Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cathepsin b | 0.1921 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1921 | 1 | 1 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1037 | 0.3507 | 0.2691 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0711 | 0.1116 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0711 | 0.1116 | 0.1116 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Loa Loa (eye worm) | fibroinase | 0.1037 | 0.3507 | 0.2691 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1092 | 0.3909 | 0.3909 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1092 | 0.3909 | 0.3909 |
Giardia lamblia | Cathepsin B precursor | 0.0756 | 0.1441 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 0.1441 | 0.1441 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1037 | 0.3507 | 0.3507 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1921 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1092 | 0.3909 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0711 | 0.1116 | 0.3182 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1092 | 0.3909 | 0.3909 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0756 | 0.1441 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0756 | 0.1441 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Loa Loa (eye worm) | cathepsin B | 0.0756 | 0.1441 | 0.0366 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Toxoplasma gondii | cathepsin CPL | 0.1037 | 0.3507 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1037 | 0.3507 | 0.3507 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1037 | 0.3507 | 0.8368 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1037 | 0.3507 | 0.2691 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0711 | 0.1116 | 0.1116 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1037 | 0.3507 | 1 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Plasmodium vivax | vivapain-2 | 0.1037 | 0.3507 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1092 | 0.3909 | 0.3909 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0711 | 0.1116 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0711 | 0.1116 | 0.1116 |
Leishmania major | cathepsin L-like protease | 0.1092 | 0.3909 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1921 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1037 | 0.3507 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1037 | 0.3507 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1037 | 0.3507 | 0.3507 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0711 | 0.1116 | 0.1116 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1921 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Echinococcus granulosus | cathepsin b | 0.1921 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0711 | 0.1116 | 0.1116 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.1037 | 0.3507 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1921 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1037 | 0.3507 | 0.3507 |
Echinococcus granulosus | cathepsin l1 | 0.1037 | 0.3507 | 0.3507 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1037 | 0.3507 | 0.3507 |
Echinococcus multilocularis | cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1037 | 0.3507 | 0.2691 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0711 | 0.1116 | 0.1116 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0756 | 0.1441 | 0.411 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0756 | 0.1441 | 0.3687 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1921 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0766 | 0.1518 | 0.1518 |
Echinococcus multilocularis | cathepsin b | 0.1921 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1037 | 0.3507 | 0.3507 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1037 | 0.3507 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Echinococcus multilocularis | cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Onchocerca volvulus | Cathepsin L homolog | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1037 | 0.3507 | 0.3507 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1037 | 0.3507 | 0.2691 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1037 | 0.3507 | 0.2691 |
Leishmania major | cathepsin L-like protease | 0.1092 | 0.3909 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1921 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0756 | 0.1441 | 0.1441 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Plasmodium vivax | vivapain-2 | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.