Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glutamate receptor 1 | 0.0347 | 0.0389 | 0.0175 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0413 | 0.0799 | 0.0799 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.032 | 0.0219 | 0.0219 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.032 | 0.0219 | 0.0219 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0638 | 0.2199 | 0.2199 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.051 | 0.14 | 0.14 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0413 | 0.0799 | 0.0799 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0347 | 0.0389 | 0.0175 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0413 | 0.0799 | 0.0799 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0413 | 0.0799 | 0.0799 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0347 | 0.0389 | 0.0175 |
Brugia malayi | Carboxylesterase family protein | 0.1893 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1893 | 1 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0663 | 0.2353 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0347 | 0.0389 | 0.0175 |
Echinococcus multilocularis | acetylcholinesterase | 0.1893 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1893 | 1 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0347 | 0.0389 | 0.0175 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.032 | 0.0219 | 0.5 |
Echinococcus granulosus | neuroligin | 0.032 | 0.0219 | 0.0219 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0638 | 0.2199 | 0.2199 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.032 | 0.0219 | 0.0219 |
Echinococcus granulosus | acetylcholinesterase | 0.1893 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.032 | 0.0219 | 0.0219 |
Schistosoma mansoni | glutamate receptor kainate | 0.0347 | 0.0389 | 0.0175 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0413 | 0.0799 | 0.0799 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0923 | 0.3969 | 0.3834 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0946 | 0.4111 | 0.3979 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0347 | 0.0389 | 0.0175 |
Onchocerca volvulus | 0.032 | 0.0219 | 0.5 | |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0576 | 0.1809 | 0.1809 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0347 | 0.0389 | 0.0389 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.032 | 0.0219 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.032 | 0.0219 | 0.0219 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0413 | 0.0799 | 0.0799 |
Loa Loa (eye worm) | carboxylesterase | 0.1893 | 1 | 1 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0347 | 0.0389 | 0.0175 |
Echinococcus granulosus | acetylcholinesterase | 0.1893 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1893 | 1 | 1 |
Onchocerca volvulus | 0.032 | 0.0219 | 0.5 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.032 | 0.0219 | 0.0219 |
Echinococcus granulosus | carboxylesterase 5A | 0.1893 | 1 | 1 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0946 | 0.4111 | 0.4111 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1893 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0413 | 0.0799 | 0.0799 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0347 | 0.0389 | 0.0175 |
Echinococcus granulosus | glutamate receptor 2 | 0.0413 | 0.0799 | 0.0799 |
Echinococcus multilocularis | acetylcholinesterase | 0.1893 | 1 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0616 | 0.2063 | 1 |
Echinococcus granulosus | glutamate receptor NMDA | 0.051 | 0.14 | 0.14 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0347 | 0.0389 | 0.0175 |
Echinococcus multilocularis | neuroligin | 0.032 | 0.0219 | 0.0219 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0576 | 0.1809 | 0.1809 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0413 | 0.0799 | 0.0799 |
Onchocerca volvulus | 0.032 | 0.0219 | 0.5 | |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0663 | 0.2353 | 1 |
Onchocerca volvulus | 0.032 | 0.0219 | 0.5 | |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0946 | 0.4111 | 0.4111 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0413 | 0.0799 | 0.0799 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1893 | 1 | 1 |
Onchocerca volvulus | 0.032 | 0.0219 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.