Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.006 | 0.0071 | 0.0401 |
Schistosoma mansoni | smad | 0.0076 | 0.0135 | 0.0178 |
Brugia malayi | hypothetical protein | 0.0464 | 0.1667 | 0.1656 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0047 | 0.002 | 0.0012 |
Echinococcus granulosus | guanine nucleotide binding protein subunit | 0.0055 | 0.0053 | 0.008 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.008 | 0.0149 | 0.1948 |
Echinococcus granulosus | guanine nucleotide binding protein G protein | 0.0055 | 0.0053 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0293 | 0.028 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0102 | 0.0235 | 0.0222 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0179 | 0.0543 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0877 | 0.3301 | 0.4856 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0055 | 0.005 | 0.0037 |
Loa Loa (eye worm) | nuclear factor I | 0.0094 | 0.0206 | 0.0192 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0122 | 0.1413 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.1434 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.012 | 0.0156 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.0122 | 0.0221 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0337 | 0.1168 | 0.2346 |
Loa Loa (eye worm) | hypothetical protein | 0.0954 | 0.3603 | 0.3595 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0224 | 0.0719 | 0.1434 |
Schistosoma mansoni | tar DNA-binding protein | 0.0877 | 0.3301 | 0.4856 |
Trichomonas vaginalis | glutaminase, putative | 0.0294 | 0.0995 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0102 | 0.0235 | 0.0451 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.0158 | 0.0459 | 0.0446 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0161 | 0.0471 | 0.6475 |
Brugia malayi | Guanine nucleotide-binding protein alpha-12 subunit, putative | 0.0055 | 0.0053 | 0.0039 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0102 | 0.0235 | 0.0451 |
Echinococcus granulosus | guanine nucleotide binding protein subunit | 0.0055 | 0.0053 | 0.008 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0076 | 0.0135 | 0.0246 |
Schistosoma mansoni | hypothetical protein | 0.0344 | 0.1193 | 0.1742 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0047 | 0.002 | 0.0009 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0047 | 0.002 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0814 | 0.3051 | 0.4486 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0047 | 0.002 | 0.0009 |
Echinococcus granulosus | geminin | 0.0344 | 0.1193 | 0.2398 |
Schistosoma mansoni | regulator of G protein signaling | 0.0047 | 0.002 | 0.0009 |
Brugia malayi | GTP-binding regulatory protein alpha chain - starfish, putative | 0.0055 | 0.0053 | 0.0039 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.006 | 0.0071 | 0.0058 |
Echinococcus multilocularis | gtp binding protein (I) alpha 1subunit | 0.0055 | 0.0053 | 0.008 |
Schistosoma mansoni | GTP-binding protein alpha subunit | 0.0055 | 0.0053 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0135 | 0.0121 |
Schistosoma mansoni | trimeric G-protein alpha o subunit | 0.0055 | 0.0053 | 0.0058 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0161 | 0.0471 | 0.6445 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0047 | 0.002 | 0.0012 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0161 | 0.0471 | 0.6475 |
Loa Loa (eye worm) | guanine nucleotide-binding protein alpha-12 subunit | 0.0055 | 0.0053 | 0.0039 |
Schistosoma mansoni | kinase | 0.0052 | 0.0038 | 0.0036 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0047 | 0.002 | 0.0012 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.0235 | 0.2105 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0102 | 0.0235 | 0.3141 |
Brugia malayi | glutaminase DH11.1 | 0.0294 | 0.0995 | 0.0983 |
Schistosoma mansoni | Smad4 | 0.017 | 0.0506 | 0.0727 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0877 | 0.3301 | 0.3292 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.002 | 0.0006 |
Onchocerca volvulus | 0.0055 | 0.0053 | 0.0093 | |
Loa Loa (eye worm) | heterotrimeric G protein alpha subunit | 0.0055 | 0.0053 | 0.0039 |
Schistosoma mansoni | glutaminase | 0.0294 | 0.0995 | 0.145 |
Brugia malayi | hypothetical protein | 0.0047 | 0.002 | 0.0006 |
Echinococcus granulosus | expressed protein | 0.0055 | 0.0053 | 0.008 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0224 | 0.0719 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0076 | 0.0135 | 0.0246 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0122 | 0.0109 |
Onchocerca volvulus | 0.0055 | 0.0053 | 0.0093 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.2496 | 0.9699 | 0.9698 |
Brugia malayi | MH2 domain containing protein | 0.2496 | 0.9699 | 0.9698 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0123 | 0.0321 | 0.2996 |
Schistosoma mansoni | smad | 0.017 | 0.0506 | 0.0727 |
Brugia malayi | Guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0055 | 0.0053 | 0.0039 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.017 | 0.0506 | 0.0727 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0047 | 0.002 | 0.0012 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0047 | 0.002 | 0.0006 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.0235 | 0.2105 |
