Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0118 | 0.0438 | 0.0438 |
Onchocerca volvulus | 0.0066 | 0.0223 | 0.0833 | |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0118 | 0.0438 | 0.1247 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | protein dispatched 1 | 0.0098 | 0.0353 | 0.0353 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.053 | 0.2143 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0079 | 0.0275 | 0.0275 |
Schistosoma mansoni | myosin xvIII | 0.0118 | 0.0438 | 0.1247 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.007 | 0.0236 | 0.2043 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0086 | 0.0303 | 0.1412 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0118 | 0.0438 | 0.0438 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.0406 | 0.501 |
Trichomonas vaginalis | glutaminase, putative | 0.03 | 0.1191 | 0.2771 |
Schistosoma mansoni | neuropeptide receptor | 0.0118 | 0.0438 | 0.1247 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.005 | 0.0429 |
Brugia malayi | GnHR receptor homolog | 0.0118 | 0.0438 | 0.233 |
Brugia malayi | neuropeptide F receptor | 0.0118 | 0.0438 | 0.233 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0315 | 0.1251 | 0.356 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.007 | 0.0236 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Leishmania major | pteridine reductase 1 | 0.007 | 0.0236 | 0.2043 |
Echinococcus multilocularis | fmrfamide receptor | 0.0118 | 0.0438 | 0.0438 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.1028 | 0.4205 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0285 | 0.1129 | 0.1129 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0236 | 0.1102 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0066 | 0.0223 | 0.0223 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0467 | 0.1881 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | sulfakinin receptor protein | 0.0118 | 0.0438 | 0.233 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0254 | 0.0721 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0111 | 0.0406 | 0.1154 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0079 | 0.0275 | 0.0275 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.0035 | 0.0304 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.005 | 0.0429 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.0376 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0275 | 0.1281 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0118 | 0.0438 | 0.1247 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0043 | 0.0372 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.2043 |
Schistosoma mansoni | amine GPCR | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.0254 | 0.1183 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.005 | 0.0263 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0079 | 0.0275 | 0.0574 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.007 | 0.0236 | 0.0562 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Schistosoma mansoni | histamine h1 receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0765 | 0.2177 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0079 | 0.0275 | 0.0653 |
Schistosoma mansoni | neuropeptide receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | neuroligin | 0.0079 | 0.0275 | 0.0275 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.007 | 0.0236 | 0.0562 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | dihydropteridine reductase | 0.007 | 0.0236 | 0.0672 |
Onchocerca volvulus | 0.007 | 0.0236 | 0.0897 | |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.0254 | 0.1348 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0765 | 0.2177 |
Onchocerca volvulus | 0.0079 | 0.0275 | 0.1082 | |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0024 | 0.0111 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.2043 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0241 | 0.0684 |
Echinococcus granulosus | g-protein coupled receptor | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.029 | 0.0825 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0079 | 0.0275 | 0.0781 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Onchocerca volvulus | 0.0079 | 0.0275 | 0.1082 | |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0118 | 0.0438 | 0.0438 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0035 | 0.0027 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0079 | 0.0275 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0275 | 0.1281 |
Echinococcus multilocularis | sex peptide receptor | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0241 | 0.1123 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0138 | 0.052 | 0.4496 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0254 | 0.0721 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0118 | 0.0438 | 0.0438 |
Echinococcus granulosus | tar DNA binding protein | 0.0074 | 0.0254 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.005 | 0.0231 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0083 | 0.0237 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.005 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0383 | 0.1785 |
Trypanosoma brucei | pteridine reductase 1 | 0.007 | 0.0236 | 0.2043 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0138 | 0.052 | 0.4496 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0315 | 0.1251 | 0.1251 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0035 | 0.0094 | 0.0436 |
Brugia malayi | ORL1-like opioid receptor | 0.0118 | 0.0438 | 0.233 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0118 | 0.0438 | 0.0438 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0118 | 0.0438 | 0.233 |
Echinococcus granulosus | neuropeptide receptor | 0.0862 | 0.3515 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0079 | 0.0275 | 0.0781 |
Echinococcus multilocularis | g protein coupled receptor | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0467 | 0.1881 | 0.8777 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.005 | 0.0231 |
