154 0.0192
Onchocerca volvulus 0.0063 0.0154 0.1051
Plasmodium falciparum subtilisin-like protease 3 0.004 0.0029 0.0488
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0038 0.0021 0.0021
Onchocerca volvulus 0.0063 0.0154 0.1051
Onchocerca volvulus 0.0066 0.017 0.1164
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Schistosoma mansoni amine GPCR 0.0063 0.0154 0.0317
Onchocerca volvulus 0.0305 0.1463 1
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.022 0.1004 0.2069
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0063 0.0154 0.0317
Schistosoma mansoni histamine h1 receptor 0.0063 0.0154 0.0317
Onchocerca volvulus 0.0063 0.0154 0.1051
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1514 0.8002 1
Schistosoma mansoni hypothetical protein 0.0305 0.1463 0.3017
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Schistosoma mansoni histone-lysine n-methyltransferase seto7 0.0071 0.0198 0.0408
Brugia malayi Zona pellucida-like domain containing protein 0.0038 0.0021 0.0021
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.004 0.0029 0.5
Onchocerca volvulus 0.0038 0.0021 0.0141
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Onchocerca volvulus 0.0063 0.0154 0.1051
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0063 0.0154 0.0154
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0063 0.0154 0.0317
Trypanosoma cruzi CYC2-like cyclin, putative 0.005 0.0082 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0105 0.0382 0.0478
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.004 0.0029 0.006
Echinococcus granulosus neuropeptide FF receptor 2 0.0063 0.0154 0.0192
Plasmodium falciparum SET domain protein, putative 0.0071 0.0198 1
Onchocerca volvulus 0.0063 0.0154 0.1051
Schistosoma mansoni site-1 peptidase (S08 family) 0.004 0.0029 0.006
Loa Loa (eye worm) subtilase 0.004 0.0029 0.0029
Schistosoma mansoni cyclin B 0.005 0.0082 0.0169
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0154 0.0317
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0063 0.0154 0.0154
Plasmodium vivax subtilisin-like protease 1 0.004 0.0029 0.0488
Treponema pallidum hypothetical protein 0.0038 0.0021 0.5
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Echinococcus multilocularis neuropeptide receptor 0.0827 0.4287 0.5357
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Brugia malayi Cyclin, N-terminal domain containing protein 0.005 0.0082 0.0082
Loa Loa (eye worm) endoprotease bli-4 0.0931 0.4851 0.4851
Schistosoma mansoni hypothetical protein 0.0063 0.0154 0.0317
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0154 0.0317
Schistosoma mansoni integrin alpha-ps 0.0036 0.0007 0.0015
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0094 0.0324 0.0404
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Echinococcus granulosus cyclin B 0.005 0.0082 0.0103
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Echinococcus granulosus tachykinin peptides receptor 99D 0.0063 0.0154 0.0192
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0171 0.0739 0.0923
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0154 0.0192
Onchocerca volvulus 0.0063 0.0154 0.1051
Brugia malayi hypothetical protein 0.0066 0.017 0.017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Schistosoma mansoni hypothetical protein 0.0038 0.0021 0.0043
Loa Loa (eye worm) melatonin receptor type 1A 0.0063 0.0154 0.0154
Giardia lamblia Furin precursor putative serine protease 0.018 0.0788 0.4404
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Schistosoma mansoni c4b-binding protein beta chain 0.0066 0.017 0.0351
Brugia malayi sulfakinin receptor protein 0.0063 0.0154 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Schistosoma mansoni neuropeptide receptor 0.0063 0.0154 0.0317
Toxoplasma gondii subtilisin SUB7 0.004 0.0029 0.0488
Onchocerca volvulus 0.0066 0.017 0.1164
Echinococcus granulosus histone lysine n methyltransferase setd8 0.0071 0.0198 0.0247
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0171 0.0739 0.1522
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Brugia malayi G-protein coupled receptor 0.0063 0.0154 0.0154
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.004 0.0029 0.5
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0566 0.2875 1
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.0154 0.0192
