Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | guanylate cyclase, putative | 0.0048 | 0.042 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0031 | 0.0158 | 0.0099 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0158 | 0.0054 |
Brugia malayi | hypothetical protein | 0.0048 | 0.042 | 0.0456 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0224 | 0.4086 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0048 | 0.042 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0158 | 0.3767 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0224 | 0.5335 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.005 | 0.0444 | 0.0419 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.2389 | 0.2308 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Onchocerca volvulus | 0.0139 | 0.1771 | 0.3007 | |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0181 | 0.2389 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1531 | 0.2071 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0502 | 0.7146 | 1 |
Onchocerca volvulus | 0.0181 | 0.2389 | 0.4123 | |
Echinococcus granulosus | endoplasmin | 0.0026 | 0.0089 | 0.0063 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0089 | 0.2111 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0048 | 0.042 | 1 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0502 | 0.7146 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Schistosoma mansoni | apoptosis regulator bax | 0.0493 | 0.7019 | 0.6987 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0105 | 0.0011 |
Echinococcus granulosus | heat shock protein 90 | 0.0026 | 0.0089 | 0.0063 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0493 | 0.7019 | 0.7011 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0048 | 0.042 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0493 | 0.7019 | 0.6987 |
Echinococcus multilocularis | transcription factor btf3 | 0.0035 | 0.0224 | 0.0198 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0138 | 0.1747 | 0.1725 |
Brugia malayi | PAS domain containing protein | 0.0186 | 0.2465 | 0.3413 |
Leishmania major | protein kinase, putative | 0.0048 | 0.042 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0158 | 0.3767 |
Schistosoma mansoni | loxhd1 | 0.0181 | 0.2389 | 0.2308 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0694 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Onchocerca volvulus | 0.0181 | 0.2389 | 0.4123 | |
Echinococcus granulosus | geminin | 0.0171 | 0.2231 | 0.2211 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.005 | 0.0444 | 0.0419 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0493 | 0.7019 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Echinococcus granulosus | RUN | 0.0181 | 0.2389 | 0.2369 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0026 | 0.0089 | 0.5 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0035 | 0.0224 | 1 |
Leishmania major | basic transcription factor 3a, putative | 0.0035 | 0.0224 | 0.4086 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.2389 | 0.3311 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Schistosoma mansoni | single-minded | 0.0186 | 0.2465 | 0.2385 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Loa Loa (eye worm) | ICD-1 protein | 0.0035 | 0.0224 | 0.0183 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0048 | 0.042 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Brugia malayi | bHLH-PAS transcription factor | 0.0138 | 0.1747 | 0.2375 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0048 | 0.042 | 1 |
Brugia malayi | beta-NAC-like protein | 0.0035 | 0.0224 | 0.0173 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0181 | 0.2389 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0031 | 0.0158 | 0.0099 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Leishmania major | prostaglandin f synthase, putative | 0.0031 | 0.0158 | 0.2099 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.2979 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0493 | 0.7019 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0507 | 0.7224 | 0.7195 |
Echinococcus granulosus | heat shock protein 90 | 0.0033 | 0.0188 | 0.0162 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0502 | 0.7146 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0181 | 0.2389 | 0.2308 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Trichomonas vaginalis | heat shock protein, putative | 0.0033 | 0.0188 | 0.4461 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0089 | 0.2111 |
Loa Loa (eye worm) | doublecortin family protein | 0.0181 | 0.2389 | 0.3311 |
Schistosoma mansoni | hypothetical protein | 0.0493 | 0.7019 | 0.6987 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.0188 | 0.0083 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Echinococcus granulosus | single minded 2 | 0.0138 | 0.1747 | 0.1725 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0033 | 0.0188 | 0.2979 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Mycobacterium leprae | Possible regulatory protein | 0.0048 | 0.042 | 0.0553 |
Schistosoma mansoni | rab6-interacting | 0.0181 | 0.2389 | 0.2308 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0048 | 0.042 | 1 |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0158 | 0.7046 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0402 | 0.5668 | 0.5657 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0089 | 0.2111 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0105 | 0.0079 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.0188 | 0.0083 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0105 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.3231 | 0.4527 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0031 | 0.0158 | 0.2099 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0055 | 0.0519 | 0.5 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0188 | 0.2979 |
Echinococcus multilocularis | geminin | 0.0171 | 0.2231 | 0.2211 |
Echinococcus granulosus | lamin | 0.0027 | 0.0105 | 0.0079 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0033 | 0.0188 | 0.4428 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 0.3231 | 0.3213 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0048 | 0.042 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0158 | 0.3767 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0181 | 0.2389 | 0.2369 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0048 | 0.042 | 1 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Echinococcus multilocularis | RUN | 0.0181 | 0.2389 | 0.2369 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2231 | 0.2149 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Echinococcus multilocularis | endoplasmin | 0.0026 | 0.0089 | 0.0063 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0105 | 0.0079 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0422 | 0.0321 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.042 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0507 | 0.7224 | 0.7217 |