Brugia malayi | TAR-binding protein | 0.0877 | 0.3301 | 0.3292 |
Echinococcus multilocularis | guanine nucleotide binding protein subunit | 0.0055 | 0.0053 | 0.008 |
Echinococcus multilocularis | guanine nucleotide binding protein (G protein) | 0.0055 | 0.0053 | 0.008 |
Loa Loa (eye worm) | TAR-binding protein | 0.0877 | 0.3301 | 0.3292 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0102 | 0.0235 | 0.0327 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0053 | 0.0039 |
Schistosoma mansoni | Smad4 | 0.0076 | 0.0135 | 0.0178 |
Brugia malayi | hypothetical protein | 0.0047 | 0.002 | 0.0006 |
Onchocerca volvulus | 0.0464 | 0.1667 | 0.4598 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.0235 | 0.2105 |
Brugia malayi | hypothetical protein | 0.0161 | 0.0471 | 0.0457 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0116 | 0.0293 | 0.028 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0055 | 0.0053 | 0.0058 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0179 | 0.0543 | 0.5304 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0301 | 0.1023 | 0.1011 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.006 | 0.0071 | 0.0816 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.129 | 0.4933 | 0.4926 |
Trichomonas vaginalis | G protein (olf) alpha subunit, gnal, putative | 0.0055 | 0.0053 | 0.0212 |
Schistosoma mansoni | GTP-binding protein (I) alpha-1subunit gnai1 | 0.0055 | 0.0053 | 0.0058 |
Trichomonas vaginalis | GTP-binding protein (q) alpha-11 subunit, gna11, putative | 0.0055 | 0.0053 | 0.0212 |
Echinococcus multilocularis | tar DNA binding protein | 0.0877 | 0.3301 | 0.6683 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0053 | 0.0039 |
Schistosoma mansoni | smad1 5 8 and | 0.017 | 0.0506 | 0.0727 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0337 | 0.1168 | 0.2346 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.1667 | 0.1656 |
Echinococcus granulosus | smad | 0.017 | 0.0506 | 0.1001 |
Schistosoma mansoni | hypothetical protein | 0.0814 | 0.3051 | 0.4486 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0047 | 0.002 | 0.0006 |
Schistosoma mansoni | tar DNA-binding protein | 0.0877 | 0.3301 | 0.4856 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.0235 | 0.2105 |
Brugia malayi | G-protein alpha subunit | 0.0055 | 0.0053 | 0.0039 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.017 | 0.0506 | 0.1001 |
Loa Loa (eye worm) | glutaminase | 0.0294 | 0.0995 | 0.0983 |
Echinococcus granulosus | Smad4 | 0.017 | 0.0506 | 0.1001 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0055 | 0.0053 | 0.0212 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.0122 | 0.016 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0047 | 0.002 | 0.0006 |
Schistosoma mansoni | GTP-binding protein (q) alpha-11 subunit gna11 | 0.0055 | 0.0053 | 0.0058 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.006 | 0.0071 | 0.0401 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.017 | 0.0506 | 0.1001 |
Trichomonas vaginalis | GTP-binding protein (z) alpha subunit, gnaz, putative | 0.0055 | 0.0053 | 0.0212 |
Schistosoma mansoni | smad1 5 8 and | 0.017 | 0.0506 | 0.0727 |
Brugia malayi | Guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0055 | 0.0053 | 0.0039 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.0122 | 0.0221 |
Brugia malayi | Smad1 | 0.017 | 0.0506 | 0.0493 |
Echinococcus multilocularis | expressed protein | 0.0055 | 0.0053 | 0.008 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0102 | 0.0235 | 0.0602 |
Brugia malayi | hypothetical protein | 0.0104 | 0.0245 | 0.0232 |
Trichomonas vaginalis | GTP-binding protein (O) alpha subunit, gnao, putative | 0.0055 | 0.0053 | 0.0212 |
Schistosoma mansoni | hypothetical protein | 0.0814 | 0.3051 | 0.4486 |
Schistosoma mansoni | hypothetical protein | 0.0814 | 0.3051 | 0.4486 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0102 | 0.0235 | 0.0222 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.006 | 0.0071 | 0.0401 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0224 | 0.0719 | 1 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0116 | 0.0293 | 0.0569 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.2572 | 1 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.0706 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0122 | 0.016 |
Mycobacterium ulcerans | glutaminase | 0.0294 | 0.0995 | 0.5 |
Echinococcus multilocularis | geminin | 0.0344 | 0.1193 | 0.2398 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0055 | 0.0053 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0053 | 0.0039 |
Loa Loa (eye worm) | Smad1 | 0.017 | 0.0506 | 0.0493 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0053 | 0.0039 |
Echinococcus granulosus | tar DNA binding protein | 0.0877 | 0.3301 | 0.6683 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0179 | 0.0543 | 0.7505 |
Brugia malayi | MH2 domain containing protein | 0.017 | 0.0506 | 0.0493 |