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.0154 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Echinococcus multilocularis neuropeptide receptor A26 0.0063 0.0154 0.0192
Echinococcus multilocularis fmrfamide receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0084 0.0271 0.0271
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0038 0.0021 0.0026
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Brugia malayi Cyclin, N-terminal domain containing protein 0.005 0.0082 0.0082
Plasmodium vivax subtilisin-like serine protease, putative 0.004 0.0029 0.0488
Plasmodium falciparum subtilisin-like protease 1 0.004 0.0029 0.0488
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Toxoplasma gondii subtilisin SUB11 0.004 0.0029 0.0488
Schistosoma mansoni amine GPCR 0.0063 0.0154 0.0317
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.0154 0.0192
Trichomonas vaginalis cyclin B, putative 0.005 0.0082 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0029 0.003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0566 0.2875 1
Onchocerca volvulus 0.0038 0.0021 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Brugia malayi Dopamine receptor protein 1 0.0063 0.0154 0.0154
Plasmodium vivax SET domain protein, putative 0.0071 0.0198 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Onchocerca volvulus 0.0038 0.0021 0.0141
Echinococcus multilocularis neuropeptide FF receptor 2 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Brugia malayi Dopamine receptor protein 2 0.0063 0.0154 0.0154
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.0154 0.0192
Echinococcus multilocularis integrin alpha ps 0.0069 0.0185 0.0231
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Onchocerca volvulus 0.0063 0.0154 0.1051
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.004 0.0029 0.0037
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Brugia malayi pregnancy-associated plasma protein-A 0.0066 0.017 0.017
Onchocerca volvulus 0.0066 0.017 0.1164
Echinococcus granulosus neuropeptide receptor 0.0063 0.0154 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.022 0.1004 0.3443
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Onchocerca volvulus 0.0063 0.0154 0.1051
Onchocerca volvulus 0.0063 0.0154 0.1051
Trypanosoma brucei mitotic cyclin 6 0.005 0.0082 0.0499
Onchocerca volvulus 0.004 0.0029 0.02
Echinococcus granulosus sex peptide receptor 0.0063 0.0154 0.0192
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.022 0.1004 0.3443
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0105 0.0382 0.0382
Echinococcus granulosus voltage dependent calcium channel subunit 0.0038 0.0021 0.0026
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0063 0.0154 0.0192
Treponema pallidum 76K protein 0.0038 0.0021 0.5
Toxoplasma gondii rhoptry neck protein RON1 0.0066 0.017 0.8456
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.0154 0.0192
Brugia malayi RE15519p 0.0063 0.0154 0.0154
Toxoplasma gondii subtilisin SUB12 0.004 0.0029 0.0488
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0038 0.0021 0.0043
Schistosoma mansoni integrin alpha-ps 0.0069 0.0185 0.0381
Echinococcus granulosus g protein coupled receptor 0.0063 0.0154 0.0192
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.0154 0.0317
Echinococcus multilocularis G-protein coupled receptor, putative 0.0063 0.0154 0.0192
Schistosoma mansoni hypothetical protein 0.0038 0.0021 0.0043
Loa Loa (eye worm) hypothetical protein 0.0036 0.0007 0.0007
Onchocerca volvulus 0.0038 0.0021 0.0141
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Brugia malayi celfurPC protein 0.0751 0.3877 0.3877
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus somatostatin receptor 0.0063 0.0154 0.0192
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.004 0.0029 0.5
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0931 0.4851 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0029 0.0029
Schistosoma mansoni integrin alpha 0.0153 0.0642 0.1323
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Schistosoma mansoni biogenic amine receptor 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0063 0.0154 0.0192
Echinococcus multilocularis cyclin B 0.005 0.0082 0.0103
Loa Loa (eye worm) CUTiclin-Like family member 0.0038 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus orexin receptor type 2 0.0063 0.0154 0.0192
Loa Loa (eye worm) CUTiclin family member 0.0038 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0038 0.0021 0.0026
