Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1483 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1483 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1483 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1483 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1483 | 1 | 1 |
Onchocerca volvulus | 0.1483 | 1 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1483 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1 | 0.3182 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.1483 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.1483 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0978 | 0.2881 | 0.2881 |
Brugia malayi | Cathepsin L-like precursor | 0.1 | 0.3182 | 0.3182 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1483 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1483 | 1 | 1 |
Onchocerca volvulus | 0.1483 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1483 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1483 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0978 | 0.2881 | 0.2881 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1483 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1483 | 1 | 1 |
Onchocerca volvulus | 0.1483 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1 | 0.3182 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1 | 0.3182 | 0.0422 |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.1483 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0978 | 0.2881 | 0.2881 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1483 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1483 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0978 | 0.2881 | 0.2881 |
Onchocerca volvulus | Cathepsin L homolog | 0.1483 | 1 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.1483 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1483 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1483 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1483 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1483 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1 | 0.3182 | 0.0422 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1 | 0.3182 | 0.3182 |
Brugia malayi | cathepsin L-like precursor | 0.1 | 0.3182 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.1483 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1483 | 1 | 1 |
Onchocerca volvulus | 0.1483 | 1 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0978 | 0.2881 | 0.2881 |
Echinococcus multilocularis | cathepsin b | 0.0978 | 0.2881 | 0.2881 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1483 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0978 | 0.2881 | 0.2881 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1483 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1483 | 1 | 1 |
Onchocerca volvulus | 0.1483 | 1 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.1483 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1 | 0.3182 | 0.3182 |
Echinococcus granulosus | cathepsin b | 0.0978 | 0.2881 | 0.2881 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1 | 0.3182 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.1 | 0.3182 | 0.0422 |
Brugia malayi | Cathepsin L-like precursor | 0.1483 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1483 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1483 | 1 | 0.5 |
Onchocerca volvulus | 0.1483 | 1 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.1483 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1483 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1483 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1483 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1483 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0978 | 0.2881 | 0.2881 |
Onchocerca volvulus | 0.1483 | 1 | 1 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0978 | 0.2881 | 0.2881 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1 | 0.3182 | 0.3182 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.