Loa Loa (eye worm) | glutaminase | 0.03 | 0.1191 | 0.5555 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Echinococcus granulosus | neuropeptide s receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | expressed conserved protein | 0.0188 | 0.0724 | 0.0724 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0118 | 0.1019 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Echinococcus granulosus | geminin | 0.0197 | 0.0765 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Leishmania major | oxidoreductase-like protein | 0.007 | 0.0236 | 0.2043 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0718 | 0.2923 | 0.8314 |
Schistosoma mansoni | biogenic amine receptor | 0.0118 | 0.0438 | 0.1247 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.007 | 0.0236 | 0.0482 |
Schistosoma mansoni | neuropeptide receptor | 0.0862 | 0.3515 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0718 | 0.2923 | 0.2923 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0223 | 0.0634 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.1028 | 0.4205 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0275 | 0.1281 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0292 | 0.1156 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.005 | 0.0118 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0315 | 0.1251 | 0.356 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.007 | 0.0236 | 0.0672 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.007 | 0.0236 | 0.0562 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.007 | 0.0236 | 0.0562 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0083 | 0.0443 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.0143 | 0.034 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0083 | 0.0237 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0254 | 0.0721 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0083 | 0.0237 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0118 | 0.0438 | 0.0438 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | geminin | 0.0197 | 0.0765 | 0.0765 |
Loa Loa (eye worm) | carboxylesterase | 0.0079 | 0.0275 | 0.1281 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.0043 | 0.0372 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.007 | 0.0236 | 0.2719 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Brugia malayi | glutaminase DH11.1 | 0.03 | 0.1191 | 0.6328 |
Schistosoma mansoni | P2X receptor subunit | 0.0315 | 0.1251 | 0.356 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0118 | 0.0438 | 0.233 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.0035 | 0.0084 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0118 | 0.0438 | 0.0438 |
Brugia malayi | Melatonin receptor type 1A | 0.0118 | 0.0438 | 0.233 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | biogenic amine receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0254 | 0.0721 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Brugia malayi | Cytochrome P450 family protein | 0.0035 | 0.0094 | 0.0497 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.005 | 0.0118 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.005 | 0.0118 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.002 | 0.0047 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0083 | 0.0083 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Mycobacterium ulcerans | glutaminase | 0.03 | 0.1191 | 0.2832 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0463 | 0.1865 | 0.8703 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Onchocerca volvulus | 0.0079 | 0.0275 | 0.1082 | |
Brugia malayi | Pre-SET motif family protein | 0.0066 | 0.0223 | 0.1185 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0118 | 0.0438 | 0.0438 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0079 | 0.0275 | 0.0781 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.0376 | 0.1999 |
Loa Loa (eye worm) | glutaminase 2 | 0.03 | 0.1191 | 0.5555 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.0562 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Loa Loa (eye worm) | carboxylesterase | 0.0079 | 0.0275 | 0.1281 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0118 | 0.1019 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0118 | 0.0438 | 0.0438 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0118 | 0.0438 | 0.233 |
Onchocerca volvulus | 0.0079 | 0.0275 | 0.1082 | |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0203 | 0.0787 | 0.224 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0118 | 0.1019 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0043 | 0.02 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0035 | 0.0164 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.0376 | 0.1755 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0024 | 0.0111 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | G protein-coupled receptor | 0.0118 | 0.0438 | 0.233 |
Loa Loa (eye worm) | hypothetical protein | 0.0467 | 0.1881 | 0.8777 |
Echinococcus multilocularis | serotonin receptor | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | amine GPCR | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0241 | 0.1279 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.0043 | 0.02 |
Echinococcus multilocularis | somatostatin receptor | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0111 | 0.0406 | 0.1154 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0275 | 0.1281 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0223 | 0.0634 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0118 | 0.0438 | 0.1247 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0079 | 0.0275 | 0.0574 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.0254 | 0.1183 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0083 | 0.0389 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.0406 | 0.1154 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.005 | 0.0118 |
Brugia malayi | Carboxylesterase family protein | 0.0079 | 0.0275 | 0.146 |
