Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine proteinase, putative | 0.0711 | 0.1116 | 0.3182 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Leishmania major | cathepsin L-like protease | 0.1092 | 0.3909 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1921 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Loa Loa (eye worm) | cathepsin B | 0.0756 | 0.1441 | 0.0366 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1037 | 0.3507 | 0.3507 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1037 | 0.3507 | 0.8368 |
Toxoplasma gondii | cathepsin CPL | 0.1037 | 0.3507 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0756 | 0.1441 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0756 | 0.1441 | 0.5 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1092 | 0.3909 | 0.3909 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1921 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.1921 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1092 | 0.3909 | 0.3909 |
Giardia lamblia | Cathepsin B precursor | 0.0756 | 0.1441 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1037 | 0.3507 | 0.3507 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 0.1441 | 0.1441 |
Brugia malayi | Cathepsin L-like precursor | 0.0711 | 0.1116 | 0.1116 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Loa Loa (eye worm) | fibroinase | 0.1037 | 0.3507 | 0.2691 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1092 | 0.3909 | 0.3909 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0711 | 0.1116 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.1037 | 0.3507 | 0.2691 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1037 | 0.3507 | 1 |
Echinococcus granulosus | cathepsin b | 0.1921 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0711 | 0.1116 | 0.1116 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1921 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Echinococcus multilocularis | cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1037 | 0.3507 | 0.3507 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1037 | 0.3507 | 0.3507 |
Echinococcus granulosus | cathepsin l1 | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.1037 | 0.3507 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1921 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1092 | 0.3909 | 0.3909 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0711 | 0.1116 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0711 | 0.1116 | 0.1116 |
Plasmodium vivax | vivapain-2 | 0.1037 | 0.3507 | 1 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0711 | 0.1116 | 0.1116 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1037 | 0.3507 | 0.2691 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1037 | 0.3507 | 0.3507 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0711 | 0.1116 | 0.1116 |
Entamoeba histolytica | cysteine protease, putative | 0.1037 | 0.3507 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1037 | 0.3507 | 1 |
Leishmania major | cathepsin L-like protease | 0.1092 | 0.3909 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1921 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0756 | 0.1441 | 0.411 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0711 | 0.1116 | 0.1116 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0756 | 0.1441 | 0.3687 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1092 | 0.3909 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1037 | 0.3507 | 0.2691 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Onchocerca volvulus | 0.1037 | 0.3507 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1037 | 0.3507 | 0.2691 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1037 | 0.3507 | 0.3507 |
Plasmodium vivax | vivapain-2 | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1921 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0756 | 0.1441 | 0.1441 |
Leishmania major | cathepsin L-like protease | 0.1092 | 0.3909 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1037 | 0.3507 | 0.2691 |
Echinococcus multilocularis | cathepsin b | 0.1921 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1037 | 0.3507 | 0.8368 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1037 | 0.3507 | 0.3507 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0766 | 0.1518 | 0.1518 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1921 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1037 | 0.3507 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1037 | 0.3507 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1037 | 0.3507 | 0.3507 |
Echinococcus multilocularis | cysteine protease | 0.1037 | 0.3507 | 0.3507 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1037 | 0.3507 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1037 | 0.3507 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.