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.022 0.1004 0.3443
Echinococcus multilocularis integrin alpha 3 0.0117 0.0449 0.056
Brugia malayi hypothetical protein 0.0066 0.017 0.017
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0063 0.0154 0.0317
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0063 0.0154 0.0154
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0154 0.0192
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0154 0.0192
Onchocerca volvulus 0.0066 0.017 0.1164
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0116 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Echinococcus granulosus g-protein coupled receptor 0.0063 0.0154 0.0192
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0063 0.0154 0.0154
Schistosoma mansoni neuropeptide receptor 0.0827 0.4287 0.8836
Brugia malayi follicle stimulating hormone receptor 0.0063 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0171 0.0739 0.1522
Schistosoma mansoni hypothetical protein 0.0171 0.0739 0.1522
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.0154 0.0317
Brugia malayi Calcitonin receptor-like protein seb-1 0.054 0.2736 0.2736
Loa Loa (eye worm) hypothetical protein 0.012 0.0464 0.0464
Brugia malayi hypothetical protein 0.0038 0.0021 0.0021
Brugia malayi hypothetical protein 0.0066 0.017 0.017
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0063 0.0154 0.0317
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0063 0.0154 0.0317
Echinococcus multilocularis C type lectin domian containing protein 0.0066 0.017 0.0213
Brugia malayi Integrin alpha pat-2 precursor 0.0153 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.0154 0.0192
Echinococcus multilocularis integrin alpha ps 0.0069 0.0185 0.0231
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0063 0.0154 0.0192
Echinococcus multilocularis sex peptide receptor 0.0063 0.0154 0.0192
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus neuropeptide s receptor 0.0063 0.0154 0.0192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Echinococcus granulosus GPCR family 2 0.0171 0.0739 0.0923
Brugia malayi latrophilin 2 splice variant baaae 0.0369 0.1812 0.1812
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.0154 0.0154
Onchocerca volvulus 0.0038 0.0021 0.0141
Leishmania major cyclin 0.005 0.0082 1
Echinococcus granulosus neuroendocrine convertase 2 0.0585 0.2979 0.3723
Onchocerca volvulus 0.0063 0.0154 0.1051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Onchocerca volvulus 0.0038 0.0021 0.0141
Brugia malayi Zona pellucida-like domain containing protein 0.0038 0.0021 0.0021
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0066 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Echinococcus multilocularis serotonin receptor 0.0063 0.0154 0.0192
Toxoplasma gondii subtilisin SUB2 0.004 0.0029 0.0488
Echinococcus granulosus allatostatin A receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0063 0.0154 0.0154
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0063 0.0154 0.1051
Trichomonas vaginalis cyclin B, putative 0.005 0.0082 0.0215
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.004 0.0029 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0382 0.0788
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Brugia malayi Melatonin receptor type 1A 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Giardia lamblia High cysteine membrane protein Group 2 0.0346 0.1686 1
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.004 0.0029 0.5
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Trichomonas vaginalis cyclins, putative 0.005 0.0082 0.0215
Loa Loa (eye worm) WD40 repeat protein 0.0305 0.1463 0.1463
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Toxoplasma gondii subtilisin SUB8 0.004 0.0029 0.0488
Brugia malayi Subtilase family protein 0.004 0.0029 0.0029
Trichomonas vaginalis hypothetical protein 0.018 0.0788 0.2689
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0154 0.0192
Echinococcus granulosus C type lectin domian containing protein 0.0066 0.017 0.0213
Schistosoma mansoni hypothetical protein 0.0063 0.0154 0.0317
Plasmodium vivax apical sushi protein, putative 0.0066 0.017 0.8456
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.004 0.0029 0.0037
Brugia malayi endoprotease bli-4 precursor 0.0931 0.4851 0.4851
