Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0854 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0477 | 0.0677 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0477 | 0.0677 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0854 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.1058 | 0.15 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.7054 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.1058 | 0.1058 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3341 | 0.3341 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0854 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.7054 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0854 | 0.121 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0477 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1027 | 0.1456 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0854 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0477 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0477 | 0.0677 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0182 | 0.0182 |
Onchocerca volvulus | 0.0026 | 0.1058 | 0.15 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0854 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.3341 | 0.4736 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0854 | 0.121 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.1058 | 0.15 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0152 | 0.0215 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0854 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0854 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0854 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0182 | 0.0259 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.3341 | 0.4736 |
Onchocerca volvulus | 0.0026 | 0.1058 | 0.15 | |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0854 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0152 | 0.0215 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.1058 | 0.1058 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.3341 | 0.4736 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.3341 | 0.3341 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0854 | 0.121 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0477 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0854 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0854 | 0.5 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0272 | 0.0386 |
Onchocerca volvulus | 0.0023 | 0.0854 | 0.121 | |
Brugia malayi | hypothetical protein | 0.0119 | 0.7054 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3341 | 0.3341 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0854 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.1058 | 0.15 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3341 | 0.3341 |
Brugia malayi | RNA binding protein | 0.0062 | 0.3341 | 0.4736 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.7054 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0182 | 0.0182 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0854 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.1058 | 0.15 |
Echinococcus multilocularis | musashi | 0.0026 | 0.1058 | 0.1058 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0272 | 0.0386 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0477 | 0.139 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3341 | 0.3341 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0477 | 0.0677 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0477 | 0.0677 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0854 | 1 |
Echinococcus multilocularis | lamin | 0.0026 | 0.1058 | 0.1058 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0854 | 0.121 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.3341 | 0.4736 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.3341 | 0.4736 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0854 | 1 |
Echinococcus granulosus | lamin | 0.0026 | 0.1058 | 0.1058 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0854 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.1058 | 0.1058 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0854 | 0.121 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0854 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0854 | 0.121 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.1058 | 0.1058 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.1058 | 0.1058 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3341 | 0.3341 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.7054 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.1058 | 0.1058 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1058 | 0.15 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.3341 | 0.3341 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0854 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.