Brugia malayi | Carboxylesterase family protein | 0.0079 | 0.0275 | 0.146 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0376 | 0.1755 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.0775 | 0.3614 |
Schistosoma mansoni | neuropeptide receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0118 | 0.0438 | 0.2045 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | neuropeptide F receptor | 0.0118 | 0.0438 | 0.233 |
Echinococcus multilocularis | tar DNA binding protein | 0.0074 | 0.0254 | 0.0254 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.005 | 0.0118 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0079 | 0.0275 | 0.0653 |
Echinococcus multilocularis | protein patched | 0.0086 | 0.0303 | 0.0303 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0024 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0024 | 0.0111 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0118 | 0.0438 | 0.1869 |
Mycobacterium ulcerans | hypothetical protein | 0.0154 | 0.0584 | 0.139 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0064 | 0.0213 | 0.0605 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.1028 | 0.4205 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.1028 | 0.4205 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0275 | 0.1281 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0083 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Loa Loa (eye worm) | oxidoreductase | 0.007 | 0.0236 | 0.1102 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0118 | 0.0438 | 0.0438 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0083 | 0.0443 |
Echinococcus granulosus | g protein coupled receptor | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0024 | 0.0057 |
Schistosoma mansoni | glutaminase | 0.03 | 0.1191 | 0.3387 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0024 | 0.0111 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0285 | 0.1129 | 0.3213 |
Schistosoma mansoni | adenoreceptor | 0.0118 | 0.0438 | 0.1247 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.007 | 0.0236 | 0.2043 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.029 | 0.0825 |
Brugia malayi | Carboxylesterase family protein | 0.0467 | 0.1881 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.005 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0079 | 0.0275 | 0.0781 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.0035 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | Carboxylesterase family protein | 0.0467 | 0.1881 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.02 | 0.0775 | 0.2203 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.007 | 0.0236 | 0.0562 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0079 | 0.0275 | 0.0275 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.002 | 0.0047 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | opsin-like receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0066 | 0.0223 | 0.0634 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0035 | 0.0304 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.0043 | 0.0372 |
Schistosoma mansoni | acetylcholinesterase | 0.0079 | 0.0275 | 0.0781 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0118 | 0.0438 | 0.2045 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0118 | 0.0438 | 0.1247 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.005 | 0.0194 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | G-protein coupled receptor | 0.0118 | 0.0438 | 0.233 |
Loa Loa (eye worm) | hypothetical protein | 0.053 | 0.2143 | 1 |
Trypanosoma brucei | oxidoreductase-like protein | 0.007 | 0.0236 | 0.2043 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | g protein coupled receptor | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0275 | 0.1281 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus granulosus | fmrfamide receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.005 | 0.0118 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.007 | 0.0236 | 0.2043 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | follicle stimulating hormone receptor | 0.0118 | 0.0438 | 0.233 |
Brugia malayi | Serotonin receptor | 0.0118 | 0.0438 | 0.233 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0118 | 0.0438 | 0.0438 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0035 | 0.01 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0118 | 0.0438 | 0.0438 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0083 | 0.0237 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.0043 | 0.0102 |
Brugia malayi | Pre-SET motif family protein | 0.0463 | 0.1865 | 0.9915 |
Brugia malayi | hypothetical protein | 0.0111 | 0.0406 | 0.2156 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0066 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | Serotonin receptor | 0.0118 | 0.0438 | 0.233 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | neuroligin | 0.0079 | 0.0275 | 0.0781 |
Schistosoma mansoni | P2X receptor subunit | 0.0315 | 0.1251 | 0.356 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.007 | 0.0236 | 0.0562 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.005 | 0.0118 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0079 | 0.0275 | 0.0781 |
Echinococcus granulosus | allatostatin A receptor | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Echinococcus granulosus | g protein coupled receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0035 | 0.01 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.1028 | 0.4205 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0315 | 0.1251 | 0.356 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0118 | 0.0438 | 0.233 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.005 | 0.0263 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0083 | 0.0237 |
Echinococcus multilocularis | acetylcholinesterase | 0.0467 | 0.1881 | 0.1881 |