Schistosoma mansoni | polycystin 1-related | 0.0181 | 0.2389 | 0.2308 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0224 | 0.5335 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.4927 | 0.6977 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0105 | 0.0011 |
Treponema pallidum | heat shock protein 90 | 0.0026 | 0.0089 | 0.5 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0402 | 0.5668 | 0.5657 |
Brugia malayi | Endoplasmin precursor | 0.0033 | 0.0188 | 0.0119 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0031 | 0.0158 | 0.0185 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0105 | 0.0079 |
Schistosoma mansoni | transcription factor btf3 | 0.0035 | 0.0224 | 0.0121 |
Brugia malayi | hypothetical protein | 0.0181 | 0.2389 | 0.3303 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0181 | 0.2389 | 0.2369 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0422 | 0.0459 |
Brugia malayi | hypothetical protein | 0.0123 | 0.1531 | 0.2062 |
Mycobacterium leprae | PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) | 0.0502 | 0.7146 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0158 | 0.7046 |
Brugia malayi | hypothetical protein | 0.0181 | 0.2389 | 0.3303 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0493 | 0.7019 | 0.7011 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0502 | 0.7146 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0181 | 0.2389 | 0.2308 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0026 | 0.0089 | 0.0063 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.2389 | 0.3311 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0033 | 0.0188 | 0.4428 |
Loa Loa (eye worm) | hypothetical protein | 0.0493 | 0.7019 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0048 | 0.042 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0048 | 0.042 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.0188 | 0.0083 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0493 | 0.7019 | 0.7011 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0352 | 0.4927 | 0.6974 |
Echinococcus multilocularis | heat shock protein | 0.0033 | 0.0188 | 0.0162 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0224 | 1 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0035 | 0.0224 | 0.0167 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0031 | 0.0158 | 0.2099 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Leishmania major | aldo-keto reductase-like protein | 0.0031 | 0.0158 | 0.2099 |
Schistosoma mansoni | hypothetical protein | 0.0493 | 0.7019 | 0.6987 |
Trypanosoma cruzi | aldo-keto reductase | 0.0031 | 0.0158 | 0.2099 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Echinococcus granulosus | transcription factor btf3 | 0.0035 | 0.0224 | 0.0198 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0694 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0031 | 0.0158 | 0.0132 |
Schistosoma mansoni | pol-related | 0.0031 | 0.0158 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0401 | 0.5644 | 0.8014 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0105 | 0.0079 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus multilocularis | heat shock protein 90 | 0.0026 | 0.0089 | 0.0063 |
Brugia malayi | hypothetical protein | 0.0238 | 0.3231 | 0.4522 |
Echinococcus granulosus | heat shock protein | 0.0033 | 0.0188 | 0.0162 |
Toxoplasma gondii | NAC domain-containing protein | 0.0035 | 0.0224 | 1 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.0188 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0158 | 0.0088 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0224 | 0.4086 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.1531 | 0.2574 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2231 | 0.2149 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.005 | 0.0444 | 0.0501 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0035 | 0.0224 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Mycobacterium leprae | Isocitrate lyase | 0.0235 | 0.3192 | 0.4446 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 0.3231 | 0.3213 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0033 | 0.0188 | 0.013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0224 | 0.5335 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 0.495 | 0.7011 |
Brugia malayi | Doublecortin family protein | 0.0181 | 0.2389 | 0.3303 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0026 | 0.0089 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0422 | 0.0321 |
Onchocerca volvulus | 0.0049 | 0.0422 | 0.0573 | |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0033 | 0.0188 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0158 | 0.0054 |
Brugia malayi | heat shock protein 90 | 0.0033 | 0.0188 | 0.0119 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus multilocularis | heat shock protein 90 | 0.0033 | 0.0188 | 0.0162 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.054 | 0.7712 | 0.7688 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0188 | 0.2979 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Mycobacterium ulcerans | putative regulatory protein | 0.0138 | 0.1747 | 0.2349 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0188 | 0.2979 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.042 | 0.0466 |
Onchocerca volvulus | 0.0401 | 0.5644 | 1 | |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0502 | 0.7146 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.2099 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.1531 | 0.2574 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0493 | 0.7019 | 0.7011 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0507 | 0.7224 | 0.7217 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1531 | 0.2071 |
Loa Loa (eye worm) | endoplasmin | 0.0033 | 0.0188 | 0.013 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0493 | 0.7019 | 0.6987 |
Leishmania major | protein kinase, putative | 0.0048 | 0.042 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.042 | 1 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0035 | 0.0224 | 0.0939 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Plasmodium falciparum | heat shock protein 90 | 0.0033 | 0.0188 | 0.0785 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0105 | 0.0079 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = -1.2 % | Activation of human estrogen receptor alpha expressed in HEK293 cells at 10 uM by beta-galactosidase reporter gene assay relative to 3,17 beta-estradiol | ChEMBL. | 18517258 |
Activity (binding) | = 5.8 % | Activation of human estrogen receptor beta expressed in HEK293 cells at 10 uM beta-galactosidase reporter gene assay relative to 3,17-beta-estradiol | ChEMBL. | 18517258 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.