Brugia malayi | guanine nucleotide-binding protein alpha-7 subunit, putative | 0.0055 | 0.0053 | 0.0039 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0076 | 0.0135 | 0.0121 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0161 | 0.0471 | 0.6475 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0055 | 0.0053 | 0.0058 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0122 | 0.1413 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.006 | 0.0071 | 0.0372 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.006 | 0.0071 | 0.0372 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0055 | 0.005 | 0.0519 |
Schistosoma mansoni | GTP-binding protein alpha subunit | 0.0055 | 0.0053 | 0.0058 |
Echinococcus multilocularis | guanine nucleotide binding protein subunit | 0.0055 | 0.0053 | 0.008 |
Echinococcus multilocularis | guanine nucleotide binding protein (G protein) | 0.0055 | 0.0053 | 0.008 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.129 | 0.4933 | 0.4926 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0224 | 0.0719 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0814 | 0.3051 | 0.6174 |
Schistosoma mansoni | Smad4 | 0.0076 | 0.0135 | 0.0178 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0076 | 0.0135 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0053 | 0.0039 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0814 | 0.3051 | 0.6174 |
Brugia malayi | guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0055 | 0.0053 | 0.0039 |
Loa Loa (eye worm) | glutaminase 2 | 0.0294 | 0.0995 | 0.0983 |
Loa Loa (eye worm) | guanine nucleotide-binding protein alpha-6 subunit | 0.0055 | 0.0053 | 0.0039 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0814 | 0.3051 | 0.3041 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0224 | 0.0719 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.1434 |
Loa Loa (eye worm) | RNA binding protein | 0.0877 | 0.3301 | 0.3292 |
Brugia malayi | MH1 domain containing protein | 0.017 | 0.0506 | 0.0493 |
Brugia malayi | Isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.0706 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0055 | 0.0053 | 0.0212 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.129 | 0.4933 | 0.7266 |
Loa Loa (eye worm) | hypothetical protein | 0.2572 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0179 | 0.0543 | 0.7505 |
Brugia malayi | RNA binding protein | 0.0877 | 0.3301 | 0.3292 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.129 | 0.4933 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.129 | 0.4933 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.0706 |
Entamoeba histolytica | hypothetical protein | 0.0143 | 0.0398 | 0.7045 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.129 | 0.4933 | 0.7266 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0055 | 0.0053 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.0471 | 0.0457 |
Schistosoma mansoni | hypothetical protein | 0.0344 | 0.1193 | 0.1742 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0814 | 0.3051 | 0.6174 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.2496 | 0.9699 | 0.9698 |
Schistosoma mansoni | smad1 5 8 and | 0.017 | 0.0506 | 0.0727 |
Schistosoma mansoni | dishevelled | 0.0047 | 0.002 | 0.0009 |
Brugia malayi | MH1 domain containing protein | 0.0094 | 0.0206 | 0.0192 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.1434 |
Schistosoma mansoni | GTP-binding protein alpha subunit gna | 0.0055 | 0.0053 | 0.0058 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0877 | 0.3301 | 0.3292 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.0235 | 0.2105 |
Schistosoma mansoni | tar DNA-binding protein | 0.0877 | 0.3301 | 0.4856 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0076 | 0.0135 | 0.0121 |
Brugia malayi | guanine nucleotide-binding protein G-o protein alpha subunit | 0.0055 | 0.0053 | 0.0039 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.1042 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0047 | 0.002 | 0.0012 |
Brugia malayi | N-terminal motif family protein | 0.0954 | 0.3603 | 0.3595 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0814 | 0.3051 | 0.3041 |
Schistosoma mansoni | GTP-binding protein (I) alpha subunit gnai | 0.0055 | 0.0053 | 0.0058 |
Echinococcus granulosus | guanine nucleotide binding protein G protein | 0.0055 | 0.0053 | 0.008 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.129 | 0.4933 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0084 | 0.007 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.0235 | 0.2105 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0047 | 0.002 | 0.0006 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.017 | 0.0506 | 0.1001 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0224 | 0.0719 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0047 | 0.002 | 0.0012 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0224 | 0.0719 | 1 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0179 | 0.0543 | 0.5304 |
Schistosoma mansoni | dishevelled | 0.0047 | 0.002 | 0.0009 |
Schistosoma mansoni | GTP-binding protein (q) alpha-11 subunit gna11 | 0.0055 | 0.0053 | 0.0058 |
Schistosoma mansoni | GTP-binding protein alpha subunit gna | 0.0055 | 0.0053 | 0.0058 |