Loa Loa (eye worm) TYRA-2 protein 0.0063 0.0154 0.0154
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Echinococcus granulosus furin 0.0931 0.4851 0.6062
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus G protein coupled receptor 139 0.0063 0.0154 0.0192
Echinococcus granulosus membrane bound transcription factor site 1 0.004 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Schistosoma mansoni neuropeptide f receptor 76f 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0071 0.0198 0.0198
Brugia malayi Serotonin receptor 0.0063 0.0154 0.0154
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.0154 0.0192
Brugia malayi Immunoglobulin I-set domain containing protein 0.0038 0.0021 0.0021
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.0154 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Schistosoma mansoni furin-1 (S08 family) 0.0405 0.2005 0.4133
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.018 0.0788 0.2689
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.004 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Echinococcus granulosus 7tm_1 domain containing protein 0.0063 0.0154 0.0192
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0566 0.2875 0.3593
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0063 0.0154 0.0192
Brugia malayi G-protein coupled receptor 0.0063 0.0154 0.0154
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0063 0.0154 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Schistosoma mansoni opsin-like receptor 0.0063 0.0154 0.0317
Echinococcus granulosus peptide allatostatin:somatostatin 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Brugia malayi von Willebrand Factor 0.0038 0.0021 0.0021
Onchocerca volvulus 0.0063 0.0154 0.1051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Echinococcus granulosus collagen alpha 1VII chain 0.0038 0.0021 0.0026
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus serotonin receptor 0.0063 0.0154 0.0192
Brugia malayi GnHR receptor homolog 0.0063 0.0154 0.0154
Brugia malayi G protein-coupled receptor 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.018 0.0788 0.2689
Brugia malayi neuropeptide F receptor 0.0063 0.0154 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0382 0.0788
Echinococcus granulosus beta-adrenergic receptor kinase 0.0105 0.0382 0.0478
Echinococcus multilocularis c4b binding protein beta chain 0.0066 0.017 0.0213
Brugia malayi hypothetical protein 0.0066 0.017 0.017
Toxoplasma gondii subtilisin SUB4 0.004 0.0029 0.0488
Onchocerca volvulus 0.0063 0.0154 0.1051
Toxoplasma gondii subtilisin SUB9 0.004 0.0029 0.0488
Entamoeba histolytica cyclin, putative 0.005 0.0082 1
Echinococcus granulosus protein will die slowly 0.0305 0.1463 0.1829
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.022 0.1004 0.3443
Schistosoma mansoni opsin-like receptor 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.005 0.0082 0.0082
Trichomonas vaginalis cyclin B, putative 0.005 0.0082 0.0215
Schistosoma mansoni amine GPCR 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Echinococcus granulosus g protein coupled receptor 0.0063 0.0154 0.0192
Onchocerca volvulus Neuropeptide F receptor homolog 0.0063 0.0154 0.1051
Echinococcus multilocularis g-protein coupled receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0063 0.0154 0.0154
Echinococcus multilocularis 0.0751 0.3877 0.4845
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.0154 0.0192
Schistosoma mansoni opsin-like receptor 0.0063 0.0154 0.0317
Echinococcus multilocularis GPCR, family 2 0.0171 0.0739 0.0923
Trichomonas vaginalis cyclin A, putative 0.005 0.0082 0.0215
Toxoplasma gondii subtilisin SUB10 0.004 0.0029 0.0488
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.022 0.1004 0.3443
Echinococcus granulosus hypothetical protein 0.0063 0.0154 0.0192
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1514 0.8002 1
Onchocerca volvulus 0.0066 0.017 0.1164
Echinococcus granulosus integrin alpha ps 0.0069 0.0185 0.0231
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0063 0.0154 0.0192
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.0154 0.0317
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Brugia malayi ORL1-like opioid receptor 0.0063 0.0154 0.0154
Brugia malayi proprotein convertase 2 0.0585 0.2979 0.2979
Onchocerca volvulus 0.0066 0.017 0.1164
Echinococcus multilocularis allatostatin A receptor 0.0063 0.0154 0.0192
