Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.2652 | 0.5 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.2652 | 0.2652 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.2652 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.6161 | 0.4775 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0046 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.2652 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | dna polymerase eta | 0.0046 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.2652 | 0.2652 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.2652 | 0.5 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0046 | 1 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0032 | 0.6161 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.6161 | 0.4775 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.2652 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.2652 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.2652 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.2652 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.2652 | 0.1904 |
Trypanosoma brucei | unspecified product | 0.002 | 0.2652 | 0.1904 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.2652 | 0.2652 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.2652 | 0.2652 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.2652 | 0.5 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.2652 | 0.2652 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.2652 | 0.2652 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Echinococcus granulosus | dna polymerase eta | 0.0046 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.2652 | 0.2652 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.2652 | 0.2652 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.2652 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.2652 | 0.1904 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.