Echinococcus granulosus | acetylcholinesterase | 0.0467 | 0.1881 | 0.5352 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0083 | 0.0389 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0043 | 0.0228 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.2043 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.0254 | 0.1348 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.007 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.0254 | 0.1183 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0118 | 0.0438 | 0.233 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | carboxylesterase 5A | 0.0467 | 0.1881 | 0.5352 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0315 | 0.1251 | 0.1251 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0086 | 0.0303 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0079 | 0.0275 | 0.0653 |
Schistosoma mansoni | amine GPCR | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0035 | 0.01 |
Mycobacterium ulcerans | oxidoreductase | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | neuropeptide receptor | 0.0862 | 0.3515 | 0.3515 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0035 | 0.0187 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.002 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus granulosus | hypothetical protein | 0.0118 | 0.0438 | 0.1247 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.0406 | 0.501 |
Trichomonas vaginalis | set domain proteins, putative | 0.0527 | 0.213 | 0.5025 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.005 | 0.0231 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.1028 | 0.4205 | 1 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.1028 | 0.4205 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0118 | 0.0438 | 0.233 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0086 | 0.0303 | 0.0861 |
Brugia malayi | RE15519p | 0.0118 | 0.0438 | 0.233 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0066 | 0.0223 | 0.053 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | serotonin receptor | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0083 | 0.0237 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0086 | 0.0303 | 0.0642 |
Brugia malayi | Dopamine receptor | 0.0118 | 0.0438 | 0.233 |
Echinococcus multilocularis | g protein coupled receptor | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.005 | 0.0118 |
Echinococcus granulosus | sex peptide receptor | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.02 | 0.0775 | 0.4117 |
Schistosoma mansoni | hypothetical protein | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.0155 | 0.1341 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0315 | 0.1251 | 0.1251 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0111 | 0.0406 | 0.0406 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0079 | 0.0275 | 0.0653 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0862 | 0.3515 | 0.3515 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.005 | 0.0194 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0083 | 0.0083 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.1028 | 0.4205 | 1 |
Brugia malayi | RNA binding protein | 0.0074 | 0.0254 | 0.1348 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0467 | 0.1881 | 0.8777 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.007 | 0.0236 | 0.0672 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0066 | 0.0223 | 0.0634 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0086 | 0.0303 | 0.0861 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0303 | 0.1412 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.007 | 0.0236 | 0.0562 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.0406 | 0.501 |
Echinococcus multilocularis | neuropeptide receptor | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | serotonin receptor | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0079 | 0.0275 | 0.0781 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.0035 | 0.0084 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0118 | 0.1019 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | g protein coupled receptor | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.005 | 0.0118 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.0438 |
Echinococcus granulosus | expressed conserved protein | 0.0188 | 0.0724 | 0.2061 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.005 | 0.0429 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0035 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.005 | 0.0118 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0138 | 0.052 | 0.4496 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.1028 | 0.4205 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.007 | 0.0236 | 0.1256 |
Echinococcus multilocularis | allatostatin A receptor | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0043 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.007 | 0.0236 | 0.2043 |
Loa Loa (eye worm) | carboxylesterase | 0.0467 | 0.1881 | 0.8777 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | amine GPCR | 0.0118 | 0.0438 | 0.1247 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.005 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0118 | 0.0438 | 0.0438 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0035 | 0.0304 |
Schistosoma mansoni | gliotactin | 0.0079 | 0.0275 | 0.0781 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 0.1156 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.005 | 0.0118 |
Echinococcus granulosus | somatostatin receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0024 | 0.0111 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | fmrfamide receptor | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.029 | 0.0825 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0118 | 0.0438 | 0.1247 |
Onchocerca volvulus | 0.0079 | 0.0275 | 0.1082 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0118 | 0.0438 | 0.0438 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0035 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | hypothetical protein | 0.0079 | 0.0275 | 0.146 |
