Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | cytoplasmic intermediate filament protein | 0.0043 | 0.0139 | 0.0328 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0075 | 0.0854 | 0.0872 |
Echinococcus multilocularis | musashi | 0.0081 | 0.0992 | 0.102 |
Plasmodium vivax | hypothetical protein, conserved | 0.0075 | 0.0854 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0043 | 0.0121 | 0.0059 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0043 | 0.0121 | 0.0095 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0043 | 0.0121 | 0.0095 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0211 | 0.0916 |
Brugia malayi | beta-lactamase family protein | 0.0075 | 0.0854 | 0.3524 |
Brugia malayi | intermediate filament protein | 0.0081 | 0.0992 | 0.4141 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0103 | 0.1495 | 0.6498 |
Schistosoma mansoni | thyroid hormone receptor | 0.045 | 0.9354 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0043 | 0.0121 | 0.0491 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0075 | 0.0854 | 0.3686 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0043 | 0.0121 | 0.0095 |
Onchocerca volvulus | 0.0075 | 0.0854 | 0.8414 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0043 | 0.0121 | 0.0085 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0075 | 0.0854 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.013 | 0.2106 | 0.9148 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0075 | 0.0852 | 0.3702 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0103 | 0.1495 | 0.6498 |
Brugia malayi | beta-lactamase | 0.0075 | 0.0854 | 0.3524 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0103 | 0.1495 | 0.6498 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.011 | 0.1658 | 0.7204 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0083 | 0.1035 | 0.4499 |
Schistosoma mansoni | lamin | 0.0081 | 0.0992 | 0.0997 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.013 | 0.2106 | 0.9148 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0854 | 0.3686 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0487 | 0.2088 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0066 | 0.0251 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0139 | 0.2301 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0043 | 0.0121 | 0.0491 |
Echinococcus granulosus | lamin | 0.0081 | 0.0992 | 0.1138 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0043 | 0.0121 | 0.0246 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0043 | 0.0121 | 0.0491 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0211 | 0.0916 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0075 | 0.0854 | 0.3709 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0059 | 0.0487 | 0.1884 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0043 | 0.0121 | 0.0246 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0043 | 0.0121 | 0.0246 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.009 | 0.1198 | 0.5205 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0043 | 0.0121 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Brugia malayi | nuclear receptor NHR-88 | 0.0043 | 0.0121 | 0.0246 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.011 | 0.1658 | 0.7204 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.011 | 0.1658 | 0.7204 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0043 | 0.0121 | 0.0491 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0047 | 0.0211 | 0.0181 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0043 | 0.0121 | 0.0246 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0139 | 0.2301 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0043 | 0.0121 | 0.0085 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0043 | 0.0121 | 0.0491 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0043 | 0.0121 | 0.0246 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0043 | 0.0121 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0043 | 0.0121 | 0.0059 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0107 | 0.159 | 0.1641 |
Giardia lamblia | GTOR | 0.0139 | 0.2301 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0075 | 0.0852 | 0.3702 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0043 | 0.0121 | 0.0059 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0211 | 0.0916 |
Echinococcus granulosus | lamin dm0 | 0.0081 | 0.0992 | 0.1138 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0043 | 0.0121 | 0.0059 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0075 | 0.0854 | 0.3713 |
Leishmania major | hypothetical protein, conserved | 0.0075 | 0.0854 | 0.3075 |
Brugia malayi | ecdysteroid receptor | 0.0043 | 0.0121 | 0.0246 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.011 | 0.1658 | 0.7204 |
Mycobacterium leprae | Probable lipase LipE | 0.0075 | 0.0854 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0043 | 0.0121 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0075 | 0.0854 | 0.3713 |
Loa Loa (eye worm) | beta-lactamase | 0.0075 | 0.0854 | 0.3686 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0042 | 0.0146 |
Brugia malayi | steroid hormone receptor | 0.0043 | 0.0121 | 0.0246 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0082 | 0.1017 | 0.4418 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0103 | 0.1495 | 0.6498 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0139 | 0.2301 | 1 |
Echinococcus multilocularis | lamin | 0.0081 | 0.0992 | 0.102 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0139 | 0.2301 | 0.2406 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0043 | 0.0121 | 0.0095 |
Schistosoma mansoni | lamin | 0.0081 | 0.0992 | 0.0997 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0043 | 0.0121 | 0.0059 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.045 | 0.9354 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0075 | 0.0854 | 0.3709 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0043 | 0.0121 | 0.0491 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0211 | 0.0883 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0075 | 0.0854 | 0.3075 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0043 | 0.0121 | 0.0246 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0107 | 0.159 | 0.1663 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0103 | 0.1495 | 1 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0047 | 0.0211 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0075 | 0.0854 | 0.0848 |
