Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | Starlite/ChEMBL | References |
Homo sapiens | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | Peroxidase homolog | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | Peroxidasin homolog | 0.0063 | 0.2773 | 0.2773 |
Brugia malayi | Peroxidasin | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | Peroxidase homolog | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | 0.0063 | 0.2773 | 0.2773 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | 0.0063 | 0.2773 | 0.2773 | |
Onchocerca volvulus | Peroxidasin homolog | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Schistosoma mansoni | peroxidasin | 0.0063 | 0.2773 | 0.2773 |
Echinococcus granulosus | peroxidasin | 0.0063 | 0.2773 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | 0.0165 | 1 | 1 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0063 | 0.2773 | 0.2773 |
Brugia malayi | Animal haem peroxidase family protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | 0.0063 | 0.2773 | 0.2773 | |
Brugia malayi | Blistered cuticle protein 3 | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0063 | 0.2773 | 0.2773 |
Echinococcus multilocularis | peroxidasin | 0.0063 | 0.2773 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0063 | 0.2773 | 0.2773 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | 0.0165 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.9187 | 0.9187 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 1 | 1 |
Onchocerca volvulus | 0.0165 | 1 | 1 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0063 | 0.2773 | 0.2773 |
Brugia malayi | Animal haem peroxidase family protein | 0.0063 | 0.2773 | 0.2773 |
Onchocerca volvulus | Dual oxidase homolog | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Brugia malayi | Animal haem peroxidase family protein | 0.0063 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.2773 | 0.2773 |
Schistosoma mansoni | peroxidasin | 0.0063 | 0.2773 | 0.2773 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0165 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.