Schistosoma mansoni | GTP-binding protein (I) alpha-1subunit gnai1 | 0.0055 | 0.0053 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.1758 | 0.6783 | 0.6779 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.1758 | 0.6783 | 0.6779 |
Giardia lamblia | Kinase, PLK | 0.0102 | 0.0235 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0072 | 0.012 | 0.0215 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0954 | 0.3603 | 1 |
Echinococcus multilocularis | Smad4 | 0.017 | 0.0506 | 0.1001 |
Echinococcus granulosus | gtp binding protein I alpha 1subunit | 0.0055 | 0.0053 | 0.008 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0224 | 0.0719 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0076 | 0.0135 | 0.0246 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0143 | 0.0398 | 0.7045 |
Trypanosoma brucei | polo-like protein kinase | 0.0102 | 0.0235 | 0.3141 |
Schistosoma mansoni | tar DNA-binding protein | 0.0877 | 0.3301 | 0.4856 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.006 | 0.0071 | 0.0816 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0087 | 0.0176 | 0.7493 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.0235 | 0.2105 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.002 | 0.0006 |
Leishmania major | hypothetical protein, conserved | 0.0161 | 0.0471 | 0.6475 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0814 | 0.3051 | 0.6174 |
Schistosoma mansoni | dep domain containing protein | 0.0047 | 0.002 | 0.0009 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0814 | 0.3051 | 0.6174 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.017 | 0.0506 | 0.0493 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0224 | 0.0719 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0224 | 0.0719 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0122 | 0.1413 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.006 | 0.0071 | 0.0085 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.2572 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0814 | 0.3051 | 0.6174 |
Brugia malayi | guanine nucleotide-binding protein G(o), alpha subunit, putative | 0.0055 | 0.0053 | 0.0039 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0123 | 0.0321 | 0.2996 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0122 | 0.1413 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0072 | 0.012 | 0.0215 |
Echinococcus multilocularis | smad | 0.017 | 0.0506 | 0.1001 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0224 | 0.0719 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.1434 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0047 | 0.002 | 0.0012 |
Brugia malayi | MH2 domain containing protein | 0.017 | 0.0506 | 0.0493 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0174 | 0.0522 | 0.9572 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0179 | 0.0543 | 0.053 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.017 | 0.0506 | 0.0493 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.017 | 0.0506 | 0.1001 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0206 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.002 | 0.0006 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0224 | 0.0719 | 0.1434 |
Brugia malayi | MH2 domain containing protein | 0.0076 | 0.0135 | 0.0121 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0047 | 0.002 | 0.0012 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.129 | 0.4933 | 1 |
Loa Loa (eye worm) | G protein alpha subunit 3 | 0.0055 | 0.0053 | 0.0039 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.129 | 0.4933 | 0.7266 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0047 | 0.002 | 0.0006 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0814 | 0.3051 | 0.3041 |
Brugia malayi | Guanine nucleotide-binding protein alpha-6 subunit, putative | 0.0055 | 0.0053 | 0.0039 |
Loa Loa (eye worm) | GTP-binding regulatory protein alpha chain | 0.0055 | 0.0053 | 0.0039 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0102 | 0.0235 | 0.3141 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0179 | 0.0543 | 0.5304 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0053 | 0.0039 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0102 | 0.0235 | 0.3718 |
Brugia malayi | MH1 domain containing protein | 0.017 | 0.0506 | 0.0493 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0076 | 0.0135 | 0.0246 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0102 | 0.0235 | 0.3141 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0076 | 0.0135 | 0.0321 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0337 | 0.1168 | 0.1705 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0047 | 0.002 | 0.0012 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0116 | 0.0293 | 0.0569 |
Schistosoma mansoni | hypothetical protein | 0.1758 | 0.6783 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0814 | 0.3051 | 0.3041 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0055 | 0.0053 | 0.0212 |
Brugia malayi | MH1 domain containing protein | 0.0094 | 0.0206 | 0.0192 |
Onchocerca volvulus | 0.0055 | 0.0053 | 0.0093 | |
Brugia malayi | DIX domain containing protein | 0.0047 | 0.002 | 0.0006 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.