Brugia malayi | larval opioid receptor | 0.0118 | 0.0438 | 0.233 |
Schistosoma mansoni | patched 1 | 0.0086 | 0.0303 | 0.0861 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | AKH receptor | 0.0118 | 0.0438 | 0.233 |
Echinococcus multilocularis | acetylcholinesterase | 0.0467 | 0.1881 | 0.1881 |
Schistosoma mansoni | amine GPCR | 0.0278 | 0.1101 | 0.3132 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.0035 | 0.0084 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Brugia malayi | putative neuropeptide receptor | 0.0118 | 0.0438 | 0.233 |
Echinococcus granulosus | acetylcholinesterase | 0.0467 | 0.1881 | 0.5352 |
Brugia malayi | Dopamine receptor protein 1 | 0.0118 | 0.0438 | 0.233 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0275 | 0.1281 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0718 | 0.2923 | 0.8314 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.007 | 0.0236 | 0.0562 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0118 | 0.0438 | 0.1869 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0118 | 0.0438 | 0.0438 |
Schistosoma mansoni | biogenic amine receptor | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0118 | 0.0438 | 0.2045 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0315 | 0.1251 | 0.356 |
Plasmodium vivax | SET domain protein, putative | 0.0066 | 0.0223 | 0.0476 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.007 | 0.0236 | 0.1256 |
Brugia malayi | hypothetical protein | 0.0118 | 0.0438 | 0.233 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.007 | 0.0236 | 0.1102 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.02 | 0.0775 | 0.0775 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.0406 | 0.501 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Brugia malayi | Dopamine receptor protein 2 | 0.0118 | 0.0438 | 0.233 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0118 | 0.0438 | 0.233 |
Echinococcus granulosus | neuropeptide receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.007 | 0.0236 | 0.1102 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.007 | 0.0236 | 0.0508 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0467 | 0.1881 | 0.1881 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0118 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0118 | 0.0438 | 0.2045 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.029 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0223 | 0.104 |
Echinococcus granulosus | orexin receptor type 2 | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | hypothetical protein | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | Carboxylesterase family protein | 0.0079 | 0.0275 | 0.146 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0118 | 0.0438 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.02 | 0.0775 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0118 | 0.0438 | 0.0438 |
Onchocerca volvulus | 0.007 | 0.0236 | 0.0897 | |
Schistosoma mansoni | opsin-like receptor | 0.0118 | 0.0438 | 0.1247 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.007 | 0.0236 | 0.0508 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0118 | 0.0438 | 0.0438 |
Brugia malayi | CHE-14 protein | 0.0086 | 0.0303 | 0.1609 |
Schistosoma mansoni | hypothetical protein | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0079 | 0.0275 | 0.0781 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.007 | 0.0236 | 0.0562 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Brugia malayi | G-protein coupled receptor | 0.0118 | 0.0438 | 0.233 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | opsin-like receptor | 0.0118 | 0.0438 | 0.1247 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0118 | 0.0438 | 0.1247 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0118 | 0.0438 | 0.1247 |
Brugia malayi | Carboxylesterase family protein | 0.0079 | 0.0275 | 0.146 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0118 | 0.0438 | 0.1247 |
Onchocerca volvulus | 0.0527 | 0.213 | 1 | |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0043 | 0.0228 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.0043 | 0.0372 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0154 | 0.0584 | 0.139 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.002 | 0.0047 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Onchocerca volvulus | 0.0118 | 0.0438 | 0.1869 | |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0236 | 0.0562 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.0035 | 0.0304 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0118 | 0.0438 | 0.233 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0438 | 0.2045 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0254 | 0.0721 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0066 | 0.0223 | 0.0634 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0118 | 0.0438 | 0.1247 |
Schistosoma mansoni | P2X receptor subunit | 0.0315 | 0.1251 | 0.356 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 0.1156 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.007 | 0.0236 | 0.0562 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0292 | 0.1156 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0118 | 0.0438 | 0.1247 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 25 % | Calcemic effect in vivo in vitamin D-replete normal NMRI mice by daily intraperitoneal injections of compound and 1alpha,25 (OH)2D3 for 7 consecutive days | ChEMBL. | 12039579 |
Activity (functional) | = 1250 % | Percent inhibition against HL-60 cell line (50% dose response), relative to 1alpha,25 (OH)2D3 (100% activity) determined in vitro | ChEMBL. | 12039579 |
Activity (functional) | = 8000 % | Percent inhibition against MCF-7 cell line (50% dose response), relative to 1alpha,25 (OH)2D3 (100% activity) determined in vitro | ChEMBL. | 12039579 |
Relative affinity (binding) | = 75 | Displacement of 50% binding of [3H]alpha,25 (OH)2D3 from pig intestinal mucosa Vitamin D3 receptor | ChEMBL. | 12039579 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.