Brugia malayi | nuclear hormone receptor | 0.0043 | 0.0121 | 0.0246 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0075 | 0.0854 | 0.0848 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0043 | 0.0121 | 0.0095 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0075 | 0.0854 | 0.3709 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0075 | 0.0854 | 0.3713 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0854 | 0.3686 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0854 | 0.3686 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0075 | 0.0854 | 0.3709 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0075 | 0.0854 | 0.3075 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0408 | 0.8389 | 0.8964 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0103 | 0.1495 | 0.6498 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0083 | 0.1035 | 0.4499 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0059 | 0.0487 | 0.1884 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0082 | 0.1017 | 0.4418 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.159 | 0.1641 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0043 | 0.0121 | 0.0246 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0083 | 0.1035 | 0.4499 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0139 | 0.2301 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0043 | 0.0121 | 0.0246 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0211 | 0.0916 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0081 | 0.0992 | 0.4141 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0047 | 0.0211 | 0.0202 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0066 | 0.0643 | 0.207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0139 | 0.2301 | 1 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0139 | 0.2301 | 0.2706 |
Trichomonas vaginalis | esterase, putative | 0.0075 | 0.0854 | 0.3709 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0111 | 0.166 | 0.6934 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0043 | 0.0121 | 0.0085 |
Schistosoma mansoni | thyroid hormone receptor | 0.045 | 0.9354 | 1 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0139 | 0.2301 | 1 |
Onchocerca volvulus | 0.0081 | 0.0992 | 1 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.011 | 0.1658 | 0.7204 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0854 | 0.3686 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0043 | 0.0121 | 0.0095 |
Echinococcus granulosus | intermediate filament protein | 0.0081 | 0.0992 | 0.1138 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0075 | 0.0854 | 0.3713 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0139 | 0.2301 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0075 | 0.0854 | 0.5 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0111 | 0.166 | 0.6934 |
Loa Loa (eye worm) | intermediate filament protein | 0.0081 | 0.0992 | 0.4289 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0043 | 0.0121 | 0.0059 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0075 | 0.0854 | 0.3709 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0103 | 0.1495 | 0.6498 |
Onchocerca volvulus | 0.0081 | 0.0992 | 1 | |
Schistosoma mansoni | coup transcription factor | 0.0043 | 0.0121 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0043 | 0.0121 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Echinococcus multilocularis | lamin dm0 | 0.0081 | 0.0992 | 0.102 |
Brugia malayi | hypothetical protein | 0.0107 | 0.159 | 0.6821 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0119 | 0.1841 | 0.8002 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0043 | 0.0121 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0854 | 0.3686 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0103 | 0.1495 | 0.6498 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0043 | 0.0121 | 0.0085 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0043 | 0.0121 | 0.0246 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0211 | 0.0648 |
Mycobacterium ulcerans | lipase LipD | 0.0075 | 0.0854 | 0.5 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0139 | 0.2301 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0043 | 0.0121 | 0.0246 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0093 | 0.1266 | 0.5501 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0043 | 0.0121 | 0.0246 |
Echinococcus granulosus | FTZ F1 alpha | 0.0043 | 0.0121 | 0.0095 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0075 | 0.0854 | 0.5 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0075 | 0.0854 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0854 | 0.3686 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Brugia malayi | beta-lactamase family protein | 0.0075 | 0.0854 | 0.3524 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0139 | 0.2301 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0043 | 0.0121 | 0.0059 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0211 | 0.0916 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0043 | 0.0121 | 0.0246 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0139 | 0.2301 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0408 | 0.8389 | 1 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0139 | 0.2301 | 0.2426 |
Schistosoma mansoni | hypothetical protein | 0.0408 | 0.8389 | 0.8961 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0043 | 0.0121 | 0.0491 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0043 | 0.0121 | 0.0491 |
Onchocerca volvulus | 0.0075 | 0.0854 | 0.8414 | |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0043 | 0.0121 | 0.0095 |
Onchocerca volvulus | 0.0075 | 0.0854 | 0.8414 | |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0043 | 0.0121 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0958 | 0.4142 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0075 | 0.0852 | 0.3702 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0075 | 0.0854 | 0.3524 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0043 | 0.0121 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Schistosoma mansoni | intermediate filament proteins | 0.0081 | 0.0992 | 0.0997 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0139 | 0.2301 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0139 | 0.2301 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0075 | 0.0854 | 0.3075 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0081 | 0.0992 | 0.4289 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0043 | 0.0121 | 0.0085 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0043 | 0.0121 | 0.0246 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0107 | 0.159 | 0.1855 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0139 | 0.2301 | 1 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0058 | 0.0462 | 0.1204 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0059 | 0.0487 | 0.2088 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0992 | 0.4289 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0043 | 0.0121 | 0.0095 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0043 | 0.0121 | 0.0246 |
Brugia malayi | MH2 domain containing protein | 0.013 | 0.2106 | 0.9126 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0121 | 0.0491 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0111 | 0.166 | 0.6934 |
Mycobacterium ulcerans | hypothetical protein | 0.0075 | 0.0854 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0043 | 0.0139 | 0.0572 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0043 | 0.0121 | 0.0085 |
Mycobacterium leprae | conserved hypothetical protein | 0.0075 | 0.0854 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.993 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.955 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.86 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.818 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.79 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.753 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.748 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.741 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.