Toxoplasma gondii subtilisin SUB6 0.004 0.0029 0.0488
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Echinococcus multilocularis neuroendocrine convertase 2 0.0585 0.2979 0.3723
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0029 0.003
Echinococcus granulosus Furin 1 0.022 0.1004 0.1254
Echinococcus multilocularis serotonin receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) latrophilin receptor protein 2 0.0171 0.0739 0.0739
Echinococcus multilocularis Furin 1 0.022 0.1004 0.1254
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0788 0.2689
Onchocerca volvulus 0.0063 0.0154 0.1051
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Schistosoma mansoni biogenic amine receptor 0.0063 0.0154 0.0317
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.0154 0.0192
Schistosoma mansoni site-1 peptidase (S08 family) 0.004 0.0029 0.006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Onchocerca volvulus 0.0066 0.017 0.1164
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Brugia malayi Serotonin receptor 0.0063 0.0154 0.0154
Echinococcus multilocularis neuropeptide receptor 0.0063 0.0154 0.0192
Trypanosoma brucei RNA helicase, putative 0.0235 0.1087 1
Plasmodium vivax subtilisin-like protease 2, putative 0.004 0.0029 0.0488
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0063 0.0154 0.0192
Brugia malayi putative neuropeptide receptor NPR1 0.0063 0.0154 0.0154
Brugia malayi GCC2 and GCC3 family protein 0.0066 0.017 0.017
Schistosoma mansoni amine GPCR 0.0063 0.0154 0.0317
Loa Loa (eye worm) integrin alpha pat-2 0.0236 0.109 0.109
Brugia malayi hypothetical protein 0.0066 0.017 0.017
Brugia malayi AKH receptor 0.0063 0.0154 0.0154
Brugia malayi hypothetical protein 0.0066 0.017 0.017
Echinococcus granulosus G protein coupled receptor kinase 1 0.0094 0.0324 0.0404
Loa Loa (eye worm) hypothetical protein 0.0116 0.044 0.044
Echinococcus granulosus neuropeptide receptor 0.0827 0.4287 0.5357
Brugia malayi neuroendocrine convertase 1 precursor 0.0585 0.2979 0.2979
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0171 0.0739 0.0923
Loa Loa (eye worm) pigment dispersing factor receptor c 0.054 0.2736 0.2736
Toxoplasma gondii subtilisin SUB1 0.004 0.0029 0.0488
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0066 0.017 0.017
Schistosoma mansoni growth hormone secretagogue receptor 0.0063 0.0154 0.0317
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154
Echinococcus granulosus dro:myosuppressin receptor 0.0063 0.0154 0.0192
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.0154 0.0154
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.0154 0.0192
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.004 0.0029 0.006
Brugia malayi Latrophilin receptor protein 2 0.0171 0.0739 0.0739
Trypanosoma cruzi cyclin, putative 0.005 0.0082 1
Echinococcus multilocularis orexin receptor type 2 0.0063 0.0154 0.0192
Brugia malayi Tachykinin-like peptides receptor 99D 0.0063 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.1883 1 1
Brugia malayi hypothetical protein 0.0063 0.0154 0.0154
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.022 0.1004 0.3443
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0063 0.0154 0.0192
Loa Loa (eye worm) hypothetical protein 0.0038 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0931 0.4851 0.4851
Onchocerca volvulus 0.0063 0.0154 0.1051
Brugia malayi von Willebrand factor type A domain containing protein 0.0038 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0369 0.1812 0.1812
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0154 0.0317
Onchocerca volvulus 0.0063 0.0154 0.1051
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.004 0.0029 0.003
Echinococcus granulosus c4b binding protein beta chain 0.0066 0.017 0.0213
Toxoplasma gondii subtilisin SUB5 0.004 0.0029 0.0488
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0063 0.0154 0.0192
Schistosoma mansoni hypothetical protein 0.0063 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0063 0.0154 0.0154

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 40 nM Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cells ChEMBL. 19201190
IC50 (functional) > 1000 nM Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assay ChEMBL. 19201190

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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